Surface regeneration of microfluidic microarray printheads through plasma techniques
- This work describes a method for surface regeneration of microfluidic microarray printheads through plasma techniques. Modification procedures were chosen in a way to obtain high reproducibility with a minimum of time consumption. The idea behind this is a complete regeneration of a microarray printhead before or after usage to achieve best printing results over a typical print job. A sequence of low-pressure oxygen-plasma and plasma polymerization with hexamethyldisiloxane (HMDSO) was used to regenerate printheads. Proof of the concept is given through quality control performed with a spotter implemented CCD camera, contact angle measurements and a typical hybridization experiment. Stable printing results were obtained over 3000 activations showing that the presented method is suitable for treatment of microarray printheads.
Author details: | Matthias Grießner, Dave Hartig, Alexander Christmann, Eva Ehrentreich-Förster, Axel WarsinkeGND, Frank Fabian BierORCiDGND |
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URL: | http://iopscience.iop.org/0960-1317/ |
DOI: | https://doi.org/10.1088/0960-1317/20/3/037002 |
ISSN: | 0960-1317 |
Publication type: | Article |
Language: | English |
Year of first publication: | 2010 |
Publication year: | 2010 |
Release date: | 2017/03/25 |
Source: | Journal of micromechanics and microengineering. - ISSN 0960-1317. - 20 (2010), 3, Art. 037002 |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
Peer review: | Referiert |