Mobile diagnostics and consultation for the prevention of the metabolic syndrome and its secondary diseases in Brandenburg—study protocol of a regional prospective cohort study
- Background The metabolic syndrome (MetS) is a risk cluster for a number of secondary diseases. The implementation of prevention programs requires early detection of individuals at risk. However, access to health care providers is limited in structurally weak regions. Brandenburg, a rural federal state in Germany, has an especially high MetS prevalence and disease burden. This study aims to validate and test the feasibility of a setup for mobile diagnostics of MetS and its secondary diseases, to evaluate the MetS prevalence and its association with moderating factors in Brandenburg and to identify new ways of early prevention, while establishing a “Mobile Brandenburg Cohort” to reveal new causes and risk factors for MetS. Methods In a pilot study, setups for mobile diagnostics of MetS and secondary diseases will be developed and validated. A van will be equipped as an examination room using point-of-care blood analyzers and by mobilizing standard methods. In study part A, these mobile diagnostic units will be placed at differentBackground The metabolic syndrome (MetS) is a risk cluster for a number of secondary diseases. The implementation of prevention programs requires early detection of individuals at risk. However, access to health care providers is limited in structurally weak regions. Brandenburg, a rural federal state in Germany, has an especially high MetS prevalence and disease burden. This study aims to validate and test the feasibility of a setup for mobile diagnostics of MetS and its secondary diseases, to evaluate the MetS prevalence and its association with moderating factors in Brandenburg and to identify new ways of early prevention, while establishing a “Mobile Brandenburg Cohort” to reveal new causes and risk factors for MetS. Methods In a pilot study, setups for mobile diagnostics of MetS and secondary diseases will be developed and validated. A van will be equipped as an examination room using point-of-care blood analyzers and by mobilizing standard methods. In study part A, these mobile diagnostic units will be placed at different locations in Brandenburg to locally recruit 5000 participants aged 40-70 years. They will be examined for MetS and advice on nutrition and physical activity will be provided. Questionnaires will be used to evaluate sociodemographics, stress perception, and physical activity. In study part B, participants with MetS, but without known secondary diseases, will receive a detailed mobile medical examination, including MetS diagnostics, medical history, clinical examinations, and instrumental diagnostics for internal, cardiovascular, musculoskeletal, and cognitive disorders. Participants will receive advice on nutrition and an exercise program will be demonstrated on site. People unable to participate in these mobile examinations will be interviewed by telephone. If necessary, participants will be referred to general practitioners for further diagnosis. Discussion The mobile diagnostics approach enables early detection of individuals at risk, and their targeted referral to local health care providers. Evaluation of the MetS prevalence, its relation to risk-increasing factors, and the “Mobile Brandenburg Cohort” create a unique database for further longitudinal studies on the implementation of home-based prevention programs to reduce mortality, especially in rural regions. Trial registration German Clinical Trials Register, DRKS00022764; registered 07 October 2020—retrospectively registered.…
Author details: | Anne SchraplauORCiDGND, Andrea BlockORCiDGND, Andreas HäuslerORCiDGND, Pia-Maria WippertORCiDGND, Michael A. RappORCiDGND, Heinz VöllerORCiDGND, Klaus BonaventuraORCiDGND, Frank MayerORCiDGND |
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DOI: | https://doi.org/10.1186/s40814-021-00898-w |
ISSN: | 2055-5784 |
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/34462012 |
Title of parent work (English): | Pilot and Feasibility Studies |
Subtitle (English): | the Mobile Brandenburg Cohort |
Publisher: | BioMed Central (Springer Nature) |
Place of publishing: | London |
Publication type: | Article |
Language: | English |
Date of first publication: | 2021/08/30 |
Publication year: | 2021 |
Release date: | 2022/05/10 |
Tag: | Metabolic syndrome; Mobile diagnostics; Nutrition; Physical activity; Prevention; Rural health |
Volume: | 7 |
Article number: | 166 |
Number of pages: | 11 |
First page: | 1 |
Last Page: | 11 |
Funding institution: | Ministry of Science, Research and Culture (MWFK) of the Federal State of Brandenburg (Germany) |
Funding institution: | Projekt DEAL |
Funding institution: | European Union (European Regional Development Fund, ERDF) within the program "Starkung der technologischen und anwendungsnahen Forschung an Wissenschaftseinrichtungen (StaF-RL)" |
Funding number: | 85000956 |
Organizational units: | Extern / Extern |
Humanwissenschaftliche Fakultät / Strukturbereich Kognitionswissenschaften / Department Sport- und Gesundheitswissenschaften | |
DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Peer review: | Referiert |
Grantor: | Publikationsfonds der Universität Potsdam |
Publishing method: | Open Access / Gold Open-Access |
License (German): | CC-BY - Namensnennung 4.0 International |
External remark: | Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Humanwissenschaftliche Reihe ; 759 |