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We report on very high energy (>100 GeV) gamma-ray observations of Swift J164449.3+573451, an unusual transient object first detected by the Swift Observatory and later detected by multiple radio, optical, and X-ray observatories. A total exposure of 28 hr was obtained on Swift J164449.3+573451 with the Very Energetic Radiation Imaging Telescope Array System ( VERITAS) during 2011 March 28-April 15. We do not detect the source and place a differential upper limit on the emission at 500 GeV during these observations of 1.4 x 10(-12) erg cm(-2) s(-1) (99% confidence level). We also present time-resolved upper limits and use a flux limit averaged over the X-ray flaring period to constrain various emission scenarios that can accommodate both the radio-through-X-ray emission detected from the source and the lack of detection by VERITAS.
Business processes are commonly modeled using a graphical modeling language. The most widespread notation for this purpose is business process diagrams in the Business Process Modeling Notation (BPMN). In this article, we use the visual query language BPMN-Q for expressing patterns that are related to possible problems in such business process diagrams. We discuss two classes of problems that can be found frequently in real-world models: sequence flow errors and model fragments that can make the model difficult to understand.
By using a query processor, a business process modeler is able to identify possible errors in business process diagrams. Moreover, the erroneous parts of the business process diagram can be highlighted when an instance of an error pattern is found. This way, the modeler gets an easy-to-understand feedback in the visual modeling language he or she is familiar with. This is an advantage over current validation methods, which usually lack this kind of intuitive feedback.
Miniature eye movements jitter the retinal image unceasingly, raising the question of how perceptual continuity is achieved during visual fixation. Recent work discovered suppression of visual bursts in the superior colliculus around the time of microsaccades, tiny jerks of the eyes that support visual perception while gaze is fixed. This finding suggests that corollary discharge, supporting visual stability when rapid eye movements drastically shift the retinal image, may also exist for the smallest saccades.
A business process is a set of steps designed to be executed in a certain order to achieve a business value. Such processes are often driven by and documented using process models. Nowadays, process models are also applied to drive process execution. Thus, correctness of business process models is a must. Much of the work has been devoted to check general, domain-independent correctness criteria, such as soundness. However, business processes must also adhere to and show compliance with various regulations and constraints, the so-called compliance requirements. These are domain-dependent requirements.
In many situations, verifying compliance on a model level is of great value, since violations can be resolved in an early stage prior to execution. However, this calls for using formal verification techniques, e.g., model checking, that are too complex for business experts to apply. In this paper, we utilize a visual language. BPMN-Q to express compliance requirements visually in a way similar to that used by business experts to build process models. Still, using a pattern based approach, each BPMN-Qgraph has a formal temporal logic expression in computational tree logic (CTL). Moreover, the user is able to express constraints, i.e., compliance rules, regarding control flow and data flow aspects. In order to provide valuable feedback to a user in case of violations, we depend on temporal logic querying approaches as well as BPMN-Q to visually highlight paths in a process model whose execution causes violations.
Vitamin A metabolism is changed in donors after living-kidney transplantation an observational study
(2011)
Background: The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin. Little is known about changes in serum concentration after living donor kidney transplantation (LDKT) as a consequence of unilateral nephrectomy; although an association of these parameters with the risk of cardiovascular diseases and insulin resistance has been suggested. Therefore we analyzed the concentration of retinol, RBP4, apoRBP4 and transthyretin in serum of 20 living-kidney donors and respective recipients at baseline as well as 6 weeks and 6 months after LDKT.
Results: As a consequence of LDKT, the kidney function of recipients was improved while the kidney function of donors was moderately reduced within 6 weeks after LDKT. With regard to vitamin A metabolism, the recipients revealed higher levels of retinol, RBP4, transthyretin and apoRBP4 before LDKT in comparison to donors. After LDKT, the levels of all four parameters decreased in serum of the recipients, while retinol, RBP4 as well as apoRBP4 serum levels of donors increased and remained increased during the follow-up period of 6 months.
Conclusion: LDKT is generally regarded as beneficial for allograft recipients and not particularly detrimental for the donors. However, it could be demonstrated in this study that a moderate reduction of kidney function by unilateral nephrectomy, resulted in an imbalance of components of vitamin A metabolism with a significant increase of retinol and RBP4 and apoRBP4 concentration in serum of donors.
This Letter reports on new methods and a consistent model for voltage tunable optical transmission gratings. Elastomeric gratings were molded from holographically written surface relief gratings in an azobenzene sol-gel material. These were placed on top of a transparent electroactive elastomeric substrate. Two different electro-active substrate elastomers were employed, with a large range of prestretches. A novel finite-deformation theory was found to match the device response excellently, without fitting parameters. The results clearly show that the grating underwent pure-shear deformation, and more surprisingly, that the mechanical properties of the electro-active substrate did not affect device actuation. (C) 2011 Optical Society of America
Wavelet modelling of the gravity field by domain decomposition methods: an example over Japan
(2011)
With the advent of satellite gravity, large gravity data sets of unprecedented quality at low and medium resolution become available. For local, high resolution field modelling, they need to be combined with the surface gravity data. Such models are then used for various applications, from the study of the Earth interior to the determination of oceanic currents. Here we show how to realize such a combination in a flexible way using spherical wavelets and applying a domain decomposition approach. This iterative method, based on the Schwarz algorithms, allows to split a large problem into smaller ones, and avoids the calculation of the entire normal system, which may be huge if high resolution is sought over wide areas. A subdomain is defined as the harmonic space spanned by a subset of the wavelet family. Based on the localization properties of the wavelets in space and frequency, we define hierarchical subdomains of wavelets at different scales. On each scale, blocks of subdomains are defined by using a tailored spatial splitting of the area. The data weighting and regularization are iteratively adjusted for the subdomains, which allows to handle heterogeneity in the data quality or the gravity variations. Different levels of approximations of the subdomains normals are also introduced, corresponding to building local averages of the data at different resolution levels.
We first provide the theoretical background on domain decomposition methods. Then, we validate the method with synthetic data, considering two kinds of noise: white noise and coloured noise. We then apply the method to data over Japan, where we combine a satellite-based geopotential model, EIGEN-GL04S, and a local gravity model from a combination of land and marine gravity data and an altimetry-derived marine gravity model. A hybrid spherical harmonics/wavelet model of the geoid is obtained at about 15 km resolution and a corrector grid for the surface model is derived.