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The current trends of crop yield improvements are not expected to meet the projected rise in demand. Genomic selection uses molecular markers and machine learning to identify superior genotypes with improved traits, such as growth. Plant growth directly depends on rates of metabolic reactions which transform nutrients into the building blocks of biomass. Here, we predict growth of Arabidopsis thaliana accessions by employing genomic prediction of reaction rates estimated from accession-specific metabolic models. We demonstrate that, comparing to classical genomic selection on the available data sets for 67 accessions, our approach improves the prediction accuracy for growth within and across nitrogen environments by 32.6% and 51.4%, respectively, and from optimal nitrogen to low carbon environment by 50.4%. Therefore, integration of molecular markers into metabolic models offers an approach to predict traits directly related to metabolism, and its usefulness in breeding can be examined by gathering matching datasets in crops. An increase in genomic selection (GS) accuracy can accelerate genetic gain by shortening the breeding cycles. Here, the authors introduce a network-based GS method that uses metabolic models and improves the prediction accuracy of Arabidopsis growth within and across environments.
Flood risk assessments are typically based on scenarios which assume homogeneous return periods of flood peaks throughout the catchment. This assumption is unrealistic for real flood events and may bias risk estimates for specific return periods. We investigate how three assumptions about the spatial dependence affect risk estimates: (i) spatially homogeneous scenarios (complete dependence), (ii) spatially heterogeneous scenarios (modelled dependence) and (iii) spatially heterogeneous but uncorrelated scenarios (complete independence). To this end, the model chain RFM (regional flood model) is applied to the Elbe catchment in Germany, accounting for the spatio-temporal dynamics of all flood generation processes, from the rainfall through catchment and river system processes to damage mechanisms. Different assumptions about the spatial dependence do not influence the expected annual damage (EAD); however, they bias the risk curve, i.e. the cumulative distribution function of damage. The widespread assumption of complete dependence strongly overestimates flood damage of the order of 100% for return periods larger than approximately 200 years. On the other hand, for small and medium floods with return periods smaller than approximately 50 years, damage is underestimated. The overestimation aggravates when risk is estimated for larger areas. This study demonstrates the importance of representing the spatial dependence of flood peaks and damage for risk assessments.
We study properties of magnetohydrodynamic (MHD) eigenmodes by decomposing the data of MHD simulations into linear MHD modes-namely, the Alfven, slow magnetosonic, and fast magnetosonic modes. We drive turbulence with a mixture of solenoidal and compressive driving while varying the Alfven Mach number (M-A), plasma beta, and the sonic Mach number from subsonic to transsonic. We find that the proportion of fast and slow modes in the mode mixture increases with increasing compressive forcing. This proportion of the magnetosonic modes can also become the dominant fraction in the mode mixture. The anisotropy of the modes is analyzed by means of their structure functions. The Alfven-mode anisotropy is consistent with the Goldreich-Sridhar theory. We find a transition from weak to strong Alfvenic turbulence as we go from low to high M-A. The slow-mode properties are similar to the Alfven mode. On the other hand, the isotropic nature of fast modes is verified in the cases where the fast mode is a significant fraction of the mode mixture. The fast-mode behavior does not show any transition in going from low to high M-A. We find indications that there is some interaction between the different modes, and the properties of the dominant mode can affect the properties of the weaker modes. This work identifies the conditions under which magnetosonic modes can be a major fraction of turbulent astrophysical plasmas, including the regime of weak turbulence. Important astrophysical implications for cosmic-ray transport and magnetic reconnection are discussed.
Der brandenburgische Landtag beschloss im Dezember 2019 kurz vor Beginn der uneingeschränkten Geltung der grundgesetzlichen Schuldenbremse für die Länder ab dem 01.01.2020 mit den Stimmen der neuen Regierungskoalition aus SPD, CDU und BÜNDNIS 90/DIE GRÜNEN die Errichtung eines vollständig kreditfinanzierten Sondervermögens »Zukunftsinvestitionsfonds des Landes Brandenburg«, dessen Mittel in Höhe von einer Mrd. Euro in den kommenden Jahren zur Verbesserung der Infrastruktur eingesetzt werden sollen (I.). Dies wirft die Frage auf, ob die verfassungsrechtlichen Haushaltsgrundsätze der stetigen Aufgabenerfüllung (II.), der Einheit und Vollständigkeit des Haushalts (III.), der Haushaltsklarheit und Haushaltsöffentlichkeit (IV.), der Sparsamkeit und Wirtschaftlichkeit (V.), des Jährlichkeitsprinzips (VI.) und nicht zuletzt des Haushaltsausgleichs (VII.) gewahrt worden sind. Letztlich steht das Budgetrecht des Parlaments selbst in Frage (VIII.). Hinzu treten etwaige europarechtliche Verwerfungen (IX.). Nach einer Darstellung der prozessualen Möglichkeiten, gegen dieses Sondervermögen vorzugehen (X.), rundet eine Zusammenfassung die Darstellung ab (XI.).
In recent years, nature-based solutions are receiving increasing attention in the field of disaster risk reduction and climate change adaptation as inclusive, no regret approaches. Ecosystem-based adaptation (EbA) can mitigate the impacts of climate change, build resilience and tackle environmental degradation thereby supporting the targets set by the 2030 Agenda, the Paris Agreement and the Sendai Framework. Despite these benefits, EbA is still rarely implemented in practice. To better understand the barriers to implementation, this research examines policy-makers' perceptions of EbA, using an extended version of Protection Motivation Theory as an analytical framework. Through semi-structured interviews with policy-makers at regional and provincial level in Central Vietnam, it was found that EbA is generally considered a promising response option, mainly due to its multiple ecosystem-service benefits. The demand for EbA measures was largely driven by the perceived consequences of natural hazards and climate change. Insufficient perceived response efficacy and time-lags in effectiveness for disaster risk reduction were identified as key impediments for implementation. Pilot projects and capacity building on EbA are important means to overcome these perceptual barriers. This paper contributes to bridging the knowledge-gap on political decision-making regarding EbA and can, thereby, promote its mainstreaming into policy plans.
Context:
Gyrochronology allows the derivation of ages for cool main sequence stars based on their observed rotation periods and masses, or a suitable proxy thereof. It is increasingly well-explored for FGK stars, but requires further measurements for older ages and K - M-type stars.
Aims:
We study the 2.7 Gyr-old open cluster Ruprecht 147 to compare it with the previously-studied, but far more distant, NGC 6819 cluster, and especially to measure cooler stars than was previously possible there.
Methods:
We constructed an inclusive list of 102 cluster members from prior work, including Gaia DR2, and for which light curves were also obtained during Campaign 7 of the Kepler/K2 space mission. We placed them in the cluster color-magnitude diagram and checked the related information against appropriate isochrones. The light curves were then corrected for data systematics using Principal Component Analysis on all observed K2 C07 stars and subsequently subjected to periodicity analysis.
Results:
Periodic signals are found for 32 stars, 21 of which are considered to be both highly reliable and to represent single, or effectively single, Ru 147 stars. These stars cover the spectral types from late-F to mid-M stars, and they have periods ranging from 6 d - 33 d, allowing for a comparison of Ruprecht 147 to both other open clusters and to models of rotational spindown. The derived rotation periods connect reasonably to, overlap with, and extend to lower masses the known rotation period distribution of the 2.5 Gyr-old cluster NGC 6819.
Conclusions:
The data confirm that cool stars lie on a single surface in rotation period-mass-age space, and they simultaneously challenge its commonly assumed shape. The shape at the low mass region of the color-period diagram at the age of Ru 147 favors a recently-proposed model which requires a third mass-dependent timescale in addition to the two timescales required by a former model, suggesting that a third physical process is required to model rotating stars effectively.
Controversy over the plate tectonic affinity and evolution of the Saxon granulites in a two- or multi-plate setting during inter- or intracontinental collision makes the Saxon Granulite Massif a key area for the understanding of the Palaeozoic Variscan orogeny. The massif is a large dome structure in which tectonic slivers of metapelite and metaophiolite units occur along a shear zone separating a diapir-like body of high-Pgranulite below from low-Pmetasedimentary rocks above. Each of the upper structural units records a different metamorphic evolution until its assembly with the exhuming granulite body. New age and petrologic data suggest that the metaophiolites developed from early Cambrian protoliths during high-Pamphibolite facies metamorphism in the mid- to late-Devonian and thermal overprinting by the exhuming hot granulite body in the early Carboniferous. A correlation of new Ar-Ar biotite ages with publishedP-T-tdata for the granulites implies that exhumation and cooling of the granulite body occurred at average rates of similar to 8 mm/year and similar to 80 degrees C/Ma, with a drop in exhumation rate from similar to 20 to similar to 2.5 mm/year and a slight rise in cooling rate between early and late stages of exhumation. A time lag ofc. 2 Ma between cooling through the closure temperatures for argon diffusion in hornblende and biotite indicates a cooling rate of 90 degrees C/Ma when all units had assembled into the massif. A two-plate model of the Variscan orogeny in which the above evolution is related to a short-lived intra-Gondwana subduction zone conflicts with the oceanic affinity of the metaophiolites and the timescale ofc. 50 Ma for the metamorphism. Alternative models focusing on the internal Variscan belt assume distinctly different material paths through the lower or upper crust for strikingly similar granulite massifs. An earlier proposed model of bilateral subduction below the internal Variscan belt may solve this problem.
"Left" and "right" coordinates control our spatial behavior and even influence abstract thoughts. For number concepts, horizontal spatial-numerical associations (SNAs) have been widely documented: we associate few with left and many with right. Importantly, increments are universally coded on the right side even in preverbal humans and nonhuman animals, thus questioning the fundamental role of directional cultural habits, such as reading or finger counting. Here, we propose a biological, nonnumerical mechanism for the origin of SNAs on the basis of asymmetric tuning of animal brains for different spatial frequencies (SFs). The resulting selective visual processing predicts both universal SNAs and their context-dependence. We support our proposal by analyzing the stimuli used to document SNAs in newborns for their SF content. As predicted, the SFs contained in visual patterns with few versus many elements preferentially engage right versus left brain hemispheres, respectively, thus predicting left-versus rightward behavioral biases. Our "brain's asymmetric frequency tuning" hypothesis explains the perceptual origin of horizontal SNAs for nonsymbolic visual numerosities and might be extensible to the auditory domain.
A silica undersaturated alkali-olivine basanitic magma intruded the late Paleocene/early Eocene Jafnayn Formation near Muscat. Geochemical analyses indicate that a significant amount of host rock (limestone) was assimilated into the magma. We dated the basanite as 42.7 +/- 1.0 Ma (2 sigma error; late Lutetian), using the whole rock Ar-40/Ar-39 step-wise heating technique. Intrusion occurred in the hanging wall of a major regional extensional shear zone (Frontal Range Fault, FRF) bounding the northern margin of two domes within the Oman Mountains (Jabal Akhdar and Saih Hatat domes). Two shear intervals along the FRF have been documented. The first interval lasted immediately after emplacement of the Semail Ophiolite (latest Cretaceous-early Eocene) while the second and poorly constrained interval was assumed to have occurred during the Oligocene.
The proximity of the basanite to the FRF suggests that magma used extensional faults for the upper part of its ascent path. Reactivated Permian rift faults of the Pangaea rift or other preexisting faults may have been used for the lower ascent part.
We conclude that the basanite intrusion coincided with the onset of the second deformation interval along the FRF, because (1) the position of the basanite is near a dextral releasing bend, associated with the second shear interval, (2) the overlap of our Ar-40/Ar-39 age with the cooling curves for rocks from the nearby Jabal Akhdar Dome, and (3) the basanite postdates the first FRF deformation episode by > 10 Ma. Thus, the second interval along the FRF had started already during the late Lutetian and probably lasted into the Miocene.
Recent research has linked sphingolipid (SL) metabolism with cystic fibrosis transmembrane conductance regulator (CFTR) activity, affecting bioactive lipid mediator sphingosine-1-phosphate (S1P). We hypothesize that loss of CFTR function in cystic fibrosis (CF) patients influenced plasma S1P levels. Total and unbound plasma S1P levels were measured in 20 lung-transplanted adult CF patients and 20 healthy controls by mass spectrometry and enzyme-linked immunosorbent assay (ELISA). S1P levels were correlated with CFTR genotype, routine laboratory parameters, lung function and pathogen colonization, and clinical symptoms. Compared to controls, CF patients showed lower unbound plasma S1P, whereas total S1P levels did not differ. A positive correlation of total and unbound S1P levels was found in healthy controls, but not in CF patients. Higher unbound S1P levels were measured in Delta F508-homozygous compared to Delta F508-heterozygous CF patients (p = 0.038), accompanied by higher levels of HDL in Delta F508-heterozygous patients. Gastrointestinal symptoms were more common in Delta F508 heterozygotes compared to Delta F508 homozygotes. This is the first clinical study linking plasma S1P levels with CFTR function and clinical presentation in adult CF patients. Given the emerging role of immunonutrition in CF, our study might pave the way for using S1P as a novel biomarker and nutritional target in CF.