Refine
Year of publication
Document Type
Is part of the Bibliography
- yes (179)
Keywords
- biomaterials (8)
- Polymer (6)
- polymer (6)
- shape-memory effect (6)
- biomaterial (5)
- stimuli-sensitive polymers (5)
- Biomaterial (4)
- Langmuir monolayer (4)
- mesenchymal stem cells (4)
- shape memory (4)
- Degradation (3)
- Hydrogel (3)
- artificial muscles (3)
- cell adhesion (3)
- endothelial cells (3)
- hemocompatibility (3)
- microparticles (3)
- morphology (3)
- multiblock copolymer (3)
- soft robotics (3)
- Actuation (2)
- Biomaterials (2)
- Biomimetic (2)
- Biopolymer (2)
- Degradable (2)
- Depsipeptide (2)
- HDAC1 (2)
- Hyaluronic acid (2)
- Membrane (2)
- Molecular modeling (2)
- Nanostructure (2)
- Oligo(epsilon-caprolactone) (2)
- Phase morphology (2)
- Poly(epsilon-caprolactone) (2)
- Polymers (2)
- RUNX2 (2)
- Rheology (2)
- Shape memory (2)
- Shape-memory effect (2)
- Shape-memory polymer (2)
- Temperature-memory effect (2)
- Thin film (2)
- actuation (2)
- atomic force microscopy (2)
- biodegradable polymers (2)
- calcium influx (2)
- crystallization (2)
- crystallization behavior (2)
- degradation (2)
- electrospinning (2)
- ellipsometry (2)
- fiber actuators (2)
- hydrogels (2)
- mechanical (2)
- oligodepsipeptides (2)
- phase morphology (2)
- platelets (2)
- poly(epsilon-caprolactone) (2)
- poly(ethylene glycol) (2)
- polyester (2)
- polyesterurethanes (2)
- properties (2)
- resistive heating (2)
- reversible shape-memory actuator (2)
- ring-opening polymerization (2)
- shape-memory polymers (2)
- shape‐memory polymer actuators (2)
- soft actuators (2)
- spectroscopic ellipsometry (2)
- surface functionalization (2)
- thrombogenicity (2)
- (NMR) (1)
- 2D materials (1)
- 3D-printing (1)
- 4D-actuation (1)
- Actuators (1)
- Additive manufacturing (1)
- Adipocyte (1)
- Adsorption of uremic toxins (1)
- Aerophobicity (1)
- Ageing (1)
- Air bubble repellence (1)
- Angle-dependent X-ray induced photoelectron spectroscopy (1)
- Antiviral (1)
- Biocompatible polymers (1)
- Biomolecules coupling (1)
- Biopolymer material (1)
- Biopolymers (1)
- Brewster angle microscopy (1)
- COVID-19 (1)
- Cartilage repair (1)
- Chronic kidney disease (1)
- Chronic kidney disease (CKD) (1)
- Cinnamylidene acetic acid (1)
- Click chemistry (1)
- Collagen-binding peptide (1)
- Crosslinking (1)
- Deformation (1)
- Docking study (1)
- Drug loading (1)
- Electrospinning (1)
- Energy (1)
- Energy storage (1)
- Enzymatic degradation (1)
- Enzymatic polymer degradation (1)
- Fastener (1)
- Fiber (1)
- Function by design (1)
- Functionalization (1)
- Gelatin (1)
- Gripper (1)
- High-throughput (1)
- Hydrogels (1)
- Hydrolytic degradation (1)
- Hydrolytic stability (1)
- Hypoxia (1)
- In situ (1)
- Inflammation (1)
- Ink (1)
- Ki67 (1)
- Langmuir layers (1)
- Langmuir monolayer degradation technique (1)
- Langmuir monolayers (1)
- Langmuir technique (1)
- Langmuir thin-films (1)
- Langmuir-Schafer films (1)
- Macrophage (1)
- Magnetic composites (1)
- Magnetite nanoparticles (1)
- Mass spectrometry (1)
- Matrix metalloproteinase (1)
- Mechanical properties (1)
- Methacrylate (1)
- Microindentation (1)
- Microstructure (1)
- Modeling (1)
- Modelling (1)
- Molecular (1)
- Molecular dynamics simulation (1)
- Molecular interaction design (1)
- Molecular orientation (1)
- Molecular weight (1)
- Morpholindione (1)
- Multiblock copolymer (1)
- Multiblock copolymers (1)
- Multifunctional polyester networks (1)
- Multifunctionality (1)
- NICE-2014 (1)
- Nanofiber (1)
- Nanoparticles (1)
- Near infrared light triggered shape-recovery (1)
- Negative control (1)
- Nuclear magnetic resonance (1)
- Oligo(ethylene glycol) (1)
- Oligo(omega-pentadecalactone) (1)
- Oligodepsipeptide (1)
- Oligoglycerols (1)
- On-demand release (1)
- PDLLGA (1)
- PHA-depolymerases (1)
- Packaging (1)
- Particle shape (1)
- Particle size (1)
- Phagocytosis (1)
- Photoresponsive polymers (1)
- Physical Network (1)
- Platelet (1)
- Poly(carbonate-urea-urethane)s (1)
- Poly(epsilon-caprolactone) networks (1)
- Poly(ether imide) (1)
- Poly(n-butyl acrylate) (1)
- Polyesterurethane (1)
- Polyether ether ketone (1)
- Polylactide stereocomplex (1)
- Polymer architecture (1)
- Polymer functionalization (1)
- Polymer micronetwork colloids (1)
- Polymer network properties (1)
- Polymer networks (1)
- Polymeric substrate (1)
- Porous poly(ether imide) microparticulate absorbers (1)
- Protein (1)
- Proteins (1)
- RGD peptides (1)
- RGD-peptide (1)
- Raman spectroscopy (1)
- Random copolymer (1)
- Ring-opening polymerization (1)
- Robotic synthesis (1)
- Robotics (1)
- SAXS (1)
- Scaffold contraction (1)
- Scaffold degradation (1)
- Scaffold stiffness (1)
- Scanning probe microscopy (SPM) (1)
- Sequence structure (1)
- Shape-memory (1)
- Simulation (1)
- Sn(IV) alkoxide (1)
- Submicron particles (1)
- Sulfated polymer (1)
- Surface functionalization (1)
- Surface reaction (1)
- Surfactants (1)
- Switchable wettability (1)
- TCP (1)
- THP-1 cells (1)
- Telechel (1)
- Thermo-responsive polymer (1)
- Thermomechanical history (1)
- Tin octanoate (1)
- Uremic toxins (1)
- VEGF (1)
- WAXS (1)
- Water (1)
- X-ray scattering (1)
- actin cytoskeleton (1)
- active polymer (1)
- active scaffold (1)
- air - water interface (1)
- amide ligand (1)
- amorphous polymers (1)
- assembly capabilities (1)
- atomic force microscopy (AFM) (1)
- basement membrane (1)
- beta-galactosidase (1)
- biocompatibility (1)
- biofunctionalization (1)
- bioinspired materials (1)
- bioinstructive implants (1)
- bioinstructive materials (1)
- biological applications of polymers (1)
- biological membrane (1)
- biomaterial-tissue interface (1)
- biomedical (1)
- biomimetic (chemical reaction) (1)
- biopolymer (1)
- bioprinting (1)
- blend (1)
- block copolymers (1)
- block-copolymer (1)
- blood tests (1)
- body temperature (1)
- brewster angle microscopy (1)
- broad melting temperature range (1)
- cardiac regeneration (1)
- cardiovascular disease (1)
- cardiovascular implant (1)
- catalyst (1)
- cavitation-based mechanical force (1)
- cell culture device (1)
- cell cycle inhibitors (1)
- cell-material interaction (1)
- chain-extended (1)
- chemical synthesis (1)
- chronic kidney disease (CKD) (1)
- cold (1)
- collagen (1)
- collagen-IV (1)
- composite (1)
- controlled release (1)
- controlled-release (1)
- coordination bonds (1)
- copolymer networks (1)
- copper-catalyzed alkyne-azide cycloaddition (1)
- critical micellation temperature (1)
- cross-linking (1)
- crosslinking (1)
- crystal structures (1)
- crystalline (1)
- crystallinity (1)
- cyclic olefin copolymer (1)
- cyclic thermomechanical testing (1)
- cyclodextrin (1)
- cytotoxicity (1)
- dedifferentiation (1)
- degradable (1)
- degradable polyester (1)
- dendritic cells (1)
- elastomers (1)
- electron microscopy (1)
- ellipsometric mapping (1)
- endothelial basement membrane (1)
- engineering (1)
- enzymatic degradation (1)
- enzymatic-degradation (1)
- enzyme (1)
- ethylene oxide (1)
- excimer UV light (1)
- extracellular matrix modifying enzymes (1)
- fiber meshes (1)
- fibers (1)
- fibrinogen (1)
- fibroblast (1)
- films (1)
- fluorescence stimuli‐ responsivity (1)
- foam (1)
- focal adhesion (1)
- form stability (1)
- function (1)
- function by structure; (1)
- functional (1)
- functionalization of polymers (1)
- gelatin (1)
- gelatin-based hydrogels (1)
- gels (1)
- glass (1)
- hemodialysis (1)
- human monocytic (THP-1) cells (1)
- hydrogel (1)
- hydrophobic uremic toxins (1)
- implants (1)
- in vitro (1)
- in vitro thrombogenicity testing (1)
- inclusion complex (1)
- induced pluripotent stem cells (1)
- inverse (1)
- iron (1)
- langmuir monolayer (1)
- libraries (1)
- library (1)
- life cycle assessment (1)
- lipase release (1)
- lipases (1)
- lipid (1)
- liquid-crystalline polymers (1)
- magnetic (1)
- magnetic nanoparticles (1)
- magnetosensitivity (1)
- materials science (1)
- mechanical property (1)
- microgels (1)
- microporous (1)
- microscale (1)
- microstructure (1)
- modulation of in vivo regeneration (1)
- modulus (1)
- molecular dynamics simulations (1)
- molecular modeling (1)
- multiblock copolymers (1)
- multifunctional biomaterials (1)
- multifunctional polymers (1)
- multiple functions (1)
- nanocarriers (1)
- nanocomposites (1)
- nanoparticle characterization (1)
- nanoscale (1)
- nanostructure (1)
- networks (1)
- on demand particle release (1)
- optical imaging (1)
- orientational memory (1)
- osteogenic differentiation (1)
- oxygen plasma (1)
- p16 (1)
- p21 (1)
- particulate (1)
- peptides (1)
- photoinduced radical polymerization (1)
- platelet activation (1)
- platelet adhesion (1)
- platelet aging (1)
- platelet function (1)
- platelet rich plasma (1)
- platelet storage (1)
- platelet-rich plasma (1)
- poly(e-caprolactone) (1)
- poly(epsilon-caprolactone) methacrylate (1)
- poly(ester amide)s (1)
- poly(ether imide) (1)
- poly(ether imide) microparticles (1)
- poly(n-butyl acrylate) (1)
- poly(tetrafluoroethylene) (1)
- poly[(rac-lactide)-co-glycolide] (1)
- polyamines (1)
- polycaprolactone (1)
- polydepsipeptide (1)
- polyesters (1)
- polyesterurethane (1)
- polyglycerol (1)
- polyhydroxyalkanoates (PHA) (1)
- polyimides (1)
- polymer actuators (1)
- polymer surface (1)
- polymers (1)
- polysiloxanes (1)
- population doubling time (1)
- porosity (1)
- processing (1)
- protein (1)
- protein Langmuir layers (1)
- protein adsorption (1)
- protein-protein interactions (1)
- reactive oxygen species (ROS) (1)
- reference (1)
- renewable (1)
- reshaping abilities (1)
- responsive (1)
- reversible bidirectional shape-memory polymer (1)
- reversible shape-memory effect (1)
- rheology (1)
- rhodium(I)– phosphine (1)
- rhodium-phosphine coordination bonds (1)
- ring opening polymerization (1)
- root mean square roughness (1)
- self-healing (1)
- semi-IPN hydrogels (1)
- semi-crystalline (1)
- senescence-associated (1)
- sequence structures (1)
- shape (1)
- shape change (1)
- shape shifting materials (1)
- shape-memory (1)
- shape-memory hydrogel (1)
- shape-memory polymer (1)
- shape-memory polymer actuators (1)
- shape-memory properties (1)
- side reaction (1)
- side-chains functionalization (1)
- soft matter micro- and nanowires (1)
- solvent resistance (1)
- stem cell adhesion (1)
- stereocomplexes (1)
- sterilization (1)
- stimuli-sensitive materials (1)
- sulfation (1)
- supramolecular polymer network (1)
- surface chemistry (1)
- surface coating (1)
- surfaces (1)
- sustainability (1)
- switch (1)
- telechelics (1)
- temperature (1)
- temperature-memory effect (1)
- temperature-memory polymers (1)
- thermal properties (1)
- thermal treatments (1)
- thermo-sensitivity (1)
- thermomechanical properties (1)
- thermoplastic elastomer (1)
- thermoplastics (1)
- thermoresponsive polymers (1)
- thermosensitive (1)
- thrombocyte adhesion (1)
- tin(II) 2-ethylhexanoate (1)
- tissue (1)
- triple-shape effect (1)
- two dimensional network (1)
- ultrasound (1)
- uremia (1)
- vascular graft (1)
- vascular grafts (1)
- viability (1)
- whole blood (1)
- wide angle x‐ ray scattering (1)
Institute
- Institut für Chemie (179) (remove)
Within the natural world, organisms use information stored in their material structure to generate a physical response to a wide variety of environmental changes. The ability to program synthetic materials to intrinsically respond to environmental changes in a similar manner has the potential to revolutionize material science. By designing polymeric devices capable of responsively changing shape or behavior based on information encoded into their structure, we can create functional physical behavior, including a shape memory and an actuation capability. Here we highlight the stimuli-responsiveness and shape-changing ability of biological materials and biopolymer-based materials, plus their potential biomedical application, providing a bioperspective on shape-memory materials. We address strategies to incorporate a shape memory (actuation) function in polymeric materials, conceptualized in terms of its relationship with inputs (environmental stimuli) and outputs (shape change). Challenges and opportunities associated with the integration of several functions in a single material body to achieve multifunctionality are discussed. Finally, we describe how elements that sense, convert, and transmit stimuli have been used to create multisensitive materials.
Ethylene oxide sterilization of electrospun poly(L-lactide)/poly(D-lactide) core/shell nanofibers
(2021)
The application of polymers in medicine requires sterilization while retaining material structure and properties. This demands detailed analysis, which we show exemplarily for the sterilization of PLLA/PDLA core-shell nanofibers with ethylene oxide (EtO). The electrospun patch was exposed to EtO gas (6 vol% in CO2, 1.7 bar) for 3 h at 45 degrees C and 75% rel. humidity, followed by degassing under pressure/vacuum cycles for 12 h. GC-MS analysis showed that no residual EtO was retained. Fiber diameters (similar to 520 +/- 130 nm) of the patches remained constant as observed by electron microscopy. Young's modulus slightly increased and the elongation at break slightly decreased, determined at 37 degrees C. No changes were detected in H-1-NMR spectra, in molar mass distribution (GPC) or in crystallinity measured for annealed samples with comparable thermal history (Wide Angle X-Ray Scattering). Altogether, EtO emerged as suitable sterilization method for polylactide nanofibers with core-shell morphology.
Using standard cell biological and biochemical methods we were able to test the ability of a degradable, thermoplastic block copolymer to support the adhesion, proliferation, and the cellular activity of primary cell cultures of the oral cavity in vitro. The delicate balance between a group of endogenous enzymes, Matrix Metalloproteinases (MMPs), and their inhibitors (Tissue Inhibitor of MMPs, TIMPs) have a decisive function in the remodeling of the extracellular matrix during processes like wound healing or the integration of biomaterials in surrounding tissues after implantation. Recently developed, biodegradable thermoplastic elastomers with shape-memory properties may be the key to develop new therapeutical options in head and neck surgery. Primary cell cultures of the oral cavity of Sprague-Dawley rats were seeded on the surface of a thermoplastic block copolymer and on a polystyrene surface as control. Conditioned media of the primary cells were analyzed for MMPs and TIMPs after different periods of cell growth. The MMP and TIMP expression was analysed by zymography and a radiometric enzyme assay. No statistically significant differences in the appearance and the kinetic of MMP-1, MMP-2, MMP-9 and TIMPs were detected between cells grown on the polymer surface compared to the control. An appropriate understanding of the molecular processes that regulate cellular growth and integration of a biomaterial in surrounding tissue is the requirement for an optimal adaptation of biodegradable, polymeric biomaterials to the physiological, anatomical, and surgical conditions in vivo to develop new therapeutic options in otolaryngology and head and neck surgery
Shape-memory polymers
(2004)