Refine
Year of publication
Document Type
- Doctoral Thesis (1051) (remove)
Keywords
- Arabidopsis thaliana (18)
- Klimawandel (13)
- climate change (12)
- Arabidopsis (11)
- Evolution (10)
- Ökologie (10)
- Biosensor (9)
- Modellierung (9)
- Transkriptionsfaktoren (9)
- metabolism (9)
- Photosynthese (8)
- Stoffwechsel (8)
- Systembiologie (8)
- evolution (8)
- metabolomics (8)
- photosynthesis (8)
- transcription factors (8)
- Biodiversität (7)
- DNA (7)
- ecology (7)
- Antikörper (6)
- Bewegungsökologie (6)
- Centrosom (6)
- Dictyostelium (6)
- Escherichia coli (6)
- Serotonin (6)
- biodiversity (6)
- biosensor (6)
- movement ecology (6)
- serotonin (6)
- transcriptomics (6)
- Chlamydomonas (5)
- Cyanobakterien (5)
- Dielektrophorese (5)
- Phosphorylierung (5)
- Speicheldrüse (5)
- adaptation (5)
- biofilm (5)
- cell wall (5)
- dielectrophoresis (5)
- ecological modelling (5)
- metabolic networks (5)
- modelling (5)
- peptide (5)
- plant (5)
- protein folding (5)
- synthetic biology (5)
- systems biology (5)
- thermodynamic stability (5)
- Ackerschmalwand (4)
- Anpassung (4)
- Bakteriophagen (4)
- Bioinformatik (4)
- Genomik (4)
- Influenza (4)
- Koexistenz (4)
- Mikrofluidik (4)
- Mikrotubuli (4)
- Pflanzen (4)
- Protein (4)
- Proteinfaltung (4)
- Saccharomyces cerevisiae (4)
- Solanum tuberosum (4)
- Transkriptionsfaktor (4)
- Transkriptomik (4)
- Zellwand (4)
- antibody (4)
- cyanobacteria (4)
- diversity (4)
- dopamine (4)
- fluctuating light (4)
- genomics (4)
- mathematische Modellierung (4)
- metabolite profiling (4)
- methanogenic archaea (4)
- microplastics (4)
- next generation sequencing (4)
- phosphorylation (4)
- protein (4)
- salivary gland (4)
- synthetische Biologie (4)
- thermodynamische Stabilität (4)
- transcription factor (4)
- ökologische Modellierung (4)
- Arctic (3)
- Arktis (3)
- Ausbreitung (3)
- Bakterien (3)
- Biochemie (3)
- Biofilm (3)
- Datenbank (3)
- Diabetes (3)
- Diversität (3)
- Dopamin (3)
- E. coli (3)
- Ecology (3)
- Entwicklung (3)
- Enzyme (3)
- Enzymkinetik (3)
- Epigenetik (3)
- Fluoreszenzmikroskopie (3)
- GPCR (3)
- Genexpression (3)
- Honigbiene (3)
- Metabolit (3)
- Metabolomik (3)
- Microarray (3)
- Mikrobiologie (3)
- Mikroplastik (3)
- Naturstoffe (3)
- PKA (3)
- Peptid (3)
- Populationsdynamik (3)
- Rezeptor (3)
- Sekundärmetabolite (3)
- Siberia (3)
- Sibirien (3)
- Speichel (3)
- Stärke (3)
- Tailspike (3)
- Transkriptom (3)
- Tyramin (3)
- Virus (3)
- Zooplankton (3)
- ancient DNA (3)
- biogenic amines (3)
- biogeography (3)
- bioinformatics (3)
- centrosome (3)
- chloroplast (3)
- coexistence (3)
- conservation (3)
- dispersal (3)
- enzyme (3)
- epigenetics (3)
- fluorescence microscopy (3)
- functional traits (3)
- global change (3)
- influenza (3)
- leaf (3)
- lokale Anpassung (3)
- mathematical modeling (3)
- mathematical modelling (3)
- metabolic engineering (3)
- metabolite (3)
- methane (3)
- miRNA (3)
- microarray (3)
- monoclonal antibodies (3)
- monoklonale Antikörper (3)
- movement (3)
- population dynamics (3)
- potato (3)
- proteasomal degradation (3)
- salmonella (3)
- starch (3)
- translation (3)
- Adhäsion (2)
- Agentenbasierte Modelle (2)
- Agrarökologie (2)
- Aktivität (2)
- Aldehydoxidase (2)
- Anthropometrie (2)
- Antibiotikaresistenz (2)
- BMI (2)
- Bewegung (2)
- Bildanalyse (2)
- Biofilme (2)
- Biogeographie (2)
- Biologie (2)
- Biomarker (2)
- Biomaterialien (2)
- Biosensoren (2)
- Blatt (2)
- Calcineurin (2)
- Calcium-Imaging (2)
- Calliphora (2)
- Centrosome (2)
- Chloroplast (2)
- Chloroplasten (2)
- Cyanobacteria (2)
- Cytochrom c (2)
- DNA assembly (2)
- Differenzielle Genexpression (2)
- Disturbance (2)
- ENTH domain proteins (2)
- Early Starvation 1 (2)
- Einzelmolekülkraftspektroskopie (2)
- Elektrochemie (2)
- Enzym (2)
- European hare (2)
- Eutrophierung (2)
- Evolutionsbiologie (2)
- Feldhase (2)
- Fortbewegung (2)
- Fragmentierung (2)
- GABA (2)
- GC-MS (2)
- GPS (2)
- Gelatine (2)
- Gewässerökologie (2)
- HIV (2)
- Haptene (2)
- Heterosis (2)
- Hydrogel (2)
- Hydrogele (2)
- Hypoxie (2)
- Immobilisierung (2)
- Immunoassay (2)
- Insekt (2)
- Insekten (2)
- Interaktion (2)
- Introgression (2)
- Ionentransport (2)
- Kartoffel (2)
- Kernhülle (2)
- Koexpression (2)
- Korrelationsanalyse (2)
- Krankheitsökologie (2)
- Lamin (2)
- Landschaft der Angst (2)
- Lipide (2)
- Lipopolysaccharid (2)
- MHC (2)
- Mars (2)
- Massenspektrometrie (2)
- Medicago truncatula (2)
- Membranproteine (2)
- Metabolism (2)
- Metabolismus (2)
- Metabolite (2)
- Metabolomics (2)
- Metacommunity (2)
- Microcystin (2)
- Microtubules (2)
- Mikroorganismen (2)
- Mikrosatelliten (2)
- Mitochondrien (2)
- Mitose (2)
- Molekularbiologie (2)
- Molybdänkofaktor (2)
- Multiplex (2)
- Mykotoxine (2)
- Nahrungsnetz (2)
- Nahrungsnetze (2)
- Nanostruktur (2)
- Naturschutz (2)
- Netzwerke (2)
- Nitrat (2)
- Nostoc punctiforme (2)
- Obesity (2)
- Octopamin (2)
- PBPK (2)
- Paläoökologie (2)
- Parasit (2)
- Pathogen (2)
- Permafrost (2)
- Pflanze (2)
- Pflanzengemeinschaften (2)
- Pflanzenwachstum (2)
- Pflanzenökologie (2)
- Pharmakologie (2)
- Phosphat (2)
- Photosynthesis (2)
- Phylogenie (2)
- Phylogeographie (2)
- Phytoplankton (2)
- Plastid (2)
- Polyadenylierung (2)
- Polyelektrolyt-Multischichten (2)
- Polyethylenglykol (2)
- Polysaccharide (2)
- Promotor (2)
- Protein-Engineering (2)
- Proteinaggregation (2)
- Proteine (2)
- Proteomics (2)
- QTL (2)
- QTL mapping (2)
- RNA-seq (2)
- RT-PCR (2)
- Redoxreaktion (2)
- Regulation (2)
- Reproduktionserfolg (2)
- Riesenvesikel (2)
- Räuber-Beute (2)
- Salmonella (2)
- Savanne (2)
- Schwefel (2)
- Sequenzierung (2)
- Sequenzierung der nächsten Generation (2)
- Stickstoff (2)
- Stress (2)
- Störung (2)
- Systems Biology (2)
- Tomate (2)
- Trockenstress (2)
- V-ATPase (2)
- Vesikel (2)
- Wachstum (2)
- Weizen (2)
- Weißstorch (2)
- Zellkern (2)
- Zweizustandsmodell (2)
- Zytoskelett (2)
- actin (2)
- adhesion (2)
- agent-based model (2)
- animal personality (2)
- arbuscular mycorrhizal symbiosis (2)
- atomic force microscopy (2)
- autophagy (2)
- auxin (2)
- bacteria (2)
- biochemistry (2)
- biogene Amine (2)
- biomarker (2)
- biosensors (2)
- cell division (2)
- cell shape (2)
- cell signaling (2)
- cell-free protein synthesis (2)
- cellulose (2)
- cellulose synthase complex (2)
- chlamydomonas (2)
- chloroplasts (2)
- cockroach (2)
- coiled coil (2)
- colon cancer (2)
- constraint-based modeling (2)
- cytoskeleton (2)
- database (2)
- deep biosphere (2)
- degradation (2)
- diabetes (2)
- dictyostelium (2)
- differential gene expression (2)
- disease ecology (2)
- drought stress (2)
- drug release (2)
- enzymes (2)
- evolutionary biology (2)
- expansion microscopy (2)
- flowering (2)
- fluktuierendes Licht (2)
- functional diversity (2)
- galactolipids (2)
- gene (2)
- gene expression (2)
- genetic engineering (2)
- genetic screen (2)
- genetischer Screen (2)
- grassland (2)
- honey bee (2)
- honeybee (2)
- hydrogels (2)
- hypoxia (2)
- immobilization (2)
- immunoassay (2)
- individual-based model (2)
- insect (2)
- interaction (2)
- ion transport (2)
- lamin (2)
- landscape of fear (2)
- lipopolysaccharide (2)
- local adaptation (2)
- metabolische Netzwerke (2)
- metabolites (2)
- microbiology (2)
- microcystin (2)
- microfluidics (2)
- microtubules (2)
- mitochondria (2)
- molecular biology (2)
- mycotoxins (2)
- nachhaltige Landnutzung (2)
- nanostructure (2)
- natural products (2)
- networks (2)
- nuclear envelope (2)
- organ size (2)
- organisches Material (2)
- paleoecology (2)
- parallel beta-helix (2)
- pathway engineering (2)
- pectate lyase (2)
- pharmacology (2)
- phloem (2)
- phloem proteins (2)
- phosphate (2)
- phylogeny (2)
- phytoplankton (2)
- plankton (2)
- plant community (2)
- plant diversity (2)
- plant ecology (2)
- plant science (2)
- plants (2)
- plasticity (2)
- plastid transformation (2)
- point-of-care (2)
- polyadenylation (2)
- polyethylene glycol (2)
- predator-prey (2)
- protein engineering (2)
- receptor (2)
- redox (2)
- reductive glycine pathway (2)
- regulation (2)
- reproduction (2)
- reptiles (2)
- shoot apical meristem (2)
- single-molecule force spectroscopy (2)
- species coexistence (2)
- species richness (2)
- sucrose (2)
- sulfite oxidase (2)
- symbiosis (2)
- tailspike (2)
- tobacco (2)
- trait variation (2)
- transitory starch (2)
- tropical freshwater fish (2)
- two-state model (2)
- tyramine (2)
- ubiquitination (2)
- virus (2)
- weakly electric fish (2)
- xanthine dehydrogenase (2)
- zooplankton (2)
- "Omik"-Technologien (1)
- "Optimal annual routine"-Modell (1)
- (Xeno)Hormone (1)
- (xeno)hormones (1)
- 10-Formyltetrahydrofolat (1)
- 10-Formyltetrahydrofolate (1)
- 11beta-HSD1 (1)
- 13CO2 labeling (1)
- 2-oxoglutarat / FeII- abhängige Dioxygenases (1)
- 2-oxoglutarate /FeII-dependant dioxygenases (1)
- 26S-Proteasom-System-Abbau (1)
- 3-Phosphoglycerinsäure (1)
- 5,10-Methenyltetrahydrofolat (1)
- 5,10-Methenyltetrahydrofolate (1)
- 5,10-Methylenetetrahydrofolate (1)
- 5-Methoxycarbonylmethyl-2-Thiouridin (1)
- 5-Methylaminomethyl-2-Thiouridin (1)
- 5-Methyltetrahydrofolat (1)
- 5-Methyltetrahydrofolate (1)
- 5-methoxycarbonylmethyl-2-thiouridine (1)
- 5-methylaminomethyl-2-thiouridine (1)
- 60S maturation (1)
- 60S-Reifung (1)
- 7-Methylheptadecan (1)
- 7-methylheptadecane (1)
- ABA (1)
- ABC Transporter (1)
- ABC transporter (1)
- ABCB7 (1)
- AC Elektrokinetik (1)
- AC Elektroosmosis (1)
- AC electrokinetics (1)
- AC electroosmosis (1)
- ACD6 (1)
- ADP-Glukosepyrophosphorylase (1)
- AFLP (1)
- AIDS (1)
- ALOX15B (1)
- AMP (1)
- AMT (1)
- APX2 (1)
- ARMS (1)
- AT1 receptor / preeclampsia / AT1-AAB / neonatal rat cardiomyocytes / autoantibody / angiotensin II (1)
- AT1-Rezeptor / Präeklampsie / AT1-AAK / neonatale Rattenkardiomyozyten / Autoantikörper / Angiotensin II (1)
- ATP (1)
- ATPS (1)
- Abbau (1)
- Abszisinsäure (1)
- Acetobacteraceae (1)
- Acetyl-CoA carboxylase (1)
- Acetylcholinesterase (1)
- Acinonyx jubatus (1)
- Activity (1)
- Adaptation (1)
- Addax nasomaculatus (1)
- Adhäsionsproteine (1)
- Adiponectin (1)
- Adipositas (1)
- African weakly electric fish (1)
- Agent-based models (1)
- Aggressivität (1)
- Agrarlandschaft (1)
- Agroecology (1)
- Aktin (1)
- Aktin/Mikrotubuli (1)
- Aktinzytoskelett (1)
- Aktionsraum (1)
- Aktivitätsmessung (1)
- Alcaligenes eutrophus (1)
- Aldehyd (1)
- Aldehyd-oxidase (1)
- Allometrie (1)
- Altersabhängigkeit (1)
- Altitude (1)
- Alzheimer (1)
- Amaranthus retroflexus (1)
- Amblystegiaceae (1)
- Amerikanische Schabe (1)
- Aminosäuren (1)
- Ammonium (1)
- Ammoniumassimilation (1)
- Ammoniumtransporter (1)
- Amperometrie (1)
- Amphibians (1)
- Amphibien (1)
- Amsinckia (1)
- Amyloid beta (1)
- Angewandte Mikrobiologie (1)
- Angiogenese (1)
- Annamites (1)
- Anoxie (1)
- Anreicherungsmethoden (1)
- Anti-Diuron-Antikörper (1)
- Antibiotic alternatives (1)
- Antibiotic resistance (1)
- Antibiotika (1)
- Antibiotikaersatz (1)
- Antibodies (1)
- Antibody (1)
- Antikörpercharakterisierung (1)
- Antikörperproduktion (1)
- Antikörpervalidierung (1)
- Antilope (1)
- Apis mellifera (1)
- Apodemus (1)
- Apoptose (1)
- Aptamer (1)
- Aptamers (1)
- Apteryx (1)
- Apyrase (1)
- Aquifer (1)
- Arabidopsis thaliana cell size S-morph (1)
- Arbeitsteilung (1)
- Arbuskuläre Mykorrhiza (1)
- Arealverschiebungen (1)
- Argininbiosynthese (1)
- Array Hybridisierung (1)
- Arsen (1)
- Arsenic (1)
- Artengemeinschaft (1)
- Artenreichtum (1)
- Artenschutz (1)
- Artenzahl (1)
- Artverbreitungsmodelle (1)
- Arylcarbamate (1)
- Arylharnstoffe (1)
- Ascomycota (1)
- Ascorbat-Oxidase (1)
- Assemblierungsfaktor (1)
- Assoziation (1)
- AtAMT1.1 (1)
- AtAMT1.2 (1)
- AtAMT1.3 (1)
- AtAMT1.4 (1)
- AtAMT1.5 (1)
- AtDGK gene (1)
- AtDGK genes (1)
- Atrophin-1 (1)
- Auenreaktivierung (1)
- Aufnahme (1)
- Ausbreitungsverhalten (1)
- Auskreuzungsrate (1)
- Ausrichtung (1)
- Aussterben (1)
- Aussterbeschuld (1)
- Austausch zwischen zwei Spezies (1)
- Australia (1)
- Australien (1)
- Autophagie (1)
- Autotrophie (1)
- Auxin (1)
- Auxine (1)
- Auxotrophie (1)
- B lymphocytes (1)
- B-Lymphozyten (1)
- B. calyciflorus species complex (1)
- BESSY (1)
- BIA (1)
- BROAD LEAF1 (1)
- Bacteria (1)
- Bakterien Sensor (1)
- Bakteriophage T7 (1)
- Barley (1)
- Bastardbleichheit (1)
- Baumgrenze (1)
- Baumgrenzen-Dynamik (1)
- Baumsavanne (1)
- Bayes'sche Inferenz (1)
- Bayesian inference (1)
- Bead (1)
- Behaviour (1)
- Benzaldehyd (1)
- Beschleunigungsmessungen (1)
- Bestandsparameter (1)
- Bestäubung (1)
- Beta-Diversität (1)
- Beta-Zelle (1)
- Biene (1)
- Bioaktivierung (1)
- Bioelektrokatalytisches Recycling (1)
- Biogas (1)
- Biogene Amine (1)
- Biogenese (1)
- Biokatalyse (1)
- Biokatalytisches Recyc (1)
- Biomasse (1)
- Biomaterial (1)
- Biomembran (1)
- Biomolekülinteraktionen (1)
- Bioreaktor (1)
- Biosignaturen (1)
- Biosynthese (1)
- Biotechnologie (1)
- Biotoptypen (1)
- Bioökonomie (1)
- Bistabilität (1)
- Bisulfit Sequenzierung (1)
- Bittergeschmack (1)
- Bittergeschmacksrezeptor (1)
- Blattalterung (1)
- Blattbreite (1)
- Blattläuse (1)
- Blattmorphologie (1)
- Blaubock (1)
- Blaulicht (1)
- Blaulichtsensoren (1)
- Blue antelope (1)
- Blue-light sensors (1)
- Blühzeit (1)
- Blüte-Bestäuber-Interaktion (1)
- Blütenduft (1)
- Blütenökologie (1)
- Bodenmikrobiologie (1)
- Bombina bombina (1)
- Borna Disease Virus (1)
- Borna disease virus (1)
- Borrelia burgdorferi (1)
- Botanik (1)
- Boten-RNA (mRNA) (1)
- Brachfläche (1)
- Brachionus (1)
- Brassinosteriods (1)
- Brassinosteroide (1)
- Braunmoose (1)
- Breeding (1)
- Breitengrad (1)
- Brownification (1)
- Brut (1)
- Bryophyten (1)
- Bt maize (1)
- Bt-Mais (1)
- Buchfink (1)
- Budozone (1)
- C1 assimilation (1)
- C1-Assimilation (1)
- C4 (1)
- CBD (1)
- CD95 (1)
- CDF (1)
- CDK5RAP2 (1)
- CEA (1)
- CED (1)
- CESA Komplex (1)
- CHO-THF, CH-THF, CH2-THF und CH3-THF (1)
- CHO-THF, CH-THF, CH2-THF, and CH3-THF (1)
- CNL1 (1)
- CO2 degassing (1)
- CO2-Entgasung (1)
- CP75 (1)
- CRISPR/Cas9 (1)
- CaM4 (1)
- Calcineurin-Inhibitoren (1)
- Calcium (1)
- Calorimetry (1)
- Calvin cycle (1)
- Calvinzyklus (1)
- Campylomormyrus (1)
- Canopy parameters (1)
- Capsella (1)
- Carbon Cycling (1)
- Carbon concentrating mechanism (1)
- Carbon cycling (1)
- Carboxynitrofluorenon (1)
- Carboxysomen (1)
- Carry-over-Effekte (1)
- Cell cycle (1)
- Cellulose-Synthese-Complex (1)
- Central America (1)
- Central Europe (1)
- Centromere (1)
- Centromeres (1)
- Cep192 (1)
- Chaffinch (1)
- Chelonia mydas (1)
- Chemostatexperimente (1)
- Chemotaxis (1)
- Chenopodium album (1)
- Chicken Repeat (1)
- Chiroptera (1)
- Chlorella vulgaris (1)
- Chlorophyll (1)
- Chloroplast gene expression (1)
- Chloroplast transformation (1)
- Chloroplasten-Genexpression (1)
- Chloroplastentransformation (1)
- Chromatin-Immunopräzipitation (1)
- Chukotka vegetation (1)
- Ciliaten (1)
- Clathrin-bedeckte Vesikel (1)
- Climate (1)
- Climate change (1)
- Clostridium difficile (1)
- Co-Evolution (1)
- Co-Transfektion (1)
- Codierungssequenz (1)
- Codon Usage (1)
- Coexpression (1)
- Coiled Coil (1)
- Coiled coils (1)
- Cokultur (1)
- Cold acclimation (1)
- Colonkrebs (1)
- Columella (1)
- Composite (1)
- Computational Biology (1)
- Constraint-basierte Modellierung (1)
- Copolymere (1)
- Corynephorus canescens (1)
- Costamer (1)
- Covalent imprinting (1)
- Cre Rekombinase (1)
- Cre recombinase (1)
- Cupriavidus necator (1)
- Cyanobakterien-Biomarker (1)
- Cyclosporin A (1)
- Cylindrospermopsis raciborskii (1)
- Cytochome c (1)
- Cytosin-Methylierung (1)
- Cytosolische Translation in Pflanzen (1)
- DEK1 (1)
- DGD1 (1)
- DISC (1)
- DNA Ejektion (1)
- DNA Methylation (1)
- DNA ejection (1)
- DNA metabarcoding (1)
- DNA vaccine (1)
- DNA-Aptamer (1)
- DNA-Chip (1)
- DNA-Lipid-Wechselwirkung (1)
- DNA-Vakzinierung (1)
- DNA-lipid-interaction (1)
- DNS (1)
- DNS Assemblierung (1)
- DNS-Chip (1)
- DOC (1)
- DOF Transkriptionsfaktoren (1)
- DOF transcription factors (1)
- DON (1)
- DPE2 (1)
- DRB Evolution (1)
- DRB evolution (1)
- DRYM (1)
- DSS-Colitis (1)
- Darmkrebs (1)
- Datenanalyse und Statistik (1)
- Datenintegration (1)
- Datura stramonium (1)
- Dauerfrostboden (1)
- De novo Assemblierung (1)
- Deakklimatisierung (1)
- Degradom (1)
- Deichrückverlegung (1)
- Delomys (1)
- Derivatisierung (1)
- Dermochelys coriacea (1)
- Design Research (1)
- Detektionssystem (1)
- Deutschland (1)
- Development (1)
- Diacylglycerol (1)
- Diacylglycerol-Kinasen (1)
- Diagnostik (1)
- Dialel (1)
- Dichteabhängigkeit (1)
- Diffusion (1)
- Disproportionating Enzyme (1)
- Disproportionierungsenzym (1)
- Dissertation (1)
- Dissoziation (1)
- Diuron (1)
- Diversity-Productivity relationship (1)
- Diversitäts-Produktivitäts-Beziehung (1)
- Diätintervention (1)
- Doping (1)
- Dreischluchten-Stausee (1)
- Dreizustandsmodell (1)
- Drosophila (1)
- Drought tolerance (1)
- Durchflusszytometrie (1)
- Durchfluß-Biochip-Scanner (1)
- Dynamik (1)
- E-cadherin (1)
- E3-Ubiquitin Ligasen (1)
- E3-ubiquitin ligases (1)
- EGFP (1)
- ENTH-Domänen Proteine (1)
- ENTH-Domänenproteine (1)
- ETV (1)
- Early starvation protein (1)
- East Africa (1)
- Ecosystem development (1)
- Ecotoxicology (1)
- Effekt (1)
- Ein Kohlenstoff (1)
- Einschätzung der Diffusion (1)
- Einwanderungskredit (1)
- Einzelbasenaustausch (1)
- Einzelmolekül-Kraftspektroskopie (1)
- Einzelzell-Analyse (1)
- Einzelzell-Sequenzierung (1)
- Einzelzellanalytik (1)
- Einzelzellbewegung (1)
- Einzelzellen (1)
- Eisen (1)
- Eisen-Schwefel-Cluster (1)
- El Nino Southern Oscillation (1)
- El Niño/Southern Oscillation-Phänomen (1)
- El`gygytgyn Kratersee (1)
- Elastizitätsmodul (1)
- Electrochemistry (1)
- Elektrische Entladung (1)
- Elektrische Fische (1)
- Elektronenmikroskopie (1)
- El’gygytgyn Crater Lake (1)
- Emulsionen (1)
- Endophyten (1)
- Energetik (1)
- Energiebudget (1)
- Energiemangel (1)
- Entzündung (1)
- Environmental Metabolomics (1)
- Enzymadsorption (1)
- Enzyme adsorption (1)
- Enzyme kinetics (1)
- Enzymelektrode ; Monophenolmonooxygenase (1)
- Enzymmodelle (1)
- Ephrin (1)
- Epidemic (1)
- Epidemics (1)
- Epidemie (1)
- Epidemien (1)
- Epigenetics (1)
- Epigenom Editierung (1)
- Epiphyten (1)
- Epistase (1)
- Epistasis (1)
- Epithelien (1)
- Epitope mapping (1)
- Epitopmapping (1)
- Epitopvorhersage (1)
- Erbe (1)
- Erdbeben (1)
- Erhaltungszucht (1)
- Erigeron annuus (1)
- Erigeron canadensis (1)
- Ernte (1)
- Ernte von Wildebeständen (1)
- Ernährungsgewohnheiten (1)
- Ernährungszustand (1)
- Erweitertes Fachwissen für den schulischen Kontext (1)
- Erythropoese (1)
- Eschericha coli (1)
- Essentialität (1)
- Essigsäurebakterien (1)
- Etablierung (1)
- Eukaryoten (1)
- European bats (1)
- European corn borer (1)
- Europäische Fledermausarten (1)
- Evolutionsgenetik (1)
- Evolutionsrunde (1)
- ExPEC (1)
- Expansions-Mikroskopie (1)
- Expression (1)
- Extinktionsrisko (1)
- Extravasation-rate limited Gewebemodelle (1)
- Extrazelluläre Matrix (1)
- F-box (1)
- F. oxysporum (1)
- FLC (1)
- FLOWERING LOCUS C (1)
- FRAP (1)
- Fachwissen (1)
- Faltung (1)
- Feature Engineering (1)
- Feldberger Seenlandschaft ; Agrarlandschaft ; Brache ; Samenpflanzen ; Bestäuber ; Artenreichtum (1)
- Feldmaus (1)
- Ferrocen (1)
- Festkörper NMR Spektroskopie (1)
- Fettleibigkeit (1)
- Feuer (1)
- Fibroblasten (1)
- Filamente (1)
- Fis (1)
- Fisch (1)
- Fitness (1)
- Flachseen (1)
- Flagella (1)
- Flagellen (1)
- Flavonoid-Metabolismus (1)
- Fledermäuse (1)
- Fließsystem (1)
- Florigen (1)
- Fluorescence Quenching Immunoassay (1)
- Fluorescence quenching immunoassay (1)
- Fluoreszeinisothiocyanat (1)
- Fluoreszenz-in-situ-Hybridisierung (1)
- Fluoreszenzfluktuationsspektroskopie (1)
- Fluoreszenzkorrelationspektroskopie (1)
- Fluoreszenzmarkierung (1)
- Fokalkontakt (1)
- Food Web (1)
- Foraging (1)
- Formaldehyd-Assimilierung (1)
- Formgedächtnispolymere (1)
- Formiat (1)
- Fortpflanzung (1)
- Fotoschalter (1)
- Fragmentation (1)
- Fragmente (1)
- Frucht (1)
- Fruchtknoten (1)
- Fructose (1)
- Fructosyl valine (1)
- FtsZ (1)
- FtsZ ring assemby (1)
- FtsZ-Ringbildung (1)
- Fungal endophyte (1)
- Funktionelle Diversität (1)
- Fusarium (1)
- Futtersuchverhalten (1)
- Förster Resonanz Energie Transfer (FRET) (1)
- Förster resonance energy transfer (FRET) (1)
- G protein-coupled estrogen receptor (1)
- G protein-gekoppelter Östrogen Rezeptor (1)
- G-Protein-gekoppelte-Rezeptoren (1)
- G-protein-coupled receptors (1)
- G-protein-coupled-receptors (1)
- G-quartettes (1)
- GC-TOF-MS (1)
- GED cycle (1)
- GED-Zyklus (1)
- GPCRs (1)
- GPI (1)
- GTPase (1)
- GUV (1)
- GUVs (1)
- GWAS (1)
- Galacturonsäure (1)
- Galaktolipide (1)
- Gehirn (1)
- Gelatin (1)
- Gelenkbeweglichkeit (1)
- Gemeinschaftsgarten-Experiment (1)
- Gen (1)
- Gen-Koexpression (1)
- Gencluster-Aktivierung (1)
- Gene co-expression (1)
- Gene expression profiling (1)
- Genetic rescue (1)
- Genetic transformation (1)
- Genetische Rettung (1)
- Genfamilie (1)
- Genom-Scan (1)
- Genomic Mining (1)
- Genomics (1)
- Genotypisierung (1)
- Genregulation (1)
- Gentechnik (1)
- Gentechnologie (1)
- Gentherapie (1)
- Gentransfer (1)
- Geoinformationssystem (1)
- Germany (1)
- Gerste (1)
- Gerüste aus Fasergeflecht (1)
- Gesangsaktivität (1)
- Gesangsangleich (1)
- Gesangsdialekte (1)
- Gesangslernen (1)
- Geschmackswahrnehmung (1)
- Geschwindigkeit (1)
- Gewebsverteilung (1)
- Gewässer (1)
- Giant Vesicles (1)
- Giant unilamellar vesicles (1)
- Glanzstreifen (1)
- Glasfaser (1)
- Globaler Wandel (1)
- Globalwandel (1)
- Glucan water dikinase (1)
- Glucan-Wasser-Dikinase (1)
- Glucolipotoxizität (1)
- Glucosedehydrogenase (1)
- Glutathionperoxidase-2 GPx2 (1)
- Glycated hemoglobin (1)
- Glycated hemoglobin; HbA1c; diabetes; biosensor; immunosensor; enzyme sensor; electrochemical; amperometric; immunoassay; diagnostics; haptoglobin; im (1)
- Glycin-Decarboxylase-Komplex (=GCV) (1)
- Glycin-Spaltsystem (1)
- Glycin-Synthase-Komplex (Umkehrung von GCV) (1)
- Glycosylierung (1)
- Glykiertes Hämoglobin; HbA1c; Diabetes; Biosensor; Immunosensor; Enzymsensor; amperometrisch; elektrochemisch; Immunoassay; Diagnostik; Haptoglobin; (1)
- Glykogen (1)
- Graphtheorie (1)
- Grasland (1)
- Griffithsin (1)
- Growth (1)
- Growth signaling (1)
- Grundwasser (1)
- Grünland (1)
- Gute-Gene (1)
- H16 (1)
- H2S biosynthesis (1)
- H2S-Biosynthese (1)
- H3K27me3 Methylation (1)
- H3K4me (1)
- H3K9ac (1)
- HAC1 (1)
- HDA (1)
- HIV Erkrankung (1)
- HMA (1)
- HPµF (1)
- HS transcriptional memory (1)
- HS-Transkriptionsgedächtnis (1)
- HSE (1)
- HSF (1)
- HSFA2 (1)
- HUVEC (1)
- Handkraft (1)
- Hantaviren (1)
- Hantavirus (1)
- Haupthistokompatibilitätskomplex (1)
- HbA1c (1)
- Heat stress memory, Heat shock factors, Mediator subunits, MED23, MED32, Arabidopsis thaliana (1)
- Hefe (1)
- Helix <beta-> (1)
- Henlesche Schleife (1)
- HepG2 hepatocytes (1)
- HepG2-Zellen (1)
- Herbizide (1)
- Herzentwicklung (1)
- Herzklappe (1)
- Herzmuskelkrankheit (1)
- Heubacillus ; Pectat-Lyase ; Helix <beta-> (1)
- High Power LED Array (1)
- Hippotragus leucophaeus (1)
- Histidin-Metall Koordination (1)
- Histon Methylierung (1)
- Histone Modification (1)
- Hitzeschock-Transkriptionsfaktor (1)
- Hitzestress (1)
- Hitzestress-Gedächtnis (1)
- Hochdurchsatzsequenzierung (1)
- Hochleistungs-LED-Array (1)
- Holozän (1)
- Homogeneous immunoassay (1)
- Homoger Immunoassay (1)
- HopZ1a (1)
- Hordeum vulgare (1)
- Huftiere (1)
- Huntington (1)
- Hybridisierung (1)
- Hybridom (1)
- Hybridomtechnik (1)
- Hybridzerfall (1)
- Hydrogenomonas eutrophus (1)
- Hydrophilie (1)
- Hydroxyapatit (1)
- Hydroxyapatite (1)
- Hyena (1)
- Hyperakkumulation (1)
- Hyperoxide (1)
- Hyäne (1)
- Hämatopoetische Stammzellen (1)
- Hämatopoiese (1)
- Hämoglobin A / Bestimmung / Biosensor / Amperometrie (1)
- Hämolyse (1)
- Höhe (1)
- Hülsenfrüchtler (1)
- IAV particles (1)
- IAV-Partikel (1)
- IBD (1)
- IC (1)
- ICP OES (1)
- IDPs (1)
- INCURVATA11 (1)
- INDETERMINATE DOMAIN protein (1)
- INDETERMINATE DOMAIN-Protein (1)
- IP3 (1)
- IP3-Rezeptor (1)
- IP3-receptor (1)
- IR laser (1)
- IRF3 (1)
- Identifizierung (1)
- Immunfluoreszenz (1)
- Immunoassay; GDH-biosensor; Phenolische Substanzen; Vor-Ort-Analytik; FIA; ß-Galactosidase; Abwasseranalytik (1)
- Immunogene Proteine (1)
- Immunogenic Proteins (1)
- Immunologie (1)
- Immunscreening (1)
- Immunsystem (1)
- Importin (1)
- In vitro transcription technology (1)
- In vitro-Immunisierung (1)
- In-vitro-Transkriptionstechnologie (1)
- Individuen-basierende Modelle (1)
- Influenza A Viren (1)
- Influenza A Virus (1)
- Influenza A virus (1)
- Influenza-A-Virus (1)
- Inosite (1)
- Insektizide (1)
- Integrative Analyse (1)
- Integrative analysis (1)
- Interactors (1)
- Interaktions Netzwerk (1)
- Interaktionsstudie (1)
- Interaktoren (1)
- Interferon <beta-> (1)
- Internalin B (1)
- Internalin J (1)
- Intraspezifische Variation (1)
- Introgression Lines (1)
- Invertase (1)
- Inverted emulsion-based method (1)
- Ionenmobilitätsspektrometrie (IMS) (1)
- Isoenzyme (1)
- Isoformen (1)
- JUB1 (1)
- JUMONJI (1)
- Jaguar (1)
- Kalorimetrie (1)
- Kalzit (1)
- Kanalisierung (1)
- Kapillarelektrophorese (1)
- Kartoffelknolle (1)
- Kaskadeneffekte (1)
- Katalyse (1)
- Katze (1)
- Keratinozyten (1)
- Kernlokalisierungssignal (1)
- Kinesin (1)
- Klassifikation der Landbedeckung (1)
- Kleinsäuger (1)
- Klick-Chemie (1)
- Klima (1)
- Knock in Mäuse (1)
- Koexistenz Mechanismen (1)
- Koexistenz unter wechselnden Bedingungen (1)
- Koexistenz von Arten (1)
- Koexpression Netzwerk Analysen (1)
- Kohlenhydrat Erkennung (1)
- Kohlenhydrat-Protein Interaction (1)
- Kohlenhydrat-Protein-Wechselwirkung (1)
- Kohlenhydrate (1)
- Kohlenstoff (1)
- Kohlenstoff-Konzentrationsmechanismus (1)
- Kohlenstofffixerung (1)
- Kohlenstoffisotope (1)
- Kohlenstoffmetabolismus (1)
- Kohlenstoffspeicherung (1)
- Kokain (1)
- Kolonialität (1)
- Kombinationstherapie (1)
- Kompartiment-Modelle (1)
- Komplexauge (1)
- Komposite (1)
- Kompromiss (1)
- Konfokale Mikroskopie (1)
- Konkurrenz (1)
- Konnektivität (1)
- Konsequenzen von Fang und Besenderung (1)
- Kontraception (1)
- Korrelation (1)
- Korrosion (1)
- Krankheitsausbruch (1)
- Krankheitserreger (1)
- Krebs (1)
- Krebsbiomarker (1)
- Krebserkennung (1)
- Krebstherapie (1)
- Kälteakklimatisierung (1)
- Kältestress (1)
- Körperbautyp (1)
- Körperfett (1)
- Körperzusammensetzung (1)
- L-morph (1)
- LAMP (1)
- LASSO (1)
- LAVESI (1)
- LC-FT-MS (1)
- LC-OCD-OND (1)
- LCM (1)
- LEA (1)
- LEUNIG LEUNIG_HOMOLOG SEUSS SEUSS-LIKEs Arabidopsis embryogenesis WOX2-module HD-ZIPIII (1)
- LHCII (1)
- LOC (1)
- Lab on chip (1)
- Lab-on-a-chip (1)
- Lactuca serriola (1)
- Lafora disease (1)
- Lake TaiHu (1)
- Land Reform (1)
- Landnutzung (1)
- Landnutzungshistorie (1)
- Landschaftsanalyse (1)
- Landschaftsheterogenität (1)
- Langzeitaustrocknung (1)
- Langzeitveränderung (1)
- Larix (1)
- Larix cajanderi (1)
- Leaf senescence (1)
- Leaf trichomes (1)
- Lebensmittelanalytik (1)
- Lebensraumnutzung (1)
- Lebenszyklustheorie (1)
- Leghämoglobin (1)
- Legionella (1)
- Legionellen (1)
- Leguminosenlektin (1)
- Len (1)
- Lernen und Gedächtnis (1)
- Leucine-Rich Repeat (1)
- Leukocyte Receptor Complex LRC KIR ILT FCAR Immunglobulin Evolution Immunsystem SNP HRCA (1)
- Leukocyte Receptor Complex LRC KIR ILT FCAR immunoglobulin evolution SNP HRCA (1)
- Licht (1)
- Licht-induzierte (1)
- Lichtanpassung (1)
- Lichtverschmutzung (1)
- Like-Early Starvation 1 (1)
- Like-Early starvation protein (1)
- Lipid Synthese (1)
- Lipid synthesis (1)
- Lipide / Doppelschicht (1)
- Lipids (1)
- Lipidsynthese (1)
- Lipophagie (1)
- Lipopolysaccharide (1)
- Lipoxygenase (1)
- Litoral (1)
- Local adaptation (1)
- Lotus japonicus (1)
- Lysosom (1)
- Lärche (1)
- M-Bandenmodell (1)
- M-band model (1)
- M1-Lipide (1)
- M1-M1 interaction (1)
- M1-M1-Interaktion (1)
- M1-lipids (1)
- MADS (1)
- MAP kinase (1)
- MAPK (1)
- MC38 (1)
- MEX1 (1)
- MHC Klasse II (1)
- MHC polymorphism (1)
- MIP sensor (1)
- MSAP (1)
- MTP (1)
- MTP1 (1)
- MTP2 (1)
- MTP3 (1)
- MUC1 (1)
- MVA (1)
- Mahd (1)
- Mais (1)
- Maiszünsler (1)
- Maize (1)
- Makrophagen-Aktivierung (1)
- Makrophyten (1)
- Maltodextrin (1)
- Mantodea (1)
- Marsanaloge Regolithe (1)
- Martian regolith analogs (1)
- Maschinelles-Lernen (1)
- Matrix (1)
- Maus Aldehydoxidase1 (1)
- Maßstabsabhängigkeit (1)
- Mechanistic models (1)
- Mechanistische Modelle (1)
- Mechanobiologie (1)
- Mechanosensation (1)
- Medicago (1)
- Mehrkomponentenanalyse (1)
- Membran (1)
- Membranbindung (1)
- Membrandeformation (1)
- Membrane deformation (1)
- Membrane protein (1)
- Membranfluidität (1)
- Menschenobhut (1)
- Merkmalsvariation (1)
- Merkmalsvielfalt (1)
- Mesophyll (1)
- Messenger RNA (mRNA) (1)
- Messenger-RNS (1)
- Metabolic Engineering (1)
- Metabolic Modeling (1)
- Metabolische Netzwerke (1)
- Metabolismus von Medikamenten (1)
- Metabolite Profiling (1)
- Metaboliten (1)
- Metabolitprofil (1)
- Metabolom (1)
- Metabolome (1)
- Metagemeinschaft (1)
- Metagemeinschaften (1)
- Metallkation (1)
- Methan (1)
- Methane (1)
- Methanemission (1)
- Methanogene (1)
- Methanogene Archaeen (1)
- Methanotrophe (1)
- Methylotrophie (1)
- Metrik-Index (1)
- Microarrays (1)
- Microbial communities (1)
- Microbiology (1)
- Microcystis (1)
- Microorganisms (1)
- Microsatellite (1)
- Microscale Thermophoresis (MST) (1)
- Microscopy (1)
- Microtus (1)
- Microtus arvalis (1)
- Microviridin (1)
- Mikroalgen (1)
- Mikrobielle Gemeinschaften (1)
- Mikrochip (1)
- Mikrogel (1)
- Mikroheizung (1)
- Mikroplastikpartikel (1)
- Mikroskop (1)
- Mikrostrukturierung (1)
- Mikroviskosität (1)
- Mining lakes (1)
- Mitosis (1)
- Mittelamerika (1)
- Mitteleuropa (1)
- Moco biosynthesis (1)
- Moco-Biosynthese (1)
- Modeling (1)
- Modell (1)
- Modelle der Nahrungsnetze (1)
- Modified Vaccinia Virus Ankara (1)
- Molecular modeling (1)
- Molecular profile data (1)
- Molekular-dynamik (1)
- Molekulardynamik-Simulation (1)
- Molekulare Modellierung (1)
- Molekulare Profildaten (1)
- Molekülmodelle (1)
- Molybdenum Cofaktor (1)
- Molybdenum cofactor biosynthetic (1)
- Molybdoflavoenzyme (1)
- Molybdän (1)
- Monitoring (1)
- Monoschicht (1)
- Moorsukzession (1)
- Moos-Mikroben-Interaktion (1)
- Moos-assoziierte Methanoxidation (1)
- Moos-assoziierte Methanproduktion (1)
- Morphologie <Biologie> (1)
- Mortalität (1)
- Mucin (1)
- Multilayers (1)
- Multiparameter (1)
- Multiple-Sklerose (1)
- Multiplex PCR (1)
- Multivalenz (1)
- Muscle LIM Protein (MLP) (1)
- Muskel (1)
- Muskel-Sehnen-Verbindung (1)
- Muskel-Skelett-System / Bewegungsapparat (1)
- Mutagenität (1)
- Mutation (1)
- Mutations (1)
- Muzin (1)
- Mycorrhiza (1)
- Mycorrhizal symbiosis (1)
- Mykorrhiza (1)
- Mykorrhizasymbiose (1)
- Myodus glareolus (1)
- Myofibrille (1)
- NCI3 (1)
- NE81 (1)
- NF-kappaB (1)
- NFAT (1)
- NGS (1)
- NMR (1)
- NZO (1)
- Nachhaltigkeit (1)
- Nahrungsmittelallergie (1)
- Nahrungssuche (1)
- Nanoelektroden (1)
- Nanopartikel (1)
- Natural Products (1)
- Naturschutzgenetik (1)
- Neisseria gonorrhoeae (1)
- Neisseria meningitidis (1)
- Nekrose (1)
- Nektar (1)
- Nettoproduktion (1)
- Neu-Delhi Metallo-Beta-Laktamase 1 (NDM-1) (1)
- Neuritenwachstum (1)
- Neuroendocrine tumors (1)
- New Delhi metallo-β-lactamase 1 (NDM-1) (1)
- Next generation sequencing (1)
- Nicht-Ziel-Arthropoden (1)
- Nicht-Zielorganismen (1)
- Nichtgleichgewichts-Dynamiken (1)
- Nicotiana tabacum (1)
- Niere (1)
- Nilhechte <Familie> (1)
- Nischen-Aufteilung (1)
- Nitrate (1)
- Nitrogen (1)
- Noctilio albiventris (1)
- Nodulin (1)
- Nucleus (1)
- Nukleinsäuren (1)
- Nukleosidase (1)
- Nullmodell (1)
- Nützlinge (1)
- O-Antigen (1)
- O-antigen (1)
- Oberflächenfunktionalisierung (1)
- Oberflächenladung (1)
- Oberflächenplasmonenresonanzspektroskopie (SPR-Spektroskopie) (1)
- Oberflächentemperatur (1)
- Oderbruch (1)
- Oligomer (1)
- OmpG (1)
- On Chip PCR (1)
- On-Chip-PCR (1)
- One-carbon (1)
- Ontogenie (1)
- Open Access (1)
- Open Source (1)
- Operon (1)
- Optimality (1)
- Optimalität (1)
- Optimierung von Biosynthesewegen (1)
- Optogenetik (1)
- Ordnung der Partikel auf der Oberfläche (1)
- Organgröße (1)
- Organischer Bodenkohlenstoff (1)
- Organophosphate (1)
- Oryza sativa (1)
- Ostafrika (1)
- Osteogenese (1)
- Ostrinia nubilalis (1)
- Oxidoreduktase (1)
- Ozeanversauerung (1)
- P-Typ ATPase (1)
- P22 Tailspikeprotein (1)
- P22 tailspike protein (1)
- PBS1 (1)
- PEEU (1)
- PGR5 (1)
- PLP-Walker A-overlap (1)
- PLP-Walker A-Überlagerung (1)
- PNIPAM (1)
- POC (1)
- POCT (1)
- PVA (population viability analysis) (1)
- Paarbindung (1)
- Paarungssystem (1)
- PacBio IsoSeq (1)
- Pace-of-Life Syndrom (1)
- Palmitat (1)
- Palmöl (1)
- Paläovegetation (1)
- Panthera Pardus (1)
- Panthera pardus (1)
- Pantoea stewartii (1)
- Papageien (1)
- Paramutation (1)
- Parasite (1)
- Parasiten (1)
- Parasites (1)
- Parasitierung (1)
- Parkinson's disease (1)
- Parkinson-Krankheit (1)
- Parrots (1)
- Passeriformes (1)
- Pathogenantwort (1)
- Pathogenerkennung (1)
- Pathway Abbildung (1)
- Pathwaysuche (1)
- Pektat-Lyase (1)
- Pektatlyase (1)
- Pektin (1)
- Pektinase (1)
- Pektine (1)
- Pektinsäure (1)
- Pelletbildung (1)
- Peptide (1)
- Peptidyl-Prolyl-cis-trans Isomerisierung (1)
- Performance (1)
- Periphyton (1)
- Periplaneta (1)
- Periplaneta americana (1)
- Periplasma (1)
- Permafrostdegradation (1)
- Peroxid (1)
- Peroxidase (1)
- Peroxide (1)
- Pestizide (1)
- Pflanze-Pilz-Interaktionen (1)
- Pflanzen-Mikroben-Interaktionen (1)
- Pflanzenanpassung (1)
- Pflanzendiversitaet (1)
- Pflanzenentwicklung (1)
- Pflanzenernährung (1)
- Pflanzenforschung (1)
- Pflanzengemeinschaft (1)
- Pflanzenhormon (1)
- Pflanzenwissenschaften (1)
- Pflanzenzellen (1)
- Pflasterzelle (1)
- Pfotenödem Mausmodell (1)
- PhIP (1)
- Phage Display (1)
- Phage HK620 (1)
- Phage lysins (1)
- Phagen Infektion (1)
- Phagenlysine (1)
- Pharmakodynamik (1)
- Pharmakokinetik (1)
- Phenanthrolindion (1)
- Phenol (1)
- Phenotype (1)
- Phenotyping (1)
- Phloem (1)
- Phloemproteine (1)
- Phosphat akkumulierende Organismen (1)
- Phosphatase (1)
- Phosphatidsäure (1)
- Phosphoglucan water dikinase (1)
- Phosphoglucan-Wasser-Dikinase (1)
- Phospholipide (1)
- Phosphoproteomik (1)
- Phosphorylation process (1)
- Phosphorylierungsprozess (1)
- Photoelektrchemischer Sensor (1)
- Photokatalyse (1)
- Photorespiration (1)
- Photosystem I (1)
- Photosäure (1)
- Phylogenese (1)
- Phylogeni (1)
- Phylogeny (1)
- Physical Network (1)
- Physikalische Quervernetzung (1)
- Phytol (1)
- Phytoplankton und Zooplankton (1)
- Phytoplanktonpopulationen (1)
- Phänologie (1)
- Phänotyp (1)
- Phänotypisierung (1)
- Pichia pastoris (1)
- Pilz-Endophyten (1)
- Pilze (1)
- Plankton (1)
- Planktonnahrungsnetz (1)
- Plant cytosolic translation (1)
- Plant development (1)
- Plant growth (1)
- Plant hormones (1)
- Plantago major (1)
- Plants (1)
- Plasma membrane (1)
- Plasmamembran (1)
- Plastizität (1)
- Plastome-evolution (1)
- Plastomevolution (1)
- Pleistozän (1)
- Pollen (1)
- Poly(A)-Polymerasen (1)
- Poly-N-Isopropylacrylamid (1)
- Polyandrie (1)
- Polyelektrolyt (1)
- Polyethylen (1)
- Polymer-Netzwerke (1)
- Polymerase-Kettenreaktion (1)
- Polymermembranen (1)
- Polyneuropathie (1)
- Polysaccharides (1)
- Ponsin (1)
- Populationsbiologie (1)
- Populationsgefährdungsanalyse (1)
- Populationsgenetik (1)
- Populationskonnektivität (1)
- Populationspersistenz (1)
- Populationsstruktur (1)
- Populationsökologie (1)
- Porphyrin (1)
- Predation (1)
- Primärproduktion (1)
- Primärproduzenten (1)
- Professionswissen (1)
- Profilmessung (1)
- Profilmethode (1)
- Promoter (1)
- Promotoren (1)
- Prostatakrebs (1)
- Proteaceae (1)
- Proteaceen (1)
- Protease-Inhibitoren (1)
- Proteasomaler Abbau (1)
- Protein Spektroelektrochemie (1)
- Protein complex assembly (1)
- Protein spectroelectrochemistry (1)
- Protein synthesis (1)
- Protein-Aptamer Interaktion (1)
- Protein-Kohlenhydrat Interaktionen (1)
- Protein-Kohlenhydrat-Interaktion (1)
- Protein-Metall-Wechselwirkung (1)
- Protein-Protein-Wechselwirkung (1)
- Proteinbindung (1)
- Proteindegradierung (1)
- Proteindomänen (1)
- Proteinfaltungstest (1)
- Proteinhandel (1)
- Proteinkinase (1)
- Proteinkinase A (1)
- Proteinkomplexassemblierung (1)
- Proteinmissfaltung (1)
- Proteinmodifizierung (1)
- Proteinmultimerisierung (1)
- Proteinphosphatasen (1)
- Proteinphosphorylation (1)
- Proteinphosphorylierung (1)
- Proteinrekonstitution (1)
- Proteinsekretion (1)
- Proteinspiegel regulieren (1)
- Proteinstruktur (1)
- Proteinsynthese (1)
- Prozessierung (1)
- Prozessregenerierung (1)
- Prädation (1)
- Pseudomonas syringae (1)
- Punicalagin (1)
- Pyrophosphat (1)
- QSP (1)
- QTL Analyse (1)
- Quantum Dots (1)
- Quergestreifte Muskulatur (1)
- R (Programmiersprache) (1)
- R.c. Xanthindehydrogenase (1)
- RCAN1 (1)
- RING/U-box E3 (1)
- RNA (1)
- RNA-Sequenzierung (1)
- RNA-sequencing (1)
- RNAi (1)
- ROS (1)
- Radiokarbon (1)
- Rahmenübereinkommen der Vereinten Nationen über Klimaänderungen (1)
- Ralstonia eutropha (1)
- Raman Spektroskopie (1)
- Raman spectroscopy (1)
- Randomisierung (1)
- Rasterkraftmikroskop (1)
- Reaktionsgeschwindigkeit (1)
- Real Time PCR (1)
- Rechtsgängige parallele beta-Helix (1)
- Recombinant Antibodies (1)
- Recyclingsystem (1)
- Redox (1)
- Redoxine (1)
- Redoxsystem (1)
- Regeneratin (1)
- Regeneration (1)
- Regulationsweg (1)
- Regulatorische Gene (1)
- Regulierung der Genexpression (1)
- Rekombinante Antikörper (1)
- Remorin (1)
- Reproduktion (1)
- Reproduktivität (1)
- Reptilien (1)
- Resilience (1)
- Resilienz (1)
- Resistenzmechanismen (1)
- Respiration (1)
- Respiratorisches Synzytial-Virus (1)
- Retrotransposon (1)
- Reverse Transcription (1)
- Reverse Transkription (1)
- Rhabdomerverdrehung (1)
- Rhamnose (1)
- Rheologie (1)
- Rhizobium (1)
- Rhizophagus irregularis (1)
- Rhodamin B (1)
- Rhodamine B (1)
- Rhodanese (1)
- Rhodobacter capsulatus (1)
- RiPP (1)
- Ribosom (1)
- Ribosomal protein heterogeneity (1)
- Ribosomal protein substoichiometry (1)
- Ribosomale Protein Substöchiometrie (1)
- Ribosomale Proteinheterogenität (1)
- Ribosome biogenesis (1)
- Ribosome profiling (1)
- Ribosome specialization (1)
- Ribosomen-Biogenese (1)
- Ribosomen-Spezialisierung (1)
- Ribulose-Monophosphat-Weg (1)
- Risikoabbildung (1)
- Risikoabschätzung (1)
- Rotatorien (1)
- RpoS (1)
- Rstats (1)
- RuBisCO (1)
- RubisCO (1)
- Rubisco (1)
- Ruhezentrum (1)
- Russia (1)
- Russland (1)
- Räuber-Beute Beziehungen (1)
- Räuber-Beute Dynamiken (1)
- Rötelmaus (1)
- Rückkreuzungsinzuchtlinie (BIL) (1)
- S-morph (1)
- SAP (1)
- SCF complex (1)
- SJL (1)
- SNP (1)
- SORLA (1)
- SS4 (1)
- STERILE APETALA (1)
- SULT1A1 (1)
- SULT1B1 (1)
- SUMO (1)
- SVP (1)
- Saccharidbindung (1)
- Saccharose (1)
- Saccharose Synthase (1)
- Salmonellen (1)
- Salztransport (1)
- Samen (1)
- Samenausbreitung (1)
- Sandwich-Assay auf Basis von Aptameren (1)
- Sarkomer (1)
- Saure Seen (1)
- Savanna (1)
- Savanna ecology (1)
- Savanna resilience (1)
- Savannen Resilienz (1)
- Schabe (1)
- Schmalwand <Arabidopsis> (1)
- Schnelltest (1)
- Schutz von Raubtieren (1)
- Schwarzerde (1)
- Schädlinge (1)
- Screening (1)
- Seasonality (1)
- Secondary Metabolites (1)
- Sedimentation (1)
- Seed Coat Development (1)
- Seed development (1)
- Seen (1)
- Seesediment (1)
- Seitenkettenstapel (1)
- Selbstungssyndrom (1)
- Selection of antibody producing cells (1)
- Selection-Linked Integration (1)
- Selektion Antikörper-produzierender Zellen (1)
- Selen (1)
- Senecio vulgaris (1)
- Seneszenz (1)
- Sengis (1)
- Sensor (1)
- Sequenzierungstechnologien der nächsten Generation (1)
- Serin-Biosensor (1)
- Serin-Hydroxymethyltransferase (1)
- Serin-Zyklus (1)
- Serotoninrezeptor (1)
- Shine-Dalgarno sequences (1)
- Shine-Dalgarno-Sequenzen (1)
- Shotgun Sequenzierung (1)
- Shrub encroachment (1)
- Siberian permafrost (1)
- Signalkakaden (1)
- Signalkaskaden (1)
- Signalstoffe (1)
- Signaltransduktionsprozesse (1)
- Signalübertragung (1)
- Signifikanz (1)
- Silene vulgaris (1)
- Simulation (1)
- Simulationsexperimente (1)
- Simulationsframework (1)
- Simulationsmodell (1)
- Single cell level (1)
- Single-cell motility (1)
- Skalierung (1)
- Skeletal robustness (1)
- Skelettrobustizität (1)
- Skleroproteine (1)
- SnRK1 (1)
- Social-ecological systems (1)
- Soil (1)
- Sol-Gel (1)
- Solanum nigrum (1)
- Solidago canadensis (1)
- Solidago gigantea (1)
- Sommerekzem (1)
- Sonchus oleraceus (1)
- Songdialects (1)
- Source und Sink (1)
- South Africa (1)
- Southeast Asia (1)
- Sozialökologische Systeme (1)
- Species number (1)
- Speichelsekretion (1)
- Speicherproteine (1)
- Sphagnum (1)
- Split Ubiquitin (1)
- Stammschleife (1)
- Stammzelldifferenzierung (1)
- Starch metabolism (1)
- Starch synthesis (1)
- Statistical Physics (1)
- Statistische Physik (1)
- Staubblätter (1)
- Stauhaltungen (1)
- Steifheit (1)
- Stethophyma grossum (1)
- Stimuli (1)
- Stimulierung von Zellen (1)
- Stoffkreislauf (1)
- Stoffwechselmodellierung (1)
- Stoffwechselnetze (1)
- Stoffwechselprodukt (1)
- Stoffwechselregulation (1)
- Stomatäre Immunität (1)
- Strahlenbiologie (1)
- Strophentypen (1)
- Struktur (1)
- Strukturelle Thermodynamik (1)
- Strukturproteomics (1)
- Studierendenvorstellungen (1)
- Stärke Synthese (1)
- Stärkeabbau (1)
- Stärkestoffwechsel (1)
- Störungen (1)
- Störungsökologie (1)
- Submarine permafrost (1)
- Submariner Permafrost (1)
- Subsea permafrost (1)
- Substate Channeling Immunoassay (1)
- Substrate channeling immunoassay (1)
- Sukzession (1)
- Sulfit-Oxidase (1)
- Sulfitoxidase (1)
- Sulfotransferasen (1)
- Sulfotransferasen SULT1A1 und SULT1A2 (1)
- Sulfurtransferase (1)
- Sumpfschrecke (1)
- Superoxid (1)
- Superoxiddismutasen (1)
- Superoxide Dismutase (1)
- Support-Vektor-Maschine (1)
- Supramolecular Interaction (1)
- Supramolekularen Wechselwirkung (1)
- Surface Plasmon Resonance (SPR) (1)
- Sustainability (1)
- Symbiose (1)
- Synchronisation (1)
- Synchrotronstrahlung (1)
- Synthetic Biology (1)
- Synthetische Biologie (1)
- Systems biology (1)
- Systemsbiologie (1)
- Säkulare Akzeleration (1)
- Säugetiere (1)
- Südafrika (1)
- Südostasien (1)
- T cell activation (1)
- T-Zell Aktivierung (1)
- T7 (1)
- TACC (1)
- TBK1 (1)
- THC (1)
- TIRF (1)
- TRAP-assay (1)
- TRPV1 (1)
- Tabak (1)
- Tagebaurestseen (1)
- Tagebauseen (1)
- TaiHu (1)
- Tailspike Protein (1)
- Tailspikes (1)
- Talsperre (1)
- Target of Rapamycin kinase (1)
- Tas2r (1)
- Tas2r expression (1)
- Tas2r-Expression (1)
- Tas2rs (1)
- Tbc1d1 (1)
- Telemetrie (1)
- Telomerase (1)
- Theoretische Ökologie (1)
- Theranostic (1)
- Thermistor (1)
- Thermodynamische Stabilität (1)
- Thermometrie (1)
- Thermoregulationsverhalten (1)
- Thioester (1)
- Thioredoxine (1)
- Three Gorges reservoir (1)
- Thylakoid (1)
- Thylakoidmembran (1)
- Tiefe Biosphäre (1)
- Tiefer See (1)
- Tierortung (1)
- Tierpersönlichkeit (1)
- Tierökologie (1)
- Tocopherol (1)
- Tomaten (Solanum lycopersicum) (1)
- Tomato (1)
- Tonoplast (1)
- Torfmoose (1)
- Trade-offs zwischen funktionellen Eigenschaften (1)
- Transaktivierungs-Experimente (1)
- Transcription facotrs (1)
- Transcription factors (1)
- Transcriptome (1)
- Transcriptomics (1)
- Transinformation (1)
- Transkiptionsfaktor (1)
- Transkript (1)
- Transkription <Genetik> (1)
- Transkriptionfaktorgenen (1)
- Transkriptionsnetzwerke (1)
- Transkriptom Sequenzierung (1)
- Transkriptomanalyse (1)
- Translation (1)
- Translation <Genetik> (1)
- Translation feedback regulation (1)
- Translational regulation (1)
- Translationseffizienz (1)
- Translationsfeedbackregulation (1)
- Translationsinitiation (1)
- Translationsregulation (1)
- Transponierbare Elemente (1)
- Transport (1)
- Transporteraktivierung (1)
- Trehalose-6-Phosphat (1)
- Treibhausgase (1)
- Trichome initial cells (1)
- Tripleurospermum inodorum (1)
- Trockentoleranz (1)
- Tumorimmuntherapie (1)
- Tundra-Taiga (1)
- Tupaia belangeri (1)
- TusA (1)
- Typ-III-Effektor (1)
- Tyrosinase (1)
- Tyrosinaseinhibitoren (1)
- UDP-glucose (1)
- Ubiquitin-Proteasom-System (1)
- Ubiquitin-proteasome-system (1)
- Ubiquitinierung (1)
- Umweltfilterung (1)
- Umweltrauschen (1)
- Untereinheitenautausch (1)
- Untereinheitenimpfstoff (1)
- Urbanisation (1)
- Urokinase-Typ Plasminogen Aktivator (uPA) (1)
- Urokinase-type Plasminogen Activator (uPA) (1)
- V. dahliae (1)
- VAP Protein (1)
- VAP protein (1)
- VMP1 (1)
- Variation (1)
- Variation in funktionellen Eigenschaften (1)
- Vegetation (1)
- Vegetation von Tschukotka (1)
- Vegetationsmodellierung (1)
- Vegetationsveränderungen (1)
- Vegetationsveränderungen in der Subarktis (1)
- Vegetationsvielfalt (1)
- Vegetationsökologie (1)
- Verbreitungsdynamik von Arten (1)
- Verbuschung (1)
- Vereinigungs-Mapping (1)
- Verhalten (1)
- Verhaltens-Timing (1)
- Verhaltensökologie (1)
- Vernetzer (1)
- Veronica persica (1)
- Verteidigung (1)
- Verteilungsmuster (1)
- Vesicle (1)
- Videoanalyse (1)
- Vielfalt (1)
- Viral assembly (1)
- Virion (1)
- Virionenbildung (1)
- Virosomen (1)
- Virus-Wirt-Interaktion (1)
- Virusassemblierung, Virion (1)
- Viskoelastizität (1)
- Vitamin C (1)
- Vitamin E (1)
- Vogelzug (1)
- Vorhersagemodelle (1)
- WD40 (1)
- WGCNA (1)
- WRKY40 (1)
- Wachstumsraten (1)
- Wachstumssignale (1)
- Waldausdehnung (1)
- Wasser (1)
- Wasser-in-Wasser (1)
- Wasserabsorption (1)
- Wassererosion (1)
- Wautersia eutropha (1)
- Wechselwirkungen (1)
- Weglänge (1)
- White stork (1)
- Wiederholungsstudie (1)
- Wildschwein (1)
- Winterfischsterben (1)
- Wirkstoff-Freisetzun (1)
- Wirkstoffinteraktionen (1)
- Wirtsspezifität (1)
- Wissensextraktion (1)
- Wurzel (1)
- Wurzelbesiedlung (1)
- Wurzelhaarbildung (1)
- Wühlmaus (1)
- Wüste (1)
- Xanthindehydrogenase (1)
- Xanthomonas (1)
- Xanthomonas campestris pv. vesicatoria (1)
- Xin (1)
- XopS (1)
- Y chromosome (1)
- YnjE (1)
- ZENK (1)
- Zahnwale (1)
- Zeatin (1)
- Zebrafisch (1)
- Zebularin (1)
- Zeitpunkt von Störungen (1)
- Zell-Matrix-Kontakt (1)
- Zell-Matrix-Wechselwirkung (1)
- Zelladhäsion (1)
- Zelladhäsionskontrolle (1)
- Zellbiologie (1)
- Zelle (1)
- Zellform (1)
- Zellfreie Proteinsynthese (1)
- Zellgröße (1)
- Zellmembran (1)
- Zellmotilität (1)
- Zellproliferation (1)
- Zellsignalisierung (1)
- Zellsortierung (1)
- Zellteilung (1)
- Zellteilungsdefekt (1)
- Zelltyp-spezifisch (1)
- Zentrosomen Amplifikation (1)
- Zielkonflikte (1)
- Zink (1)
- Zirkulardichroismus (1)
- Zona pellucida (1)
- Zoo (1)
- Zuckertransporter (1)
- Zugvögel (1)
- Züchtung (1)
- aDNA (1)
- abiotic stress (1)
- abiotischer Stress (1)
- above-ground biomass (1)
- accelerometry (1)
- accessions (1)
- acetylcholinesterase (1)
- acid phosphatase (1)
- acidic lakes (1)
- acinar cell (1)
- actin cytoskeleton machine (1)
- actin/microtubules (1)
- activity (1)
- adaptive Differenzierung (1)
- adaptive Laborentwicklung (1)
- adaptive differentiation (1)
- adaptive laboratory evolution (1)
- adaptive radiation (1)
- adhesion proteins (1)
- age-dependent (1)
- agentenbasiertes Modell (1)
- aggregation (1)
- aggressiveness (1)
- agricultural landscapes (1)
- agroecology (1)
- aldehyde (1)
- aldehyde oxidase (1)
- aldehyde oxidase1 (1)
- alignment (1)
- allochthoner Eintrag (1)
- allochthonous matter (1)
- allometry (1)
- alpha-helix (1)
- alte DNA (1)
- alte sedimentäre DNA (1)
- altered shoot branching (1)
- amino acids (1)
- ammonium (1)
- ammoniumtransporter (1)
- amperometry (1)
- amyloid beta (1)
- analytical approaches (1)
- analytische Lösungsansätze (1)
- ancient sedimentary DNA (1)
- angeborene Immunantwort (1)
- angiogenesis (1)
- animal (1)
- anoxia (1)
- antelope (1)
- anthers (1)
- anthropogene Einwirkung (1)
- anthropogene Umweltveränderungen (1)
- anthropogenic impact (1)
- anthropometry (1)
- anti bacterial (1)
- anti-diuron-antibodies (1)
- antibiotic combinations (1)
- antibiotic resistance (1)
- antibody characterization (1)
- antibody synthesis (1)
- antibody validation (1)
- antimicrobial peptide (1)
- antiviral agent (1)
- aphids (1)
- apoptosis (1)
- apparent hysteresis (1)
- apparente Hysterese (1)
- aptamer-based sandwich assay (1)
- apyrase (1)
- aquatic ecosystem (1)
- aquatische Ökosysteme (1)
- arabidopsis (1)
- arbuscular mycorrhiza (1)
- arbuskuläre Mykorrhiza-Symbiose (1)
- arbuskuläre Mykorrhizasymbiose (1)
- arginine biosynthesis (1)
- arid (1)
- array hybridisation (1)
- artificial transcription factor (1)
- artificial virus (1)
- artifizielle Transkriptionsfaktoren (1)
- arylcarbamates (1)
- arylureas (1)
- ascorbate oxidase (1)
- assembly factor (1)
- assessment of the diffusion (1)
- association (1)
- association mapping (1)
- asymmetric competition (1)
- asymmetrische Konkurrenz (1)
- atomic force microscope (1)
- atrophin-1 (1)
- ausgewogener Komplex (1)
- autonom replizierende Sequenz (1)
- autotrophy (1)
- auxotrophy (1)
- backcross inbred line (BIL) (1)
- bacterial O-antigen (1)
- bacterial infections (1)
- bacterial population growth (1)
- bacterial sensor (1)
- bacteriophage (1)
- bacteriophages (1)
- bakterielle Infektionen (1)
- bakterielles O-Antigen (1)
- balanced complex (1)
- behavioural ecology (1)
- behavioural timing (1)
- belowground herbivory (1)
- benthic food web (1)
- benthic primary producers (1)
- benthische Nahrungskette (1)
- benthische Primärproduzenten (1)
- benzaldehyde (1)
- beta diversity (1)
- beta-Amylase (1)
- beta-Galactosidase (1)
- beta-Solenoidproteine (1)
- beta-amylase (1)
- beta-cell (1)
- beta-solenoid proteins (1)
- bifunctional enzyme (1)
- bifunctional sensor (1)
- bifunktionaler Sensor (1)
- bio-economy (1)
- bioactivation (1)
- biocatalysis (1)
- biocatalytic recycling (1)
- bioelectrocatalytic recycling (1)
- biofilms (1)
- biofouling (1)
- biogas (1)
- biogenesis (1)
- biogenic amine (1)
- biology (1)
- biomass (1)
- biomaterials (1)
- biomechanics (1)
- biomembrane (1)
- biomolecule (1)
- biomolecule interactions (1)
- bioreactor (1)
- biosignatures (1)
- biosynthesis (1)
- biotechnology (1)
- biotopes (1)
- bird migration (1)
- bistability (1)
- bisulfite sequencing (1)
- bitter taste perception (1)
- black earth (1)
- blowfly (1)
- blue light (1)
- bluebuck (1)
- brain (1)
- branched chain amino acids (1)
- breeding (1)
- breeding ability (1)
- brown mosses (1)
- brownification (1)
- bryophytes (1)
- budding yeast (1)
- c-FLIP (1)
- cAMP (1)
- cDNA array (1)
- calcineurin (1)
- calcineurin inhibitors (1)
- calcite (1)
- calcium (1)
- calcium imaging (1)
- calmodulin (1)
- calorimetry (1)
- camera-trap (1)
- canalization (1)
- cancer (1)
- cancer biomarker (1)
- cancer detection (1)
- cancer therapy (1)
- canonical correlation analysis (1)
- capillary electrophoresis (1)
- captivity (1)
- carbohydrate binding site (1)
- carbohydrate interaction (1)
- carbohydrate recognition (1)
- carbohydrate-protein interaction (1)
- carbohydrates (1)
- carbon (1)
- carbon fixation (1)
- carbon flow (1)
- carbon isotopes (1)
- carbon metabolism (1)
- carbon storage (1)
- carboxynitrofluorenone (1)
- cardiac valves (1)
- carry-over effects (1)
- cascading effects (1)
- cat (1)
- catalysis (1)
- catalytic antibodies (1)
- cationic liposome (1)
- cbFBA (1)
- cell (1)
- cell adhesion (1)
- cell adhesion control (1)
- cell cycle (1)
- cell membrane (1)
- cell morphogenesis (1)
- cell motility (1)
- cell proliferation (1)
- cell size (1)
- cell sorting (1)
- cell type-specific (1)
- cell-ECM interactions (1)
- cells epidermis (1)
- cellular bioenergetics (1)
- cellular forces (1)
- cellular signalling (1)
- cellulose biosynthesis inhibitor (1)
- cellulose microfibrils (1)
- cellulose synthesis (1)
- centrosome amplification (1)
- cesa complex (1)
- chemical clock (1)
- chemically induced dislocation (1)
- chemisch-induzierte Dislokation (1)
- chemostat experiments (1)
- chicken repeat 1 (1)
- chlamydomonas reinhardtii (1)
- chloro-ribosome (1)
- chlorophyll (1)
- chromatin immunoprecipitation (1)
- chromosomale Instabilität (1)
- chronic pain (1)
- chronischer Schmerz (1)
- ciliates (1)
- circular dichroism (1)
- cis-trans isomerisation of prolyl-peptide bonds (1)
- classical compartment model (1)
- classical swine fever (1)
- clathrin-coated vesicles (1)
- click chemistry (1)
- close packing (1)
- co-delivery of multiple genes (1)
- co-expression (1)
- co-expression network analysis (1)
- co-response (1)
- co-transfection (1)
- coarse grained Molekulardynamiken (1)
- coarse grained molecular dynamics (1)
- coarse-graining (1)
- coat colour (1)
- cocaine (1)
- coculture (1)
- codon usage (1)
- coexistence mechanisms (1)
- coil-helix (1)
- coiled coils (1)
- cold stress (1)
- coloniality (1)
- colonization credit (1)
- columella (1)
- combinatorial optimization (1)
- combined heat and drought stress (1)
- common-garden experiment (1)
- community (1)
- comparative (1)
- comparative genomics (1)
- competition (1)
- complex model (1)
- compliant mechanism (1)
- compost (1)
- compound eye (1)
- computational biology (1)
- computergestützte Biologie (1)
- confocal microscopy (1)
- connectivity (1)
- conservation breeding (1)
- conservation genetics (1)
- conservation targets (1)
- content knowledge (1)
- contraception (1)
- conventional agriculture (1)
- copolymers (1)
- correlation (1)
- correlation networks (1)
- corrosion (1)
- costamere (1)
- crop (1)
- crops (1)
- cross-striated muscle cells (1)
- crosslinker (1)
- cucurbits (1)
- cupriavidus necator (1)
- cyanobacteria biomarker (1)
- cyclic AMP (1)
- cyclosporin A (1)
- cytochrome c (1)
- cytokinesis (1)
- cytosine methylation (1)
- cytosolic tRNA thiolation (1)
- data analysis and statistics (1)
- data integration (1)
- de novo assembly (1)
- de novo ncRNA Vorhersage (1)
- de novo ncRNA prediction (1)
- deacclimation (1)
- deep lake (1)
- defense (1)
- defense priming (1)
- degradome (1)
- dendritic cell (1)
- dendritische Zelle (1)
- density-dependent (1)
- desert (1)
- detection system (1)
- development (1)
- diacylglycerol (1)
- diagnostic (1)
- diallel (1)
- dichteste Packung (1)
- diet intervention (1)
- diffusion (1)
- disease (1)
- disease persistence (1)
- dispersal behavior (1)
- dissociation (1)
- distance measure (1)
- distribution pattern (1)
- disturbance ecology (1)
- disturbance timing (1)
- diuron (1)
- divalent cations (1)
- division of labor (1)
- doctoral thesis (1)
- domestication (1)
- dopingtest (1)
- drug drug interactions (1)
- drug metabolism (1)
- dynamics (1)
- early warning signals (1)
- earthquake (1)
- eco-hydrological modelling (1)
- ecological interactions (1)
- ecological speciation (1)
- ecological stability (1)
- ecosystem functioning (1)
- ecosystem reconstruction (1)
- ectoparasites (1)
- editing (1)
- effect (1)
- effective daylength (1)
- elastic modulus (1)
- electrochemistry (1)
- electrokinetics (1)
- electron microscopy (1)
- elektrokinetische Effekte (1)
- emulsion (1)
- endophytes (1)
- endosymbiosis (1)
- energetics (1)
- energy budget (1)
- energy metabolism (1)
- energy starvation (1)
- enrichments methods (1)
- environment filtering (1)
- environmental metabolomics (1)
- enzymatische Reaktionsspezifität (1)
- enzyme isoforms (1)
- enzyme kinetic (1)
- enzyme kinetics (1)
- enzyme models (1)
- ephrin (1)
- epigenome editing (1)
- epiphytes (1)
- epithelia (1)
- epithelial salt transport (1)
- epithelial transport (1)
- epithelialer Transport (1)
- epitop prediction (1)
- equus caballus (1)
- erhöhte Nachttemperaturen (1)
- erworbene Immunantwort (1)
- erythropoiesis (1)
- erzeugte Kraft (1)
- essentiality (1)
- establishment (1)
- eukaryotes (1)
- eutrophication (1)
- evolutionary history (1)
- exopolysaccharide (1)
- expression Quantitative Trait Loci (1)
- extinction (1)
- extinction debt (1)
- extinction risk (1)
- extracellular matrix (ECM) (1)
- extravasation-rate limited tissue model (1)
- extrazelluläre Matrix (1)
- fallow land (1)
- feature engineering (1)
- felid conservation (1)
- ferrocene (1)
- fertiliser (1)
- fff (1)
- fiber mesh scaffolds (1)
- fibre optic (1)
- fibroblasts (1)
- filaments (1)
- fire (1)
- fish (1)
- fl (1)
- flavonoid biosynthesis (1)
- floral scent (1)
- flow cytometry (1)
- flow-through biochip scanner (1)
- flower development (1)
- flower ecology (1)
- flower-insect-interaction (1)
- fluorescence correlation spectroscopy (1)
- fluorescence fluctuation spectroscopy (1)
- fluorescent labeling (1)
- fluorescent proteins (1)
- fluoreszierende Proteine (1)
- focal adhesion (1)
- folding (1)
- food allergy (1)
- food analysis (1)
- food web (1)
- food web models (1)
- food webs (1)
- foraging behaviour (1)
- formaldehyde assimilation (1)
- formate (1)
- formate assimilation (1)
- formate dehydrogenases (1)
- fragmentation (1)
- fragments (1)
- freshwater (1)
- freshwater ecology (1)
- freshwater ecosystems (1)
- fruit (1)
- full annual cycle (1)
- functional ecology (1)
- functionalization (1)
- fungi (1)
- funktionale Merkmale (1)
- funktionelle Diversität (1)
- funktionelle Eigenschaften (1)
- funktionelle Ökologie (1)
- fusion (1)
- gastric inhibitory polypeptide receptor (1)
- gelatin (1)
- gelöster organischer Kohlenstoff (1)
- gene cluster activation (1)
- gene expression control (1)
- gene family (1)
- gene regulation (1)
- gene therapy (1)
- generated force (1)
- genetic circuits (1)
- genetic diversity (1)
- genetic fingerprinting (1)
- genetic mosaicism (1)
- genetische Manipulation (1)
- genetische Netzwerke (1)
- genetische Vielfalt (1)
- genetisches Fingerprinting (1)
- genetisches Mosaik (1)
- genome (1)
- genome scan (1)
- genome-wide association studies (GWAS) (1)
- genotype-by-Environmental interaction (GxE) (1)
- genotyping (1)
- geographische Großstudie (1)
- geometric morphometric (1)
- geothermal aquifer (1)
- giant unilamellar vesicles (1)
- giant vesicles (1)
- giving-up density (1)
- glacial refugia (1)
- glass fiber (1)
- glaziale Refugien (1)
- globaler Wandel (1)
- glucolipotoxicity (1)
- glucose dehydrogenase (1)
- glutathione peroxidase-2 GPx2 (1)
- glycine cleavage system (1)
- glycine decarboxylase complex (=GCV) (1)
- glycine synthase complex (reversal of GCV) (1)
- glycogen (1)
- glycosylation (1)
- good-genes-model (1)
- gram-negative (1)
- gramnegativ (1)
- granule formation (1)
- graph theory (1)
- grating coupler (1)
- green house gases (1)
- grobkörnig (1)
- groundwater (1)
- growth (1)
- growth defect (1)
- growthrates (1)
- hADSC (1)
- hCG (1)
- habitat use (1)
- haematopoiesis (1)
- hairy root Transformation (1)
- hand force (1)
- hapten (1)
- haptens (1)
- harvesting (1)
- heart development (1)
- heat stress (1)
- heat stress memory (1)
- hematopoetic stem cells (1)
- hemolysis (1)
- herbicide (1)
- herbicides (1)
- heterocyclic aromatic amine (1)
- heterosis (1)
- heterotrophic bacteria (1)
- heterozyklisches aromatisches Amin (1)
- high light (1)
- high night temperature (1)
- high resolution (1)
- high resolution mass spectrometry (1)
- high throughput sequencing (1)
- histidine-metal coordination (1)
- histone methylation (1)
- hochauflösende Massenspektrometrie (1)
- hohe Auflösung (1)
- hoher Durchsatz Sequenzierung (1)
- holocene (1)
- home range (1)
- horizontal gene transfer (1)
- horizontaler Gentransfer (1)
- horse (1)
- host-specificity (1)
- human (1)
- human aldehyde oxidase (1)
- human metabolic syndrome (1)
- human-induced rapid environmental change (1)
- hybrid breakdown (1)
- hybrid incompatibility (1)
- hybrid variegation (1)
- hybride Inkompatibilität (1)
- hybridization (1)
- hybridization capture (1)
- hybridoma (1)
- hybridoma cells (1)
- hydrogel (1)
- hydrophilicity (1)
- hyperaccumulation (1)
- iatom diversity (1)
- identification (1)
- image analysis (1)
- immune system (1)
- immunoassay; GDH-biosensor; phenolic compounds; on-site-analysis; FIA;ß-galactosidase; wastewater analysis (1)
- immunofluorescence (1)
- immunology (1)
- immunoscreening (1)
- importin (1)
- in vitro immunization (1)
- in-vitro diagnostic (1)
- individual based modeling (1)
- individual-based modelling (1)
- individuelle Modellierung (1)
- individuen-basierte Modellierung (1)
- inducible expression (1)
- inducible gene expression (1)
- induzierbare Genexpression (1)
- inflammation (1)
- influenza A virus (1)
- influenza A viruses (1)
- ingestion (1)
- inheritance (1)
- innate immune response (1)
- insecticides (1)
- insects (1)
- integrative omics analysis (1)
- inter-individual differences (1)
- interaction analysis (1)
- interaction network (1)
- interactions (1)
- interactomics (1)
- intercalated disc (1)
- internalin B (1)
- interspecies interchange (1)
- interspecific interactions (1)
- interspezifische Wechselwirkungen (1)
- intraspecific trait variation (1)
- intraspecific variation (1)
- intraspezifische Merkmalsvariation (1)
- invasion (1)
- invasiv (1)
- invasive (1)
- invertase (1)
- ion mobility spectrometry (IMS) (1)
- ionale Zusammensetzung (1)
- ionic composition (1)
- iron (1)
- iron sulfur clusters (1)
- irreversibel (1)
- irreversible (1)
- isoforms (1)
- isothermal amplification (1)
- isothermale Amplifikation (1)
- jaguar (1)
- joint flexibility (1)
- katalytische Antikörper (1)
- kationische Liposomen (1)
- keratinocytes (1)
- kidney (1)
- kinesin (1)
- kinetic analysis (1)
- kinetic modeling (1)
- kinetische Analyse (1)
- kinetische Modellierung (1)
- klassische Schweinepest (1)
- kombinatorische Optimierung (1)
- kombinierter Hitze- und Trockenstress (1)
- kontrollierte Freisetzung von Biomolekülen (1)
- konventionelle Landwirtschaft (1)
- körperliche Bewegung (1)
- künstlicher Virus (1)
- lab on a chip (1)
- lab-on-a-chip (1)
- lab-on-chip (1)
- lake food web (1)
- lake sediment (1)
- lakes (1)
- land reform (1)
- land use (1)
- land use history (1)
- land-cover classification (1)
- landscape analysis (1)
- landscape heterogeneity (1)
- larch (1)
- large marsh grasshopper (1)
- large scale national conservation plan (1)
- large scale vegetation diversity (1)
- large-scale study (1)
- laser capture microdissection (1)
- latitudinal clines (1)
- leaf width (1)
- learning networks plant (1)
- lebende Materialien (1)
- leghemoglobin (1)
- legionella pneumophila (1)
- legume (1)
- legume lectin (1)
- leucine-rich repeat (1)
- leucine-rich repeat protein (1)
- leucinreiches repeat-Protein (1)
- licht-schaltbare Proteine (1)
- life history (1)
- life-history theory (1)
- light (1)
- light pollution (1)
- light-triggered (1)
- linker (1)
- lipid monolayer (1)
- lipid synthesis (1)
- lipids (1)
- lipophagy (1)
- littoral eutrophication (1)
- living materials (1)
- locomotion (1)
- long-term change (1)
- long-term desiccation (1)
- loss-of-function mutation (1)
- loss-of-function-Mutation (1)
- low NPQ (1)
- lower Havel river wetland (1)
- lysosome (1)
- mAb Disposition (1)
- mAb disposition (1)
- mRNA (1)
- mRNA Degradierung (1)
- mRNA chemistry (1)
- mRNA degradation (1)
- mRNA-Chemie (1)
- machine learning (1)
- machine-learning (1)
- machinelles Lernen (1)
- macrophage activation (1)
- macrophytes (1)
- magnetite Ketter (1)
- magnetotactic bacteria (1)
- magnetotaktische Bakterien (1)
- major hhistocompatibility complex (1)
- maltodextrin (1)
- maltose (1)
- mammalian ALOX15 orthologs (1)
- mammals (1)
- martini (1)
- mass spectrometry (1)
- mathematical simulation models (1)
- mathematische Modelierung (1)
- mathematische Simulationsmodelle (1)
- mathematisches Modellierung (1)
- matrix (1)
- mechanics (1)
- mechanische Mikrodis (1)
- mechanische Stabilität (1)
- mechanistic model (1)
- mechanistisches Modell (1)
- mechanobiology (1)
- mechanosensation (1)
- membrane (1)
- membrane binding (1)
- membrane fluidity (1)
- membrane protein (1)
- merkmalsbasierte Ansätze (1)
- mesenchymal stromal cells (1)
- mesenchymale stromale Zellen (1)
- mesophyll (1)
- metabarcoding (1)
- metabolic (1)
- metabolic Quantitative Trait Loci (1)
- metabolic costs (1)
- metabolic genomics (1)
- metabolic modelling (1)
- metabolic network (1)
- metabolic plasticity (1)
- metabolic regulation (1)
- metabolisch (1)
- metabolische Kosten (1)
- metabolische Modellierung (1)
- metabolischer Phänotyp (1)
- metabolisches Engineering (1)
- metabolisches Modifizieren (1)
- metabolisches Netzwerk (1)
- metabolisches Syndrom (1)
- metabolite breeding (1)
- metabolome (1)
- metabolomic analysis (1)
- metal cation (1)
- methanogene Archaea (1)
- methanogene Archaeen (1)
- methanogens (1)
- methanol assimilation (1)
- methanotrophic bacteria (1)
- methanotrophs (1)
- methanoxidierende Bakterien (1)
- methanproduzierende Archaeen (1)
- methylotrophy (1)
- metric index (1)
- miRNA Regulation (1)
- miRNA regulation (1)
- miRNAs (1)
- micorbicide (1)
- microRNA399 (1)
- microalgae (1)
- microarrays (1)
- microbial activity (1)
- microbial carbon turnover (1)
- microbial community (1)
- microbial decomposition (1)
- microbial diversity (1)
- microbial ecology (1)
- microbial interactions (1)
- microbial soil communities (1)
- microcystis (1)
- microgel (1)
- microheating (1)
- microorganisms (1)
- microsatellites (1)
- microstructures (1)
- microviridin (1)
- microviscosity (1)
- migratory birds (1)
- mikroRNA399 (1)
- mikrobielle Aktivität (1)
- mikrobielle Bodengemeinschaften (1)
- mikrobielle Gemeinschaft (1)
- mikrobielle Interaktionen (1)
- mikrobielle Moor-Kerngemeinschaft (1)
- mikrobielle Vielfalt (1)
- mikrobielle Ökologie (1)
- mikrobieller Abbau (1)
- mikrobieller Kohlenstoffkreislauf (1)
- minimal invasive Probennahme (1)
- minimal invasive sampling (1)
- mining lakes (1)
- misfolding (1)
- mitochondrial transformation (1)
- mitosis (1)
- molecular dating (1)
- molecular dynamics (1)
- molecular dynamics simulation (1)
- molecular farming (1)
- molecular force sensors (1)
- molecular modeling (1)
- molecularly imprinted polymers (1)
- molekular geprägte Polymere (1)
- molekulare Datierung (1)
- molekulare Kraftsensoren (1)
- molybdenum cofactor (1)
- molybdoflavoenzymes (1)
- monitoring (1)
- morphogenesis (1)
- morphological changes (1)
- morphologischen Veränderungen (1)
- morphology (1)
- moss-associated archaea (1)
- moss-associated bacteria (1)
- moss-associated methanogenesis (1)
- moss-associated methanotrophy (1)
- moss-microbe-interactions (1)
- movemen ecology (1)
- mowing (1)
- mulifractional diffusion (1)
- multi-facettierter Diversität (1)
- multi-fraktionelle Diffusion (1)
- multifaceted diversity (1)
- multilayer films (1)
- multiparameter (1)
- multiple sclerosis (1)
- multiplex assay (1)
- multivalency (1)
- multivariate statistische Technik (1)
- murine Tas2rs (1)
- muscle (1)
- musculoskeletal system (1)
- museomics (1)
- mutagenicity (1)
- mutual information (1)
- myotendinous junction (1)
- nacheiszeitliche Wiederbesiedlung (1)
- nanoelectrodes (1)
- nanoparticles (1)
- nanoparticles assembly (1)
- nanostructured materials (1)
- nanostrukturierte Materialien (1)
- national biodiversity hotspots (1)
- nationalen Naturschutzplanung (1)
- nationaler Biodiversitäts-Hotspots (1)
- natural enemies (1)
- natural genetic variation (1)
- natural organic matter (1)
- naturnahe Habitate (1)
- natürliche genetische Variation (1)
- necrosis (1)
- nectar (1)
- net production (1)
- neurite outgrowth (1)
- neurodegeneration (1)
- neurodegenerative (1)
- neurodegenerative Erkrankung (1)
- neuroinflammation (1)
- neuronal networks (1)
- neuronale Netzwerke (1)
- next generation sequencing (NGS) (1)
- niche partitioning (1)
- nicht additiv (1)
- nicht-Mendelsche Vererbung (1)
- nicht-einheimisch (1)
- nicht-kanonische Aminosäuren (1)
- nicht-stöchiometrische Modifikationen (1)
- nichtinvasive Diagnostik (1)
- nitrate (1)
- nitrogen (1)
- nitrogen fixation (1)
- nodulin (1)
- non-Mendelian inheritance (1)
- non-canonical amino acids (1)
- non-equilibrium coexistence (1)
- non-equilibrium dynamics (1)
- non-invasive Diagnostics (1)
- non-native (1)
- non-stoichiometric modifications (1)
- non-target arthropods (1)
- non-target organisms (1)
- nonadditive (1)
- nonlinear (1)
- northern peatlands (1)
- nuclear lamina (1)
- nuclear localization signal (1)
- nucleosidase (1)
- nucleus (1)
- nukleäre Lamina (1)
- null model (1)
- nördliche Moore (1)
- ob/ob (1)
- oberirdische Biomasse (1)
- occupancy (1)
- ocean acidification (1)
- octopamine (1)
- oil palm (1)
- oligomer (1)
- on-chip enzymatic assay (1)
- optimal annual routine model (1)
- optische Biosensoren (1)
- optogenetics (1)
- ordering of particles on the surface (1)
- organelles (1)
- organic carbon (1)
- organic matter (1)
- organic matter quality (1)
- organischer Dünger (1)
- organischer Kohlenstoff (1)
- organophosphate (1)
- osteogenesis (1)
- outcrossing rate (1)
- overacidification (1)
- overgrazing (1)
- oxidase (1)
- oxidative Proteinmodifikationen (1)
- oxidative protein modifications (1)
- oxygen transport (1)
- p-proteins (1)
- p-type ATPase (1)
- pCI (1)
- pH (1)
- pH-Regulation (1)
- pH-regulation (1)
- pPhytoplankton photoacclimation (1)
- pace-of-life syndrome (1)
- pair bonding (1)
- paleovegetation (1)
- palmitate (1)
- paper-based (1)
- paperbased (1)
- papier-basiert (1)
- papierbasiert (1)
- parallele beta-Helix (1)
- parallele rechtsgängige beta-Helix (1)
- parameter estimation (1)
- paramutation (1)
- parasitism (1)
- particulate organic matter (1)
- pathogen (1)
- pathogen bacteria (1)
- pathogen response (1)
- pathogene Bakterien (1)
- pathogens (1)
- pathway mapping (1)
- pathway search (1)
- pattern-oriented modelling (1)
- pavement cell (1)
- pavement cells image analysis (1)
- peatland core microbiome (1)
- peatland development (1)
- pectin (1)
- pectinase (1)
- pelagische Nahrungskette (1)
- peptides (1)
- percentage of body fat (1)
- performance (1)
- periphyton (1)
- permafrost (1)
- permafrost degradation (1)
- perturbation (1)
- pest (1)
- pesticide (1)
- pflanzliche Zellwände (1)
- pflanzliches Immunsystem (1)
- phage HK620 (1)
- phage infection (1)
- phages (1)
- pharmacodynamics (1)
- pharmacokinetics (1)
- pharmakologisches Profil (1)
- phenanthrolindione (1)
- phenol (1)
- phenology (1)
- phenomics (1)
- phenotypic variation (1)
- phloem architecture (1)
- phosphate accumulating organisms (1)
- phosphatidic acid (1)
- phosphoglucan (1)
- phosphoproteomics (1)
- photo-induced (1)
- photoacid (1)
- photoactive proteins (1)
- photoactive yellow protein (PYP) (1)
- photocatalysis (1)
- photoelectrochemical sensor (1)
- photoinduziert (1)
- photoswitches (1)
- photosystem I (1)
- phyllotaxis (1)
- phylogenetic diversity (1)
- phylogeography (1)
- physical activity (1)
- phytol (1)
- phytoplankton and zooplankton (1)
- phytoplankton populations (1)
- phänotypische Variation (1)
- plankton food web (1)
- plant adaptation (1)
- plant cell wall (1)
- plant cell wall biosynthesis (1)
- plant cell walls (1)
- plant communities (1)
- plant functional types (1)
- plant growth (1)
- plant immune system (1)
- plant research (1)
- plant secondary metabolites (1)
- plant-fungal interactions (1)
- plant-microbe interaction (1)
- plant-microbe interactions (1)
- plastid (1)
- pleistocene (1)
- pollen (1)
- pollination (1)
- poly-N-isopropylacrylamide (1)
- polyQ (1)
- polyandry (1)
- polyelectrolyte multilayers (1)
- polyethylene (1)
- polymer membranes (1)
- polymer networks (1)
- polyneuropathy (1)
- polypeptide (1)
- polysaccharides (1)
- ponsin (1)
- population (1)
- population connectivity (1)
- population ecology (1)
- population genetics (1)
- population persistence (1)
- population structure (1)
- porous scaffolds (1)
- poröse Gerüste (1)
- post-translational modifications (1)
- postglacial recolonization (1)
- posttranslationale Modifikationen (1)
- potato tuber (1)
- predator-prey dynamics (1)
- predator-prey relationships (1)
- predictive modelling (1)
- primary human macrophages (1)
- primary producer (1)
- primary production (1)
- primäre humane Makrophagen (1)
- process recovery (1)
- processing (1)
- professional competence (1)
- prostate cancer (1)
- protease inhibitor (1)
- protein aggregation (1)
- protein binding (1)
- protein degradation (1)
- protein domains (1)
- protein folding screen (1)
- protein fusion (1)
- protein kinase (1)
- protein modification (1)
- protein multimerization (1)
- protein phosphatases (1)
- protein phosphorylation (1)
- protein reconstitution (1)
- protein secretion (1)
- protein structure (1)
- protein trafficking (1)
- protein-aptamer interaction (1)
- protein-carbohydrate interactions (1)
- protein-folding (1)
- protein-level regulation (1)
- protein-metal interaction (1)
- protein-protein interactions (1)
- proteins (1)
- proteomics (1)
- punicalagin (1)
- pyrophosphate (1)
- qPCR (1)
- qRT-PCR (1)
- qualitative pathway interpretation (1)
- quantitativen Schutzzielen (1)
- quantum dots (1)
- quiescent center (1)
- radiation biology (1)
- radiocarbon (1)
- randomization (1)
- range shifts (1)
- rare plants (1)
- ratiometric imaging (1)
- reaction rate (1)
- reactive oxygen species (1)
- reactive oxygen species (ROS) (1)
- reaktive Sauerstoffspezies (ROS) (1)
- receptors (1)
- reciprocal transplant experiment (1)
- recombinant production (1)
- recycling system (1)
- red noise (1)
- redox metabolism (1)
- reductive acetyl-CoA pathway (1)
- reduktiver Acetyl-CoA-Weg (1)
- reduktiver Glycinstoffwechselweg (1)
- reduktiver Glycinweg (1)
- regenerative Medizin (1)
- regenerative medicine (1)
- regression methods (1)
- regulatory genes (1)
- regulatory pathway (1)
- repair (1)
- reproduction success (1)
- reproductive success (1)
- reservoirs (1)
- resistance mechanisms (1)
- respiration (1)
- respiratory syncytial virus (1)
- restoration of floodplains (1)
- resurvey (1)
- retrotransposon (1)
- reziprokes Transplantationsexperiment (1)
- rhabdomere twisting (1)
- rheology (1)
- ribosomal dynamics (1)
- ribosome (1)
- ribosome assembly (1)
- ribosome profiling (1)
- ribulose monophosphate pathway (1)
- riesen unilamellare Vesikel (1)
- riesige unilamellare Vesikel (1)
- right-handed parallel beta-helix (1)
- risk assessment (1)
- risk mapping (1)
- root (1)
- root colonization (1)
- root growth (1)
- root hair formation (1)
- root microbiota (1)
- root volatiles (1)
- rotifer (1)
- ruderal (1)
- run length (1)
- räumlich explizites Modell (1)
- räumlich und zeitlich kontrollierte Wirkstoff-Freisetzung (1)
- räumlich-zeitliche Regulierung (1)
- räumliche Autokorrelation (1)
- saccharide binding (1)
- saccharomyces cerevisiae (1)
- saliva (1)
- saliva secretion (1)
- salivary glands (1)
- salt stress (1)
- saure Phosphatase (1)
- savanna (1)
- scale dependence (1)
- scaling (1)
- school-related content knowledge (1)
- schwach elektrische Fische (1)
- schwach elektrischer Fisch (1)
- schwankendes Licht (1)
- screening (1)
- second messenger (1)
- secondary metabolism (1)
- secondary metabolites (1)
- secular acceleration (1)
- sedaDNA (1)
- sedimentary ancient DNA (1)
- sedimentation (1)
- seed dispersal (1)
- seeds (1)
- seismic activity (1)
- seismische Aktivität (1)
- sekundäre Pflanzenstoffe (1)
- selbstheilende Materialien (1)
- selection (1)
- selection-linked integration (1)
- selenium (1)
- self-healing materials (1)
- selfing syndrome (1)
- seltene Pflanzen (1)
- semi-natural habitat (1)
- senescence (1)
- sengis (1)
- sensor (1)
- sequencing (1)
- serine biosensor (1)
- serine cycle (1)
- serine hydroxymethyltransferase (1)
- setting back dykes (1)
- shape-memory polymer (1)
- shape-memory polymers (1)
- short vegetative phase (1)
- shotgun sequencing (1)
- shrubification (1)
- sibirischen Permafrost (1)
- side chain stacking (1)
- signal compounds (1)
- signaling (1)
- signalling (1)
- signalling pathways (1)
- significance (1)
- simulation (1)
- simulation experiments (1)
- simulation framework (1)
- simulation model (1)
- simultane Einbringung multipler Gene (1)
- singing activity (1)
- single cell analysis (1)
- single cell imaging (1)
- single cell sammpling and analysis (SCSA) (1)
- single molecule force spectroscopy (1)
- single nucleotide polymorphisms (1)
- single-cell (1)
- single-cell RNA-sequencing (1)
- single-cell analysis (1)
- small mammals (1)
- soft actuators (1)
- soil organic carbon (1)
- sol-gel (1)
- solanum tuberosum (1)
- solid-state MAS NMR (1)
- somatotype (1)
- song-matching (1)
- song-sharing (1)
- song-types (1)
- songlearning (1)
- source and sink (1)
- space use (1)
- spatial autocorrelation (1)
- spatially and temporally controlled drug release (1)
- spatially explicit model (1)
- spatio-temporal regulation (1)
- specialized metabolites (1)
- species distribution modelling (1)
- species distribution models (1)
- stabile Isotope Tracer (1)
- stable isotope tracer (1)
- stable isotope tracing (1)
- starch degradation (1)
- starch granule morphology (1)
- starch granule surface (1)
- starch metabolism (1)
- starch phosphorylation (1)
- stem cell differentiation (1)
- stem loop (1)
- stewartan (1)
- stiffness (1)
- stimulation of cells (1)
- stimuli (1)
- stochastic dynamic programming (1)
- stochastic modeling (1)
- stochastisch-dynamische Optimierung (1)
- stochastische Modellierung (1)
- stoichiometric modeling (1)
- stomatal immunity (1)
- storage proteins (1)
- stress (1)
- structural genomics (1)
- structural thermodynamics (1)
- structure (1)
- structure-function (1)
- style (1)
- stöchiometrische Modellierung (1)
- subarctic vegetation change (1)
- submarin (1)
- submarine (1)
- subunit exchange (1)
- subunit vaccine (1)
- succession (1)
- sucrose synthase (1)
- sugar transporter (1)
- sulfadiazine (1)
- sulfotranferases (1)
- sulfotransferases SULT1A1 and SULT1A2 (1)
- sulfur (1)
- sulfur transferase (1)
- sulphur (1)
- summer eczema (1)
- superoxide (1)
- support vector machine (1)
- suppressor mutant screen (1)
- surface charge (1)
- surface chemistry (1)
- surface temperature (1)
- survival rate (1)
- sustainable land use (1)
- sustainable management (1)
- symbiose-relevante mikroRNA-Targets (1)
- symbiosis-relevant microRNA targets (1)
- symplastic loading (1)
- synchronization (1)
- synchrotron radiation (1)
- synthetic formatotrphy (1)
- synthetic metabolism (1)
- synthetischer Metabolismus (1)
- systemsbiology (1)
- tRNA Thiomodifikation (1)
- tRNA thiomodifications (1)
- tailspike protein (1)
- target enrichment (1)
- targeted therapy (1)
- taste (1)
- tbr mutant (1)
- telemetry (1)
- temperatur-sensitive (1)
- temperature (1)
- temperature sensitive foldi (1)
- terra preta (1)
- terrestrial (1)
- terrestrisch (1)
- theoretical ecology (1)
- theoretische Ökologie (1)
- thermo-responsive Polymere (1)
- thermo-responsive polymers (1)
- thermometry (1)
- thermoplastic polymers (1)
- thermoplastischen Polymere (1)
- thermoregulatory behaviour (1)
- thermoresponsive (1)
- thermoresponsive Polymere (1)
- thermoresponsive polymers (1)
- thick ascending limb (1)
- thioester (1)
- thioredoxin (1)
- threatened (1)
- three-state model (1)
- thylakoid (1)
- thylakoid membranes (1)
- tiefe Biosphäre (1)
- time-kill curves (1)
- tobramycin (1)
- tocopherol (1)
- tomato (1)
- tomato (Solanum lycopersicum) (1)
- tomato(Solanum lycopersicum) (1)
- toothed whales (1)
- tracking (1)
- tracking impacts (1)
- trade-off (1)
- trade-offs between functional traits (1)
- tradeoff (1)
- trait adaptation (1)
- trait diversity (1)
- trait-based approaches (1)
- trans-Golgi Netzwerk (1)
- trans-Golgi network (1)
- transactivation assay (1)
- transcript (1)
- transcription (1)
- transcription factor genes (1)
- transcriptome (1)
- transcriptome analysis (1)
- transcriptome sequencing (1)
- transepitheliales Potential (1)
- transfer (1)
- transgenes Mausmodell (1)
- transgenic (1)
- transgenic mouse model (1)
- transient receptor potential ion channels (1)
- transient-receptor-potential-Ionenkanäle (1)
- transition metals (1)
- transitorische Stärke (1)
- translation efficiency (1)
- translation initiation (1)
- transport (1)
- transposable elements (1)
- tree infilling (1)
- treeline (1)
- treeline dynamics (1)
- tritrophic system (1)
- tritrophisches System (1)
- trophic apparatus (1)
- trophic transfer efficiency (1)
- trophische Transfereffizienz (1)
- tropische Süßwasser Fische (1)
- tropische Süßwasserfische (1)
- tuber second growth (1)
- tuberization (1)
- tumor immunotherapy (1)
- tundra-taiga (1)
- type-III effector (1)
- tyrosinase (1)
- tyrosinase inhibitors (1)
- ubiquitin (1)
- udp-galacturonic acid (1)
- udp-rhamnose (1)
- ungulates (1)
- untere Havelniederung (1)
- unterirdische Pflanzenfresser (1)
- urban soil erosion (1)
- urbane Bodenerosion (1)
- urbanization (1)
- variation (1)
- vegetation change (1)
- vegetation ecology (1)
- vegetation modeling (1)
- velocity (1)
- vergleichend (1)
- vergleichende Genomik (1)
- verzweigtkettige Aminosäuren (1)
- veränderte Triebverzweigung (1)
- vesicle (1)
- vesicle transport (1)
- video analysis (1)
- viral fitness (1)
- viral infections (1)
- virale Infektionen (1)
- virosome (1)
- virulence-associated genes (1)
- virulenzassoziierte Gene (1)
- virus assembly (1)
- virus-host interaction (1)
- viscoelasticity (1)
- vitamin E (1)
- volatile organic compounds (VOCs) (1)
- volatile organische Substanzen (VOCs) (1)
- vollständiger Jahreszyklus (1)
- water (1)
- water absorbance (1)
- water erosion (1)
- water reservoir (1)
- water-in-water (1)
- wechselseitige Information (1)
- weiche Aktuatoren (1)
- western Eger Rift (1)
- westlichen Eger-Graben (1)
- wheat (1)
- white stork (1)
- whole chromosomal instability (1)
- whole genome (1)
- wild boar (1)
- winter fish kill (1)
- woodland (1)
- woody encroachment (1)
- yield (1)
- zeatin (1)
- zebrafish (1)
- zebularine (1)
- zellfreie Proteinsynthese (1)
- zellulose, Salzstress (1)
- zelluläre Bioenergetik (1)
- zelluläre Kräfte (1)
- zelluläre Signalübertragung (1)
- zinc (1)
- zona pellucida (1)
- zweiwertige Kationen (1)
- zwitterionic phospholipids (1)
- zwitterionische Phospholipide (1)
- zytosolische tRNA-Thiolierung (1)
- ÁtAMT2 (1)
- Ähnlichkeitsmaß (1)
- Öko-Ethologie (1)
- Ökokline (1)
- Ökologische Modelle (1)
- Ökosystem (1)
- Ökosystem-Rekonstruktion (1)
- Ökosystementwicklung (1)
- Ökosystemfunktion (1)
- Ökotoxikologie (1)
- Ökotypen (1)
- Übergangsmetalle (1)
- Übersäuerung (1)
- öffentliche Gesundheit (1)
- ökohydrologische Modellierung (1)
- ökologische Stabilität (1)
Institute
- Institut für Biochemie und Biologie (1051) (remove)
Development of a CRISPR/Cas gene editing technique for the coccolithophore Chrysotila carterae
(2024)
Actin is one of the most highly conserved proteins in eukaryotes and distinct actin-related proteins with filament-forming properties are even found in prokaryotes. Due to these commonalities, actin-modulating proteins of many species share similar structural properties and proposed functions. The polymerization and depolymerization of actin are critical processes for a cell as they can contribute to shape changes to adapt to its environment and to move and distribute nutrients and cellular components within the cell. However, to what extent functions of actin-binding proteins are conserved between distantly related species, has only been addressed in a few cases. In this work, functions of Coronin-A (CorA) and Actin-interacting protein 1 (Aip1), two proteins involved in actin dynamics, were characterized. In addition, the interchangeability and function of Aip1 were investigated in two phylogenetically distant model organisms. The flowering plant Arabidopsis thaliana (encoding two homologs, AIP1-1 and AIP1-2) and in the amoeba Dictyostelium discoideum (encoding one homolog, DdAip1) were chosen because the functions of their actin cytoskeletons may differ in many aspects. Functional analyses between species were conducted for AIP1 homologs as flowering plants do not harbor a CorA gene.
In the first part of the study, the effect of four different mutation methods on the function of Coronin-A protein and the resulting phenotype in D. discoideum was revealed in two genetic knockouts, one RNAi knockdown and a sudden loss-of-function mutant created by chemical-induced dislocation (CID). The advantages and disadvantages of the different mutation methods on the motility, appearance and development of the amoebae were investigated, and the results showed that not all observed properties were affected with the same intensity. Remarkably, a new combination of Selection-Linked Integration and CID could be established.
In the second and third parts of the thesis, the exchange of Aip1 between plant and amoeba was carried out. For A. thaliana, the two homologs (AIP1-1 and AIP1-2) were analyzed for functionality as well as in D. discoideum. In the Aip1-deficient amoeba, rescue with AIP1-1 was more effective than with AIP1-2. The main results in the plant showed that in the aip1-2 mutant background, reintroduced AIP1-2 displayed the most efficient rescue and A. thaliana AIP1-1 rescued better than DdAip1. The choice of the tagging site was important for the function of Aip1 as steric hindrance is a problem. The DdAip1 was less effective when tagged at the C-terminus, while the plant AIP1s showed mixed results depending on the tag position. In conclusion, the foreign proteins partially rescued phenotypes of mutant plants and mutant amoebae, despite the organisms only being very distantly related in evolutionary terms.
Arachidonsäurelipoxygenasen (ALOX-Isoformen) sind Lipid-peroxidierenden Enzyme, die bei der Zelldifferenzierung und bei der Pathogenese verschiedener Erkrankungen bedeutsam sind. Im menschlichen Genom gibt es sechs funktionelle ALOX-Gene, die als Einzelkopiegene vorliegen. Für jedes humane ALOX-Gen gibt es ein orthologes Mausgen. Obwohl sich die sechs humanen ALOX-Isoformen strukturell sehr ähnlich sind, unterscheiden sich ihre funktionellen Eigenschaften deutlich voneinander. In der vorliegenden Arbeit wurden vier unterschiedliche Fragestellungen zum Vorkommen, zur biologischen Rolle und zur Evolutionsabhängigkeit der enzymatischen Eigenschaften von Säugetier-ALOX-Isoformen untersucht:
1) Spitzhörnchen (Tupaiidae) sind evolutionär näher mit dem Menschen verwandt als Nagetiere und wurden deshalb als Alternativmodelle für die Untersuchung menschlicher Erkrankungen vorgeschlagen. In dieser Arbeit wurde erstmals der Arachidonsäurestoffwechsel von Spitzhörnchen untersucht. Dabei wurde festgestellt, dass im Genom von Tupaia belangeri vier unterschiedliche ALOX15-Gene vorkommen und die Enzyme sich hinsichtlich ihrer katalytischen Eigenschaften ähneln. Diese genomische Vielfalt, die weder beim Menschen noch bei Mäusen vorhanden ist, erschwert die funktionellen Untersuchungen zur biologischen Rolle des ALOX15-Weges. Damit scheint Tupaia belangeri kein geeigneteres Tiermodel für die Untersuchung des ALOX15-Weges des Menschen zu sein.
2) Entsprechend der Evolutionshypothese können Säugetier-ALOX15-Orthologe in Arachidonsäure-12-lipoxygenierende- und Arachidonsäure-15-lipoxygenierende Enzyme eingeteilt werden. Dabei exprimieren Säugetierspezies, die einen höheren Evolutionsgrad als Gibbons aufweisen, Arachidonsäure-15-lipoxygenierende ALOX15-Orthologe, während evolutionär weniger weit entwickelte Säugetiere Arachidonsäure-12 lipoxygenierende Enzyme besitzen. In dieser Arbeit wurden elf neue ALOX15-Orthologe als rekombinante Proteine exprimiert und funktionell charakterisiert. Die erhaltenen Ergebnisse fügen sich widerspruchsfrei in die Evolutionshypothese ein und verbreitern deren experimentelle Basis. Die experimentellen Daten bestätigen auch das Triadenkonzept.
3) Da humane und murine ALOX15B-Orthologe unterschiedliche funktionelle Eigenschaften aufweisen, können Ergebnisse aus murinen Krankheitsmodellen zur biologischen Rolle der ALOX15B nicht direkt auf den Menschen übertragen werden. Um die ALOX15B-Orthologen von Maus und Mensch funktionell einander anzugleichen, wurden im Rahmen der vorliegenden Arbeit Knock-in Mäuse durch die In vivo Mutagenese mittels CRISPR/Cas9-Technik hergestellt. Diese exprimieren eine humanisierte Mutante (Doppelmutation von Tyrosin603Asparaginsäure+Histidin604Valin) der murinen Alox15b. Diese Mäuse waren lebens- und fortpflanzungsfähig, zeigten aber geschlechtsspezifische Unterschiede zu ausgekreuzten Wildtyp-Kontrolltieren im Rahmen ihre Individualentwicklung.
4) In vorhergehenden Untersuchungen zur Rolle der ALOX15B in Rahmen der Entzündungsreaktion wurde eine antiinflammatorische Wirkung des Enzyms postuliert. In der vorliegenden Arbeit wurde untersucht, ob eine Humanisierung der murinen Alox15b die Entzündungsreaktion in zwei verschiedenen murinen Entzündungsmodellen beeinflusst. Eine Humanisierung der murinen Alox15b führte zu einer verstärkten Ausbildung von Entzündungssymptomen im induzierten Dextran-Natrium-Sulfat-Kolitismodell. Im Gegensatz dazu bewirkte die Humanisierung der Alox15b eine Abschwächung der Entzündungssymptome im Freund‘schen Adjuvans Pfotenödemmodell. Diese Daten deuten darauf hin, dass sich die Rolle der ALOX15B in verschiedenen Entzündungsmodellen unterscheidet.
Microalgae have been recognized as a promising green production platform for recombinant proteins. The majority of studies on recombinant protein expression have been conducted in the green microalga C. reinhardtii. While promising improvement regarding nuclear transgene expression in this alga has been made, it is still inefficient due to epigenetic silencing, often resulting in low yields that are not competitive with other expressor organisms. Other microalgal species might be better suited for high-level protein expression, but are limited in their availability of molecular tools.
The red microalga Porphyridium purpureum recently emerged as candidate for the production of recombinant proteins. It is promising in that transformation vectors are episomally maintained as autonomously replicating plasmids in the nucleus at a high copy number, thus leading to high expression values in this red alga.
In this work, we expand the genetic tools for P. purpureum and investigate parameters that govern efficient transgene expression. We provide an improved transformation protocol to streamline the generation of transgenic lines in this organism. After being able to efficiently generate transgenic lines, we showed that codon usage is a main determinant of high-level transgene expression, not only at the protein level but also at the level of mRNA accumulation. The optimized expression constructs resulted in YFP accumulation up to an unprecedented 5% of the total soluble protein. Furthermore, we designed new constructs conferring efficient transgene expression into the culture medium, simplifying purification and harvests of recombinant proteins. To further improve transgene expression, we tested endogenous promoters driving the most highly transcribed genes in P. purpureum and found minor increase of YFP accumulation.
We employed the previous findings to express complex viral antigens from the hepatitis B virus and the hepatitis C virus in P. purpureum to demonstrate its feasibility as producer of biopharmaceuticals. The viral glycoproteins were successfully produced to high levels and could reach their native confirmation, indicating a functional glycosylation machinery and an appropriate folding environment in this red alga. We could successfully upscale the biomass production of transgenic lines and with that provide enough material for immunization trials in mice that were performed in collaboration. These trials showed no toxicity of neither the biomass nor the purified antigens, and, additionally, the algal-produced antigens were able to elicit a strong and specific immune response.
The results presented in this work pave the way for P. purpureum as a new promising producer organism for biopharmaceuticals in the microalgal field.
Heat stress (HS) is a major abiotic stress that negatively affects plant growth and productivity. However, plants have developed various adaptive mechanisms to cope with HS, including the acquisition and maintenance of thermotolerance, which allows them to respond more effectively to subsequent stress episodes. HS memory includes type II transcriptional memory which is characterized by enhanced re-induction of a subset of HS memory genes upon recurrent HS. In this study, new regulators of HS memory in A. thaliana were identified through the characterization of rein mutants.
The rein1 mutant carries a premature stop in CYCLIN-DEPENDENT-KINASE 8 (CDK8) which is part of the cyclin kinase module of the Mediator complex. Rein1 seedlings show impaired type II transcriptional memory in multiple heat-responsive genes upon re-exposure to HS. Additionally, the mutants exhibit a significant deficiency in HS memory at the physiological level. Interaction studies conducted in this work indicate that CDK8 associates with the memory HEAT SHOCK FACTORs HSAF2 and HSFA3. The results suggest that CDK8 plays a crucial role in HS memory in plants together with other memory HSFs, which may be potential targets of the CDK8 kinase function. Understanding the role and interaction network of the Mediator complex during HS-induced transcriptional memory will be an exciting aspect of future HS memory research.
The second characterized mutant, rein2, was selected based on its strongly impaired pAPX2::LUC re-induction phenotype. In gene expression analysis, the mutant revealed additional defects in the initial induction of HS memory genes. Along with this observation, basal thermotolerance was impaired similarly as HS memory at the physiological level in rein2. Sequencing of backcrossed bulk segregants with subsequent fine mapping narrowed the location of REIN2 to a 1 Mb region on chromosome 1. This interval contains the At1g65440 gene, which encodes the histone chaperone SPT6L. SPT6L interacts with chromatin remodelers and bridges them to the transcription machinery to regulate nucleosome and Pol II occupancy around the transcriptional start site. The EMS-induced missense mutation in SPT6L may cause altered HS-induced gene expression in rein2, possibly triggered by changes in the chromatin environment resulting from altered histone chaperone function.
Expanding research on screen-derived factors that modify type II transcriptional memory has the potential to enhance our understanding of HS memory in plants. Discovering connections between previously identified memory factors will help to elucidate the underlying network of HS memory. This knowledge can initiate new approaches to improve heat resilience in crops.
This work analyzed functional and regulatory aspects of the so far little characterized EPSIN N-terminal Homology (ENTH) domain-containing protein EPSINOID2 in Arabidopsis thaliana. ENTH domain proteins play accessory roles in the formation of clathrin-coated vesicles (CCVs) (Zouhar and Sauer 2014). Their ENTH domain interacts with membranes and their typically long, unstructured C-terminus contains binding motifs for adaptor protein complexes and clathrin itself. There are seven ENTH domain proteins in Arabidopsis. Four of them possess the canonical long C-terminus and participate in various, presumably CCV-related intracellular transport processes (Song et al. 2006; Lee et al. 2007; Sauer et al. 2013; Collins et al. 2020; Heinze et al. 2020; Mason et al. 2023). The remaining three ENTH domain proteins, however, have severely truncated C-termini and were termed EPSINOIDs (Zouhar and Sauer 2014; Freimuth 2015). Their functions are currently unclear. Preceding studies focusing on EPSINOID2 indicated a role in root hair formation: epsinoid2 T DNA mutants exhibited an increased root hair density and EPSINOID2-GFP was specifically located in non-hair cell files in the Arabidopsis root epidermis (Freimuth 2015, 2019).
In this work, it was clearly shown that loss of EPSINOID2 leads to an increase in root hair density through analyses of three independent mutant alleles, including a newly generated CRISPR/Cas9 full deletion mutant. The ectopic root hairs emerging from non-hair positions in all epsinoid2 mutant alleles are most likely not a consequence of altered cell fate, because extensive genetic analyses placed EPSINOID2 downstream of the established epidermal patterning network. Thus, EPSINOID2 seems to act as a cell autonomous inhibitor of root hair formation. Attempts to confirm this hypothesis by ectopically overexpressing EPSINOID2 led to the discovery of post-transcriptional and -translational regulation through different mechanisms. One involves the little characterized miRNA844-3p. Interference with this pathway resulted in ectopic EPSINOID2 overexpression and decreased root hair density, confirming it as negative factor in root hair formation. A second mechanism likely involves proteasomal degradation. Treatment with proteasomal inhibitor MG132 led to EPSINOID2-GFP accumulation, and a KEN box degron motif was identified in the EPSINOID2 sequence associated with degradation through a ubiquitin/proteasome-dependent pathway. In line with a tight dose regulation, genetic analyses of all three mutant alleles indicate that EPSINOID2 is haploinsufficient. Lastly, it was revealed that, although EPSINOID2 promoter activity was found in all epidermal cells, protein accumulation was observed in N-cells only, hinting at yet another layer of regulation.
The plant cell wall plays several crucial roles during plant development with its integrity acting as key signalling component for growth regulation during biotic and abiotic stresses. Cellulose microfibrils, the principal load-bearing components is the major component of the primary cell wall, whose synthesis is mediated by microtubule-associated CELLULOSE SYNTHASE (CESA) COMPLEXES (CSC). Previous studies have shown that CSC interacting proteins COMPANION OF CELLULOSE SYNTHASE (CC) facilitate sustained cellulose synthesis during salt stress by promoting repolymerization of cortical microtubules. However, our understanding of cellulose synthesis during salt stress remains incomplete.
In this study, a pull-down of CC1 protein led to the identification of a novel interactor, termed LEA-like. Phylogenetic analysis revealed that LEA-like belongs to the LATE EMBRYOGENESIS ABUNDANT (LEA) protein family, specifically to the LEA_2 subgroup, showing a close relationship with the CC proteins. Roots of the double mutants lea-like and its closest homolog emb3135 exhibited hypersensitivity when grown on cellulose synthesis inhibitors. Further analysis of higher-order mutants of lea-like, emb3135, and cesa6 demonstrated a genetic interaction between them indicating a significant role in cellulose synthesis.
Live-cell imaging revealed that both LEA-like and EMB3135 migrated with the CSC at the plasma membrane along microtubule tracks in control and oryzalin-treated conditions which destabilize microtubules, suggesting a tight interaction. Investigation of fluorescently labeled lines of different domains of the LEA-like protein revealed that the N-terminal cytosolic domain of LEA-like colocalizes with microtubules, suggesting a physical association between the two.
Considering the established role of LEA proteins in abiotic stress tolerance, we performed phenotypic analysis of the mutant under various stresses. Growth of double mutants of lea-like and emb3135 on NaCl containing media resulted in swelling of root cell indicating a putative role in salt stress tolerance. Supportive of this the quadruple mutant, lacking LEA-like, EMB3135, CC1, and CC2 proteins, exhibited a severe root growth defect on NaCl media compared to control conditions. Live-cell imaging revealed that under salt stress, the LEA-like protein forms aggregates in the plasma membrane.
In conclusion, this study has unveiled two novel interactors of the CSC that act with the CC proteins that regulate plant growth in response to salt stress providing new insights into the intricate regulation of cellulose synthesis, particularly under such conditions.
The inclusion of exotic germplasm serves as a crucial means to enhance allelic and
consequently phenotypic diversity in inbred crop species. Such species have experienced a reduction in diversity due to artificial selection focused on a limited set of traits. The natural biodiversity within ecosystems presents an opportunity to explore various traits influencing plant survival, reproductive fitness and yield potential. In agricultural research, the study of wild species closely related to cultivated plants serves as a means to comprehend the genetic foundations of past domestication events and the polymorphisms essential for future breeding efforts to develop superior varieties. In order to examine the metabolic composition, pinpoint quantitative trait loci (QTL) and facilitate their resolution an extensive large-scale analysis of metabolic QTL (mQTL) was conducted on tomato backcross inbred lines (BILs) derived from a cross between the wild species S. pennellii (5240) incorporated into the background of S. lycopersicum cv. LEA determinate inbred which can be grown in open fields and cv. TOP indeterminate which can be grown in greenhouse conditions. A large number of mQTL associated with primary secondary and lipid metabolism in fruit were identified across the two BIL populations. Epistasis, the interactions between genes at different loci, has been an interest in molecular and quantitative genetics for many decades. The study of epistasis requires the analysis of very large populations with multiple independent genotypes that carry specific genomic regions. In order to understand the genetic basis of tomato fruit metabolism, I extended the work to investigate epistatic interactions of the genomic regions. In addition, two candidate genes were identified through quantitative trait loci underlying fruit-specific sucrose and jasmonic acid derivatives. Finally, in this study, I assessed the genetic framework of fruit metabolic traits with a high level of detail, utilizing the newly created Solanum pennellii (5240) backcrossed introgression lines (n=3000). This investigation resulted in the discovery of promising candidate loci associated with significant fruit quality traits, including those to the abundance of glutamic acid and aspartic acid crucial elements contributing to the development of acidity and flavors.