The identification of a novel protein involved in Molybdenum Cofactor Biosynthesis in Escherichia coli
- Background: In Moco biosynthesis, sulfur is transferred from L-cysteine to MPT synthase, catalyzing the conversion of cPMP to MPT. Results: The rhodanese-like protein YnjE is a novel protein involved in Moco biosynthesis. Conclusion: YnjE enhances the rate of conversion of cPMP to MPT and interacts with MoeB and IscS. S ignificance: To understand the mechanism of sulfur transfer and the role of rhodaneses in the cell.
Author details: | Jan-Ulrik DahlORCiD, Alexander Urban, Andrea Bolte, Promjit Sriyabhaya, Janet L. Donahue, Manfred Nimtz, Timothy J. Larson, Silke LeimkühlerORCiDGND |
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DOI: | https://doi.org/10.1074/jbc.M111.282368 |
ISSN: | 0021-9258 |
Title of parent work (English): | The journal of biological chemistry |
Publisher: | American Society for Biochemistry and Molecular Biology |
Place of publishing: | Bethesda |
Publication type: | Article |
Language: | English |
Year of first publication: | 2011 |
Publication year: | 2011 |
Release date: | 2017/03/26 |
Volume: | 286 |
Issue: | 41 |
Number of pages: | 12 |
First page: | 35801 |
Last Page: | 35812 |
Funding institution: | Deutsche Forschungsgemeinschaft [LE1171/5-3]; Thomas F. Jeffress and Kate Miller Jeffress Memorial Trust |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
Peer review: | Referiert |