Catalytic bio-chemo and bio-bio tandem oxidation reactions for amide and carboxylic acid synthesis
- A catalytic toolbox for three different water-based one-pot cascades to convert aryl alcohols to amides and acids and cyclic amines to lactams, involving combination of oxidative enzymes (monoamine oxidase, xanthine dehydrogenase, galactose oxidase and laccase) and chemical oxidants (TBHP or Cul(cat)/H2O2) at mild temperatures, is presented. Mutually compatible conditions were found to afford products in good to excellent yields.
| Author details: | Beatrice Bechi, Susanne Herter, Shane McKenna, Christopher Riley, Silke LeimkühlerORCiDGND, Nicholas J. Turner, Andrew J. Carnell |
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| DOI: | https://doi.org/10.1039/c4gc01321b |
| ISSN: | 1463-9262 |
| ISSN: | 1463-9270 |
| Title of parent work (English): | Green chemistry : an international journal and green chemistry resource |
| Publisher: | Royal Society of Chemistry |
| Place of publishing: | Cambridge |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2014 |
| Publication year: | 2014 |
| Release date: | 2017/03/27 |
| Volume: | 16 |
| Issue: | 10 |
| Number of pages: | 6 |
| First page: | 4524 |
| Last Page: | 4529 |
| Funding institution: | Engineering and Physical Sciences Research Council (EPSRC); Innovative Medicines Initiative [115360]; European Union |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
| Peer review: | Referiert |
