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Ambauen, Ladina ; Arnold, Maren ; Becker, Christian ; Chahrour, Mohamed Chaker ; Destanovic, Edis ; Fretter, Alexandra ; Geißler, Marc ; Grünberg, Uwe ; Habl, Moritz ; Hoffmann, Sandra ; Juchler, Ingo ; Jurkatis, Lena Christine ; Keitel, Bernhard ; Losensky, Nikolai ; Mrowietz, Christian ; Nadol, Dominic ; Naumann, Asja ; Ockenga, Imke ; Pohlandt, Anne ; Pürschel, Tobias ; Recktenwald, Michelle ; Stephan, Roswitha ; Tuchel, Johannes ; Weinkamp, Christina ; Weiß, Christian ; Wiecking, Ole ; Wockenfuß, Patricia ; Zalitatsch, Nora Lina
Mildred Harnack, geb. Fish, stammte ursprünglich aus Milwaukee, Wisconsin. Zusammen mit ihrem Ehemann Arvid Harnack zog sie nach Deutschland und lebte seit 1930 in Berlin. Hier lehrte die Literaturwissenschaftlerin an der Friedrich-Wilhelms-Universität (heute Humboldt-Universität) und am Berliner Abendgymnasium (heute Peter A. Silbermann-Schule). Bereits kurz nach der Machtübernahme von Adolf Hitler hatte sich um das Ehepaar Harnack ein Kreis von Freunden gebildet, der gegen die Herrschaft der Nationalsozialisten opponierte. Dazu zählten auch Karl Behrens und Bodo Schlösinger, die beide Schüler Mildred Harnacks am Berliner Abendgymnasium waren. Mildred Harnack konnte mit Hilfe ihrer Kontakte zur amerikanischen Botschaft ihren Schülern im nationalsozialistischen Deutschland ansonsten nicht zugängliche Informationen besorgen.
Aufgrund von Funkkontakten des Freundeskreises zur Sowjetunion wurde die Gruppe von den Nationalsozialisten Rote Kapelle genannt – „rot“ bezog sich auf deren linke Haltung und mit „Kapelle“ wurden Funker assoziiert, die wie Pianisten in einer Kapelle spielen. Der Berliner Oppositionszirkel umfasste bis zu seiner Zerschlagung durch die Nationalsozialisten etwa 150 Personen verschiedenster Berufsgruppen, unterschiedlicher parteipolitischer Einstellungen und Konfessionen. Die Gruppe verfertigte oppositionelle Flugblätter und lieferte Informationen an die amerikanische Botschaft sowie an die Sowjetunion. Mildred Harnack wurde – wie viele ihrer Mitstreiterinnen und Mitstreiter – nach ihrer Verhaftung vom Reichskriegsgericht zum Tode verurteilt und am 16. Februar 1943 in Plötzensee guillotiniert.
In diesem Band stellen Studierende der Universität Potsdam sowie Hörerinnen und Hörer der Peter A. Silbermann-Schule (Berlin) nach einem kurzen Überblick zum Widerstand gegen den Nationalsozialismus in Deutschland das Netzwerk der Roten Kapelle sowie die Biographien von Mildred Harnack und ihren Schülern Karl Behrens und Bodo Schlösinger vom Berliner Abendgymnasium eindrücklich vor.
Ambauen, Ladina ; Arnold, Maren ; Becker, Christian ; Chahrour, Mohamed Chaker ; Destanovic, Edis ; Fretter, Alexandra ; Geißler, Marc ; Grünberg, Uwe ; Habl, Moritz ; Hoffmann, Sandra ; Juchler, Ingo ; Jurkatis, Lena Christine ; Keitel, Bernhard ; Losensky, Nikolai ; Mrowietz, Christian ; Nadol, Dominic ; Naumann, Asja ; Ockenga, Imke ; Pohlandt, Anne ; Pürschel, Tobias ; Recktenwald, Michelle ; Stephan, Roswitha ; Tuchel, Johannes ; Weinkamp, Christina ; Weiß, Christian ; Wiecking, Ole ; Wockenfuß, Patricia ; Zalitatsch, Nora Lina
Mildred Harnack, geb. Fish, stammte ursprünglich aus Milwaukee, Wisconsin. Zusammen mit ihrem Ehemann Arvid Harnack zog sie nach Deutschland und lebte seit 1930 in Berlin. Hier lehrte die Literaturwissenschaftlerin an der Friedrich-Wilhelms-Universität (heute Humboldt-Universität) und am Berliner Abendgymnasium (heute Peter A. Silbermann-Schule). Bereits kurz nach der Machtübernahme von Adolf Hitler hatte sich um das Ehepaar Harnack ein Kreis von Freunden gebildet, der gegen die Herrschaft der Nationalsozialisten opponierte. Dazu zählten auch Karl Behrens und Bodo Schlösinger, die beide Schüler Mildred Harnacks am Berliner Abendgymnasium waren. Mildred Harnack konnte mit Hilfe ihrer Kontakte zur amerikanischen Botschaft ihren Schülern im nationalsozialistischen Deutschland ansonsten nicht zugängliche Informationen besorgen.
Aufgrund von Funkkontakten des Freundeskreises zur Sowjetunion wurde die Gruppe von den Nationalsozialisten Rote Kapelle genannt – „rot“ bezog sich auf deren linke Haltung und mit „Kapelle“ wurden Funker assoziiert, die wie Pianisten in einer Kapelle spielen. Der Berliner Oppositionszirkel umfasste bis zu seiner Zerschlagung durch die Nationalsozialisten etwa 150 Personen verschiedenster Berufsgruppen, unterschiedlicher parteipolitischer Einstellungen und Konfessionen. Die Gruppe verfertigte oppositionelle Flugblätter und lieferte Informationen an die amerikanische Botschaft sowie an die Sowjetunion. Mildred Harnack wurde – wie viele ihrer Mitstreiterinnen und Mitstreiter – nach ihrer Verhaftung vom Reichskriegsgericht zum Tode verurteilt und am 16. Februar 1943 in Plötzensee guillotiniert.
In diesem Band stellen Studierende der Universität Potsdam sowie Hörerinnen und Hörer der Peter A. Silbermann-Schule (Berlin) nach einem kurzen Überblick zum Widerstand gegen den Nationalsozialismus in Deutschland das Netzwerk der Roten Kapelle sowie die Biographien von Mildred Harnack und ihren Schülern Karl Behrens und Bodo Schlösinger vom Berliner Abendgymnasium eindrücklich vor.
Dengler, Jürgen ; Wagner, Viktoria ; Dembicz, Iwona ; Garcia-Mijangos, Itziar ; Naqinezhad, Alireza ; Boch, Steffen ; Chiarucci, Alessandro ; Conradi, Timo ; Filibeck, Goffredo ; Guarino, Riccardo ; Janisova, Monika ; Steinbauer, Manuel J. ; Acic, Svetlana ; Acosta, Alicia T. R. ; Akasaka, Munemitsu ; Allers, Marc-Andre ; Apostolova, Iva ; Axmanova, Irena ; Bakan, Branko ; Baranova, Alina ; Bardy-Durchhalter, Manfred ; Bartha, Sandor ; Baumann, Esther ; Becker, Thomas ; Becker, Ute ; Belonovskaya, Elena ; Bengtsson, Karin ; Benito Alonso, Jose Luis ; Berastegi, Asun ; Bergamini, Ariel ; Bonini, Ilaria ; Bruun, Hans Henrik ; Budzhak, Vasyl ; Bueno, Alvaro ; Antonio Campos, Juan ; Cancellieri, Laura ; Carboni, Marta ; Chocarro, Cristina ; Conti, Luisa ; Czarniecka-Wiera, Marta ; De Frenne, Pieter ; Deak, Balazs ; Didukh, Yakiv P. ; Diekmann, Martin ; Dolnik, Christian ; Dupre, Cecilia ; Ecker, Klaus ; Ermakov, Nikolai ; Erschbamer, Brigitta ; Escudero, Adrian ; Etayo, Javier ; Fajmonova, Zuzana ; Felde, Vivian A. ; Fernandez Calzado, Maria Rosa ; Finckh, Manfred ; Fotiadis, Georgios ; Fracchiolla, Mariano ; Ganeva, Anna ; Garcia-Magro, Daniel ; Gavilan, Rosario G. ; Germany, Markus ; Giladi, Itamar ; Gillet, Francois ; Giusso del Galdo, Gian Pietro ; Gonzalez, Jose M. ; Grytnes, John-Arvid ; Hajek, Michal ; Hajkova, Petra ; Helm, Aveliina ; Herrera, Mercedes ; Hettenbergerova, Eva ; Hobohm, Carsten ; Huellbusch, Elisabeth M. ; Ingerpuu, Nele ; Jandt, Ute ; Jeltsch, Florian ; Jensen, Kai ; Jentsch, Anke ; Jeschke, Michael ; Jimenez-Alfaro, Borja ; Kacki, Zygmunt ; Kakinuma, Kaoru ; Kapfer, Jutta ; Kavgaci, Ali ; Kelemen, Andras ; Kiehl, Kathrin ; Koyama, Asuka ; Koyanagi, Tomoyo F. ; Kozub, Lukasz ; Kuzemko, Anna ; Kyrkjeeide, Magni Olsen ; Landi, Sara ; Langer, Nancy ; Lastrucci, Lorenzo ; Lazzaro, Lorenzo ; Lelli, Chiara ; Leps, Jan ; Loebel, Swantje ; Luzuriaga, Arantzazu L. ; Maccherini, Simona ; Magnes, Martin ; Malicki, Marek ; Marceno, Corrado ; Mardari, Constantin ; Mauchamp, Leslie ; May, Felix ; Michelsen, Ottar ; Mesa, Joaquin Molero ; Molnar, Zsolt ; Moysiyenko, Ivan Y. ; Nakaga, Yuko K. ; Natcheva, Rayna ; Noroozi, Jalil ; Pakeman, Robin J. ; Palpurina, Salza ; Partel, Meelis ; Paetsch, Ricarda ; Pauli, Harald ; Pedashenko, Hristo ; Peet, Robert K. ; Pielech, Remigiusz ; Pipenbaher, Natasa ; Pirini, Chrisoula ; Pleskova, Zuzana ; Polyakova, Mariya A. ; Prentice, Honor C. ; Reinecke, Jennifer ; Reitalu, Triin ; Pilar Rodriguez-Rojo, Maria ; Rolecek, Jan ; Ronkin, Vladimir ; Rosati, Leonardo ; Rosen, Ejvind ; Ruprecht, Eszter ; Rusina, Solvita ; Sabovljevic, Marko ; Maria Sanchez, Ana ; Savchenko, Galina ; Schuhmacher, Oliver ; Skornik, Sonja ; Sperandii, Marta Gaia ; Staniaszek-Kik, Monika ; Stevanovic-Dajic, Zora ; Stock, Marin ; Suchrow, Sigrid ; Sutcliffe, Laura M. E. ; Swacha, Grzegorz ; Sykes, Martin ; Szabo, Anna ; Talebi, Amir ; Tanase, Catalin ; Terzi, Massimo ; Tolgyesi, Csaba ; Torca, Marta ; Torok, Peter ; Tothmeresz, Bela ; Tsarevskaya, Nadezda ; Tsiripidis, Ioannis ; Tzonev, Rossen ; Ushimaru, Atushi ; Valko, Orsolya ; van der Maarel, Eddy ; Vanneste, Thomas ; Vashenyak, Iuliia ; Vassilev, Kiril ; Viciani, Daniele ; Villar, Luis ; Virtanen, Risto ; Kosic, Ivana Vitasovic ; Wang, Yun ; Weiser, Frank ; Went, Julia ; Wesche, Karsten ; White, Hannah ; Winkler, Manuela ; Zaniewski, Piotr T. ; Zhang, Hui ; Ziv, Yaron ; Znamenskiy, Sergey ; Biurrun, Idoia
GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board.
Gulbins, Erich ; Palmada, Monica ; Reichel, Martin ; Lueth, Anja ; Boehmer, Christoph ; Amato, Davide ; Mueller, Christian P. ; Tischbirek, Carsten H. ; Groemer, Teja W. ; Tabatabai, Ghazaleh ; Becker, Katrin Anne ; Tripal, Philipp ; Staedtler, Sven ; Ackermann, Teresa F. ; van Brederode, Johannes ; Alzheimer, Christian ; Weller, Michael ; Lang, Undine E. ; Kleuser, Burkhard ; Grassme, Heike ; Kornhuber, Johannes
Major depression is a highly prevalent severe mood disorder that is treated with antidepressants. The molecular targets of antidepressants require definition. We investigated the role of the acid sphingomyelinase (Asm)-ceramide system as a target for antidepressants. Therapeutic concentrations of the antidepressants amitriptyline and fluoxetine reduced Asm activity and ceramide concentrations in the hippocampus, increased neuronal proliferation, maturation and survival and improved behavior in mouse models of stress-induced depression. Genetic Asm deficiency abrogated these effects. Mice overexpressing Asm, heterozygous for acid ceramidase, treated with blockers of ceramide metabolism or directly injected with C16 ceramide in the hippocampus had higher ceramide concentrations and lower rates of neuronal proliferation, maturation and survival compared with controls and showed depression-like behavior even in the absence of stress. The decrease of ceramide abundance achieved by antidepressant-mediated inhibition of Asm normalized these effects. Lowering ceramide abundance may thus be a central goal for the future development of antidepressants.
We study Cheeger-Simons differential characters and provide geometric descriptions of the ring structure and of the fiber integration map. The uniqueness of differential cohomology (up to unique natural transformation) is proved by deriving an explicit formula for any natural transformation between a differential cohomology theory and the model given by differential characters. Fiber integration for fibers with boundary is treated in the context of relative differential characters. As applications we treat higher-dimensional holonomy, parallel transport, and transgression.
Diekmann, Martin ; Andres, Christian ; Becker, Thomas ; Bennie, Jonathan ; Blueml, Volker ; Bullock, James M. ; Culmsee, Heike ; Fanigliulo, Miriam ; Hahn, Annett ; Heinken, Thilo ; Leuschner, Christoph ; Luka, Stefanie ; Meissner, Justus ; Müller, Josef ; Newton, Adrian ; Peppler-Lisbach, Cord ; Rosenthal, Gert ; van den Berg, Leon J. L. ; Vergeer, Philippine ; Wesche, Karsten
Questions Has plant species richness in semi-natural grasslands changed over recent decades? Do the temporal trends of habitat specialists differ from those of habitat generalists? Has there been a homogenization of the grassland vegetation? Location Different regions in Germany and the UK. Methods We conducted a formal meta-analysis of re-survey vegetation studies of semi-natural grasslands. In total, 23 data sets were compiled, spanning up to 75 years between the surveys, including 13 data sets from wet grasslands, six from dry grasslands and four from other grassland types. Edaphic conditions were assessed using mean Ellenberg indicator values for soil moisture, nitrogen and pH. Changes in species richness and environmental variables were evaluated using response ratios. Results In most wet grasslands, total species richness declined over time, while habitat specialists almost completely vanished. The number of species losses increased with increasing time between the surveys and were associated with a strong decrease in soil moisture and higher soil nutrient contents. Wet grasslands in nature reserves showed no such changes or even opposite trends. In dry grasslands and other grassland types, total species richness did not consistently change, but the number or proportions of habitat specialists declined. There were also considerable changes in species composition, especially in wet grasslands that often have been converted into intensively managed, highly productive meadows or pastures. We did not find a general homogenization of the vegetation in any of the grassland types. Conclusions The results document the widespread deterioration of semi-natural grasslands, especially of those types that can easily be transformed to high production grasslands. The main causes for the loss of grassland specialists are changed management in combination with increased fertilization and nitrogen deposition. Dry grasslands are most resistant to change, but also show a long-term trend towards an increase in more mesotrophic species.
Posovszky, Carsten ; Roesler, Vreni Helen ; Becker, Sebastian ; Iven, Enno ; Hudert, Christian ; Ebinger, Friedrich ; Calvano, Claudia ; Warschburger, Petra
Intolerance to lactose or fructose is frequently diagnosed in children with chronic abdominal pain (CAP). However, the causal relationship remains a matter of discussion. A cohort of 253 patients, aged 7-12 years, presenting with unexplained CAP received standardized diagnostics. Additional diagnostic tests were performed based on their medical history and physical and laboratory investigations. Fructose and lactose hydrogen breath tests (H2BT) as well as empiric diagnostic elimination diets were performed in 135 patients reporting abdominal pain related to the consumption of lactose or fructose to evaluate carbohydrate intolerance as a potential cause of CAP. Carbohydrate malabsorption by H2BT was found in 55 (41%) out of 135 patients. An abnormal increase in H2BT was revealed in 30% (35/118) of patients after fructose consumption and in 18% (20/114) of patients after lactose administration. Forty-six percent (25/54) reported pain relief during a diagnostic elimination diet. In total, 17 patients had lactose malabsorption, 29 fructose malabsorption, and nine combined carbohydrate malabsorption. Carbohydrate intolerance as a cause of CAP was diagnosed at follow-up in only 18% (10/55) of patients with malabsorption after the elimination of the respective carbohydrate. Thus, carbohydrate malabsorption appears to be an incidental finding in children with functional abdominal pain disorders, rather than its cause. Therefore, testing of carbohydrate intolerance should only be considered in children with a strong clinical suspicion and with the goal to prevent long-term unnecessary dietary restrictions in children suffering from CAP.
Abdalla, Hassan E. ; Abramowski, Attila ; Aharonian, Felix A. ; Benkhali, Faiçal Ait ; Akhperjanian, A. G. ; Angüner, Ekrem Oǧuzhan ; Arrieta, M. ; Aubert, Pierre ; Backes, Michael ; Balzer, Arnim ; Barnard, Michelle ; Becherini, Yvonne ; Tjus, Julia Becker ; Berge, David ; Bernhard, Sabrina ; Bernlöhr, K. ; Birsin, E. ; Blackwell, R. ; Bottcher, Markus ; Boisson, Catherine ; Bolmont, J. ; Bordas, Pol ; Bregeon, Johan ; Brun, Francois ; Brun, Pierre ; Bryan, Mark ; Bulik, Tomasz ; Capasso, M. ; Carr, John ; Casanova, Sabrina ; Chakraborty, N. ; Chalme-Calvet, R. ; Chaves, Ryan C. G. ; Chen, Andrew ; Chevalier, J. ; Chretien, M. ; Colafrancesco, Sergio ; Cologna, Gabriele ; Condon, B. ; Conrad, Jan ; Couturier, C. ; Cui, Y. ; Davids, I. D. ; Degrange, B. ; Deil, Christoph ; deWilt, P. ; Djannati-Atai, Arache ; Domainko, Wilfried ; Donath, Axel ; Dubus, Guillaume ; Dutson, Kate ; Dyks, J. ; Dyrda, M. ; Edwards, T. ; Egberts, Kathrin ; Eger, P. ; Ernenwein, J. -P. ; Eschbach, S. ; Farnier, C. ; Fegan, Stuart ; Fernandes, M. V. ; Fiasson, A. ; Fontaine, G. ; Foerster, A. ; Funk, S. ; Füßling, Matthias ; Gabici, Stefano ; Gajdus, M. ; Gallant, Y. A. ; Garrigoux, T. ; Giavitto, Gianluca ; Giebels, B. ; Glicenstein, J. F. ; Gottschall, Daniel ; Goyal, A. ; Grondin, M. -H. ; Grudzinska, M. ; Hadasch, Daniela ; Hahn, J. ; Hawkes, J. ; Heinzelmann, G. ; Henri, Gilles ; Hermann, G. ; Hervet, Olivier ; Hillert, A. ; Hinton, James Anthony ; Hofmann, Werner ; Hoischen, Clemens ; Holler, M. ; Horns, D. ; Ivascenko, Alex ; Jacholkowska, A. ; Jamrozy, Marek ; Janiak, M. ; Jankowsky, D. ; Jankowsky, Felix ; Jingo, M. ; Jogler, Tobias ; Jouvin, Lea ; Jung-Richardt, Ira ; Kastendieck, M. A. ; Katarzynski, Krzysztof ; Katz, Uli ; Kerszberg, D. ; Khelifi, B. ; Kieffer, M. ; King, J. ; Klepser, S. ; Klochkov, Dmitry ; Kluzniak, W. ; Kolitzus, D. ; Komin, Nu. ; Kosack, K. ; Krakau, S. ; Kraus, Michael ; Krayzel, F. ; Kruger, P. P. ; Laffon, H. ; Lamanna, G. ; Lau, Jeanie ; Lees, J. -P. ; Lefaucheur, J. ; Lefranc, V. ; Lemiere, A. ; Lemoine-Goumard, M. ; Lenain, J. -P. ; Leser, Eva ; Lohse, Thomas ; Lorentz, M. ; Lui, R. ; Lypova, Iryna ; Marandon, Vincent ; Marcowith, Alexandre ; Mariaud, C. ; Marx, R. ; Maurin, G. ; Maxted, N. ; Mayer, Michael ; Meintjes, Petrus Johannes ; Menzler, U. ; Meyer, Manuel ; Mitchell, A. M. W. ; Moderski, R. ; Mohamed, M. ; Mora, K. ; Moulin, E. ; Murach, T. ; de Naurois, Mathieu ; Niederwanger, F. ; Niemiec, J. ; Oakes, L. ; Odaka, Hirokazu ; Ohm, Stefan ; Oettl, S. ; Ostrowski, M. ; Oya, I. ; Padovani, Marco ; Panter, M. ; Parsons, R. D. ; Arribas, M. Paz ; Pekeur, N. W. ; Pelletier, G. ; Petrucci, P. -O. ; Peyaud, B. ; Pita, S. ; Poon, Helen ; Prokhorov, Dmitry ; Prokoph, Heike ; Puehlhofer, Gerd ; Punch, Michael ; Quirrenbach, Andreas ; Raab, S. ; Reimer, Anita ; Reimer, Olaf ; Renaud, M. ; de los Reyes, R. ; Rieger, Frank ; Romoli, Carlo ; Rosier-Lees, S. ; Rowell, G. ; Rudak, B. ; Rulten, C. B. ; Sahakian, V. ; Salek, David ; Sanchez, David A. ; Santangelo, Andrea ; Sasaki, Manami ; Schlickeiser, Reinhard ; Schussler, F. ; Schulz, Andreas ; Schwanke, U. ; Schwemmer, S. ; Seyffert, A. S. ; Shafi, N. ; Simoni, R. ; Sol, H. ; Spanier, Felix ; Spengler, G. ; Spiess, F. ; Stawarz, Lukasz ; Steenkamp, R. ; Stegmann, Christian ; Stinzing, F. ; Stycz, K. ; Sushch, Iurii ; Tavernet, J. -P. ; Tavernier, T. ; Taylor, A. M. ; Terrier, R. ; Tluczykont, Martin ; Trichard, C. ; Tuffs, R. ; van der Walt, Johan ; van Eldik, Christopher ; van Soelen, Brian ; Vasileiadis, Georges ; Veh, J. ; Venter, C. ; Viana, A. ; Vincent, P. ; Vink, Jacco ; Voisin, F. ; Voelk, Heinrich J. ; Vuillaume, Thomas ; Wadiasingh, Z. ; Wagner, Stefan J. ; Wagner, P. ; Wagner, R. M. ; White, R. ; Wierzcholska, Alicja ; Willmann, P. ; Woernlein, A. ; Wouters, Denis ; Yang, R. ; Zabalza, Victor ; Zaborov, D. ; Zacharias, M. ; Zdziarski, A. A. ; Zech, Andreas ; Zefi, F. ; Ziegler, A. ; Zywucka, Natalia
The inner region of the Milky Way halo harbors a large amount of dark matter (DM). Given its proximity, it is one of the most promising targets to look for DM. We report on a search for the annihilations of DM particles using gamma-ray observations towards the inner 300 pc of the Milky Way, with the H.E.S.S. array of ground-based Cherenkov telescopes. The analysis is based on a 2D maximum likelihood method using Galactic Center (GC) data accumulated by H.E.S.S. over the last 10 years (2004-2014), and does not show any significant gamma-ray signal above background. Assuming Einasto and Navarro-Frenk-White DM density profiles at the GC, we derive upper limits on the annihilation cross section <sigma nu >. These constraints are the strongest obtained so far in the TeV DM mass range and improve upon previous limits by a factor 5. For the Einasto profile, the constraints reach <sigma nu > values of 6 x 10(-26) cm(3) s(-1) in the W+W- channel for a DM particle mass of 1.5 TeV, and 2 x 10(-26) cm(3) s(-1) in the tau(+)tau(-) channel for a 1 TeV mass. For the first time, ground-based gamma-ray observations have reached sufficient sensitivity to probe <sigma nu > values expected from the thermal relic density for TeV DM particles.
In this thesis, we give two constructions for Riemannian metrics on Seiberg-Witten moduli spaces. Both these constructions are naturally induced from the L2-metric on the configuration space. The construction of the so called quotient L2-metric is very similar to the one construction of an L2-metric on Yang-Mills moduli spaces as given by Groisser and Parker. To construct a Riemannian metric on the total space of the Seiberg-Witten bundle in a similar way, we define the reduced gauge group as a subgroup of the gauge group. We show, that the quotient of the premoduli space by the reduced gauge group is isomorphic as a U(1)-bundle to the quotient of the premoduli space by the based gauge group. The total space of this new representation of the Seiberg-Witten bundle carries a natural quotient L2-metric, and the bundle projection is a Riemannian submersion with respect to these metrics. We compute explicit formulae for the sectional curvature of the moduli space in terms of Green operators of the elliptic complex associated with a monopole. Further, we construct a Riemannian metric on the cobordism between moduli spaces for different perturbations. The second construction of a Riemannian metric on the moduli space uses a canonical global gauge fixing, which represents the total space of the Seiberg-Witten bundle as a finite dimensional submanifold of the configuration space. We consider the Seiberg-Witten moduli space on a simply connected Käuhler surface. We show that the moduli space (when nonempty) is a complex projective space, if the perturbation does not admit reducible monpoles, and that the moduli space consists of a single point otherwise. The Seiberg-Witten bundle can then be identified with the Hopf fibration. On the complex projective plane with a special Spin-C structure, our Riemannian metrics on the moduli space are Fubini-Study metrics. Correspondingly, the metrics on the total space of the Seiberg-Witten bundle are Berger metrics. We show that the diameter of the moduli space shrinks to 0 when the perturbation approaches the wall of reducible perturbations. Finally we show, that the quotient L2-metric on the Seiberg-Witten moduli space on a Kähler surface is a Kähler metric.
Dorenkamp, Marc ; Bonaventura, Klaus ; Sohns, Christian ; Becker, Christoph R. ; Leber, Alexander W.
Aims The study aims to determine the direct costs and comparative cost-effectiveness of latest-generation dual-source computed tomography (DSCT) and invasive coronary angiography for diagnosing coronary artery disease (CAD) in patients suspected of having this disease.
Methods The study was based on a previously elaborated cohort with an intermediate pretest likelihood for CAD and on complementary clinical data. Cost calculations were based on a detailed analysis of direct costs, and generally accepted accounting principles were applied. Based on Bayes' theorem, a mathematical model was used to compare the cost-effectiveness of both diagnostic approaches. Total costs included direct costs, induced costs and costs of complications. Effectiveness was defined as the ability of a diagnostic test to accurately identify a patient with CAD.
Results Direct costs amounted to (sic)98.60 for DSCT and to (sic)317.75 for invasive coronary angiography. Analysis of model calculations indicated that cost-effectiveness grew hyperbolically with increasing prevalence of CAD. Given the prevalence of CAD in the study cohort (24%), DSCT was found to be more cost-effective than invasive coronary angiography ((sic)970 vs (sic)1354 for one patient correctly diagnosed as having CAD). At a disease prevalence of 49%, DSCT and invasive angiography were equally effective with costs of (sic)633. Above a threshold value of disease prevalence of 55%, proceeding directly to invasive coronary angiography was more cost-effective than DSCT.
Conclusions With proper patient selection and consideration of disease prevalence, DSCT coronary angiography is cost-effective for diagnosing CAD in patients with an intermediate pretest likelihood for it. However, the range of eligible patients may be smaller than previously reported.
We study differential cohomology on categories of globally hyperbolic Lorentzian manifolds. The Lorentzian metric allows us to define a natural transformation whose kernel generalizes Maxwell's equations and fits into a restriction of the fundamental exact sequences of differential cohomology. We consider smooth Pontryagin duals of differential cohomology groups, which are subgroups of the character groups. We prove that these groups fit into smooth duals of the fundamental exact sequences of differential cohomology and equip them with a natural presymplectic structure derived from a generalized Maxwell Lagrangian. The resulting presymplectic Abelian groups are quantized using the CCR-functor, which yields a covariant functor from our categories of globally hyperbolic Lorentzian manifolds to the category of C∗-algebras. We prove that this functor satisfies the causality and time-slice axioms of locally covariant quantum field theory, but that it violates the locality axiom. We show that this violation is precisely due to the fact that our functor has topological subfunctors describing the Pontryagin duals of certain singular cohomology groups. As a byproduct, we develop a Fréchet–Lie group structure on differential cohomology groups.
By adapting the Cheeger-Simons approach to differential cohomology, we establish a notion of differential cohomology with compact support. We show that it is functorial with respect to open embeddings and that it fits into a natural diagram of exact sequences which compare it to compactly supported singular cohomology and differential forms with compact support, in full analogy to ordinary differential cohomology. We prove an excision theorem for differential cohomology using a suitable relative version. Furthermore, we use our model to give an independent proof of Pontryagin duality for differential cohomology recovering a result of [Harvey, Lawson, Zweck - Amer. J. Math. 125 (2003), 791]: On any oriented manifold, ordinary differential cohomology is isomorphic to the smooth Pontryagin dual of compactly supported differential cohomology. For manifolds of finite-type, a similar result is obtained interchanging ordinary with compactly supported differential cohomology.
Warschburger, Petra ; Calvano, Claudia ; Becker, Sebastian ; Friedt, Michael ; Hudert, Christian ; Posovszky, Carsten ; Schier, Maike ; Wegscheider, Karl
Background: Functional abdominal pain (FAP) is not only a highly prevalent disease but also poses a considerable burden on children and their families. Untreated, FAP is highly persistent until adulthood, also leading to an increased risk of psychiatric disorders. Intervention studies underscore the efficacy of cognitive behavioral treatment approaches but are limited in terms of sample size, long-term follow-up data, controls and inclusion of psychosocial outcome data.
Methods/Design: In a multicenter randomized controlled trial, 112 children aged 7 to 12 years who fulfill the Rome III criteria for FAP will be allocated to an established cognitive behavioral training program for children with FAP (n = 56) or to an active control group (focusing on age-appropriate information delivery; n = 56). Randomization occurs centrally, blockwise and is stratified by center. This study is performed in five pediatric gastroenterology outpatient departments. Observer-blind assessments of outcome variables take place four times: pre-, post-, 3- and 12-months post-treatment. Primary outcome is the course of pain intensity and frequency. Secondary endpoints are health-related quality of life, pain-related coping and cognitions, as well as selfefficacy.
Discussion: This confirmatory randomized controlled clinical trial evaluates the efficacy of a cognitive behavioral intervention for children with FAP. By applying an active control group, time and attention processes can be controlled, and long-term follow-up data over the course of one year can be explored.
We study two notions of relative differential cohomology, using the model of differential characters. The two notions arise from the two options to construct relative homology, either by cycles of a quotient complex or of a mapping cone complex. We discuss the relation of the two notions of relative differential cohomology to each other. We discuss long exact sequences for both notions, thereby clarifying their relation to absolute differential cohomology. We construct the external and internal product of relative and absolute characters and show that relative differential cohomology is a right module over the absolute differential cohomology ring. Finally we construct fiber integration and transgression for relative differential characters.
We construct new concrete examples of relative differential characters, which we call Cheeger-Chern-Simons characters. They combine the well-known Cheeger-Simons characters with Chern-Simons forms. In the same way as Cheeger-Simons characters generalize Chern-Simons invariants of oriented closed manifolds, Cheeger-Chern-Simons characters generalize Chern-Simons invariants of oriented manifolds with boundary. We study the differential cohomology of compact Lie groups G and their classifying spaces BG. We show that the even degree differential cohomology of BG canonically splits into Cheeger-Simons characters and topologically trivial characters. We discuss the transgression in principal G-bundles and in the universal bundle. We introduce two methods to lift the universal transgression to a differential cohomology valued map. They generalize the Dijkgraaf-Witten correspondence between 3-dimensional Chern-Simons theories and Wess-Zumino-Witten terms to fully extended higher-order Chern-Simons theories. Using these lifts, we also prove two versions of a differential Hopf theorem. Using Cheeger-Chern-Simons characters and transgression, we introduce the notion of differential trivializations of universal characteristic classes. It generalizes well-established notions of differential String classes to arbitrary degree. Specializing to the class , we recover isomorphism classes of geometric string structures on Spin (n) -bundles with connection and the corresponding spin structures on the free loop space. The Cheeger-Chern-Simons character associated with the class together with its transgressions to loop space and higher mapping spaces defines a Chern-Simons theory, extended down to points. Differential String classes provide trivializations of this extended Chern-Simons theory. This setting immediately generalizes to arbitrary degree: for any universal characteristic class of principal G-bundles, we have an associated Cheeger-Chern-Simons character and extended Chern-Simons theory. Differential trivialization classes yield trivializations of this extended Chern-Simons theory.
Warschburger, Petra ; Calvano, Claudia ; Becker, Sebastian ; Friedt, Michael ; Hudert, Christian ; Posovszky, Carsten ; Schier, Maike ; Wegscheider, Karl
Background: Functional abdominal pain (FAP) is not only a highly prevalent disease but also poses a considerable burden on children and their families. Untreated, FAP is highly persistent until adulthood, also leading to an increased risk of psychiatric disorders. Intervention studies underscore the efficacy of cognitive behavioral treatment approaches but are limited in terms of sample size, long-term follow-up data, controls and inclusion of psychosocial outcome data.
Methods/Design: In a multicenter randomized controlled trial, 112 children aged 7 to 12 years who fulfill the Rome III criteria for FAP will be allocated to an established cognitive behavioral training program for children with FAP (n = 56) or to an active control group (focusing on age-appropriate information delivery; n = 56). Randomization occurs centrally, blockwise and is stratified by center. This study is performed in five pediatric gastroenterology outpatient departments. Observer-blind assessments of outcome variables take place four times: pre-, post-, 3- and 12-months post-treatment. Primary outcome is the course of pain intensity and frequency. Secondary endpoints are health-related quality of life, pain-related coping and cognitions, as well as selfefficacy.
Discussion: This confirmatory randomized controlled clinical trial evaluates the efficacy of a cognitive behavioral intervention for children with FAP. By applying an active control group, time and attention processes can be controlled, and long-term follow-up data over the course of one year can be explored.
Abdalla, Hassan E. ; Aharonian, Felix A. ; Benkhali, F. Ait ; Angüner, Ekrem Oǧuzhan ; Arakawa, M. ; Arcaro, C. ; Armand, C. ; Arrieta, M. ; Backes, M. ; Barnard, M. ; Becherini, Y. ; Tjus, J. Becker ; Berge, D. ; Bernhard, S. ; Bernloehr, K. ; Blackwell, R. ; Bottcher, M. ; Boisson, C. ; Bolmont, J. ; Bonnefoy, S. ; Bordas, Pol ; Bregeon, J. ; Brun, F. ; Brun, P. ; Bryan, M. ; Buechele, M. ; Bulik, T. ; Bylund, T. ; Capasso, M. ; Caroff, S. ; Carosi, A. ; Casanova, Sabrina ; Cerruti, M. ; Chakraborty, N. ; Chandra, S. ; Chaves, R. C. G. ; Chen, A. ; Colafrancesco, S. ; Condon, B. ; Davids, I. D. ; Dei, C. ; Devin, J. ; deWilt, P. ; Dirson, L. ; Djannati-Atai, A. ; Dmytriiev, A. ; Donath, A. ; Dyks, J. ; Egberts, Kathrin ; Emery, G. ; Ernenwein, J. -P. ; Eschbach, S. ; Fegan, S. ; Fiasson, A. ; Fontaine, G. ; Funk, S. ; Füssling, Matthias ; Gabici, S. ; Gallant, Y. A. ; Garrigoux, T. ; Gate, F. ; Giavitto, G. ; Glawion, D. ; Glicenstein, J. F. ; Gottschall, D. ; Grondin, M. -H. ; Hahn, J. ; Haupt, M. ; Heinzelmann, G. ; Henri, G. ; Hermann, G. ; Hinton, J. A. ; Hofmann, W. ; Hoischen, Clemens ; Holch, T. L. ; Holler, M. ; Horns, D. ; Huber, D. ; Iwasaki, H. ; Jacholkowska, A. ; Jamrozy, M. ; Jankowsky, D. ; Jankowsky, F. ; Jouvin, L. ; Jung-Richardt, I. ; Kastendieck, M. A. ; Katarzynski, K. ; Katsuragawa, M. ; Katz, U. ; Kerszberg, D. ; Khangulyan, D. ; Khelifi, B. ; King, J. ; Klepser, S. ; Kluzniak, W. ; Komin, Nu. ; Kosack, K. ; Krakau, S. ; Kraus, M. ; Kruger, R. R. ; Lamanna, G. ; Lau, J. ; Lefaucheur, J. ; Lemiere, A. ; Lemoine-Goumard, M. ; Lenain, J. -P. ; Leser, Eva ; Lohse, T. ; Lorentz, M. ; Lopez-Coto, R. ; Lypova, I. ; Malyshev, D. ; Marandon, V. ; Marcowith, A. ; Mariaud, C. ; Marti-Devesa, G. ; Marx, R. ; Maurin, G. ; Meintjes, P. J. ; Mitche, A. M. W. ; Moderski, R. ; Mohamed, M. ; Mohrmann, L. ; Moulin, E. ; Murach, T. ; Nakashima, S. ; de Naurois, M. ; Ndiyavala, H. ; Niederwanger, F. ; Niemiec, J. ; Oakes, L. ; Odaka, H. ; Ohm, S. ; Ostrowski, M. ; Oya, I. ; Padovani, M. ; Panter, M. ; Parsons, R. D. ; Perennes, C. ; Petrucci, P. -O. ; Peyaud, B. ; Piel, Q. ; Pita, S. ; Poireau, V. ; Noel, A. Priyana ; Prokhorov, D. A. ; Prokoph, H. ; Puehlhofer, G. ; Punch, M. ; Quirrenbach, A. ; Raab, S. ; Rauth, R. ; Reimer, A. ; Reimer, O. ; Renaud, M. ; Rieger, F. ; Rinchiuso, L. ; Romoli, C. ; Rowell, G. ; Rudak, B. ; Ruiz-Velasco, E. ; Sahakian, V. ; Saito, S. ; Sanchez, David M. ; Santangelo, A. ; Sasaki, M. ; Schlickeiser, R. ; Schussler, F. ; Schulz, A. ; Schwanke, U. ; Schwemmer, S. ; Seglar-Arroyo, M. ; Senniappan, M. ; Seyffert, A. S. ; Shafi, N. ; Shilon, I. ; Shiningayamwe, K. ; Simoni, R. ; Sinha, A. ; Sol, H. ; Spanier, F. ; Specovius, A. ; Spir-Jacob, M. ; Stawarz, L. ; Steenkamp, R. ; Stegmann, Christian ; Steppa, Constantin Beverly ; Sushch, Iurii ; Takahashi, T. ; Tavernet, J. -P. ; Tavernier, T. ; Taylor, A. M. ; Terrier, R. ; Tibaldo, L. ; Tiziani, D. ; Tluczykont, M. ; Trichard, C. ; Tsirou, M. ; Tsuji, N. ; Tuffs, R. ; Uchiyama, Y. ; van der Walt, D. J. ; van Eldik, C. ; van Rensburg, C. ; van Soelen, B. ; Vasileiadis, G. ; Veh, J. ; Venter, C. ; Viana, A. ; Vincent, P. ; Vink, J. ; Voisin, F. ; Voelk, H. J. ; Vuillaume, T. ; Wadiasingh, Z. ; Wagner, S. J. ; Wagner, P. ; Wagner, R. M. ; White, R. ; Wierzcholska, A. ; Woernlein, A. ; Yang, R. ; Zaborov, D. ; Zacharias, M. ; Zanin, R. ; Zdziarski, A. A. ; Zech, Alraune ; Zefi, F. ; Ziegler, A. ; Zorn, J. ; Zywucka, N.
A hotspot at a position compatible with the BL. Lac object 1ES 2322-409 was serendipitously detected with H.E.S.S. during observations performed in 2004 and 2006 on the blazar PKS 2316-423. Additional data on 1ES 2322-409 were taken in 2011 and 2012, leading to a total live-time of 22.3 h. Point-like very-high-energy (VHE; E > 100 GeV) gamma-ray emission is detected from a source centred on the IFS 2322-409 position, with an excess of 116.7 events at a significance of 6.0 sigma. The average VHE gamma-ray spectrum is well described with a power law with a photon index Gamma = 3.40 +/- 0.66(stat) +/- 0.20(sys) and an integral flux Phi(E > 200 GeV) = (3.11 +/- 0.71(stat) 0.62(sys)) x 10(-2)cm(-2)s(-1), which corresponds to 1.1 per cent of the Crab nebula flux above 200 GeV. Multiwavelength data obtained with Fermi LAT, Swift XRT and UVOT, RXTE PCA, ATOM, and additional data from WISE, GROND, and Catalina are also used to characterize the broad-band non-thermal emission of lES 2322-409. The multiwavelength behaviour indicates day-scale variability. Swift UVOT and XRT data show strong variability at longer scales. A spectral energy distribution (SED) is built from contemporaneous observations obtained around a high state identified in Swift data. A modelling of the SED is performed with a stationary homogeneous one-zone synchrotronself-Compton leptonic model. The redshift of the source being unknown, two plausible values were tested for the modelling. A systematic scan of the model parameters space is performed, resulting in a well-constrained combination of values providing a good description of the broad-band behaviour of 1ES 2322-409.
Extended VHE gamma-ray emission towards SGR1806-20, LBV 1806-20, and stellar cluster Cl*1806-20
(2018)
Abdalla, Hassan E. ; Abramowski, A. ; Aharonian, Felix A. ; Benkhali, F. Ait ; Akhperjanian, A. G. ; Anguener, E. O. ; Arrieta, M. ; Aubert, P. ; Backes, M. ; Balzer, A. ; Barnard, M. ; Becherini, Y. ; Tjus, J. Becker ; Berge, D. ; Bernhard, S. ; Bernloehr, K. ; Birsin, E. ; Blackwell, R. ; Bottcher, M. ; Boisson, C. ; Bolmont, J. ; Bordas, Pol ; Bregeon, J. ; Brun, F. ; Brun, P. ; Bryan, M. ; Bulik, T. ; Capasso, M. ; Carr, J. ; Casanova, Sabrina ; Chakraborty, N. ; Chalme-Calvet, R. ; Chaves, R. C. G. ; Chen, A. ; Chevalier, J. ; Chretien, M. ; Colafrancesco, S. ; Cologna, G. ; Condon, B. ; Conrad, J. ; Couturier, C. ; Cui, Y. ; Davids, I. D. ; Degrange, B. ; Deil, C. ; deWilt, P. ; Djannati-Atai, A. ; Domainko, W. ; Donath, A. ; Dubus, G. ; Dutson, K. ; Dyks, J. ; Dyrda, M. ; Edwards, T. ; Egberts, Kathrin ; Eger, P. ; Ernenwein, J. -P. ; Eschbach, S. ; Farnier, C. ; Fegan, S. ; Fernandes, M. V. ; Fiasson, A. ; Fontaine, G. ; Foerster, A. ; Funk, S. ; Fuessling, M. ; Gabici, S. ; Gajdus, M. ; Gallant, Y. A. ; Garrigoux, T. ; Giavitto, G. ; Giebels, B. ; Glicenstein, J. F. ; Gottschall, D. ; Goyal, A. ; Grondin, M. -H. ; Grudzinska, M. ; Hadasch, D. ; Hahn, J. ; Hawkes, J. ; Heinzelmann, G. ; Henri, G. ; Hermann, G. ; Hervet, O. ; Hillert, A. ; Hinton, J. A. ; Hofmann, W. ; Hoischen, Clemens ; Holler, M. ; Horns, D. ; Ivascenko, A. ; Jacholkowska, A. ; Jamrozy, M. ; Janiak, M. ; Jankowsky, D. ; Jankowsky, F. ; Jingo, M. ; Jogler, T. ; Jouvin, L. ; Jung-Richardt, I. ; Kastendieck, M. A. ; Katarzynski, K. ; Katz, U. ; Kerszberg, D. ; Khelifi, B. ; Kieffer, M. ; King, J. ; Klepser, S. ; Klochkov, D. ; Kluzniak, W. ; Kolitzus, D. ; Komin, Nu. ; Kosack, K. ; Krakau, S. ; Kraus, M. ; Krayzel, F. ; Kruger, P. P. ; Laffon, H. ; Lamanna, G. ; Lau, J. ; Lees, J. -P. ; Lefaucheur, J. ; Lefranc, V. ; Lemiere, A. ; Lemoine-Goumard, M. ; Lenain, J. -P. ; Leser, E. ; Lohse, T. ; Lorentz, M. ; Liu, R. ; Lypova, I. ; Marandon, V. ; Marcowith, A. ; Mariaud, C. ; Marx, R. ; Maurin, G. ; Maxted, N. ; Mayer, M. ; Meintjes, P. J. ; Menzler, U. ; Meyer, M. ; Mitchell, A. M. W. ; Moderski, R. ; Mohamed, M. ; Mora, K. ; Moulin, E. ; Murach, T. ; de Naurois, M. ; Niederwanger, F. ; Niemiec, J. ; Oakes, L. ; Odaka, H. ; Oettl, S. ; Ohm, S. ; Ostrowski, M. ; Oya, I. ; Padovani, M. ; Panter, M. ; Parsons, R. D. ; Arribas, M. Paz ; Pekeur, N. W. ; Pelletier, G. ; Petrucci, P. -O. ; Peyaud, B. ; Pita, S. ; Poon, H. ; Prokhorov, D. ; Prokoph, H. ; Puehlhofer, G. ; Punch, M. ; Quirrenbach, A. ; Raab, S. ; Reimer, A. ; Reimer, O. ; Renaud, M. ; de los Reyes, R. ; Rieger, F. ; Romoli, C. ; Rosier-Lees, S. ; Rowell, G. ; Rudak, B. ; Rulten, C. B. ; Sahakian, V. ; Salek, D. ; Sanchez, D. A. ; Santangelo, A. ; Sasaki, M. ; Schlickeiser, R. ; Schussler, F. ; Schulz, A. ; Schwanke, U. ; Schwemmer, S. ; Seyffert, A. S. ; Shafi, N. ; Shilon, I. ; Simoni, R. ; Sol, H. ; Spanier, F. ; Spengler, G. ; Spies, F. ; Stawarz, L. ; Steenkamp, R. ; Stegmann, Christian ; Stinzing, F. ; Stycz, K. ; Sushch, I. ; Tavernet, J. -P. ; Tavernier, T. ; Taylor, A. M. ; Terrier, R. ; Tluczykont, M. ; Trichard, C. ; Tuffs, R. ; van der Walt, J. ; van Eldik, C. ; van Soelen, B. ; Vasileiadis, G. ; Veh, J. ; Venter, C. ; Viana, A. ; Vincent, P. ; Vink, J. ; Voisin, F. ; Voelk, H. J. ; Vuillaume, T. ; Wadiasingh, Z. ; Wagner, S. J. ; Wagner, P. ; Wagner, R. M. ; White, R. ; Wierzcholska, A. ; Willmann, P. ; Woernlein, A. ; Wouters, D. ; Yang, R. ; Zabalza, V. ; Zaborov, D. ; Zacharias, M. ; Zdziarski, A. A. ; Zech, Alraune ; Zefi, F. ; Ziegler, A. ; Zywucka, N.
Using the High Energy Spectroscopic System (H.E.S.S.) telescopes we have discovered a steady and extended very high-energy (VHE) gamma-ray source towards the luminous blue variable candidate LBV 1806-20, massive stellar cluster Cl* 1806-20, and magnetar SGR 1806-20. The new VHE source, HESS J1808-204, was detected at a statistical significance of >6 sigma (post-trial) with a photon flux normalisation (2.9 +/- 0.4(stat) +/- 0.5(sys)) x 10(-13) ph cm(-2) s(-1) TeV-1 at 1 TeV and a power-law photon index of 2.3 +/- 0.2(stat) +/- 0.3(sys). The luminosity of this source (0.2 to 10 TeV; scaled to distance d = 8 : 7 kpc) is L-VHE similar to 1.6 x 10(34)(d = 8.7 kpc)(2) erg s(-1). The VHE gamma-ray emission is extended and is well fit by a single Gaussian with statistical standard deviation of 0.095 degrees +/- 0.015 degrees. This extension is similar to that of the synchrotron radio nebula G10.0-0.3, which is thought to be powered by LBV 1806-20. The VHE gamma-ray luminosity could be provided by the stellar wind luminosity of LBV 1806-20 by itself and/or the massive star members of Cl* 1806-20. Alternatively, magnetic dissipation (e.g. via reconnection) from SGR 1806-20 can potentially account for the VHE luminosity. The origin and hadronic and/or leptonic nature of the accelerated particles responsible for HESS J1808-204 is not yet clear. If associated with SGR 1806 20, the potentially young age of the magnetar (650 yr) can be used to infer the transport limits of these particles to match the VHE source size. This discovery provides new interest in the potential for high-energy particle acceleration from magnetars, massive stars, and/or stellar clusters.