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Dendritic polyglycerol-poly(ethylene glycol)-based polymer networks for biosensing application

  • This work describes the formation of a new dendritic polyglycerol-poly(ethylene glycol)-based 3D polymer network as a matrix for immobilization of the redox enzyme periplasmatic aldehyde oxidoreductase to create an electrochemical biosensor. The novel network is built directly on the gold surface, where it simultaneously stabilizes the enzyme for up to 4 days. The prepared biosensors can be used for amperometric detection of benzaldehyde in the range of 0.8-400 mu M.

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Author:Pradip Dey, Miriam Adamovski, Simon Friebe, Artavazd BadalyanORCiDGND, Radu-Cristian Mutihac, Florian Paulus, Silke Leimkuehler, Ursula WollenbergerORCiDGND, Rainer Haag
DOI:https://doi.org/10.1021/am502018x
ISSN:1944-8244
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=24882361
Parent Title (English):ACS applied materials & interfaces
Publisher:American Chemical Society
Place of publication:Washington
Document Type:Article
Language:English
Year of first Publication:2014
Year of Completion:2014
Release Date:2017/03/27
Tag:amperometry; biosensors; dendritic; hydrogel
Volume:6
Issue:12
Page Number:5
First Page:8937
Last Page:8941
Funder:Cluster of Excellence "UniCAT" (Unifying Concepts in Catalysis, Berlin); graduate school "BIG NSE"; LB Brandenburg (Terasens)
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie
Peer Review:Referiert