Enzyme cascade reactions: synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem
- A one-pot tandem enzyme reaction using galactose oxidase M3-5 and aldehyde oxidase PaoABC was used to convert hydroxymethylfurfural (HMF) to the pure bioplastics precursor FDCA in 74% isolated yield. A range of alcohols was also converted to carboxylic acids in high yield under mild conditions.
Author details: | Shane M. McKenna, Silke LeimkühlerORCiDGND, Susanne Herter, Nicholas J. Turner, Andrew J. Carnell |
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DOI: | https://doi.org/10.1039/c5gc00707k |
ISSN: | 1463-9262 |
ISSN: | 1463-9270 |
Title of parent work (English): | Green chemistry : an international journal and green chemistry resource |
Publisher: | Royal Society of Chemistry |
Place of publishing: | Cambridge |
Publication type: | Article |
Language: | English |
Year of first publication: | 2015 |
Publication year: | 2015 |
Release date: | 2017/03/27 |
Volume: | 17 |
Issue: | 6 |
Number of pages: | 5 |
First page: | 3271 |
Last Page: | 3275 |
Funding institution: | Engineering and Physical Sciences Research Council (EPSRC); Innovative Medicines Initiative [115360]; Royal Society Wolfson Merit Award |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
Peer review: | Referiert |