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Driven polymer translocation into a channel: Isoflux tension propagation theory and Langevin dynamics simulations

  • Isoflux tension propagation (IFTP) theory and Langevin dynamics (LD) simulations are employed to study the dynamics of channel-driven polymer translocation in which a polymer translocates into a narrow channel and the monomers in the channel experience a driving force fc. In the high driving force limit, regardless of the channel width, IFTP theory predicts τ ∝ f βc for the translocation time, where β = −1 is the force scaling exponent. Moreover, LD data show that for a very narrow channel fitting only a single file of monomers, the entropic force due to the subchain inside the channel does not play a significant role in the translocation dynamics and the force exponent β = −1 regardless of the force magnitude. As the channel width increases the number of possible spatial configurations of the subchain inside the channel becomes significant and the resulting entropic force causes the force exponent to drop below unity.

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Metadaten
Author details:Jalal SarabadaniORCiD, Ralf MetzlerORCiDGND, Tapio Ala-NissilaORCiD
DOI:https://doi.org/10.1103/PhysRevResearch.4.033003
ISSN:2643-1564
Title of parent work (English):Physical Review Research
Publisher:American Physical Society
Place of publishing:College Park, Maryland, USA
Publication type:Article
Language:English
Date of first publication:2022/07/01
Publication year:2022
Release date:2023/01/10
Volume:4
Article number:033003
Print run:3
Number of pages:14
First page:033003-1
Last Page:033003-14
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Physik und Astronomie
Extern / Extern
DDC classification:5 Naturwissenschaften und Mathematik / 53 Physik / 530 Physik
Peer review:Referiert
Grantor:Publikationsfonds der Universität Potsdam
Publishing method:Open Access / Gold Open-Access
License (German):License LogoCC-BY - Namensnennung 4.0 International
External remark:Zweitveröffentlichung in der Schriftenreihe Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe ; 1292
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