Jian Li, Yong-Ping Lu, Oleg Tsuprykov, Ahmed Abdallah Abdalrahman Mohamed Hasan, Christoph Reichetzeder, Mei Tian, Xiao Li Zhang, Qin Zhang, Guo-Ying Sun, Jingli Guo, Mohamed Mahmoud Salem Ahmed Gaballa, Xiao-Ning Peng, Ge Lin, Berthold Hocher
- Aims/hypothesis Paternal high-fat diet prior to mating programmes impaired glucose tolerance in female offspring. We examined whether the metabolic consequences in offspring could be abolished by folate treatment of either the male rats before mating or the corresponding female rats during pregnancy. Methods Male F0 rats were fed either control diet or high-fat, high-sucrose and high-salt diet (HFSSD), with or without folate, before mating. Male rats were mated with control-diet-fed dams. After mating, the F0 dams were fed control diet with or without folate during pregnancy.
Metadaten| Author details: | Jian Li, Yong-Ping Lu, Oleg TsuprykovGND, Ahmed Abdallah Abdalrahman Mohamed HasanORCiDGND, Christoph ReichetzederORCiDGND, Mei Tian, Xiao Li Zhang, Qin Zhang, Guo-Ying Sun, Jingli Guo, Mohamed Mahmoud Salem Ahmed GaballaORCiDGND, Xiao-Ning Peng, Ge Lin, Berthold HocherORCiDGND |
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| DOI: | https://doi.org/10.1007/s00125-018-4635-x |
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| ISSN: | 0012-186X |
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| ISSN: | 1432-0428 |
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| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/29777263 |
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| Title of parent work (English): | Diabetologia : journal of the European Association for the Study of Diabetes (EASD) |
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| Publisher: | Springer |
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| Place of publishing: | New York |
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| Publication type: | Article |
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| Language: | English |
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| Year of first publication: | 2018 |
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| Publication year: | 2018 |
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| Release date: | 2021/10/19 |
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| Tag: | Glucose tolerance; High-fat-sucrose-salt diet; Maternal folate treatment; Paternal programming |
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| Volume: | 61 |
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| Issue: | 8 |
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| Number of pages: | 15 |
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| First page: | 1862 |
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| Last Page: | 1876 |
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| Funding institution: | National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81300557]; Hunan Province Science and Technology Plan [2014SK3003]; Programme for Excellent Talents of Hunan Normal University [ET14106] |
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| Organizational units: | Humanwissenschaftliche Fakultät / Strukturbereich Kognitionswissenschaften / Department Sport- und Gesundheitswissenschaften |
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| DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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| Peer review: | Referiert |
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| Publishing method: | Open Access / Bronze Open-Access |
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