Raman enhancement of nanoparticle dimers self-assembled using DNA origami nanotriangles
- Surface-enhanced Raman scattering is a powerful approach to detect molecules at very low concentrations, even up to the single-molecule level. One important aspect of the materials used in such a technique is how much the signal is intensified, quantified by the enhancement factor (EF). Herein we obtained the EFs for gold nanoparticle dimers of 60 and 80 nm diameter, respectively, self-assembled using DNA origami nanotriangles. Cy5 and TAMRA were used as surface-enhanced Raman scattering (SERS) probes, which enable the observation of individual nanoparticles and dimers. EF distributions are determined at four distinct wavelengths based on the measurements of around 1000 individual dimer structures. The obtained results show that the EFs for the dimeric assemblies follow a log-normal distribution and are in the range of 10(6) at 633 nm and that the contribution of the molecular resonance effect to the EF is around 2, also showing that the plasmonic resonance is the main source of the observed signal. To support our studies, FDTDSurface-enhanced Raman scattering is a powerful approach to detect molecules at very low concentrations, even up to the single-molecule level. One important aspect of the materials used in such a technique is how much the signal is intensified, quantified by the enhancement factor (EF). Herein we obtained the EFs for gold nanoparticle dimers of 60 and 80 nm diameter, respectively, self-assembled using DNA origami nanotriangles. Cy5 and TAMRA were used as surface-enhanced Raman scattering (SERS) probes, which enable the observation of individual nanoparticles and dimers. EF distributions are determined at four distinct wavelengths based on the measurements of around 1000 individual dimer structures. The obtained results show that the EFs for the dimeric assemblies follow a log-normal distribution and are in the range of 10(6) at 633 nm and that the contribution of the molecular resonance effect to the EF is around 2, also showing that the plasmonic resonance is the main source of the observed signal. To support our studies, FDTD simulations of the nanoparticle's electromagnetic field enhancement has been carried out, as well as calculations of the resonance Raman spectra of the dyes using DFT. We observe a very close agreement between the experimental EF distribution and the simulated values.…
Verfasserangaben: | Sergio Kogikoski JuniorORCiD, Kosti TapioORCiD, Robert Edler von Zander, Peter SaalfrankORCiDGND, Ilko BaldORCiDGND |
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DOI: | https://doi.org/10.3390/molecules26061684 |
ISSN: | 1420-3049 |
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/33802892 |
Titel des übergeordneten Werks (Englisch): | Molecules : a journal of synthetic chemistry and natural product chemistry / Molecular Diversity Preservation International |
Verlag: | MDPI |
Verlagsort: | Basel |
Publikationstyp: | Wissenschaftlicher Artikel |
Sprache: | Englisch |
Datum der Erstveröffentlichung: | 17.03.2021 |
Erscheinungsjahr: | 2021 |
Datum der Freischaltung: | 12.10.2023 |
Freies Schlagwort / Tag: | DNA origami; nanoparticle dimers; resonance Raman; scattering; surface-enhanced Raman scattering |
Band: | 26 |
Ausgabe: | 6 |
Aufsatznummer: | 1684 |
Seitenanzahl: | 18 |
Fördernde Institution: | Sao Paulo Research Foundation (FAPESP fellowships), BrazilFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2016/14507-8, 2018/17831-6]; European Research Council (ERC)European Research Council (ERC)European Commission [772752]; Fraunhofer High-Performance Center for Functional lntegration in Materials; German Federal Ministry of Education and ResearchFederal Ministry of Education & Research (BMBF) [03Z22A512]; Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence StrategyGerman Research Foundation (DFG) [EXC 2008/1-390540038] |
Organisationseinheiten: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
DDC-Klassifikation: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Peer Review: | Referiert |
Publikationsweg: | Open Access / Gold Open-Access |
DOAJ gelistet | |
Lizenz (Deutsch): | CC-BY - Namensnennung 4.0 International |