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The identification of a novel protein involved in Molybdenum Cofactor Biosynthesis in Escherichia coli
- Background: In Moco biosynthesis, sulfur is transferred from L-cysteine to MPT synthase, catalyzing the conversion of cPMP to MPT. Results: The rhodanese-like protein YnjE is a novel protein involved in Moco biosynthesis. Conclusion: YnjE enhances the rate of conversion of cPMP to MPT and interacts with MoeB and IscS. S ignificance: To understand the mechanism of sulfur transfer and the role of rhodaneses in the cell.
| Author details: | Jan-Ulrik DahlORCiD, Alexander Urban, Andrea Bolte, Promjit Sriyabhaya, Janet L. Donahue, Manfred Nimtz, Timothy J. Larson, Silke LeimkühlerORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1074/jbc.M111.282368 |
| ISSN: | 0021-9258 |
| Title of parent work (English): | The journal of biological chemistry |
| Publisher: | American Society for Biochemistry and Molecular Biology |
| Place of publishing: | Bethesda |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2011 |
| Publication year: | 2011 |
| Release date: | 2017/03/26 |
| Volume: | 286 |
| Issue: | 41 |
| Number of pages: | 12 |
| First page: | 35801 |
| Last Page: | 35812 |
| Funding institution: | Deutsche Forschungsgemeinschaft [LE1171/5-3]; Thomas F. Jeffress and Kate Miller Jeffress Memorial Trust |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
| Peer review: | Referiert |
