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Functional characterization of ROS-responsive genes, ANAC085 and ATR7, in Arabidopsis thaliana
(2023)
The CH2Cl2/MeOH (1:1) extract of Zanthoxylum holstzianum stem bark showed good antiplasmodial activity (IC50 2.5 +/- 0.3 and 2.6 +/- 0.3 mu g/mL against the W2 and D6 strains of Plasmodium falciparum, respectively). From the extract five benzophenanthridine alkaloids [8-acetonyldihydrochelerythrine (1), nitidine (2), dihydrochelerythine (3), norchelerythrine (5), arnottianamide (8)]; a 2-quinolone alkaloid [N-methylflindersine (4)]; a lignan [4,4 '-dihydroxy-3,3 '-dimethoxylignan-9,9 '-diyl diacetate (7)] and a dimer of a benzophenanthridine and 2-quinoline [holstzianoquinoline (6)] were isolated. The CH2Cl2/MeOH (1:1) extract of the root bark afforded 1, 3-6, 8, chelerythridimerine (9) and 9-demethyloxychelerythrine (10). Holstzianoquinoline (6) is new, and is the second dimer linked by a C-C bond of a benzophenanthridine and a 2-quinoline reported thus far. The compounds were identified based on spectroscopic evidence. Amongst five compounds (1-5) tested against two strains of P. falciparum, nitidine (IC50 0.11 +/- 0.01 mu g/mL against W2 and D6 strains) and norchelerythrine (IC50 value of 0.15 +/- 0.01 mu g/mL against D6 strain) were the most active.
#Gesellschaftslehre 9/10
(2023)
Das Spannungsverhältnis zwischen Meinungsfreiheit und allgemeinem Persönlichkeitsrecht hat das Bundesverfassungsgericht seit Jahrzehnten und wiederholt beschäftigt. Insbesondere in den letzten drei Jahren hatte sich das Gericht erneut intensiv damit zu befassen, einen angemessenen Ausgleich zwischen den sich gegenüberstehenden Grundrechtspositionen zu formulieren. Der Beitrag analysiert überblicksartig, inwieweit es in seinen neueren Entscheidungen seine bisherige Rechtsprechung fortgeführt, ergänzt oder gar nachjustiert hat.
The chapter describes the German procedure for obtaining compensation for wrongful convictions. Besides specific cases of compensation for convictions based on subsequently repealed legislation and claims arising from general official liability, German law provides a mechanism for compensation, insofar as a conviction is eliminated or mitigated in a retrial in criminal proceedings. Still within this retrial, the criminal court is called upon to determine whether a claim exists for compensation of material and/or non-material damages on the merits. The amount of compensation is assessed in a judicial administrative procedure at the request of the person concerned. The compensation for non-material harm is calculated on the basis of a lump sum of currently €75 per day of imprisonment; the extent of material harm must be submitted and proven by the person concerned. She has the right to take legal action in the civil courts against the decision on the amount, she has the right to take legal action in the civil courts.
Der Text analysiert den Gesetzesentwurf des Kriminalpolitischen Kreises zur Regelung des Notwehrexzesses und des Putativnotwehrexzesses, veröffentlicht unter Hoven/Mitsch in GA 2023, S. 241 ff., ausgehend vom aktuellen Diskussionsstand in Rechtsprechung und Literatur. Im Schwerpunkt widmet er sich dem Anwendungsbereich des Regelungsvorschlags, insbesondere der Reichweite des intensiven Notwehrexzesses, der Erfassung des extensiven Notwehrexzesses sowie den Voraussetzungen eines entschuldigenden Putativnotwehrexzesses. Er beruht auf einem Kommentar, den die Verfasserin im Juni 2023 auf dem Online-Workshop „Ein neues Konzept der Notwehr“ des kriminalpolitischen Kreises gehalten hat. Der Vortragsstil wurde beibehalten.
§§ 78a GVG
(2023)
#WAT 5/6
(2023)
The African weakly electric fish genus Campylomormyrus includes 15 described species mostly native to the Congo River and its tributaries. They are considered sympatric species, because their distribution area overlaps. These species generate species-specific electric organ discharges (EODs) varying in waveform characteristics, including duration, polarity, and phase number. They exhibit also pronounced divergence in their snout, i.e. the length, thickness, and curvature. The diversifications in these two phenotypical traits (EOD and snout) have been proposed as key factors promoting adaptive radiation in Campylomormyrus. The role of EODs as a pre-zygotic isolation mechanism driving sympatric speciation by promoting assortative mating has been examined using behavioral, genetical, and histological approaches. However, the evolutionary effects of the snout morphology and its link to species divergence have not been closely examined. Hence, the main objective of this study is to investigate the effect of snout morphology diversification and its correlated EOD to better understand their sympatric speciation and evolutionary drivers. Moreover, I aim to utilize the intragenus and intergenus hybrids of Campylomormyrus to better understand trait divergence as well as underlying molecular/genetic mechanisms involved in the radiation scenario. To this end, I utilized three different approaches: feeding behavior analysis, diet assessment, and geometric morphometrics analysis. I performed feeding behavior experiments to evaluate the concept of the phenotype-environment correlation by testing whether Campylomormyrus species show substrate preferences. The behavioral experiments showed that the short snout species exhibits preference to sandy substrate, the long snout species prefers a stone substrate, and the species with intermediate snout size does not exhibit any substrate preference. The experiments suggest that the diverse feeding apparatus in the genus Campylomormyrus may have evolved in adaptation to their microhabitats. I also performed diet assessments of sympatric Campylomormyrus species and a sister genus species (Gnathonemus petersii) with markedly different snout morphologies and EOD using NGS-based DNA metabarcoding of their stomach contents. The diet of each species was documented showing that aquatic insects such as dipterans, coleopterans and trichopterans represent the major diet component. The results showed also that all species are able to exploit diverse food niches in their habitats. However, comparing the diet overlap indices showed that different snout morphologies and the associated divergence in the EOD translated into different prey spectra. These results further support the idea that the EOD could be a ‘magic trait’ triggering both adaptation and reproductive isolation. Geometric morphometrics method was also used to compare the phenotypical shape traits of the F1 intragenus (Campylomormyrus) and intergenus (Campylomormyrus species and Gnathonemus petersii) hybrids relative to their parents. The hybrids of these species were well separated based on the morphological traits, however the hybrid phenotypic traits were closer to the short-snouted species. In addition, the likelihood that the short snout expressed in the hybrids increases with increasing the genetic distance of the parental species. The results confirmed that additive effects produce intermediate phenotypes in F1-hybrids. It seems, therefore, that morphological shape traits in hybrids, unlike the physiological traits, were not expressed straightforward.
Animal Welfare Versus Commercial Animal Use. Commercial Use of Animals Outside Agriculture: The forms of commercial animal use beyond agriculture are diverse. This includes, for example, circuses and working with film animals. However, the associated animal welfare problems have so far not been discussed in great detail. The authorities work mainly with non-binding expert opinions instead of legal regulations. The various instruments of the executive branch in this area will be dealt with, as well as possible new perspectives for animal protection law - and its limits.
Thomas Brehl (1957–2010)
(2023)
Körper, Geist und Schule
(2023)
Der Schulalltag ist oft von fehlender Mitarbeit und mangelnder Motivation der Schüler:innen geprägt. Um diesen Umstand entgegenzuwirken und die Lernsituation zu verbessern, stellt das praxisorientierte Buch einen neuen Ansatz vor: Lernen ist ein körperlicher Prozess und im Unterricht müssen Körper und Geist gleichermaßen angesprochen werden. Als Resultat wird eine körperintegrierende Lerntheorie entwickelt, die den Körper als Ausgangspunkt für Lernprozesse versteht und die Methode vermittelt, im Unterricht mit und durch den Körper zu lernen. Es beinhaltet wichtige Hinweise und Anregungen für die Unterrichtsgestaltung und zeigt mögliche Entwicklungen für die Didaktik und die allgemeine Schullandschaft auf.
Militärische Organisationen
(2023)
Die Spezifik militärischer Organisationen als Organisationstypus lässt sich aus der Bestimmung von Kriegen als Trias von „Gewalt + Organisation + Legitimation“ ableiten. Der Kern des Typs liegt entsprechend zum einen darin, die Fähigkeit zum organisierten Kampf zu entwickeln, d. h., bei seinen Mitgliedern die Fähigkeit zu erzeugen, Gewalt strategisch einzusetzen und diese auch selbst zu ertragen, und zum anderen, die Etablierung dieser Fähigkeit und ihren Einsatz auch zu legitimieren. Der Beitrag arbeitet darüber hinaus die Gemeinsamkeiten und Unterschiede der drei Subtypen militärischer Organisationen – reguläre Streitkräfte, private militärische Organisationen und Guerilla – heraus. Die Unterschiede liegen darin, wie sie sich legitimieren und finanzieren, wie sie ihr Personal akquirieren und ausbilden, und welche Bedeutung militärische Symbole und Rituale haben.
Militärische Sozialisation
(2023)
Zwar gibt es für jeden Beruf und in vielen Betrieben spezielle Ausbildungs- oder Traineeprogramme. Zumeist aber unterscheiden sich diese in Inhalt und der Art ihrer Vermittlung von der Ausbildung, die Soldaten und Soldatinnen erhalten. In diesem Beitrag wird der Begriff der militärischen Sozialisation in Bezug zu den neueren Konzeptionen des Sozialisationsbegriffs gesetzt. Danach werden verschiedene Sozialisationskonzepte, die auf die militärische Sozialisation angewendet wurden, vorgestellt. Dazu gehören Goffmans Theorie der totalen Institution, Foucaults Idee der Disziplinierung und entwicklungstheoretische Ansätze. Gezeigt wird aber auch, wie schwierig es ist, militärische Sozialisation empirisch zu fassen.
Hochwasser, Brände, Stromausfälle oder Vandalismus – Kulturgüter können durch verschiedene Ereignisse gefährdet oder gar zerstört werden. Die Notfallvorsorge für Kulturgüter gehört zwar zu den Kernaufgaben von Kultureinrichtungen, doch nach wie vor fehlen vielerorts die nötigen Ressourcen sowie eine konsequente Koordination aller für einen effektiven Kulturgutschutz notwendigen Partner. Das Diskussionspapier „Organisatorische Voraussetzungen der Notfallvorsorge für Kulturgüter“ fasst die bereits etablierten Methoden zur Notfallvorsorge zusammen und gibt Empfehlungen zur Weiterentwicklung.
Der Umgang mit Diversität in militärischen Organisationen wird auf drei Ebenen diskutiert: Auf der ersten geht es um Gemeinsamkeiten und die typischen Diskurse um Vielfalt in den Streitkräften. Auf der zweiten wird aufgezeigt, wie unterschiedlich in den Streitkräften um Diversität gerungen wird. Auf der dritten Ebene wird auf die mikropolitischen Auseinandersetzungen innerhalb von Streitkräften eingegangen. Deutlich gemacht wird in dem Beitrag, wie vielfältig der Umgang mit Diversität in den Streitkräften ist.
Ramadan in der Schule
(2023)
Wenn Schüler:innen im Ramadan fasten, müssen Schulen sowohl die Religionsausübung respektieren, als auch ihrem Bildungsauftrag nachkommen. Die daraus erwachsenden Herausforderungen werden vor allem an die Lehrkräfte und weniger an formale Bildungsstrukturen adressiert. Beim Versuch, diese widersprüchlichen Erwartungen als einzelne Lehrkraft zu bewältigen, entstehen Risiken für Diskriminierung. Unser Beitrag zeigt damit beispielhaft den Zusammenhang von schulorganisatorischen Rahmenbedingungen und Diskriminierungsrisiken auf.
In a comparison of three human service organisations in which the human body plays a key role, we examine how organisations regulate religious body practices. We concentrate on Muslim norms of dressing and undressing as a potential focal point of cultural and religious diversity. Inspired by Ray’s (2019) idea of racialized organizations, we assume that state-run organizations in Germany are characterized by a strong commitment to religious tolerance and non-discrimination but also marked by anti- Muslim sentiment prevalent among the German population. Our study looks for mechanism that explain how Human Service Organizations accommodate Muslim body practices. It draws on qualitative empirical data collected in state-run hospitals, schools and swimming pools in Germany. Our analyses show that the organizations draw on formal and informal rules at the organizational level to accommodate Islam. We identify five general organizational mechanisms that may hinder Muslim accommodation in human service organizations. In particular, we see a risk of decoupling between the expectation of religious tolerance and processes that lead to informal discrimination, driven mainly by the difficulty of controlling group dynamics among users.
Dieser Beitrag arbeitet die Spezifik von Verwaltungen als besonderen Organisationstypen heraus. Verwaltungen werden typischerweise und orientiert an Weber als Prototypen von Organisationen angesehen. Das erschwert die Aufgabenstellung. Ankerpunkte für die Beobachtung der Verwaltung als Organisationstypus sind die Besonderheit ihres Entscheidens, das Verhältnis zu Politik und Öffentlichkeit, die Etappen von Verwaltungsreformen und die Frage, ob in der Veränderungsresistenz möglicherweise eine Spezifität von Verwaltungen liegen könnte.
Einleitung
(2023)
Renewable energy changes the geopolitics of energy: whereas access to fossil fuel resources were key in the past, control over technology and industry will be key in the future. Consequently, different scholars have predicted that a growing focus on renewables will increase or decrease conflict in the energy sector, with no consensus on which is most likely. Here, we investigate the degree of conflict in renewable energy technology (RET) trade by analyzing data on 7041 trade conflicts 1995–2020, guided by two sets of theory-driven hypotheses. We show that RET trade is associated with more, longer, and more intense trade conflicts than other trade conflicts for 1995–2016. This supports the neorealist, geo-economic view of countries being willing to risk conflict to increase their share of a market rather than avoiding conflicts to increase the overall market size. It also contradicts the view that renewables will reduce conflict: at least in the past and regarding trade, it has increased rather than decreased conflict. For 2017–2020, this trend is reversed and RET trade became significantly less conflictive than other trade. Our findings imply that improved conflict-resolution institutions for RET are needed. We also suggest establishing specific institutions to govern trade in immature technologies.
Starch is an essential biopolymer produced by plants. Starch can be made inside source tissue (such as leaves) and sink tissue (such as fruits and tubers). Nevertheless, understanding how starch metabolism is regulated in source and sink tissues is fundamental for improving crop production.
Despite recent advances in the understanding of starch and its metabolism, there is still a knowledge gap in the source and sink metabolism. Therefore, this study aimed to summarize the state of the art regarding starch structure and metabolism inside plants. In addition, this study aimed to elucidate the regulation of starch metabolism in the source tissue using the leaves of a model organism, Arabidopsis thaliana, and the sink tissue of oil palm (Elaeis guineensis) fruit as a commercial crop.
The research regarding the source tissue will focus on the effect of the blockage of starch degradation on the starch parameter in leaves, especially in those of A. thaliana, which lack both disproportionating enzyme 2 (DPE2) and plastidial glucan phosphorylase 1 (PHS1) (dpe2/phs1). The additional elimination of phosphoglucan water dikinase (PWD), starch excess 4 (SEX4), isoamylase 3 (ISA3), and disproportionating enzyme 1 (DPE1) in the dpe2/phs1 mutant background demonstrates the alteration of starch granule number per chloroplast. This study provides insights into the control mechanism of granule number regulation in the chloroplast.
The research regarding the sink tissue will emphasize the relationship between starch metabolism and the lipid metabolism pathway in oil palm fruits. This study was conducted to observe the alteration of starch parameters, metabolite abundance, and gene expression during oil palm fruit development with different oil yields. This study shows that starch and sucrose can be used as biomarkers for oil yield in oil palms. In addition, it is revealed that the enzyme isoforms related to starch metabolism influence the oil production in oil palm fruit.
Overall, this thesis presents novel information regarding starch metabolism in the source tissue of A.thaliana and the sink tissue of E.guineensis. The results shown in this thesis can be applied to many applications, such as modifying the starch parameter in other plants for specific needs.
Droughts in São Paulo
(2023)
Literature has suggested that droughts and societies are mutually shaped and, therefore, both require a better understanding of their coevolution on risk reduction and water adaptation. Although the Sao Paulo Metropolitan Region drew attention because of the 2013-2015 drought, this was not the first event. This paper revisits this event and the 1985-1986 drought to compare the evolution of drought risk management aspects. Documents and hydrological records are analyzed to evaluate the hazard intensity, preparedness, exposure, vulnerability, responses, and mitigation aspects of both events. Although the hazard intensity and exposure of the latter event were larger than the former one, the policy implementation delay and the dependency of service areas in a single reservoir exposed the region to higher vulnerability. In addition to the structural and non-structural tools implemented just after the events, this work raises the possibility of rainwater reuse for reducing the stress in reservoirs.
Nach der einleitenden Bemerkung, dass die alteuropäische (mittelalterliche und früh neuzeitliche) Identität grundsätzlich konfessionell bestimmt war (Heiraten, Vergabe von Ämtern, Kriegsbündnisse u. a. orientierten sich an der Konfession), gliederte der Referent seinen Vortrag in zwei Abschnitte:
Teil 1: Reflexion über die christliche Identität Alteuropas an der Schwelle vom Mittelalter zur Neuzeit
Teil 2: Die Folgen von Katholischer Reform, Reformation und Gegenreformation für die europäische Geschichte im Konfessionellen Zeitalter, mit einigen Ausblicken auf das aufgeklärte, säkulare 18. Jahrhundert
Editorial
(2023)
Objective
Leaders differ in their personalities from non-leaders. However, when do these differences emerge? Are leaders "born to be leaders" or does their personality change in preparation for a leadership role and due to increasing leadership experience?
Method
Using data from the German Socio-Economic Panel Study, we examined personality differences between leaders (N = 2683 leaders, women: n = 967; 36.04%) and non-leaders (N = 33,663) as well as personality changes before and after becoming a leader.
Results
Already in the years before starting a leadership position, leaders-to-be were more extraverted, open, emotionally stable, conscientious, and willing to take risks, felt to have greater control, and trusted others more than non-leaders. Moreover, personality changed in emergent leaders: While approaching a leadership position, leaders-to-be (especially men) became gradually more extraverted, open, and willing to take risks and felt to have more control over their life. After becoming a leader, they became less extraverted, less willing to take risks, and less conscientious but gained self-esteem.
Conclusions
Our findings suggest that people are not simply "born to be leaders" but that their personalities change considerably in preparation for a leadership role and due to leadership experience. Some changes are transient, but others last for a long time.
Digitalization, as well as sustainability, are gaining increased relevance and have attracted significant attention in research and practice. However, the research already published about this topic examining digitalization in the retail sector does not consider the acceptance of related innovations, nor their impact on sustainability. Therefore, this article critically analyzes the acceptance of customers towards digital technologies in fashion stores as well as their impact on sustainability in the textile industry. The comprehensive analysis of the literature and the current state of research provide the basis of this paper. Theoretical models, such as the Technology-Acceptance-Model (TAM) and the Unified Theory of Acceptance and Use of Technology 2 (UTAUT 2) enable the evaluation of expectations and acceptance, as well as the assessment of possible inhibitory factors for the subsequent descriptive and statistical examination of the acceptance of digital technologies in fashion stores. The research on this subject was examined in a quantitative way. The key findings show that customers do accept digital technologies in fashion stores. The final part of this contribution describes the innovative Digitalization 4 Sustainability Framework which shows that digital technologies at the point of sale (PoS) in fashion stores could have a positive impact on sustainability. Overall, this paper shows that it is particularly important for fashion stores to concentrate on their individual strengths and customer needs as well as to indicate a more sustainable way by using digital technologies, in order to achieve added value for the customers and to set themselves apart from the competition while designing a more sustainable future. Moreover, fashion stores should make it a point of their honor to harness the power of digitalization for sake of sustainability and economic value creation.
Fälle zum Zivilprozessrecht
(2023)
Verfahrensrechtliche Klausuren sind häufig Gegenstand des Pflichtfachstudiums, vor allem aber auch im Schwerpunktbereichsstudium Zivilrechtspflege. Dieser Band enthält 15 Fälle aus allen Gebieten des Zivilprozessrechts, also aus dem Erkenntnisverfahren sowie dem Zwangsvollstreckungsrecht. Die Bearbeitung der Klausuren soll der Aneignung des Stoffes, dessen Wiederholung und der Vorbereitung auf Prüfungen dienen. Die Autorin hat die Fälle konsequent nach der Ausbildungsrelevanz ausgewählt, behandelt Streitfragen und gibt Aufbautipps. Eine Einführung in die Fallbearbeitungstechnik im Zivilprozessrecht rundet das Werk ab. Vorteile auf einen Blickdas gesamte prüfungsrelevante Wissen in Klausurformzahlreiche didaktische Hinweise mit Anleitung zur Bearbeitung von ZPO-Klausuren. Die Neuauflage berücksichtigt den aktuellen Stand von Gesetzgebung, Rechtsprechung und Literatur.
§§ 253-299a
(2023)
Die Kommentierung umfasst neben der Zivilprozessordnung auch die relevanten Nebengesetze (wie EGZPO, GVG, KapMuG und MediationsG) sowie das europäische und internationale Zivilprozessrecht. Selbstverständlich sind alle relevanten Gesetzesänderungen sowie die neuesten Entwicklungen in Rechtsprechung und Lehre berücksichtigt.
Umfassende Kommentierung zum Verfahren vor den Landgerichten bis zum Urteil.
Higher eco-efficiency will not be enough to slow global warming caused by climate change. To keep global warming to 2 degrees, people also need to reduce their consumption. At present, however, many who would be able to do so seem unwilling to comply. Given the threats of a runaway climate change, urgent measures are needed to promote less personal consumption. This study, therefore, examines whether social marketing consume-less appeals can be used to encourage consumers to voluntarily abstain from consumption. As part of an online experiment with nearly 2000 randomly sampled users of an online platform for sustainable consumption, we tested the effectiveness of five different “consume-less” appeals based on traditional advertising formats (including emotional, informational, and social claims). The study shows that consume-less appeals are capable of limiting personal desire to buy. However, significant differences in the effectiveness of the appeal formats used in this study were observed. In addition, we found evidence of rebound effects, which leads us to critically evaluate the overall potential of social marketing to promote more resource-conserving lifestyles. While commercial consumer-free appeals have previously been studied (e.g., Patagonia’s “Don’t Buy This Jacked”), this study on the effectiveness of non-commercial consume-free appeals is novel and provides new insights.
Consume-less appeals in social marketing can help reduce the lavish consumption in wealthy countries, which poses a major threat to the climate. This study experimentally examines the effectiveness of three different types of consume-less appeals (informative, social normative, and emotional appeals) on participants’ actual spending levels during a real shopping trip compared to a control group (no appeal). In addition, the study tests whether these appeals evoke negative rebounds (in terms of post-purchase climate donation) or positive rebounds (in terms of accepting post-purchase material giveaways). A field experiment in a grocery store in Germany with 170 participants shows that social normative and the emotional appeals reduce actual shopping spending. Informative and social normative appeals increase donations, and emotional appeals reduce the items of taken giveaways. The findings further support certain indirect impacts of the consume-less appeals on rebounds in terms of spending levels.
Purpose
Because steadily growing consumption is not beneficial for nature and climate and is not the same as increasing well-being, an anti-consumerism movement has formed worldwide. The renouncement of dispensable consumption will, however, only establish itself as a significant lifestyle if consumers do not perceive reduced consumption as a personal sacrifice. Since prior research has not yielded a consistent understanding of the relationship between anti-consumption and personal well-being, this paper aims to examine three factors about which theory implies that they may moderate this relationship: decision-control empowerment, market-control empowerment and the value of materialism.
Design/methodology/approach
The analysis is based on data from a large-scale, representative online survey (N = 1,398). Structural equation modelling with latent interaction effects is used to test how three moderators (decision-control empowerment, market-control empowerment and materialism) affect the relationship amongst four types of anti-consumption (e.g. voluntary simplicity) and three different well-being states (e.g. subjective well-being).
Findings
While both dimensions of empowerment almost always directly promote consumer well-being, significant moderation effects are present in only a few but meaningful cases. Although the materialism value tends to reduce consumers’ well-being, it improves the well-being effect of two anti-consumption styles.
Research limitations/implications
Using only one sample from a wealthy country is a limitation of the study. Researchers should replicate the findings in different nations and cultures.
Practical implications
Consumer affairs practitioners and commercial marketing for sustainably produced, high-quality and long-lasting goods can benefit greatly from these findings.
Social implications
This paper shows that sustainable marketing campaigns can more easily motivate consumers to voluntarily reduce their consumption for the benefit of society and the environment if a high level of market-control empowerment can be communicated to them.
Originality/value
This study provides differentiated new insights into the roles of consumer empowerment, i.e. both decision-control empowerment and market-control empowerment, and the value of materialism to frame specific relationships between different anti-consumption types and various well-being states.
Die DDR im Plural
(2023)
Atwood analyzes the effects of the 1963 U.S. measles vaccination on long-run labor market outcomes, using a generalized difference-in-differences approach. We reproduce the results of this paper and perform a battery of robustness checks. Overall, we confirm that the measles vaccination had positive labor market effects. While the negative effect on the likelihood of living in poverty and the positive effect on the probability of being employed are very robust across the different specifications, the headline estimate—the effect on earnings—is more sensitive to the exclusion of certain regions and survey years.