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We introduce a simple approach extending the input language of Answer Set Programming (ASP) systems by multi-valued propositions. Our approach is implemented as a (prototypical) preprocessor translating logic programs with multi-valued propositions into logic programs with Boolean propositions only. Our translation is modular and heavily benefits from the expressive input language of ASP. The resulting approach, along with its implementation, allows for solving interesting constraint satisfaction problems in ASP, showing a good performance.
Logical modeling has been widely used to understand and expand the knowledge about protein interactions among different pathways. Realizing this, the caspo-ts system has been proposed recently to learn logical models from time series data. It uses Answer Set Programming to enumerate Boolean Networks (BNs) given prior knowledge networks and phosphoproteomic time series data. In the resulting sequence of solutions, similar BNs are typically clustered together. This can be problematic for large scale problems where we cannot explore the whole solution space in reasonable time. Our approach extends the caspo-ts system to cope with the important use case of finding diverse solutions of a problem with a large number of solutions. We first present the algorithm for finding diverse solutions and then we demonstrate the results of the proposed approach on two different benchmark scenarios in systems biology: (1) an artificial dataset to model TCR signaling and (2) the HPN-DREAM challenge dataset to model breast cancer cell lines.
We elaborate upon the theoretical foundations of a metric temporal extension of Answer Set Programming. In analogy to previous extensions of ASP with constructs from Linear Temporal and Dynamic Logic, we accomplish this in the setting of the logic of Here-and-There and its non-monotonic extension, called Equilibrium Logic. More precisely, we develop our logic on the same semantic underpinnings as its predecessors and thus use a simple time domain of bounded time steps. This allows us to compare all variants in a uniform framework and ultimately combine them in a common implementation.
A polynomial translation of logic programs with nested expressions into disjunctive logic programs
(2002)
ASP modulo CSP
(2012)
We present the hybrid ASP solver clingcon, combining the simple modeling language and the high performance Boolean solving capacities of Answer Set Programming (ASP) with techniques for using non-Boolean constraints from the area of Constraint Programming (CP). The new clingcon system features an extended syntax supporting global constraints and optimize statements for constraint variables. The major technical innovation improves the interaction between ASP and CP solver through elaborated learning techniques based on irreducible inconsistent sets. A broad empirical evaluation shows that these techniques yield a performance improvement of an order of magnitude.
Acyclicity constraints are prevalent in knowledge representation and applications where acyclic data structures such as DAGs and trees play a role. Recently, such constraints have been considered in the satisfiability modulo theories (SMT) framework, and in this paper we carry out an analogous extension to the answer set programming (ASP) paradigm. The resulting formalism, ASP modulo acyclicity, offers a rich set of primitives to express constraints related to recursive structures. In the technical results of the paper, we relate the new generalization with standard ASP by showing (i) how acyclicity extensions translate into normal rules, (ii) how weight constraint programs can be instrumented by acyclicity extensions to capture stability in analogy to unfounded set checking, and (iii) how the gap between supported and stable models is effectively closed in the presence of such an extension. Moreover, we present an efficient implementation of acyclicity constraints by incorporating a respective propagator into the state-of-the-art ASP solver CLASP. The implementation provides a unique combination of traditional unfounded set checking with acyclicity propagation. In the experimental part, we evaluate the interplay of these orthogonal checks by equipping logic programs with supplementary acyclicity constraints. The performance results show that native support for acyclicity constraints is a worthwhile addition, furnishing a complementary modeling construct in ASP itself as well as effective means for translation-based ASP solving.
Building biological models by inferring functional dependencies from experimental data is an important issue in Molecular Biology. To relieve the biologist from this traditionally manual process, various approaches have been proposed to increase the degree of automation. However, available approaches often yield a single model only, rely on specific assumptions, and/or use dedicated, heuristic algorithms that are intolerant to changing circumstances or requirements in the view of the rapid progress made in Biotechnology. Our aim is to provide a declarative solution to the problem by appeal to Answer Set Programming (ASP) overcoming these difficulties. We build upon an existing approach to Automatic Network Reconstruction proposed by part of the authors. This approach has firm mathematical foundations and is well suited for ASP due to its combinatorial flavor providing a characterization of all models explaining a set of experiments. The usage of ASP has several benefits over the existing heuristic algorithms. First, it is declarative and thus transparent for biological experts. Second, it is elaboration tolerant and thus allows for an easy exploration and incorporation of biological constraints. Third, it allows for exploring the entire space of possible models. Finally, our approach offers an excellent performance, matching existing, special-purpose systems.
We introduce formal proof systems based on tableau methods for analyzing computations in Answer Set Programming (ASP). Our approach furnishes fine-grained instruments for characterizing operations as well as strategies of ASP solvers. The granularity is detailed enough to capture a variety of propagation and choice methods of algorithms used for ASP solving, also incorporating SAT-based and conflict-driven learning approaches to some extent. This provides us with a uniform setting for identifying and comparing fundamental properties of ASP solving approaches. In particular, we investigate their proof complexities and show that the run-times of best-case computations can vary exponentially between different existing ASP solvers. Apart from providing a framework for comparing ASP solving approaches, our characterizations also contribute to their understanding by pinning down the constitutive atomic operations. Furthermore, our framework is flexible enough to integrate new inference patterns, and so to study their relation to existing ones. To this end, we generalize our approach and provide an extensible basis aiming at a modular incorporation of additional language constructs. This is exemplified by augmenting our basic tableau methods with cardinality constraints and disjunctions.