Refine
Year of publication
- 2019 (183) (remove)
Document Type
- Article (137)
- Doctoral Thesis (25)
- Postprint (16)
- Other (2)
- Review (2)
- Conference Proceeding (1)
Is part of the Bibliography
- yes (183)
Keywords
- DFT calculations (3)
- DNA origami (3)
- LIBS (3)
- SERS (3)
- ferroelectricity (3)
- hybrid perovskites (3)
- inorganic chemistry (3)
- nanoparticles (3)
- photovoltaic materials (3)
- ring-opening polymerization (3)
- structure elucidation (3)
- 2-Azaspiro[4.5]deca-1-ones (2)
- Cis- and trans-form (2)
- Configuration (2)
- Conformation (2)
- Degradation (2)
- Europium (2)
- Lactams (2)
- NICS (2)
- NMR (2)
- SEM (2)
- X-ray diffraction (2)
- amorphous carbon (2)
- antifouling (2)
- biomaterial (2)
- cement admixtures (2)
- cement hydration (2)
- coatings (2)
- conformational analysis (2)
- crosslinking (2)
- crown compounds (2)
- elemental composition (2)
- endoperoxides (2)
- fluorescence lifetime (2)
- fluorescent probes (2)
- gas adsorption (2)
- glycopolymers (2)
- hydrophilic polymers (2)
- iron (2)
- isomerization (2)
- laser-induced breakdown spectroscopy (2)
- luminescence (2)
- microgels (2)
- nanocomposite (2)
- nanoflowers (2)
- nanolenses (2)
- nanoparticle dimers (2)
- nanostructures (2)
- nanotriangles (2)
- optical-properties (2)
- polyzwitterions (2)
- proximal soil sensing (2)
- ratiometric (2)
- self-assembly (2)
- sers (2)
- singlet oxygen (2)
- size (2)
- sodium (2)
- soil nutrients (2)
- step (2)
- supercapacitors (2)
- surface plasmon resonance (2)
- sustainable chemistry (2)
- ultrafast (2)
- wavelength (2)
- (TSNMRS) (1)
- 1-Methylthio-1-phenyl-1-silacyclohexane (1)
- 2-deoxy-D-ribose-5-phoshphate aldolase (1)
- 2-oxazoline (1)
- 3D flower superstructures (1)
- 3D printed flow-cell (1)
- 4-nitrophenol (1)
- ATCUN motif (1)
- Absorption (1)
- Adipocyte (1)
- Ammoniak (1)
- Analysis scattering kernel (1)
- Anti-Plasmodial activity (1)
- Antimicrobial (1)
- Antioxidant (1)
- Apoptosis (1)
- Aromaten (1)
- Benzyne-allene or cumulene-like structure (1)
- Beschichtung (1)
- Biflavonoid (1)
- Bifunctional catalysts (1)
- Bindung (1)
- Biomasseverwertung (1)
- Biosensor (1)
- Block Copolymer (1)
- Block copolymers (1)
- Bottom-up fabrication (1)
- C (1)
- C-13 chemical shift (1)
- C-13 chemical shifts (1)
- C-Arlyglykosid (1)
- Cancer (1)
- Carbene or zwitterions (1)
- Carica papaya seeds (1)
- Ceroxid (1)
- Chalkon (1)
- Conformational analysis (1)
- Cryo-SEM (1)
- DFT (1)
- DFT and MP2 calculations (1)
- DFT and MP2 simulation (1)
- DNA radiation damage (1)
- DNA strand breaks (1)
- Docking study (1)
- Drug loading (1)
- E. coli (1)
- Eisen (1)
- Electrodeposition (1)
- Electrosensing (1)
- Endoperoxide (1)
- Energiespeichermechanismus (1)
- Energy storage (1)
- European pear (1)
- Eutectic mixture (1)
- F-C coupling constants (1)
- FhuA (1)
- Filmbildner (1)
- Fluoroionophore (1)
- Fruit quality (1)
- Fusicoccane diterpenes (1)
- Gas phase electron diffraction (1)
- Gas-sorption (1)
- Gasadsorption (1)
- Glykan-Protein-Wechselwirkung (1)
- Glykopolymere (1)
- H2O2 (1)
- HMF oxidation (1)
- HRTEM (1)
- Hepcidin (1)
- Hydrolytic stability (1)
- Hypoestes verticillaris (1)
- ITC (1)
- Ibuprofen (1)
- In situ coating (1)
- Intracellular bacteria (1)
- Ionic liquid (1)
- Iron oxide (1)
- Iron/silver microflowers (1)
- Iso-chemical shielding surfaces (ICSS) (1)
- Isoflavone (1)
- Kalium- und Natrium-Ionen (1)
- Kohlenstoffmaterialien (1)
- Langmuir monolayer (1)
- Langmuir-Schafer films (1)
- Large-size (1)
- Lattice Boltzmann methods (1)
- Lektine (1)
- Levoglucosenol (1)
- Ligand design (1)
- Lignans (1)
- Lithium ion battery (1)
- Low-temperature C-13 and Si-29 NMR (1)
- MOF-derived catalysts (1)
- MS (1)
- Macrophage (1)
- Magnetic properties (1)
- Magnetite and gold nanoparticles (1)
- Magnetization measurements (1)
- Main text (1)
- Male (1)
- Matsuda-Heck reaction (1)
- Matsuda-Heck-Reaktion (1)
- Melt crystallization (1)
- Mesomeric equilibrium of carbene/zwitterion (1)
- Metall (1)
- Methylmercury (1)
- Mikrogel-Array (1)
- Mikrogele (1)
- Mikrogelketten (1)
- Mikrogelstränge (1)
- Molecular interaction design (1)
- Molekulardynamik (1)
- Monte-Carlo (1)
- Monte-Carlo simulations (1)
- Multi-drug resistance (1)
- N-2 fixation (1)
- N-2 reduction (1)
- N2 fixation (1)
- N2-Fixierung (1)
- NMR spectroscopy (1)
- NMR structure (1)
- Nanohybrid (1)
- Nanomaterialien (1)
- Nanoparticles (1)
- Nanostructured (1)
- Nanostructures (1)
- Ni nanodots (1)
- Nonenzymatic (1)
- Oberflächenbeschichtung (1)
- Oligodepsipeptide (1)
- Optical fiber (1)
- Optical parameter set (1)
- Ordering transitions (1)
- Organic chemistry (1)
- Organic electrode (1)
- Ormocarpum kirkii (1)
- PDLLGA (1)
- PEG6000 (1)
- PLS regression (1)
- Particle shape (1)
- Pastillation (1)
- Peptid (1)
- Phagocytosis (1)
- Phantoms (1)
- Photochemistry (1)
- Physical chemistry (1)
- Pickering emulsions (1)
- Pluronics (1)
- Poly(carbonate-urea-urethane)s (1)
- Poly(epsilon-caprolactone) (1)
- Poly(n-butyl acrylate) (1)
- Polylactid (1)
- Polymer (1)
- Polymer micronetwork colloids (1)
- Polymeric substrate (1)
- Polymerisation (1)
- Porösität (1)
- RAFT (1)
- RAFT polymerization (1)
- Radiative transport (1)
- Redox polymer (1)
- Reduced scattering coefficient (1)
- Ring current effect (1)
- Ring tensiometry (1)
- Ringschlussmetathese (1)
- SRG formation in polymer brushes (1)
- Scattering (1)
- Schwingungsspektroskopie (1)
- Selbstorganisation (1)
- Selektivität (1)
- Sex (1)
- Singulettsauerstoff (1)
- Solvothermal synthesis (1)
- Spatially resolved spectroscopy (1)
- Spektroskopie (1)
- Spherical polyelectrolyte brushes (1)
- Stereokomplexierung (1)
- Stickstoffdotiert (1)
- Stärke (1)
- Supercapacitor (1)
- Superkondensatoren (1)
- Supramolecular chemistry (1)
- Surface plasmon resonance (1)
- Theoretical chemistry (1)
- Thioredoxin (1)
- Through-space NMR shieldings (TSNMRS) (1)
- Trough-space NMR shieldings (TSNMRS) (1)
- UV (1)
- VEGF (1)
- Water splitting (1)
- Ylide (1)
- abbaubares Polymer (1)
- amide ligand (1)
- ammonia (1)
- ammonia synthesis (1)
- anion substitution (1)
- anisotropic microgels (1)
- anisotropic structures (1)
- anthracenes (1)
- aromats (1)
- artificial muscles (1)
- aryl C-glycoside (1)
- azobenzene containing surfactants (1)
- azobenzenes (1)
- basement membrane (1)
- binding (1)
- biomass valorization (1)
- biomaterial-tissue interface (1)
- biomaterials (1)
- biomedical (1)
- biomimetic (chemical reaction) (1)
- block copolymer (1)
- block-copolymer (1)
- blood tests (1)
- brushes (1)
- carbene electron deficiency (1)
- carbenes (1)
- carbon (1)
- carbon fibers (1)
- carbon materials (1)
- catalyst (1)
- catechol (1)
- cationic ring-opening polymerization (1)
- cell adhesion (1)
- cerium oxide (1)
- chalcogens (1)
- chalcon (1)
- chemical synthesis (1)
- ciprofloxacin (1)
- clay (1)
- coating (1)
- cobamides (1)
- cold (1)
- collagen-IV (1)
- colloidal chemistry (1)
- composite electrodes (1)
- controlled-release (1)
- copper (1)
- copper complex (1)
- core-shell nanoparticles (1)
- cross-linking (1)
- crystallization (1)
- cycloaddition (1)
- cytochrome P450 (1)
- dedifferentiation (1)
- degradable polymer (1)
- degradable polymers (1)
- density functional calculations (1)
- dependent scattering (1)
- direct electron transfer (1)
- disinfection (1)
- dissociative electron attachment (1)
- diversiform structures (1)
- drug discovery (1)
- electrochemical impedance spectroscopy (1)
- electrochemistry (1)
- electropolymerization (1)
- electrospinning (1)
- elegans (1)
- ellipsometry (1)
- energy storage (1)
- energy storage mechanism (1)
- enthalpy-entropy compensation (EEC) (1)
- environmental remediation (1)
- enzymatic degradation (1)
- enzymatically active membrane (1)
- enzyme immobilization (1)
- enzyme/polymer conjugate (1)
- ethanolamine phosphate (1)
- extracellular matrix modifying enzymes (1)
- fiber meshes (1)
- field test (1)
- film former (1)
- films (1)
- fluoroionophore (1)
- fouling release (1)
- galectin-3 (1)
- gas-phase reactions (1)
- gaussian processes (1)
- gelatin-based hydrogels (1)
- glycan-protein interaction (1)
- glycomaterials (1)
- gold nanostructures (1)
- heiße Elektronen (1)
- hepcidin (1)
- hepcidin-25 (1)
- heteroatoms (1)
- hierarchical self-assembly (1)
- hierarchically porous carbon (1)
- high concentrations (1)
- high energy density (1)
- hohe Energiedichte (1)
- hybrid materials (1)
- hybrid nanomaterials (1)
- hydrogel (1)
- hydrogels (1)
- hydrogen (1)
- hydrogen isotopes (1)
- implants (1)
- in vitro (1)
- induced pluripotent stem cells (1)
- interfacial recombination (1)
- interferometry (1)
- intra- and extracellular (1)
- intra- und extrazellulär (1)
- isotope separation (1)
- kinetic of cis-trans isomerization (1)
- kinetics (1)
- langmuir monolayer (1)
- lasso (1)
- lectins (1)
- levoglucosenol (1)
- light scattering (1)
- lipid (1)
- lithium-ion batteries (1)
- low-energy electrons (1)
- low-temperature NMR spectroscopy (1)
- magnetosensitivity (1)
- marine biofouling (1)
- mechanical property (1)
- mesenchymal stem cells (1)
- metal (1)
- metal complex (1)
- metal organic frameworks (1)
- metal peptide (1)
- metal-organic frameworks (1)
- metal-organic mesocrystals (1)
- metallocarbohydrates (1)
- metallopeptide (1)
- metalloprotein (1)
- metallorganische Netzwerke (1)
- metathesis (1)
- micro/mesoporous (1)
- microgel array (1)
- microgel chains (1)
- microgel strands (1)
- microwave (1)
- modified Mannich reaction (1)
- modulus (1)
- molecular dynamics (1)
- molecularly imprinted polymers (1)
- multidrug-resistant Escherichia coli (1)
- multivalency (1)
- nachhaltige Chemie (1)
- nanocarriers (1)
- nanocomposite material (1)
- nanocomposites (1)
- nanofillers (1)
- nanomaterials (1)
- nanomedicine (1)
- nickel (1)
- nitrogen-doped (1)
- nitrogen-doped carbon (1)
- non-metal catalysis (1)
- non-noble metal catalysts (1)
- norcobamide biosynthesis (1)
- nucleus-independent chemical shifts (NICS) (1)
- nutrients (1)
- open-circuit voltage (1)
- optical imaging (1)
- optical sensor (1)
- ortho-quinone methide (o-QMs) (1)
- particulate (1)
- peptide (1)
- perovskite solar cells (1)
- phenolic acid (1)
- photocatalysts (1)
- photochemistry (1)
- photoluminescence (1)
- photooxygenation (1)
- photosensitive azobenzene containing surfactant (1)
- photosensitive polymer brushes (1)
- plasmonic chemistry (1)
- plasmonische Chemie (1)
- poly(epsilon-caprolactone) (1)
- poly(ester amide)s (1)
- polyamines (1)
- polyester (1)
- polylactide (1)
- polymer (1)
- polymer fillers (1)
- polymerization (1)
- polymers (1)
- polymersome spreading (1)
- pore templating (1)
- porosity (1)
- porous carbon (1)
- porous carbon-based materials (1)
- porous carbons (1)
- porous silicon (1)
- poröse Kohlenstoffe (1)
- porösen Materialien auf Kohlenstoffbasis (1)
- potassium and sodium ions (1)
- precision agriculture (1)
- protein (1)
- protein imprinting (1)
- proteins (1)
- purity (1)
- quantum sieving (1)
- racemization (1)
- reaction mechanisms (1)
- reactive oxygen species (1)
- redox polymers (1)
- reference material (1)
- responsive (1)
- reversible and irreversible structuring of polymer brushes (1)
- reversible shape-memory effect (1)
- ring closing metathesis (1)
- ringöffnende Polymerisation (1)
- sediment (1)
- selectivity (1)
- self-healing (1)
- semi-crystalline (1)
- sensitizers (1)
- serine phosphate decarboxylase (1)
- shape (1)
- shape memory (1)
- shape-memory (1)
- silacyclohexanes (1)
- siloxanes (1)
- smart materials (1)
- sodium storage mechanism (1)
- sodium-ion capacitors (1)
- soft actuators (1)
- soil (1)
- solid-supported biomimetic membranes (1)
- solvent effect (1)
- spectroscopy (1)
- spherical polyelectrolyte (1)
- starch (1)
- stem cell adhesion (1)
- stereocomplexation (1)
- strong polyelectrolyte brush (1)
- sunscreen (1)
- surface coating (1)
- surface modification (1)
- surfaces (1)
- synthosomes (1)
- tamplat unterstütze Anordnung von weichen Partikeln (1)
- template assisted alignment of soft particles (1)
- theoretical chemistry (1)
- theoretische Chemie (1)
- thermal transformation mechanism (1)
- thermodynamics (1)
- thermoplastics (1)
- thrombogenicity (1)
- through space NMR shieldings (1)
- two dimensional network (1)
- upconversion nanoparticles (1)
- vacuum-UV radiation (1)
- vascular graft (1)
- vibrational spectroscopy (1)
- vis spectroscopy (1)
- water (1)
- water remediation (1)
- zwitterions (1)
Institute
- Institut für Chemie (183) (remove)
Experimental and kinetic modelling studies are presented to investigate the mechanism of 3,3 ',5,5 '-tetramethylbenzidine (TMB) oxidation by hydrogen peroxide (H2O2) catalyzed by peroxidase-like Pt nanoparticles immobilized in spherical polyelectrolyte brushes (SPB-Pt). Due to the high stability of SPB-Pt colloidal, this reaction can be monitored precisely in situ by UV/VIS spectroscopy. The time-dependent concentration of the blue-colored oxidation product of TMB expressed by different kinetic models was used to simulate the experimental data by a genetic fitting algorithm. After falsifying the models with abundant experimental data, it is found that both H2O2 and TMB adsorb on the surface of Pt nanoparticles to react, indicating that the reaction follows the Langmuir-Hinshelwood mechanism. A true rate constant k, characterizing the rate-determining step of the reaction and which is independent on the amount of catalysts used, is obtained for the first time. Furthermore, it is found that the product adsorbes strongly on the surface of nanoparticles, thus inhibiting the reaction. The entire analysis provides a new perspective to study the catalytic mechanism and evaluate the catalytic activity of the peroxidase-like nanoparticles.
Poly(lactide-co-glycolide)s are commercially available degradable implant materials, which are typically selected based on specifications given by the manufacturer, one of which is their molecular weight. Here, we address the question whether variations in the chain length and their distribution affect the degradation behavior of Poly[(rac-lactide)-co-glycolide]s (PDLLGA). The hydrolysis was studied in ultrathin films at the air-water interface in order to rule out any morphological effects. We found that both for purely hydrolytic degradation as well as under enzymatic catalysis, the molecular weight has very little effect on the overall degradation kinetics of PDLLGAs. The quantitative analysis suggested a random scission mechanism. The monolayer experiments showed that an acidic micro-pH does not accelerate the degradation of PDLLGAs, in contrast to alkaline conditions. The degradation experiments were combined with interfacial rheology measurements, which showed a drastic decrease of the viscosity at little mass loss. The extrapolated molecular weight behaved similar to the viscosity, dropping to a value near to the solubility limit of PDLLGA oligomers before mass loss set in. This observation suggests a solubility controlled degradation of PDLLGA. Conclusively, the molecular weight affects the degradation of PDLLGA devices mostly in indirect ways, e.g. by determining their morphology and porosity during fabrication. Our study demonstrates the relevance of the presented Langmuir degradation method for the design of controlled release systems.
The numerical prediction of radiative transport is a challenging task due to the complexity of the radiative transport equation. We apply the lattice Boltzmann method (LBM), originally developed for fluid flow problems, to solve the radiative transport in volume. One model (meso RTLBM) is derived directly from a discretization of the radiative transport equation, yielding in a precise but numerical costly scheme. The second model (macro RTLBM) solves the Helmholtz equation, which is a proper approximation for highly scattering volumes. Both numerical algorithms are validated against Monte-Carlo data for a set of 35 optical parameters, which correspond to radiative transport ranging from ballistic to diffuse regimes. Together with a set of four benchmark simulations, the comprehensive validation concludes the overall quality and detects asymptotic trends for radiative transport LBM. Furthermore, an accuracy map is presented, which summarizes the error for all parameters. This graph allows to determine the validity range for both radiative transport LBM at a glance. Finally, comprehensive guidelines are formulated to facilitate the choice of the radiative transport LBM model.
Both the C-13 chemical shift and the calculated anisotropy effect (spatial magnetic properties) of the electron-deficient centre of stable, crystalline, and structurally characterized carbenes have been employed to unequivocally characterize potential resonance contributors to the present mesomerism (carbene, ylide, betaine, and zwitter ion) and to determine quantitatively the electron deficiency of the corresponding carbene carbon atom. Prior to that, both structures and C-13 chemical shifts were calculated and compared with the experimental delta(C-13)/ppm values and geometry parameters (as a quality criterion for obtained structures).
Enhancement of human induced pluripotent stem cells adhesion through multilayer laminin coating
(2019)
Bioengineered cell substrates are a highly promising tool to govern the differentiation of stem cells in vitro and to modulate the cellular behavior in vivo. While this technology works fine for adult stem cells, the cultivation of human induced pluripotent stem cells (hiPSCs) is challenging as these cells typically show poor attachment on the bioengineered substrates, which among other effects causes substantial cell death. Thus, very limited types of surfaces have been demonstrated suitable for hiPSC cultures. The multilayer coating approach that renders the surface with diverse chemical compositions, architectures, and functions can be used to improve the adhesion of hiPSCs on the bioengineered substrates. We hypothesized that a multilayer formation based on the attraction of molecules with opposite charges could functionalize the polystyrene (PS) substrates to improve the adhesion of hiPSCs. Polymeric substrates were stepwise coated, first with dopamine to form a polydopamine (PDA) layer, second with polylysine and last with Laminin-521. The multilayer formation resulted in the variation of hydrophilicity and chemical functionality of the surfaces. Hydrophilicity was detected using captive bubble method and the amount of primary and secondary amines on the surface was quantified by fluorescent staining. The PDA layer effectively immobilized the upper layers and thereby improved the attachment of hiPSCs. Cell adhesion was enhanced on the surfaces coated with multilayers, as compared to those without PDA and/or polylysine. Moreover, hiPSCs spread well over this multilayer laminin substrate. These cells maintained their proliferation capacity and differentiation potential. The multilayer coating strategy is a promising attempt for engineering polymer-based substrates for the cultivation of hiPSCs and of interest for expanding the application scope of hiPSCs.
Ihre außergewöhnlich hohen Konversionseffizienzen von über 20 % und die einfache Zellherstellung machen Hybridperowskite zu heißen Kandidaten für alternative Solarzellenmaterialien. CH3NH3PbI3 als Archetyp dieser Materialklasse besitzt außergewöhnliche Eigenschaften wie eine sehr effiziente Umwandlung von Solarenergie, wobei besonders Ferroelektrizität als mögliche Erklärung in den Fokus gerückt ist. Diese erfordert allerdings eine nicht-zentrosymmetrische Kristallstruktur als notwendige Voraussetzung. Wir stellen hier eine Erklärung des Symmetriebruchs in diesem Material auf kristallographischem, d. h. fernordnungs-basiertem, Wege vor. Während das Molekülkation CH3NH3+ intrinsisch polar ist, ist es extrem fehlgeordnet und kann deshalb nicht die einzige Erklärung darstellen. Es verzerrt allerdings das umgebende Kristallgitter und ruft dadurch eine Verschiebung der Iod-Atome von den zentrosymmetrischen Positionen hervor.
Ihre außergewöhnlich hohen Konversionseffizienzen von über 20 % und die einfache Zellherstellung machen Hybridperowskite zu heißen Kandidaten für alternative Solarzellenmaterialien. CH3NH3PbI3 als Archetyp dieser Materialklasse besitzt außergewöhnliche Eigenschaften wie eine sehr effiziente Umwandlung von Solarenergie, wobei besonders Ferroelektrizität als mögliche Erklärung in den Fokus gerückt ist. Diese erfordert allerdings eine nicht-zentrosymmetrische Kristallstruktur als notwendige Voraussetzung. Wir stellen hier eine Erklärung des Symmetriebruchs in diesem Material auf kristallographischem, d. h. fernordnungs-basiertem, Wege vor. Während das Molekülkation CH3NH3+ intrinsisch polar ist, ist es extrem fehlgeordnet und kann deshalb nicht die einzige Erklärung darstellen. Es verzerrt allerdings das umgebende Kristallgitter und ruft dadurch eine Verschiebung der Iod-Atome von den zentrosymmetrischen Positionen hervor.
Excellent conversion efficiencies of over 20% and facile cell production have placed hybrid perovskites at the forefront of novel solar cell materials, with CH3NH3PbI3 being an archetypal compound. The question why CH3NH3PbI3 has such extraordinary characteristics, particularly a very efficient power conversion from absorbed light to electrical power, is hotly debated, with ferroelectricity being a promising candidate. This does, however, require the crystal structure to be non-centrosymmetric and we herein present crystallographic evidence as to how the symmetry breaking occurs on a crystallographic and, therefore, long-range level. Although the molecular cation CH3NH3+ is intrinsically polar, it is heavily disordered and this cannot be the sole reason for the ferroelectricity. We show that it, nonetheless, plays an important role, as it distorts the neighboring iodide positions from their centrosymmetric positions.
Excellent conversion efficiencies of over 20% and facile cell production have placed hybrid perovskites at the forefront of novel solar cell materials, with CH3NH3PbI3 being an archetypal compound. The question why CH3NH3PbI3 has such extraordinary characteristics, particularly a very efficient power conversion from absorbed light to electrical power, is hotly debated, with ferroelectricity being a promising candidate. This does, however, require the crystal structure to be non-centrosymmetric and we herein present crystallographic evidence as to how the symmetry breaking occurs on a crystallographic and, therefore, long-range level. Although the molecular cation CH3NH3+ is intrinsically polar, it is heavily disordered and this cannot be the sole reason for the ferroelectricity. We show that it, nonetheless, plays an important role, as it distorts the neighboring iodide positions from their centrosymmetric positions.
The impact of the orientation of zwitterionic groups, with respect to the polymer backbone, on the antifouling performance of thin hydrogel films made of polyzwitterions is explored. In an extension of the recent discussion about differences in the behavior of polymeric phosphatidylcholines and choline phosphates, a quasi-isomeric set of three poly(sulfobetaine methacrylate)s is designed for this purpose. The design is based on the established monomer 3-[N-2-(methacryloyloxy)ethyl-N,N-dimethyl]ammonio-propane-1-sulfonate and two novel sulfobetaine methacrylates, in which the positions of the cationic and the ionic groups relative to the polymerizable group, and thus also to the polymer backbone, are altered. The effect of the varied segmental dipole orientation on their water solubility, wetting behavior by water, and fouling resistance is compared. As model systems, the adsorption of the model proteins bovine serum albumin (BSA), fibrinogen, and lysozyme onto films of the various polyzwitterion surfaces is studied, as well as the settlement of a diatom (Navicula perminuta) and barnacle cyprids (Balanus improvisus) as representatives of typical marine fouling communities. The results demonstrate the important role of the zwitterionic group's orientation on the polymer behavior and fouling resistance