Synthesis of polysarcosine from air and moisture stable N-phenoxycarbonyl-N-methylglycine assisted by tertiary amine base
- Polysarcosine (Mn = 3650–20 000 g mol−1, Đ ∼ 1.1) was synthesized from the air and moisture stable N-phenoxycarbonyl-N-methylglycine. Polymerization was achieved by in situ transformation of the urethane precursor into the corresponding N-methylglycine-N-carboxyanhydride, when in the presence of a non-nucleophilic tertiary amine base and a primary amine initiator.
Author details: | Afroditi Doriti, Sarah M. Brosnan, Steffen M. Weidner, Helmut SchlaadORCiDGND |
---|---|
URN: | urn:nbn:de:kobv:517-opus4-95852 |
Publication series (Volume number): | Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (255) |
Publication type: | Postprint |
Language: | English |
Date of first publication: | 2016/04/08 |
Publication year: | 2016 |
Publishing institution: | Universität Potsdam |
Release date: | 2016/09/15 |
Tag: | acids; activated urethane derivatives; carboxyanhydrides; copolymers; phosgene-free synthesis; polypeptides; ring-opening polymerization |
First page: | 3067 |
Last Page: | 3070 |
Source: | Polym. Chem. (2016), Nr. 8, S. 3067-3070. DOI: 10.1039/C6PY00221H |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Peer review: | Referiert |
Publishing method: | Open Access |
License (German): | Keine öffentliche Lizenz: Unter Urheberrechtsschutz |
External remark: | Bibliographieeintrag der Originalveröffentlichung/Quelle |