Thirty years of haemoglobin electrochemistry
- Electrochemical investigations of the blood oxygen carrier protein include both mediated and direct electron transfer. The reaction of haemoglobin (Hb) with typical mediators, e.g., ferricyanide, can be quantified by measuring the produced ferrocyanide which is equivalent to the Hb concentration. Immobilization of the mediator within the electrode body allows reagentless electrochemical measuring of Hb. On the other hand, entrapment of the protein within layers of polyclectrolytes, lipids, nanoparticles of clay or gold leads to a fast heterogeneous electron exchange of the partially denatured Hb. (c) 2005 Elsevier B.V. All rights reserved
Author details: | Frieder W. SchellerORCiDGND, Nikitas Bistolas, Songqin Liu, Michael Jänchen, Martin Katterle, Ursula WollenbergerORCiDGND |
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Publication type: | Article |
Language: | English |
Year of first publication: | 2005 |
Publication year: | 2005 |
Release date: | 2017/03/24 |
Source: | Advances in Colloid and Interface Science. - 116 (2005), 1-3, S. 111 - 120 |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
Peer review: | Referiert |