Genomic analysis of three Clostridioides difficile isolates from urban water sources

We investigated inflow of a wastewater treatment plant and sediment of an urban lake for the presence of Clostridioides difficile by cultivation and PCR. Among seven colonies we sequenced the complete genomes of three: two non-toxigenic isolates from wastewater and one toxigenic isolate from the urban lake. For all obtained isolates, a close genomic relationship with human-derived isolates was observed. (C) 2019 Elsevier Ltd. All rights reserved.

Metadaten
Author details:	Daniela Numberger, Thomas Riedel, Gayle McEwen ORCiD, Ulrich Nübel, Martinique Frentrup, Isabel Schober, Boyke Bunk, Cathrin Spröer, Jörg Overmann, Hans-Peter Grossart ORCiD GND, Alex D. Greenwood
DOI:	https://doi.org/10.1016/j.anaerobe.2019.01.002
ISSN:	1075-9964
ISSN:	1095-8274
Pubmed ID:	https://pubmed.ncbi.nlm.nih.gov/30633971
Title of parent work (English):	Anaerobe
Publisher:	Elsevier
Place of publishing:	Oxford
Publication type:	Article
Language:	English
Date of first publication:	2019/01/08
Publication year:	2019
Release date:	2021/03/08
Tag:	Clostridioides difficile; Genomes; Sediment; Wastewater
Volume:	56
Number of pages:	5
First page:	22
Last Page:	26
Funding institution:	project grant (IRG 3 -Water) from the Leibniz Research Alliance - Leibniz Association, Germany [SAS-2015-FZB-LFV]; Federal State of Lower Saxony, Niedersachsisches Vorab [VWZN3215/ZN3266]
Organizational units:	Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie
DDC classification:	5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Peer review:	Referiert