AC electrokinetic immobilization of organic dye molecules
- The application of inhomogeneous AC electric fields for molecular immobilization is a very fast and simple method that does not require any adaptions to the molecule's functional groups or charges. Here, the method is applied to a completely new category of molecules: small organic fluorescence dyes, whose dimensions amount to only 1 nm or even less. The presented setup and the electric field parameters used allow immobilization of dye molecules on the whole electrode surface as opposed to pure dielectrophoretic applications, where molecules are attracted only to regions of high electric field gradients, i.e., to the electrode tips and edges. In addition to dielectrophoresis and AC electrokinetic flow, molecular scale interactions and electrophoresis at short time scales are discussed as further mechanisms leading to migration and immobilization of the molecules.
Verfasserangaben: | Eva-Maria LauxGND, Christian WengerORCiDGND, Frank Fabian BierORCiDGND, Ralph HoelzelORCiD |
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DOI: | https://doi.org/10.1007/s00216-020-02480-4 |
ISSN: | 1618-2642 |
ISSN: | 1618-2650 |
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/32125465 |
Titel des übergeordneten Werks (Englisch): | Analytical and bioanalytical chemistry : a merger of Fresenius' journal of analytical chemistry and Analusis |
Verlag: | Springer |
Verlagsort: | Berlin |
Publikationstyp: | Wissenschaftlicher Artikel |
Sprache: | Englisch |
Datum der Erstveröffentlichung: | 03.03.2020 |
Erscheinungsjahr: | 2020 |
Datum der Freischaltung: | 16.11.2023 |
Freies Schlagwort / Tag: | AC electrokinetics; AC electrophoresis; Interdigitated electrodes; Molecular dielectrophoresis; Organic dyes |
Band: | 412 |
Ausgabe: | 16 |
Seitenanzahl: | 12 |
Erste Seite: | 3859 |
Letzte Seite: | 3870 |
Fördernde Institution: | European Regional Development Fund (ERDF)European Commission; Brandenburg Ministry of Sciences, Research and Cultural Affairs (MWFK); [85004117]; German Research Foundation (DFG)German Research Foundation; (DFG) [SPP 1857HO1298/4-1] |
Organisationseinheiten: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
DDC-Klassifikation: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
Peer Review: | Referiert |
Publikationsweg: | Open Access / Hybrid Open-Access |
Lizenz (Deutsch): | CC-BY - Namensnennung 4.0 International |