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"Gewalt an Schulen" ist ein emotional besetztes Thema in der öffentlichen Diskussion. Umso notwendiger ist eine sachliche und empirisch fundierte Auseinandersetzung. Das Buch gibt einen Überblick über Ausmaß, Erscheinungsformen und Ursachen von Gewalt und Mobbing an Schulen sowie über Möglichkeiten der Prävention bzw. Intervention. Es verbindet systematisch die Analyse der schulischen Gewaltphänomene mit Ansätzen der Gewaltprävention bzw. -intervention. Ein Schwerpunkt liegt dabei auf den schulischen Präventions- und Interventionsprogrammen, die einer kritischen Bewertung unterzogen werden. Der interdisziplinär angelegte Band, der Erkenntnisse der Erziehungswissenschaft, Psychologie und Soziologie integriert, verknüpft Ergebnisse der Gewaltforschung mit Anforderungen an eine moderne Präventionsarbeit im Kontext einer Schul- und Bildungsreform.
In many biological and environmental applications spatially resolved sensing of molecular oxygen is desirable. A powerful tool for distributed measurements is optical time domain reflectometry (OTDR) which is often used in the field of telecommunications. We combine this technique with a novel optical oxygen sensor dye, triangular-[4] phenylene (TP), immobilized in a polymer matrix. The TP luminescence decay time is 86 ns. The short decay time of the sensor dye is suitable to achieve a spatial resolution of some meters. In this paper we present the development and characterization of a reflectometer in the UV range of the electromagnetic spectrum as well as optical oxygen sensing with different fiber arrangements.
When playing violent video games, aggressive actions are performed against the background of an originally neutral environment, and associations are formed between cues related to violence and contextual features. This experiment examined the hypothesis that neutral contextual features of a virtual environment become associated with aggressive meaning and acquire the function of primes for aggressive cognitions. Seventy-six participants were assigned to one of two violent video game conditions that varied in context (ship vs. city environment) or a control condition. Afterwards, they completed a Lexical Decision Task to measure the accessibility of aggressive cognitions in which they were primed either with ship-related or city-related words. As predicted, participants who had played the violent game in the ship environment had shorter reaction times for aggressive words following the ship primes than the city primes, whereas participants in the city condition responded faster to the aggressive words following the city primes compared to the ship primes. No parallel effect was observed for the non-aggressive targets. The findings indicate that the associations between violent and neutral cognitions learned during violent game play facilitate the accessibility of aggressive cognitions.
When playing violent video games, aggressive actions are performed against the background of an originally neutral environment, and associations are formed between cues related to violence and contextual features. This experiment examined the hypothesis that neutral contextual features of a virtual environment become associated with aggressive meaning and acquire the function of primes for aggressive cognitions. Seventy-six participants were assigned to one of two violent video game conditions that varied in context (ship vs. city environment) or a control condition. Afterwards, they completed a Lexical Decision Task to measure the accessibility of aggressive cognitions in which they were primed either with ship-related or city-related words. As predicted, participants who had played the violent game in the ship environment had shorter reaction times for aggressive words following the ship primes than the city primes, whereas participants in the city condition responded faster to the aggressive words following the city primes compared to the ship primes. No parallel effect was observed for the non-aggressive targets. The findings indicate that the associations between violent and neutral cognitions learned during violent game play facilitate the accessibility of aggressive cognitions.
Various 1,6- and 1,8-naphthalenophanes were synthesized by using the Photo-Dehydro-Diels-Alder (PDDA) reaction of bis-ynones. These compounds are easily accessible from omega-(3-iodophenyl)carboxylic acids in three steps. The obtained naphthalenophanes are axially chiral and the activation barrier for the atropisomerization could be determined in some cases by means of dynamic NMR (DNMR) and/or dynamic HPLC (DHPLC) experiments.
Qualitative Forschung leistet mit einem differenzierten Methodenrepertoire einen zentralen Beitrag zur Empirie in der Erziehungswissenschaft. Das Handbuch führt umfassend in das breite Spektrum qualitativer Forschungszugänge ein.
Der erste Teil bietet eine grundlegende Einführung in qualitative Forschung, reflektiert ihre Bedeutung und Erkenntnispotentiale, zeichnet historische Entwicklungen nach und legt theoretische Grundlagen dar. Der zweite Teil stellt die wichtigsten methodischen Forschungskonzeptionen qualitativer erziehungswissenschaftlicher Forschung vor. Der dritte Teil führt in Strategien für Erhebungen und Auswertungen ein. Die Aufsätze des vierten Teils widmen sich dem forschenden Umgang mit visuellen Quellen und Medien. Der fünfte Teil stellt eine Auswahl gegenstandsbezogener qualitativer Forschungsansätze vor. Abschließend folgen Ansätze der Praxis-, Aktions- und Handlungsforschung und nützliche Informationen und Hinweise für die Planung und Durchführung von Forschungsvorhaben.
Das Handbuch richtet sich an Promovierende, Forschende, Lehrende und Studierende in den Erziehungs- und Sozialwissenschaften. Es bietet Pädagoginnen und Pädagogen Informationen über Methoden systematischer Praxisforschung und trägt damit zur Stärkung und Innovation qualitativer Forschungszugänge und zur Weiterentwicklung der methodischen Standards bei.
Forschende Lernwerkstatt
(2013)
Background: DNA fragments carrying internal recognition sites for the restriction endonucleases intended for cloning into a target plasmid pose a challenge for conventional cloning.
Results: A method for directional insertion of DNA fragments into plasmid vectors has been developed. The target sequence is amplified from a template DNA sample by PCR using two oligonucleotides each containing a single deoxyinosine base at the third position from the 5' end. Treatment of such PCR products with endonuclease V generates 3' protruding ends suitable for ligation with vector fragments created by conventional restriction endonuclease reactions.
Conclusions: The developed approach generates terminal cohesive ends without the use of Type II restriction endonucleases, and is thus independent from the DNA sequence. Due to PCR amplification, minimal amounts of template DNA are required. Using the robust Taq enzyme or a proofreading Pfu DNA polymerase mutant, the method is applicable to a broad range of insert sequences. Appropriate primer design enables direct incorporation of terminal DNA sequence modifications such as tag addition, insertions, deletions and mutations into the cloning strategy. Further, the restriction sites of the target plasmid can be either retained or removed.
The dynamics of external contributions to the geomagnetic field is investigated by applying time-frequency methods to magnetic observatory data. Fractal models and multiscale analysis enable obtaining maximum quantitative information related to the short-term dynamics of the geomagnetic field activity. The stochastic properties of the horizontal component of the transient external field are determined by searching for scaling laws in the power spectra. The spectrum fits a power law with a scaling exponent β, a typical characteristic of self-affine time-series. Local variations in the power-law exponent are investigated by applying wavelet analysis to the same time-series. These analyses highlight the self-affine properties of geomagnetic perturbations and their persistence. Moreover, they show that the main phases of sudden storm disturbances are uniquely characterized by a scaling exponent varying between 1 and 3, possibly related to the energy contained in the external field. These new findings suggest the existence of a long-range dependence, the scaling exponent being an efficient indicator of geomagnetic activity and singularity detection. These results show that by using magnetogram regularity to reflect the magnetosphere activity, a theoretical analysis of the external geomagnetic field based on local power-law exponents is possible.
In this paper, we determine necessary and sufficient conditions for Bruck-Reilly and generalized Bruck-Reilly ∗-extensions of arbitrary monoids to be regular, coregular and strongly π-inverse. These semigroup classes have applications in various field of mathematics, such as matrix theory, discrete mathematics and p-adic analysis (especially in operator theory). In addition, while regularity and coregularity have so many applications in the meaning of boundaries (again in operator theory), inverse monoids and Bruck-Reilly extensions contain a mixture fixed-point results of algebra, topology and geometry within the purposes of this journal.
The genetic code is degenerate; thus, protein evolution does not uniquely determine the coding sequence. One of the puzzles in evolutionary genetics is therefore to uncover evolutionary driving forces that result in specific codon choice. In many bacteria, the first 5-10 codons of protein-coding genes are often codons that are less frequently used in the rest of the genome, an effect that has been argued to arise from selection for slowed early elongation to reduce ribosome traffic jams. However, genome analysis across many species has demonstrated that the region shows reduced mRNA folding consistent with pressure for efficient translation initiation. This raises the possibility that unusual codon usage is a side effect of selection for reduced mRNA structure. Here we discriminate between these two competing hypotheses, and show that in bacteria selection favours codons that reduce mRNA folding around the translation start, regardless of whether these codons are frequent or rare. Experiments confirm that primarily mRNA structure, and not codon usage, at the beginning of genes determines the translation rate.
TRAPID
(2013)
Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise. Here, we present TRAPID, an online tool for the fast and efficient processing of assembled RNA-Seq transcriptome data, developed to mitigate these challenges. TRAPID offers high-throughput open reading frame detection, frameshift correction and includes a functional, comparative and phylogenetic toolbox, making use of 175 reference proteomes. Benchmarking and comparison against state-of-the-art transcript analysis tools reveals the efficiency and unique features of the TRAPID system. TRAPID is freely available at http://bioinformatics.psb.ugent.be/webtools/trapid/.
Growing out of the crisis
(2013)
Greece’s currently planned institutional reforms will help to get the country going with limited economic growth. With an economy based primarily on tourism, trade, and agriculture, Greece lacks an established competitive industry and an innovation-friendly environment, resulting in a low export ratio given the small size of the country and its long-time EU-membership. Instead, Greece exports only its nation's talent, with low returns. To become prosperous, the country must better capitalize on its Eurozone membership and add innovative sectors to its economic structure. Given Greece's hidden assets, such as the attractiveness of the country, a small number of strong research centers and an impressive diaspora in research, finance and business, we envision a Greek “Silicon Valley” and propose a ten point policy plan to achieve that goal.
Background: The linear noise approximation (LNA) is commonly used to predict how noise is regulated and exploited at the cellular level. These predictions are exact for reaction networks composed exclusively of first order reactions or for networks involving bimolecular reactions and large numbers of molecules. It is however well known that gene regulation involves bimolecular interactions with molecule numbers as small as a single copy of a particular gene. It is therefore questionable how reliable are the LNA predictions for these systems.
Results: We implement in the software package intrinsic Noise Analyzer (iNA), a system size expansion based method which calculates the mean concentrations and the variances of the fluctuations to an order of accuracy higher than the LNA. We then use iNA to explore the parametric dependence of the Fano factors and of the coefficients of variation of the mRNA and protein fluctuations in models of genetic networks involving nonlinear protein degradation, post-transcriptional, post-translational and negative feedback regulation. We find that the LNA can significantly underestimate the amplitude and period of noise-induced oscillations in genetic oscillators. We also identify cases where the LNA predicts that noise levels can be optimized by tuning a bimolecular rate constant whereas our method shows that no such regulation is possible. All our results are confirmed by stochastic simulations.
Conclusion: The software iNA allows the investigation of parameter regimes where the LNA fares well and where it does not. We have shown that the parametric dependence of the coefficients of variation and Fano factors for common gene regulatory networks is better described by including terms of higher order than LNA in the system size expansion. This analysis is considerably faster than stochastic simulations due to the extensive ensemble averaging needed to obtain statistically meaningful results. Hence iNA is well suited for performing computationally efficient and quantitative studies of intrinsic noise in gene regulatory networks.
Research indicates that evidence-based policy making is most successful when public administrators refer to diversified information portfolios. With the rising prominence of social media in the last decade, this paper argues that governments can benefit from integrating this publically available, user-generated data through the technique of social media analytics (SMA). There are already several initiatives set up to predict future policy issues, e.g. for the policy fields of crisis mitigation or migrant integration insights. The authors analyse these endeavours and their potential for providing more efficient and effective public policies. Furthermore, they scrutinise the challenges to governmental SMA usage in particular with regards to legal and ethical aspects. Reflecting the latter, this paper provides forward-looking recommendations on how these technologies can best be used for future policy making in a legally and ethically sound manner.
Zeitgeschichte als eine spezifische historische Reflexionsform der Gegenwart gewinnt in der Umbruchsphase um 1800 eine neue Qualität. Sie ist Ausdruck von politisch-ökonomischen Beschleunigungserfahrungen und von sich verändernden medialen Konstellationen. Ihr Thema sind die großen globalen Finanzkrisen, Revolutionen und geopolitischen Konflikte; ihr Feld der Zwischenbereich von Geschichtsschreibung und Journalismus. Zeithistoriker bewegen sich nicht im akademischen Elfenbeinturm, sondern sie suchen ein breites Publikum ebenso wie die Nähe zu den politischen Entscheidungsträgern. Dennoch wird Zeitgeschichte als eine Erkenntnisform jenseits der bloßen Tagespolitik verstanden. Als Wissenschaft des sozialen Wandels steht sie in der Tradition des Geschichtsdenkens der Aufklärung und weist zugleich voraus auf die Historismus-Kritik des Vormärz. In dieser Studie werden Akteure, Medien, europäische Pressenetzwerke, Wissensformen und Diskurse der so umschriebenen Zeitgeschichtsschreibung exemplarisch rekonstruiert. Im Zentrum steht dabei Friedrich Buchholz (1768-1843). Erstmals veröffentlicht werden in einem Quellenanhang Buchholz` Briefe an seinen Verleger Johann Friedrich Cotta aus den Jahren 1805-1833, die ein anschauliches Dokument sowohl der politischen Situation dieser Zeit als auch der Marktbedingungen der neuen Öffentlichkeitsformen darstellen.
Portal alumni
(2013)
Begonnen hat es um 1900 mit Qualitätskontrolle, später folgte Qualitätsprüfung und seit Mitte der 90er Jahre hat das Thema Qualitätsmanagement Einzug gehalten in alle Bereiche von Politik und Gesellschaft. Im Gesundheitswesen, der Justiz und auch an vielen Hochschulen wurden spezielle Stellen eingerichtet, die sich gezielt mit der Umsetzung von Qualitätsentwicklung oder Qualitätsmanagement befassen. Das übergeordnete Ziel bei Einführung eines Qualitätsmanagements ist es, die Wettbewerbsfähigkeit der Organisation sowie auch die Zufriedenheit der Mitglieder der Institutionen und weiterer Stakeholder zu steigern, indem die Qualität der Tätigkeiten und der jeweiligen Rahmenbedingungen erhalten und optimiert wird. Mit der bewussten Entscheidung zur Qualitätssicherung und -entwicklung beginnt ein fortlaufender Prozess, der stetig intensiv begleitet werden muss. Qualitätsmanagement wirkt nachhaltig, in dem durch die Schaffung regelmäßiger und systematischer Strukturen und Prozesse auch zukünftig den beteiligten Personen ein optimales Handeln entsprechend der dann geltenden Bedingungen ermöglicht wird. Portal alumni widmet sich in seinem zehnten Heft diesem Thema und hat Absolventen der Universität Potsdam nach ihrem Tätigkeitsfeld im Qualitätsmanagement und den entsprechenden Erfolgen befragt. Dabei zeigt sich, dass Ehemalige Einsatzbereiche in Wirtschaft und Unternehmen aber auch in Sport, Bildung oder Hochschulen gefunden haben. Daneben berichten wir in diesem Heft von einem Projekt des Career Service, dem Schnupperjobben, und auch die Berichte über die Geschehnisse an Ihrer Alma mater kommen nicht zu kurz.
Background: With increasing age neuromuscular deficits (e.g., sarcopenia) may result in impaired physical performance and an increased risk for falls. Prominent intrinsic fall-risk factors are age-related decreases in balance and strength / power performance as well as cognitive decline. Additional studies are needed to develop specifically tailored exercise programs for older adults that can easily be implemented into clinical practice. Thus, the objective of the present trial is to assess the effects of a fall prevention program that was developed by an interdisciplinary expert panel on measures of balance, strength / power, body composition, cognition, psychosocial well-being, and falls self-efficacy in healthy older adults. Additionally, the time-related effects of detraining are tested.
Methods/Design: Healthy old people (n = 54) between the age of 65 to 80 years will participate in this trial. The testing protocol comprises tests for the assessment of static / dynamic steady-state balance (i.e., Sharpened Romberg Test, instrumented gait analysis), proactive balance (i.e., Functional Reach Test; Timed Up and Go Test), reactive balance (i.e., perturbation test during bipedal stance; Push and Release Test), strength (i.e., hand grip strength test; Chair Stand Test), and power (i.e., Stair Climb Power Test; countermovement jump). Further, body composition will be analysed using a bioelectrical impedance analysis system. In addition, questionnaires for the assessment of psychosocial (i.e., World Health Organisation Quality of Life Assessment-Bref), cognitive (i.e., Mini Mental State Examination), and fall risk determinants (i.e., Fall Efficacy Scale -International) will be included in the study protocol. Participants will be randomized into two intervention groups or the control / waiting group. After baseline measures, participants in the intervention groups will conduct a 12-week balance and strength / power exercise intervention 3 times per week, with each training session lasting 30 min. (actual training time). One intervention group will complete an extensive supervised training program, while the other intervention group will complete a short version (` 3 times 3') that is home-based and controlled by weekly phone calls. Post-tests will be conducted right after the intervention period. Additionally, detraining effects will be measured 12 weeks after program cessation. The control group / waiting group will not participate in any specific intervention during the experimental period, but will receive the extensive supervised program after the experimental period.
Discussion: It is expected that particularly the supervised combination of balance and strength / power training will improve performance in variables of balance, strength / power, body composition, cognitive function, psychosocial well-being, and falls self-efficacy of older adults. In addition, information regarding fall risk assessment, dose-response-relations, detraining effects, and supervision of training will be provided. Further, training-induced health-relevant changes, such as improved performance in activities of daily living, cognitive function, and quality of life, as well as a reduced risk for falls may help to lower costs in the health care system. Finally, practitioners, therapists, and instructors will be provided with a scientifically evaluated feasible, safe, and easy-to-administer exercise program for fall prevention.
Deutsche Universitäten erweitern ihre E-Learning-Angebote als Service für die Studierenden und Lehrenden. Diese sind je nach Fakultät unterschiedlich ausgeprägt. Dieser Artikel zeigt, wie durch technische Erweiterung der Infrastruktur, einer Anpassung der Organisationsstruktur und einer gezielten Inhaltsentwicklung eine durchgängige und personalisierbare Lehr- und Lernumgebung (Personal Learning Environment, PLE) geschaffen und damit die Akzeptanz bei den Lehrenden und Studierenden für E-Learning erhöht werden kann. Aus der vorausgehenden, systematischen Anforderungsanalyse können Kennzahlen für die Qualitätssicherung von E-Learning-Angeboten abgeleitet werden.
Portal Wissen = Borders
(2013)
The new edition of the Potsdam Research Magazine “Portal Wissen” approaches the subject “Borders” from different perspectives.
As a linguist, this headline makes me think of linguistic borders and the effects that might result from the contact of two languages at a particular border. There is, for instance, ample evidence of code-switching, i.e. the use of material from at least two languages in a single utterance. The reasons for code-switching can be manifold. On the one hand, code-switching may result from a limited language competence, for example if a speaker lacks a particular word in a nonnative language. On the other hand, code-switching may be a matter of prestige if the speaker wants to demonstrate his or her affiliation to a certain social group by switching languages. If code-switching does not only occur sporadically but involves whole language communities over a longer period of time, it can result in significant changes of the involved languages. Which language “gives” and which one “takes” is determined by sociolinguistic factors. It is, hence, quite easy to predict that German varieties spoken in language islands in South and Eastern Europe as well as in North and Latin America will absorb more and more language material from their neighbouring languages until they disappear unless political will strives to preserve these language varieties. Increasing mobility of modern societies has multiplied the extent and the intensity of language contact and certainly comprises a large number of different contact situations besides the one most commonly known, i.e. the contact between German and English.
From a historic point of view, German witnesses a strong influence of various Romance languages such as Latin, French and Italian. In Potsdam, one cannot help being reminded of the French influence during the 18th century.
Overcoming language borders becomes also apparent in the everyday life of an international research university. In March this year, the Annual Conference of the German Linguistic Society took place in Potsdam, with more than 500 participants. Lingua franca of this conference was English. Compared to previous conferences, this further increased the number of international participants.
The articles in this edition illustrate various approaches to the topic “Borders”: On the trail of “Boundary Surveys”, we follow the Australian explorer Ludwig Leichhardt. “Travellers Across Borders” is focussed on articles dealing with the literature of the colonial Caribbean or with the work of an Italian geologist deep beneath the earth’s surface, for example. Looking for the “Boundless”, our authors follow scientists who discuss questions like “Why love hurts?”. The present issue of “Portal Wissen” also takes into account “Drawing Up Borders” in an article that is concerned with the limits of workrelated stress. Instances of successful “Border Crossing” are provided by the “Handkerchief Lab” as well as by new biotechnological applications.
I would like to wish you inspiring border experiences, hoping that you will get many impulses for crossing professional borders in your field of expertise.
Prof. Ulrike Demske
Professor of the History and the Varieties of the German Language
Vice President International Affairs, Alumni and Fundraising
Portal Wissen = Layers
(2013)
The latest edition of our Potsdam Research Magazine “Portal Wissen” addresses the topic “Layers” in many different ways. Geoscientists often deal with layers: layers of soil, sediment, or rock are the evidence of repeated and long-lasting processes of erosion and sedimentation that took place in the early history of the earth. For instance, mountains are eroded by water, ice and wind. The sand that results from that erosion might eventually form a new layer on the ocean floor known as a sediment horizon. After tens of millions of years, tectonic plate movements can deform the ocean floor, pushing it upwards as mountains are created, bringing the layers of sand from former mountain chains together with fossilized sea dwellers into the realm of climbers and mountaineers – a fundamental cycle within the Earth system that was succinctly described by Ibn Sina nearly 1000 years ago, and later by Charles Darwin when he was crossing the Andes.
The landscape around us overlays the products of recent processes with those from the past. Slow processes or extreme events that happen very rarely – like floods, earthquakes or rockslides – wipe out certain characteristics, while others remain on the surface. In this sense, the landscape is like a palimpsest – a piece of parchment that monks in the Middle Ages scraped clean again and again to write something new. Analysing rock layers and soil is similar to the work of a detective. Geophysical deep sounding with sound and radar waves, precise measurements of motions related to earthquakes, and deep boreholes each provide a glimpse of the characteristics of what lies beneath us, giving us a better understanding of spatial distribution of the various layers. Fossils can tell us the age of a layer of sediment, while radiometric isotopes in minerals reveal how quickly a rock moved from deep within the Earth up to the surface, perhaps during the process of mountain building. Thin layers of ash tell us when there was a devastating volcanic eruption that influenced environmental conditions. The shape, gradation, and surface conditions of sand grains reflect whether wind or water was responsible for their transport. We know, for instance, that northern Germany was a desert landscape more than 260 million years ago. At that time, the wind made huge dunes migrate across the region. Over time, climate and vegetation slowly alter the physical and chemical characteristics of sand and rock at the surface, turning them into soil, the epidermis of our planet. Mineralogical analyses of layers of the soil layer tell us whether the climate was dry or wet. These kinds of observations allow us to reconstruct links between our climate system and processes that have taken place on the Earth’s surface, as well as those processes that originate at much deeper levels. The clues we use might be hidden under the surface of the earth or clearly visible on the surface, like in the mountains, or even in freshly cut rock alongside roads.
On the following pages, we invite you to accompany scientists from Potsdam into their world of research. They track hidden traces of longgone earthquakes in the Tien Shan Mountains; they discover ancient forms of life in deep-sea sediments. They even examine layers in outer space that can tell us something about the formation of planets. “Portal Wissen” not only presents scientists of the University of Potsdam who deal with the sequence of layers formed by solid rock, but also those scientists who deal with levels of education or social strata. Research scientists explain how to implement the social mission of inclusion in teaching, and how pupils from the Berlin district Kreuzberg examine language in urban neighbourhoods together with students from the University of Potsdam.
Although these types of “layers” are very different, they all have something in common. Their structure and profile are evidence of continuously changing conditions. The present will leave traces and layers that future geoscientists will measure and examine. We already speak of the Anthropocene, a geological era dominated by humans, which is characterized by far-reaching changes in erosion and sedimentation rates, and the displacement of natural habitats. I hope that you will discover exciting and inspiring stories in this edition. And remember – it is always worth having a look beneath the surface.
Prof. Manfred Strecker, PHD
Professor of Geology
Portal Wissen = Grenzen
(2013)
Die neue Ausgabe des Potsdamer Forschungsmagazins widmet sich dem Thema „Grenzen“ aus unterschiedlichsten Perspektiven.
Als Sprachwissenschaftlerin denke ich bei diesem Stichwort an sprachliche Grenzen und die Wirkungen, die sich aus dem Kontakt von zwei Sprachen an einer Sprachgrenze ergeben können. Vielfältig sind die Belege für das sogenannte Code-Switching, dem Wechsel von einer Sprache in die andere in einer bestimmten Äußerungssituation. Die Motive für einen solchen Sprachwechsel können ganz unterschiedlicher Natur sein: So lässt sich Code-Switching einerseits auf eine eingeschränkte sprachliche Kompetenz zurückführen, wenn beispielsweise einer Sprecherin ein bestimmtes Wort in der Zweitsprache fehlt, andererseits kann das Code-Switching prestigebedingt sein, wenn ein Sprecher durch einen sprachlichen Wechsel seine Zugehörigkeit zu einer bestimmten gesellschaftlichen Gruppe demonstrieren möchte.
Wenn Code-Switching nicht nur punktuell stattfindet, sondern ganze Sprach- gemeinschaften über einen längeren Zeitraum erfasst, kann es zu weitreichenden Veränderungen der betroffenen Sprachen kommen. Welche Sprache „gibt“ und welche Sprache „nimmt“, hängt von sprachexternen Faktoren ab. So ist es ein Leichtes vorherzusagen, dass die deutschen Varietäten der Sprachinseln in Süd- und Osteuropa wie auch in Nord- und Südamerika wohl zunehmend Material und Muster aus den sie umgebenden Sprachen aufnehmen und letztendlich in ihnen aufgehen werden, wenn sie nicht durch politischen Willen konserviert werden. Das Ausmaß von Sprachkontakt ist mit der zunehmenden räumlichen Mobilität moderner Gesellschaften stark angestiegen, und lässt sich sicher nicht auf den aktuell immer wieder thematisierten Sprachkontakt des Deutschen mit dem Englischen reduzieren. Historisch gesehen ist das Deutsche vor allem durch die romanischen Sprachen stark geprägt worden – in Potsdam denkt man hier unwillkürlich an den starken Einfluss des Französischen im 18. Jahrhundert.
Die Überwindung sprachlicher Grenzen zeigt sich auch im Alltag einer international ausgerichteten Forschungsuniversität: So hat im März dieses Jahres in Potsdam die Jahrestagung der deutschen Gesellschaft für Sprachwissenschaft mit über 500 Teilnehmern stattgefunden. Lingua Franca der Tagung war Englisch, was den Anteil der internationalen Teilnehmer gegenüber früheren Jahrestagungen nochmals vergrößert hat.
Zahlreiche andere Zugänge zum Thema Grenzen bieten die Beiträger dieser Ausgabe des Forschungsmagazins: Auf den Spuren von „Grenzvermessungen“ bewegen sich die Texte zum Australienforscher Ludwig Leichhardt oder zur Energiebilanz im Spitzensport. „Grenzgänger“ stehen im Fokus der Beiträge über eine Forschergruppe zur Literatur der kolonialen Karibik oder die tief in die Erde reichenden Forschungen eines italienischen Geologen. Auf der Suche nach dem „Grenzenlosen“ folgen die Autoren den Wissenschaftlern etwa zur Frage „Why love hurts?“ oder hinein in eine Geschichte des Musikhörens. Den umgekehrten Weg, nämlich „Grenzziehungen“, beobachtet „Portal Wissen“ in der Arbeit des Potsdamer MenschenRechtsZentrums oder den Auswertungen des Nationalen Dopingpräventionsplans. Belege für erfolgreiche „Grenzüberschreitungen“ liefern schließlich Blicke ins „Taschentuchlabor“ oder die digitale Edition mittelalterlicher Prosaepen, um nur einige Beiträge aus diesem Heft herauszugreifen.
Ich wünsche Ihnen bei der Lektüre anregende Grenzerfahrungen mit vielen Impulsen für eigene fachliche Grenzüberschreitungen.
Prof. Dr. Ulrike Demske
Professorin für Geschichte und Variation der Deutschen Sprache
Vizepräsidentin für Internationales, Alumni und Fundraising
Portal Wissen = Schichten
(2013)
Die neue Ausgabe unseres Potsdamer Forschungsmagazins widmet sich ganz und gar und auf sehr unterschiedliche Weise dem Thema „Schichten“.
Als Geowissenschaftler begegnen mir Schichten häufig: Boden-, Sedimentoder Gesteinsschichten – sie sind das Zeugnis lang anhaltender und immer wiederkehrender Erosionsund Ablagerungsprozesse, wie sie schon in der frühen Erdgeschichte stattfanden. Gebirge werden beispielsweise durch Wasser, Eis und Wind erodiert. Die Erosionsprodukte bilden vielleicht irgendwann auf dem Meeresgrund als Ablagerungshorizont eine neue Schicht. Umgekehrt führen Deformationsprozesse als Folge von tektonischen Plattenbewegungen dazu, dass Gebirge entstehen und der Mensch versteinerte Meeresbewohner in verfalteten Sedimentschichten im Hochgebirge findet – Beziehungen, wie sie bereits von Ibn Sina und später von Charles Darwin bei seiner Andenüberquerung beschrieben wurden. Aber auch die Landschaft, die wir bei einem Blick aus dem Fenster wahrnehmen, ist nichts anderes als das Produkt verschiedener Überlagerungen von Prozessen Liebe Leserinnen und Leser, in der Vergangenheit und heute. Langsam ablaufende Prozesse oder seltener stattfindende Extremereignisse wie Fluten, Erdbeben oder Bergstürze – einzelne Merkmale werden dabei ausgelöscht, andere treten zutage. Ähnlich einem Palimpsest – einem Stück Pergament, das die Mönche im Mittelalter immer wieder abgeschabt und neu überschrieben haben. Die Analyse von Gesteins- und Bodenschichten gleicht der Arbeit eines Detektivs. Geophysikalische Tiefensondierungen mit Schall- und Radarwellen, die genaue Vermessung von Erdbebenherden oder Tiefbohrungen bringen uns verdeckte Erdschichten näher. Fossilienfunde und radiometrische Datierungen verraten das Alter einer Schicht. Mithilfe dünner Ascheschichten können wir nachweisen, wann verheerende Vulkanausbrüche Umweltbedingungen beeinflusst haben.
Böden, die Epidermis unseres Planeten, spiegeln die Eigenschaften der darunterliegenden Gesteinsschichten, der Vegetationsbedeckung oder den Einfluss des Klimas wider. Die Form, Sortierung und Oberflächenbeschaffenheit von Sandkörnern lassen uns erkennen, ob Wind oder Wasser für ihren Transport gesorgt haben. So wissen wir, dass Norddeutschland vor über 260 Millionen Jahren eine Wüstenlandschaft war, in der der Wind mächtige Dünen wandern ließ. Die mineralogische Untersuchung damit verbundener Schichten verrät, ob das Klima trocken oder feucht war. So dechiffrieren wir Hinweise auf vergangene Prozesse, die unter der Erdoberfläche versteckt sind oder – wie etwa in Gebirgen – offen zutage treten.
Auf den kommenden Seiten laden wir Sie ein, Potsdamer Wissenschaftler an die Orte ihrer Forschung zu begleiten: Im Tien Shan-Gebirge spüren sie längst vergangene Erdbeben auf, in Tiefseesedimenten entdecken sie uralte Lebensformen und im Weltall erforschen sie gar Schichten, die uns etwas über die Entstehung von Planeten verraten. Die Wissenschaftler der Universität Potsdam beschränken sich allerdings nicht auf die Schichtabfolgen der festen Erde. „Portal Wissen“ blickt auch jenen Wissenschaftlern über die Schulter, die sich mit „Bildungsschichten“ oder „Gesellschaftsschichten“ befassen. So erklären Forscher, wie der gesellschaftliche Auftrag der Inklusion in der Lehre umgesetzt wird oder wie Kreuzberger Schüler zusammen mit Potsdamer Studierenden Sprache im urbanen Raum erforschen.
So unterschiedlich sie sind, eines ist allen diesen „Schichten“ gemeinsam: Ihre Struktur und Form sind Zeugnis sich immer wieder verändernder Rahmenbedingungen. Auch die Gegenwart wird Spuren und Schichten hinterlassen, die zukünftige Erdwissenschaftler vermessen und untersuchen werden. Schon jetzt spricht man vom Anthropozän, einem vom Menschen dominierten geologischen Zeitabschnitt, charakterisiert durch tiefgreifende Änderungen in den Erosions- und Sedimentationsraten und der Verdrängung natürlicher Lebensräume.
Ich wünsche Ihnen, dass Sie in diesem Heft spannende und anregende Geschichten entdecken. Denn es lohnt sich, einen Blick unter die Oberfläche zu werfen.
Prof. Manfred Strecker, PhD.
Professor für Allgemeine Geologie
Open Government
(2013)
Bis heute gelingt es kaum, Begriffe rund um die Verwaltungsreform – von New Public Management bis zu den E-Modellen – schlüssig voneinander abzugrenzen. Dieses Defizit wird bei der Betrachtung des Konzepts Open Government erneut sichtbar. Der Begriff Open Government ist dabei nicht nur aus verwaltungswissenschaftlicher, sondern mit Blick auf die Instrumente der direkten Demokratie auch aus politikwissenschaftlicher Perspektive zu betrachten. Handelt es sich um einen Sammelbegriff für hauptsächlich schon Dagewesenes?
Was Bürger bem(a)erken
(2013)
Eingebettet in die aktuelle Open-Government-Debatte gewinnen E-Bürgerdienste weiter an Bedeutung. Zu den Vorreitern internetbasierter Bürgerdienste wird der Brandenburger Bürgerservice Maerker gezählt, da dieser eine einfache Möglichkeit der Kommunikation zwischen Bürger und Verwaltung über Infrastrukturprobleme in der Gemeinde bietet. Auf der Grundlage von Experteninterviews und einer Umfrage unter den teilnehmenden Kommunen evaluieren die Autoren die Einführung und Umsetzung des Maerker Brandenburgs. Im Ergebnis zeigen sich neben einer großen Breite an Akzeptanz und Zustimmung unter den beteiligten Akteuren auch unausgeschöpfte Potenziale zur Verbesserung der Prozesse innerhalb der Verwaltung. Dieser Artikel stellt die Ergebnisse der Evaluation des Maerkers dar und gibt einen Ausblick auf weitere Entwicklungspotenziale.
Was Bürger bem(a)erken
(2013)
Eingebettet in die aktuelle Open-Government-Debatte gewinnen E-Bürgerdienste weiter an Bedeutung. Zu den Vorreitern internetbasierter Bürgerdienste wird der Brandenburger Bürgerservice Maerker gezählt, da dieser eine einfache Möglichkeit der Kommunikation zwischen Bürger und Verwaltung über Infrastrukturprobleme in der Gemeinde bietet. Auf der Grundlage von Experteninterviews und einer Umfrage unter den teilnehmenden Kommunen evaluieren die Autoren die Einführung und Umsetzung des Maerker Brandenburgs. Im Ergebnis zeigen sich neben einer großen Breite an Akzeptanz und Zustimmung unter den beteiligten Akteuren auch unausgeschöpfte Potenziale zur Verbesserung der Prozesse innerhalb der Verwaltung. Dieser Artikel stellt die Ergebnisse der Evaluation des Maerkers dar und gibt einen Ausblick auf weitere Entwicklungspotenziale.
Hochbegabung
(2013)
Das Thema „Hochbegabung“ erfährt seit mehreren Jahren zunehmende Aufmerksamkeit. Um intellektuell hochbegabte Kinder und Jugendliche angemessen fördern zu können, sind eine rechtzeitige Diagnostik und fundierte Beratung unumgänglich. Das vorliegende Buch bietet einen umfassenden und aktuellen Überblick über die theoretischen Grundlagen von Hochbegabung sowie über Möglichkeiten der Diagnostik und Förderung. Durch eine klare Strukturierung und didaktische Aufbereitung der Inhalte eignet es sich ideal für das (Selbst-)Studium und die berufliche Weiterbildung.
Einleitend setzt sich der Band mit den verschiedenen und sich zum Teil scheinbar widersprechenden Modellvorstellungen von Hochbegabung auseinander. Unterschiedliche Forschungszugänge zum Thema werden anhand prominenter Studien aufgezeigt. Weiterhin thematisiert der Band die Entwicklung von Hochbegabung sowie Eigenschaften von Hochbegabten. Hierzu gehören neben leistungsbezogenen Merkmalen bestimmte Temperamentseigenschaften oder soziale Kompetenzen. Erwartungswidrige Minderleistungen (Underachievement) und mögliche Entwicklungsbesonderheiten, die hoch relevante Themen in der pädagogisch-psychologischen Beratung Hochbegabter darstellen, werden ebenfalls berücksichtigt. Ausführlich erörtern die Autorinnen Möglichkeiten der Diagnostik von hochbegabten Kindern und Jugendlichen und stellen geeignete diagnostische Verfahren vor. Den Abschluss bildet ein Kapitel zu konkreten Fördermöglichkeiten in Kindergarten und Schule.
Klausurenkurs im Europarecht
(2013)
Der Euro spaltet Europa: Die überkommenen Begründungen der europäischen Integration ? Abbau zwischenstaatlicher Konflikte, Einbindung Deutschlands, Bewahrung von Recht und Demokratie sowie Mehrung von Sicherheit und Wohlstand ? verkehren sich in der Schuldenkrise in ihr Gegenteil. Das Buch stellt die Alternativlosigkeit der Rettungspolitik infrage und skizziert eine tragfähigere Ordnung für das Europa der Zukunft. Geppert thematisiert insbesondere die Verschärfung des Nationalismus, die Rückkehr der deutschen Frage, die Gefährdung der sozialen Marktwirtschaft, die Entmachtung der Parlamente, die Aushebelung des Rechts und die Lehren, die wir aus der Geschichte ziehen sollten.
Background: Recent studies have demonstrated a superior diagnostic accuracy of cardiovascular magnetic resonance (CMR) for the detection of coronary artery disease (CAD). We aimed to determine the comparative cost-effectiveness of CMR versus single-photon emission computed tomography (SPECT).
Methods: Based on Bayes' theorem, a mathematical model was developed to compare the cost-effectiveness and utility of CMR with SPECT in patients with suspected CAD. Invasive coronary angiography served as the standard of reference. Effectiveness was defined as the accurate detection of CAD, and utility as the number of quality-adjusted life-years (QALYs) gained. Model input parameters were derived from the literature, and the cost analysis was conducted from a German health care payer's perspective. Extensive sensitivity analyses were performed.
Results: Reimbursement fees represented only a minor fraction of the total costs incurred by a diagnostic strategy. Increases in the prevalence of CAD were generally associated with improved cost-effectiveness and decreased costs per utility unit (Delta QALY). By comparison, CMR was consistently more cost-effective than SPECT, and showed lower costs per QALY gained. Given a CAD prevalence of 0.50, CMR was associated with total costs of (sic)6,120 for one patient correctly diagnosed as having CAD and with (sic)2,246 per Delta QALY gained versus (sic)7,065 and (sic)2,931 for SPECT, respectively. Above a threshold value of CAD prevalence of 0.60, proceeding directly to invasive angiography was the most cost-effective approach.
Conclusions: In patients with low to intermediate CAD probabilities, CMR is more cost-effective than SPECT. Moreover, lower costs per utility unit indicate a superior clinical utility of CMR.
We study origin, parameter optimization, and thermodynamic efficiency of isothermal rocking ratchets based on fractional subdiffusion within a generalized non-Markovian Langevin equation approach. A corresponding multi-dimensional Markovian embedding dynamics is realized using a set of auxiliary Brownian particles elastically coupled to the central Brownian particle (see video on the journal web site). We show that anomalous subdiffusive transport emerges due to an interplay of nonlinear response and viscoelastic effects for fractional Brownian motion in periodic potentials with broken space-inversion symmetry and driven by a time-periodic field. The anomalous transport becomes optimal for a subthreshold driving when the driving period matches a characteristic time scale of interwell transitions. It can also be optimized by varying temperature, amplitude of periodic potential and driving strength. The useful work done against a load shows a parabolic dependence on the load strength. It grows sublinearly with time and the corresponding thermodynamic efficiency decays algebraically in time because the energy supplied by the driving field scales with time linearly. However, it compares well with the efficiency of normal diffusion rocking ratchets on an appreciably long time scale.
During an unusually massive filament eruption on 7 June 2011, SDO/AIA imaged for the first time significant EUV emission around a magnetic reconnection region in the solar corona. The reconnection occurred between magnetic fields of the laterally expanding CME and a neighbouring active region. A pre-existing quasi-separatrix layer was activated in the process. This scenario is supported by data-constrained numerical simulations of the eruption. Observations show that dense cool filament plasma was re-directed and heated in situ, producing coronal-temperature emission around the reconnection region. These results provide the first direct observational evidence, supported by MHD simulations and magnetic modelling, that a large-scale re-configuration of the coronal magnetic field takes place during solar eruptions via the process of magnetic reconnection.
Understanding the magnetic configuration of the source regions of coronal mass ejections (CMEs) is vital in order to determine the trigger and driver of these events. Observations of four CME productive active regions are presented here, which indicate that the pre-eruption magnetic configuration is that of a magnetic flux rope. The flux ropes are formed in the solar atmosphere by the process known as flux cancellation and are stable for several hours before the eruption. The observations also indicate that the magnetic structure that erupts is not the entire flux rope as initially formed, raising the question of whether the flux rope is able to undergo a partial eruption or whether it undergoes a transition in specific flux rope configuration shortly
before the CME.
In Germany, active bat rabies surveillance was conducted between 1993 and 2012. A total of 4546 oropharyngeal swab samples from 18 bat species were screened for the presence of EBLV-1- , EBLV-2- and BBLV-specific RNA. Overall, 0 center dot 15% of oropharyngeal swab samples tested EBLV-1 positive, with the majority originating from Eptesicus serotinus. Interestingly, out of seven RT-PCR-positive oropharyngeal swabs subjected to virus isolation, viable virus was isolated from a single serotine bat (E. serotinus). Additionally, about 1226 blood samples were tested serologically, and varying virus neutralizing antibody titres were found in at least eight different bat species. The detection of viral RNA and seroconversion in repeatedly sampled serotine bats indicates long-term circulation of the virus in a particular bat colony. The limitations of random-based active bat rabies surveillance over passive bat rabies surveillance and its possible application of targeted approaches for future research activities on bat lyssavirus dynamics and maintenance are discussed.
Communicating location-specific information to pedestrians is a challenging task which can be aided by user-friendly digital technologies. In this paper, landmark visibility analysis, as a means for developing more usable pedestrian navigation systems, is discussed. Using an algorithmic framework for image-based 3D analysis, this method integrates a 3D city model with identified landmarks and produces raster visibility layers for each one. This output enables an Android phone prototype application to indicate the visibility of landmarks from the user's actual position. Tested in the field, the method achieves sufficient accuracy for the context of use and improves navigation efficiency and effectiveness.
Proposing relevant perturbations to biological signaling networks is central to many problems in biology and medicine because it allows for enabling or disabling certain biological outcomes. In contrast to quantitative methods that permit fine-grained (kinetic) analysis, qualitative approaches allow for addressing large-scale networks. This is accomplished by more abstract representations such as logical networks. We elaborate upon such a qualitative approach aiming at the computation of minimal interventions in logical signaling networks relying on Kleene's three-valued logic and fixpoint semantics. We address this problem within answer set programming and show that it greatly outperforms previous work using dedicated algorithms.
This study presents results from a cross-modal priming experiment investigating inflected verb forms of German. A group of late learners of German with Russian as their native language (L1) was compared to a control group of German L1 speakers. The experiment showed different priming patterns for the two participant groups. The L1 German data yielded a stem-priming effect for inflected forms involving regular affixation and a partial priming effect for irregular forms irrespective of stem allomorphy. By contrast, the data from the late bilinguals showed reduced priming effects for both regular and irregular forms. We argue that late learners rely more on lexically stored inflected word forms during word recognition and less on morphological parsing than native speakers.
Previous research has shown that high phonotactic frequencies
facilitate the production of regularly inflected verbs in English-learning
children with specific language impairment (SLI) but not with typical
development (TD). We asked whether this finding can be replicated
for German, a language with a much more complex inflectional
verb paradigm than English. Using an elicitation task, the production
of inflected nonce verb forms (3 rd person singular with -t suffix)
with either high- or low-frequency subsyllables was tested in
sixteen German-learning children with SLI (ages 4;1–5 ;1), sixteen
TD-children matched for chronological age (CA) and fourteen TD-
children matched for verbal age (VA) (ages 3;0–3 ;11). The findings
revealed that children with SLI, but not CA- or VA-children, showed
differential performance between the two types of verbs, producing
more inflectional errors when the verb forms resulted in low-frequency
subsyllables than when they resulted in high-frequency subsyllables,
replicating the results from English-learning children.
The course timetabling problem can be generally defined as the task of assigning a number of lectures to a limited set of timeslots and rooms, subject to a given set of hard and soft constraints. The modeling language for course timetabling is required to be expressive enough to specify a wide variety of soft constraints and objective functions. Furthermore, the resulting encoding is required to be extensible for capturing new constraints and for switching them between hard and soft, and to be flexible enough to deal with different formulations. In this paper, we propose to make effective use of ASP as a modeling language for course timetabling. We show that our ASP-based approach can naturally satisfy the above requirements, through an ASP encoding of the curriculum-based course timetabling problem proposed in the third track of the second international timetabling competition (ITC-2007). Our encoding is compact and human-readable, since each constraint is individually expressed by either one or two rules. Each hard constraint is expressed by using integrity constraints and aggregates of ASP. Each soft constraint S is expressed by rules in which the head is the form of penalty (S, V, C), and a violation V and its penalty cost C are detected and calculated respectively in the body. We carried out experiments on four different benchmark sets with five different formulations. We succeeded either in improving the bounds or producing the same bounds for many combinations of problem instances and formulations, compared with the previous best known bounds.
In various biological systems and small scale technological applications particles transiently bind to a cylindrical surface. Upon unbinding the particles diffuse in the vicinal bulk before rebinding to the surface. Such bulk-mediated excursions give rise to an effective surface translation, for which we here derive and discuss the dynamic equations, including additional surface diffusion. We discuss the time evolution of the number of surface-bound particles, the effective surface mean squared displacement, and the surface propagator. In particular, we observe sub- and superdiffusive regimes. A plateau of the surface mean-squared displacement reflects a stalling of the surface diffusion at longer times. Finally, the corresponding first passage problem for the cylindrical geometry is analysed.
Fälle zum Zivilprozessrecht
(2013)
Die Vorstandsperspektive
(2013)
Business cases (BC) are often used to support information systems (IS) investment evaluation. Unfortunately, business case development (BCD) is a complex task, especially identifying and quantifying the benefits of a proposed investment. Although today’s business case frameworks (BCF) support BCD to some extent, they have several limitations
This article expands our current knowledge about ministerial selection in coalition governments and analyses why ministerial candidates succeed in acquiring a cabinet position after general elections. It argues that political parties bargain over potential office-holders during government-formation processes, selecting future cabinet ministers from an emerging bargaining pool'. The article draws upon a new dataset comprising all ministrable candidates discussed by political parties during eight government-formation processes in Germany between 1983 and 2009. The conditional logit regression analysis reveals that temporal dynamics, such as the day she enters the pool, have a significant effect on her success in achieving a cabinet position. Other determinants of ministerial selection discussed in the existing literature, such as party and parliamentary expertise, are less relevant for achieving ministerial office. The article concludes that scholarship on ministerial selection requires a stronger emphasis for its endogenous nature in government-formation as well as the relevance of temporal dynamics in such processes.
OCP-Place, a cross-linguistically well-attested constraint against pairs of consonants with shared [place], is psychologically real. Studies have shown that the processing of words violating OCP-Place is inhibited. Functionalists assume that OCP arises as a consequence of low-level perception: a consonant following another with the same [place] cannot be faithfully perceived as an independent unit. If functionalist theories were correct, then lexical access would be inhibited if two homorganic consonants conjoin at word boundaries-a problem that can only be solved with lexical feedback.
Here, we experimentally challenge the functional account by showing that OCP-Place can be used as a speech segmentation cue during pre-lexical processing without lexical feedback, and that the use relates to distributions in the input.
In Experiment 1, native listeners of Dutch located word boundaries between two labials when segmenting an artificial language. This indicates a use of OCP-Labial as a segmentation cue, implying a full perception of both labials. Experiment 2 shows that segmentation performance cannot solely be explained by well-formedness intuitions. Experiment 3 shows that knowledge of OCP-Place depends on language-specific input: in Dutch, co-occurrences of labials are under-represented, but co-occurrences of coronals are not. Accordingly, Dutch listeners fail to use OCP-Coronal for segmentation.
Despite recent growth of research on the effects of prosocial media, processes underlying these effects are not well understood. Two studies explored theoretically relevant mediators and moderators of the effects of prosocial media on helping. Study 1 examined associations among prosocial- and violent-media use, empathy, and helping in samples from seven countries. Prosocial-media use was positively associated with helping. This effect was mediated by empathy and was similar across cultures. Study 2 explored longitudinal relations among prosocial-video-game use, violent-video-game use, empathy, and helping in a large sample of Singaporean children and adolescents measured three times across 2 years. Path analyses showed significant longitudinal effects of prosocial- and violent-video-game use on prosocial behavior through empathy. Latent-growth-curve modeling for the 2-year period revealed that change in video-game use significantly affected change in helping, and that this relationship was mediated by change in empathy.
The aim of the present study was to examine how different types of tracking— between-school streaming, within-school streaming, and course-by-course tracking—shape students’ mathematics self-concept. This was done in an internationally comparative framework using data from the Programme for International Student Assessment (PISA). After controlling for individual and track mean achievement, results indicated that generally for students in course-by-course tracking, high-track students had higher mathematics self-concepts and low-track students had lower mathematics self-concepts. For students in between-school and within-school streaming, the reverse pattern was found. These findings suggest a solution to the ongoing debate about the effects of tracking on students’ academic self-concept and suggest that the reference groups to which students compare themselves differ according to the type of tracking.
The aim of the present study was to examine how different types of tracking—
between-school streaming, within-school streaming, and course-by-course
tracking—shape students’ mathematics self-concept. This was done in an
internationally comparative framework using data from the Programme for
International Student Assessment (PISA). After controlling for individual
and track mean achievement, results indicated that generally for students
in course-by-course tracking, high-track students had higher mathematics
self-concepts and low-track students had lower mathematics self-concepts.
For students in between-school and within-school streaming, the reverse pat-
tern was found. These findings suggest a solution to the ongoing debate about
the effects of tracking on students’ academic self-concept and suggest that the
reference groups to which students compare themselves differ according to the
type of tracking.
We report findings from psycholinguistic experiments investigating the detailed timing of processing morphologically complex words by proficient adult second (L2) language learners of English in comparison to adult native (L1) speakers of English. The first study employed the masked priming technique to investigate -ed forms with a group of advanced Arabic-speaking learners of English. The results replicate previously found L1/L2 differences in morphological priming, even though in the present experiment an extra temporal delay was offered after the presentation of the prime words.
The second study examined the timing of constraints against inflected forms inside derived words in English using the eye-movement monitoring technique and an additional acceptability judgment task with highly advanced Dutch L2 learners of English in comparison to adult L1 English controls. Whilst offline the L2 learners performed native-like, the eye-movement data showed that their online processing was not affected by the morphological constraint against regular plurals inside derived words in the same way as in native speakers. Taken together, these findings indicate that L2 learners are not just slower than native speakers in processing morphologically complex words, but that the L2 comprehension system employs real-time grammatical analysis (in this case, morphological information) less than the L1 system.
Background: Neuroenhancement (NE), the use of psychoactive substances in order to enhance a healthy individual's cognitive functioning from a proficient to an even higher level, is prevalent in student populations. According to the strength model of self-control, people fail to self-regulate and fall back on their dominant behavioral response when finite self-control resources are depleted. An experiment was conducted to test the hypothesis that ego-depletion will prevent students who are unfamiliar with NE from trying it.
Findings: 130 undergraduates, who denied having tried NE before (43% female, mean age = 22.76 +/- 4.15 years old), were randomly assigned to either an ego-depletion or a control condition. The dependent variable was taking an "energy-stick" (a legal nutritional supplement, containing low doses of caffeine, taurine and vitamin B), offered as a potential means of enhancing performance on the bogus concentration task that followed. Logistic regression analysis showed that ego-depleted participants were three times less likely to take the substance, OR = 0.37, p = .01.
Conclusion: This experiment found that trying NE for the first time was more likely if an individual's cognitive capacities were not depleted. This means that mental exhaustion is not predictive for NE in students for whom NE is not the dominant response. Trying NE for the first time is therefore more likely to occur as a thoughtful attempt at self-regulation than as an automatic behavioral response in stressful situations. We therefore recommend targeting interventions at this inter-individual difference. Students without previous reinforcing NE experience should be provided with information about the possible negative health outcomes of NE. Reconfiguring structural aspects in the academic environment (e.g. lessening workloads) might help to deter current users.
Background: Short lived, iteroparous animals in seasonal environments experience variable social and environmental conditions over their lifetime. Animals can be divided into those with a "young-of-the-year" life history (YY, reproducing and dying in the summer of birth) and an "overwinter" life history (OW, overwintering in a subadult state before reproducing next spring).
We investigated how behavioural patterns across the population were affected by season and sex, and whether variation in behaviour reflects the variation in life history patterns of each season. Applications of pace-of-life (POL) theory would suggest that long-lived OW animals are shyer in order to increase survival, and YY are bolder in order to increase reproduction. Therefore, we expected that in winter and spring samples, when only OW can be sampled, the animals should be shyer than in summer and autumn, when both OW and YY animals can be sampled. We studied common vole (Microtus arvalis) populations, which express typical, intra-annual density fluctuation. We captured a total of 492 voles at different months over 3 years and examined boldness and activity level with two standardised behavioural experiments.
Results: Behavioural variables of the two tests were correlated with each other. Boldness, measured as short latencies in both tests, was extremely high in spring compared to other seasons. Activity level was highest in spring and summer, and higher in males than in females.
Conclusion: Being bold in laboratory tests may translate into higher risk-taking in nature by being more mobile while seeking out partners or valuable territories. Possible explanations include asset-protection, with OW animals being rather old with low residual reproductive value in spring. Therefore, OW may take higher risks during this season. Offspring born in spring encounter a lower population density and may have higher reproductive value than offspring of later cohorts. A constant connection between life history and animal personality, as suggested by the POL theory, however, was not found. Nevertheless, correlations of traits suggest the existence of animal personalities. In conclusion, complex patterns of population dynamics, seasonal variation in life histories, and variability of behaviour due to asset-protection may cause complex seasonal behavioural dynamics in a population.
Background: Adaptive behavioural strategies promoting co-occurrence of competing species are known to result from a sympatric evolutionary past. Strategies should be different for indirect resource competition (exploitation, e.g., foraging and avoidance behaviour) than for direct interspecific interference (e.g., aggression, vigilance, and nest guarding). We studied the effects of resource competition and nest predation in sympatric small mammal species using semi-fossorial voles and shrews, which prey on vole offspring during their sensitive nestling phase. Experiments were conducted in caged outdoor enclosures. Focus common vole mothers (Microtus arvalis) were either caged with a greater white-toothed shrew (Crocidura russula) as a potential nest predator, with an herbivorous field vole (Microtus agrestis) as a heterospecific resource competitor, or with a conspecific resource competitor.
Results: We studied behavioural adaptations of vole mothers during pregnancy, parturition, and early lactation, specifically modifications of the burrow architecture and activity at burrow entrances. Further, we measured pre- and postpartum faecal corticosterone metabolites (FCMs) of mothers to test for elevated stress hormone levels. Only in the presence of the nest predator were prepartum FCMs elevated, but we found no loss of vole nestlings and no differences in nestling body weight in the presence of the nest predator or the heterospecific resource competitor. Although the presence of both the shrew and the field vole induced prepartum modifications to the burrow architecture, only nest predators caused an increase in vigilance time at burrow entrances during the sensitive nestling phase.
Conclusion: Voles displayed an adequate behavioural response for both resource competitors and nest predators. They modified burrow architecture to improve nest guarding and increased their vigilance at burrow entrances to enhance offspring survival chances. Our study revealed differential behavioural adaptations to resource competitors and nest predators.
Movement of organisms is one of the key mechanisms shaping biodiversity, e.g. the distribution of genes, individuals and species in space and time. Recent technological and conceptual advances have improved our ability to assess the causes and consequences of individual movement, and led to the emergence of the new field of ‘movement ecology’. Here, we outline how movement ecology can contribute to the broad field of biodiversity research, i.e. the study of processes and patterns of life among and across different scales, from genes to ecosystems, and we propose a conceptual framework linking these hitherto largely separated fields of research. Our framework builds on the concept of movement ecology for individuals, and demonstrates its importance for linking individual organismal movement with biodiversity. First, organismal movements can provide ‘mobile links’ between habitats or ecosystems, thereby connecting resources, genes, and processes among otherwise separate locations. Understanding these mobile links and their impact on biodiversity will be facilitated by movement ecology, because mobile links can be created by different modes of movement (i.e., foraging, dispersal, migration) that relate to different spatiotemporal scales and have differential effects on biodiversity. Second, organismal movements can also mediate coexistence in communities, through ‘equalizing’ and ‘stabilizing’ mechanisms. This novel integrated framework provides a conceptual starting point for a better understanding of biodiversity dynamics in light of individual movement and space-use behavior across spatiotemporal scales. By illustrating this framework with examples, we argue that the integration of movement ecology and biodiversity research will also enhance our ability to conserve diversity at the genetic, species, and ecosystem levels.
Background
Appearance-related social pressure plays an important role in the development of a negative body image and self-esteem as well as severe mental disorders during adolescence (e.g. eating disorders, depression). Identifying who is particularly affected by social pressure can improve targeted prevention and intervention, but findings have either been lacking or controversial. Thus the aim of this study is to provide a detailed picture of gender, weight, and age-related variations in the perception of appearance-related social pressure by peers and parents.
Methods
1112 German students between grades 7 and 9 (mean age: M = 13.38, SD = .81) filled in the Appearance-Related Social Pressure Questionnaire (German: FASD), which considers different sources (peers, parents) as well as various kinds of social pressure (e.g. teasing, modeling, encouragement).
Results
Girls were more affected by peer pressure, while gender differences in parental pressure seemed negligible. Main effects of grade-level suggested a particular increase in indirect peer pressure (e.g. appearance-related school and class norms) from early to middle adolescence. Boys and girls with higher BMI were particularly affected by peer teasing and exclusion as well as by parental encouragement to control weight and shape.
Conclusion
The results suggest that preventive efforts targeting body concerns and disordered eating should bring up the topic of appearance pressure in a school-based context and should strengthen those adolescents who are particularly at risk - in our study, girls and adolescents with higher weight status. Early adolescence and school transition appear to be crucial periods for these efforts. Moreover, the comprehensive assessment of appearance-related social pressure appears to be a fruitful way to further explore social risk-factors in the development of a negative body image.
Background: The use of psychoactive substances to neuroenhance cognitive performance is prevalent. Neuroenhancement (NE) in everyday life and doping in sport might rest on similar attitudinal representations, and both behaviors can be theoretically modeled by comparable means-to-end relations (substance-performance). A behavioral (not substance-based) definition of NE is proposed, with assumed functionality as its core component. It is empirically tested whether different NE variants (lifestyle drug, prescription drug, and illicit substance) can be regressed to school stressors.
Findings: Participants were 519 students (25.8 +/- 8.4 years old, 73.1% female). Logistic regressions indicate that a modified doping attitude scale can predict all three NE variants. Multiple NE substance abuse was frequent. Overwhelming demands in school were associated with lifestyle and prescription drug NE.
Conclusions: Researchers should be sensitive for probable structural similarities between enhancement in everyday life and sport and systematically explore where findings from one domain can be adapted for the other. Policy makers should be aware that students might misperceive NE as an acceptable means of coping with stress in school, and help to form societal sensitivity for the topic of NE among our younger ones in general.
Background
Natural accessions of Arabidopsis thaliana are a well-known system to measure levels of intraspecific genetic variation. Leaf starch content correlates negatively with biomass. Starch is synthesized by the coordinated action of many (iso)enzymes. Quantitatively dominant is the repetitive transfer of glucosyl residues to the non-reducing ends of α-glucans as mediated by starch synthases. In the genome of A. thaliana, there are five classes of starch synthases, designated as soluble starch synthases (SSI, SSII, SSIII, and SSIV) and granule-bound synthase (GBSS). Each class is represented by a single gene. The five genes are homologous in functional domains due to their common origin, but have evolved individual features as well. Here, we analyze the extent of genetic variation in these fundamental protein classes as well as possible functional implications on transcript and protein levels.
Findings
Intraspecific sequence variation of the five starch synthases was determined by sequencing the entire loci including promoter regions from 30 worldwide distributed accessions of A. thaliana. In all genes, a considerable number of nucleotide polymorphisms was observed, both in non-coding and coding regions, and several amino acid substitutions were identified in functional domains. Furthermore, promoters possess numerous polymorphisms in potentially regulatory cis-acting regions. By realtime experiments performed with selected accessions, we demonstrate that DNA sequence divergence correlates with significant differences in transcript levels.
Conclusions
Except for AtSSII, all starch synthase classes clustered into two or three groups of haplotypes, respectively. Significant difference in transcript levels among haplotype clusters in AtSSIV provides evidence for cis-regulation. By contrast, no such correlation was found for AtSSI, AtSSII, AtSSIII, and AtGBSS, suggesting trans-regulation. The expression data presented here point to a regulation by common trans-regulatory transcription factors which ensures a coordinated action of the products of these four genes during starch granule biosynthesis. The apparent cis-regulation of AtSSIV might be related to its role in the initiation of de novo biosynthesis of granules.
Introduction: We examined patterns of genetic divergence in 26 Mediterranean populations of the semi-terrestrial beachflea Orchestia montagui using mitochondrial (cytochrome oxidase subunit I), microsatellite (eight loci) and allozymic data. The species typically forms large populations within heaps of dead seagrass leaves stranded on beaches at the waterfront. We adopted a hierarchical geographic sampling to unravel population structure in a species living at the sea-land transition and, hence, likely subjected to dramatically contrasting forces.
Results: Mitochondrial DNA showed historical phylogeographic breaks among Adriatic, Ionian and the remaining basins (Tyrrhenian, Western and Eastern Mediterranean Sea) likely caused by the geological and climatic changes of the Pleistocene. Microsatellites (and to a lesser extent allozymes) detected a further subdivision between and within the Western Mediterranean and the Tyrrhenian Sea due to present-day processes. A pattern of isolation by distance was not detected in any of the analyzed data set.
Conclusions: We conclude that the population structure of O. montagui is the result of the interplay of two contrasting forces that act on the species population genetic structure. On one hand, the species semi-terrestrial life style would tend to determine the onset of local differences. On the other hand, these differences are partially counter-balanced by passive movements of migrants via rafting on heaps of dead seagrass leaves across sites by sea surface currents. Approximate Bayesian Computations support dispersal at sea as prevalent over terrestrial regionalism.
Biological age
(2013)
Leuchtkäfer & Orgelkoralle
(2013)
Leuchtende Käfer und Medusen, phosphoreszierende Meereswellen oder zu Stein erstarrende Korallen faszinierten den bisher vornehmlich als Dichter portraitierten Naturforscher Adelbert von Chamisso (1781–1838). Intensiver noch als den zoologischen und geologischen Phänomenen, widmete er sich der Scientia amabilis – der liebenswerten Wissenschaft von den Pflanzen. Der vielseitig Talentierte verfasste seine Reise um die Welt (1836), die bis heute als eine der stilistisch anspruchvollsten und lesenswertesten Reisebeschreibungen gilt. Diese Studie widmet sich dezidiert den naturkundlichen Studien Chamissos im Kontext der dreijährigen Rurik-Expedition sowie den zugehörigen Textproduktionen. Mit einem umfassenden Text- und Materialkorpus werden literatur- und kulturwissenschaftliche sowie wissenschaftshistorische Fragestellungen an das Werk gelegt und ertragreich beantwortet. Für die Reiseliteraturforschung wird bisher unbeachtetes Quellenmaterial ans Licht gebracht, gängige Thesen werden widerlegt, Quellen anderer Besatzungsmitglieder vergleichend betrachtet. Die Studie stellt den Naturforscher Chamisso in den Fokus, ohne den Dichter auszublenden, und widmet sich Fragen der Generierung, Vernetzung und Darstellung naturkundlichen Wissens in Texten, Illustrationen und Materialien zur Expedition – sie ist insgesamt für die Literatur- und Geschichtswissenschaft ebenso innovativ wie für die interdisziplinäre Geschichte des Wissens.
Dieser Band beschäftigt sich mit den theoretischen Grundlagen und der praktischen Umsetzung von Krafttraining mit Kindern und Jugendlichen. Ausgehend von der Kennzeichnung der körperlichen Situation und der Kraftentwicklung im Kindes- und Jugendalter werden die Effekte von Krafttraining bei Kindern und Jugendlichen aufgezeigt. Hierzu zählen neben Verbesserungen der Kraftausdauer, der Maximal- und Schnellkraft, die Förderung elementarer und sportartspezifischer Fertigkeiten sowie die günstige Beeinflussung gesundheitsrelevanter Faktoren (u.a. Verletzungshäufigkeit, Knochenstatus, kardio-vaskuläre und psycho-soziale Kennwerte).
Im Anschluss werden neuronale und muskuläre Mechanismen zur Erklärung der trainingsbedingten Anpassungen beschrieben. Das Kernstück des Buches bildet die Darstellung und Beschreibung vielfältiger Übungsbeispiele für ein Krafttraining an Maschinen, mit Freihanteln, Zusatzgeräten, dem eigenen Körpergewicht und ein Sprungkrafttraining. Hierbei wurden insbesondere Übungen ausgewählt, die sich für den Einsatz im Schul- und Vereinssport eignen. Dieses Buch dient somit Lehrern, Übungsleitern und Trainern, ein zielgerichtetes Krafttraining mit Kindern und Jugendlichen wirkungsvoll und sicher durchzuführen.
Global commons form a comparatively new part of international law, since the term appeared in international discussions and codifications only in the second half of the 20th century. The Common Heritage of Mankind is the corresponding legal principle that can establish an international regime to determine the legal status of non-sovereign territories and to allocate exploitation rights. Its main aim is to balance competing national claims by emphasising mankind’s common interest in the preservation and controlled exploitation of natural re-
sources. Against this background, the chapter sheds a critical light on attempts to transfer the institute of the Common Heritage of Mankind to the sphere of communication. Taking debates revolving around the New World Information and Communication Order in the framework of UNESCO since the late 1970s as a starting point, the author analyses the pitfalls and limits of attempts to establish governance structures for a global information order, including recent attempts to govern the internet.
Die Arbeit befasst sich mit der Schilderung von Paris im Erzählwerk von Delphine de Vigan, unter besonderer Berücksichtigung von zwei Romanen, No et moi (2007) und Les heures souterraines (2009), in denen der Großstadthintergrund einen zentralen Stellenwert erhält. Die Fragestellung richtet sich auf die Aspekte der Stadtdarstellung und auf die Rolle, die unterirdischen Durchgangsräumen dabei zugesprochen wird. Mögliche autoreflexive Deutungen der Stadt-Inszenierung in Bezug auf Sprache und Text, sowie Spuren einer mythisch-realistischen Charakterisierung der Stadt als Projektionsoberfläche des Imaginären
werden zum Schluss betrachtet.
Consciousness for fair consumption : conceptualization, scale development and empirical validation
(2013)
Sustainable consumption means that consumers act in an environmentally and socially responsible manner. Compared with the vast amount of studies concerning environmentally conscious consumer behaviour, relatively little is known about socially conscious consumption. The present paper focuses on fair consumption as an important aspect of social consumption. In our study, consciousness for fair consumption (CFC) is defined as a latent disposition of consumers to prefer products that are produced and traded in compliance with fair labour and business practices. A scale to measure CFC was conceptualized and tested in three independent empirical studies. Two studies were conducted at European universities (2010 and 2012) and used 352 and 362 undergraduate business students respectively. The third study, conducted in 2011, used 141 employees at a European university. The results confirmed the reliability and validity of the new CFC scale across samples. While being moderately related to other aspects of sustainable consumption such as ecological concern and moral reasoning, CFC was significantly distinct from those concepts. Most importantly, it was established that the CFC, as measured by the new CFC scale, is a strong determinant of consumption of fair trade products that has been neglected in existing research.
The “triple bottom line” concept (planet, people, and profit) represents an important guideline for the sustainable, hence future-oriented, development of societies and for the behaviors of all societal members. For institutions promoting societal change, as well as for companies being confronted with growing expectations regarding compelling contributions to sustainable changes, it is of great importance to know if, and to what extent, consumers have already internalized the idea of sustainability. Against the background of existing research gaps regarding a comprehensive measurement of the consciousness for sustainable consumption (CSC), the authors present the result of a scale development. Consciousness was operationalized by weighting personal beliefs with the importance attached by consumers to sustainability dimensions. Four separate tests of the CSC scale indicated an appropriate psychometric quality of the scale and provided support for this new measurement approach that incorporates the environmental, social and economic dimensions of sustainability.
Der Staat im Recht – getragen vom und gebunden durch das Recht, orientiert an Gemeinwohl und Individualrechten gleichermaßen – ist Gegenstand und Ziel des wissenschaftlichen Wirkens von Eckart Klein.
Eckart Klein, dessen 70. Geburtstag Anlass zu dieser Festschrift ist, hat sich als Rechtswissenschaftler dem Öffentlichen Recht in seiner ganzen Bandbreite gewidmet, wobei die Tätigkeit am Heidelberger Max-Planck-Institut für ausländisches öffentliches Recht und Völkerrecht und die Zeit als wissenschaftlicher Mitarbeiter am Bundesverfassungsgericht seine Interessen nachhaltig geprägt und fokussiert haben. Wichtige Themen seiner Publikationstätigkeit während seiner gesamten wissenschaftlichen Laufbahn sind dementsprechend das Verfassungsprozessrecht, das allgemeine Völkerrecht, das Recht der internationalen Organisationen und der internationale Menschenrechtsschutz.
Nach einer Station an der Johannes Gutenberg-Universität in Mainz wechselte er an die Universität Potsdam. Hier gründete er auch das MenschenRechtsZentrum der Universität Potsdam, dem er als Direktor vorstand. Der Jurist ergänzte seine Tätigkeit als Hochschullehrer durch die Wahrnehmung von Richterämtern an den Oberverwaltungsgerichten in Koblenz und Frankfurt (Oder) sowie am Staatsgerichtshof in Bremen. Außerdem war er Mitglied des Menschenrechtsausschusses der Vereinten Nationen und wirkte mehrfach als deutscher Ad-hoc-Richter an Verfahren vor dem Europäischen Gerichtshof für Menschenrechte mit. Dass bei alldem die akademische Lehre nicht zu kurz kam, war für Eckart Klein oberstes Gebot.
Schüler und Weggefährten haben in dieser Festschrift Beiträge aus den Bereichen des Völkerrechts, des Europarechts und des nationalen Rechts versammelt, um die Position des Staates im Recht aus unterschiedlichen Blickwinkeln auszuloten, Grenzen staatlichen Handelns zu markieren und nach Maßstäben für hoheitliche Entscheidungen zu fragen.
Les représentants du relativisme linguistique du XXème siècle qui se réclament de l’histoire de leur théorie mentionnent normalement Guillaume de Humboldt comme initiateur de l’idée que la manière particulière de penser d’un peuple dépendrait de sa langue. La théorie de Humboldt s’avère, cependant, difficilement maniable dans la recherche linguistique. Malgré une similitude évidente dans certaines positions, comme par exemple les concepts d’‘articulation’ et de ‘valeur’, le renouvellement de la linguistique sur une base saussurienne, au début du XXème siècle, se passait des idées de Humboldt. Il n’y avait que quelques philologues ‘idéalistes’ qui poursuivaient ce type de recherche. Ainsi, Karl Vossler constatait un parallélisme entre la langue et la culture et les considérait comme résultats de la création humaine. Le mécontentement quant à la description des langues selon le paradigme positiviste des néogrammairiens s’articulait nettement.
Le concept d’une vision linguistique du monde fut développé dans la théorie des néohumboldtiens (Weisgerber, Trier et autres) qui affirmaient que l’individu s’approprie le monde à travers la langue. Des différences entre des langues influeraient considérablement sur les facultés cognitives des hommes et sur leur comportement. L’idée humboldtienne de l’energeia se trouvait exclue de ces théories qui aspiraient à un renouvellement de la langue maternelle dans le sens d’une ‘grammaire à partir du contenu’ (inhaltbezogene Grammatik). Ce type de réflexion linguistique se prêtait aussi à une utilisation politique sous le national-socialisme. La théorie de Weisgerber, déclarée comme antiraciste et anti-national-socialiste par l’auteur lui-même, fut considérée comme « mother-tongue fascism » par Christopher Hutton. La relation entre le relativisme linguistique et la doctrine nationale-socialiste est évidente dans les écrits de plusieurs auteurs, par exemple dans « notre langue maternelle comme arme et instrument de la pensée allemande » de Georg Schmidt-Rohr. Il y eut des implications racistes de la théorie de quelques indo-germanistes bien avant 1933.
L’influence des néohumboldtiens s’est poursuivie jusqu’aux années 60, époque où ils durent faire place à des linguistes structuralistes et générativistes. On trouve dans quelques vérifications plus récentes du relativisme linguistique des références à des textes antérieurs à Humboldt. Par exemple, Gumperz et Levison (1996) citent le concours de l’Académie de Berlin sur la question suivante : Quelle est l'influence réciproque des opinions du peuple sur le langage et du langage sur les opinions? Est-ce que cet élargissement de l’horizon de rétrospection a quelque chose à voir avec la conscience d’une portée sociale possible de cette théorie ?
This article investigates whether self-employed households use consumer loans - in particular, instalment loans and overdrafts - to finance business activities. Controlling for financial and nonfinancial household variables, we show that self-employed households particularly use personal overdrafts significantly more often than employee households. When analysing the correlation between consumer loan take-ups and consumption of self-employed in comparison to employee households, we find first evidence that overdrafts are used by self-employed to finance their business as well. This indicates that intermingling constitutes a financing strategy when regular business loans might not be accessible.
Small and medium-sized enterprises (SME) contribute to innovation and economic growth, despite their resource shortages and lack of professional intellectual property (IP) management practices. Drawing on social practice theory and combining insights from recent scholarship on IP strategies and its management, this paper examines the cases of three pharmaceutical SME providing insights into how they appropriate returns on research and development (R&D) investments. It discusses their IP strategies and management practices, examining how the IP management practices are embedded in the firm's organisational structure. Moreover, this paper develops recommendations for SME regarding the professionalisation of their IP management practices.
Bacteriophage HK620 recognizes and cleaves the O-antigen polysaccharide of Escherichia coli serogroup O18A1 with its tailspike protein (TSP). HK620TSP binds hexasaccharide fragments with low affinity, but single amino acid exchanges generated a set of high-affinity mutants with submicromolar dissociation constants. Isothermal titration calorimetry showed that only small amounts of heat were released upon complex formation via a large number of direct and solvent-mediated hydrogen bonds between carbohydrate and protein. At room temperature, association was both enthalpy- and entropy-driven emphasizing major solvent rearrangements upon complex formation. Crystal structure analysis showed identical protein and sugar conformers in the TSP complexes regardless of their hexasaccharide affinity. Only in one case, a TSP mutant bound a different hexasaccharide conformer. The extended sugar binding site could be dissected in two regions: first, a hydrophobic pocket at the reducing end with minor affinity contributions. Access to this site could be blocked by a single aspartate to asparagine exchange without major loss in hexasaccharide affinity. Second, a region where the specific exchange of glutamate for glutamine created a site for an additional water molecule. Side-chain rearrangements upon sugar binding led to desolvation and additional hydrogen bonding which define this region of the binding site as the high-affinity scaffold.
This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.
Solid surfaces are modified using photo-crosslinkable copolymers based on oligo(ethylene glycol) methacrylate (OEGMA) bearing 2-(4-benzoylphenoxy) ethyl methacrylate (BPEM) as a photosensitive crosslinking unit. Thin films of about 100 nm are formed by spin-coating these a priori highly biocompatible copolymers onto silicon substrates. Subsequent UV-irradiation assures immobilization and crosslinking of the hydrogel films. Their stability is controlled by the number of crosslinker units per chain and the molar mass of the copolymers. The swelling of the hydrogel layers, as investigated by ellipsometry, can be tuned by the crosslinker content in the copolymer. If films are built from the ternary copolymers of OEGMA, BPEM and 2-(2-methoxyethoxy) ethyl methacrylate (MEO(2)MA), the hydrogel films exhibit a swelling/deswelling transition of the lower critical solution temperature (LCST) type. The observed thermally induced hydrogel collapse is fully reversible and the onset temperature of the transition can be tuned at will by the copolymer composition. Different from analogously prepared thermo-responsive hydrogel films of photocrosslinked poly(N-isopropylacrylamide), the swelling-deswelling transition occurs more gradually, but shows no hysteresis.
Various techniques are utilized by the seismological community, extractive industries, energy and geoengineering companies to identify earthquake nucleation processes in close proximity to engineering operation points. These operations may comprise fluid extraction or injections, artificial water reservoir impoundments, open pit and deep mining, deep geothermal power generations or carbon sequestration. In this letter to the editor, we outline several lines of investigation that we suggest to follow to address the discrimination problem between natural seismicity and seismic events induced or triggered by geoengineering activities. These suggestions have been developed by a group of experts during several meetings and workshops, and we feel that their publication as a summary report is helpful for the geoscientific community. Specific investigation procedures and discrimination approaches, on which our recommendations are based, are also published in this Special Issue (SI) of Journal of Seismology.
Preface to the special issue "Triggered and induced seismicity: probabilities and discrimination"
(2013)
Cyanobacteria produce an unparalleled variety of toxins that can cause severe health problems or even death in humans, and wild or domestic animals. In the last decade, biosynthetic pathways have been assigned to the majority of the known toxin families. This review summarizes current knowledge about the enzymatic basis for the production of the hepatotoxins microcystin and nodularin, the cytotoxin cylindrospermopsin, the neurotoxins anatoxin and saxitoxin, and the dermatotoxin lyngbyatoxin. Elucidation of the biosynthetic pathways of the toxins has paved the way for the development of molecular techniques for the detection and quantification of the producing cyanobacteria in different environments. Phylogenetic analyses of related clusters from a large number of strains has also allowed for the reconstruction of the evolutionary scenarios that have led to the emergence, diversification, and loss of such gene clusters in different strains and genera of cyanobacteria. Advances in the understanding of toxin biosynthesis and evolution have provided new methods for drinking-water quality control and may inspire the development of techniques for the management of bloom formation in the future.
This study focuses on the evolutionary relationships among Turkish species of the cave cricket genus Troglophilus. Fifteen populations were studied for sequence variation in a fragment (543 base pairs) of the mitochondrial DNA (mtDNA) 16S rDNA gene (16S) to reconstruct their phylogenetic relationships and biogeographic history. Genetic data retrieved three main clades and at least three divergent lineages that could not be attributed to any of the taxa known for the area. Molecular time estimates suggest that the diversification of the group took place between the Messinian and the Plio-Pleistocene.
In aqueous solution, symmetric triblock copolymers with a thermoresponsive middle block and hydrophobic end blocks form flower-like core-shell micelles which collapse and aggregate upon heating through the cloud point (CP). The collapse of the micellar shell and the intermicellar aggregation are followed in situ and in real-time using time-resolved small-angle neutron scattering (SANS), while heating micellar solutions of a poly((styrene-d(8))-b-(N-isopropyl acrylamide)-b-(styrene-d(8))) triblock copolymer in D2O rapidly through their CP. The influence of polymer concentration as well as of the start and target temperatures is addressed. In all cases, the micellar collapse is very fast. The collapsed micelles immediately form small clusters which contain voids. They densify which slows down or even stops their growth. For low concentrations and target temperatures just above the CP, i.e. shallow temperature jumps, the subsequent growth of the clusters is described by diffusion-limited aggregation. In contrast, for higher concentrations and/or higher target temperatures, i.e. deep temperature jumps, intermicellar bridges dominate the growth. Eventually, in all cases, the clusters coagulate which results in macroscopic phase separation. For shallow temperature jumps, the cluster surfaces stay rough; whereas for deep temperature jumps, a concentration gradient develops at late stages. These results are important for the development of conditions for thermal switching in applications, e.g. for the use of thermoresponsive micellar systems for transport and delivery purposes.
A population of Luisia curtisii (Orchidaceae: Aeridinae) in northern Thailand was studied with regard to pollination biology. Although a high level of self-compatibility was demonstrated experimentally, the very low natural fruit set (1.4-1.9 %) clearly indicated that the species depends on external agents for pollination. Our observations suggest that L. curtisii is pollinated by beetles, as Lema unicolor (Chrysomelidae) and Clinteria ducalis (Scarabaeidae) were the only flower visitors observed to carry pollinaria of this species. The hypothesis of specialised cantharophily is further supported by 2-methylbutyric acid and caproic acid being striking components of the floral scent. Judging from the lack of nectar and the behaviour of visiting beetles, the pollination system seems to rely on food or brood site deception. Retention of the anther on the pollinarium for some time after pollinarium removal probably reduces the frequency of insect-mediated autogamy and geitonogamy in Luisia curtisii-a possibility that was supported by comparative data on (1) the anther retention time and inflorescence visitation time of Lema unicolor and (2) stigma and anther length in the orchid. Existing reports of specialised beetle pollination in orchids are reviewed, and we conclude that there is accumulating evidence that specialised cantharophily is more common in the Orchidaceae than previously assumed.
Birth weight within the normal range is associated with a variety of adult-onset diseases, but the mechanisms behind these associations are poorly understood(1). Previous genome-wide association studies of birth weight identified a variant in the ADCY5 gene associated both with birth weight and type 2 diabetes and a second variant, near CCNL1, with no obvious link to adult traits(2). In an expanded genome-wide association metaanalysis and follow-up study of birth weight (of up to 69,308 individuals of European descent from 43 studies), we have now extended the number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking. Five of the loci are known to be associated with other phenotypes: ADCY5 and CDKAL1 with type 2 diabetes, ADRB1 with adult blood pressure and HMGA2 and LCORL with adult height. Our findings highlight genetic links between fetal growth and postnatal growth and metabolism.