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In 1735, the Leipzig professor of medicine Samuel Theodor Quellmaltz (1696–1758) designed and built an artificial horse. He presented it in an illustrated construction manual, which included precise information about the materials and dimensions of this wooden horse for therapeutic use. This contribution analyses Quellmaltz’s invention of the ‘machine horse’ as a medical and technological contribution to prevalent theories about the paradigmatic role of the machine in Enlightenment thought.