voice break as the marker of biological age
- Aim: We aimed to develop the first references for body height, body weight and body mass index (BMI) for boys based on the individual developmental tempo with respect to their voice break status. Methods: We re-analysed data from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS study) on body height, body weight and body mass index based on the voice break, or mutation, in 3956 boys aged 10-17 years. We used the LMS method to construct smoothed references centiles for the studied variables in premutational, mutational and postmutational boys. Results: Body height, body weight and BMI differed significantly (p < 0.001) between the different stages of voice break. On average, boys were 5.9 cm taller, 5.8 kg heavier and had a 0.7 kg/m(2) higher BMI with every higher stage of voice break. Currently used growth references for chronological age in comparison with maturity-related references led to an average of 5.4% of boys being falsely classified as overweight.
| Author details: | Rebekka MummORCiDGND, Michael HermanussenORCiDGND, Christiane SchefflerORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1111/apa.13488 |
| ISSN: | 0803-5253 |
| ISSN: | 1651-2227 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/27242320 |
| Title of parent work (English): | Acta paediatrica : nurturing the child |
| Publisher: | Wiley-Blackwell |
| Place of publishing: | Hoboken |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2016 |
| Publication year: | 2016 |
| Release date: | 2020/03/22 |
| Tag: | Body mass index; Developmental tempo; Growth reference values; Overweight; Voice break |
| Volume: | 105 |
| Number of pages: | 5 |
| First page: | e459 |
| Last Page: | e463 |
| Funding institution: | Auxological Society (Deutsche Gesellschaft fur Auxologie) |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
| Peer review: | Referiert |
