Cytokines for evaluation of chronic inflammatory status in ageing research
- Background: There is a growing interest in the role of inflammageing for chronic disease development. Cytokines are potent soluble immune mediators that can be used as target biomarkers of inflammageing; however, their measurement in human samples has been challenging. This study aimed to assess the reliability of a pro- and anti-inflammatory cytokine panel in a sample of healthy people measured with a novel electrochemiluminescent multiplex immunoassay platform (Meso Scale Discovery, MSD), and to characterize their associations with metabolic and inflammatory phenotypes.
Author details: | Liselot A. KoelmanORCiDGND, Olga Pivovarova-Ramich, Andreas F. H. PfeifferORCiDGND, Tilman GruneORCiDGND, Krasimira AleksandrovaORCiDGND |
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DOI: | https://doi.org/10.1186/s12979-019-0151-1 |
ISSN: | 1742-4933 |
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/31139232 |
Title of parent work (German): | Immunity & Ageing |
Subtitle (English): | reliability and phenotypic characterisation |
Publisher: | BMC |
Place of publishing: | London |
Publication type: | Article |
Language: | English |
Date of first publication: | 2019/05/21 |
Publication year: | 2019 |
Release date: | 2021/06/18 |
Tag: | Ageing; BMI; Biomarkers; Cytokines; Inflammaging; Multiplex platforms; Reliability |
Volume: | 16 |
Number of pages: | 12 |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft |
DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Peer review: | Referiert |
Publishing method: | Open Access / Gold Open-Access |
DOAJ gelistet |