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We analyze a general class of difference operators H-epsilon = T-epsilon + V-epsilon on l(2)(((epsilon)Z)(d)), where V-epsilon is a multi-well potential and epsilon is a small parameter. We construct approximate eigenfunctions in neighbourhoods of the different wells and give weighted l(2)-estimates for the difference of these and the exact eigenfunctions of the associated Dirichlet-operators.
In the limit 0 we analyse the generators H of families of reversible jump processes in Rd associated with a class of symmetric non-local Dirichlet-forms and show exponential decay of the eigenfunctions. The exponential rate function is a Finsler distance, given as solution of a certain eikonal equation. Fine results are sensitive to the rate function being C2 or just Lipschitz. Our estimates are analogous to the semiclassical Agmon estimates for differential operators of second order. They generalize and strengthen previous results on the lattice Zd. Although our final interest is in the (sub)stochastic jump process, technically this is a pure analysis paper, inspired by PDE techniques.
Recent work on mutation-selection models has revealed that, under specific assumptions on the fitness function and the mutation rates, asymptotic estimates for the leading eigenvalue of the mutation-reproduction matrix may be obtained through a low-dimensional maximum principle in the limit N --> infinity (where N, or N-d with d greater than or equal to 1, is proportional to the number of types). In order to extend this variational principle to a larger class of models, we consider here a family of reversible matrices of asymptotic dimension N-d and identify conditions under which the high-dimensional Rayleigh-Ritz variational problem may be reduced to a low-dimensional one that yields the leading eigenvalue up to an error term of order 1/N. For a large class of mutation-selection models, this implies estimates for the mean fitness, as well as a concentration result for the ancestral distribution of types
We analyze a general class of difference operators H(epsilon) = T(epsilon) + V(epsilon) on l(2)((epsilon Z)(d)), where V(epsilon) is a one-well potential and epsilon is a small parameter. We construct formal asymptotic expansions of WKB-type for eigenfunctions associated with the low lying eigenvalues of H(epsilon). These are obtained from eigenfunctions or quasimodes for the operator H(epsilon), acting on L(2)(R(d)), via restriction to the lattice (epsilon Z)(d).
For a general class of difference operators H-epsilon = T-epsilon + V-epsilon on l(2) ((epsilon Z)(d)), where V- epsilon is a multi-well potential and a is a small parameter. we analyze the asymptotic behavior as epsilon -> 0 of the (low-lying) eigenvalues and eigenfunctions. We show that the first it eigenvalues of H converge to the first it eigenvalues of the direct suns of harmonic oscillators oil R-d located at the several wells. Our proof is microlocal.
Metastability in reversible diffusion processes : I. Sharp asymptotics for capacities and exit times
(2004)
We develop a potential theoretic approach to the problem of metastability for reversible diffusion processes with generators of the form -epsilonDelta+ delF(.) del on R-d or subsets of R-d, where F is a smooth function with finitely many local minima. In analogy to previous work on discrete Markov chains, we show that metastable exit times from the attractive domains of the minima of F can be related, up to multiplicative errors that tend to one as epsilon down arrow 0, to the capacities of suitably constructed sets. We show that these capacities can be computed, again up to multiplicative errors that tend to one, in terms of local characteristics of F at the starting minimum and the relevant saddle points. As a result, we are able to give the first rigorous proof of the classical Eyring - Kramers formula in dimension larger than 1. The estimates on capacities make use of their variational representation and monotonicity properties of Dirichlet forms. The methods developed here are extensions of our earlier work on discrete Markov chains to continuous diffusion processes