Juliane Schatz, Bernd Ohlendorf, Peter Busse, Gerrit Pelz, Dietrich Dolch, Jens Teubner, Jorge A. Encarnacao, Ralf-Udo Mühle, M. Fischer, Bernd Hoffmann, Linda Kwasnitschka, Anne Balkema-Buschmann, Thomas Christoph Mettenleiter, T. Müller, Conrad M. Freuling
- In Germany, active bat rabies surveillance was conducted between 1993 and 2012. A total of 4546 oropharyngeal swab samples from 18 bat species were screened for the presence of EBLV-1- , EBLV-2- and BBLV-specific RNA. Overall, 0 center dot 15% of oropharyngeal swab samples tested EBLV-1 positive, with the majority originating from Eptesicus serotinus. Interestingly, out of seven RT-PCR-positive oropharyngeal swabs subjected to virus isolation, viable virus was isolated from a single serotine bat (E. serotinus). Additionally, about 1226 blood samples were tested serologically, and varying virus neutralizing antibody titres were found in at least eight different bat species. The detection of viral RNA and seroconversion in repeatedly sampled serotine bats indicates long-term circulation of the virus in a particular bat colony. The limitations of random-based active bat rabies surveillance over passive bat rabies surveillance and its possible application of targeted approaches for future research activities on bat lyssavirus dynamics andIn Germany, active bat rabies surveillance was conducted between 1993 and 2012. A total of 4546 oropharyngeal swab samples from 18 bat species were screened for the presence of EBLV-1- , EBLV-2- and BBLV-specific RNA. Overall, 0 center dot 15% of oropharyngeal swab samples tested EBLV-1 positive, with the majority originating from Eptesicus serotinus. Interestingly, out of seven RT-PCR-positive oropharyngeal swabs subjected to virus isolation, viable virus was isolated from a single serotine bat (E. serotinus). Additionally, about 1226 blood samples were tested serologically, and varying virus neutralizing antibody titres were found in at least eight different bat species. The detection of viral RNA and seroconversion in repeatedly sampled serotine bats indicates long-term circulation of the virus in a particular bat colony. The limitations of random-based active bat rabies surveillance over passive bat rabies surveillance and its possible application of targeted approaches for future research activities on bat lyssavirus dynamics and maintenance are discussed.…
MetadatenVerfasserangaben: | Juliane Schatz, Bernd Ohlendorf, Peter Busse, Gerrit Pelz, Dietrich Dolch, Jens Teubner, Jorge A. EncarnacaoORCiD, Ralf-Udo Mühle, M. Fischer, Bernd Hoffmann, Linda Kwasnitschka, Anne Balkema-Buschmann, Thomas Christoph Mettenleiter, T. Müller, Conrad M. Freuling |
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URN: | urn:nbn:de:kobv:517-opus4-415140 |
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DOI: | https://doi.org/10.25932/publishup-41514 |
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ISSN: | 1866-8364 |
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Titel des übergeordneten Werks (Englisch): | Postprints der Universität Potsdam Humanwissenschaftliche Reihe |
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Untertitel (Englisch): | a detailed analysis and future perspectives |
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Schriftenreihe (Bandnummer): | Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe (533) |
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Publikationstyp: | Postprint |
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Sprache: | Englisch |
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Datum der Erstveröffentlichung: | 14.02.2019 |
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Erscheinungsjahr: | 2013 |
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Veröffentlichende Institution: | Universität Potsdam |
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Datum der Freischaltung: | 14.02.2019 |
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Freies Schlagwort / Tag: | Bat rabies; epidemiology; lyssavirus; surveillance |
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Ausgabe: | 533 |
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Seitenanzahl: | 12 |
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Quelle: | Epidemiology and Infection 142 (2014) 6, S. 1155–1166 DOI: 10.1017/S0950268813002185 |
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Organisationseinheiten: | Humanwissenschaftliche Fakultät |
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DDC-Klassifikation: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Peer Review: | Referiert |
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Publikationsweg: | Open Access |
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Fördermittelquelle: | Cambridge University Press (CUP) |
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Lizenz (Deutsch): | Keine öffentliche Lizenz: Unter Urheberrechtsschutz |
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Externe Anmerkung: | Bibliographieeintrag der Originalveröffentlichung/Quelle |
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