Enzyme electrode for aromatic compounds exploiting the catalytic activities of microperoxidase-11
- Microperoxidase-11 (MR-11) which has been immobilised in a matrix of chitosan-embedded gold nanoparticles on the surface of a glassy carbon electrode catalyzes the conversion of aromatic substances. This peroxide-dependent catalysis of microperoxidase has been applied in an enzyme electrode for the first time to indicate aromatic compounds such as aniline. 4-fluoroaniline, catechol and p-aminophenol. The electrode signal is generated by the cathodic reduction of the quinone or quinoneimine which is formed in the presence of both MP-II and peroxide from the substrate. The same sensor principle will be extended to aromatic drugs.
Author details: | Aysu YarmanORCiDGND, Artavazd BadalyanORCiDGND, Nenad Gajovic-Eichelmann, Ursula WollenbergerORCiDGND, Frieder W. SchellerORCiDGND |
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DOI: | https://doi.org/10.1016/j.bios.2011.09.004 |
ISSN: | 0956-5663 |
Title of parent work (English): | Biosensors and bioelectronics : the principal international journal devoted to research, design development and application of biosensors and bioelectronics |
Publisher: | Elsevier |
Place of publishing: | Oxford |
Publication type: | Article |
Language: | English |
Year of first publication: | 2011 |
Publication year: | 2011 |
Release date: | 2017/03/26 |
Tag: | 4-Fluoroaniline; Aniline; Biosensors; Catechol; Microperoxidase-11; Nanoparticles; p-Aminophenol |
Volume: | 30 |
Issue: | 1 |
Number of pages: | 4 |
First page: | 320 |
Last Page: | 323 |
Funding institution: | BMBF of Germany [0311993]; Deutsche Forschungsgemeinschaft (DFG) within the German Excellence Initiative [EXC 314] |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
Peer review: | Referiert |