Aminergic signal transduction in invertebrates : focus on tyramine and octopamine receptors
- Electro-chemical signal transduction is the basis of communication between n eurons and their target cells. An important group of neuroactive substances that are released by action potentials from neurons are the biogenic amines. These a re small organic molecules that bind to specific receptors located in the target cell membrane. Once activated these receptors cause changes in the intracellula r concentration of second messengers, i.e. cyclic nucleotides, phosphoinositides , or Ca2+, leading to slow but long-lasting cellular responses. Biochemical, pha rmacological, physiological, and molecular biological approaches have unequivoca lly shown that biogenic amines are important regulators of cellular function in both vertebrates and invertebrates. In this review, we will concentrate on the p roperties of two biogenic amines and their receptors that were originally identi fied in invertebrates: tyramine and octopamine.
Author details: | Wolfgang BlenauORCiDGND, Arnd Baumann |
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URN: | urn:nbn:de:kobv:517-opus-44271 |
Publication series (Volume number): | Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (paper 107) |
Publication type: | Postprint |
Language: | English |
Publication year: | 2003 |
Publishing institution: | Universität Potsdam |
Release date: | 2010/07/01 |
Source: | Recent research developments in neurochemistry 6 (2003), S. 225 - 240 |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
DDC classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
License (German): | Keine öffentliche Lizenz: Unter Urheberrechtsschutz |
External remark: | The article was originally published by Research Signpost: Recent research developments in neurochemistry. - 6 (2003), pp. 225 - 240 ISBN 81-271-0021-8 |