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Ulrich Päßler konnte im September 2019 den verschollen geglaubten Brief von Carl Friedrich Gauß an Alexander von Humboldt vom 17. August 1832 wiederfinden. Dieser Brief stammt aus der Anfangsphase von Gauß’ erdmagnetischen Forschungen. Gauß gibt an, sich erst vor einem halben Jahr in dieses Gebiet gewagt zu haben, das bislang Humboldt vorbehalten war. Die wichtigsten Themen des Briefes sind der Einfluss der Temperatur auf die magnetischen Eigenschaften sowie die Methoden der Magnetisierung von Nadeln und Stäben. Der Brief füllt eine wichtige Lücke in der Korrespondenz zwischen Gauß und Humboldt und ergänzt unsere Kenntnisse über bisher kaum wahrgenommene Forschungsfelder von Gauß. Es wird eine kritische kommentierte Edition des Briefes vorgestellt.
Nach den beiden großen Forschungsreisen konzentrierte Ehrenberg seine Arbeit in Berlin auf die systematische Beschreibung von Kleinstlebewesen, die sogenannten Infusorien. 1838 erschien eines seiner Hauptwerke, Die Infusionsthierchen als vollkommene Organismen. Ein Blick in das tiefere organische Leben der Natur. Ehrenberg untersuchte tausende Proben aus aller Welt und wies Infusorien auf dem Grund der Weltmeere, in atmosphärischem Staub und in Hochgebirgen nach. Ausgehend von diesen Befunden beschäftigte er sich mit dem Anteil einzelliger kieselschaliger Mikroorganismen an der Bildung von Erden und geologischen Formationen. 1854 legte er die Mikrogeologie vor: In 41 Bildtafeln gab er weltweite „geographische Uebersichten über das kleine jetzige erdbildende Leben“. Christian Gottfried Ehrenberg gilt als Mitbegründer der Boden-Mikrobiologie und Mikropaläontologie sowie als Pionier der Kieselalgenforschung und Protozoologie.
„Eine der größten Freuden meines Lebens würde sein, einmal 5 – 6 Monathe mit Ihnen, an Ihrer Seite, unter Ihrer Belehrung reisen zu können. Süßwassermuscheln, Fische, Bergpflanzen Rußlands sind wenig bekannt.“ Mit diesen Worten lud Alexander von Humboldt seinen Akademiekollegen Ehrenberg zur Teilnahme an der russisch-sibirischen Reise ein, die der preußische Kammerherr auf Einladung des Kaisers Nikolaj I. unternahm. Knapp drei Jahre nach der Rückkehr von der arabisch-afrikanischen Forschungsreise brach Ehrenberg also erneut auf: Am 12. April 1829 traten Humboldt, Ehrenberg und der Mineraloge Gustav Rose ihre Reise in Berlin an. Diese führte sie in knapp neun Monaten und über 19 000 Kilometer in den Ural und durch Westsibirien bis zur russisch-chinesischen Grenzstation Baty. Während Humboldt und Rose die Hüttenbezirke im Ural und Altai inspizierten, legte Ehrenberg botanische und zoologische Sammlungen an.
Heinrich Menu von Minutoli unternahm 1820 eine Reise nach Nordafrika zur Erforschung ägyptischer und griechischer Altertümer. Die Preußische Akademie der Wissenschaften bestimmte die jungen Naturforscher Christian Gottfried Ehrenberg und Wilhelm Hemprich als weitere Teilnehmer.
Während Minutoli bereits ein Jahr nach Beginn der Expedition 1821 nach Europa zurückkehrte, setzten Ehrenberg und Hemprich ihre Forschungen fort. Von Alexandria aus unternahmen sie, zum Teil getrennt, Exkursionen in die libysche Wüste, auf die Sinaihalbinsel, zum Roten Meer, in das Libanongebirge sowie bis in den Sudan und nach Eritrea, wo Hemprich 1825 dem Malariafieber erlag.
Wie von der Akademie der Wissenschaften beauftragt, sammelten Ehrenberg und Hemprich insgesamt 34 000 Tiere, 46 000 Pflanzen und 300 Mineralien. Diese trafen im Laufe der Jahre, verpackt in insgesamt 114 Kisten, in Berlin ein. Die Akademie stellte Mittel für die Auswertung der Sammlungen zur Verfügung. Ehrenbergs Reisebericht blieb aber ebenso Fragment wie das großangelegte Tafelwerk Symbolae physicae.
Als langjähriges und aktives Mitglied der Gesellschaft Naturforschender Freunde zu Berlin bestimmte Ehrenberg ihre Aktivitäten und ihr Ansehen maßgeblich mit. Seine Beiträge zu den Sitzungen und Schriften und seine Rolle als Bewohner des gesellschaftseigenen Hauses förderten in der GNF sowohl Fortschritt als auch Beständigkeit. Das Ziel der Naturgeschichte des 18. Jahrhunderts, also die Entdeckung, Beschreibung und Bewahrung möglichst aller Organismen- und Gesteinsarten, wurde in der GNF bis in die zweite Hälfte des 19. Jahrhunderts tradiert. Ehrenbergs wissenschaftliche Leistungen, insbesondere seine zahlreichen Entdeckungen mit Hilfe des Mikroskops, stehen ganz in dieser Tradition.
Ab Mitte der 1820er Jahre erfuhr die Mikroskop- Technik eine stürmische Entwicklung. Dadurch, dass es gelang, nach und nach die optischen Fehler zu korrigieren, verbesserte sich die Auflösung bis zum Ende des Jahrhunderts um den Faktor 10 von 3 μm auf 0,3 μm. Um 1820 begann Christian Gottfried Ehrenberg mit mikroskopischen Untersuchungen. Er nutzte zunächst ein einfaches Nürnberger Mikroskop. 1832 erwarb er ein Mikroskop aus der Berliner Werkstatt von Pistor & Schiek, das er dann zeitlebens nutzte. Ein Vergleich der Leistungsfähigkeit seines Instruments mit der für seine Untersuchungen notwendigen Auflösung zeigt, dass es für seine Untersuchungen vollkommen genügte. Für seine Untersuchungsobjekte entwickelte er Präparationstechniken und Aufbewahrungsmethoden für die Dauerpräparate. Da er auch die mikroskopischen Abbildungen bis hin zu den Vorlagen für die Kupfertafeln selbst anfertigte, behielt er den gesamten Prozess von der Präparation bis zum Druck der Ergebnisse stets in der Hand.
Die Erforschung und Beschreibung mikroskopischer Organismen durch Christian Gottfried Ehrenberg ist durch seine publizierten Texte und Kupfertafeln in den „Infusionsthierchen“, der „Mikrogeologie“ sowie aus Abhandlungen der Akademie der Wissenschaften überliefert. Zentrale Bedeutung haben seine Zeichenblätter, anfangs alleinige Dokumentation, später komplementiert durch tausende mikroskopischer Dauerpräparate rezenter und fossiler Kieselschalen sowie getrockneter Einzeller. Alle Originalmaterialien Ehrenbergs stehen für die aktuelle Forschung in der Ehrenbergsammlung zur Verfügung. Seine detailgenauen Zeichnungen dienten der Erstbeschreibung einer Vielzahl neuer Arten aus allen Weltteilen. Biogeografische und ökologische Fragestellungen, Beschreibungen von Lebenszyklen sowie außerordentliche Phänomene wie die Färbung von Gewässern und Erden wurden mithilfe zeichnerischer Analysen bearbeitet.