Das Anliegen der vorliegenden Arbeit ist die Vermittlung des antiken Verhältnisses zwischen Mensch und natürlicher Umgebung im Lateinunterricht sowie ein Vergleich mit der heutigen Situation. Die Ergründung jenes Verhältnisses erfolgt am Beispiel des antiken Bergbaus, eines besonders anschaulichen Feldes der Umweltgeschichte. Denn es weist ein hohes Maß an Aktualität auf sowie ein großes Potential, aus der Beschäftigung mit ihm Erkenntnisse für die Gegenwart zu gewinnen. Vorgelegt wird eine Unterrichtskonzeption, die zugleich eine Analyse der menschlichen Naturwahrnehmung vornimmt. Zunächst wird dabei die Heterogenität dieser Wahrnehmung in der Antike aufgezeigt und in Bezug zur damals geäußerten Kritik am Bergbau gesetzt. Anschließend werden folgende Teilaspekte behandelt: 1. die antike bergbauliche Technik und Praxis, 2. die damals herrschenden Arbeitsbedingungen, 3. die gewonnenen Rohstoffe und ihre Verwendung sowie 4. die Folgen des Bergbaus für Mensch und Umwelt. Der didaktische Teil besteht aus einem Entwurf für drei Doppelstunden. Er enthält die Lehrmaterialien, die jeweiligen Erläuterungen und den Erwartungshorizont.

The Alpine mountains in central Europe are characterized by a heterogeneous crust accumulating different tectonic units and blocks in close proximity to sedimentary foreland basins. Centroid moment tensor inversion provides insight into the faulting mechanisms of earthquakes and related tectonic processes but is significantly aggravated in such an environment. Thanks to the dense AlpArray seismic network and our flexible bootstrap-based inversion tool Grond, we are able to test different setups with respect to the uncertainties of the obtained moment tensors and centroid locations. We evaluate the influence of frequency bands, azimuthal gaps, input data types, and distance ranges and study the occurrence and reliability of non-double-couple (DC) components. We infer that for most earthquakes (M-w >= 3.3) a combination of time domain full waveforms and frequency domain amplitude spectra in a frequency band of 0.02-0.07 Hz is suitable. Relying on the results of our methodological tests, we perform deviatoric moment tensor (MT) inversions for events with M-w > 3.0. Here, we present 75 solutions for earthquakes between January 2016 and December 2019 and analyze our results in the seismotectonic context of historical earthquakes, seismic activity of the last 3 decades, and GNSS deformation data. We study regions of comparably high seismic activity during the last decades, namely the Western Alps, the region around Lake Garda, and the eastern Southern Alps, as well as clusters further from the study region, i.e., in the northern Dinarides and the Apennines. Seismicity is particularly low in the Eastern Alps and in parts of the Central Alps. We apply a clustering algorithm to focal mechanisms, considering additional mechanisms from existing catalogs. Related to the N-S compressional regime, E-W-to-ENE-WSW-striking thrust faulting is mainly observed in the Friuli area in the eastern Southern Alps. Strike-slip faulting with a similarly oriented pressure axis is observed along the northern margin of the Central Alps and in the northern Dinarides. NW-SE-striking normal faulting is observed in the NW Alps, showing a similar strike direction to normal faulting earthquakes in the Apennines. Both our centroid depths and hypocentral depths in existing catalogs indicate that Alpine seismicity is predominantly very shallow; about 80% of the studied events have depths shallower than 10 km.

In a warming Arctic, permafrost-related disturbances, such as retrogressive thaw slumps (RTS), are becoming more abundant and dynamic, with serious implications for permafrost stability and bio-geochemical cycles on local to regional scales. Despite recent advances in the field of earth observation, many of these have remained undetected as RTS are highly dynamic, small, and scattered across the remote permafrost region. Here, we assessed the potential strengths and limitations of using deep learning for the automatic segmentation of RTS using PlanetScope satellite imagery, ArcticDEM and auxiliary datasets. We analyzed the transferability and potential for pan-Arctic upscaling and regional cross-validation, with independent training and validation regions, in six different thaw slump-affected regions in Canada and Russia. We further tested state-of-the-art model architectures (UNet, UNet++, DeepLabv3) and encoder networks to find optimal model configurations for potential upscaling to continental scales. The best deep learning models achieved mixed results from good to very good agreement in four of the six regions (maxIoU: 0.39 to 0.58; Lena River, Horton Delta, Herschel Island, Kolguev Island), while they failed in two regions (Banks Island, Tuktoyaktuk). Of the tested architectures, UNet++ performed the best. The large variance in regional performance highlights the requirement for a sufficient quantity, quality and spatial variability in the training data used for segmenting RTS across diverse permafrost landscapes, in varying environmental conditions. With our highly automated and configurable workflow, we see great potential for the transfer to active RTS clusters (e.g., Peel Plateau) and upscaling to much larger regions.

The formation of the Central Andes dates back to similar to 50 Ma, but its most pronounced episode, including the growth of the Altiplano-Puna Plateau and pulsatile tectonic shortening phases, occurred within the last 25 Ma. The reason for this evolution remains unexplained. Using geodynamic numerical modeling we infer that the primary cause of the pulses of tectonic shortening and growth of the Central Andes is the changing geometry of the subducted Nazca plate, and particularly the steepening of the mid-mantle slab segment which results in a slowing down of the trench retreat and subsequent increase in shortening of the advancing South America plate. This steepening first happens after the end of the flat slab episode at similar to 25 Ma, and later during the buckling and stagnation of the slab in the mantle transition zone. Processes that mechanically weaken the lithosphere of the South America plate, as suggested in previous studies, enhance the intensity of the shortening events. These processes include delamination of the mantle lithosphere and weakening of foreland sediments. Our new modeling results are consistent with the timing and amplitude of the deformation from geological data in the Central Andes at the Altiplano latitude. Plain Language Summary The Central Andes is a subduction-type orogeny that formed as a result of the interaction between the Nazca oceanic plate and the South American continental plate over the last 50 million years. Growth of the Andes is primarily the result of crustal shortening. Nevertheless, "geological" data compiled from previous studies have shown that phases of drastic pulsatile shortening occur at 15 and 5 Ma. In this study, we used high-resolution 2D numerical geodynamic simulations to investigate the link between oceanic and continental plate dynamics and their interaction. We find that when the oceanic plate steepens in the mantle transition zone, the trench retreat is hindered. Coupled with the weakening of the continental plate through the slab flattening and subsequent delamination of the lithospheric mantle, this leads to pulsatile shortening phases of a magnitude equivalent to that suggested by the data.

Drimys winteri J.R. (Winteraceae) produce drimane sesquiterpenoids with activity against Candida yeast. In this work, drimenol, polygodial (1), isotadeonal (2), and a new drimane alpha,beta-unsaturated 1,4-dialdehyde, named winterdial (4), were purified from barks of D. winteri. The oxidation of drimenol produced the monoaldehyde drimenal (3). These four aldehyde sesquiterpenoids were evaluated against six Candida species isolated from candidemia patients in Chilean hospitals. Results showed that 1 displays fungistatic activity against all yeasts (3.75 to 15.0 mu g/mL), but irritant effects on eyes and skin, whereas its non-pungent epimer 2 has fungistatic and fungicide activities at 1.9 and 15.0 mu g/mL, respectively. On the other hand, compounds 3 and 4 were less active. Molecular dynamics simulations suggested that compounds 1-4 are capable of binding to the catalytic pocket of lanosterol 14-alpha demethylase with similar binding free energies, thus suggesting a potential mechanism of action through the inhibition of ergosterol synthesis. According to our findings, compound 2 appears as a valuable molecular scaffold to pursue the future development of more potent drugs against candidiasis with fewer side effects than polygodial. These outcomes are significant to broaden the alternatives to treat fungal infections with increasing prevalence worldwide using natural compounds as a primary source for active compounds.