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- Tephrosia subtriflora (1)
- antiplasmodial (1)
- cytotoxicity (1)
- prenylated flavanonol (1)
- subtriflavanonol (1)
Aarts, Alexander A. ; Anderson, Joanna E. ; Anderson, Christopher J. ; Attridge, Peter R. ; Attwood, Angela ; Axt, Jordan ; Babel, Molly ; Bahnik, Stepan ; Baranski, Erica ; Barnett-Cowan, Michael ; Bartmess, Elizabeth ; Beer, Jennifer ; Bell, Raoul ; Bentley, Heather ; Beyan, Leah ; Binion, Grace ; Borsboom, Denny ; Bosch, Annick ; Bosco, Frank A. ; Bowman, Sara D. ; Brandt, Mark J. ; Braswell, Erin ; Brohmer, Hilmar ; Brown, Benjamin T. ; Brown, Kristina ; Bruening, Jovita ; Calhoun-Sauls, Ann ; Callahan, Shannon P. ; Chagnon, Elizabeth ; Chandler, Jesse ; Chartier, Christopher R. ; Cheung, Felix ; Christopherson, Cody D. ; Cillessen, Linda ; Clay, Russ ; Cleary, Hayley ; Cloud, Mark D. ; Cohn, Michael ; Cohoon, Johanna ; Columbus, Simon ; Cordes, Andreas ; Costantini, Giulio ; Alvarez, Leslie D. Cramblet ; Cremata, Ed ; Crusius, Jan ; DeCoster, Jamie ; DeGaetano, Michelle A. ; Della Penna, Nicolas ; den Bezemer, Bobby ; Deserno, Marie K. ; Devitt, Olivia ; Dewitte, Laura ; Dobolyi, David G. ; Dodson, Geneva T. ; Donnellan, M. Brent ; Donohue, Ryan ; Dore, Rebecca A. ; Dorrough, Angela ; Dreber, Anna ; Dugas, Michelle ; Dunn, Elizabeth W. ; Easey, Kayleigh ; Eboigbe, Sylvia ; Eggleston, Casey ; Embley, Jo ; Epskamp, Sacha ; Errington, Timothy M. ; Estel, Vivien ; Farach, Frank J. ; Feather, Jenelle ; Fedor, Anna ; Fernandez-Castilla, Belen ; Fiedler, Susann ; Field, James G. ; Fitneva, Stanka A. ; Flagan, Taru ; Forest, Amanda L. ; Forsell, Eskil ; Foster, Joshua D. ; Frank, Michael C. ; Frazier, Rebecca S. ; Fuchs, Heather ; Gable, Philip ; Galak, Jeff ; Galliani, Elisa Maria ; Gampa, Anup ; Garcia, Sara ; Gazarian, Douglas ; Gilbert, Elizabeth ; Giner-Sorolla, Roger ; Glöckner, Andreas ; Göllner, Lars ; Goh, Jin X. ; Goldberg, Rebecca ; Goodbourn, Patrick T. ; Gordon-McKeon, Shauna ; Gorges, Bryan ; Gorges, Jessie ; Goss, Justin ; Graham, Jesse ; Grange, James A. ; Gray, Jeremy ; Hartgerink, Chris ; Hartshorne, Joshua ; Hasselman, Fred ; Hayes, Timothy ; Heikensten, Emma ; Henninger, Felix ; Hodsoll, John ; Holubar, Taylor ; Hoogendoorn, Gea ; Humphries, Denise J. ; Hung, Cathy O. -Y. ; Immelman, Nathali ; Irsik, Vanessa C. ; Jahn, Georg ; Jaekel, Frank ; Jekel, Marc ; Johannesson, Magnus ; Johnson, Larissa G. ; Johnson, David J. ; Johnson, Kate M. ; Johnston, William J. ; Jonas, Kai ; Joy-Gaba, Jennifer A. ; Kappes, Heather Barry ; Kelso, Kim ; Kidwell, Mallory C. ; Kim, Seung Kyung ; Kirkhart, Matthew ; Kleinberg, Bennett ; Knezevic, Goran ; Kolorz, Franziska Maria ; Kossakowski, Jolanda J. ; Krause, Robert Wilhelm ; Krijnen, Job ; Kuhlmann, Tim ; Kunkels, Yoram K. ; Kyc, Megan M. ; Lai, Calvin K. ; Laique, Aamir ; Lakens, Daniel ; Lane, Kristin A. ; Lassetter, Bethany ; Lazarevic, Ljiljana B. ; LeBel, Etienne P. ; Lee, Key Jung ; Lee, Minha ; Lemm, Kristi ; Levitan, Carmel A. ; Lewis, Melissa ; Lin, Lin ; Lin, Stephanie ; Lippold, Matthias ; Loureiro, Darren ; Luteijn, Ilse ; Mackinnon, Sean ; Mainard, Heather N. ; Marigold, Denise C. ; Martin, Daniel P. ; Martinez, Tylar ; Masicampo, E. J. ; Matacotta, Josh ; Mathur, Maya ; May, Michael ; Mechin, Nicole ; Mehta, Pranjal ; Meixner, Johannes ; Melinger, Alissa ; Miller, Jeremy K. ; Miller, Mallorie ; Moore, Katherine ; Möschl, Marcus ; Motyl, Matt ; Müller, Stephanie M. ; Munafo, Marcus ; Neijenhuijs, Koen I. ; Nervi, Taylor ; Nicolas, Gandalf ; Nilsonne, Gustav ; Nosek, Brian A. ; Nuijten, Michele B. ; Olsson, Catherine ; Osborne, Colleen ; Ostkamp, Lutz ; Pavel, Misha ; Penton-Voak, Ian S. ; Perna, Olivia ; Pernet, Cyril ; Perugini, Marco ; Pipitone, R. Nathan ; Pitts, Michael ; Plessow, Franziska ; Prenoveau, Jason M. ; Rahal, Rima-Maria ; Ratliff, Kate A. ; Reinhard, David ; Renkewitz, Frank ; Ricker, Ashley A. ; Rigney, Anastasia ; Rivers, Andrew M. ; Roebke, Mark ; Rutchick, Abraham M. ; Ryan, Robert S. ; Sahin, Onur ; Saide, Anondah ; Sandstrom, Gillian M. ; Santos, David ; Saxe, Rebecca ; Schlegelmilch, Rene ; Schmidt, Kathleen ; Scholz, Sabine ; Seibel, Larissa ; Selterman, Dylan Faulkner ; Shaki, Samuel ; Simpson, William B. ; Sinclair, H. Colleen ; Skorinko, Jeanine L. M. ; Slowik, Agnieszka ; Snyder, Joel S. ; Soderberg, Courtney ; Sonnleitner, Carina ; Spencer, Nick ; Spies, Jeffrey R. ; Steegen, Sara ; Stieger, Stefan ; Strohminger, Nina ; Sullivan, Gavin B. ; Talhelm, Thomas ; Tapia, Megan ; te Dorsthorst, Anniek ; Thomae, Manuela ; Thomas, Sarah L. ; Tio, Pia ; Traets, Frits ; Tsang, Steve ; Tuerlinckx, Francis ; Turchan, Paul ; Valasek, Milan ; Van Aert, Robbie ; van Assen, Marcel ; van Bork, Riet ; van de Ven, Mathijs ; van den Bergh, Don ; van der Hulst, Marije ; van Dooren, Roel ; van Doorn, Johnny ; van Renswoude, Daan R. ; van Rijn, Hedderik ; Vanpaemel, Wolf ; Echeverria, Alejandro Vasquez ; Vazquez, Melissa ; Velez, Natalia ; Vermue, Marieke ; Verschoor, Mark ; Vianello, Michelangelo ; Voracek, Martin ; Vuu, Gina ; Wagenmakers, Eric-Jan ; Weerdmeester, Joanneke ; Welsh, Ashlee ; Westgate, Erin C. ; Wissink, Joeri ; Wood, Michael ; Woods, Andy ; Wright, Emily ; Wu, Sining ; Zeelenberg, Marcel ; Zuni, Kellylynn
Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.
Moving in the Anthropocene
(2018)
Tucker, Marlee A. ; Boehning-Gaese, Katrin ; Fagan, William F. ; Fryxell, John M. ; Van Moorter, Bram ; Alberts, Susan C. ; Ali, Abdullahi H. ; Allen, Andrew M. ; Attias, Nina ; Avgar, Tal ; Bartlam-Brooks, Hattie ; Bayarbaatar, Buuveibaatar ; Belant, Jerrold L. ; Bertassoni, Alessandra ; Beyer, Dean ; Bidner, Laura ; van Beest, Floris M. ; Blake, Stephen ; Blaum, Niels ; Bracis, Chloe ; Brown, Danielle ; de Bruyn, P. J. Nico ; Cagnacci, Francesca ; Calabrese, Justin M. ; Camilo-Alves, Constanca ; Chamaille-Jammes, Simon ; Chiaradia, Andre ; Davidson, Sarah C. ; Dennis, Todd ; DeStefano, Stephen ; Diefenbach, Duane ; Douglas-Hamilton, Iain ; Fennessy, Julian ; Fichtel, Claudia ; Fiedler, Wolfgang ; Fischer, Christina ; Fischhoff, Ilya ; Fleming, Christen H. ; Ford, Adam T. ; Fritz, Susanne A. ; Gehr, Benedikt ; Goheen, Jacob R. ; Gurarie, Eliezer ; Hebblewhite, Mark ; Heurich, Marco ; Hewison, A. J. Mark ; Hof, Christian ; Hurme, Edward ; Isbell, Lynne A. ; Janssen, Rene ; Jeltsch, Florian ; Kaczensky, Petra ; Kane, Adam ; Kappeler, Peter M. ; Kauffman, Matthew ; Kays, Roland ; Kimuyu, Duncan ; Koch, Flavia ; Kranstauber, Bart ; LaPoint, Scott ; Leimgruber, Peter ; Linnell, John D. C. ; Lopez-Lopez, Pascual ; Markham, A. Catherine ; Mattisson, Jenny ; Medici, Emilia Patricia ; Mellone, Ugo ; Merrill, Evelyn ; Mourao, Guilherme de Miranda ; Morato, Ronaldo G. ; Morellet, Nicolas ; Morrison, Thomas A. ; Diaz-Munoz, Samuel L. ; Mysterud, Atle ; Nandintsetseg, Dejid ; Nathan, Ran ; Niamir, Aidin ; Odden, John ; Oliveira-Santos, Luiz Gustavo R. ; Olson, Kirk A. ; Patterson, Bruce D. ; de Paula, Rogerio Cunha ; Pedrotti, Luca ; Reineking, Bjorn ; Rimmler, Martin ; Rogers, Tracey L. ; Rolandsen, Christer Moe ; Rosenberry, Christopher S. ; Rubenstein, Daniel I. ; Safi, Kamran ; Said, Sonia ; Sapir, Nir ; Sawyer, Hall ; Schmidt, Niels Martin ; Selva, Nuria ; Sergiel, Agnieszka ; Shiilegdamba, Enkhtuvshin ; Silva, Joao Paulo ; Singh, Navinder ; Solberg, Erling J. ; Spiegel, Orr ; Strand, Olav ; Sundaresan, Siva ; Ullmann, Wiebke ; Voigt, Ulrich ; Wall, Jake ; Wattles, David ; Wikelski, Martin ; Wilmers, Christopher C. ; Wilson, John W. ; Wittemyer, George ; Zieba, Filip ; Zwijacz-Kozica, Tomasz ; Mueller, Thomas
Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission.
Muiva-Mutisya, Lois M. ; Atilaw, Yoseph ; Heydenreich, Matthias ; Koch, Andreas ; Akala, Hoseah M. ; Cheruiyot, Agnes C. ; Brown, Matthew L. ; Irungu, Beatrice ; Okalebo, Faith A. ; Derese, Solomon ; Mutai, Charles ; Yenesew, Abiy
The CH2Cl2/MeOH (1:1) extract of the aerial parts of Tephrosia subtriflora afforded a new flavanonol, named subtriflavanonol (1), along with the known flavanone spinoflavanone B, and the known flavanonols MS-II (2) and mundulinol. The structures were elucidated by the use of NMR spectroscopy and mass spectrometry. The absolute configuration of the flavanonols was determined based on quantum chemical ECD calculations. In the antiplasmodial assay, compound 2 showed the highest activity against chloroquine-sensitive Plasmodiumfalciparum reference clones (D6 and 3D7), artemisinin-sensitive isolate (F32-TEM) as well as field isolate (KSM 009) with IC50 values 1.4-4.6M without significant cytotoxicity against Vero and HEp2 cell lines (IC50>100M). The new compound (1) showed weak antiplasmodial activity, IC50 12.5-24.2M, but also showed selective anticancer activity against HEp2 cell line (CC50 16.9M). [GRAPHICS] .
Armstrong, Michael R. ; Radousky, Harry B. ; Austin, Ryan A. ; Tschauner, Oliver ; Brown, Shaughnessy ; Gleason, Arianna E. ; Goldman, Nir ; Granados, Eduardo ; Grivickas, Paulius ; Holtgrewe, Nicholas ; Kroonblawd, Matthew P. ; Lee, Hae Ja ; Lobanov, Sergey S. ; Nagler, Bob ; Nam, Inhyuk ; Prakapenka, Vitali ; Prescher, Clemens ; Reed, Evan J. ; Stavrou, Elissaios ; Walter, Peter ; Goncharov, Alexander F. ; Belof, Jonathan L.
The response of rapidly compressed highly oriented pyrolytic graphite (HOPG) normal to its basal plane was investigated at a pressure of & SIM;80 GPa. Ultrafast x-ray diffraction using & SIM;100 fs pulses at the Materials Under Extreme Conditions sector of the Linac Coherent Light Source was used to probe the changes in crystal structure resulting from picosecond timescale compression at laser drive energies ranging from 2.5 to 250 mJ. A phase transformation from HOPG to a highly textured hexagonal diamond structure is observed at the highest energy, followed by relaxation to a still highly oriented, but distorted graphite structure following release. We observe the formation of a highly oriented lonsdaleite within 20 ps, subsequent to compression. This suggests that a diffusionless martensitic mechanism may play a fundamental role in phase transition, as speculated in an early work on this system, and more recent static studies of diamonds formed in impact events. Published by AIP Publishing.
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