Extern
Refine
Year of publication
Document Type
- Article (193)
- Doctoral Thesis (126)
- Monograph/Edited Volume (69)
- Working Paper (36)
- Postprint (19)
- Conference Proceeding (9)
- Preprint (7)
- Master's Thesis (5)
- Part of Periodical (4)
- Habilitation Thesis (2)
Language
- English (347)
- German (130)
- Portuguese (1)
Is part of the Bibliography
- yes (478) (remove)
Keywords
- Arktis (6)
- climate change (6)
- Arctic (5)
- COVID-19 (5)
- Lehrkräftebildung (5)
- Reflexion (5)
- football (5)
- Fernerkundung (4)
- exercise (4)
- machine learning (4)
- Chlamydomonas (3)
- Feedback (3)
- Holozän (3)
- Klimawandel (3)
- Kohlenstoff (3)
- Nanopartikel (3)
- attention (3)
- carbon (3)
- climate policy (3)
- cluster expansion (3)
- diabetes (3)
- energy policy (3)
- entrepreneurship (3)
- entropy (3)
- gender (3)
- infinite-dimensional Brownian diffusion (3)
- kinetics (3)
- language acquisition (3)
- molecular motors (3)
- molekulare Motoren (3)
- obesity (3)
- photosynthesis (3)
- remote sensing (3)
- stunting (3)
- Akan (2)
- Anden (2)
- Andes (2)
- Animal personality (2)
- Antarctica (2)
- Antarktis (2)
- Argentina (2)
- Argentinien (2)
- Atmosphäre (2)
- Bildungswissenschaften (2)
- Brandenburg (2)
- Datenanalyse (2)
- Digitalisierung (2)
- E. coli (2)
- Energiespeicher (2)
- Energy expenditure (2)
- Entrepreneurship (2)
- European hare (2)
- Fontane, Theodor (2)
- Forschungsdaten (2)
- Forschungsdatenmanagement (2)
- GIS (2)
- GPS (2)
- Galaxien (2)
- Geodynamik (2)
- Germany (2)
- Gesellschaft (2)
- Graphentheorie (2)
- Holocene (2)
- Human Rights (2)
- Informatikdidaktik (2)
- Inter-individual differences (2)
- Jurkat cells (2)
- Kohlenstoffnitriden (2)
- Korrosion (2)
- LC/HRMS (2)
- Lidar (2)
- Magnetismus (2)
- Magnetohydrodynamik (2)
- Medialisierung (2)
- Menschenrechte (2)
- MiSpEx (2)
- Movement ecology (2)
- N400 (2)
- ODBA (2)
- Partial Little Square (2)
- Physical activity (2)
- Potsdam (2)
- Presse (2)
- Quantitative Trait Locus (2)
- Quantitative Trait Locus analysis (2)
- Rechtsvergleichung (2)
- Reflexivität (2)
- Regionalentwicklung (2)
- Rheologie (2)
- Rheology (2)
- SEPE (2)
- SNARC (2)
- Schadensmodellierung (2)
- Seesedimente (2)
- Seismologie (2)
- Spektroskopie (2)
- Stoffwechsel (2)
- Summer Schools (2)
- Systembiologie (2)
- Transformation (2)
- Union (2)
- Virus (2)
- acclimation (2)
- achilles tendinopathy (2)
- adipose tissue (2)
- air-water interface (2)
- amino acids (2)
- anterior PNP (2)
- antibody (2)
- atmosphere (2)
- behaviour (2)
- body height (2)
- carbon cycling (2)
- carbon nitrides (2)
- carbon pricing (2)
- composition (2)
- constraint (2)
- corrosion (2)
- cosmic rays (2)
- derivational complexity (2)
- diffusion (2)
- digitalization (2)
- drug delivery (2)
- ecophysiology (2)
- education (2)
- educational sciences (2)
- electrochemistry (2)
- electromyography (2)
- energy expenditure (2)
- energy storage (2)
- europe (2)
- european (2)
- experiment (2)
- feature selection (2)
- flexibility (2)
- galaxies (2)
- global change (2)
- governance (2)
- grammaticalization (2)
- graph theory (2)
- handgrip strength (2)
- health care (2)
- heterogene Photokatalyse (2)
- heterogeneous photocatalysis (2)
- human excised skin (2)
- hydrolysis (2)
- kosmische Strahlung (2)
- literature review (2)
- local governance (2)
- lokale Governance (2)
- long-term effects (2)
- longitudinal (2)
- low back pain (2)
- magnetohydrodynamics (2)
- malnutrition (2)
- maturation (2)
- mechanobiology (2)
- mental health (2)
- miRNA (2)
- migration (2)
- monensin (2)
- multidisciplinary intervention (2)
- nanogels (2)
- organic synthesis (2)
- organische Synthese (2)
- permafrost (2)
- photoresponse (2)
- physiology (2)
- political ideology (2)
- posterior P600 (2)
- pre-school (2)
- predictability (2)
- probabilistic processing (2)
- recombinant inbred line (2)
- reflexion (2)
- renewable energy (2)
- research data management (2)
- school mathematics (2)
- seismology (2)
- self-assembly (2)
- self-employment (2)
- skills (2)
- skin penetration (2)
- spatial autocorrelation (2)
- spatially explicit (2)
- stability (2)
- stable isotopes (2)
- stochastic processes (2)
- stochastische Prozesse (2)
- sustainability (2)
- tacrolimus formulation (2)
- transformation (2)
- transformation products (2)
- veterinary drugs (2)
- virtual reality (2)
- virus (2)
- wh-ex-situ (2)
- wh-in-situ (2)
- wh-questions (2)
- wheat (2)
- 19. Jahrhundert (1)
- 19th century (1)
- 2-deoxy-D-ribose-5-phoshphate aldolase (1)
- 2D Numerical Modelling (1)
- 3D thermal model (1)
- 3DCityDB (1)
- 5-methoxycarbonylmethyl-2-thiouridine (1)
- AC Elektrokinetik (1)
- AC Elektroosmosis (1)
- AC electrokinetics (1)
- AC electroosmosis (1)
- ACWR (1)
- AFLP (1)
- AG "Weser" Solidarność Leninwerft (1)
- AGN (1)
- ALOS World 3D (1)
- APP (1)
- ARMS (1)
- ASPECT (1)
- ASTER GDEM (1)
- Absolventenstudie (1)
- Acetylcholin (1)
- Active Labor Market Policy (1)
- Adipose tissue (1)
- Adolescents (1)
- Adsorption (1)
- Adult-child interaction (1)
- Advection and convection (1)
- Aerosole (1)
- Aerosols (1)
- Africa (1)
- Aftercare (1)
- Aging (1)
- Akt pathway (1)
- Aktiven Galaxienkerne (1)
- Albanien (1)
- Allgemeiner Jüdischer Arbeiterbund (1)
- Alliierte Militärverbindungsmissionen (1)
- Alternative Bildung (1)
- Altiplano (1)
- Aluminiumlegierung (1)
- Alzheimer's Disease (1)
- Aminosäuren (1)
- Anpassung (1)
- Anthropologie (1)
- Antibiotic alternatives (1)
- Antibiotic resistance (1)
- Antibiotikaersatz (1)
- Antibiotikaresistenz (1)
- Antifouling (1)
- Antikörper (1)
- Antwortmengenprogrammierung (1)
- Application Server (1)
- Arabica coffee (1)
- Arabidopsis thaliana (1)
- Arbeit (1)
- Archetyp (1)
- Arctic aerosol (1)
- Arctic haze (1)
- Arctic tundra (1)
- Assemblierungsfaktor (1)
- Association Rule Mining (1)
- Assoziationsregeln (1)
- Astronomie (1)
- Asynchrone Schaltung (1)
- Asynchronous circuit (1)
- Atmosphärenforschung (1)
- Atomwaffen (1)
- Aufmerksamkeit (1)
- Auftaktworkshop (1)
- Auftragsabwicklung (1)
- Auftragsabwicklungssysteme (1)
- Backward ownership (1)
- Bacteria (1)
- Bakterien (1)
- Barriers (1)
- Basalt-Vulkane (1)
- Bay of Bengal (1)
- Bayesian Network (1)
- Bayesian modelling (1)
- Bayesianisches Netzwerk (1)
- Bayesianism (1)
- Bayesianismus (1)
- Bedarfsanalyse (1)
- Bedingte Inklusionsabhängigkeiten (1)
- Bemessungshochwasser (1)
- Berufspraktische Studien (1)
- Beschichtungen (1)
- Besitzschutz (1)
- Beta-Lactoglobulin (1)
- Beta-Zelle (1)
- Bewegung (1)
- Beweidung (1)
- Bi2Se3 (1)
- Bi2Te3 (1)
- Bildung (1)
- Bindungsinteraktion (1)
- Biofilm (1)
- Biogenese (1)
- Biografie (1)
- Biokonjugate (1)
- Biomarker (1)
- Biomoleküle (1)
- Bioraffinerie (1)
- Blattverschiebung (1)
- Boden (1)
- Bodenunruhe (1)
- Borna Disease Virus (1)
- Borna disease virus (1)
- Brandenburgisch-Niederlausitzische Landesgeschichte (1)
- Bruchmodel (1)
- Bucht von Bengalen (1)
- Bulge (1)
- Bund (1)
- Bundesländer (1)
- Bundesnachrichtendienst (1)
- Bundeswehr (1)
- Bundeswehrkommando Ost (1)
- CCSEM (1)
- CDF (1)
- CDOM (1)
- COVID-19 pandemic (1)
- CRISPR editing validation (1)
- CSC (1)
- Caco-2 (1)
- Canonical Gibbs measure (1)
- Cantor (1)
- Carbon Capture (1)
- Carbon Dioxide Removal (1)
- Cars (1)
- Causal structure (1)
- Central European Basin System (1)
- Chaco-Paraná Becken (1)
- Chaco-Paraná basin (1)
- Chalkogenide (1)
- Chazzan (1)
- Chemokinematik der Milchstraße (1)
- Chew Bahir (1)
- China (1)
- Chloroplast transformation (1)
- Chloroplastentransformation (1)
- Chronic conditions (1)
- Chronic low back pain (1)
- Chunking (1)
- Citrazinsäure (1)
- CityGML (1)
- Citymodel (1)
- Clay Minerals (1)
- Climate Policy (1)
- Climate reconstruction (1)
- Clustering (1)
- Cognitive fatigue (1)
- Cold War (1)
- Communication (1)
- Complex networks (1)
- Computer Science Education (1)
- Conditional Inclusion Dependency (1)
- Conflicts (1)
- Continental Rifts (1)
- Controller-Resynthese (1)
- Conversation Analysis (1)
- Copernicus DEM (1)
- Coping (1)
- Covid-19 (1)
- Cross-frequency PLV (1)
- Cu doped InP (1)
- Cu-dotiertes InP (1)
- Cystic fibrosis (1)
- Cytochrome b (1)
- DAS (1)
- DEM noise (1)
- DGVM (1)
- Damage assessment (1)
- Daseinsvorsorge (1)
- Data Dependency (1)
- Data pooling (1)
- Data-Mining (1)
- Database (1)
- Datenabhängigkeiten (1)
- Datenbank (1)
- Datendokumentation (1)
- Datenintegration (1)
- Datenschutzgrundverordnung (1)
- Deformation (1)
- Deligne Cohomology (1)
- Deligne Kohomologie (1)
- Delphi study (1)
- Demografie (1)
- Demokratisierung (1)
- Density modelling (1)
- Deoxyfructosazin (1)
- Desambiguierung (1)
- Deutschland (1)
- Developmental hyperscanning (1)
- Diabetes (1)
- Diamantstempelzelle (1)
- Diatomeen (1)
- Diatoms (1)
- Dichtemodellierung (1)
- Dielektrophorese (1)
- Difference-in-Differences (1)
- Digital Health (1)
- Digital intervention (1)
- Diskursverstehen (1)
- Disturbance impacts (1)
- Disturbance indicator (1)
- Disziplinspezifisches FDM (1)
- Diversität (1)
- Drittwirkung (1)
- Dronning Maud Land (1)
- Dual EEG analysis (1)
- Durchmusterung (1)
- Dynamometry (1)
- E-DSGE (1)
- EAAT1 (1)
- EEG (1)
- EKP (1)
- ERP (1)
- ETV (1)
- Early New High German (1)
- Earthquake (1)
- Eating behavior (1)
- Eccentric muscle action (1)
- Ecology (1)
- Ecotoxicology (1)
- Einkapselung (1)
- Einzelatomkatalyse (1)
- Eisbohrkern (1)
- Ejina Basin (1)
- Ejina Becken (1)
- Electron acceleration (1)
- Electronic Health (1)
- Elektronenbeschleunigung (1)
- Elephant disturbance (1)
- Embodied cognition (1)
- Emissionslinienklassifikation (1)
- Employee Training (1)
- Emulsion (1)
- Entry deterrence (1)
- Entstehung der Milchstraße (1)
- Erdbeben (1)
- Erdmantel (1)
- Ereigniskorreliertes Potenzial (1)
- Erkennen von Meta-Daten (1)
- Erkenntnisgewinnung (1)
- Ernährung (1)
- Etna (1)
- Europa (1)
- Europe (1)
- Evangelische Kirchen- und Kunstgeschichte (1)
- Evolution (1)
- Evolution der Milchstraße (1)
- Exertion (1)
- Exoplaneten (1)
- Exoplanetenatmosphären (1)
- Exportsubvention (1)
- FARIMA (1)
- FastScape (1)
- Feature selection (1)
- Federal Armed Forces of Germany (1)
- Federal Foreign Intelligence Service (1)
- Ferroperiklas (1)
- FieldTrip (1)
- Figurative Sprachverarbeitung (1)
- Figurative language processing (1)
- Finite-State Maschinen (1)
- Firm Growth (1)
- Fiskalregeln (1)
- Flache Subduktion (1)
- Flat subduction (1)
- Flow-Erleben (1)
- Flow-experience (1)
- Fluorescence (1)
- Fluorpolymere (1)
- Flächenutzungswandel (1)
- Foreclosure (1)
- Foreland (1)
- Foreland basin (1)
- Foreland basins (1)
- Forschendes Lernen (1)
- Forschungsmethodik (1)
- Forschungsorientierung (1)
- Forstwirtschaft (1)
- Fortbildung (1)
- Fourier analysis (1)
- Frederick II. (1)
- Freizeit (1)
- Frequenzanalyse (1)
- Fresh water fish (1)
- Friedrich II. (1)
- Frucht (1)
- Fundamental Modeling Concepts (1)
- GC-MS (1)
- GITEWS (1)
- Gait (1)
- Galaxie: allgemein (1)
- Galaxienhaufen (1)
- Gasgeochemie (1)
- Gassorption (1)
- Gaxun Nur (1)
- Gen-Koexpression (1)
- Gender Forschung (1)
- Gender studies (1)
- Gene co-expression (1)
- Gene expression (1)
- General Data Protection Regulation (1)
- General Jewish Workers (1)
- Genetics (1)
- Genisa (1)
- Geniza (1)
- Geodynamic Modelling (1)
- Geodynamics (1)
- Geodynamische Modellierung (1)
- Geothermal field (1)
- Gerben (1)
- Gerbes (1)
- German reunification (1)
- Geschmacksrezeptor (1)
- Geschwindigkeitsmodell (1)
- Gesellschaftrecht (1)
- Gesundheitsförderung (1)
- Gibbs field (1)
- Gibbs measure (1)
- Gleichaltrigenbeziehungen (1)
- Gletschervorfeld (1)
- Global Differentialgeometry (1)
- Globale Differentialgeometrie (1)
- Glucolipotoxizität (1)
- Glucose homeostasis (1)
- Glutamat (1)
- Glutamate (1)
- Glykan-Protein-Wechselwirkung (1)
- Glykopolymere (1)
- Glück/Zufriedenheit (1)
- Gold (1)
- Governance (1)
- Grabenbrüche (1)
- Greenhouse Gas Emissions (1)
- Greenland (1)
- Grenzflächenchemie (1)
- Grenzschicht (1)
- Grenzüberschreitende Kooperation (1)
- Grip force (1)
- Growth signaling (1)
- Gruppe der Sowjetischen Streitkräfte in Deutschland (1)
- Grönland (1)
- Grüne Chemie (1)
- Gyrochronologie (1)
- H/V (1)
- H2S biosynthesis (1)
- HDL (1)
- HIV (1)
- HMA (1)
- HVSR (1)
- Hamstring-quadriceps ratio (1)
- Handlungsempfehlungen (1)
- Harnstoff-Glas-Route (1)
- Hauptfaserbündel (1)
- Health insurance (1)
- Heat transport by conduction (1)
- Heavy Minerals (1)
- Heihe (1)
- HepG2 (1)
- Heptazine (1)
- Herkunftsanalyse (1)
- High growth firms (1)
- Hippo signaling (1)
- Hochdruck (1)
- Hochschuldidaktik (1)
- Hochschule (1)
- Hochschulverlage (1)
- Hochwasserrisiko (1)
- Holonomie (1)
- Holonomy (1)
- Horizontal flux (1)
- Human Capital Investments (1)
- Human physical conditioning (1)
- Hyperakkumulation (1)
- Hysterese (1)
- IBM 360 (1)
- ICDP (1)
- ICP OES (1)
- ICT (1)
- ICT competencies (1)
- IRF3 (1)
- ISSEP (1)
- Immunoassay (1)
- Impakt (1)
- Impermanence (1)
- Importin (1)
- InSAR (1)
- Indian Summer Monsoon (1)
- Indischer Sommermonsun (1)
- Individualized therapy (1)
- Industrieunternehmen (1)
- Influenza (1)
- Informatics (1)
- Informatics Education (1)
- Informatik (1)
- Informatische Kompetenzen (1)
- Injury (1)
- Injury risk (1)
- Inklusion (1)
- Inlandeis (1)
- Innovation (1)
- Institut (1)
- Institutionalisierung (1)
- Institutions (1)
- Instrumente: Polarimeter (1)
- Instrumente: Spektrographen (1)
- Insulin resistance (1)
- Intelligence history (1)
- Interacting Diffusion Processes (1)
- Interactional Linguistics (1)
- Interactors (1)
- Interaktoren (1)
- Interferon <beta-> (1)
- Internet of Things (1)
- Interoception (1)
- Interoperability (1)
- Interoperalität (1)
- Introgression (1)
- Intuitive eating (1)
- Inversion (1)
- Ionenmobilitätspektrometrie (1)
- Iron Age (1)
- Irradiation (1)
- Island biogeography (1)
- Java 2 Enterprise Edition (1)
- Java Virtual Machine (1)
- Jets (1)
- Jewish Berlin (1)
- Jewish Studies (1)
- Jewish liturgy (1)
- Jewry/Judaism (1)
- Jiddisch (1)
- Job Creation (1)
- Job Search (1)
- Judentum (1)
- Just so stories (1)
- Juvenile idiopathic arthritis (1)
- Jüdische Liturgie (1)
- Jüdische Studien (1)
- Jüdisches Berlin (1)
- KI-Anwendung (1)
- Kalter Krieg (1)
- Kantor (1)
- Karbonnitrid Ionothermalsynthese (1)
- Kathode (1)
- Kausalstruktur (1)
- Kern-Mantel Grenze (1)
- Kernlokalisierungssignal (1)
- Key Competencies (1)
- Kickoff Workshop (1)
- Kinderrechte (1)
- Kindertagesstätten (1)
- Klimadaten (1)
- Klimanetzwerke (1)
- Klimaphysik (1)
- Klimapolitik (1)
- Klimarekonstruktion (1)
- Klimaschutz (1)
- Klimavariabilität (1)
- Kognition (1)
- Kohlenstoffhaushalt (1)
- Kohlenstoffkreislauf (1)
- Kohlenstoffmaterialien (1)
- Kohlenstoffmodell (1)
- Kohnen (1)
- Kommunalwissenschaft (1)
- Kommune (1)
- Kommunikation (1)
- Kompetenzen (1)
- Komplexe Netzwerke (1)
- Konflikte (1)
- Konflikte: Deutsche Christen vs. Bekennende Kirche (1)
- Konflikte: Lutheraner vs. Calvinisten (1)
- Kriminalpolitik (1)
- Kultivierung (1)
- Künstliche Intelligenz (1)
- K−12 teachers (1)
- LAEs (1)
- LC-MS/MS (1)
- LCSM (1)
- LC–MS/MS (1)
- LDL (1)
- LOC (1)
- LPJ (1)
- Labor Market Mobility (1)
- Lake Holzmaar (1)
- Lake Malawi (1)
- Lake sediments (1)
- Langevin Dynamics (1)
- Laser ablation (1)
- Lateglacial (1)
- Lavafontänen (1)
- Lebensstil (1)
- Lehramtsstudium (1)
- Lehramtsstudium Biologie (1)
- Lehre (1)
- Lehrerbildung (1)
- Leitentscheidungen (1)
- Lektine (1)
- Levy walks (1)
- Li-Batterien (1)
- Li-Ionen-Akkus (1)
- Li-Ionen-Kondensator (1)
- Li-batteries (1)
- Li-ion batteries (1)
- Li-ion capacitor (1)
- LiFePO4 (1)
- Lignin (1)
- Link Discovery (1)
- Link-Entdeckung (1)
- Linked Open Data (1)
- Locally structured correlation (1)
- Locally structured standard deviation (1)
- Lokalisierung von Deformation (1)
- Lyman Kontinuum (1)
- Lyman alpha (1)
- Lyman continuum (1)
- Lyman-Alpha-Emitter (1)
- Lyman-alpha emitters (1)
- Lysimeter (1)
- Ländliches Judentum (1)
- M1/M2 differentiation (1)
- MALDI-TOF-MS (1)
- MCI (1)
- MSAP (1)
- MSPAC (1)
- MTP (1)
- MTP1 (1)
- MTP2 (1)
- MTP3 (1)
- Macht (1)
- Magnetfelder (1)
- Magnetoelastizität (1)
- Malliavin calculus (1)
- Manager Decisions (1)
- Mandarin-English bilinguals (1)
- Markov chains (1)
- Markov processes (1)
- Markov-Prozesse (1)
- Markovketten (1)
- Martial arts (1)
- Maschinelles Lernen (1)
- Massenspektrometrie (1)
- Massenverlust (1)
- Matthew effect (1)
- Maximum-Likelihood (1)
- Mechanobiologie (1)
- Mediation (1)
- Medienbildung (1)
- Meereis (1)
- Mental number line (1)
- Mesokristalle (1)
- Mesoporosity (1)
- Mesoporosität (1)
- Metabolic syndrome (1)
- Metabolism (1)
- Metabolit (1)
- Metabolome (1)
- Metadata Discovery (1)
- Metadatenentdeckung (1)
- Metadatenqualität (1)
- Meteorologie (1)
- Methankreislauf (1)
- MiSpEx-network (1)
- Microschwimmer (1)
- Microtus arvalis (1)
- Mikrofluidik (1)
- Mikrokapseln (1)
- Mikroplatte (1)
- Mikrowellensynthese (1)
- Mikrozonierung (1)
- Militärgeschichte (1)
- Milky Way chemo-kinematics (1)
- Milky Way evolution (1)
- Milky Way formation (1)
- Mindfulness (1)
- Minority shareholdings (1)
- Mitochondria (1)
- Mitochondrien (1)
- Mixed methods (1)
- Mobile Health (1)
- Mobile diagnostics (1)
- Moco biosynthesis (1)
- Modeling (1)
- Modellierung (1)
- Mondsee (1)
- Monte Carlo method (1)
- Monte-Carlo simulation (1)
- Morbus Alzheimer (1)
- Morphologie von Kapseln (1)
- Motor system (1)
- Movement (1)
- Muscle strength (1)
- Musculoskeletal and neural physiological phenomena (1)
- Musikunterricht (1)
- Muttergalaxien (1)
- NAFLD/MAFLD (1)
- NZO (1)
- Nachrichtendienstgeschichte (1)
- Nano (1)
- Nanoelektroden (1)
- Natrium-Ionen-Akkumulator (1)
- Natural Language Processing (1)
- Naturparks (1)
- Needs Analysis (1)
- Neutronensterne (1)
- Nichtlineare Spektroskopie (1)
- Nichtlineare Wellen (1)
- Nicotin (1)
- Niederschlesien (1)
- Niedersorbische Sprach- und Kulturgeschichte (1)
- Nitrat (1)
- Nitride (1)
- Nitrides (1)
- Non-invasive vagus nerve stimulation (1)
- Nonlinear waves (1)
- Noradrenaline (1)
- Nordböhmisches Gebiet (1)
- Nuklearwaffen (1)
- Number processing (1)
- Numerische 2D Modellierung (1)
- NutriAct Family Study (1)
- Nutrition (1)
- Oberflächenbeschichtung (1)
- Oberflächenchemie (1)
- Oberflächenprozesse (1)
- Oberflächenzustände (1)
- Obesity (1)
- Old High German (1)
- Older adults (1)
- Oligopol (1)
- Omicron (1)
- Ontologie (1)
- Open Access (1)
- OpenStreetMap (1)
- Orogen (1)
- Ortscharakterisierung (1)
- Ortseffekte (1)
- Oscillating Bubble (1)
- Overhead athletes (1)
- Oxinitride (1)
- Oxynitrides (1)
- P-Typ ATPase (1)
- PAVM (1)
- PBCEC (1)
- PHQ-4 score (1)
- PHREEQC (1)
- PLV (1)
- PM10, PM2, PM1 (1)
- POC (1)
- PUFA (1)
- Paleofloods (1)
- Paläohochwasser (1)
- Paläoklima (1)
- Paläolimnologie (1)
- Partial ownership (1)
- Partnership (1)
- Patholinguistik (1)
- Peptid-Polymer-Konjugate (1)
- Permafrost (1)
- Permafrostdegradation (1)
- Permafrostsedimente (1)
- Permafrostökosysteme (1)
- Perowskite (1)
- Personalbedarfsplanung (1)
- Personenbezogene Daten (1)
- Petrinetz (1)
- Phage lysins (1)
- Phagenlysine (1)
- Phase Locking Value (1)
- Philosophie (1)
- Phosphatidylethanolamin (1)
- Phosphatidylserin (1)
- Phosphatidylserin Decarboxylase (1)
- Phospholipide (1)
- Phosphoproteomik (1)
- Photochemische Reaktionen (1)
- Photodynamics (1)
- Photosynthese (1)
- Photosystem I (1)
- Phylogeny (1)
- Physical training (1)
- Piano delle Concazze (1)
- Pipistrellus nathusii (1)
- Pkw (1)
- Planetary Rings (1)
- Plyometric exercise (1)
- Policy Reform (1)
- Pollen (1)
- Polyether (1)
- Polymerisation (1)
- Polymernetzwerk (1)
- Polyneuropathie (1)
- Popularity (1)
- Populationsdynamik (1)
- PostGIS (1)
- Postural control (1)
- Power (1)
- Pragmatik (1)
- Praxissemester (1)
- Present-Day German (1)
- Preußen (1)
- Prevention (1)
- Prinicipal Fibre Bundles (1)
- Prior knowledge (1)
- Procrustes rotation analysis (1)
- Professionalisierung (1)
- Professionswissen (1)
- Progressive Education (1)
- Prokrustes Analyse (1)
- Propeller (1)
- Prospective (1)
- Protective factors (1)
- Proteom (1)
- Protonenleitfähigkeit (1)
- Provenance Analysis (1)
- Proxyunsicherheit (1)
- Proxyverständnis (1)
- Prussia (1)
- Pseudodatensätze (1)
- Psychologie (1)
- Psychosoziale Gesundheit (1)
- Publication Processes (1)
- Publikationsprozesse (1)
- Puna (1)
- Push and Pull Theories (1)
- QD device (1)
- QD stability (1)
- QD-Gerät (1)
- QD-Stabilität (1)
- QtClassify (1)
- Qualitative Forschungsdaten (1)
- Quality of life (1)
- Quality of regional governments (1)
- Qualität der Lehre (1)
- RAVE Beobachtungskampagne (1)
- RAVE survey (1)
- Random Field Ising Model (1)
- Randomized controlled trial (1)
- Randomized-controlled trial (1)
- Rationalität (1)
- Recht auf Bildung (1)
- Rechtsgeschichte (1)
- Rechtswissenschaft (1)
- Referendariat (1)
- Reflection (1)
- Reflection Skills (1)
- Reflexionskompetenz (1)
- Reflexivity (1)
- Regelkreismechanismus (1)
- Regions (1)
- Regulation (1)
- Rehabilitation (1)
- Reionisierung (1)
- Relativistische Astrophysik (1)
- Remote Sensing (1)
- Repetition (1)
- Reproducible benchmarking (1)
- Resiliency (1)
- Resistance training (1)
- Rezeptor (1)
- Rift (1)
- Right to Education (1)
- Rights of Children (1)
- Risk Attitudes (1)
- Ritual (1)
- Rotation (1)
- Rotifera (1)
- Rural Jewry (1)
- Rural health (1)
- Russian Arctic (1)
- Röntgenbeugung (1)
- Röntgenkleinwinkelstreuung (1)
- SAR (1)
- SARS-CoV-2 (1)
- SEGUE Beobachtungskampagne (1)
- SEGUE survey (1)
- SEPE Factors (1)
- SEPS factors (1)
- SFA (1)
- SFON (1)
- SPAC (1)
- SRT (1)
- SRTM (1)
- STG decomposition (1)
- STG-Dekomposition (1)
- Sachsen (1)
- Salzgestein (1)
- Salzschmelze (1)
- Salzschmelze-Templating (1)
- Sammelband (1)
- Schaum (1)
- Scheibe (1)
- Schemaentdeckung (1)
- Schiffbau (1)
- Schlüsselkompetenzen (1)
- Schlüsselkompetenzen (1)
- Schuldenbremse (1)
- Schulpraktikum (1)
- Schwerminerale (1)
- Search Frictions (1)
- Sedimentary basin (1)
- Seehandlung (1)
- Segmentierung (1)
- Selbstheilende Beschichtungen (1)
- Selbstorganisation (1)
- Selbstreflexion (1)
- Selen (1)
- Selenonein (1)
- Seminarkonzept (1)
- Shire River (1)
- Shock waves (1)
- Shortening (1)
- Shoulder (1)
- Sierras Pampeanas (1)
- Signalflankengraph (SFG oder STG) (1)
- Silika (1)
- Simulationen (1)
- Social Cost of Carbon (1)
- Social Status (1)
- Social-Economic-Political-Emotional (SEPE) factors (1)
- Sociometry (1)
- Solar corona (1)
- Sonne: Oszillationen (1)
- Sonne: Sonnenflecken (1)
- Sonnenkorona (1)
- Sorbisch-Deutsche Kulturkontakte (1)
- South-Eastern Africa (1)
- Soziale Medien (1)
- Soziale Ungleichheit (1)
- Sozialer Status (1)
- Sozialismus (1)
- Sozialversicherungssystem (1)
- Soziometrie (1)
- Space-Time Cluster Expansions (1)
- Spalteneruption (1)
- Spannungsfeld (1)
- Specific wood density (1)
- Spinpolarisation (1)
- Spionage (1)
- Spleißvariante (1)
- Splice Variant (1)
- Split Ubiquitin (1)
- Sport-specific performance (1)
- Sprachbildung (1)
- Sprachtherapie (1)
- Spurengasflüsse (1)
- Spätglazial (1)
- St. Nicolas House Analysis (1)
- Staatsverschuldung (1)
- Stabile Isotope (1)
- Stabilität (1)
- Stadt (1)
- Stadtmodell (1)
- Stakeholder-based Science (1)
- Stakeholder-basierte Forschung (1)
- Stalagmiten (1)
- Standard deviation (1)
- Start-Up Subsidies (1)
- Start-up Motivation (1)
- Statistical Exercise (1)
- Statistik (1)
- Status und Aufgaben des Verfassungsgerichts (1)
- Steilwinkel-Analyse von PcP (1)
- Stellenbesetzungsrichtlinie (1)
- Stern-Planeten-Wechselwirkung (1)
- Sterne: Entfernungen (1)
- Sternphysik (1)
- Sternwinde (1)
- Stickstoff (1)
- Stiftung (1)
- Stimuli-Sensitivität (1)
- Stochastic Differential Equation (1)
- Stoßwellen (1)
- Strahlungstransport (1)
- Strain Localisation (1)
- Strategie (1)
- Stress response (1)
- Strukturgeologie (1)
- Studienabbruch (1)
- Studieneingang (1)
- Studienerfolg (1)
- Studienqualität (1)
- Studierendenbefragung (1)
- Styrol (1)
- Subduction (1)
- Subduktion (1)
- Subjekttheorie (1)
- Sulfation (1)
- Sun: oszillations (1)
- Sun: sunspots (1)
- Supernovaüberreste (1)
- Survival (1)
- Sway (1)
- Synagogale Musik (1)
- Synagogue music (1)
- Syntaktisches Tagging (1)
- Synthese (1)
- Synthesis (1)
- Systeme interagierender Partikel (1)
- Systems Biology (1)
- TAVI (1)
- TBK1 (1)
- TLR signaling (1)
- TMAO reductase (1)
- TMS (1)
- TRPV1 (1)
- TV Umbau (1)
- Tabak (1)
- Tagung (1)
- TanDEM-X (1)
- Target of Rapamycin kinase (1)
- Tas1r1 (1)
- Tauziehen (1)
- Teacher Education (1)
- Teilhabe (1)
- Tektonik (1)
- Telehealth (1)
- Telemedicine (1)
- Temperaturproxy (1)
- Templatphase (1)
- Tensid (1)
- Theodor W. Adorno (1)
- Thermokarstprozesse (1)
- Thylakoidmembran (1)
- Tibet Plateau (1)
- Tibetan Plateau (1)
- Tiefbeben und Kernexplosionen (1)
- Tiredness (1)
- Tomate (1)
- Tomato (1)
- Tonminerale (1)
- Torsion Experiments (1)
- Torsionsexperimente (1)
- Tourismusmarketing (1)
- Transfer (1)
- Transition (1)
- Transmigration (1)
- Transnationale Migration (1)
- Tree allometry (1)
- Treibhausgasemissionen (1)
- Triazin (1)
- Truppenabzug (1)
- Tsunami (1)
- Turbulenz (1)
- Twitter (1)
- Type 1 diabetes (1)
- Ulmener Maar Tephra (1)
- Ulrich Sonnemann (1)
- Ultra-Niedriggeschwindigkeitszonen (1)
- Umfrage (1)
- Uniform pricing (1)
- Unintended Consequence (1)
- University Presses (1)
- University of Potsdam (1)
- Universität (1)
- Universität Potsdam (1)
- Unsicherheiten (1)
- Unsicherheitsanalyse (1)
- Unterrichtsanalyse (1)
- Unterrichtsmethoden (1)
- Urea-Glas-Route (1)
- Urheberrecht (1)
- VLT/MUSE (1)
- VM (1)
- VM Integration (1)
- VOC (1)
- VR (1)
- Variance (1)
- Vegetation (1)
- Vegetationsmodell (1)
- Verfassungsgericht (1)
- Verfassungsgerichtsbarkeit (1)
- Verfassungsrecht (1)
- Verkürzung (1)
- Versöhnung (1)
- Vertical flux (1)
- Vertical integration (1)
- Vertrauen (1)
- Verwaltungsmodernisierung (1)
- Videoanalyse (1)
- Vignetten (1)
- Virtuelle Maschine (1)
- Vorland (1)
- Vorlandbecken (1)
- Vulkan Verformung (1)
- Vulkanologie (1)
- Vulnerabilität (1)
- Wachstumssignale (1)
- Wandlungsfähigkeit (1)
- Warven (1)
- Warves (1)
- Wasser-Gesteins-Wechselwirkungen (1)
- Wasser/Luft Grenzflächen (1)
- Wasserhaushalt (1)
- Wearable electronic device (1)
- Wearable technology (1)
- Weitwinkelröntgenstreuung (1)
- West-Ost Vergleich (1)
- Westgruppe der Truppen (1)
- Wiedervereinigung (1)
- Windböen (1)
- Winderosion (1)
- Wirkungsforschung (1)
- Wirtschaftsstrafrecht (1)
- Wohlfahrtseffekt (1)
- Wood specific gravity (1)
- Woody aboveground biomass (1)
- Workflow Management System (1)
- Workflow-Management-System (1)
- WorldDEM (1)
- Wärmefluss (1)
- Wärmekapazität (1)
- X-ray (1)
- X-ray diffraction (1)
- Yamal (1)
- Yap1/Wwtr1 (Taz) (1)
- Yiddish (1)
- Ziele (1)
- Zink (1)
- Zirkulardichroismus (1)
- Zyklone (1)
- Züchtung (1)
- [N]phenylene dyads (1)
- [N]phenylenes (1)
- academic teaching (1)
- accelerometer (1)
- acid mine drainage (1)
- acoustic communication (1)
- acoustically levitated droplets (1)
- active galactic nuclei (1)
- actylcholine (1)
- acyclic diene metathesis (ADMET) polymerization (1)
- adaptability (1)
- adaptation (1)
- adaptive management (1)
- addition (1)
- adolescents (1)
- adsorption (1)
- advanced dynamic flow (1)
- aerobic power (1)
- aerosol: hygroscopic growth (1)
- aerosol: hygroskopisches Wachstum (1)
- aerosol: optical properties (1)
- aerosol: optische Eigenschaften (1)
- aggression (1)
- aging (1)
- agricultural landscape (1)
- air pollution (1)
- aktive Galaxienkerne (1)
- akustisch schwebende Tropfen (1)
- allied military liaison missions (1)
- allocation policies (1)
- alpha-2 (1)
- aluminum alloy (1)
- ambient vibration (1)
- ambiguity attitudes (1)
- anaerobe Inkubationensexperimente (1)
- anaerobic incubation experiments (1)
- angle resolved photoelectron spectroscopy (1)
- animal migration (1)
- animal personality (1)
- anisotrop (1)
- anisotropic (1)
- anomalous diffusion (1)
- answer set programming (1)
- anterior cruciate ligament (1)
- anthropology (1)
- anthropometry (1)
- anti-cancer drugs (1)
- antidepressants (1)
- antimicrobial (1)
- apoptosis (1)
- application of artificial intelligence (1)
- approximate methods (1)
- arable weeds (1)
- archetype (1)
- arctic (1)
- arktische Tundra (1)
- arktischer Dunst (1)
- arktisches Aerosol (1)
- artificial intelligence (1)
- assembly factor (1)
- astronomy (1)
- asymptotic method (1)
- athletes (1)
- athletic performance (1)
- atmospheric science (1)
- augmented reality (1)
- automated radio telemetry (1)
- bacteria (1)
- balance (1)
- baroclinicity (1)
- basaltic volcanoes (1)
- basic need satisfaction and frustration (1)
- bats (1)
- behavior problems (1)
- behavioral and self-report measures (1)
- behavioral economics (1)
- behavioral type (1)
- beta-cell (1)
- bibliometric analysis (1)
- bidirectional intracellular transport (1)
- bidirektionaler intrazellulärer Transport (1)
- bild (1)
- binding interactions (1)
- bioconjugate (1)
- biodiversity conservation (1)
- biofilm (1)
- biogenesis (1)
- biography (1)
- biological age (1)
- biology (1)
- biomechanics (1)
- biomolecule (1)
- biorefinery (1)
- birth weight (1)
- bis-MGD (1)
- black holes (1)
- blended learning (1)
- blockchain (1)
- body mass index (1)
- body proportions (1)
- bound phenolic compounds (1)
- boundary layer (1)
- brain health (1)
- breastfeeding (1)
- breeding (1)
- buffer zones (1)
- bulge (1)
- burnout (1)
- business process management (1)
- business processes (1)
- business services (1)
- cTBS (1)
- callous-unemotional traits (1)
- callousness (1)
- camelid antibody (1)
- camelid heavy-chain-only antibodies (1)
- cancer cachexia (1)
- capabilities (1)
- capsule morphology (1)
- carbon cycle (1)
- carbon debt (1)
- carbon emissions (1)
- carbon materials (1)
- carbon nitride (1)
- carbon price (1)
- carbon removal (1)
- cardiac catheterization (CC) (1)
- cardiac development (1)
- cardiology (1)
- cardiomyopathy (1)
- cardiovascular diseases (1)
- cartel (1)
- catch-up-growth (1)
- cathode (1)
- cellular bioenergetics (1)
- cellulose polymeric organic matter (1)
- central Andes (1)
- central and peripheral vision (1)
- central-eastern Beringia (1)
- cereal leaf beetle (1)
- chalcogenide (1)
- change of direction speed (1)
- changepoint analysis (1)
- changepoint detection (1)
- chaperone (1)
- chemokines (1)
- child growth (1)
- children and adolescents (1)
- chimera (1)
- chlorbenzol (1)
- cholesterol (1)
- chronic health condition (1)
- chronic pain (1)
- chronic undernutrition (1)
- chronischer Schmerz (1)
- circular dichroism (1)
- citation analysis (1)
- citrazinic acid (1)
- climate (1)
- climate change adaptation (1)
- climate data (1)
- climate networks (1)
- climate physics (1)
- climate protection (1)
- clinical sample (1)
- clustering (1)
- coating (1)
- coffee processing (1)
- cognition (1)
- cognitive bias (1)
- cognitive/muscular fatigue (1)
- collegial casework (1)
- colloidal quantum dot (1)
- collusion (1)
- color (1)
- communication (1)
- community model (1)
- commuting (1)
- company law (1)
- comparative law (1)
- competencies (1)
- complex emulsion (1)
- complex systems (1)
- computer science education (CSE) (1)
- consolidation (1)
- constitutional law (1)
- consultation (1)
- content knowledge (1)
- continuing education activities (1)
- control loop mechanism (1)
- control resynthesis (1)
- cooperative phenomena (1)
- cooperative transport (1)
- copy number analyses (1)
- copyright law (1)
- core-mantle boundary (1)
- corpus dataset (1)
- cost optimisation (1)
- counting (1)
- coupling (1)
- covalent frameworks (1)
- creativity (1)
- critical collapse (1)
- crops (1)
- cross-species capture (1)
- cultivation (1)
- cyberaggression (1)
- cyclones (1)
- cytokines (1)
- cytosine methylation (1)
- cytosolic tRNA thiolation (1)
- daily home-made measurements (1)
- damage modeling (1)
- damage modelling (1)
- data analysis (1)
- data documentation (1)
- data integration (1)
- data profiling (1)
- data-mining (1)
- debt brake (1)
- decentralization (1)
- decomposition methods (1)
- deep earthquakes and nuclear explosions (1)
- deep eutectic solvents (1)
- deep neural networks (1)
- deferred choice (1)
- definite article (1)
- density-driven flow (1)
- dental eruption (1)
- deoxyfructosazine (1)
- depressive disorder (1)
- depressive symptoms (1)
- design of experiment (1)
- design thinking (1)
- detailed balance equation (1)
- deutsches und russisches Strafrecht (1)
- developing country cities (1)
- development (1)
- diabetes mellitus (1)
- diabetic (1)
- diamond anvil cell (1)
- dichlorbenzol (1)
- dichlorobenzene (1)
- dichtegetriebene Strömung (1)
- dielectrophoresis (1)
- digital technologies (1)
- digital transformation (1)
- diketopiperazine (1)
- disaster risk reduction (1)
- disc (1)
- discipline specific rdm (1)
- discourse comprehension (1)
- discrepancy principle (1)
- discrete choice (1)
- discrimination (1)
- disorder recognition (1)
- distress (1)
- disziplinspezifisches FDM (1)
- diversity (1)
- double dividend (1)
- drought events (1)
- drought intensity (1)
- drought projections (1)
- drug-sensitivity prediction (1)
- dynamical system representation (1)
- dünne Filme (1)
- earth mantle (1)
- eavesdropping (1)
- eccentric-plyometric (1)
- echolocation (1)
- economic impacts (1)
- economy (1)
- ecosystem restoration (1)
- efficiency (1)
- eicosanoids (1)
- elastic coupling (1)
- elastische Kopplung (1)
- elderly (1)
- elevated plus-maze (1)
- elf-determination theory (1)
- embodied cognition (1)
- emergency management (1)
- emergency-aid (1)
- emission line classification (1)
- emotional regulation (1)
- emotional stress (1)
- employment precariousness (1)
- emulsion (1)
- encapsulation (1)
- endocardium (1)
- endophytes (1)
- energy metabolism (1)
- enhancement (1)
- enterprise resource planning systems (1)
- entrepreneurship policy (1)
- environmental pollution (1)
- environmental tax reform (1)
- enzymatically active membrane (1)
- enzyme immobilization (1)
- enzyme/polymer conjugate (1)
- equity crowdfunding (1)
- erythropoiesis (1)
- espionage, Intelligence (1)
- event-related potentials (1)
- everyday life (1)
- exercise cognition (1)
- exercise test (1)
- exercise training (1)
- exoplanet atmospheres (1)
- exoplanets (1)
- expandierbar (1)
- expansion (1)
- external load (1)
- extracellular enzymes (1)
- extremophiles (1)
- eye movements (1)
- fachübergreifend (1)
- family (1)
- fear (1)
- federated learning (1)
- feedback (1)
- feeling of presence (1)
- fence ecology (1)
- ferropericlase (1)
- fiction (1)
- finance (1)
- financial access and inclusion (1)
- finite-size effects (1)
- firn (1)
- first-passage time (1)
- first-reaction time (1)
- fiscal equalization (1)
- fiscal rules (1)
- fissure eruption (1)
- fitness (1)
- flood risk (1)
- floods (1)
- fluorinated polymers (1)
- foam (1)
- food access (1)
- food prices (1)
- food web (1)
- forestry (1)
- formal semantics (1)
- formate assimilation (1)
- forschendes Lernen (1)
- forschungsbasierte Lehre (1)
- foundation (1)
- fractionation (1)
- frailty tool (1)
- frame index (1)
- frames of reference (1)
- frequency analysis (1)
- freshwater (1)
- fruit (1)
- frustration (1)
- functional performance (1)
- functional traits (1)
- fundamental parameters (1)
- fundamentale Parameter (1)
- fungal pathogens (1)
- fungi (1)
- gait (1)
- galactic astronomy (1)
- galaktische Astronomie (1)
- galaxy clusters (1)
- galaxy: general (1)
- games (1)
- gas geochemistry (1)
- gas sorption (1)
- gemeinsame Inversion (1)
- gender pay gap (1)
- general education in computer science (1)
- genome scan (1)
- geodynamics (1)
- geothermal exploration (1)
- geothermal monitoring (1)
- geothermische Exploration (1)
- geothermische Überwachung (1)
- gesture (1)
- glacier forefield (1)
- global labour history (1)
- glucolipotoxicity (1)
- glycan-protein interaction (1)
- glycopolymers (1)
- goal-setting (1)
- goals (1)
- gold (1)
- graduate survey (1)
- grafting-from (1)
- graphs (1)
- grazing (1)
- green chemistry (1)
- gridded data (1)
- ground reaction forces (1)
- group of Soviet forces in Germany (1)
- growth references (1)
- growth standards (1)
- growth tempo (1)
- großräumige Struktur des Universums (1)
- guideline (1)
- gyrochronology (1)
- happiness (1)
- happiness/satisfaction (1)
- hard core potential (1)
- healthcare (1)
- heart rate (1)
- heat capacity (1)
- heat flux (1)
- heavy-chain-only antibody (1)
- height in history (1)
- heliozoa (1)
- heptazine (1)
- herbivory (1)
- heteroatom-doped carbons (1)
- heteroatom-dotierte Kohlenstoffe (1)
- heterogene Katalyse (1)
- heterogeneous catalysis (1)
- hierarchical porosity (1)
- hierarchische Porosität (1)
- high density lipoprotein cholesterol (1)
- high pressure (1)
- high resolution (1)
- high-redshift (1)
- high-sodium (1)
- hippocampal-prefrontal network (1)
- historical growth (1)
- hohe Auflösung (1)
- hoher Rotverschiebung (1)
- home office (1)
- home range (1)
- homologous recombination deficiency (1)
- homology-directed repair (1)
- horizontal equity (1)
- horizontal-vertikales Spektralverhältnis (1)
- horizontaler Fluss (1)
- hospitalization (1)
- host galaxies (1)
- human physical conditioning (1)
- hybridization capture (1)
- hydro-meteorological risk (1)
- hydro-meteorologische Risiken (1)
- hydrodynamic modeling (1)
- hydrodynamische Modellierung (1)
- hyperaccumulation (1)
- hyperspectral remote sensing (1)
- hyperspektral Fernerkundung (1)
- hysteresis (1)
- iPhone (1)
- ice core (1)
- ice sheet (1)
- image (1)
- imaginary world (1)
- imaging spectroscopy (1)
- immunoassay (1)
- impact (1)
- implicit learning (1)
- importin (1)
- in-service training (1)
- inclusive education (1)
- income (1)
- inflammation (1)
- influenza (1)
- informatische Allgemeinbildung (1)
- injury risk (1)
- innovation laboratories (1)
- inquiry (1)
- institutional reform (1)
- instrumental variables (1)
- instrumentation: polarimeters (1)
- instrumentation: spectrographs (1)
- insulin (1)
- insulin resistance (1)
- integration (1)
- integration by parts formula (1)
- intellectual ability (1)
- intelligence (1)
- interacting particle systems (1)
- interdisciplinary (1)
- intergroup contacts (1)
- internal load (1)
- intonation units (1)
- intra-organ-communication (1)
- intracellular transport (1)
- intracluster medium (1)
- intraguild predation (1)
- intrazellulärer Transport (1)
- inversion (1)
- ion mobility spectrometry (1)
- ion-exchange chromatography (1)
- ionothermal synthesis (1)
- isotope variations (1)
- joint inversion (1)
- just transition (1)
- kelp (1)
- key competencies (1)
- kinematics (1)
- knots (1)
- kollegiale Fallbesprechung (1)
- kolloidaler Quantenpunkt (1)
- komplexe Emulsion (1)
- komplexe Systeme (1)
- kooperative Phänomene (1)
- kooperativer Transport (1)
- kovalente Rahmenbedingungen (1)
- kritischer Kollaps (1)
- lab-on-chip (1)
- labor productivity (1)
- labour migration (1)
- lake catchments (1)
- lake sediments (1)
- lakes (1)
- landscape transience (1)
- langreichweitige Korrelationen (1)
- language courses (1)
- language education (1)
- large-scale structure (1)
- lava fountains (1)
- layered compounds (1)
- leadership (1)
- leading cases (1)
- learning through research (1)
- lebende Materialien (1)
- lectins (1)
- legal aspects (1)
- legal history (1)
- leisure time (1)
- light-programmable viscosity (1)
- lignin (1)
- linear enamel hypoplasia (1)
- linear sprint (1)
- linked employer-employee data (1)
- lipid peroxidation (1)
- lipids (1)
- living materials (1)
- locus coeruleus (1)
- logical signaling networks (1)
- logische Signalnetzwerke (1)
- long-memory (1)
- long-range dependence (1)
- low density lipoprotein cholesterol (1)
- low-back-pain (1)
- lubricant (1)
- lysimeter (1)
- ländliche Entwicklung (1)
- ländliche Räume (1)
- lösungsmittelfreie Synthese (1)
- macrostructure (1)
- magnetic fields (1)
- magnetism (1)
- magnetoelasticity (1)
- magnitude estimation (1)
- major depressive disorder (1)
- market-entry game (1)
- markov processes (1)
- maschinelles Lernen (1)
- mass loss (1)
- mass spectrometry (1)
- massereiche Sterne (1)
- massive stars (1)
- math (1)
- mathematical development (1)
- mathematical precursor (1)
- mcgraph (1)
- measurement (1)
- media education (1)
- medical (1)
- medizinisch (1)
- mehrfache Stressfaktoren (1)
- mehrschichtige Verbindungen (1)
- mental imagery (1)
- mental number line (1)
- mental simulation (1)
- mesocrystals (1)
- mesoporous (1)
- mesoporös (1)
- meta-analysis (1)
- meta-science (1)
- metabolic disease (1)
- metabolic engineering (1)
- metabolic genomics (1)
- metabolism (1)
- metabolite breeding (1)
- metabolite profiling (1)
- metabolome (1)
- metadata discovery (1)
- metadata quality (1)
- metathesis (1)
- meteorological drought (1)
- meteorology (1)
- methane cycle (1)
- methanol assimilation (1)
- methods (1)
- miRNAs (1)
- microbial communities (1)
- microbial processes (1)
- microcapsules (1)
- microfacies (1)
- microfluidics (1)
- microplastics (1)
- microplate (1)
- microstructure (1)
- microswimmers (1)
- microwave synthesis (1)
- microzonation (1)
- migrants (1)
- mikrobielle Gemeinschaften (1)
- mikrobielle Prozesse (1)
- mild cognitive impairment (1)
- military history (1)
- mindfulness-based stress reduction (1)
- mini growth spurt (1)
- mining lakes (1)
- mitochondria (1)
- mitochondrial adaptation (1)
- mixture of bridges (1)
- mock data catalogues (1)
- modality (1)
- modifizierte räumliche Autkorrelationsmethode (1)
- molecular biomarkers (1)
- molecular species identification (1)
- molecular weaving (1)
- molekulare Biomarker (1)
- molybdenum cofactor (1)
- monochlorobenzene (1)
- monotone random (1)
- monotonicity conditions (1)
- mortality (1)
- motor-control-exercise (1)
- movement (1)
- multi-valued treatment (1)
- multidisciplinary-therapy (1)
- multiple modalities (1)
- multiple stress factors (1)
- multiresponsiv (1)
- multiresponsive (1)
- muscle metabolism (1)
- muscle strength (1)
- musculoskeletal and neural physiological phenomena (1)
- museum specimens (1)
- music-lesson (1)
- myocardium (1)
- nachhaltige Energiespeichermaterialien (1)
- nanobodies (1)
- nanoelectrodes (1)
- nanoparticle (1)
- nanoparticles (1)
- narrative (1)
- narrative skills (1)
- natural field experiment (1)
- natural language processing (1)
- natural particle (1)
- nature of science (1)
- need profiles (1)
- neovascularization (1)
- net-negative emissions (1)
- network reconstruction (1)
- networks (1)
- neurological disorders (1)
- neuromuscular (1)
- neutralization (1)
- neutron stars (1)
- nichtgenestete Modellselektion (1)
- nicotine (1)
- nitrate (1)
- nitrogen (1)
- noise (1)
- non-Ricardian households (1)
- non-adjacent dependencies (1)
- non-manuals (1)
- non-nested model selection (1)
- nonlinear operator (1)
- nonlinear optics (1)
- novel biomarkers (1)
- nuclear localization signal (1)
- nuclear weapons (1)
- nucleic acids (1)
- number knowledge (1)
- numerical astrophysics (1)
- numerical development (1)
- numerical modelling (1)
- numerical relativity (1)
- numerical skills (1)
- numerische Astrophysik (1)
- numerische Modellierung (1)
- numerische Relativitätstheorie (1)
- nutrition (1)
- nutritional status (1)
- ob/ob (1)
- object search (1)
- offene Daten (1)
- older patients (1)
- oncology (1)
- ontology (1)
- open data (1)
- open-field (1)
- optical properties (1)
- optimal rate (1)
- optische Eigenschaften (1)
- oracles (1)
- organic matter (1)
- organisches Material (1)
- ortsverteile faseroptische Dehnungsmessung (1)
- oscillating bubble (1)
- oxidative stress (1)
- oxygen consumption (1)
- p-type ATPase (1)
- pace of life (1)
- palaeoclimate (1)
- paleoclimate (1)
- paleolimnology (1)
- pandemic (1)
- parentage (1)
- partial ordering (1)
- participation (1)
- past biosphere (1)
- patholinguistics (1)
- peak height velocity (1)
- pedagogical content knowledge (PCK) (1)
- pedagogical reasoning (1)
- peer relations (1)
- peptide biomarkers (1)
- peptide-polymer conjugate (1)
- performance (1)
- performance evaluation (1)
- periglacial landscape evolution (1)
- periglacial landscapes (1)
- periglaziale Landschaften (1)
- periglaziale Landschaftsentwicklung (1)
- periodic entanglement (1)
- permafrost degradation (1)
- permafrost ecosystems (1)
- permafrost sediments (1)
- perovskite (1)
- personal information (1)
- petri net (1)
- philosophy (1)
- phonetics (1)
- phonotaxis (1)
- phosphatidylethanolamine (1)
- phosphatidylserine (1)
- phosphatidylserine decarboxylase (1)
- phospholipids (1)
- phosphoproteomics (1)
- photochemical reactions (1)
- photoinduced electron transfer (1)
- photosystem I (1)
- physical fitness (1)
- physical time (1)
- plant secondary metabolites (1)
- playback (1)
- plyometric exercise (1)
- point-of-care (1)
- policy recommendations (1)
- political opportunism (1)
- politics of production shipyards (1)
- pollution (1)
- polyenoic fatty acids (1)
- polymer network (1)
- polymerization (1)
- polyneuropathy (1)
- population density (1)
- population dynamics (1)
- porous materials (1)
- porous polymers (1)
- poröse Materialien (1)
- poröse Polymere (1)
- possession protection (1)
- post-depositional (1)
- post-natal (1)
- pragmatics (1)
- pre-natal (1)
- pre-service teacher (1)
- precaution (1)
- precuneus (1)
- predictive models (1)
- preschool children (1)
- preschoolers (1)
- prevention (1)
- priming (1)
- privacy and security (1)
- privacy attack (1)
- probabilistic approach (1)
- probabilistischer Ansatz (1)
- problem solving (1)
- productivity slowdown (1)
- professional development (1)
- professional knowledge (1)
- professionalization (1)
- programmable friction (1)
- promises (1)
- propellers (1)
- property taxes (1)
- prosocial (1)
- prosody (1)
- protein (1)
- protein modification (1)
- proteome (1)
- proton conductivity (1)
- proxy uncertainty (1)
- proxy understanding (1)
- psycho-oncology (1)
- psychoeducation (1)
- psychology (1)
- psychopathology (1)
- psychophysiological (1)
- psychotherapy process (1)
- pubertal timing (1)
- public finance (1)
- public good (1)
- public health (1)
- public services (1)
- pupil diameter (1)
- purification (1)
- qualitative research data (1)
- quality (1)
- quasiparticle interactions (1)
- questioning solutions (1)
- radiative transfer (1)
- random sampling (1)
- rational choice (1)
- rdm in disciplines (1)
- reactive transport (1)
- reaktiver Transport (1)
- receptor (1)
- rechtliche Aspekte (1)
- reciprocal processes (1)
- reconciliation (1)
- redistribution (1)
- redox state (1)
- refined consensus model (RCM) (1)
- refugees (1)
- regional autonomy (1)
- regional development (1)
- regional economic effects (1)
- regionalökonomische Effekte (1)
- regularization (1)
- regulation of growth (1)
- reguläre Ausdrücke (1)
- reionization (1)
- relativistic hydrodynamics (1)
- relativistische Hydrodynamik (1)
- remote sensing data (1)
- remote teaching (1)
- removal subsidies (1)
- renewable energy subsidies (1)
- repetition (1)
- representative longitudinal survey data (1)
- representative real-time survey data (1)
- reproductive success (1)
- research data (1)
- research design (1)
- research-based teaching (1)
- resilience (1)
- resistance training (1)
- resource-tracking (1)
- response inhibition (1)
- response styles theory (1)
- response time (1)
- resting-state fMRI (1)
- return level estimation (1)
- return-to-sport (1)
- returns to education (1)
- revenue recycling (1)
- reversed-phase chromatography (1)
- reversible measure (1)
- review (1)
- rheumatic diseases (1)
- rift (1)
- rising bubble (1)
- risk attitudes (1)
- risk management (1)
- ritual (1)
- robustes Parsing (1)
- role-play (1)
- rotation (1)
- rotifer (1)
- rule learning (1)
- rumination (1)
- runners (1)
- running mechanics (1)
- rural (1)
- rural areas (1)
- rural development (1)
- russische Arktis (1)
- räumlich explizit (1)
- räumliche Analyse (1)
- räumliche Autkorrelationsmethode (1)
- räumliche Autokorrelation (1)
- sAA (1)
- salt melt (1)
- salt melt templating (1)
- salt rock (1)
- scene memorization (1)
- scene viewing (1)
- schema discovery (1)
- schwarze Löcher (1)
- science teaching (1)
- sea ice (1)
- secular changes (1)
- sedaDNA (1)
- sedentary (1)
- sediment core (1)
- segmentation (1)
- seismic noise (1)
- seismisches Rauschen (1)
- sekundäre Pflanzenstoffe (1)
- selenite (1)
- selenium (1)
- selenoneine (1)
- self-control (1)
- self-employed (1)
- self-healing coatings (1)
- self-rated health (1)
- seminar concept (1)
- sensitivity (1)
- serial reaction time (SRT) task (1)
- shared leadership (1)
- shell-like geometries (1)
- shipbuildung (1)
- short-term growth (1)
- sign languages (1)
- signal propagation (1)
- signal transition graph (1)
- silica nanoparticles (1)
- simulation (1)
- single case analysis (1)
- single domain antibodies (1)
- single-atom catalysis (1)
- single-case design (1)
- single-case experimental design (1)
- site characterization (1)
- site effects (1)
- skeletal age (1)
- small-angle x-ray scattering (1)
- smart contracts (1)
- social class (1)
- social environment (1)
- social network (1)
- social security system (1)
- social status insecurity (1)
- socialism (1)
- socio-economic effects (1)
- socioeconomy (1)
- sodium-ion batteries (1)
- soft and hard templating (1)
- soft information (1)
- soil (1)
- solitary bees (1)
- soliton (1)
- solvent-free reactions (1)
- sonography (1)
- source model (1)
- source-to-sink (1)
- sozio-ökonomische Effekte (1)
- space-time Gibbs field (1)
- spatial analyses (1)
- spatial frequencies (1)
- spatial language (1)
- spatial updating (1)
- special education (1)
- spectroscopy (1)
- speech (1)
- speech/language therapy (1)
- speed (1)
- speed independent (1)
- spin resolved photoelectron spectroscopy (1)
- spin-orbit coupling (1)
- spinaufgelöste Photoelektronenspektroskopie (1)
- spindown (1)
- spiropyran copolymer (1)
- sport-specific performance (1)
- sports (1)
- stabile Isotope (1)
- stabile Schichtung (1)
- stable stratification (1)
- stag-hunt game (1)
- stalagmites (1)
- standardized patient (1)
- standardized patient information (1)
- standards (1)
- standing long jump (1)
- star-planet interaction (1)
- starch granule (1)
- starch granule morphology (1)
- starch granule size (1)
- starch metabolism (1)
- stark eutektisches Lösungsmittel (1)
- stars: distances (1)
- statistical physics (1)
- statistics (1)
- statistische Physik (1)
- steep-angle analysis of PcP (1)
- steigende Blasen (1)
- stellar content (1)
- stellar physics (1)
- stellar winds (1)
- stellarer Inhalt (1)
- step-growth polymerization (1)
- stimuli-sensitivity (1)
- stochastic bridge (1)
- stochastic resetting (1)
- storm tracks (1)
- strategic-uncertainty attitudes (1)
- stratigraphy (1)
- stress (1)
- stress field (1)
- stress intervention (1)
- stress management (1)
- strike-slip (1)
- striking combat sports (1)
- structural equation model (1)
- structural geology (1)
- student survey (1)
- study designs (1)
- study protocol (1)
- styrene (1)
- subjective survival probability (1)
- subtraction (1)
- sulfite oxidase (1)
- supercritical carbon dioxide (scCO₂) (1)
- supernova remnants (1)
- surface chemistry (1)
- surface modification (1)
- surface processes (1)
- surface rheology (1)
- surface states (1)
- surfactants (1)
- survey (1)
- sustainable energy storage materials (1)
- switchSENSE (1)
- switchSENSE Technologie (1)
- syntax (1)
- systems biology (1)
- tVNS (1)
- taekwondo electronic scoring system (1)
- taekwondo-specific testing (1)
- talk-in-interaction (1)
- tangles (1)
- target capture (1)
- taste receptor (1)
- tax competition (1)
- teacher education (1)
- teacher learning (1)
- teacher quality (1)
- teacher training (1)
- teaching education (1)
- teaching practice (1)
- teaching quality (1)
- tectonics (1)
- temperature proxy (1)
- temperature variability (1)
- template phase (1)
- tendinosis (1)
- terms-of-trade effects (1)
- theory of the subject (1)
- therapist competence (1)
- thermokarst processes (1)
- theta (1)
- thin films (1)
- third-party effect (1)
- thylakoid membranes (1)
- time reversal (1)
- time reversal symmetry (1)
- time-efficient exercise (1)
- tobacco (1)
- topological insulators (1)
- topologische Isolatoren (1)
- toxicity (1)
- trace gas fluxes (1)
- trade (1)
- training (1)
- training adaptation (1)
- transfer (1)
- transformative justice (1)
- transition metals (1)
- transitional justice (1)
- translation (1)
- treatment effects (1)
- treatment integrity (1)
- triazine (1)
- triglycerides (1)
- tug-of-war (1)
- turbulence (1)
- two-dimensional (1)
- type 2 diabetes (1)
- type specimens (1)
- typology (1)
- ultra-low velocity zones (1)
- ultrafast (1)
- ultraschnell (1)
- ultrasound (1)
- umami (1)
- uncaring (1)
- uncertainty (1)
- uncertainty analysis (1)
- unemotional (1)
- unemployment (1)
- ungulate (1)
- unilateral climate policy (1)
- usability (1)
- varves (1)
- vegetation (1)
- vegetation model (1)
- velocity model (1)
- verbal irony (1)
- verbale Ironie (1)
- verfassungsgerichtliche Kontrolle (1)
- vertikaler Fluss (1)
- veterinary cordon fence (1)
- vicious cycle (1)
- video analysis (1)
- vignettes (1)
- virus infection (1)
- vocational education (1)
- voice (1)
- volcanic tremor (1)
- volcano deformation (1)
- volcanology (1)
- voting (1)
- vulkanischer Tremor (1)
- vulnerability (1)
- water balance (1)
- water rock interactions (1)
- water sports (1)
- weak definites (1)
- web-based (1)
- weiche und harte Templatierung (1)
- welfare and gender regimes (1)
- west-east comparison (1)
- western group of forces (1)
- wide-angle x-ray scattering (1)
- wildlife and habitat management (1)
- wind gusts (1)
- winderosion (1)
- winkelaufgelöste Photoelektronenspektroskopie (1)
- withdrawal of troops (1)
- work (1)
- workflow patterns (1)
- working memory (1)
- yellow flags (1)
- youth soccer (1)
- youth sport (1)
- youth sports (1)
- zebrafish (1)
- zentral-östliches Beringia (1)
- zentralen Anden (1)
- zinc (1)
- zweite Ausbildungsphase (1)
- Änderungsanalyse (1)
- Ätna (1)
- Ökologie (1)
- Ökotoxikologie (1)
- Übergangsjustiz (1)
- Übergangsmetalle (1)
- ökonomische Auswirkungen (1)
- überkritisches Kohlendioxid (scCO₂) (1)
- α-amylase/trypsin inhibitors (1)
- „Natur der Naturwissenschaften“ (1)
- social network analysis (1)
- team creativity (1)
- intrapreneurship (1)
Institute
- Extern (478)
- Institut für Biochemie und Biologie (69)
- Institut für Physik und Astronomie (50)
- Institut für Geowissenschaften (40)
- Strukturbereich Kognitionswissenschaften (37)
- Institut für Chemie (33)
- Center for Economic Policy Analysis (CEPA) (28)
- Wirtschaftswissenschaften (28)
- Fachgruppe Volkswirtschaftslehre (26)
- Institut für Ernährungswissenschaft (17)
This thesis covers the synthesis of conjugates of 2-Deoxy-D-ribose-5-phosphate aldolase (DERA) with suitable polymers and the subsequent immobilization of these conjugates in thin films via two different approaches.
2-Deoxy-D-ribose-5-phosphate aldolase (DERA) is a biocatalyst that is capable of converting acetaldehyde and a second aldehyde as acceptor into enantiomerically pure mono- and diyhydroxyaldehydes, which are important structural motifs in a number of pharmaceutically active compounds. Conjugation and immobilization renders the enzyme applicable for utilization in a continuously run biocatalytic process which avoids the common problem of product inhibition. Within this thesis, conjugates of DERA and poly(N-isopropylacrylamide) (PNIPAm) for immobilization via a self-assembly approach were synthesized and isolated, as well as conjugates with poly(N,N-dimethylacrylamide) (PDMAA) for a simplified and scalable spray-coating approach. For the DERA/PNIPAm-conjugates different synthesis routes were tested, including grafting-from and grafting-to, both being common methods for the conjugation. Furthermore, both lysines and cysteines were addressed for the conjugation in order to find optimum conjugation conditions. It turned out that conjugation via lysine causes severe activity loss as one lysine plays a key role in the catalyzing mechanism. The conjugation via the cysteines by a grafting-to approach using pyridyl disulfide (PDS) end-group functionalized polymers led to high conjugation efficiencies in the presence of polymer solubilizing NaSCN. The resulting conjugates maintained enzymatic activity and also gained high acetaldehyde tolerance which is necessary for their use later on in an industrial relevant process after their immobilization.
The resulting DERA/PNIPAm conjugates exhibited enhanced interfacial activity at the air/water interface compared to the single components, which is an important pre-requisite for the immobilization via the self-assembly approach. Conjugates with longer polymer chains formed homogeneous films on silicon wafers and glass slides while the ones with short chains could only form isolated aggregates. On top of that, long chain conjugates showed better activity maintenance upon the immobilization.
The crosslinking of conjugates, as well as their fixation on the support materials, are important for the mechanical stability of the films obtained from the self-assembly process. Therefore, in a second step, we introduced the UV-crosslinkable monomer DMMIBA to the PNIPAm polymers to be used for conjugation. The introduction of DMMIBA reduced the lower critical solution temperature (LCST) of the polymer and thus the water solubility at ambient conditions, resulting in lower conjugation efficiencies and in turn slightly poorer acetaldehyde tolerance of the resulting conjugates. Unlike the DERA/PNIPAm, the conjugates from the copolymer P(NIPAM-co-DMMIBA) formed continuous, homogenous films only after the crosslinking step via UV-treatment. For a firm binding of the crosslinked films, a functionalization protocol for the model support material cyclic olefin copolymer (COC) and the final target support, PAN based membranes, was developed that introduces analogue UV-reactive groups to the support surface. The conjugates immobilized on the modified COC films maintained enzymatic activity and showed good mechanical stability after several cycles of activity assessment. Conjugates with longer polymer chains, however, showed a higher degree of crosslinking after the UV-treatment leading to a pronounced loss of activity. A porous PAN membrane onto which the conjugates were immobilized as well, was finally transferred to a dead end filtration membrane module to catalyze the aldol reaction of the industrially relevant mixture of acetaldehyde and hexanal in a continuous mode. Mono aldol product was detectable, but yields were comparably low and the operational stability needs to be further improved
Another approach towards immobilization of DERA conjugates that was followed, was to generate the conjugates in situ by simply mixing enzyme and polymer and spray coat the mixture onto the membrane support. Compared to the previous approach, the focus was more put on simplicity and a possible scalability of the immobilization. Conjugates were thus only generated in-situ and not further isolated and characterized. For the conjugation, PDMAA equipped with N-2-thiolactone acrylamide (TlaAm) side chains was used, an amine-reactive comonomer that can react with the lysine residues of DERA, as well as with amino groups introduced to a desired support surface. Furthermore disulfide formation after hydrolysis of the Tla groups causes a crosslinking effect. The synthesized copolymer poly(N,N-Dimethylacrylamide-co-N-2-thiolactone acrylamide) (P(DMAA-co-TlaAm)) thus serves a multiple purpose including protein binding, crosslinking and binding to support materials. The mixture of DERA and polymer could be immobilized on the PAN support by spray-coating under partial maintenance of enzymatic activity. To improve the acetaldehyde tolerance, the polymer in used was further equipped with cysteine reactive PDS end-groups that had been used for the conjugation as described in the first part of the thesis. The generated conjugates indeed showed good acetaldehyde tolerance and were thus used to be coated onto PAN membrane supports. Post treatment with a basic aqueous solution of H2O2 was supposed to further crosslink the spray-coated film hydrolysis and oxidation of the thiolactone groups. However, a washing off of the material was observed. Optimization is thus still necessary.
Cardiovascular diseases are the main cause of death worldwide, and their prevalence is expected to rise in the coming years. Polymer-based artificial replacements have been widely used for the treatment of cardiovascular diseases. Coagulation and thrombus formation on the interfaces between the materials and the human physiological environment are key issues leading to the failure of the medical device in clinical implantation. The surface properties of the materials have a strong influence on the protein adsorption and can direct the blood cell adhesion behavior on the interfaces. Furthermore, implant-associated infections will be induced by bacterial adhesion and subsequent biofilm formation at the implantation site. Thus, it is important to improve the hemocompatibility of an implant by altering the surface properties. One of the effective strategies is surface passivation to achieve protein/cell repelling ability to reduce the risk of thrombosis.
This thesis consists of synthesis, functionalization, sterilization, and biological evaluation of bulk poly(glycerol glycidyl ether) (polyGGE), which is a highly crosslinked polyether-based polymer synthesized by cationic ring-opening polymerization. PolyGGE is hypothesized to be able to resist plasma protein adsorption and bacterial adhesion due to analogous chemical structure as polyethylene glycol and hyperbranched polyglycerol. Hydroxyl end groups of polyGGE provide possibilities to be functionalized with sulfates to mimic the anti-thrombogenic function of the endothelial glycocalyx.
PolyGGE was synthesized by polymerization of the commercially available monomer glycerol glycidyl ether, which was characterized as a mixture of mono-, di- and tri-glycidyl ether. Cationic ring opening-polymerization of this monomer was carried out by ultraviolet (UV) initiation of the photo-initiator diphenyliodonium hexafluorophosphate. With the increased UV curing time, more epoxides in the side chains of the monomers participated in chemical crosslinking, resulting in an increase of Young’s modulus, while the value of elongation at break of polyGGE first increased due to the propagation of the polymer chains then decreased with the increase of crosslinking density. Eventually, the chain propagation can be effectively terminated by potassium hydroxide aqueous solution. PolyGGE exhibited different tensile properties in hydrated conditions at body temperature compared to the values in the dry state at room temperature. Both Young’s modulus and values of elongation at break were remarkably reduced when tested in water at 37 °C, which was above the glass transition temperature of polyGGE. At physiological conditions, entanglements of the ployGGE networks unfolded and the free volume of networks were replaced by water molecules as softener, which increased the mobility of the polymer chains, resulting in a lower Young’s modulus.
Protein adsorption analysis was performed on polyGGE films with 30 min UV curing using an enzyme-linked immunosorbent assay. PolyGGE could effectively prevent the adsorption of human plasma fibrinogen, albumin, and fibronectin at the interface of human plasma and polyGGE films. The protein resistance of polyGGE was comparable to the negative controls: the hemocompatible polydimethylsiloxane (PDMS), showing its potential as a coating material for cardiovascular implants. Moreover, antimicrobial tests of bacterial activity using isothermal microcalorimetry and the microscopic image of direct bacteria culturing demonstrated that polyGGE could directly interfere biofilm formation and growth of both Gram-negative and antibiotic-resistant Gram-positive bacteria, indicating the potential application of polyGGE for combating the risk of hospital-acquired infections and preventing drug-resistant superbug spreading.
To investigate its cell compatibility, polyGGE films were extracted by different solvents (ethanol, chloroform, acetone) and cell culture medium. Indirect cytotoxicity tests showed extracted polyGGE films still had toxic effects on L929 fibroblast cells. High-performance liquid chromatography/electrospray ionization mass spectrometry revealed the occurrence of organochlorine-containing compounds released during the polymer-cell culture medium interaction. A constant level of those organochlorine-containing compounds was confirmed from GGE monomer by a specific peak of C-Cl stretching in infrared spectra of GGE. This is assumed to be the main reason causing the increased cell membrane permeability and decreased metabolic activity, leading to cell death. Attempts as changing solvents were made to remove toxic substances, however, the release of these small molecules seems to be sluggish. The densely crosslinked polyGGE networks can possibly contribute to the trapping of organochlorine-containing compounds. These results provide valuable information for exploring the potentially toxic substances, leaching from polyGGE networks, and propose a feasible strategy for minimizing the cytotoxicity via reducing their crosslinking density.
Sulfamic acid/ N-Methyl-2-pyrrolidone (NMP) were selected as the reagents for the sulfation of polyGGE surfaces. Fourier transform attenuated total reflection infrared spectroscopy (ATR-FT-IR) was used to monitor the functionalization kinetics and the results confirmed the successful sulfate grafting on the surface of polyGGE with the covalent bond -C-O-S-. X-ray photoelectron spectroscopy was used to determine the element composition on the surface and the cross-section of the functionalized polyGGE and sulfation within 15 min guarantees the sulfation only takes place on the surface while not occurring in the bulk of the polymer. The concentration of grafted sulfates increased with the increasing reaction time. The hydrophilicity of the surface of polyGGE was highly increased due to the increase of negatively charged end groups. Three sterilization techniques including autoclaving, gamma irradiation, and ethylene oxide (EtO) sterilization were used for polyGGE sulfates. Results from ATR-FT-IR and Toluidine Blue O quantitative assay demonstrated the total loss of the sulfates after autoclave sterilization, which was also confirmed by the increased water contact angle. Little influence on the concentration of sulfates was found for gamma-irradiated and autoclaving sterilized polyGGE sulfates. To investigate the thermal influence on polyGGE sulfates, one strategy was to use poly(hydroxyethyl acrylate) sulfates (PHEAS) for modeling. The thermogravimetric analysis profile of PHEAS demonstrated that sulfates are not thermally stable independent of the substrate materials and decomposition of sulfates occurs at around 100 °C. Although gamma irradiation also showed little negative effect on the sulfate content, the color change in the polyGGE sulfates indicates chemical or physical change might occur in the polymer. EtO sterilization was validated as the most suitable sterilization technique to maintain the chemical structure of polyGGE sulfates.
In conclusion, the conducted work proved that bulk polyGGE can be used as an antifouling coating material and shows its antimicrobial potential. Sulfates functionalization can be effectively realized using sulfamic acid/NMP. EtO sterilization is the most suitable sterilization technique for grafted sulfates. Besides, this thesis also offers a good strategy for the analysis of toxic leachable substances using suitable physicochemical characterization techniques. Future work will focus on minimizing/eliminating the release of toxic substances via reducing the crosslinking density. Another interesting aspect is to study whether grafted sulfates can meet the need for anti-thrombogenicity.
Biofilms are complex living materials that form as bacteria get embedded in a matrix of self-produced protein and polysaccharide fibres. The formation of a network of extracellular biopolymer fibres contributes to the cohesion of the biofilm by promoting cell-cell attachment and by mediating biofilm-substrate interactions. This sessile mode of bacteria growth has been well studied by microbiologists to prevent the detrimental effects of biofilms in medical and industrial settings. Indeed, biofilms are associated with increased antibiotic resistance in bacterial infections, and they can also cause clogging of pipelines or promote bio-corrosion. However, biofilms also gained interest from biophysics due to their ability to form complex morphological patterns during growth. Recently, the emerging field of engineered living materials investigates biofilm mechanical properties at multiple length scales and leverages the tools of synthetic biology to tune the functions of their constitutive biopolymers.
This doctoral thesis aims at clarifying how the morphogenesis of Escherichia coli (E. coli) biofilms is influenced by their growth dynamics and mechanical properties. To address this question, I used methods from cell mechanics and materials science. I first studied how biological activity in biofilms gives rise to non-uniform growth patterns. In a second study, I investigated how E. coli biofilm morphogenesis and its mechanical properties adapt to an environmental stimulus, namely the water content of their substrate. Finally, I estimated how the mechanical properties of E. coli biofilms are altered when the bacteria express different extracellular biopolymers.
On nutritive hydrogels, micron-sized E. coli cells can build centimetre-large biofilms. During this process, bacterial proliferation and matrix production introduce mechanical stresses in the biofilm, which release through the formation of macroscopic wrinkles and delaminated buckles. To relate these biological and mechanical phenomena, I used time-lapse fluorescence imaging to track cell and matrix surface densities through the early and late stages of E. coli biofilm growth. Colocalization of high cell and matrix densities at the periphery precede the onset of mechanical instabilities at this annular region. Early growth is detected at this outer annulus, which was analysed by adding fluorescent microspheres to the bacterial inoculum. But only when high rates of matrix production are present in the biofilm centre, does overall biofilm spreading initiate along the solid-air interface. By tracking larger fluorescent particles for a long time, I could distinguish several kinematic stages of E. coli biofilm expansion and observed a transition from non-linear to linear velocity profiles, which precedes the emergence of wrinkles at the biofilm periphery. Decomposing particle velocities to their radial and circumferential components revealed a last kinematic stage, where biofilm movement is mostly directed towards the radial delaminated buckles, which verticalize. The resulting compressive strains computed in these regions were observed to substantially deform the underlying agar substrates. The co-localization of higher cell and matrix densities towards an annular region and the succession of several kinematic stages are thus expected to promote the emergence of mechanical instabilities at the biofilm periphery. These experimental findings are predicted to advance future modelling approaches of biofilm morphogenesis.
E. coli biofilm morphogenesis is further anticipated to depend on external stimuli from the environment. To clarify how the water could be used to tune biofilm material properties, we quantified E. coli biofilm growth, wrinkling dynamics and rigidity as a function of the water content of the nutritive substrates. Time-lapse microscopy and computational image analysis revealed that substrates with high water content promote biofilm spreading kinetics, while substrates with low water content promote biofilm wrinkling. The wrinkles observed on biofilm cross-sections appeared more bent on substrates with high water content, while they tended to be more vertical on substrates with low water content. Both wet and dry biomass, accumulated over 4 days of culture, were larger in biofilms cultured on substrates with high water content, despite extra porosity within the matrix layer. Finally, the micro-indentation analysis revealed that substrates with low water content supported the formation of stiffer biofilms. This study shows that E. coli biofilms respond to the water content of their substrate, which might be used for tuning their material properties in view of further applications.
Biofilm material properties further depend on the composition and structure of the matrix of extracellular proteins and polysaccharides. In particular, E. coli biofilms were suggested to present tissue-like elasticity due to a dense fibre network consisting of amyloid curli and phosphoethanolamine-modified cellulose. To understand the contribution of these components to the emergent mechanical properties of E. coli biofilms, we performed micro-indentation on biofilms grown from bacteria of several strains. Besides showing higher dry masses, larger spreading diameters and slightly reduced water contents, biofilms expressing both main matrix components also presented high rigidities in the range of several hundred kPa, similar to biofilms containing only curli fibres. In contrast, a lack of amyloid curli fibres provides much higher adhesive energies and more viscoelastic fluid-like material behaviour. Therefore, the combination of amyloid curli and phosphoethanolamine-modified cellulose fibres implies the formation of a composite material whereby the amyloid curli fibres provide rigidity to E. coli biofilms, whereas the phosphoethanolamine-modified cellulose rather acts as a glue. These findings motivate further studies involving purified versions of these protein and polysaccharide components to better understand how their interactions benefit biofilm functions.
All three studies depict different aspects of biofilm morphogenesis, which are interrelated. The first work reveals the correlation between non-uniform biological activities and the emergence of mechanical instabilities in the biofilm. The second work acknowledges the adaptive nature of E. coli biofilm morphogenesis and its mechanical properties to an environmental stimulus, namely water. Finally, the last study reveals the complementary role of the individual matrix components in the formation of a stable biofilm material, which not only forms complex morphologies but also functions as a protective shield for the bacteria it contains. Our experimental findings on E. coli biofilm morphogenesis and their mechanical properties can have further implications for fundamental and applied biofilm research fields.
In dieser Arbeit wird den verschiedenen Thesen, die das Wahlverhalten in Ostdeutschland begründen, nachgegangen. Der Einbezug der politischen Kultur scheint als Erweiterung des sozialpsychologischen Ansatzes notwendig, um das Wählerverhalten in den neuen Bundesländern angemessen zu modellieren. Für die Analyse der Parteiaffinitäten werden die in den ersten beiden Kapiteln ausgearbeiteten Deutungen zu empirisch überprüfbaren Hypothesen verdichtet und anhand der im empirischen Teil der Arbeit aufgestellten Regressionsmodelle getestet. Inhalt: Die politische Kultur in Ostdeutschland - Besonderheiten politischer Einstellungen: Einstellungen zur Demokratie, Identitätsabgrenzung - Problemwahrnehmungen und Kompetenzzuweisungen Ostdeutsches Wahlverhalten - Thesen - Politisierung der Sozialstruktur - Anwendbarkeit des Konzeptes Parteiidentifikation - Parteiidentifikation und Sozialstruktur - Sachthemen und Kandidaten Empirischer Test - Daten und Methode: Kausalmodell - Hypothesen - Ergebnisse für die einzelnen Parteien: CDU, SPD, PDS - Relatives Gewicht lang- und kurzfristiger Faktoren Fazit - Diskussion der Ergebnisse
Privacy regulations and the physical distribution of heterogeneous data are often primary concerns for the development of deep learning models in a medical context. This paper evaluates the feasibility of differentially private federated learning for chest X-ray classification as a defense against data privacy attacks. To the best of our knowledge, we are the first to directly compare the impact of differentially private training on two different neural network architectures, DenseNet121 and ResNet50. Extending the federated learning environments previously analyzed in terms of privacy, we simulated a heterogeneous and imbalanced federated setting by distributing images from the public CheXpert and Mendeley chest X-ray datasets unevenly among 36 clients. Both non-private baseline models achieved an area under the receiver operating characteristic curve (AUC) of 0.940.94 on the binary classification task of detecting the presence of a medical finding. We demonstrate that both model architectures are vulnerable to privacy violation by applying image reconstruction attacks to local model updates from individual clients. The attack was particularly successful during later training stages. To mitigate the risk of a privacy breach, we integrated Rényi differential privacy with a Gaussian noise mechanism into local model training. We evaluate model performance and attack vulnerability for privacy budgets ε∈{1,3,6,10}�∈{1,3,6,10}. The DenseNet121 achieved the best utility-privacy trade-off with an AUC of 0.940.94 for ε=6�=6. Model performance deteriorated slightly for individual clients compared to the non-private baseline. The ResNet50 only reached an AUC of 0.760.76 in the same privacy setting. Its performance was inferior to that of the DenseNet121 for all considered privacy constraints, suggesting that the DenseNet121 architecture is more robust to differentially private training.
Models are useful tools for understanding and predicting ecological patterns and processes. Under ongoing climate and biodiversity change, they can greatly facilitate decision-making in conservation and restoration and help designing adequate management strategies for an uncertain future. Here, we review the use of spatially explicit models for decision support and to identify key gaps in current modelling in conservation and restoration. Of 650 reviewed publications, 217 publications had a clear management application and were included in our quantitative analyses. Overall, modelling studies were biased towards static models (79%), towards the species and population level (80%) and towards conservation (rather than restoration) applications (71%). Correlative niche models were the most widely used model type. Dynamic models as well as the gene-to-individual level and the community-to-ecosystem level were underrepresented, and explicit cost optimisation approaches were only used in 10% of the studies. We present a new model typology for selecting models for animal conservation and restoration, characterising model types according to organisational levels, biological processes of interest and desired management applications. This typology will help to more closely link models to management goals. Additionally, future efforts need to overcome important challenges related to data integration, model integration and decision-making. We conclude with five key recommendations, suggesting that wider usage of spatially explicit models for decision support can be achieved by 1) developing a toolbox with multiple, easier-to-use methods, 2) improving calibration and validation of dynamic modelling approaches and 3) developing best-practise guidelines for applying these models. Further, more robust decision-making can be achieved by 4) combining multiple modelling approaches to assess uncertainty, and 5) placing models at the core of adaptive management. These efforts must be accompanied by long-term funding for modelling and monitoring, and improved communication between research and practise to ensure optimal conservation and restoration outcomes.
The increasing development of antibiotic resistance in bacteria has been a major problem for years, both in human and veterinary medicine. Prophylactic measures, such as the use of vaccines, are of great importance in reducing the use of antibiotics in livestock. These vaccines are mainly produced based on formaldehyde inactivation. However, the latter damages the recognition elements of the bacterial proteins and thus could reduce the immune response in the animal. An alternative inactivation method developed in this work is based on gentle photodynamic inactivation using carbon nanodots (CNDs) at excitation wavelengths λex > 290 nm. The photodynamic inactivation was characterized on the nonvirulent laboratory strain Escherichia coli K12 using synthesized CNDs. For a gentle inactivation, the CNDs must be absorbed into the cytoplasm of the E. coli cell. Thus, the inactivation through photoinduced formation of reactive oxygen species only takes place inside the bacterium, which means that the outer membrane is neither damaged nor altered. The loading of the CNDs into E. coli was examined using fluorescence microscopy. Complete loading of the bacterial cells could be achieved in less than 10 min. These studies revealed a reversible uptake process allowing the recovery and reuse of the CNDs after irradiation and before the administration of the vaccine. The success of photodynamic inactivation was verified by viability assays on agar. In a homemade flow photoreactor, the fastest successful irradiation of the bacteria could be carried out in 34 s. Therefore, the photodynamic inactivation based on CNDs is very effective. The membrane integrity of the bacteria after irradiation was verified by slide agglutination and atomic force microscopy. The method developed for the laboratory strain E. coli K12 could then be successfully applied to the important avian pathogens Bordetella avium and Ornithobacterium rhinotracheale to aid the development of novel vaccines.
The large literature that aims to find evidence of climate migration delivers mixed findings. This meta-regression analysis i) summarizes direct links between adverse climatic events and migration, ii) maps patterns of climate migration, and iii) explains the variation in outcomes. Using a set of limited dependent variable models, we meta-analyze thus-far the most comprehensive sample of 3,625 estimates from 116 original studies and produce novel insights on climate migration. We find that extremely high temperatures and drying conditions increase migration. We do not find a significant effect of sudden-onset events. Climate migration is most likely to emerge due to contemporaneous events, to originate in rural areas and to take place in middle-income countries, internally, to cities. The likelihood to become trapped in affected areas is higher for women and in low-income countries, particularly in Africa. We uniquely quantify how pitfalls typical for the broader empirical climate impact literature affect climate migration findings. We also find evidence of different publication biases.
Interdisciplinary studies on information structure : ISIS ; working papers of the SFB 632. - Vol. 1
(2004)
Contents: A1: Phonology and syntax of focussing and topicalisation: Gisbert Fanselow: Cyclic Phonology–Syntax-Interaction: Movement to First Position in German Caroline Féry and Laura Herbst: German Sentence Accent Revisited Shinichiro Ishihara: Prosody by Phase: Evidence from Focus Intonation–Wh-scope Correspondence in Japanese A2: Quantification and information structure: Cornelia Endriss and Stefan Hinterwimmer: The Influence of Tense in Adverbial Quantification A3: Rhetorical Structure in Spoken Language: Modeling of Global Prosodic Parameters: Ekaterina Jasinskaja, Jörg Mayer and David Schlangen: Discourse Structure and Information Structure: Interfaces and Prosodic Realization B2: Focussing in African Tchadic languages: Katharina Hartmann and Malte Zimmermann: Focus Strategies in Chadic: The Case of Tangale Revisited D1: Linguistic database for information structure: Annotation and retrieval: Stefanie Dipper, Michael Götze, Manfred Stede and Tillmann Wegst: ANNIS: A Linguistic Database for Exploring Information Structure
The papers in this volume were presented at the workshop Heterogeneity in Linguistic Databases', which took place on July 9, 2004 at the University of Potsdam. The workshop was organized by project D1: Linguistic Database for Information Structure: Annotation and Retrieval', a member project of the SFB 632, a collaborative research center entitled Information Structure: the Linguistic Means for Structuring Utterances, Sentences and Texts'. The workshop brought together both developers and users of linguistic databases from a number of research projects which work on an empirical basis, all of which have to cope with different sorts of heterogeneity: primary linguistic data and annotated information may be heterogeneous, as well as the data structures representing them. The first four papers (by Wagner, Schmidt, Lüdeling, and Witt) address aspects of heterogeneous data from the point of view of database developers; the remaining three papers (by Meyer, Smith, and Teich/Fankhauser) focus on data exploitation by the users.
Inhalt: Ulrike Franke, Gabriele Krätzer: Das Leitbild der Stadtentwicklung in Potsdam und die Bedeutung des Handels für die Stadtentwicklung Silvana Wagenitz: Rahmenbedingungen des Handels in und um Potsdam Torben Roffka: Vorhandene Handelsstrukturen und geplante Handelsprojekte in und um Potsdam Gesine Schmeichel: Perspektiven der Potsdamer Stadt- und Handelsentwicklung : Szenarien der Handelsentwicklung in Potsdam Cindy Kramer, Elke Radke: Perspektiven der Potsdamer Stadt- und Handelsentwicklung : Maßnahmen zur Steigerung der Attraktivität des inner- und außerstädtischen Handels in Potsdam
Dieser vorliegende Lehr- und Forschungsbericht des Lehrstuhls für Betriebswirtschaftslehre mit dem Schwerpunkt Marketing beschreibt ausgewählte Ergebnisse einer empirischen Studie zum Kulturmarketing. Inhalt: Erhebungssteckbrief Ziel der Studie und methodisches Vorgehen Erhebungsdesign und Stichprobenstruktur - Vorgehen bei der Erhebung - Probleme bei der Durchführung der Interviews - Stichprobenstruktur - Eine Analyse der Besucherstrukturen der Potsdamer Arkadien und konkurrierender Kulturveranstaltungen Marktanalyse des Kulturangebots in Potsdam - Beschreibung der Wettbewerbssituation des Potsdamer Kulturangebots - Positionierung der Potsdamer Arkadien und anderer Kulturveranstaltungen aus Sicht der Veranstalter Darstellung der Ergebnisse - Bekanntheit der Potsdamer Arkadien - Das Entscheidungs- und Nutzungsverhalten von Besuchern der Potsdamer Arkadien und Besuchern konkurrierender Kulturveranstaltungen - Das lnformationsverhalten von Besuchern der Potsdamer Arkadien - Stärken und Schwächen der Potsdamer Arkadien - Verbesserungsvorschläge - Zufriedenheit mit den Potsdamer Arkadien aus Sicht der Besucher - Zahlungsbereitschaftsanalyse von Besuchern der Potsdamer Arkadien - Erwartungen an Kulturveranstaltungen und Gründe für den Besuch der Potsdamer Arkadien - Einstellungen zu den Potsdamer Arkadien: Wichtigkeit und Bewertung von ausgewählten Merkmalen der Potsdamer Arkadien - Die Stadt Potsdam in der Wahrnehmung ihrer Bürger: Ermittlung des Wahrnehmungsraumes von Kulturveranstaltungen mittels der Korrespondenzanalyse - Typologisierung der Befragten nach ihren kulturellen Werteorientierungen
Die vorliegende Festschrift wird Frau Prof. Gabrielle Saupe anlässlich ihrer Verabschiedung aus dem Institut für Geographie der Universität Potsdam gewidmet. Bewegende Räume - damit sind emotionale, materielle und strukturelle Bewegungen in einem räumlichen Kontext gemeint. Die Vieldeutigkeit des Titels impliziert die Vielfalt der wissenschaftlichen Auseinandersetzung mit dem Raum. Ein illustres Autorenkollektiv deutscher Raumwissenschaftler verdeutlicht anhand von verschiedenen zum Teil essayartigen Artikeln sein Verständnis von Raum. Die interdisziplinäre Konzeption des Heftes soll das ständige Bemühen von Frau Saupe verdeutlichen, verschiedene Perspektiven, Herangehensweisen und Fachdisziplinen zur Bewältigung der Forschungsaufgaben zusammenzuführen. Hierbei sind die wichtigsten Forschungsprojekte von Frau Saupe ebenso vertreten wie einige der von ihr betreuten Qualifikationsarbeiten. Die Beiträge reichen von der Landschafts- bzw. Geoökologie bis zum Fußball und der Musik. Sie spannen einen Bogen von der Geographie als Regionalwissenschaft zu modernen stadtsoziologischen Fragestellungen, stellen Ergebnisse neuerer Forschungsprojekte vor und widmen sich der Entwicklung von nahen und fernen Räumen aus verschiedenen Perspektiven.
Die vorliegende Untersuchung basiert auf einer Befragung von insgesamt 93 Unternehmen aus den Regionen Potsdam, Berlin und Chemnitz. Die Interviews wurden im Zeitraum Mai/Juni 1996 durchgeführt und dauerten ca. 1 Stunde. Im Mittelpunkt der Befragung standen die Themenbereiche: ökologische Betroffenheit, Einstellung zum Umweltschutz, Markt- und Wettbewerbsbedingungen des betrieblichen Umweltschutzes, Umfang und Intensität betrieblicher Maßnahmen zum Umweltschutz sowie Verhaltensbarrieren. Als Interviewpartner standen in der Mehrzahl der befragten Unternehmen die Geschäftsführer oder Umweltbeauftragte bzw. andere Personen in Führungspositionen zur Verfügung. Zum überwiegenden Teil waren die von uns befragten Unternehmer selbst Eigentümer der Unternehmung. Die befragten Unternehmen gehören überwiegend dem Konsumgütersektor (44%) an. Ein Drittel der Unternehmen stammt aus dem Investitionsgütersektor (33%). Der Dienstleistungssektor ist mit lediglich 23% in der Stichprobe vertreten. Insgesamt bildet die Stichprobe ein breites Branchenspektrum ab, wenn auch die Geschäftsbereiche Maschinenbau und Anlagen, bedingt durch ihre starke Präsenz im Raum Chemnitz, deutlich überrepräsentiert sind. Hinsichtlich der Beschäftigtenzahlen und Umsätze handelt es sich in der Befragung überwiegend um kleine und mittelständische Betriebe, wiewohl auch einige größere Unternehmen berücksichtigt wurden.
Dieser erste Lehr- und Forschungsbericht des Lehrstuhls für Betriebswirtschaftslehre mit dem Schwerpunkt Marketing beschreibt, analysiert und interpretiert ausgewählte Ergebnisse einer empirischen Studie zum lmage Potsdams bei lokalen Unternehmern. Inhalt: Die Studie im Überblick: Erhebungssteckbrief, Zusammenfassung der wichtigsten Ergebnisse Ziel der Studie Erhebungsdesign und Struktur der Stichprobe Das Image Potsdams als Wirtschaftsstandort - Die Standortfaktoren - Die Einschätzung der Standortfaktoren: Das Überzeugungsprofil - Die Wichtigkeit der Standortfaktoren: Das Anforderungsprofil - Die Stärken und Schwächen Potsdams als Wirtschaftsstandort Typologisierung der lokalen Unternehmer nach ihrem lmage vom Wirtschaftsstandort Potsdam Das lmage Potsdams als Lebensraum für Unternehmer - Das lmageprofil der Stadt Potsdam als Lebensraum - Das 'Innere Bild' von der Stadt Potsdam Die wirtschaftliche Zukunft von Potsdam aus der Sicht der befragten Unternehmer Konsequenzen und Ansatzpunkte für die Gestaltung eines effizienten Regionalen Marketingkonzepts
In der brandenburgischen Landesverwaltung und Justiz sollen in den nächsten Jahren noch ca. 8.000 Stellen eingespart werden. Gleichzeitig sind die Landesverwaltung und die Justiz an die demografische Entwicklung und die damit verbundenen Aufgabenveränderungen anzupassen. Das ressortübergreifende Personalmanagement gewinnt hierdurch an Bedeutung. Um den Prozess zu gestalten, hat die Landesregierung eine Besetzungsrichtlinie erlassen und mit den Gewerkschaften einen Tarifvertrag zum Verwaltungsumbau (TV Umbau) abgeschlossen, die in diesem Band ebenso abgedruckt sind, wie die Durchführungshinweise des Ministeriums des Innern. Darüber hinaus enthält der Band die aktuell geltende Personalbedarfsplanung bis Ende 2015, die Dr. Folke Schneider erläutert. In einem Beitrag von Volker-Gerd Westphal wird eine Gesamtschau der Rahmenbedingungen für das Personalmanagement in der brandenburgischen Landesverwaltung und Justiz vorgenommen.
Permettez à l’inventeur du manuscrit dont vous avez l’édition diplomatique sous les yeux d’exposer en exergue les principales étapes qui ont conduit en 2012 à la détermination de la langue et à l’identification de l’auteur.
Étant inscrit à la conférence de linguistique missionnaire à l’université de Brème en mars 2012 et conscient que maintes bibliothèques et archives renferment des trésors non identifiés ou mal catalogués, je suivis le conseil d’un collègue de la bibliothèque de l’université de Trèves, Hans-Ulrich Seiffert, d’inspecter le manuscrit 1136 / 2048 4° de la bibliothèque municipale de Trèves. Cette bibliothèque est riche de plus de 2.500 manuscrits et incunables provenant pour la plupart des saisies révolutionnaires françaises dans les bibliothèques des ci-devant couvents trévirois. Parmi ces trésors un manuscrit portugais des missions qui était rentré dans les fonds de la bibliothèque de Trèves dès 1799 et avait été exposé en 1991 dans le cadre d’une évocation des activités missionnaires globales des Jésuites. Michael Embach, alors directeur de la bibliothèque du séminaire épiscopal de Trèves, l’avait brièvement décrit dans une notice qui prétendait qu’il était rédigé en espagnol et en portugais et avait peut-être été composé par un auteur « Meirin » dans le cadre de ses préparations pour partir dans les missions… Dans ma copie du catalogue de 1991 se trouve inscrit « la langue reste à déterminer ».
J’allais résoudre le mystère en cette mémorable journée du jeudi 23 février 2012 quand je me résolus à l’autopsier dans la salle désormais historique de la Bibliothèque municipale de Trèves, dirigée depuis peu par le collègue Embach. Il parut à l’évidence que le manuscrit ne contenait aucun mot d’espagnol mais que dans la première partie, les entrées en portugais, strictement numérotées et arrangées dans l’ordre alphabétique, étaient suivies par leurs équivalences dans une langue inconnue qui, cependant, avait pour un linguiste une forte odeur de l’Amérique amazonienne. La partie postérieure du manuscrit présentait l’arrangement inverse. Les entrées dans la langue inconnue étaient suivies de leurs équivalences portugaises. Ce n’est que plus tard que nous avons compris le mystérieux ordre des lemmata dans cette partie, basée qu’elle est sur la rime finale des mots.
Deux facteurs ont grandement facilité l’identification de la langue inconnue : 1. la permission du directeur Embach de pouvoir prendre des photos de travail de tous les folios du manuscrit et 2. l’entrée dans le premier catalogue de la Bibliothèque de Trèves de 1802 : “Codex maxime memorabiblis est, cum nondum grammatica praeter Lusitani Anchieta nota sit, et nullum vocabularium huius linguae existet. Sine dubio scriptum est a quodam Missionario Jesuita”.
Rentrant de Trèves chez moi, je fis une brève halte dans mon bureau d’alors pour consulter Internet. L’entrée “Anchieta” dans l’encyclopédie électronique Wikipedia m’informait que ce jésuite portugais avait composé une grammaire du Vieux Tupi, publiée en 1595. Sous le vocable “Old Tupi” ensuite, j’appris que l’auto-désignation pour cette langue est ñeengatú (la bonne langue, le parler correct). De là à retrouver au folio 25 de mes photos la traduction du portugais linguagem par nheénga ne prit que quelques minutes. Dès ce premier soir donc, le mystère de la langue inconnue était résolu!
Un projet de recherche international, voire transcontinental allait se mettre peu à peu en place après. À la conférence de Brème, début mars 2012, je fis la connaissance du linguiste et romaniste, le professeur Wolf Dietrich de l’université de Münster en Westphalie, un des meilleurs connaisseurs des parlers amazoniens. Il rentrait avec une copie de mes photos de travail et confirma bientôt l’importance du manuscrit de Trèves pour la connaissance de la Lingua Geral, le parler qui s’était développé à partir du Vieux Tupi moribond.
Je communiquai également ma découverte au frère Karl-Heinz Arenz de la congrégation des pères de Steyl, originaire de l’Eifel allemande et enseignant d’histoire aux universités brésiliennes de Belém et de Santarém dans l’État du Pará. Arenz est l’auteur d’une étude sur le jésuite luxembourgeois Jean-Philippe Bettendorf, actif au Maranhão dans la seconde moitié du XVIIe siècle. Nous avions collaboré en 2007 à une exposition didactique consacrée à ce personnage. Arenz ne tarda pas à passer l’information sur le manuscrit de Trèves aux deux linguistes brésiliennes Cândida Barros et Ruth Monserrat, qui à leur tour présentaient un projet de recherche qui fut accepté par les autorités brésiliennes. Les reals de ce subside furent bien investis en effet : l’étudiant doctoral Gabriel Prudente réalisa une transcription intégrale du manuscrit de Trèves qui fit apparaître des couches dialectales et sociolectales dans le texte, et même quelques mots allemands. La bibliothèque municipale de Trèves, quant à elle, contribua « en nature » les images digitales qui sont consultables sur les pages de gauche de cette édition électronique.
Début avril 2014, nous fîmes tous connaissance personnellement dans le cadre d’un colloque à l’université de Belém où fut décidée la présente édition digitale et où furent prononcées la plupart des contributions scientifiques que vous pouvez lire en guise d’introduction. Restait à percer l’énigme du véritable auteur du manuscrit. Cândida Barros avait assez tôt proposé les noms de trois Jésuites allemands, actifs dans les années 1750 dans la région du fleuve Xingu et chassés par les mesures anti-jésuites du pouvoir portugais en 1756. L’étude paléographique des Quattuor vota des trois candidats, aux archives centrales des Jésuites à Rome, me permit début septembre 2015 d’éliminer les pères Eckart et Kaulen et de ne retenir que Antonius Meisterburg, originaire de Bernkastel sur la Moselle, comme le scribe du manuscrit de Trèves. Qu’il me soit permis d’exprimer ma GRATITUDE à toutes celles et à tous ceux qui ont contribué à cette belle aventure de découverte intellectuelle et scientifique et à rendre au Brésil une petite pierre de son histoire.
Stellar winds play an important role for the evolution of massive stars and their cosmic environment. Multiple lines of evidence, coming from spectroscopy, polarimetry, variability, stellar ejecta, and hydrodynamic modeling, suggest that stellar winds are non-stationary and inhomogeneous. This is referred to as 'wind clumping'. The urgent need to understand this phenomenon is boosted by its far-reaching implications. Most importantly, all techniques to derive empirical mass-loss rates are more or less corrupted by wind clumping. Consequently, mass-loss rates are extremely uncertain. Within their range of uncertainty, completely different scenarios for the evolution of massive stars are obtained. Settling these questions for Galactic OB, LBV and Wolf-Rayet stars is prerequisite to understanding stellar clusters and galaxies, or predicting the properties of first-generation stars. In order to develop a consistent picture and understanding of clumped stellar winds, an international workshop on 'Clumping in Hot Star Winds' was held in Potsdam, Germany, from 18. - 22. June 2007. About 60 participants, comprising almost all leading experts in the field, gathered for one week of extensive exchange and discussion. The Scientific Organizing Committee (SOC) included John Brown (Glasgow), Joseph Cassinelli (Madison), Paul Crowther (Sheffield), Alex Fullerton (Baltimore), Wolf-Rainer Hamann (Potsdam, chair), Anthony Moffat (Montreal), Stan Owocki (Newark), and Joachim Puls (Munich). These proceedings contain the invited and contributed talks presented at the workshop, and document the extensive discussions.