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- dissociative electron attachment (8)
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- quasars: general (8)
- reanalysis (8)
- recombination (8)
- reproducibility (8)
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- risk perception (8)
- rotation (8)
- seed dispersal (8)
- selection (8)
- site effects (8)
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- stars: emission-line, Be (8)
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- time-series (8)
- tracking (8)
- transition (8)
- trends (8)
- ultrafast (8)
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- von Humboldts Hand (8)
- wh-questions (8)
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- Öffentliche Verwaltung (8)
- öffentliche Verwaltung (8)
- Anisotropy (7)
- Anpassung (7)
- Antike (7)
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- Design (7)
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- Digitale Plattformen (7)
- Dirac operator (7)
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- Emotionen (7)
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- Geschäftsprozessmanagement (7)
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- Interest (7)
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- Konversationsanalyse (7)
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- acquisition (7)
- age of acquisition (7)
- aggregation (7)
- air pollution (7)
- algorithms (7)
- alignment (7)
- allostatic load (7)
- amygdala (7)
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- bias (7)
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- coherence (7)
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- complexity (7)
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- developmental dyscalculia (7)
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- digitale Medien (7)
- discrepancy principle (7)
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- duplicate detection (7)
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- ecosystem functioning (7)
- effectiveness (7)
- energy policy (7)
- energy storage (7)
- ensemble Kalman filter (7)
- enzyme (7)
- enzyme catalysis (7)
- ethics (7)
- ethnicity (7)
- exercise therapy (7)
- extinction (7)
- extraction (7)
- extreme rainfall (7)
- fiction (7)
- films (7)
- first passage time (7)
- fiscal policy (7)
- flood (7)
- floodplain (7)
- flow (7)
- fluorescence correlation spectroscopy (7)
- food webs (7)
- function (7)
- functional magnetic resonance imaging (7)
- galaxies (7)
- galaxies: dwarf (7)
- galaxies: starburst (7)
- gene flow (7)
- global warming (7)
- graphene (7)
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- habitat (7)
- heart (7)
- heterogeneous catalysis (7)
- home range (7)
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- hydrolysis (7)
- ideology (7)
- imaging spectroscopy (7)
- immigration (7)
- income (7)
- infrared: stars (7)
- insula (7)
- interoceptive awareness (7)
- isotopes (7)
- jumping (7)
- kardiologische Rehabilitation (7)
- kinematics (7)
- land-use change (7)
- language contact (7)
- last glacial maximum (7)
- lipid metabolism (7)
- low-energy electrons (7)
- magnetism (7)
- meaning (7)
- mechanisms (7)
- media violence (7)
- memory retrieval (7)
- metaanalysis (7)
- metaphor (7)
- microbial ecology (7)
- microtubules (7)
- minerals (7)
- mobility (7)
- muscle (7)
- music (7)
- myocardial infarction (7)
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- neu gelesen (7)
- neuroplasticity (7)
- next generation sequencing (7)
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- nuclear envelope (7)
- nuclear lamina (7)
- nucleus (7)
- number (7)
- numerical simulations (7)
- openHPI (7)
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- organic photovoltaics (7)
- orthography (7)
- oscillations (7)
- pH (7)
- pain (7)
- palaeoecology (7)
- paleoecology (7)
- pandemic (7)
- parafoveal processing (7)
- parameter estimation (7)
- pathogens (7)
- perceptual span (7)
- phase transition (7)
- phase transitions (7)
- phonological awareness (7)
- photoelectron spectroscopy (7)
- planetary nebulae: general (7)
- planets and satellites: rings (7)
- plant diversity (7)
- plasmonics (7)
- plyometric training (7)
- polyelectrolytes (7)
- porous materials (7)
- predator-prey dynamics (7)
- presidential government (7)
- preview benefit (7)
- production (7)
- programming (7)
- pronoun resolution (7)
- propensity score matching (7)
- prosodic boundary cues (7)
- proteasome (7)
- protection (7)
- pulsars: general (7)
- quality (7)
- quantification (7)
- racism (7)
- reduction (7)
- repair (7)
- residual stress (7)
- retinol (7)
- rheology (7)
- roughness (7)
- scale development (7)
- screening (7)
- secular trend (7)
- sediment transport (7)
- seismic hazard (7)
- serotonin (7)
- shape-memory effect (7)
- sharing economy (7)
- silicon (7)
- size (7)
- soccer (7)
- social rejection (7)
- social support (7)
- socioeconomic status (7)
- software engineering (7)
- soil erosion (7)
- solar wind (7)
- sorption (7)
- spelling (7)
- stabile Isotope (7)
- standardization (7)
- stars: late-type (7)
- sunspots (7)
- surfactants (7)
- surveillance (7)
- tVNS (7)
- taste (7)
- techniques: image processing (7)
- terrorism (7)
- thermoresponsiv (7)
- thermoresponsive polymers (7)
- time series (7)
- tomato (7)
- tomography (7)
- treeline (7)
- trunk (7)
- trust (7)
- ultrasound (7)
- uplift (7)
- urbanization (7)
- vesicles (7)
- wh-in-situ (7)
- working memory capacity (7)
- world literature (7)
- youth sports (7)
- Ästhetik (7)
- 3D visualization (6)
- AFM (6)
- Adhäsion (6)
- Ageing (6)
- Agency (6)
- Alaska (6)
- Algeria (6)
- Alps (6)
- Anisotropy effect (6)
- Antibiotikaresistenz (6)
- Antikörper (6)
- Antwortmengenprogrammierung (6)
- Arsenolipids (6)
- Aufmerksamkeit (6)
- Australien (6)
- Autoritarismus (6)
- Bakterien (6)
- Bayesian data analysis (6)
- Berühren (6)
- Bewegung (6)
- Bewegungsökologie (6)
- Bioelectrocatalysis (6)
- Biogenic amine (6)
- Blockcopolymer (6)
- Briefe (6)
- C-reactive protein (6)
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- Centrosom (6)
- Chytridiomycota (6)
- Click chemistry (6)
- Clusteranalyse (6)
- Complexity (6)
- Computational modelling (6)
- Computerspiele (6)
- Copper (6)
- Data assimilation (6)
- Deep learning (6)
- Dielektrophorese (6)
- Diskriminierung (6)
- Diskurs (6)
- Dynamic NMR (6)
- Dynamik (6)
- EEG/ERP (6)
- Eastern Europe (6)
- Ellenberg indicator values (6)
- Emotions (6)
- Energy (6)
- Entzündung (6)
- Ethik (6)
- Fachdidaktik Latein (6)
- Fachwissen (6)
- Flood risk (6)
- Fluorescence spectroscopy (6)
- Forschendes Lernen (6)
- Föderalismus (6)
- Gammastrahlungsastronomie (6)
- Gene-environment interaction (6)
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- Geschmack (6)
- H II regions (6)
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- ISM: kinematics and dynamics (6)
- Indien (6)
- Informatik (6)
- Instructional quality (6)
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- Language acquisition (6)
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- Ludwig Leichhardt (6)
- Lysiphlebus fabarum (6)
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- Magnetotellurics (6)
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- Peptid (6)
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- Pflanzengeographie (6)
- Phenotypic plasticity (6)
- Phonons (6)
- Physikdidaktik (6)
- Poecilia mexicana (6)
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- Predictors (6)
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- Pyrenees (6)
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- RAFT polymerization (6)
- Raman (6)
- Recht (6)
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- Reinforcement learning (6)
- Reliability (6)
- Rezeption (6)
- Rheology (6)
- Ring current effect (6)
- Romania (6)
- Ruthenium (6)
- SDS-PAGE (6)
- Schadensmodellierung (6)
- School (6)
- Seesedimente (6)
- Selenium (6)
- Self-efficacy (6)
- Semantic Web (6)
- Sensorimotor training (6)
- Sentinel-1 (6)
- Sexual scripts (6)
- Sexual selection (6)
- Sexualität (6)
- Software (6)
- Soil erosion (6)
- Solanum tuberosum (6)
- Speech perception (6)
- Sphingosine 1-phosphate (6)
- Stable isotopes (6)
- Starkregen (6)
- Sternentwicklung (6)
- Steuerung (6)
- Storytelling (6)
- Stretch-shortening cycle (6)
- Subduction zone processes (6)
- Svalbard (6)
- TMS (6)
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- acid ceramidase (6)
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- amino acids (6)
- animal movement (6)
- antioxidants (6)
- apoptosis (6)
- architecture (6)
- assembly (6)
- behaviour (6)
- biodegradable polymers (6)
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- black holes (6)
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- bryophytes (6)
- capitalism (6)
- change detection (6)
- chloroplast (6)
- climate mitigation (6)
- cluster analysis (6)
- co-limitation (6)
- collective memory (6)
- community effect (6)
- competence (6)
- conversation analysis (6)
- copolymers (6)
- corpus study (6)
- costs (6)
- crisis management (6)
- crown compounds (6)
- crystal-structure (6)
- cultural diversity (6)
- cyber victimization (6)
- cyber-physical systems (6)
- cytoskeleton (6)
- databases (6)
- design (6)
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- diabetic nephropathy (6)
- dialogue (6)
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- diffuse radiation (6)
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- domestication (6)
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- dust, extinction (6)
- early warning (6)
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- exoplanets (6)
- expertise (6)
- extension (6)
- fNIRS (6)
- fabrication (6)
- facilitation (6)
- federalism (6)
- fertilization (6)
- first passage (6)
- flooding (6)
- fluorescent dyes (6)
- foreland basin (6)
- formal semantics (6)
- galaxies: abundances (6)
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- gamma-rays: general (6)
- gas (6)
- gelatin (6)
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- giving-up density (6)
- global (6)
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- heat (6)
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- heterocycles (6)
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- interfaces (6)
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- lithosphere (6)
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- mechanism (6)
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- mental simulation (6)
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- metabolites (6)
- methods: analytical (6)
- miRNA (6)
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- microarray (6)
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- microbial communities (6)
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- molecular rods (6)
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- nanoparticle (6)
- nanostructure (6)
- narration (6)
- negation (6)
- network analysis (6)
- neurodegeneration (6)
- neuromuscular control (6)
- neutron diffraction (6)
- nonergodicity (6)
- nucleation (6)
- numerical development (6)
- optimization (6)
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- oxygen (6)
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- palaeoclimate (6)
- parameters (6)
- parents (6)
- pattern formation (6)
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- perturbation (6)
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- respiration (6)
- retinol-binding protein 4 (6)
- return to work (6)
- risk assessment (6)
- risk factor (6)
- saccades (6)
- salinity gradient (6)
- scattering (6)
- scrambling (6)
- sedaDNA (6)
- sedimentary ancient DNA (6)
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- sodium (6)
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- speed (6)
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- stimuli-sensitive polymers (6)
- stroke (6)
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- structure elucidation (6)
- sulfite oxidase (6)
- support vector machine (6)
- synchrotron radiation (6)
- tailspike protein (6)
- teachers (6)
- tendinopathy (6)
- thaliana (6)
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- therapy (6)
- tools (6)
- topography (6)
- trade-offs (6)
- training adaptation (6)
- traits (6)
- transcription (6)
- transcriptional memory (6)
- type 2 diabetes mellitus (6)
- typology (6)
- ultrafast dynamics (6)
- uncertainty analysis (6)
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- variation (6)
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- walking (6)
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- definite pseudoclefts (5)
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- electropolymerization (5)
- elevated CO2 (5)
- ellipsis processing (5)
- emotion recognition (5)
- emulsion (5)
- energy efficiency (5)
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- energy metabolism (5)
- entity resolution (5)
- environment (5)
- environmental DNA (5)
- equality (5)
- equatorial electrojet (5)
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- event coincidence analysis (5)
- expectation (5)
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- eye-movement control (5)
- ferroelectret (5)
- field (5)
- filaments (5)
- film (5)
- financial markets (5)
- firm performance (5)
- first-passage time (5)
- fish (5)
- flood risk management (5)
- fluctuations (5)
- foraging (5)
- fragmentation (5)
- frailty (5)
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- fruit (5)
- functionalization (5)
- galaxies: haloes (5)
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- gene regulation (5)
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- komplexe Netzwerke (5)
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- maturation (5)
- maturity (5)
- mechanical properties (5)
- metabolic network (5)
- metacognition (5)
- metal (5)
- metal-organic frameworks (5)
- microbial diversity (5)
- microbial interactions (5)
- microbiology (5)
- microcontact printing (5)
- microgels (5)
- microparticles (5)
- microsaccades (5)
- microsimulation (5)
- mind wandering (5)
- mineralization (5)
- minimum wage (5)
- mitochondrial genome (5)
- molekulare Motoren (5)
- monoclonal antibodies (5)
- morphologically complex words (5)
- mouse (5)
- multiblock copolymer (5)
- multicore architectures (5)
- multiplicative noise (5)
- musicality (5)
- narrative (5)
- natural hazard (5)
- neovascularization (5)
- neuromuscular (5)
- new public management (5)
- next-generation sequencing (5)
- non-fullerene acceptors (5)
- nonlinear (5)
- nonlinear time series analysis (5)
- norepinephrine (5)
- oncology (5)
- online (5)
- online hate (5)
- ontology (5)
- opposition (5)
- outcome (5)
- oxidation (5)
- paleomagnetism (5)
- palladium (5)
- parental mediation (5)
- partial melting (5)
- participatory research (5)
- particle-in-cell simulations (5)
- pathways (5)
- perceptual reorganization (5)
- periodization (5)
- permafrost degradation (5)
- permeability (5)
- perovskite (5)
- peroxides (5)
- phase separation (5)
- phenomenology (5)
- philosophy (5)
- phonology (5)
- photophysics (5)
- photovoltaics (5)
- physical performance (5)
- physics education (5)
- planet-star interactions (5)
- plant community (5)
- plant functional trait (5)
- plant functional traits (5)
- plateau (5)
- plyometric exercise (5)
- politeness (5)
- political education (5)
- poly(lactic acid) (5)
- polyethylene (5)
- polymer chemistry (5)
- polymer degradation (5)
- polymorphism (5)
- polypeptide (5)
- population genomics (5)
- populations (5)
- pornography (5)
- positive selection (5)
- postural sway (5)
- poverty (5)
- predictability (5)
- preferences (5)
- preferential flow (5)
- pressure (5)
- presupposition (5)
- private households (5)
- probabilistic (5)
- probiotics (5)
- problem solving (5)
- process mining (5)
- professionalization (5)
- prosocial behavior (5)
- protein modification (5)
- protein-protein interactions (5)
- psychometric properties (5)
- psychotherapy process (5)
- pupillometry (5)
- purification (5)
- qualitative analysis (5)
- quantitative Analyse (5)
- quantitative analysis (5)
- quantum field theory (5)
- race (5)
- random diffusivity (5)
- random-walks (5)
- range shifts (5)
- rare earth elements (5)
- reading comprehension (5)
- real-time rendering (5)
- reconstruction (5)
- record (5)
- reflexives (5)
- regional development (5)
- rejection sensitivity (5)
- relational aggression (5)
- relativistic jets (5)
- repetition (5)
- reproductive success (5)
- research projects (5)
- resonance energy transfer (5)
- resource competition (5)
- rhythmic grouping (5)
- rice (5)
- risk analysis (5)
- risk communication (5)
- risk management (5)
- risk-factors (5)
- rotifers (5)
- running (5)
- rural (5)
- salicylic acid (5)
- salt stress (5)
- savanna (5)
- scaling (5)
- scenario (5)
- scenarios (5)
- school shooting (5)
- seed bank (5)
- seismic noise (5)
- seismic tomography (5)
- seismicity (5)
- selectivity (5)
- self-employment (5)
- self-evaluation (5)
- semi-arid (5)
- semi-parliamentary government (5)
- sensitivity analysis (5)
- sentence production (5)
- sentiment analysis (5)
- service-oriented systems engineering (5)
- shape-memory polymers (5)
- shotgun sequencing (5)
- silica (5)
- single-case experimental design (5)
- single-particle tracking (5)
- smart contracts (5)
- social (5)
- social acceptance (5)
- social networking sites (5)
- software development (5)
- sol-gel (5)
- spatial autocorrelation (5)
- spatial cognition (5)
- spatial-distribution (5)
- speciation (5)
- species coexistence (5)
- species distribution models (5)
- spectra (5)
- speech motor control (5)
- sphingosine-1-phosphate (5)
- sport-specific performance (5)
- sports (5)
- standards (5)
- starch phosphorylation (5)
- stars: chemically peculiar (5)
- stars: mass loss (5)
- state (5)
- statistical physics (5)
- stellar activity (5)
- stellar evolution (5)
- stochastic differential equations (5)
- stochastic models (5)
- strategic growth adjustments (5)
- strategy (5)
- streamflow (5)
- striking combat sports (5)
- students (5)
- stunting (5)
- sucrose (5)
- sulfate reduction (5)
- supergiants (5)
- superstatistics (5)
- surface processes (5)
- surface relief grating (5)
- surfaces (5)
- survey (5)
- tRNA (5)
- tax reform (5)
- teacher (5)
- tectonic geomorphology (5)
- theory of mind (5)
- thermal modeling (5)
- thermodynamic stability (5)
- thermodynamics (5)
- tiefes Lernen (5)
- top-down control (5)
- tourism (5)
- trajectories (5)
- transcriptome (5)
- trend analysis (5)
- tundra (5)
- tunneling (5)
- tyramine (5)
- ultraviolet: ISM (5)
- uncertainties (5)
- uncertainty quantification (5)
- upconversion (5)
- urban (5)
- validation study (5)
- vegetation change (5)
- victim blame (5)
- virus (5)
- visual culture (5)
- vocational training (5)
- voltage losses (5)
- water resources (5)
- weather extremes (5)
- weight (5)
- welfare (5)
- wetland (5)
- wetlands (5)
- words (5)
- workplace (5)
- xanthine dehydrogenase (5)
- öffentlicher Sektor (5)
- ökologische Modellierung (5)
- 1814-1831 (4)
- 2nd-language (4)
- 3D-Visualisierung (4)
- 4 (4)
- ABC transporter (4)
- ARPES (4)
- ASIC (4)
- ATRP (4)
- Academic achievement (4)
- Academic self-concept (4)
- Achilles tendon (4)
- Actin cytoskeleton (4)
- Active tectonics (4)
- Adipose tissue (4)
- Adolescent (4)
- Aerosol (4)
- Aerosols (4)
- Affordances (4)
- Agrammatism (4)
- Aimé Bonpland (4)
- Akzeptanz (4)
- Alexithymia (4)
- Alignment (4)
- Allometry (4)
- Alter (4)
- Alzheimer (4)
- Amino acids (4)
- Andreas Gryphius (4)
- Anisotropie (4)
- Ankle sprain (4)
- Anthropogene Klimaänderung (4)
- Antiplasmodial (4)
- Arabidopsis-thaliana (4)
- Arbeit (4)
- Arbeitsmarktpolitik (4)
- Aridity (4)
- Arsenic (4)
- Arsenic-containing fatty acids (4)
- Astroteilchenphysik (4)
- Atlantic meridional overturning circulation (4)
- Atlantic studies (4)
- Atmosphere (4)
- Attrition (4)
- Augenbewegungen (4)
- Augmented reality (4)
- Ausbreitung (4)
- Auxin (4)
- Averroes (4)
- Azobenzene (4)
- Bakteriophagen (4)
- Bayesian analysis (4)
- Bayesian networks (4)
- Beratung (4)
- Bewertung (4)
- Biaryls (4)
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- Biofilms (4)
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- Bodenhydrologie (4)
- Body dissatisfaction (4)
- Body size (4)
- Botanik (4)
- Brachypodium hybridum (4)
- Bragg peak (4)
- Business Process Management (4)
- CCM (4)
- CPS (4)
- Ca2+ (4)
- Calciumphosphat (4)
- Carotenoids (4)
- Catalysis (4)
- Cellulose (4)
- Cenozoic (4)
- Chemotaxis (4)
- Childhood adversity (4)
- Chinese loess (4)
- Chiroptera (4)
- Cholesterol (4)
- Chronic back pain (4)
- Chronic conditions (4)
- Climate variability (4)
- Closure Positive Shift (CPS) (4)
- Clustering (4)
- Coexistence (4)
- Collatz (4)
- Communion (4)
- Computational seismology (4)
- Computerlinguistik (4)
- Controlled source seismology (4)
- Correlation (4)
- Coupled oscillators (4)
- Cross-coupling (4)
- Cryo-SEM (4)
- Crystal lattices (4)
- Crystal structure (4)
- Cytochrome P450 (4)
- Cytochrome c (4)
- DNA Origami (4)
- DNA damage response (4)
- DNA metabarcoding (4)
- DNA preservation (4)
- DNA strand breaks (4)
- Daniel Kehlmann (4)
- Data Profiling (4)
- Dead Sea Transform (4)
- Debugging (4)
- Dementia (4)
- Democracy (4)
- Demokratisierung (4)
- Density functional calculations (4)
- Denudation (4)
- Depressive symptoms (4)
- Determinants (4)
- Diagnostik (4)
- Digitale Medien (4)
- Digitale Transformation (4)
- Digitalization (4)
- Dissertation (4)
- Dopamine (4)
- Dormancy (4)
- Drehbuch (4)
- Dual-process (4)
- Duration (4)
- Dynamic pricing (4)
- Dynamical systems (4)
- Dynamics (4)
- Dysphagie (4)
- E-Mail Tracking (4)
- ENSO (4)
- EPR spectroscopy (4)
- Earthquake dynamics (4)
- Earthquake interaction (4)
- Earthquakes (4)
- East African Rift (4)
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- Eastern Cordillera (4)
- Eclogite (4)
- Economics (4)
- Ecuador (4)
- Einkommen (4)
- Eisen (4)
- Electrets (4)
- Electrochemistry (4)
- Electron transfer (4)
- Elektrokatalyse (4)
- Elektrolumineszenz (4)
- EnMAP (4)
- Enceladus (4)
- Endothelin (4)
- Energiespeicher (4)
- Englisch (4)
- Enterprise-Resource-Planning (4)
- Enzyme (4)
- Eocene (4)
- Epigenetik (4)
- Erdmantel (4)
- Erdrutsch (4)
- Europäische Integration (4)
- Europäisierung (4)
- Event synchronization (4)
- Event-related potential (4)
- Examen critique (4)
- Exercise therapy (4)
- Expertenbefragung (4)
- Extreme rainfall (4)
- Eye-Tracking (4)
- Eye-movement monitoring (4)
- FLASH (4)
- FTIR spectroscopy (4)
- Fatigue (4)
- Ferroelectrets (4)
- Ferroelektrete (4)
- Fertilization (4)
- Fettsäuren (4)
- Flooding (4)
- Floods (4)
- Flow-Erleben (4)
- Flower buds (4)
- Fluid-rock interaction (4)
- Forecasting (4)
- Foreign Policy (4)
- Forest management (4)
- Forstwirtschaft (4)
- Fourier analysis (4)
- Fragmentierung (4)
- Französisch (4)
- Frauenliteratur (4)
- Fredholm complexes (4)
- Friedrich Wilhelm III. (4)
- Functional diversity (4)
- Fuzzy logic (4)
- GC-MS (4)
- GDF15 (4)
- GRACE (4)
- Galaxy: structure (4)
- Gamification (4)
- Gas (4)
- Gaussian processes (4)
- Gelatin (4)
- Genexpression (4)
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- Geochronologie (4)
- Geographieunterricht (4)
- Geothermie (4)
- Geowissenschaften (4)
- Geschichte der Poetik (4)
- Geschichtsschreibung (4)
- Geschäftsmodell (4)
- Gestational diabetes (4)
- Givenness (4)
- Glaciation (4)
- Gleichstellung (4)
- Glucosinolates (4)
- Gondwana (4)
- Graphtransformationen (4)
- Ground-penetrating radar (4)
- Growth (4)
- Grundwasser (4)
- H.E.S.S. (4)
- HRTEM (4)
- Hermeneutik (4)
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- Himalaja (4)
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- Hochdruck (4)
- Hochschulen (4)
- Hochschullehre (4)
- Hodge theory (4)
- Home range (4)
- Human (4)
- Human Rights (4)
- Human evolution (4)
- Human impact (4)
- Hydrogele (4)
- Hypoxia (4)
- ICA (4)
- ICSS (4)
- ISM: molecules (4)
- IT-Infrastruktur (4)
- Identity (4)
- Ideologie (4)
- Immobilization (4)
- Implementation (4)
- In-Memory technology (4)
- Income (4)
- India-Asia collision (4)
- Indian Monsoon (4)
- Indian monsoon (4)
- Influenza (4)
- Inhaltsanalyse (4)
- Injury (4)
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- Internationale Beziehungen (4)
- Internationale Politik (4)
- Interspecific interactions (4)
- Intuitive eating (4)
- IoT (4)
- Ionenmobilitätsspektrometrie (4)
- Ionic liquid (4)
- Irradiation (4)
- Isoflavone (4)
- JUB1 (4)
- Java (4)
- Johann Gottfried Herder (4)
- Kalahari (4)
- Kampfsport (4)
- Kardinal Franz Ehrle (4)
- Katalyse (4)
- Kenia (4)
- Kenya Rift (4)
- Kettle holes (4)
- KiK-net (4)
- Kind (4)
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- Knees (4)
- Koexistenz (4)
- Kohlenhydrate (4)
- Kolloid (4)
- Kompetenz (4)
- Kompetenzen (4)
- Kompetenzentwicklung (4)
- Korrespondenz (4)
- Kosmopolit (4)
- Kreisgebietsreform (4)
- Kyrgyzstan (4)
- LGM (4)
- Lake (4)
- Landkreise (4)
- Landnutzungsänderung (4)
- Landschaftsentwicklung (4)
- Langevin equation (4)
- Lefschetz number (4)
- Legs (4)
- Lehramtsstudium (4)
- Lehrevaluation (4)
- Lehrkräfte (4)
- Lernmotivation (4)
- Lernstrategien (4)
- Lernumgebung (4)
- Levy walk (4)
- Lexical tone (4)
- Limnology (4)
- Linear mixed model (4)
- Lively Kernel (4)
- Livestock (4)
- Luftverschmutzung (4)
- Lumineszenz (4)
- Lyrik (4)
- MALDI-TOF-MS (4)
- MATLAB (4)
- MCMC (4)
- MRI (4)
- Magnetic properties (4)
- Magnetism (4)
- Malnutrition (4)
- Martial arts (4)
- Mathematical model (4)
- Mathematikdidaktik (4)
- Maule earthquake (4)
- Media (4)
- Mediterranean (4)
- Mediterranean Sea (4)
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- Metabolisches Syndrom (4)
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- Metaphysik (4)
- Methylmercury (4)
- Microcystis (4)
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- Middle childhood (4)
- Mikrotubuli (4)
- Militärgeschichte (4)
- Mind wandering (4)
- Mineralisation (4)
- Mixed methods (4)
- Modalität (4)
- Model-Driven Engineering (4)
- Molecular modeling (4)
- Molybdenum (4)
- Mongolei (4)
- Monoclonal antibody (4)
- Monte Carlo method (4)
- Monte-Carlo simulations (4)
- Morphological processing (4)
- Motor control (4)
- Multifunctionality (4)
- Museum (4)
- Mycotoxins (4)
- Mythos (4)
- NEXAFS (4)
- NGS (4)
- NZO (4)
- Nachhaltige Entwicklung (4)
- Naher Osten (4)
- Nanoparticle (4)
- Nanostructure (4)
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- Nationalsozialismus (4)
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- Neotethys (4)
- Neu-Spanien (4)
- Neue Ökonomische Geographie (4)
- Neujahrsempfang (4)
- Neuroscience (4)
- New Zealand (4)
- New-Zealand (4)
- Nitrate (4)
- Nonlinear Dynamics (4)
- Nordeste (4)
- Northern Asia (4)
- Nrf2 (4)
- Number processing (4)
- NutriAct Family Study (4)
- Nährstoffe (4)
- Older patients (4)
- Oman (4)
- Online-Lernen (4)
- Open Source (4)
- Operational momentum (4)
- Organic matter (4)
- Organisation (4)
- Organisationen (4)
- Othering (4)
- Output-Analyse (4)
- Overland flow (4)
- Ozon (4)
- PCR (4)
- PLFA (4)
- Pacific Ocean (4)
- Pacific studies (4)
- Palaeoclimatology (4)
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- Palestine (4)
- Paläoökologie (4)
- Palästina (4)
- Parafoveal (4)
- Parafoveal processing (4)
- Parsing (4)
- Participation (4)
- Pavlovian-to-instrumental transfer (4)
- Perovskites (4)
- Persistence (4)
- Personalization (4)
- Pflanzen (4)
- Phase (4)
- Phasenübergang (4)
- Philosophische Anthropologie (4)
- Philosophy (4)
- Phonologie (4)
- Photoelektronenspektroskopie (4)
- Photon Density Wave spectroscopy (4)
- Phylogenetics (4)
- Pinus sylvestris (4)
- Placenta (4)
- Planetary rings (4)
- Plasmodium falciparum (4)
- Political Science (4)
- Politikunterricht (4)
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- Polizei (4)
- Polymerisation (4)
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- Predictive models (4)
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- Proteine (4)
- Prototyping (4)
- Psychometric properties (4)
- Psychotherapy research (4)
- Quality management (4)
- Qualitätsmanagement (4)
- Quantenpunkte (4)
- Quantitative Trait Locus (4)
- Quantitative Trait Locus analysis (4)
- RAFT-Polymerisation (4)
- RNAseq (4)
- Radiation belts (4)
- Random Forests (4)
- Rassendiskriminierung (4)
- Rauschen (4)
- Reachability (4)
- Reading development (4)
- Reading strategies (4)
- Rechtspopulismus (4)
- Rechtswissenschaft (4)
- Recovery (4)
- Recurrence plot (4)
- Refugees (4)
- Regeneration (4)
- Regionalentwicklung (4)
- Regularisierung (4)
- Reisetagebücher (4)
- Relativsätze (4)
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- Rezeptor (4)
- Rhizosphere (4)
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- Romanische Sprachen (4)
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- Rückenschmerzen (4)
- SDS PAGE (4)
- Saccharomyces cerevisiae (4)
- Salivary gland (4)
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- Sampling (4)
- Scale development (4)
- Schweden (4)
- Schwefel (4)
- Schülermaterial (4)
- Scrum (4)
- Second World War (4)
- Sediment connectivity (4)
- Seismic attenuation (4)
- Seismic noise (4)
- Self-control (4)
- Self-employment (4)
- Self-esteem (4)
- Self-paced reading (4)
- Self-regulated learning (4)
- Self-regulation (4)
- Semiarid (4)
- Senescence (4)
- Sex (4)
- Sexual victimization (4)
- Sick leave (4)
- Simulated patients (4)
- Simulationen (4)
- Slavistik (4)
- Slumming (4)
- Slumtourismus (4)
- Soil hydrology (4)
- Sol-Gel (4)
- Solarzellen (4)
- Solidago gigantea (4)
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- Soviet Union (4)
- Species distribution modelling (4)
- Species richness (4)
- Speichel (4)
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- Standardized patients (4)
- Staphylococcus aureus (4)
- Start-Up Subsidies (4)
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- System (4)
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- TPACK (4)
- TSNMRS (4)
- Tagebuch (4)
- Tailspike (4)
- Teacher motivation (4)
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- Tenside (4)
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- Thermoresponsive (4)
- ToF-SIMS (4)
- Toeplitz operators (4)
- Tourismus (4)
- Trace elements (4)
- Transdisziplinarität (4)
- Transfer function (4)
- Transkriptom (4)
- Transkriptomik (4)
- Triassic (4)
- Tropical forest (4)
- Tso Moriri Lake (4)
- Turkish-German bilingualism (4)
- Typ-2-Diabetes (4)
- Typologie (4)
- Tyramin (4)
- UAV (4)
- UV (4)
- Umweltpolitik (4)
- Uncertainties (4)
- Underspecification (4)
- Understanding (4)
- University of Potsdam (4)
- Unternehmen (4)
- V-ATPase (4)
- VIIRS DNB (4)
- Van Allen Probes (4)
- Verfassungsrecht (4)
- Verhandlungen (4)
- Verification (4)
- Vernetzung (4)
- Vertrauen (4)
- Verwaltungswissenschaft (4)
- Videoanalyse (4)
- Virtualisierung (4)
- WA-PLS (4)
- Wasserhaushalt (4)
- Weight (4)
- Weight bias internalization (4)
- Weiterbildung (4)
- Wellenleiter (4)
- West Africa (4)
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- West Bohemia (4)
- Wetter (4)
- Wissenschaft (4)
- Wissenstransfer (4)
- Wohlbefinden (4)
- Work ability (4)
- X-ray emission spectroscopy (4)
- X-ray scattering (4)
- X-rays (4)
- Xanthomonas (4)
- absorption (4)
- accretion (4)
- accretion, accretion disks (4)
- accuracy (4)
- achilles tendinopathy (4)
- actin (4)
- action language (4)
- action processing (4)
- action words (4)
- actuation (4)
- adaptive force (4)
- additive particles (4)
- adherence (4)
- adipogenesis (4)
- adjectives (4)
- advanced dynamic flow (4)
- aerosol (4)
- affective (4)
- agency (4)
- agent-based model (4)
- agility (4)
- agreement attraction (4)
- aldehyde oxidase (4)
- allelopathy (4)
- alternatives (4)
- amerikanische Reisetagebücher (4)
- anaphors (4)
- anisotropy (4)
- anorexia nervosa (4)
- antifouling (4)
- antilocality (4)
- aphids (4)
- app (4)
- aquatic ecosystems (4)
- aqueous-solution (4)
- arabidopsis (4)
- arabidopsis-thaliana (4)
- argumentation (4)
- arsenolipids present (4)
- association (4)
- astronomy (4)
- astrophysical plasmas (4)
- attachment (4)
- authenticity (4)
- authority (4)
- automatic evaluation (4)
- automatic evaluations (4)
- automation (4)
- beliefs (4)
- bibliometrics (4)
- biodiversity exploratories (4)
- bioelectrocatalysis (4)
- biogenic amine (4)
- biogeochemistry (4)
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- biomarkers (4)
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- categories (4)
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- coating (4)
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- coefficient (4)
- coercion (4)
- coevolution (4)
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- collagen (4)
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- common vole (4)
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- competencies (4)
- compliance (4)
- computer-based training (4)
- conceptualization (4)
- concrete (4)
- conduct problems (4)
- conductivity (4)
- confocal microscopy (4)
- content areas (4)
- content knowledge (4)
- content-addressable memory (4)
- context (4)
- conversational agents (4)
- conversion (4)
- convolutional neural network (4)
- copper(II) (4)
- core (4)
- corpus linguistics (4)
- cosmic-ray neutron sensing (4)
- cosmology (4)
- covariance (4)
- creep (4)
- critical theory (4)
- crop (4)
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- cross-cultural comparison (4)
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- crosslinking (4)
- crust (4)
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- definition (4)
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- diachrony (4)
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- dictator game (4)
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- digital (4)
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- effect (4)
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- emissions (4)
- emotional expression (4)
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- empowerment (4)
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- enhancement (4)
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- evaluative study (4)
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- expectations (4)
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- fault (4)
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- finger counting (4)
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- fiscal federalism (4)
- floral scent (4)
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- fluid inclusions (4)
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- formal verification (4)
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- framework (4)
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- garden-path effect (4)
- gaze-contingent displays (4)
- gene regulatory networks (4)
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- geography (4)
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- hormones (4)
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- infrastructure (4)
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- intrusion detection (4)
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- ionic strength (4)
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- justice (4)
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- knickpoint (4)
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- komplexe Systeme (4)
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- lactate (4)
- land-use intensity (4)
- language change (4)
- large-scale structure of Universe (4)
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- left periphery (4)
- lexical access (4)
- lexicon (4)
- lichens (4)
- life satisfaction (4)
- lifetime income (4)
- light variability (4)
- line: identification (4)
- linear hypersubstitution (4)
- linear mixed models (4)
- lipidomics (4)
- literacy acquisition (4)
- loading rate (4)
- local time (4)
- locomotion (4)
- locus coeruleus (4)
- locus of control (4)
- low-back-pain (4)
- lower critical solution temperature (4)
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- mammals (4)
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- meadow (4)
- measurement invariance (4)
- mechanical tendinous oscillations (4)
- media use (4)
- memory effects (4)
- mesenchymal stem cells (4)
- mesoporous materials (4)
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- metabolite (4)
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- methanogenic archaea (4)
- methyl orange (4)
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- mid-temperature transition (4)
- mild cognitive impairment (4)
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- mixtures (4)
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- mood (4)
- morality (4)
- morphogenesis (4)
- motivational interviewing (4)
- mowing (4)
- multilevel analysis (4)
- multivariate statistics (4)
- muscle oxygen saturation (4)
- museum specimens (4)
- music information retrieval (4)
- n-alkanes (4)
- nachhaltige Chemie (4)
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- non-photorealistic rendering (4)
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- noun (4)
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- ocean acidification (4)
- ocean color remote sensing (4)
- online course creation (4)
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- optimal foraging (4)
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- optimism (4)
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- osmotic-pressure (4)
- osteoblast (4)
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- part 1 (4)
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- receptor (4)
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- relatedness (4)
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- equation (3)
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- grade-skipping (3)
- gradient boosting (3)
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- grain-size distribution (3)
- grammatical illusion (3)
- granite (3)
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- graph constraints (3)
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- implementation (3)
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- intrinsically disordered proteins (3)
- intuition (3)
- invasion (3)
- inverse analysis (3)
- inverse micelles (3)
- inverse problem (3)
- inverse theory (3)
- ion exchange (3)
- ion transport (3)
- ionogel (3)
- ionogels (3)
- ionothermal synthesis (3)
- islands (3)
- isokinetic (3)
- isotopic composition (3)
- isotopic tiling theory (3)
- iterative regularization (3)
- job creation (3)
- job demands-resources model (3)
- job satisfaction (3)
- job search (3)
- junge Erwachsene (3)
- just transition (3)
- kana (3)
- kanji (3)
- keratinocytes (3)
- kernel density estimation (3)
- kettle hole (3)
- kinetic instabilities (3)
- kognitive Modellierung (3)
- kollektives Gedächtnis (3)
- kommunale Demokratie (3)
- kommunale Entscheidungsprozesse (3)
- komplexes Netzwerk (3)
- körperliche Fitness (3)
- l-cysteine desulfurase (3)
- labeling (3)
- lactate threshold (3)
- land cover change (3)
- land-use (3)
- landscape diversity (3)
- landscape homogenization (3)
- langevin equation (3)
- language attitudes (3)
- language courses (3)
- languages (3)
- large-scale (3)
- large-scale assessment (3)
- last glacial period (3)
- late Holocene (3)
- latitude (3)
- latitudinal gradient (3)
- leaf (3)
- leaf development (3)
- leaf senescence (3)
- leaking (3)
- learning and memory (3)
- learning factories (3)
- learning factory (3)
- learning styles (3)
- lebenslanges Lernen (3)
- lesson evaluation (3)
- lesson planning (3)
- lexical development (3)
- lexical tone (3)
- lexical tones (3)
- liberalism (3)
- life course (3)
- life-history traits (3)
- light intensity (irradiance) (3)
- limits (3)
- line: profiles (3)
- linear programming (3)
- linearized gravity (3)
- linke Peripherie (3)
- lipid (3)
- liquid-phase catalysis (3)
- literatures of the world (3)
- liver metabolism (3)
- load (3)
- local (3)
- logarithmic source condition (3)
- lokale Anpassung (3)
- long-distance dispersal (3)
- losses (3)
- lower (3)
- lower thermosphere (3)
- lupin (3)
- lysosomal storage disorders (3)
- lysosome (3)
- ländliche Entwicklung (3)
- mAb disposition (3)
- magnetic reconnection (3)
- magnetic resonance imaging (3)
- magnetoconvection (3)
- magnetotactic bacteria (3)
- magnetotaktische Bakterien (3)
- magnitude estimation (3)
- maintenance of functional diversity (3)
- major depression (3)
- majority rule (3)
- manufacturing (3)
- marine terrace (3)
- marine terraces (3)
- masculinity (3)
- mass index (3)
- mass media (3)
- mass wasting (3)
- massereiche Sterne (3)
- matching (3)
- mathematical modelling (3)
- mathematical precursor (3)
- mechanotransduction (3)
- media education (3)
- medicine (3)
- melatonin (3)
- memory and delay (3)
- mental imagery (3)
- mesocrystals (3)
- mesoporous (3)
- mesoporös (3)
- metabolic disease (3)
- metagenomics (3)
- metal nanoparticles (3)
- metal nitrides (3)
- meteorology (3)
- methane hydrate (3)
- method (3)
- methodological quality (3)
- methods: statistical (3)
- miRNAs (3)
- micro degree (3)
- micro-credential (3)
- microemulsion (3)
- microgel (3)
- micropolitics (3)
- microstructures (3)
- microwave irradiation (3)
- migrants (3)
- military culture (3)
- military history (3)
- miniemulsion (3)
- minimal pairs (3)
- minimax convergence rates (3)
- mining lakes (3)
- minorities (3)
- missing-VP effect (3)
- mitochondrial dysfunction (3)
- mitogenome (3)
- mitogenomes (3)
- mittlere Kindheit (3)
- mobile application (3)
- modal verbs (3)
- modality compatibility (3)
- model coupling (3)
- model transformation (3)
- model uncertainty (3)
- model-driven engineering (3)
- modellgetriebene Entwicklung (3)
- moderne jüdische Geschichte (3)
- modularity (3)
- molecular doping (3)
- molecular dynamics simulations (3)
- molybdenum (3)
- molybdoenzyme (3)
- monetary incentive delay task (3)
- monoklonale Antikörper (3)
- monomer (3)
- monomers (3)
- morpho-orthography (3)
- morphological decomposition (3)
- morphological priming (3)
- morphological structure (3)
- morphometrics (3)
- morphosyntax (3)
- motion capture (3)
- motor resonance (3)
- motor skills (3)
- motor system (3)
- movement kinematics (3)
- mu-DSC (3)
- multi-agent system (3)
- multi-level system (3)
- multicultural policy (3)
- multiculturalism (3)
- multifunctional polymers (3)
- multilevel modelling (3)
- multiobjective calibration (3)
- multiple stressors (3)
- multiscale analysis (3)
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- multivariate Statistik (3)
- muscle action (3)
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- musculoskeletal and neural physiological phenomena (3)
- music cognition (3)
- music perception (3)
- music therapy (3)
- mutation (3)
- mycotoxins (3)
- myth (3)
- nanoclusters (3)
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- nanomaterials (3)
- nanoparticle dimers (3)
- nanoscale heat transfer (3)
- naphthalenes (3)
- naphthalimide (3)
- natal dispersal (3)
- nationalism (3)
- natural habitats (3)
- nearshore zone (3)
- need satisfaction (3)
- needs (3)
- negative numbers (3)
- neoliberalism (3)
- net ecosystem exchange (3)
- neural (3)
- neurofeedback (3)
- neuromuscular adaptation (3)
- neuromuscular functionality (3)
- neutral endopeptidase (3)
- neutron (3)
- neutron reflectometry (3)
- niche and fitness differences (3)
- niche width (3)
- nichtlineare Optik (3)
- nitrogen limitation (3)
- noisy systems (3)
- non-Langevin recombination (3)
- non-athletes (3)
- non-categoricity (3)
- nonfullerene acceptors (3)
- nonlinear optics (3)
- nonradiative voltage losses (3)
- nonstationarity (3)
- northern high latitudes (3)
- novel ecosystems (3)
- novelty (3)
- nucleobases (3)
- number concepts (3)
- number processing (3)
- numerical modelling (3)
- numerical models (3)
- numerische Kognition (3)
- nutrient limitation (3)
- nutrient retention (3)
- nutrient supply (3)
- nutritional ecology (3)
- oarsmen (3)
- object search (3)
- occupational prognosis (3)
- ocean heat uptake (3)
- octopamine (3)
- offspring (3)
- oil palm (3)
- older patients (3)
- olivine (3)
- omega-3 fatty acids (3)
- on-water performance (3)
- one-carbon metabolism (3)
- online course (3)
- online discrimination (3)
- online disinhibition (3)
- online learning (3)
- online teaching (3)
- open (3)
- open education (3)
- open innovation (3)
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- operating systems (3)
- optical manipulation (3)
- optical spectroscopy (3)
- optische Fasern (3)
- order (3)
- organ size (3)
- organic electronics (3)
- organic solar cell (3)
- organic synthesis (3)
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- organische Solarzellen (3)
- organisches Material (3)
- organizations (3)
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- origin (3)
- origins (3)
- orogenic peridotite (3)
- orogeny (3)
- osteoclast (3)
- outcome measures (3)
- outlier detection (3)
- output analysis (3)
- overweight children (3)
- oxygen isotopes (3)
- oxygen reduction reaction (3)
- ozone (3)
- palaeolimnology (3)
- paleo-sediment (3)
- paleogenetics (3)
- paleovegetation (3)
- paper (3)
- parafoveal (3)
- parafoveal-on-foveal effect (3)
- parallel processing (3)
- parameterization (3)
- parasitoid (3)
- parchment (3)
- parenthetic verbs (3)
- parliamentary opposition (3)
- particles (3)
- party competition (3)
- pasture (3)
- patchy particles (3)
- patient education (3)
- pea (3)
- peak height velocity (3)
- peak torque (3)
- peatlands (3)
- pedagogical content knowledge (3)
- peer influences (3)
- peers (3)
- perceived stress (3)
- perception and action (3)
- performance information use (3)
- periphyton (3)
- permafrost ecosystems (3)
- personality traits (3)
- perspective taking (3)
- phagocytosis (3)
- phase (3)
- phase behavior (3)
- philosophy of science (3)
- phonological development (3)
- phonotactics (3)
- phospholipids (3)
- photocatalytic water splitting (3)
- photocurrent generation (3)
- photoionization (3)
- photon density wave spectroscopy (3)
- photosensitive surfactants (3)
- photoswitches (3)
- photosynthetic rate (3)
- photovoltaic materials (3)
- physical aggression (3)
- physical conditioning human (3)
- phytoplankton communities (3)
- piezoelectret (3)
- piezoelectrets (3)
- pigment composition (3)
- pilot study (3)
- pitch angle (3)
- planets and satellites: individual (Saturn) (3)
- plant cell wall (3)
- plant invasion (3)
- plant science (3)
- plant volatiles (3)
- plant-plant interactions (3)
- plasma-membrane (3)
- plausibility (3)
- pluvial floods (3)
- plyometrics (3)
- poetry (3)
- point clouds (3)
- policy evaluation (3)
- political elites (3)
- political philosophy (3)
- political sociology (3)
- politische Bildung (3)
- politische Eliten (3)
- pollination (3)
- poly(A) polymerase (3)
- poly(N-isopropylacrylamide) (3)
- poly(ether imide) (3)
- polyadenylation (3)
- polyesters (3)
- polyglycerol (3)
- polymer solar cells (3)
- polymersomes (3)
- population growth rate (3)
- populism (3)
- positioning (3)
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- post-natal (3)
- potassium channel (3)
- potato (3)
- power spectral analysis (3)
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- pp-wave solutions (3)
- practice (3)
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- pre-service teachers (3)
- precaution (3)
- precision agriculture (3)
- predation risk (3)
- predator-prey (3)
- predator-prey model (3)
- prediction models (3)
- preference (3)
- prefixes (3)
- preschool (3)
- pressures (3)
- prevalence information (3)
- primary metabolism (3)
- primary school children (3)
- printing (3)
- prior knowledge (3)
- proactive personality (3)
- probability (3)
- probability density function (3)
- probes (3)
- problem-solving (3)
- problems (3)
- process analytical technology (3)
- process modeling (3)
- process modelling (3)
- production planning (3)
- proliferation (3)
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- prosodic cues (3)
- prosody processing (3)
- prospective (3)
- prostaglandin E2 (3)
- prostate cancer (3)
- proteasomal degradation (3)
- protective factors (3)
- protein binding (3)
- protein restriction (3)
- protein search (3)
- protein self-assembly (3)
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- protein-phenol interactions (3)
- proteomic analysis (3)
- protonation (3)
- prototype-willingness-model (3)
- prozessorientierte Didaktik (3)
- psycho-oncology (3)
- psychopathology (3)
- psychophysiology (3)
- psychopower (3)
- puberty (3)
- public (3)
- public good (3)
- public service delivery (3)
- public transport (3)
- publication bias (3)
- pulling isometric muscle action (PIMA) (3)
- pump-probe (3)
- punishment (3)
- quantitative research (3)
- quantum dynamics (3)
- quantum friction (3)
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- quasi-Fermi level splitting (3)
- questions (3)
- radial flow (3)
- radio continuum: stars (3)
- radiocarbon dating (3)
- radiogenic isotopes (3)
- rainfall gradient (3)
- range dynamics (3)
- range of motion (3)
- range size (3)
- rate of torque development (3)
- reactance (3)
- reaction mechanisms (3)
- reading development (3)
- reading fluency (3)
- real options (3)
- real-time (3)
- rearrangement (3)
- recommendations (3)
- record linkage (3)
- recurrence analysis (3)
- recurrence quantification analysis (3)
- red meat (3)
- redox chemistry (3)
- redox regulation (3)
- reductase (3)
- reference material (3)
- referential choice (3)
- refinement (3)
- refugee (3)
- refugee youth (3)
- regime shifts (3)
- regional history (3)
- regionalisation (3)
- regioselectivity (3)
- regression tree (3)
- relationship constellations (3)
- relationships (3)
- relative rank (3)
- relaxation (3)
- remission (3)
- remote sensing data (3)
- remote teaching (3)
- replacement (3)
- representation learning (3)
- reproducing kernel Hilbert space (3)
- research framework (3)
- resolution (3)
- resonance energy-transfer (3)
- resurrection plants (3)
- reveals (3)
- reversible measure (3)
- reward (3)
- rhetoric (3)
- rhizosphere (3)
- right-wing populism (3)
- ring current (3)
- ring current electrons (3)
- risk attitudes (3)
- risk aversion (3)
- risk governance (3)
- risk management cycle (3)
- river (3)
- river floods (3)
- robbery (3)
- rock (3)
- rodent (3)
- role-play (3)
- rules (3)
- running mechanics (3)
- runoff generation (3)
- rural areas (3)
- rural development (3)
- sACC (3)
- salinity (3)
- salmonella (3)
- salt diffusion (3)
- sample preparation (3)
- sarcopenia (3)
- satellite data (3)
- scalability (3)
- scaled Brownian motion (3)
- scene perception (3)
- school development (3)
- schwarze Löcher (3)
- science (3)
- science mapping (3)
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- seawater (3)
- second language acquisition (3)
- second language processing (3)
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- secondary prevention (3)
- sedentary (3)
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- sediment dynamics (3)
- sediment routing (3)
- sedimentation (3)
- sediments (3)
- seed dispersal syndrome (3)
- seeds (3)
- segmentation (3)
- seismic monitoring (3)
- seismic risk (3)
- seismisches Rauschen (3)
- selenoprotein P (3)
- self threat (3)
- self-assembled monolayer (3)
- self-assembled monolayers (3)
- self-organisation (3)
- self-similarity (3)
- semantic (3)
- semi-parliamentarism (3)
- sensor data (3)
- sensorimotor control (3)
- sentence parsing (3)
- separation (3)
- separation of powers (3)
- serine cycle (3)
- serum (3)
- sex differences (3)
- sexual self-esteem (3)
- sexuality (3)
- shadow education (3)
- shallow structure hypothesis (3)
- shape-memory polymer (3)
- short-read mapping (3)
- sibilant (3)
- sickness absence (3)
- signalling (3)
- similarity (3)
- similarity-based interference (3)
- simulation model (3)
- simultaneous bilingualism (3)
- sin (3)
- singularity (3)
- situated processes (3)
- size distribution (3)
- skeletal muscle (3)
- skeletal robustness (3)
- skew Brownian motion (3)
- slope aspect (3)
- slum tourism (3)
- smart materials (3)
- soccer players (3)
- social environment (3)
- social integration (3)
- social network (3)
- social network analysis (3)
- social reactivity (3)
- social valuation (3)
- sociology of knowledge (3)
- sociometric status (3)
- sodium hydroxide etching (3)
- soft actuators (3)
- soft robotics (3)
- soil hydrology (3)
- soil landscape (3)
- soil texture (3)
- solar powered light-emitting diode (3)
- solubility (3)
- somatic variables (3)
- source parameters (3)
- sovereignty (3)
- soziale Integration (3)
- spatial scales (3)
- spatial turn (3)
- spatially explicit (3)
- spatially explicit model (3)
- speaking children (3)
- special education (3)
- species assembly (3)
- species composition (3)
- species recognition (3)
- specific developmental disorder (3)
- specific surface area (3)
- specificity (3)
- spectroelectrochemistry (3)
- sphingomyelin (3)
- sphingosine (3)
- sphingosine kinase (3)
- spider silk (3)
- spillover effects (3)
- spin (3)
- sportliche Leistung (3)
- stable states (3)
- star product (3)
- starch degradation (3)
- starch granule initiation (3)
- starch granule surface (3)
- starch granules (3)
- starch morphology (3)
- starch synthase (3)
- stars: (3)
- stars: coronae (3)
- stars: distances (3)
- stars: individual (WR 6) (3)
- stars: pre-main sequence (3)
- statins (3)
- statistical (3)
- statistical methods (3)
- stellar populations (3)
- stellar winds (3)
- stereoselectivity (3)
- stereotypes (3)
- stochastic bridge (3)
- stochastic processes (theory) (3)
- stochastic resetting (3)
- stochastic resonance (3)
- stochastische Prozesse (3)
- stokes shift (3)
- stopover (3)
- strategic management (3)
- strategic uncertainty (3)
- strategies (3)
- stress field (3)
- stress-gradient hypothesis (3)
- strike-slip fault (3)
- stroke rehabilitation (3)
- structural thermodynamics (3)
- student achievement (3)
- student exchange (3)
- study (3)
- study designs (3)
- subcellular localization (3)
- subjective well-being (3)
- submarine (3)
- substrate (3)
- succession (3)
- sufficiency (3)
- sulfotransferase (3)
- summer (3)
- sun (3)
- superoxide dismutase (3)
- supersaturated species coexistence (3)
- supervised machine learning (3)
- supramolecular chemistry (3)
- surface charge (3)
- surface electromyography (3)
- surface functionalization (3)
- surface treatment (3)
- surface-relief gratings (3)
- suspended sediments (3)
- sustainability science (3)
- sustainable consumption (3)
- sustainable fiscal policy (3)
- syllables (3)
- synchronization transition (3)
- synchrotron X-ray diffraction (3)
- syrphids (3)
- system analysis (3)
- tablet (3)
- tacit knowledge (3)
- talent identification (3)
- talk-in-interaction (3)
- tandem reaction (3)
- tandem reactions (3)
- tannic acid (3)
- task (3)
- task difficulty (3)
- tax administration (3)
- tax system (3)
- teaching and learning (3)
- teaching units (3)
- team sports (3)
- teamwork (3)
- technical advance (3)
- tele-TASK (3)
- teleconnections (3)
- telerehabilitation (3)
- telework (3)
- temperament (3)
- temperature dependence (3)
- temperature fluctuation (3)
- temperature variability (3)
- temporal dynamics (3)
- tetrabromidocuprate(II) (3)
- text analysis (3)
- text mining (3)
- texture (3)
- textures (3)
- thaw (3)
- theoretical chemistry (3)
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- thermal properties (3)
- thermo-responsive polymers (3)
- thermobarometry (3)
- thermoresponsive Polymere (3)
- thin-films (3)
- time averaging (3)
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- time-resolved luminescence (3)
- time-series analysis (3)
- timing (3)
- titania (3)
- titanium dioxide (3)
- total hip replacement (3)
- total knee replacement (3)
- tourmaline (3)
- trait convergence and divergence (3)
- trait emotional intelligence (3)
- trait variation (3)
- transcript (3)
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- treatment effects (3)
- trehalose 6-phosphate (3)
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- tropics (3)
- trunk muscle strength (3)
- trunk muscles (3)
- tunnel vision (3)
- twentieth century (3)
- type-III effector (3)
- ultrafast molecular dynamics (3)
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- uncanny valley (3)
- university teaching (3)
- untargeted metabolomics (3)
- upper mantle (3)
- use (3)
- user interaction (3)
- user types (3)
- user-generated content (3)
- value change (3)
- values (3)
- variance (3)
- varved lake sediments (3)
- varves (3)
- vascularization (3)
- vegetables (3)
- vegetation dynamics (3)
- venom (3)
- verb movement (3)
- violence in schools (3)
- virtualization (3)
- virtuelle Maschinen (3)
- virulence (3)
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- visual world paradigm (3)
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- vitamin E (3)
- voting (3)
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- winter wheat (3)
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- "Little Ice Age' (LIA) (2)
- "Medieval Warm Period' (MWP) (2)
- (Anti)aromaticity (2)
- (SEPE) factors (2)
- (dis)affiliation (2)
- (dis)agreement (2)
- (pronominal) resumption (2)
- ) (2)
- 0thers’ behavior (2)
- 1 (2)
- 1-Hydroxymethylpyren (2)
- 1-aminodecylidene bis-phosphonic acid (2)
- 1.5 degrees C (2)
- 11-mercaptoundecanoic acid (2)
- 16. Jahrhundert (2)
- 1799 (2)
- 1810-1813 (2)
- 1830 (2)
- 1831 (2)
- 1845-1862 (2)
- 1849 (2)
- 1970er Jahre (2)
- 1980s (2)
- 1D (2)
- 2 Different Strains (2)
- 2-Azaspiro[4.5]deca-1-ones (2)
- 2-deoxy-D-ribose-5-phoshphate aldolase (2)
- 2008 Wenchuan earthquake (2)
- 21st-Century (2)
- 24 h recall (2)
- 26D15 (2)
- 2D-LC-MS/MS (2)
- 2P cross section (2)
- 3-color fret (2)
- 3-mercaptopropionic acid (2)
- 31C20 (2)
- 35B09 (2)
- 35R02 (2)
- 39A12 (primary) (2)
- 3D geomechanical numerical model (2)
- 3D structure (2)
- 3D thermal model (2)
- 3D tissue model (2)
- 3D-Druck (2)
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- 4-nitrobenzenethiol (2)
- 454 pyrosequencing (2)
- 454-pyrosequencing (2)
- 47A52 (2)
- 5-day waves (2)
- 58E35 (secondary) (2)
- 6.5-Day wave (2)
- 65R20 (2)
- 65R32 (2)
- 78A46 (2)
- A-bar-movement (2)
- A. tenuissima (2)
- ABA (2)
- AC electroosmosis (2)
- ACINQ (2)
- ACWR (2)
- ADMET (2)
- AG (2)
- AIP1 (2)
- ALOS World 3D (2)
- AMD (2)
- AMOC (2)
- AMSTAR 2 (2)
- AOT bilayer (2)
- APC concentration gradient (2)
- APCI (2)
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The knowledge of the largest expected earthquake magnitude in a region is one of the key issues in probabilistic seismic hazard calculations and the estimation of worst-case scenarios. Earthquake catalogues are the most informative source of information for the inference of earthquake magnitudes. We analysed the earthquake catalogue for Central Asia with respect to the largest expected magnitudes m(T) in a pre-defined time horizon T-f using a recently developed statistical methodology, extended by the explicit probabilistic consideration of magnitude errors. For this aim, we assumed broad error distributions for historical events, whereas the magnitudes of recently recorded instrumental earthquakes had smaller errors. The results indicate high probabilities for the occurrence of large events (M >= 8), even in short time intervals of a few decades. The expected magnitudes relative to the assumed maximum possible magnitude are generally higher for intermediate-depth earthquakes (51-300 km) than for shallow events (0-50 km). For long future time horizons, for example, a few hundred years, earthquakes with M >= 8.5 have to be taken into account, although, apart from the 1889 Chilik earthquake, it is probable that no such event occurred during the observation period of the catalogue.
Earthquake catalogs are probably the most informative data source about spatiotemporal seismicity evolution. The catalog quality in one of the most active seismogenic zones in the world, Japan, is excellent, although changes in quality arising, for example, from an evolving network are clearly present. Here, we seek the best estimate for the largest expected earthquake in a given future time interval from a combination of historic and instrumental earthquake catalogs. We extend the technique introduced by Zoller et al. (2013) to estimate the maximum magnitude in a time window of length T-f for earthquake catalogs with varying level of completeness. In particular, we consider the case in which two types of catalogs are available: a historic catalog and an instrumental catalog. This leads to competing interests with respect to the estimation of the two parameters from the Gutenberg-Richter law, the b-value and the event rate lambda above a given lower-magnitude threshold (the a-value). The b-value is estimated most precisely from the frequently occurring small earthquakes; however, the tendency of small events to cluster in aftershocks, swarms, etc. violates the assumption of a Poisson process that is used for the estimation of lambda. We suggest addressing conflict by estimating b solely from instrumental seismicity and using large magnitude events from historic catalogs for the earthquake rate estimation. Applying the method to Japan, there is a probability of about 20% that the maximum expected magnitude during any future time interval of length T-f = 30 years is m >= 9.0. Studies of different subregions in Japan indicates high probabilities for M 8 earthquakes along the Tohoku arc and relatively low probabilities in the Tokai, Tonankai, and Nankai region. Finally, for scenarios related to long-time horizons and high-confidence levels, the maximum expected magnitude will be around 10.
We show how the maximum magnitude within a predefined future time horizon may be estimated from an earthquake catalog within the context of Gutenberg-Richter statistics. The aim is to carry out a rigorous uncertainty assessment, and calculate precise confidence intervals based on an imposed level of confidence a. In detail, we present a model for the estimation of the maximum magnitude to occur in a time interval T-f in the future, given a complete earthquake catalog for a time period T in the past and, if available, paleoseismic events. For this goal, we solely assume that earthquakes follow a stationary Poisson process in time with unknown productivity Lambda and obey the Gutenberg-Richter law in magnitude domain with unknown b-value. The random variables. and b are estimated by means of Bayes theorem with noninformative prior distributions. Results based on synthetic catalogs and on retrospective calculations of historic catalogs from the highly active area of Japan and the low-seismicity, but high-risk region lower Rhine embayment (LRE) in Germany indicate that the estimated magnitudes are close to the true values. Finally, we discuss whether the techniques can be extended to meet the safety requirements for critical facilities such as nuclear power plants. For this aim, the maximum magnitude for all times has to be considered. In agreement with earlier work, we find that this parameter is not a useful quantity from the viewpoint of statistical inference.
The injection of fluids is a well-known origin for the triggering of earthquake sequences. The growing number of projects related to enhanced geothermal systems, fracking, and others has led to the question, which maximum earthquake magnitude can be expected as a consequence of fluid injection? This question is addressed from the perspective of statistical analysis. Using basic empirical laws of earthquake statistics, we estimate the magnitude M-T of the maximum expected earthquake in a predefined future time window T-f. A case study of the fluid injection site at Paradox Valley, Colorado, demonstrates that the magnitude m 4.3 of the largest observed earthquake on 27 May 2000 lies very well within the expectation from past seismicity without adjusting any parameters. Vice versa, for a given maximum tolerable earthquake at an injection site, we can constrain the corresponding amount of injected fluids that must not be exceeded within predefined confidence bounds.
The Groningen gas field serves as a natural laboratory for production-induced earthquakes, because no earthquakes were observed before the beginning of gas production. Increasing gas production rates resulted in growing earthquake activity and eventually in the occurrence of the 2012M(w) 3.6 Huizinge earthquake. At least since this event, a detailed seismic hazard and risk assessment including estimation of the maximum earthquake magnitude is considered to be necessary to decide on the future gas production. In this short note, we first apply state-of-the-art methods of mathematical statistics to derive confidence intervals for the maximum possible earthquake magnitude m(max). Second, we calculate the maximum expected magnitude M-T in the time between 2016 and 2024 for three assumed gas-production scenarios. Using broadly accepted physical assumptions and 90% confidence level, we suggest a value of m(max) 4.4, whereas M-T varies between 3.9 and 4.3, depending on the production scenario.
In the present study, we summarize and evaluate the endeavors from recent years to estimate the maximum possible earthquake magnitude m(max) from observed data. In particular, we use basic and physically motivated assumptions to identify best cases and worst cases in terms of lowest and highest degree of uncertainty of m(max). In a general framework, we demonstrate that earthquake data and earthquake proxy data recorded in a fault zone provide almost no information about m(max) unless reliable and homogeneous data of a long time interval, including several earthquakes with magnitude close to m(max), are available. Even if detailed earthquake information from some centuries including historic and paleoearthquakes are given, only very few, namely the largest events, will contribute at all to the estimation of m(max), and this results in unacceptably high uncertainties. As a consequence, estimators of m(max) in a fault zone, which are based solely on earthquake-related information from this region, have to be dismissed.
Based on an analysis of continuous monitoring of farm animal behavior in the region of the 2016 M6.6 Norcia earthquake in Italy, Wikelski et al., 2020; (Seismol Res Lett, 89, 2020, 1238) conclude that animal activity can be anticipated with subsequent seismic activity and that this finding might help to design a "short-term earthquake forecasting method." We show that this result is based on an incomplete analysis and misleading interpretations. Applying state-of-the-art methods of statistics, we demonstrate that the proposed anticipatory patterns cannot be distinguished from random patterns, and consequently, the observed anomalies in animal activity do not have any forecasting power.
We present a Bayesian method that allows continuous updating the aperiodicity of the recurrence time distribution of large earthquakes based on a catalog with magnitudes above a completeness threshold. The approach uses a recently proposed renewal model for seismicity and allows the inclusion of magnitude uncertainties in a straightforward manner. Errors accounting for grouped magnitudes and random errors are studied and discussed. The results indicate that a stable and realistic value of the aperiodicity can be predicted in an early state of seismicity evolution, even though only a small number of large earthquakes has occurred to date. Furthermore, we demonstrate that magnitude uncertainties can drastically influence the results and can therefore not be neglected. We show how to correct for the bias caused by magnitude errors. For the region of Parkfield we find that the aperiodicity, or the coefficient of variation, is clearly higher than in studies which are solely based on the large earthquakes.
We investigate spatio-temporal properties of earthquake patterns in the San Jacinto fault zone (SJFZ), California, between Cajon Pass and the Superstition Hill Fault, using a long record of simulated seismicity constrained by available seismological and geological data. The model provides an effective realization of a large segmented strike-slip fault zone in a 3D elastic half-space, with heterogeneous distribution of static friction chosen to represent several clear step-overs at the surface. The simulated synthetic catalog reproduces well the basic statistical features of the instrumental seismicity recorded at the SJFZ area since 1981. The model also produces events larger than those included in the short instrumental record, consistent with paleo-earthquakes documented at sites along the SJFZ for the last 1,400 years. The general agreement between the synthetic and observed data allows us to address with the long-simulated seismicity questions related to large earthquakes and expected seismic hazard. The interaction between m a parts per thousand yen 7 events on different sections of the SJFZ is found to be close to random. The hazard associated with m a parts per thousand yen 7 events on the SJFZ increases significantly if the long record of simulated seismicity is taken into account. The model simulations indicate that the recent increased number of observed intermediate SJFZ earthquakes is a robust statistical feature heralding the occurrence of m a parts per thousand yen 7 earthquakes. The hypocenters of the m a parts per thousand yen 5 events in the simulation results move progressively towards the hypocenter of the upcoming m a parts per thousand yen 7 earthquake.
Kijko et al. (2016) present various methods to estimate parameters that are relevant for probabilistic seismic-hazard assessment. One of these parameters, although not the most influential, is the maximum possible earthquake magnitude m(max). I show that the proposed estimation of m(max) is based on an erroneous equation related to a misuse of the estimator in Cooke (1979) and leads to unstable results. So far, reported finite estimations of m(max) arise from data selection, because the estimator in Kijko et al. (2016) diverges with finite probability. This finding is independent of the assumed distribution of earthquake magnitudes. For the specific choice of the doubly truncated Gutenberg-Richter distribution, I illustrate the problems by deriving explicit equations. Finally, I conclude that point estimators are generally not a suitable approach to constrain m(max).
Extreme value statistics is a popular and frequently used tool to model the occurrence of large earthquakes. The problem of poor statistics arising from rare events is addressed by taking advantage of the validity of general statistical properties in asymptotic regimes. In this note, I argue that the use of extreme value statistics for the purpose of practically modeling the tail of the frequency-magnitude distribution of earthquakes can produce biased and thus misleading results because it is unknown to what degree the tail of the true distribution is sampled by data. Using synthetic data allows to quantify this bias in detail. The implicit assumption that the true M-max is close to the maximum observed magnitude M-max,M-observed restricts the class of the potential models a priori to those with M-max = M-max,M-observed + Delta M with an increment Delta M approximate to 0.5... 1.2. This corresponds to the simple heuristic method suggested by Wheeler (2009) and labeled :M-max equals M-obs plus an increment." The incomplete consideration of the entire model family for the frequency-magnitude distribution neglects, however, the scenario of a large so far unobserved earthquake.
The occurrence of earthquakes is characterized by a high degree of spatiotemporal complexity. Although numerous patterns, e.g. fore- and aftershock sequences, are well-known, the underlying mechanisms are not observable and thus not understood. Because the recurrence times of large earthquakes are usually decades or centuries, the number of such events in corresponding data sets is too small to draw conclusions with reasonable statistical significance. Therefore, the present study combines both, numerical modeling and analysis of real data in order to unveil the relationships between physical mechanisms and observational quantities. The key hypothesis is the validity of the so-called "critical point concept" for earthquakes, which assumes large earthquakes to occur as phase transitions in a spatially extended many-particle system, similar to percolation models. New concepts are developed to detect critical states in simulated and in natural data sets. The results indicate that important features of seismicity like the frequency-size distribution and the temporal clustering of earthquakes depend on frictional and structural fault parameters. In particular, the degree of quenched spatial disorder (the "roughness") of a fault zone determines whether large earthquakes occur quasiperiodically or more clustered. This illustrates the power of numerical models in order to identify regions in parameter space, which are relevant for natural seismicity. The critical point concept is verified for both, synthetic and natural seismicity, in terms of a critical state which precedes a large earthquake: a gradual roughening of the (unobservable) stress field leads to a scale-free (observable) frequency-size distribution. Furthermore, the growth of the spatial correlation length and the acceleration of the seismic energy release prior to large events is found. The predictive power of these precursors is, however, limited. Instead of forecasting time, location, and magnitude of individual events, a contribution to a broad multiparameter approach is encouraging.
Die vorliegende Arbeit beschäftigt sich mit der Charakterisierung von Seismizität anhand von Erdbebenkatalogen. Es werden neue Verfahren der Datenanalyse entwickelt, die Aufschluss darüber geben sollen, ob der seismischen Dynamik ein stochastischer oder ein deterministischer Prozess zugrunde liegt und was daraus für die Vorhersagbarkeit starker Erdbeben folgt. Es wird gezeigt, dass seismisch aktive Regionen häufig durch nichtlinearen Determinismus gekennzeichent sind. Dies schließt zumindest die Möglichkeit einer Kurzzeitvorhersage ein. Das Auftreten seismischer Ruhe wird häufig als Vorläuferphaenomen für starke Erdbeben gedeutet. Es wird eine neue Methode präsentiert, die eine systematische raumzeitliche Kartierung seismischer Ruhephasen ermöglicht. Die statistische Signifikanz wird mit Hilfe des Konzeptes der Ersatzdaten bestimmt. Als Resultat erhält man deutliche Korrelationen zwischen seismischen Ruheperioden und starken Erdbeben. Gleichwohl ist die Signifikanz dafür nicht hoch genug, um eine Vorhersage im Sinne einer Aussage über den Ort, die Zeit und die Stärke eines zu erwartenden Hauptbebens zu ermöglichen.
Paleoearthquakes and historic earthquakes are the most important source of information for the estimation of long-term earthquake recurrence intervals in fault zones, because corresponding sequences cover more than one seismic cycle. However, these events are often rare, dating uncertainties are enormous, and missing or misinterpreted events lead to additional problems. In the present study, I assume that the time to the next major earthquake depends on the rate of small and intermediate events between the large ones in terms of a clock change model. Mathematically, this leads to a Brownian passage time distribution for recurrence intervals. I take advantage of an earlier finding that under certain assumptions the aperiodicity of this distribution can be related to the Gutenberg-Richter b value, which can be estimated easily from instrumental seismicity in the region under consideration. In this way, both parameters of the Brownian passage time distribution can be attributed with accessible seismological quantities. This allows to reduce the uncertainties in the estimation of the mean recurrence interval, especially for short paleoearthquake sequences and high dating errors. Using a Bayesian framework for parameter estimation results in a statistical model for earthquake recurrence intervals that assimilates in a simple way paleoearthquake sequences and instrumental data. I present illustrative case studies from Southern California and compare the method with the commonly used approach of exponentially distributed recurrence times based on a stationary Poisson process.
Convergence of the frequency-magnitude distribution of global earthquakes - maybe in 200 years
(2013)
I study the ability to estimate the tail of the frequency-magnitude distribution of global earthquakes. While power-law scaling for small earthquakes is accepted by support of data, the tail remains speculative. In a recent study, Bell et al. (2013) claim that the frequency-magnitude distribution of global earthquakes converges to a tapered Pareto distribution. I show that this finding results from data fitting errors, namely from the biased maximum likelihood estimation of the corner magnitude theta in strongly undersampled models. In particular, the estimation of theta depends solely on the few largest events in the catalog. Taking this into account, I compare various state-of-the-art models for the global frequency-magnitude distribution. After discarding undersampled models, the remaining ones, including the unbounded Gutenberg-Richter distribution, perform all equally well and are, therefore, indistinguishable. Convergence to a specific distribution, if it ever takes place, requires about 200 years homogeneous recording of global seismicity, at least.
Downscaling of microfluidic cell culture and detection devices for electrochemical monitoring has mostly focused on miniaturization of the microfluidic chips which are often designed for specific applications and therefore lack functional flexibility. We present a compact microfluidic cell culture and electrochemical analysis platform with in-built fluid handling and detection, enabling complete cell based assays comprising on-line electrode cleaning, sterilization, surface functionalization, cell seeding, cultivation and electrochemical real-time monitoring of cellular dynamics. To demonstrate the versatility and multifunctionality of the platform, we explored amperometric monitoring of intracellular redox activity in yeast (Saccharomyces cerevisiae) and detection of exocytotically released dopamine from rat pheochromocytoma cells (PC12). Electrochemical impedance spectroscopy was used in both applications for monitoring cell sedimentation and adhesion as well as proliferation in the case of PC12 cells. The influence of flow rate on the signal amplitude in the detection of redox metabolism as well as the effect of mechanical stimulation on dopamine release were demonstrated using the programmable fluid handling capability. The here presented platform is aimed at applications utilizing cell based assays, ranging from e.g. monitoring of drug effects in pharmacological studies, characterization of neural stem cell differentiation, and screening of genetically modified microorganisms to environmental monitoring.
The paper studies catalytic super-Brownian motion on the real line, where the branching rate is controlled by a catalyst. D. A. Dawson, K. Fleischmann and S. Roelly showed, for a broad class of catalysts, that, as for constant branching, the processes are absolutely continuous measures. This paper considers a class of catalysts, called moderate, which must satisfy a uniform boundedness condition and a condition controlling the degree of singularity---essentially that the mass of catalyst in small balls should (uniformly) be of order r^a, where a>0. The main result of this paper shows that for this class of catalysts there is a continuous density field for the process. Moreover the density is the unique solution (in law) of an appropriate SPDE.
The author considers the heat equation in dimension one with singular drift and inhomogeneous space-time white noise. In particular, the quadratic variation measure of the white noise is not required to be absolutely continuous w.r.t. the Lebesgue measure, neither in space nor in time. Under some assumptions the author gives statements on strong and weak existence as well as strong and weak uniqueness of continuous solutions.
Hysteresis in the pinning-depinning transitions of spiral waves rotating around a hole in a circular shaped two- dimensional excitable medium is studied both by use of the continuation software AUTO and by direct numerical integration of the reaction-diffusion equations for the FitzHugh-Nagumo model. In order to clarify the role of different factors in this phenomenon, a kinematical description is applied. It is found that the hysteresis phenomenon computed for the reaction-diffusion model can be reproduced qualitatively only when a nonlinear eikonal equation (i.e. velocity- curvature relationship) is assumed. However, to obtain quantitative agreement, the dispersion relation has to be taken into account.
Sub-seasonal thaw slump mass wasting is not consistently energy limited at the landscape scale
(2018)
Predicting future thaw slump activity requires a sound understanding of the atmospheric drivers and geomorphic controls on mass wasting across a range of timescales. On sub-seasonal timescales, sparse measurements indicate that mass wasting at active slumps is often limited by the energy available for melting ground ice, but other factors such as rainfall or the formation of an insulating veneer may also be relevant. To study the sub-seasonal drivers, we derive topographic changes from single-pass radar interferometric data acquired by the TanDEM-X satellites. The estimated elevation changes at 12m resolution complement the commonly observed planimetric retreat rates by providing information on volume losses. Their high vertical precision (around 30 cm), frequent observations (11 days) and large coverage (5000 km(2)) allow us to track mass wasting as drivers such as the available energy change during the summer of 2015 in two study regions. We find that thaw slumps in the Tuktoyaktuk coastlands, Canada, are not energy limited in June, as they undergo limited mass wasting (height loss of around 0 cm day 1) despite the ample available energy, suggesting the widespread presence of early season insulating snow or debris veneer. Later in summer, height losses generally increase (around 3 cm day 1), but they do so in distinct ways. For many slumps, mass wasting tracks the available energy, a temporal pattern that is also observed at coastal yedoma cliffs on the Bykovsky Peninsula, Russia. However, the other two common temporal trajectories are asynchronous with the available energy, as they track strong precipitation events or show a sudden speed-up in late August respectively. The observed temporal patterns are poorly related to slump characteristics like the headwall height. The contrasting temporal behaviour of nearby thaw slumps highlights the importance of complex local and temporally varying controls on mass wasting.
Sub-seasonal thaw slump mass wasting is not consistently energy limited at the landscape scale
(2018)
Predicting future thaw slump activity requires a sound understanding of the atmospheric drivers and geomorphic controls on mass wasting across a range of timescales. On sub-seasonal timescales, sparse measurements indicate that mass wasting at active slumps is often limited by the energy available for melting ground ice, but other factors such as rainfall or the formation of an insulating veneer may also be relevant. To study the sub-seasonal drivers, we derive topographic changes from single-pass radar interferometric data acquired by the TanDEM-X satellites. The estimated elevation changes at 12m resolution complement the commonly observed planimetric retreat rates by providing information on volume losses. Their high vertical precision (around 30 cm), frequent observations (11 days) and large coverage (5000 km(2)) allow us to track mass wasting as drivers such as the available energy change during the summer of 2015 in two study regions. We find that thaw slumps in the Tuktoyaktuk coastlands, Canada, are not energy limited in June, as they undergo limited mass wasting (height loss of around 0 cm day 1) despite the ample available energy, suggesting the widespread presence of early season insulating snow or debris veneer. Later in summer, height losses generally increase (around 3 cm day 1), but they do so in distinct ways. For many slumps, mass wasting tracks the available energy, a temporal pattern that is also observed at coastal yedoma cliffs on the Bykovsky Peninsula, Russia. However, the other two common temporal trajectories are asynchronous with the available energy, as they track strong precipitation events or show a sudden speed-up in late August respectively. The observed temporal patterns are poorly related to slump characteristics like the headwall height. The contrasting temporal behaviour of nearby thaw slumps highlights the importance of complex local and temporally varying controls on mass wasting.
Necrotrophic as well as saprophytic small-spored Altemaria (A.) species are annually responsible for major losses of agricultural products, such as cereal crops, associated with the contamination of food and feedstuff with potential health-endangering Altemaria toxins. Knowledge of the metabolic capabilities of different species-groups to form mycotoxins is of importance for a reliable risk assessment. 93 Altemaria strains belonging to the four species groups Alternaria tenuissima, A. arborescens, A. altemata, and A. infectoria were isolated from winter wheat kernels harvested from fields in Germany and Russia and incubated under equal conditions. Chemical analysis by means of an HPLC-MS/MS multi-Alternaria-toxin-method showed that 95% of all strains were able to form at least one of the targeted 17 non-host specific Altemaria toxins. Simultaneous production of up to 15 (modified) Altemaria toxins by members of the A. tenuissima, A. arborescens, A. altemata species-groups and up to seven toxins by A. infectoria strains was demonstrated. Overall tenuazonic acid was the most extensively formed mycotoxin followed by alternariol and alternariol mono methylether, whereas altertoxin I was the most frequently detected toxin. Sulfoconjugated modifications of alternariol, alternariol mono methylether, altenuisol and altenuene were frequently determined. Unknown perylene quinone derivatives were additionally detected. Strains of the species-group A. infectoria could be segregated from strains of the other three species-groups due to significantly lower toxin levels and the specific production of infectopyrone. Apart from infectopyrone, alterperylenol was also frequently produced by 95% of the A. infectoria strains. Neither by the concentration nor by the composition of the targeted Altemaria toxins a differentiation between the species-groups A. altemata, A. tenuissima and A. arborescens was possible.
Necrotrophic as well as saprophytic small-spored Altemaria (A.) species are annually responsible for major losses of agricultural products, such as cereal crops, associated with the contamination of food and feedstuff with potential health-endangering Altemaria toxins. Knowledge of the metabolic capabilities of different species-groups to form mycotoxins is of importance for a reliable risk assessment. 93 Altemaria strains belonging to the four species groups Alternaria tenuissima, A. arborescens, A. altemata, and A. infectoria were isolated from winter wheat kernels harvested from fields in Germany and Russia and incubated under equal conditions. Chemical analysis by means of an HPLC-MS/MS multi-Alternaria-toxin-method showed that 95% of all strains were able to form at least one of the targeted 17 non-host specific Altemaria toxins. Simultaneous production of up to 15 (modified) Altemaria toxins by members of the A. tenuissima, A. arborescens, A. altemata species-groups and up to seven toxins by A. infectoria strains was demonstrated. Overall tenuazonic acid was the most extensively formed mycotoxin followed by alternariol and alternariol mono methylether, whereas altertoxin I was the most frequently detected toxin. Sulfoconjugated modifications of alternariol, alternariol mono methylether, altenuisol and altenuene were frequently determined. Unknown perylene quinone derivatives were additionally detected. Strains of the species-group A. infectoria could be segregated from strains of the other three species-groups due to significantly lower toxin levels and the specific production of infectopyrone. Apart from infectopyrone, alterperylenol was also frequently produced by 95% of the A. infectoria strains. Neither by the concentration nor by the composition of the targeted Altemaria toxins a differentiation between the species-groups A. altemata, A. tenuissima and A. arborescens was possible.
Alternaria (A.) is a genus of widespread fungi capable of producing numerous, possibly health-endangering Alternaria toxins (ATs), which are usually not the focus of attention. The formation of ATs depends on the species and complex interactions of various environmental factors and is not fully understood. In this study the influence of temperature (7 degrees C, 25 degrees C), substrate (rice, wheat kernels) and incubation time (4, 7, and 14 days) on the production of thirteen ATs and three sulfoconjugated ATs by three different Alternaria isolates from the species groups A. tenuissima and A. infectoria was determined. High-performance liquid chromatography coupled with tandem mass spectrometry was used for quantification. Under nearly all conditions, tenuazonic acid was the most extensively produced toxin. At 25 degrees C and with increasing incubation time all toxins were formed in high amounts by the two A. tenuissima strains on both substrates with comparable mycotoxin profiles. However, for some of the toxins, stagnation or a decrease in production was observed from day 7 to 14. As opposed to the A. tenuissima strains, the A. infectoria strain only produced low amounts of ATs, but high concentrations of stemphyltoxin III. The results provide an essential insight into the quantitative in vitro AT formation under different environmental conditions, potentially transferable to different field and storage conditions.
Spotlight on the underdogs
(2017)
Alternaria (A.) is a genus of widespread fungi capable of producing numerous, possibly health-endangering Alternaria toxins (ATs), which are usually not the focus of attention. The formation of ATs depends on the species and complex interactions of various environmental factors and is not fully understood. In this study the influence of temperature (7 °C, 25 °C), substrate (rice, wheat kernels) and incubation time (4, 7, and 14 days) on the production of thirteen ATs and three sulfoconjugated ATs by three different Alternaria isolates from the species groups A. tenuissima and A. infectoria was determined. High-performance liquid chromatography coupled with tandem mass spectrometry was used for quantification. Under nearly all conditions, tenuazonic acid was the most extensively produced toxin. At 25 °C and with increasing incubation time all toxins were formed in high amounts by the two A. tenuissima strains on both substrates with comparable mycotoxin profiles. However, for some of the toxins, stagnation or a decrease in production was observed from day 7 to 14. As opposed to the A. tenuissima strains, the A. infectoria strain only produced low amounts of ATs, but high concentrations of stemphyltoxin III. The results provide an essential insight into the quantitative in vitro AT formation under different environmental conditions, potentially transferable to different field and storage conditions
We recently demonstrated that the sympathetic nervous system can be voluntarily activated following a training program consisting of cold exposure, breathing exercises, and meditation. This resulted in profound attenuation of the systemic inflammatory response elicited by lipopolysaccharide (LPS) administration. Herein, we assessed whether this training program affects the plasma metabolome and if these changes are linked to the immunomodulatory effects observed. A total of 224 metabolites were identified in plasma obtained from 24 healthy male volunteers at six timepoints, of which 98 were significantly altered following LPS administration. Effects of the training program were most prominent shortly after initiation of the acquired breathing exercises but prior to LPS administration, and point towards increased activation of the Cori cycle. Elevated concentrations of lactate and pyruvate in trained individuals correlated with enhanced levels of anti-inflammatory interleukin (IL)-10. In vitro validation experiments revealed that co-incubation with lactate and pyruvate enhances IL-10 production and attenuates the release of pro-inflammatory IL-1 beta and IL-6 by LPS-stimulated leukocytes. Our results demonstrate that practicing the breathing exercises acquired during the training program results in increased activity of the Cori cycle. Furthermore, this work uncovers an important role of lactate and pyruvate in the anti-inflammatory phenotype observed in trained subjects.
We recently demonstrated that the sympathetic nervous system can be voluntarily activated following a training program consisting of cold exposure, breathing exercises, and meditation. This resulted in profound attenuation of the systemic inflammatory response elicited by lipopolysaccharide (LPS) administration. Herein, we assessed whether this training program affects the plasma metabolome and if these changes are linked to the immunomodulatory effects observed. A total of 224 metabolites were identified in plasma obtained from 24 healthy male volunteers at six timepoints, of which 98 were significantly altered following LPS administration. Effects of the training program were most prominent shortly after initiation of the acquired breathing exercises but prior to LPS administration, and point towards increased activation of the Cori cycle. Elevated concentrations of lactate and pyruvate in trained individuals correlated with enhanced levels of anti-inflammatory interleukin (IL)-10. In vitro validation experiments revealed that co-incubation with lactate and pyruvate enhances IL-10 production and attenuates the release of pro-inflammatory IL-1 beta and IL-6 by LPS-stimulated leukocytes. Our results demonstrate that practicing the breathing exercises acquired during the training program results in increased activity of the Cori cycle. Furthermore, this work uncovers an important role of lactate and pyruvate in the anti-inflammatory phenotype observed in trained subjects.
During hopping an early burst can be observed in the EMG from the soleus muscle starting about 45 ms after touch-down. It may be speculated that this early EMG burst is a stretch reflex response superimposed on activity from a supra-spinal origin. We hypothesised that if a stretch reflex indeed contributes to the early EMG burst, then advancing or delaying the touch-down without the subject's knowledge should similarly advance or delay the burst. This was indeed the case when touch-down was advanced or delayed by shifting the height of a programmable platform up or down between two hops and this resulted in a correspondent shift of the early EMG burst. Our second hypothesis was that the motor cortex contributes to the first EMG burst during hopping. If so, inhibition of the motor cortex would reduce the magnitude of the burst. By applying a low-intensity magnetic stimulus it was possible to inhibit the motor cortex and this resulted in a suppression of the early EMG burst. These results suggest that sensory feedback and descending drive from the motor cortex are integrated to drive the motor neuron pool during the early EMG burst in hopping. Thus, simple reflexes work in concert with higher order structures to produce this repetitive movement.
Unlike for other retroviruses, only a few host cell factors that aid the replication of foamy viruses (FVs) via interaction with viral structural components are known. Using a yeast-two-hybrid (Y2H) screen with prototype FV (PFV) Gag protein as bait we identified human polo-like kinase 2 (hPLK2), a member of cell cycle regulatory kinases, as a new interactor of PFV capsids. Further Y2H studies confirmed interaction of PFV Gag with several PLKs of both human and rat origin. A consensus Ser-Thr/Ser-Pro (S-T/S-P) motif in Gag, which is conserved among primate FVs and phosphorylated in PFV virions, was essential for recognition by PLKs. In the case of rat PLK2, functional kinase and polo-box domains were required for interaction with PFV Gag. Fluorescently-tagged PFV Gag, through its chromatin tethering function, selectively relocalized ectopically expressed eGFP-tagged PLK proteins to mitotic chromosomes in a Gag STP motif-dependent manner, confirming a specific and dominant nature of the Gag-PLK interaction in mammalian cells. The functional relevance of the Gag-PLK interaction was examined in the context of replication-competent FVs and single-round PFV vectors. Although STP motif mutated viruses displayed wild type (wt) particle release, RNA packaging and intra-particle reverse transcription, their replication capacity was decreased 3-fold in single-cycle infections, and up to 20-fold in spreading infections over an extended time period. Strikingly similar defects were observed when cells infected with single-round wt Gag PFV vectors were treated with a pan PLK inhibitor. Analysis of entry kinetics of the mutant viruses indicated a post-fusion defect resulting in delayed and reduced integration, which was accompanied with an enhanced preference to integrate into heterochromatin. We conclude that interaction between PFV Gag and cellular PLK proteins is important for early replication steps of PFV within host cells.
Unlike for other retroviruses, only a few host cell factors that aid the replication of foamy viruses (FVs) via interaction with viral structural components are known. Using a yeast-two-hybrid (Y2H) screen with prototype FV (PFV) Gag protein as bait we identified human polo-like kinase 2 (hPLK2), a member of cell cycle regulatory kinases, as a new interactor of PFV capsids. Further Y2H studies confirmed interaction of PFV Gag with several PLKs of both human and rat origin. A consensus Ser-Thr/Ser-Pro (S-T/S-P) motif in Gag, which is conserved among primate FVs and phosphorylated in PFV virions, was essential for recognition by PLKs. In the case of rat PLK2, functional kinase and polo-box domains were required for interaction with PFV Gag. Fluorescently-tagged PFV Gag, through its chromatin tethering function, selectively relocalized ectopically expressed eGFP-tagged PLK proteins to mitotic chromosomes in a Gag STP motif-dependent manner, confirming a specific and dominant nature of the Gag-PLK interaction in mammalian cells. The functional relevance of the Gag-PLK interaction was examined in the context of replication-competent FVs and single-round PFV vectors. Although STP motif mutated viruses displayed wild type (wt) particle release, RNA packaging and intra-particle reverse transcription, their replication capacity was decreased 3-fold in single-cycle infections, and up to 20-fold in spreading infections over an extended time period. Strikingly similar defects were observed when cells infected with single-round wt Gag PFV vectors were treated with a pan PLK inhibitor. Analysis of entry kinetics of the mutant viruses indicated a post-fusion defect resulting in delayed and reduced integration, which was accompanied with an enhanced preference to integrate into heterochromatin. We conclude that interaction between PFV Gag and cellular PLK proteins is important for early replication steps of PFV within host cells.
We present a theoretical framework for the analysis of the statistical properties of thermal fluctuations on a lossy transmission line. A quantization scheme of the electrical signals in the transmission line is formulated. We discuss two applications in detail. Noise spectra at finite temperature for voltage and current are shown to deviate significantly from the Johnson-Nyquist limit, and they depend on the position on the transmission line. We analyze the spontaneous emission, at low temperature, of a Rydberg atom and its resonant enhancement due to vacuum fluctuations in a capacitively coupled transmission line. The theory can also be applied to study the performance of microscale and nanoscale devices, including high-resolution sensors and quantum information processors
We present a momentum transfer mechanism mediated by electromagnetic fields that originates in a system of two nearby molecules: one excited (donor D*) and the other in ground state (acceptor A). An intermolecular force related to fluorescence resonant energy or Forster transfer (FRET) arises in the unstable D* A molecular system, which differs from the equilibrium van der Waals interaction. Due to the its finite lifetime, a mechanical impulse is imparted to the relative motion in the system. We analyze the FRET impulse when the molecules are embedded in free space and find that its magnitude can be much greater than the single recoil photon momentum, getting comparable with the thermal momentum (Maxwell-Boltzmann distribution) at room temperature. In addition, we propose that this FRET impulse can be exploited in the generation of acoustic waves inside a film containing layers of donor and acceptor molecules, when a picosecond laser pulse excites the donors. This acoustic transient is distinguishable from that produced by thermal stress due to laser absorption, and may therefore play a role in photoacoustic spectroscopy. The effect can be seen as exciting a vibrating system like a string or organ pipe with light; it may be used as an opto-mechanical transducer.
Home range size and resource use of breeding and non-breeding white storks along a land use gradient
(2018)
Biotelemetry is increasingly used to study animal movement at high spatial and temporal resolution and guide conservation and resource management. Yet, limited sample sizes and variation in space and habitat use across regions and life stages may compromise robustness of behavioral analyses and subsequent conservation plans. Here, we assessed variation in (i) home range sizes, (ii) home range selection, and (iii) fine-scale resource selection of white storks across breeding status and regions and test model transferability. Three study areas were chosen within the Central German breeding grounds ranging from agricultural to fluvial and marshland. We monitored GPS-locations of 62 adult white storks equipped with solar-charged GPS/3D-acceleration (ACC) transmitters in 2013-2014. Home range sizes were estimated using minimum convex polygons. Generalized linear mixed models were used to assess home range selection and fine-scale resource selection by relating the home ranges and foraging sites to Corine habitat variables and normalized difference vegetation index in a presence/pseudo-absence design. We found strong variation in home range sizes across breeding stages with significantly larger home ranges in non-breeding compared to breeding white storks, but no variation between regions. Home range selection models had high explanatory power and well predicted overall density of Central German white stork breeding pairs. Also, they showed good transferability across regions and breeding status although variable importance varied considerably. Fine-scale resource selection models showed low explanatory power. Resource preferences differed both across breeding status and across regions, and model transferability was poor. Our results indicate that habitat selection of wild animals may vary considerably within and between populations, and is highly scale dependent. Thereby, home range scale analyses show higher robustness whereas fine-scale resource selection is not easily predictable and not transferable across life stages and regions. Such variation may compromise management decisions when based on data of limited sample size or limited regional coverage. We thus recommend home range scale analyses and sampling designs that cover diverse regional landscapes and ensure robust estimates of habitat suitability to conserve wild animal populations.
Models are useful tools for understanding and predicting ecological patterns and processes. Under ongoing climate and biodiversity change, they can greatly facilitate decision-making in conservation and restoration and help designing adequate management strategies for an uncertain future. Here, we review the use of spatially explicit models for decision support and to identify key gaps in current modelling in conservation and restoration. Of 650 reviewed publications, 217 publications had a clear management application and were included in our quantitative analyses. Overall, modelling studies were biased towards static models (79%), towards the species and population level (80%) and towards conservation (rather than restoration) applications (71%). Correlative niche models were the most widely used model type. Dynamic models as well as the gene-to-individual level and the community-to-ecosystem level were underrepresented, and explicit cost optimisation approaches were only used in 10% of the studies. We present a new model typology for selecting models for animal conservation and restoration, characterising model types according to organisational levels, biological processes of interest and desired management applications. This typology will help to more closely link models to management goals. Additionally, future efforts need to overcome important challenges related to data integration, model integration and decision-making. We conclude with five key recommendations, suggesting that wider usage of spatially explicit models for decision support can be achieved by 1) developing a toolbox with multiple, easier-to-use methods, 2) improving calibration and validation of dynamic modelling approaches and 3) developing best-practise guidelines for applying these models. Further, more robust decision-making can be achieved by 4) combining multiple modelling approaches to assess uncertainty, and 5) placing models at the core of adaptive management. These efforts must be accompanied by long-term funding for modelling and monitoring, and improved communication between research and practise to ensure optimal conservation and restoration outcomes.
Models are useful tools for understanding and predicting ecological patterns and processes. Under ongoing climate and biodiversity change, they can greatly facilitate decision-making in conservation and restoration and help designing adequate management strategies for an uncertain future. Here, we review the use of spatially explicit models for decision support and to identify key gaps in current modelling in conservation and restoration. Of 650 reviewed publications, 217 publications had a clear management application and were included in our quantitative analyses. Overall, modelling studies were biased towards static models (79%), towards the species and population level (80%) and towards conservation (rather than restoration) applications (71%). Correlative niche models were the most widely used model type. Dynamic models as well as the gene-to-individual level and the community-to-ecosystem level were underrepresented, and explicit cost optimisation approaches were only used in 10% of the studies. We present a new model typology for selecting models for animal conservation and restoration, characterising model types according to organisational levels, biological processes of interest and desired management applications. This typology will help to more closely link models to management goals. Additionally, future efforts need to overcome important challenges related to data integration, model integration and decision-making. We conclude with five key recommendations, suggesting that wider usage of spatially explicit models for decision support can be achieved by 1) developing a toolbox with multiple, easier-to-use methods, 2) improving calibration and validation of dynamic modelling approaches and 3) developing best-practise guidelines for applying these models. Further, more robust decision-making can be achieved by 4) combining multiple modelling approaches to assess uncertainty, and 5) placing models at the core of adaptive management. These efforts must be accompanied by long-term funding for modelling and monitoring, and improved communication between research and practise to ensure optimal conservation and restoration outcomes.
SDM performance varied for different range dynamics. Prediction accuracies decreased when abrupt range shifts occurred as species were outpaced by the rate of climate change, and increased again when a new equilibrium situation was realised. When ranges contracted, prediction accuracies increased as the absences were predicted well. Far- dispersing species were faster in tracking climate change, and were predicted more accurately by SDMs than short- dispersing species. BRTs mostly outperformed GLMs. The presence of a predator, and the inclusion of its incidence as an environmental predictor, made BRTs and GLMs perform similarly. Results are discussed in light of other studies dealing with effects of ecological traits and processes on SDM performance. Perspectives are given on further advancements of SDMs and for possible interfaces with more mechanistic approaches in order to improve predictions under environmental change.
Empirical species distribution models (SDMs) constitute often the tool of choice for the assessment of rapid climate change effects on species vulnerability. Conclusions regarding extinction risks might be misleading, however, because SDMs do not explicitly incorporate dispersal or other demographic processes. Here, we supplement SDMs with a dynamic population model 1) to predict climate-induced range dynamics for black grouse in Switzerland, 2) to compare direct and indirect measures of extinction risks, and 3) to quantify uncertainty in predictions as well as the sources of that uncertainty. To this end, we linked models of habitat suitability to a spatially explicit, individual-based model. In an extensive sensitivity analysis, we quantified uncertainty in various model outputs introduced by different SDM algorithms, by different climate scenarios and by demographic model parameters. Potentially suitable habitats were predicted to shift uphill and eastwards. By the end of the 21st century, abrupt habitat losses were predicted in the western Prealps for some climate scenarios. In contrast, population size and occupied area were primarily controlled by currently negative population growth and gradually declined from the beginning of the century across all climate scenarios and SDM algorithms. However, predictions of population dynamic features were highly variable across simulations. Results indicate that inferring extinction probabilities simply from the quantity of suitable habitat may underestimate extinction risks because this may ignore important interactions between life history traits and available habitat. Also, in dynamic range predictions uncertainty in SDM algorithms and climate scenarios can become secondary to uncertainty in dynamic model components. Our study emphasises the need for principal evaluation tools like sensitivity analysis in order to assess uncertainty and robustness in dynamic range predictions. A more direct benefit of such robustness analysis is an improved mechanistic understanding of dynamic species responses to climate change.
Data limitations can lead to unrealistic fits of predictive species distribution models (SDMs) and spurious extrapolation to novel environments. Here, we want to draw attention to novel combinations of environmental predictors that are within the sampled range of individual predictors but are nevertheless outside the sample space. These tend to be overlooked when visualizing model behaviour. They may be a cause of differing model transferability and environmental change predictions between methods, a problem described in some studies but generally not well understood. We here use a simple simulated data example to illustrate the problem and provide new and complementary visualization techniques to explore model behaviour and predictions to novel environments. We then apply these in a more complex real-world example. Our results underscore the necessity of scrutinizing model fits, ecological theory and environmental novelty.
Density regulation influences population dynamics through its effects on demographic rates and consequently constitutes a key mechanism explaining the response of organisms to environmental changes. Yet, it is difficult to establish the exact form of density dependence from empirical data. Here, we developed an individual-based model to explore how resource limitation and behavioural processes determine the spatial structure of white stork Ciconia ciconia populations and regulate reproductive rates. We found that the form of density dependence differed considerably between landscapes with the same overall resource availability and between home range selection strategies, highlighting the importance of fine-scale resource distribution in interaction with behaviour. In accordance with theories of density dependence, breeding output generally decreased with density but this effect was highly variable and strongly affected by optimal foraging strategy, resource detection probability and colonial behaviour. Moreover, our results uncovered an overlooked consequence of density dependence by showing that high early nestling mortality in storks, assumed to be the outcome of harsh weather, may actually result from density dependent effects on food provision. Our findings emphasize that accounting for interactive effects of individual behaviour and local environmental factors is crucial for understanding density-dependent processes within spatially structured populations. Enhanced understanding of the ways animal populations are regulated in general, and how habitat conditions and behaviour may dictate spatial population structure and demographic rates is critically needed for predicting the dynamics of populations, communities and ecosystems under changing environmental conditions.
Ecologists carry a well-stocked toolbox with a great variety of sampling methods, statistical analyses and modelling tools, and new methods are constantly appearing. Evaluation and optimisation of these methods is crucial to guide methodological choices. Simulating error-free data or taking high-quality data to qualify methods is common practice. Here, we emphasise the methodology of the 'virtual ecologist' (VE) approach where simulated data and observer models are used to mimic real species and how they are 'virtually' observed. This virtual data is then subjected to statistical analyses and modelling, and the results are evaluated against the 'true' simulated data. The VE approach is an intuitive and powerful evaluation framework that allows a quality assessment of sampling protocols, analyses and modelling tools. It works under controlled conditions as well as under consideration of confounding factors such as animal movement and biased observer behaviour. In this review, we promote the approach as a rigorous research tool, and demonstrate its capabilities and practical relevance. We explore past uses of VE in different ecological research fields, where it mainly has been used to test and improve sampling regimes as well as for testing and comparing models, for example species distribution models. We discuss its benefits as well as potential limitations, and provide some practical considerations for designing VE studies. Finally, research fields are identified for which the approach could be useful in the future. We conclude that VE could foster the integration of theoretical and empirical work and stimulate work that goes far beyond sampling methods, leading to new questions, theories, and better mechanistic understanding of ecological systems.
Species respond to environmental change by dynamically adjusting their geographical ranges. Robust predictions of these changes are prerequisites to inform dynamic and sustainable conservation strategies. Correlative species distribution models (SDMs) relate species’ occurrence records to prevailing environmental factors to describe the environmental niche. They have been widely applied in global change context as they have comparably low data requirements and allow for rapid assessments of potential future species’ distributions. However, due to their static nature, transient responses to environmental change are essentially ignored in SDMs. Furthermore, neither dispersal nor demographic processes and biotic interactions are explicitly incorporated. Therefore, it has often been suggested to link statistical and mechanistic modelling approaches in order to make more realistic predictions of species’ distributions for scenarios of environmental change. In this thesis, I present two different ways of such linkage. (i) Mechanistic modelling can act as virtual playground for testing statistical models and allows extensive exploration of specific questions. I promote this ‘virtual ecologist’ approach as a powerful evaluation framework for testing sampling protocols, analyses and modelling tools. Also, I employ such an approach to systematically assess the effects of transient dynamics and ecological properties and processes on the prediction accuracy of SDMs for climate change projections. That way, relevant mechanisms are identified that shape the species’ response to altered environmental conditions and which should hence be considered when trying to project species’ distribution through time. (ii) I supplement SDM projections of potential future habitat for black grouse in Switzerland with an individual-based population model. By explicitly considering complex interactions between habitat availability and demographic processes, this allows for a more direct assessment of expected population response to environmental change and associated extinction risks. However, predictions were highly variable across simulations emphasising the need for principal evaluation tools like sensitivity analysis to assess uncertainty and robustness in dynamic range predictions. Furthermore, I identify data coverage of the environmental niche as a likely cause for contrasted range predictions between SDM algorithms. SDMs may fail to make reliable predictions for truncated and edge niches, meaning that portions of the niche are not represented in the data or niche edges coincide with data limits. Overall, my thesis contributes to an improved understanding of uncertainty factors in predictions of range dynamics and presents ways how to deal with these. Finally I provide preliminary guidelines for predictive modelling of dynamic species’ response to environmental change, identify key challenges for future research and discuss emerging developments.
Persönlichkeitspsychologisch fundierte Studienorientierung durch onlinebasierte Self-Assessments
(2019)
מחקר זה עוסק במשנתו החדשנית של ר' צדוק הכהן מלובלין. לפי רוב החוקרים, ר' צדוק ממשיך את משנת רבו, ר' מרדכי יוסף ליינער מאיזביצה, ומציג פטליזם אקזיסטנציאליסטי: לאדם יש חופש כנגד החוק המקובל, לפי רצון האל הנגלה בליבו, אפילו בתשוקותיו, החורג מההלכה; ואולם, האדם אינו קובע את הרצון המתגלה בשורש נשמתו, אלא חושפו בלבד. בכתבי ר' צדוק ניתן למצוא ביטויים רבים, בתוכן ובצורה, לפטליזם זה; עם זאת, הוא מציג גם התבטאויות רבות בדבר הבחירה האנושית החופשית וכוחה היצירתי לכונן ולקבוע את שורשו של האדם, ולחדש ולהשפיע על העולמות האלוקיים ועל העולם-הזה. מחקר זה מתמקד בקטעים אלו שמרכזיותם הוזנחה במחקר עד כה, ומכאן הבנתו המחודשת במשנתו.
את עמדת ר' צדוק ניתן להסביר באמצעות התפיסה הפרדוקסלית, הטוענת לכוחם המלא של שני הקטבים הסותרים ואף להשפעה הדדית ביניהם, היוצרת מתח קשה אך פורה: בניגוד לתהליך הפורמלי, האניטלקטואלי והאפריורי של הפטליזם, שבו 'הידיעה' האלוהית מבטלת את 'הבחירה' האנושית החופשית, ר' צדוק מציג פטאליות, המזהה המציאות עצמה את הידיעה והרצון האלוהיים המצויים בכל. בפטליות זו הידיעה אינה מבטלת את הבחירה; להיפך: ללא הידיעה האלוקית אין לאף דבר קיום, ולכן רק מציאות הידיעה בבחירה היא המאפשרת את קיומה הממשי.
תפיסתו האונטולוגית של ר' צדוק מתקיימת לא רק בתוכן הישיר של דבריו, אלא גם בעקיפין, באופן דרשנותו ובמובן שהוא מעניק למושגים שבהם הוא דן; לכן, הפטליות מתגלה גם בתחומים נוספים, שבהם מצוי פער בין הממד המוחלט וההכרחי ('ידיעה') לממד הקונטינגנטי, הארעי והיחסי ('בחירה'): השקר, הדמיון, הרוע, החטא, הייסורים ועוד, אמנם קונטינגנטיים ויחסיים לעומת מוחלטות האמת, הטוב וכו'; אך לפי ר' צדוק, האל רוצה בהם ככאלה – כלומר יש להם ממשות שאינה מוחלטת, אלא ממשות ככאלה, כקונטינגנטיים. אך ממשות זו אינה מאשרת אותם כפי שהם, אלא יוצרת בהם-עצמם טרנספורמציה. למשל, הרוע אינו הופך לטוב מוחלט או נותר כרוע, אלא הופך ל'טוב מאד' שלפי ר' צדוק גדול מהטוב הרגיל.
מכאן עולה גם ההשפעה ההפוכה, זו של הבחירה על הידיעה. לפי ר' צדוק, משקבלה הקונטינגנטיות והיחסיות של 'הבחירה' – שהיא למעשה מהות הבריאה ומהות האדם ומעשיו – את ממשותה, בכוחה אף להוסיף כביכול על המוחלטות האלוקית הקבועה של 'הידיעה': 'נגע' החטא או הייסורים הופך בעצמו, בחילוף אותם אותיות, ל'ענג' הגדול מההנאה הרגילה; בכוח האדם להשפיע על העולמות העליונים בגזירת גזירות ובביטול גזירות אלוקיות; בכוחו אף להשפיע על העולם-הזה, בחידושו היומיומי על-ידי חידושי התושב"ע, ובקידוש החודש המסוגל לשנות את תנועת המזלות השמימיים. מצד אחד, היצירתיות האנושית של חידושי התושב"ע כלולה באמת האלוקית הגנוזה בתושב"כ האלוקית והיא רק חושפת אותה; אך לפי ר"צ, מצד אחר מתברר שמקור חידושי התושב"ע דווקא גבוה ממקור התושב"כ והם אלו היוצרים וקובעים אותה.
ר' צדוק מציג שני מושגים מרכזיים לפרדוקס שלו: בממד האונטולוגי – 'הייחוד הגמור' של האל, שבו הדואליות הקונטינגנטית (בין האל לנבראיו, והבחירה שהיא מאפשרת) של 'הייחוד התחתון' מתקיימת פרדוקסלית עם האחדות המוחלטת ו'הידיעה' האלוהית של 'הייחוד העליון'.
בממד של מצבו האקזיסטנציאלי של האדם – 'השורש הנעלם': בניגוד לר' מרדכי יוסף רבו, ר' צדוק טוען שהאדם קובע את גורלו על-ידי מעשיו הבחיריים והקונטינגנטיים; ואולם, במקביל, בדומה לרבו, הוא טוען גם שהשורש הקבוע של האדם נקבע על-ידי 'הידיעה' האלוהית והיא זו הקובעת את מעשיו לטוב או למוטב. אך מעל אלו מציג ר' צדוק שורש נוסף, 'נעלם' הגבוה מהשורש הקבוע: הוא אכן שורש מוחלט ('ידיעה'), אך הוא נקבע ומכוּנן על-ידי מעשיו הבחיריים של האדם, בדומה לבריאה האלוהית 'יש מאין'.
The ability of some plant species to dominate communities in new biogeographical ranges has been attributed to an innate higher competitive ability and release from co-evolved specialist enemies. Specifically, invasive success in the new range might be explained by release from biotic negative soil-feedbacks, which control potentially dominant species in their native range. To test this hypothesis, we grew individuals from sixteen phylogenetically paired European grassland species that became either invasive or naturalized in new ranges, in either sterilized soil or in sterilized soil with unsterilized soil inoculum from their native home range. We found that although the native members of invasive species generally performed better than those of naturalized species, these native members of invasive species also responded more negatively to native soil inoculum than did the native members of naturalized species. This supports our hypothesis that potentially invasive species in their native range are held in check by negative soil-feedbacks. However, contrary to expectation, negative soil-feedbacks in potentially invasive species were not much increased by interspecific competition. There was no significant variation among families between invasive and naturalized species regarding their feedback response (negative vs. neutral). Therefore, we conclude that the observed negative soil feedbacks in potentially invasive species may be quite widespread in European families of typical grassland species.
Bacterial molybdoenzymes are key enzymes involved in the global sulphur, nitrogen and carbon cycles. These enzymes require the insertion of the molybdenum cofactor (Moco) into their active sites and are able to catalyse a large range of redox-reactions. Escherichia coli harbours nineteen different molybdoenzymes that require a tight regulation of their synthesis according to substrate availability, oxygen availability and the cellular concentration of molybdenum and iron. The synthesis and assembly of active molybdoenzymes are regulated at the level of transcription of the structural genes and of translation in addition to the genes involved in Moco biosynthesis. The action of global transcriptional regulators like FNR, NarXL/QP, Fur and ArcA and their roles on the expression of these genes is described in detail. In this review we focus on what is known about the molybdenum- and iron-dependent regulation of molybdoenzyme and Moco biosynthesis genes in the model organism E. coli. The gene regulation in E. coli is compared to two other well studied model organisms Rhodobacter capsulatus and Shewanella oneidensis.