570 Biowissenschaften; Biologie
Refine
Has Fulltext
- no (179) (remove)
Year of publication
- 2017 (179) (remove)
Document Type
- Article (127)
- Doctoral Thesis (34)
- Other (8)
- Review (7)
- Habilitation Thesis (2)
- Part of a Book (1)
Is part of the Bibliography
- yes (179) (remove)
Keywords
- body height (3)
- community effect (3)
- phylogeny (3)
- Arabidopsis (2)
- Cyanobacteria (2)
- European bats (2)
- Mesenchymal stem cells (2)
- Myodes glareolus (2)
- Obesity (2)
- Phylogeography (2)
- Pregnancy (2)
- Southeast Asia (2)
- acid sphingomyelinase (2)
- alien species (2)
- ancient DNA (2)
- biogeography (2)
- ceramide (2)
- metabarcoding (2)
- monoclonal antibodies (2)
- secular trend (2)
- species richness (2)
- 2-deoxy-D-ribose-5-phosphate aldolase (1)
- AAP bacteria (1)
- Above-ground (1)
- Absorption kinetics (1)
- Actin cytoskeleton (1)
- Adaptive traits (1)
- Adipose tissue (1)
- African green monkeys (1)
- Agricultural landscape (1)
- Algeria (1)
- Aluminium (1)
- Aluminium adjuvants (1)
- Anthropogenic pollution (1)
- Antibody detection (1)
- Antigone vipio (1)
- Antisense agents (1)
- Apis mellifera (1)
- Apoptosis (1)
- Aquatic fungi (1)
- Arabidopsis thaliana (1)
- Archaea (1)
- Archival DNA (1)
- Argasidae (1)
- Argonaute 2 protein (1)
- Australia (1)
- Autotaxin (1)
- B lymphocytes (1)
- BMI (1)
- BPP (1)
- Bacteria (1)
- Bahamas (1)
- Bark beetle (1)
- Bats (1)
- Below-ground (1)
- Berlin (1)
- Beta-diversity (1)
- Biodiversity (1)
- Biofilm (1)
- Bluestain fungi (1)
- Brassicaceae (1)
- Callose (1)
- Camelus dromedarius (1)
- Campylomormyrus (1)
- Canidae (1)
- Canopy (1)
- Carbon isotopes (delta C-13) (1)
- Carbon preference index (CPI) (1)
- Cell polarity (1)
- Centrosome (1)
- Chlamydomonas acidophila (1)
- Chlorella vulgaris (1)
- Chlorophyceae (1)
- Chromatin (1)
- Chronic obstructive pulmonary disease (COPD) (1)
- Chytrids (1)
- Climatic legacy (1)
- Cognitive style (1)
- Community (1)
- Community assembly (1)
- Complex dynamics (1)
- Concept of lying (1)
- Continental air masses (1)
- Continuous renal replacement therapy (1)
- Core stability (1)
- Cutting frequency (1)
- DELLA proteins (1)
- DNA barcoding (1)
- DNA metabarcoding (1)
- DPP-4 (1)
- DPP-4 inhibitors (1)
- Dactylis glomerata (1)
- Definition of lying (1)
- Dehydration tolerance (1)
- Dictyostelium (1)
- Dietary Cholesterol (1)
- Digestive enzyme activity (1)
- Disturbance (1)
- Diversity (1)
- Drug discovery (1)
- Durchflusszytometrie (1)
- EMG (1)
- East Asian flyway (1)
- Eco-evolutionary dynamics (1)
- Ecophysiology on freshwater phytoplankton (1)
- Electric organ (1)
- Environmental filtering (1)
- Epithelial tube (1)
- Et-1 (1)
- Eukaryota (1)
- Europe (1)
- Europäische Fledermausarten (1)
- Exocrine gland (1)
- Experimental philosophy (1)
- Eye-tracking (1)
- FAK-MAPK (1)
- FASTAR (1)
- Fatty acids (1)
- Field experiment (1)
- Field margins (1)
- First trimester (1)
- Forest edge (1)
- Freshwater (1)
- Freshwater microbial communities (1)
- GLP-1 and SDF-1a (1)
- GTPase (1)
- GenBank (1)
- Gene expression (1)
- Germany (1)
- Global Naturalized Alien Flora (GloNAF) database (1)
- Glucose (1)
- Glucosinolates (1)
- Gradients (1)
- Growth faltering (1)
- Growth modelling (1)
- Grus japonensis (1)
- Grus monacha (1)
- Gut microbiota (1)
- H3K4 methylation (1)
- Habitat heterogeneity (1)
- Hapten (1)
- Haptene (1)
- Hedgerow (1)
- Height z-score (1)
- Hepatic insulin resistance (1)
- Herb layer (1)
- Herbicide exposure (1)
- Herbivores (1)
- Heterogeneity species diversity relationship (1)
- Heteroptera (1)
- Heterotrophy (1)
- Hill numbers (1)
- Hybridom (1)
- Hydrogen isotopes (delta D) (1)
- Hypertension (1)
- Immunfluoreszenz (1)
- Immunology (1)
- Immunosensor (1)
- In vitro dissolution (1)
- Insect (1)
- Insulin signaling (1)
- Integrase 1 (1)
- Intensive care (1)
- Intermittent cycles (1)
- Invagination (1)
- Ion channels (1)
- Ips typographus (1)
- Issue 119 (1)
- Ixodidae (1)
- JUB1 (1)
- Kupffer Cells (1)
- LPA(3) receptor subtype (1)
- Lactobacillus fermentum (1)
- Lactobacillus salivarius (1)
- Lake (1)
- Land-use history (1)
- Land-use legacy (1)
- Landscape (1)
- Landschaftsanalyse (1)
- Langmuir-Schaefer (1)
- Larix (1)
- Late Glacial and Holocene (1)
- Leopard cat (1)
- Leucogeranus leucogeranus (1)
- Leukotriene B4 (1)
- Light availability (1)
- Limiting similarity (1)
- Lipases (1)
- Long-term change (1)
- Low birth weight (1)
- Lying (1)
- LysM (1)
- Lysophosphatidic acid (1)
- MABC-2 (1)
- MAPK (1)
- MAPK phosphatase (1)
- MIS 5 to 1 (1)
- Management intensity (1)
- Marker (1)
- Mesostigmata (1)
- Meta-analysis (1)
- MiSpEx (1)
- Microplastics (1)
- Microtubules (1)
- Mitosis (1)
- Mixotrophy (1)
- Molecular phylogenetics (1)
- Molecularly imprinted polymers (1)
- Monoclonal antibody (1)
- Monte Carlo method (1)
- Multi-locus phylogeny (1)
- Multimedia learning (1)
- Multispecies coalescent (1)
- Muntjac (1)
- NMR-based metabolomics (1)
- NWEurope (1)
- Namibia (1)
- Naturschutz (1)
- New Guinea (1)
- Non-target terrestrial plants (1)
- Nonalcoholic Fatty Liver Disease (NAFLD) (1)
- Nonalcoholic Steatohepatitis (NASH) (1)
- Norway (1)
- Nosema spp. (1)
- Nucleosome occupancy (1)
- Nucleus (1)
- Nutrition (1)
- Nutritional quality (1)
- Nycteribiidae (1)
- Organogenesis (1)
- Osmotrophy (1)
- PAMP (1)
- PARAFAC (1)
- PLFA (1)
- PP2C phosphatase (1)
- Pharmacokinetics/Pharmacodynamics (1)
- Phase relationships (1)
- Photosynthesis (1)
- Phylogenetics (1)
- PlGF (1)
- Plant chemical defense (1)
- Plant community (1)
- Plant community modelling (1)
- Plant diversity (1)
- Plant functional trait (1)
- Plant-community composition (1)
- Plant-soil feedback (1)
- Poecile hypermelaenus (1)
- Poecile weigoldicus (1)
- Polish conscripts (1)
- Polycomb (1)
- Pond (1)
- Population dynamics (1)
- Precipitation (1)
- Predator-prey cycles (1)
- Priming (1)
- Protein carbonylation (1)
- Proteomic (1)
- Pseudomonas syringae (1)
- Puumala virus seroprevalence (1)
- RBP4 (1)
- RNA (1)
- RNA Imaging (1)
- Rank-abundance (1)
- Rarity (1)
- Redistributive land reform (1)
- Renal function (1)
- Resistant starch (1)
- Resurvey (1)
- Retinol (1)
- Risk assessment tool (1)
- Rubisco (1)
- Secular height trend (1)
- Secular trend (1)
- Sediment (1)
- Seedlings (1)
- Short-term drought (1)
- Siphonaptera (1)
- Size exclusion chromatography (SEC) (1)
- Small for gestational age (1)
- Small-molecule miRNA modulators (1)
- Snakes (1)
- Space use (1)
- Species co-existence (1)
- Species complex (1)
- Species loss (1)
- Split-belt treadmill (1)
- Stable isotopes (1)
- Staphylococcus aureus (1)
- Stature (1)
- Staurastromyces oculus (1)
- Staurastrum sp. (1)
- Storage effect (1)
- Strategic growth adjustment (1)
- Streblidae (1)
- Survival (1)
- TTR (1)
- Target attainment (1)
- Taxonomic assignment (1)
- Temperate forest (1)
- Toxicokinetic modelling (1)
- Transcriptional memory (1)
- Treated wastewater (1)
- Triticum aestivum L. (1)
- Turnover (1)
- Typical Western Diet (1)
- Verbalizer (1)
- Visualizer (1)
- Vitamin A (1)
- Warburg effect (1)
- Weakly electric fish (1)
- Westerlies (1)
- Wind turbines (1)
- adaptation (1)
- adipogenic differentiation (1)
- adipose tissue (1)
- adipose tissue regeneration (1)
- anti-oxidative response (1)
- antibacterial activity (1)
- antigen (1)
- asymmetric dimethylarginine (ADMA) (1)
- baboons (1)
- baps (1)
- benthic (1)
- berry development (1)
- beta diversity (1)
- beta-Lactam (1)
- bifunctional enzyme (1)
- biodiversity (1)
- biodiversity exploratories (1)
- biofilm (1)
- biomarkers of renal failure (1)
- biomimetic sensors (1)
- blood banking (1)
- brassinosteroid (1)
- caffeine (1)
- capsule formation (1)
- capture enrichment (1)
- children (1)
- chimeric transcription factors (1)
- chloro-ribosome (1)
- chromatin (1)
- climate change (1)
- co-function network (1)
- community effect on height (1)
- competitive resistance (1)
- complex I (1)
- conscripts (1)
- conservation (1)
- consumptive resistance (1)
- contrast-induced nephropathy (1)
- conventional agriculture (1)
- correlation (1)
- cranes (1)
- dam construction (1)
- dead Cas9 (1)
- defense genes (1)
- degraded DNA (1)
- developing brain (1)
- diabetic nephropathy (1)
- distribution (1)
- diyabc (1)
- early warning (1)
- electrochemistry (1)
- electropolymerization (1)
- electrospun scaffold (1)
- endophytes (1)
- ensemble prediction (1)
- enzyme catalysis (1)
- enzyme immobilization (1)
- epidemiology (1)
- epigenetics (1)
- extinct birds (1)
- extinction (1)
- farm productivity (1)
- fertilization (1)
- floodplain (1)
- flow cytometry (1)
- foreign body giant cells (1)
- forest specialists (1)
- four-dimensional tissue reconstruction (1)
- freshwater lakes (1)
- fruit (1)
- fundamental motor skills (1)
- fusion (1)
- galactolipids (1)
- gamma diversity (1)
- gelatin based scaffold (1)
- gene expression (1)
- gene function prediction (1)
- genetic resistance (1)
- gibberellic acid (1)
- grapevine (1)
- growth (1)
- habitat generalist (1)
- hantavirus (1)
- hapten (1)
- harmful algae (1)
- height (1)
- herbivory (1)
- heterogeneity (1)
- heterologous systems (1)
- high temperature (1)
- honey bee (1)
- hormonal pathways (1)
- host-pathogen coevolution (1)
- human-wildlife conflict (1)
- hunting (1)
- hybrid capture (1)
- hybridoma (1)
- hybridoma technology (1)
- hyperoxia (1)
- immunconjugate (1)
- immunofluorescence (1)
- in vivo study (1)
- individual body height (1)
- intrinsically disordered proteins (1)
- invasive species (1)
- invertebrate-derived (iDNA) (1)
- islands (1)
- iterative mapping (1)
- kindergarten children (1)
- konventionelle Landwirtschaft (1)
- l-cysteine desulfurase (1)
- lacustrine groundwater discharge (1)
- land use change (1)
- landscape analysis (1)
- late embryogenesis abundant proteins (1)
- latitudinal gradients (1)
- leaf economics (1)
- lean mass (1)
- life history (1)
- littoral (1)
- lncRNA (1)
- lung inflammation (1)
- mRNA Quantification (1)
- macrophytes (1)
- mainland (1)
- measure hormone contents (1)
- mesoporous materials (1)
- metabolomics/metabolite profiling (1)
- miRNA (1)
- microRNA-induced silencing complex (1)
- microarrays (1)
- microbial invasion (1)
- microclimate (1)
- microparticle (1)
- microperoxidase (1)
- microsatellites (1)
- microstructure (1)
- migration (1)
- mitochondria (1)
- mitochondrial genome (1)
- mitochondrial genome (mtDNA) (1)
- mitochondrial genomes (1)
- mitochondrial transformation (1)
- mitogenome (1)
- molybdenum cofactor (1)
- monoklonale Antikörper (1)
- movement barrier (1)
- mowing (1)
- mtDNA (1)
- museum specimens (1)
- myeloma cells (1)
- n-alkanes (1)
- natural selection (1)
- naturalized species (1)
- network (1)
- next-generation sequencing (1)
- normal weight obesity (1)
- nutrient availability (1)
- nutrient ratios (1)
- nutrients (1)
- nutritional components (1)
- ophenylenediamine (1)
- osmolytes (1)
- ovarian cancer (1)
- oxidative stress (1)
- palaeoenvironment (1)
- palaeogenomics (1)
- palaeontology (1)
- parasite (1)
- pastoralism (1)
- performance (1)
- periphyton (1)
- permafrost deposits (1)
- persulfide (1)
- phenotyping (1)
- phosphorus (1)
- photoheterotrophy (1)
- photosynthesis (1)
- phylogeography (1)
- phytoplankton (1)
- plant biology (1)
- plant functional traits (1)
- plant invasion (1)
- plant strategies (1)
- plastid transformation (1)
- platelets (1)
- poly(N-isopropylacrylamide) (1)
- poly(ether imide) (1)
- polymeric thin film (1)
- population trend (1)
- pre-school children (1)
- precondition (1)
- preterm infants (1)
- property rights (1)
- protein folding (1)
- protein-membrane interaction (1)
- pufM gene (1)
- rabbit (1)
- rabbit haemorrhagic disease virus (1)
- radiocarbon ages (1)
- regional floras (1)
- replacement (1)
- rhizosphere (1)
- ribosome assembly (1)
- sFlt-1 (1)
- salicylic acid (1)
- saproxylic beetles (1)
- scopoletin (1)
- sedaDNA (1)
- seed mass (1)
- seepage (1)
- simulation (1)
- single-nucleotide polymorphism (SNP) (1)
- skinfolds (1)
- smFISH (1)
- social signal (1)
- socioeconomic situation (1)
- soil microbiome (1)
- source-sink dynamics (1)
- spatial grain (1)
- species accumulation curve (1)
- species turnover (1)
- spectroelectrochemistry (1)
- sphingosine kinase-1 (1)
- storage (1)
- strategic growth adjustment (1)
- structure (1)
- sulfadiazine (1)
- sulfurtransferase (1)
- synthetic biology (1)
- synthetic circuits (1)
- tRNA (1)
- taxonomy (1)
- thiocarboxylate (1)
- thiolactone (1)
- thionucleosides (1)
- tobacco (1)
- tobramycin (1)
- tomato (1)
- transcription factor (1)
- transcription factors (1)
- transcriptional regulation (1)
- transfusion-related acute lung injury (1)
- translation (1)
- treeline (1)
- trnL (1)
- tyrosinase (1)
- urban ecology (1)
- variability (1)
- vascularization (1)
- water level (1)
- weight (1)
- zonobiome (1)
Rubisco catalyses the first step of CO2 assimilation into plant biomass. Despite its crucial role, it is notorious for its low catalytic rate and its tendency to fix O2 instead of CO2, giving rise to a toxic product that needs to be recycled in a process known as photorespiration. Since almost all our food supply relies on Rubisco, even small improvements in its specificity for CO2 could lead to an improvement of photosynthesis and ultimately, crop yield. In this work, we attempted to improve photosynthesis by decreasing photorespiration with an artificial CCM based on a fusion between Rubisco and a carbonic anhydrase (CA).
A preliminary set of plants contained fusions between one of two CAs, bCA1 and CAH3, and the N- or C-terminus of RbcL connected by a small flexible linker of 5 amino acids. Subsequently, further fusion proteins were created between RbcL C-terminus and bCA1/CAH3 with linkers of 14, 23, 32, and 41 amino acids. The transplastomic tobacco plants carrying fusions with bCA1 were able to grow autotrophically even with the shortest linkers, albeit at a low rate, and accumulated very low levels of the fusion protein. On the other hand, plants carrying fusions with CAH3 were autotrophic only with the longer linkers. The longest linker permitted nearly wild-type like growth of the plants carrying fusions with CAH3 and increased the levels of fusion protein, but also of smaller degradation products.
The fusion of catalytically inactive CAs to RbcL did not cause a different phenotype from the fusions with catalytically active CAs, suggesting that the selected CAs were not active in the fusion with RbcL or their activity did not have an effect on CO2 assimilation. However, fusions to RbcL did not abolish RbcL catalytic activity, as shown by the autotrophic growth, gas exchange and in vitro activity measurements. Furthermore, Rubisco carboxylation rate and specificity for CO2 was not altered in some of the fusion proteins, suggesting that despite the defect in RbcL folding or assembly caused by the fusions, the addition of 60-150 amino acids to RbcL does not affect its catalytic properties. On the contrary, most growth defects of the plants carrying RbcL-CA fusions are related to their reduced Rubisco content, likely caused by impaired RbcL folding or assembly. Finally, we found that fusions with RbcL C-terminus were better tolerated than with the N-terminus, and increasing the length of the linker relieved the growth impairment imposed by the fusion to RbcL. Together, the results of this work constitute considerable relevant findings for future Rubisco engineering.
Changes in body height throughout extended historic periods are very complex and dynamic processes. Thispilot study aimed to investigate the pattern of longitudinal height z-scores changes in children before and after entering kindergarten. In summer 2016, we measured height and weight of 32 children from 4 groups of two kindergartens aged 3–6 years. All ages were centered according to the age of entry into the kindergarten. For each child we determined mean z-scores for height before and after entering the kindergarten, and assessed the variances for each kindergarten group. Twenty-two children targeted in height z-scores towards average height of their respective kindergarten group, 10 children did not. Due to the small numbers, the convergence in height variance however, remained insignificant (chi-squared independence test, p = 0.127). Additional studies with larger sample sizes are needed to confirm this pilot study.
Analyse der Funktion der dualen Lokalisation der 3-Mercaptopyruvat Sulfurtransferase im Menschen
(2017)
An ‛Aukward’ tale
(2017)
One hundred and seventy-three years ago, the last two Great Auks, Pinguinus impennis, ever reliably seen were killed. Their internal organs can be found in the collections of the Natural History Museum of Denmark, but the location of their skins has remained a mystery. In 1999, Great Auk expert Errol Fuller proposed a list of five potential candidate skins in museums around the world. Here we take a palaeogenomic approach to test which—if any—of Fuller’s candidate skins likely belong to either of the two birds. Using mitochondrial genomes from the five candidate birds (housed in museums in Bremen, Brussels, Kiel, Los Angeles, and Oldenburg) and the organs of the last two known individuals, we partially solve the mystery that has been on Great Auk scholars’ minds for generations and make new suggestions as to the whereabouts of the still-missing skin from these two birds.
Background: Findings: Approximately 55 gigabases of raw sequence were generated. From this data we assembled 72 complete mitogenome sequences, with an average depth of coverage of 102.9x and 55.2x for modern samples and historical samples, respectively. This dataset represents 52 species, of which 30 species had no previous mitogenome data available. The mitogenomes were geotagged to their sampling location, where known, to display a detailed geographical distribution of the species. Conclusion:
We identified Alizarin Red S and other well known fluorescent dyes useful for the online detection of pyrophosphate in enzymatic assays, including the loop mediated isothermal amplification (LAMP) and polymerase chain reaction (PCR) assays. An iterative screening was used for a selected set of compounds to first secure enzyme compatibility, evaluate inorganic pyrophosphate sensitivity in the presence of manganese as quencher and optimize conditions for an online detection. Of the selected dyes, the inexpensive alizarin red S was found to selectively detect pyrophosphate under LAMP and PCR conditions and is superior with respect to its defined red-shifted spectrum, long shelf life and low toxicity. In addition, the newly identified properties may also be useful in other enzymatic assays which do not generate nucleic acids but are based on inorganic pyrophosphate. Finally, we propose that our screening method may provide a blueprint for rapid screening of compounds for detecting inorganic pyrophosphate.
Eighteen scientists met at Jurata, Poland, to discuss various aspects of the transition from adolescence to adulthood. This transition is a delicate period facing complex interactions between the adolescents and the social group they belong to. Social identity, group identification and identity signalling, but also stress affecting basal salivary cortisol rhythms, hypertension, inappropriate nutrition causing latent and manifest obesity, moreover, in developing and under-developed countries, parasitosis causing anaemia thereby impairing growth and development, are issues to be dealt with during this period of the human development. In addition, some new aspects of the association between weight, height and head circumference in the newborns were discussed, as well as intrauterine head growth and head circumference as health risk indicators.