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Foreland-basin systems are excellent archives to decipher the feedbacks between surface and tectonic processes in orogens. The sedimentary architecture of a foreland-basin system reflects the balance between tectonic subsidence causing long-term accommodation space and sediment influx corresponding to efficiency of erosion and mass-redistribution processes. In order to explore the effects of climatic and tectonic forcing in such a system, I investigated the Oligo-Miocene foreland-basin sediments of the southern Alborz mountains, an intracontinental orogen in northern Iran, related to the Arabia-Eurasia continental collision. This work includes absolute dating methods such as 40Ar/39Ar and zircon (U-Th)/He thermochronology, magnetostratigraphy, sedimentological analysis, sandstone and conglomerate provenance study, carbon and oxygen isotope analysis, and clay mineralogy study. Results show a systematic correlation between coarsening-upward cycles and sediment accumulation rates in the basin on 105 to 106yr time scales. During thrust loading phases, the coarse-grained fraction supplied by the uplifting range is stored in the proximal part of the basin (sedimentary facies retrogradation), while fine-grained sediments are deposited in distal sectors. Variations in sediment provenance during these phases of enhanced tectonic activity give evidence for erosional unroofing phases and/or drainage-reorganization events. In addition, enhanced tectonic activity promoted the growth of topography and associated orographic barrier effects, as demonstrated by sedimentologic indicators and the analysis of stable C and O isotopes from calcareous paleosols and lacustrine/palustrine samples. Extensive progradation of coarse-grained deposits occurs during phases of decreased subsidence, when the coarse-grained fraction supplied by the uplifting range cannot be completely stored in the proximal part of the basin. In this environment, a reduction in basin subsidence is associated with laterally stacked fluvial channel deposits, and is related to intra-foreland uplift, as documented by growth strata, tectonic tilting, and sediment reworking. Increase in sediment accumulation rate associated with progradation of vertically-stacked coarse-grained fluvial channels also occurs. Paleosol O-isotope data shows that this increase is related to wetter climatic phases, suggesting that surface processes are more efficient and exhumation rates increase, giving rise to a positive feedback. Furthermore, isotopic and sedimentologic data show that starting from 10-9 Ma, climate became less arid with an increase in seasonality of precipitation. Because important changes were also recorded in the Mediterranean Sea and Asia at that time, the evidence for climatic variability observed in the Alborz mountains most likely reflects changes in Northern Hemisphere atmospheric circulation patterns. This study has additional implications for the evolution of the Alborz mountains and the Arabia-Eurasia continental collision zone. At the orogenic scale, the locus of deformation did not move steadily southward, but stepped forward and backward since Oligocene time. In particular, from ~ 17.5 to 6.2 Ma the orogen grew by a combination of frontal accretion and wedge-internal deformation on time scales of ca. 0.7 to 2 m.y. Moreover, the provenance data suggest that prior to 10-9 Ma the shortening direction changed from NW-SE to NNE-SSW, in agreement with structural data. On the scale of the entire collision zone, the evolution of the studied basins and adjacent mountain ranges suggests a new geodynamic model for the evolution of the Arabia-Eurasia continental collision zone. Numerous sedimentary basins in the Alborz mountains and in other locations of the Arabia-Eurasia collision zone record a change from a tensional (transtensional) to a compressional (transpressional) tectonic setting by ~ 36 Ma. I interpret this to reflect the onset of subduction of the stretched Arabian continental lithosphere beneath central Iran, leading to moderate plate coupling and lower- and upper-plate deformation (soft continental collision). The increase in deformation rates in the southern Alborz mountains from ~ 17.5 Ma suggests that significant upper-plate deformation must have started by the early Miocene most likely in response to an increase in degree of plate coupling. I suggest that this was related to the subduction of thicker Arabian continental lithosphere and the consequent onset of hard continental collision. This model reconciles the apparent lag time of 15-20 m.y between the late Eocene to early Oligocene age for the initial Arabia-Eurasia continental collision and the onset of widespread deformation across the collision zone to the north in early to late Miocene time.
Die weltweite Forderung nach einer Zunahme der gesellschaftlichen Verantwortung der Unternehmen ist in den letzten Jahren über alle Anspruchsgruppen (Stakeholder) hinweg stetig größer geworden.1 Die Übernahme eben dieser Verantwortung findet in dem facettenreichen Begriff der Corporate Social Responsibility (CSR) ihren Ausdruck. Diesem Leitbild entsprechend verpflichten sich Unternehmen zum verantwortungsbewussten Verhalten gegenüber Eigentümern, Konsumenten, Lieferanten, Mitarbeitern und der Gesellschaft als Ganzes.2 Eine CSR-Strategie, die ein ausgewogenes Maß der ‘Triple-Bottom-Line’ bestehend aus sozialen, ökologischen und ökonomischen Aspekten berücksichtigt, wird mittlerweile als Notwendigkeit dafür angesehen, dass ein Unternehmen auch in Zukunft seine ‘license to operate’, d.h. seine gesellschaftliche Unterstützung für die Geschäftstätigkeit behält bzw. sichert.
Cause related Marketing
(2009)
Das Buch beschäftigt sich mit der Frage, wie sich mit den Prozessen gesellschaftlicher Transformation nicht nur das individuelle wie kollektive Handeln, sondern auch das darauf bezogene Lernen verändert. Im Zentrum steht die reflexive Analyse, Konstituierung und Entwicklung eines Lernens im Kontext gesellschaftlich-historischen Wandels. Dies wird aus erwachsenenpädagogischer Perspektive als komplexe Entwicklungs-, Organisations- und Gestaltungsaufgabe entfaltet. Dabei werden die wissenschaftskonzeptionellen Arbeiten des Psychologen Klaus Holzkamp herangezogen, um Grundlagenprobleme hinsichtlich der Konstituierung eines gesellschaftlich vermittelten Lernbegriffes zu analysieren und um diese im Anschluss an die Diskurse des "Cultural Turn" in Richtung einer kulturtheoretischen Fundierung zu überwinden. Holzkamps subjektwissenschaftliche Konzeption eines gesellschaftlich vermittelten Lernens wird rezipiert, um Möglichkeiten für die wissenschaftlich fundierte Konstituierung und Entwicklung eines Lernens im Lebenszusammenhang zu erschließen, das an die gegenwärtige Komplexität, Flexibilität und Temporalität sozialer Wandlungsprozesse anzuschließen vermag. Deren Ertrag wird mit Blick auf die Überschreitung bisheriger wissenschafts- und lerntheoretischer Engführungen und auf die erwachsenenpädagogischen Entwicklungs- und Unterstützungsaufgaben eines lebensweltlich vermittelten Lernens ausgewertet. Als Ergebnis wird eine konzeptionelle Perspektive sichtbar, mit der sich Lernen im Lebenszusammenhang als systemisch-sozialstrukturelles Geschehen konstituieren, unterstützen und reflexiv entwickeln lässt. Exemplarische Ausblicke auf die Konturen sozialer Praktiken des Lernens zeigen, in welche Richtung diese Konzeption weiter zu denken wäre.
The theoretically possible stable conformers of free mn-15S2O3 maleonitrile-dithiacrown ether molecule were searched by means of a conformational study which consists of molecular dynamics and energy minimization calculations performed with MM2 force field and successive geometry optimization + frequency calculations performed first at B3LYP/3- 21G and then at B3LYP/6-31G(d) levels of theory. The obtained calculation results have clearly indicated that the free molecule in electronic ground state is very flexible and accordingly has many possible stable conformers of different conformational properties at room temperature; among them, the one having a macrocyclic ring structure in which all of the ether units oriented toward the center of the ring was determined the energetically most preferable conformer. In addition, the equilibrium geometrical parameters, vibrational normal modes and associated IR spectral data of the determined most stable three conformers of the molecule were calculated at B3LYP/6-31+G(d) and B3LYP/6-31++G(d,p) levels of theory. A successful assignment of the fundamental bands observed in the recorded experimental solid phase and solution phase IR spectra of the molecule was achieved in the light of the theoretical data obtained from these DFT calculations. To fit the calculated harmonic wavenumbers to the experimental ones, two different scaling procedures, referred to as "Scaled Quantum Mechanical Force Field (SQM FF) methodology" and "Scaling wavenumbers with empirical dual scale factors", were proceeded independently.
The Younger Dryas event, which began approximately 12,900 years ago, was a period of rapid cooling in the Northern Hemisphere, driven by large-scale reorganizations of patterns of atmospheric and oceanic circulation(1-3). Environmental changes during this period have been documented by both proxy-based reconstructions(3) and model simulations(4), but there is currently no consensus on the exact mechanisms of onset, stabilization or termination of the Younger Dryas(5-8). Here we present high-resolution records from two sediment cores obtained from Lake Krakenes in western Norway and the Nordic seas. Multiple proxies from Lake Krakenes are indicative of rapid alternations between glacial growth and melting during the later Younger Dryas. Meanwhile, reconstructed sea surface temperature and salinity from the Nordic seas show an alternation between sea-ice cover and the influx of warm, salty North Atlantic waters. We suggest that the influx of warm water enabled the westerly wind systems to drift northward, closer to their present-day positions. The winds thus brought relatively warm maritime air to Northern Europe, resulting in rising temperatures and the melting of glaciers. Subsequent input of this fresh meltwater into the ocean spurred the formation of sea ice, which forced the westerly winds back to the south, cooling Northern Europe. We conclude that rapid alternations between these two states immediately preceded the termination of the Younger Dryas and the permanent transition to an interglacial state.
Periodically forced ensemble of nonlinearly coupled oscillators : from partial to full synchrony
(2009)
We analyze the dynamics of a periodically forced oscillator ensemble with global nonlinear coupling. Without forcing, the system exhibits complicated collective dynamics, even for the simplest case of identical phase oscillators: due to nonlinearity, the synchronous state becomes unstable for certain values of the coupling parameter, and the system settles at the border between synchrony and asynchrony, what can be denoted as partial synchrony. We find that an external common forcing can result in two synchronous states: (i) a weak forcing entrains only the mean field, whereas the individual oscillators remain unlocked to the force and, correspondingly, to the mean field; (ii) a strong forcing fully synchronizes the system, making the phases of all oscillators identical. Analytical results are confirmed by numerics.
In diesem Handbuch steht die Nutzerorientierung im Vordergrund. Namhafte Autoren aus Wissenschaft und Praxis beschaeftigen sich in 16 Kapiteln mit Web-Suchmaschinen, die die Vorreiter hinsichtlich des sich veraendernden Nutzerverhaltens sind. Das bei Google und Co. erlernte Verhalten wird auf andere Suchsysteme uebertragen: die Website- Suche, die Intranet-Suche und die Suche in Spezialsuchmaschinen und Fachdatenbanken. Fuer alle Anbieter von Informationssystemen wird es zunehmend wichtig, einerseits die Arbeitsweise von Suchmaschinen zu kennen, andererseits mit dem Verhalten Ihrer Nutzer vertraut zu sein. Auf der Seite der Wissenschaftler werden Informatiker, Informationswissenschaftler, Medienwissenschaftler und Bibliothekswissenschaftler angesprochen. Fuer Entwickler bietet dieses Handbuch einen ueberblick ueber Moeglichkeiten fuer Suchsysteme, gibt Anregungen fuer Umsetzung und zeigt anhand von bestehenden Loesungen, wie eine Umsetzung aussehen kann. Fuer Entscheider, Rechercheure und Informationsvermittler bietet das Buch lesbare ueberblicksartikel zu relevanten Themenbereichen, auf deren Basis eine Strategie fuer individuelle Suchloesungen erarbeitet werden kann. Als dritte Praktiker gruppe sind u.a. Berater, Lehrer, Journalisten und Politiker zu nennen, die sich zu den wichtigsten Themen rund um die Suche informieren moechten.
Die Arbeit befasst sich auf der Ebene des Textes mit der Frage nach dem Textproduzenten der Buchform des Dramas. Gibt es im Drama ähnlich wie in der Epik oder Lyrik eine vermittelnde Instanz? Und sind die Nebentexte tatsächlich als Anweisungen oder nicht doch eher als Hinweise zu verstehen? Am Beispiel des expressionistischen Dramas "Geschehen" von August Stramm werden die vorherigen Überlegungen überprüft und für eine Textanalyse fruchtbar gemacht.
Accretionary orogens are considered major sites of formation of juvenile continental crust. In the central and southern Andes this is contradicted by two observations: siliciclastic fills of Paleozoic basins in the central Andean segment of the accretionary Terra Australis Orogen consist almost exclusively of shales and mature sandstones; and magmatic rocks connected to the Famatinian (Ordovician) and Late Paleozoic magmatic arcs are predominantly felsic and characterized by significant crustal contamination and strongly unradiogenic Nd isotope compositions. Evidence of juvenile crustal additions is scarce. We present laser ablation (LA)-ICPMS U-Pb ages and LA-MC-ICPMS Hf isotope data of detrital zircons from seven Devonian to Permian turbidite sandstones incorporated into a Late Paleozoic accretionary wedge at the western margin of Gondwana in northern Chile. The combination with Nd whole-rock isotope data permits us to trace the evolution of the South American continental crust through several Proterozoic and Paleozoic orogenic cycles. The analyzed detrital zircon spectra reflect all Proterozoic orogenic cycles representing the step-wise evolution of the accretionary SW Amazonia Orogenic System between 2.0 and 0.9 Ga, followed by the Terra Australis Orogen between 0.9 and 0.25 Ga. The zircon populations are characterized by two prominent maxima reflecting input from Sunsas (Grenville) age magmatic rocks (1.2-0.9 Ga) and from the Ordovician to Silurian Famatinian magmatic arc (0.52-0.42 Ga). Grains of Devonian age are scarce or absent from the analyzed zircon populations. The Hf isotopic compositions of selected dated zircons at the time of their crystallization (epsilon Hf-(T); T = 3.3-0.25 Ga) vary between -18 and +11. All sandstones have a significant juvenile component; between 20 and 50% of the zircons from each sedimentary rock have positive epsilon Hf-(T) and can be considered juvenile. The majority of the juvenile grains have Hf-depleted mantle model ages (Hf T-DM) between 1.55 and 0.8 Ga. the time of the Rondonia-San Ignacio and Sunsas orogenic events on the Amazonia craton. The corresponding whole-rock epsilon Nd-(T) values fot these same rocks are between -8 and -3 indicating a mixture of older evolved and juvenile sources. Nd-depleted mantle model ages (Nd T-DM*) are between 1.5 and 1.2 Ga and coincide broadly with the zircon Hf model ages. Our data indicate that the Paleo- and Mesoproterozoic SW Amazonia Orogenic System, and the subsequent Neoproterozoic and Paleozoic Terra Australis Orogen in the region of the central and southern Andes, developed following two markedly different patterns of accretionary orogenic crustal evolution. The SW Amazonia Orogenic System developed by southwestward growth over approximately 1.1 Ga through a combination of accretion of juvenile material and crustal recycling typical of the extensional or retreating mode of accretionary orogens. In contrast, the central Andean segment of the Terra Australis Orogen evolved from 0.9 to 0.25 Ga in the compressional or advancing mode in a relatively fixed position without the accretion of oceanic crustal units or large scale input of juvenile material to the orogenic crust. Here, recycling mainly of Mesoproterozoic continental crust has been the dominant process of crustal evolution. (C) 2009 Elsevier B.V. All rights reserved.
Tomato fruit and seed allergens were detected by IgE-immunoblotting using sera from 18 adult tomato-sensitized patients selected based on a positive history skin prick test (SPT) and specific Immunglobulin (Ig) E-levels. Isolated tomato seed total protein showed high SPT activity comparable or even higher than tomato fruit protein. For the molecular characterization of tomato seed allergens, a multidimensional protein fractionation strategy and LC-MS/MS was used. Two legumin- and vicilin-proteins were purified and showed strong IgE-reactivity in immunoblots. Individual patient sera exhibited varying IgE-sensitivity against the purified proteins. In silico structural modeling indicates high homology between epitopes of known walnut allergens and the detected IgE-crossreactive tomato proteins.
The acquisition of phonological alternations consists of many aspects as discussions in the relevant literature show. There are contrary findings about the role of naturalness. A natural process is grounded in phonetics; they are easy to learn, even in second language acquisition when adults have to learn certain processes that do not occur in their native language. There is also evidence that unnatural – arbitrary – rules can be learned. Current work on the acquisition of morphophonemic alternations suggests that their probability of occurrence is a crucial factor in acquisition. I have conducted an experiment to investigate the effects of naturalness as well as of probability of occurrence with 80 adult native speakers of German. It uses the Artificial Grammar paradigm: Two artificial languages were constructed, each with a particular alternation. In one language the alternation is natural (vowel harmony); in the other language the alternation is arbitrary (a vowel alternation depends on the sonorancy of the first consonant of the stem). The participants were divided in two groups, one group listened to the natural alternation and the other group listened to the unnatural alternation. Each group was divided into two subgroups. One subgroup then was presented with material in which the alternation occurred frequently and the other subgroup was presented with material in which the alternation occurred infrequently. After this exposure phase every participant was asked to produce new words during the test phase. Knowledge about the language-specific alternation pattern was needed to produce the forms correctly as the phonological contexts demanded certain alternants. The group performances have been compared with respect to the effects of naturalness and probability of occurrence. The natural rule was learned more easily than the unnatural one. Frequently presented rules were not learned more easily than the ones that were presented less frequently. Moreover, participants did not learn the unnatural rule at all, whether this rule was presented frequently or infrequently did not matter. There was a tendency that the natural rule was learned more easily if presented frequently than if presented infrequently, but it was not significant due to variability across participants.
We present an analysis of concentration switching times in microfluidic devices. The limits of rapid switching are analyzed based on the theory of dispersion by Taylor and Aris and compared to both experiments and numerical simulations. We focus on switching times obtained by photo-activation of caged compounds in a micro-flow (flow photolysis). The performance of flow photolysis is compared to other switching techniques. A flow chart is provided to facilitate the application of our theoretical analysis to microfluidic switching devices.
We study buckling instabilities of filaments in biological systems. Filaments in a cell are the building blocks of the cytoskeleton. They are responsible for the mechanical stability of cells and play an important role in intracellular transport by molecular motors, which transport cargo such as organelles along cytoskeletal filaments. Filaments of the cytoskeleton are semiflexible polymers, i.e., their bending energy is comparable to the thermal energy such that they can be viewed as elastic rods on the nanometer scale, which exhibit pronounced thermal fluctuations. Like macroscopic elastic rods, filaments can undergo a mechanical buckling instability under a compressive load. In the first part of the thesis, we study how this buckling instability is affected by the pronounced thermal fluctuations of the filaments. In cells, compressive loads on filaments can be generated by molecular motors. This happens, for example, during cell division in the mitotic spindle. In the second part of the thesis, we investigate how the stochastic nature of such motor-generated forces influences the buckling behavior of filaments. In chapter 2 we review briefly the buckling instability problem of rods on the macroscopic scale and introduce an analytical model for buckling of filaments or elastic rods in two spatial dimensions in the presence of thermal fluctuations. We present an analytical treatment of the buckling instability in the presence of thermal fluctuations based on a renormalization-like procedure in terms of the non-linear sigma model where we integrate out short-wavelength fluctuations in order to obtain an effective theory for the mode of the longest wavelength governing the buckling instability. We calculate the resulting shift of the critical force by fluctuation effects and find that, in two spatial dimensions, thermal fluctuations increase this force. Furthermore, in the buckled state, thermal fluctuations lead to an increase in the mean projected length of the filament in the force direction. As a function of the contour length, the mean projected length exhibits a cusp at the buckling instability, which becomes rounded by thermal fluctuations. Our main result is the observation that a buckled filament is stretched by thermal fluctuations, i.e., its mean projected length in the direction of the applied force increases by thermal fluctuations. Our analytical results are confirmed by Monte Carlo simulations for buckling of semiflexible filaments in two spatial dimensions. We also perform Monte Carlo simulations in higher spatial dimensions and show that the increase in projected length by thermal fluctuations is less pronounced than in two dimensions and strongly depends on the choice of the boundary conditions. In the second part of this work, we present a model for buckling of semiflexible filaments under the action of molecular motors. We investigate a system in which a group of motors moves along a clamped filament carrying a second filament as a cargo. The cargo-filament is pushed against the wall and eventually buckles. The force-generating motors can stochastically unbind and rebind to the filament during the buckling process. We formulate a stochastic model of this system and calculate the mean first passage time for the unbinding of all linking motors which corresponds to the transition back to the unbuckled state of the cargo filament in a mean-field model. Our results show that for sufficiently short microtubules the movement of kinesin-I-motors is affected by the load force generated by the cargo filament. Our predictions could be tested in future experiments.
Camus im Osten
(2009)
Albert Camus' 40. Todestag ist Anlaß, die literarische, kulturelle und politisch-soziale Bedeutung des Autors für die ehemals sozialistischen Länder zu dokumentieren. Camus' Interesse für diese Länder und die Unbestechlichkeit seines Urteils konnten von den oppositionellen Kräften als wirksame Unterstützung wahrgenommen werden; das belegen die Beiträge von acht LiteraturwissenschaftlerInnen, ÜbersetzerInnen und Kulturschaffenden, die an der Rezeption Camus' maßgeblich beteiligt waren und sind. Dabei wird deutlich, daß sich in der Auseinandersetzung mit Camus' Werk eine politische Haltung kundtat, die nicht selten eine Lebenshaltung und -entscheidung war.
Albert Camus in Rumänien
(2009)
We present observations from a continuous exposure of an ancient plate interface in the depth range of its former seismogenic zone in the central Alps of Europe related to Late Cretaceous-early Tertiary subduction and accretion of the South Penninic lower plate underneath the Adriatic upper plate. The material forming the exposed plate interface zone has experienced flow and fracturing over an extended period of time followed by syncollisional exhumation, thus reflecting a multistage evolution. Fabric formation and metamorphism, however, chiefly record the deformation conditions of the precollisional setting along the plate interface. We identify an unstable slip domain from pseudotachylytes occurring in the temperature range between 200 and 300 degrees C. This zone coincides with a domain of intense veining in the subduction melange with mineral growth into open cavities, indicating fast, possibly seismic, rupture. Evidence for transient near-lithostatic fluid pressure as well as brittle fractures competing with mylonitic shear zones continues into the region below the occurrence of pseudotachylytes, possibly reflecting a zone of conditionally stable slip. The zone above the unstable slip area is devoid of veins but displays ample evidence of fluid-assisted processes similar to the deeper zone: solution-precipitation creep and dehydration reactions in the melange matrix, hydration, and sealing of the base of the upper plate. Seismic rupture here is possibly expressed by ubiquitous localized deformation zones. We hypothesize that trenchward sealing of parts of the plate interface as well as reaction-enhanced destruction of upper plate permeability is an important component, localizing the unstable slip zone. This relation may result from the competition of the pervasive, presumably interseismic, pressure solution creep destroying permeability and building elevated fluid pressure until the strength threshold is reached with seismic failure.
The aim of the study was to investigate the influence of oral rehydration solutions (ORS) on milk clotting, abomasal pH, electrolyte concentrations, and osmolality, as well as on the acid-base status in blood of suckling calves, as treatment with ORS is the most common therapy of diarrhea in calves to correct dehydration and metabolic acidosis. Oral rehydration solutions are suspected to inhibit abomasal clotting of milk; however, it is recommended to continue feeding cow's milk or milk replacer (MR) to diarrheic calves to prevent body weight losses. Three calves with abomasal cannulas were fed MR, MR-ORS mixtures, or water-ORS mixtures, respectively. Samples of abomasal fluid were taken before and after feeding at various time points, and pH, electrolyte concentrations, and osmolality were measured. The interference of ORS with milk clotting was examined in vivo and in vitro. To evaluate the effects of ORS on systemic acid-base status, the Stewart variables strong ion difference ([SID]), acid total ([A(tot)]), and partial pressure of CO2 (pCO(2)) were quantified in venous blood samples drawn before and after feeding. Calves reached higher abomasal pH values when fed with MR-ORS mixtures than when fed MR. Preprandial pH values were re-established after 4 to 6 h. Oral rehydration solutions prepared in water increased the abomasal fluid pH only for 1 to 2 h. Oral rehydration solutions with high [SID3] ([Na+] + [K+] - [Cl-]) values produced significantly higher abomasal pH values and area under the curve data of the pH time course. Caseinomacropeptide, an indicator of successful enzymatic milk clotting, could be identified in every sample of abomasal fluid after feeding MR-ORS mixtures. The MR-ORS mixtures with [SID3] values >= 92 mmol/L increased serum [SID3] but did not change venous blood pH. Oral rehydration solutions do not interfere with milk clotting in the abomasum and can, therefore, be administered with milk. In this study, MR-ORS mixtures with high [SID3] values caused an increase of serum [SID3] in healthy suckling calves and may be an effective treatment for metabolic acidosis in calves suffering from diarrhea.
Mixed 1,2-Dümine-1,2-Dithiolate Ligand Complexes : Structure, Proberties and EPR Spectroscopy
(2009)
Savannah areas affected by human activities such as livestock keeping and agriculture are often characterized by shifts in landscape structuring, with a predominance of few(er) habitat types. This is typically accompanied by pronounced changes in the communities of ungulates. The aim of this study was to find out whether shifts in ungulate communities in Lake Mburo National Park (LMNP) are primarily predicted by an alteration in the composition of the preferred habitat types or if more complex interactions between habitat changes and the prevalence of ungulates occur. Monthly road counts were used to establish the number of eleven ungulate species in LMNP and adjacent unprotected Ankole Ranching Scheme. The common duiker (Sylvicapra grimmia campbelliae Gray, 1843) was found in more abundance in disturbed areas, while showing a significant change in habitat use. Common duiker tended to use the vegetation type otherwise used by the bushbuck (Tragelaphus scriptus dama Neumann, 1902). Our results support the claim that the occurrence of ungulates is not only directly affected by the availability of 'suitable' habitats, but behavioural plasticity and competitive exclusion also need to be considered.
En este documento se contrastan las observaciones de Humboldt acerca de los Incas en el Norte del actual Perú, en particular la Sierra de Piura, con las recientes investigaciones arqueológicas. Antes del tiempo de los Incas, la región fue habitada por grupos amazónicos que fueron los ancestros de los Jívaros, a cuyos descendientes Humboldt conoció en Tomependa en 1802, cerca al Amazonas. Por ello, también se realiza un balance de las investigaciones arqueológicas acerca de los Jívaros. Los planteamientos de Humboldt acerca de la Arquitectura Inca, su tipología de asentamientos, y su secuencia constructiva de la red de centros y caminos han sido evaluados mediante las recientes investigaciones arqueológicas y nos permiten plantear la vigencia de sus ideas y considerarlo como el fundador de la Arqueología científica en América. Finalmente se propone la revaloración de los sitios Inca y tramos de camino que él observó en 1802 y la creación de la Ruta de Humboldt.
Verfahrensrechtliche Klausuren sind oft Gegenstand des Pflichtfachstudiums, vor allem aber auch im Schwerpunktbereichsstudium "Zivilrechtspflege". Der vorliegende Band enthält Klausuren aus allen Gebieten des Zivilprozessrechts, also aus dem Erkenntnisverfahren sowie dem Zwangsvollstreckungsrecht. Die Bearbeitung der Klausuren soll der Aneignung des Stoffes, dessen Wiederholung und der Vorbereitung auf Prüfungen dienen. Die Autorin hat die Fälle konsequent nach der Ausbildungsrelevanz ausgewählt, behandelt Streitfragen und gibt Aufbautipps. Bisher fehlt es in diesem Bereich weitgehend an konsequent fallbezogener Ausbildungsliteratur. Der vorliegende Band enthält 20 Fälle mit ausführlichen Lösungen, vorangestellten Gliederungen und weiterführenden Hinweisen sowie eine Einführung in die Fallbearbeitungstechnik im Zivilprozessrecht. - das examensrelevante Wissen dargestellt in Klausurform - für das Pflichtfachstudium - zahlreiche didaktische Hinweise - - mit Anleitung zur Bearbeitung von ZPO-Klausuren - Partei- und Prozessfähigkeit - Streitgegenstand - Parteiwechsel - Leistungsklage - Mahnverfahren - Stufenklage - Widerklage Prozessvergleich- Zwangsvollstreckung
Many formal descriptions of DPLL-based SAT algorithms either do not include all essential proof techniques applied by modern SAT solvers or are bound to particular heuristics or data structures. This makes it difficult to analyze proof-theoretic properties or the search complexity of these algorithms. In this paper we try to improve this situation by developing a nondeterministic proof calculus that models the functioning of SAT algorithms based on the DPLL calculus with clause learning. This calculus is independent of implementation details yet precise enough to enable a formal analysis of realistic DPLL-based SAT algorithms.
Wie beständig ist der Mythos „Barack Obama“? Klar ist: Der neue Präsident tritt ein schweres Erbe an. Herausforderungen wie die Wirtschaftskrise, schwierige außen- und sicherheitspolitische Gegebenheiten und die Beziehungen zu Russland warten auf ihn. Der Autor, ein exzellenter Kenner der USA und ehemaliger Diplomat, beleuchtet die Situation der Vereinigten Staaten nach der Wahl.
Demografischer Wandel
(2009)
While several authors suggest that bushbuck (Tragelaphus scriptus Pallas) from tropical areas with an approximately bimodal rainfall pattern breed throughout the year, there is also a report of seasonal breeding in this species. In this study, we provide indirect evidence of seasonality in reproduction by analysing behavioural data (e.g. rates of mixed-sex sightings) in a population of bushbuck inhabiting an equatorial savannah ecosystem in western Uganda. Observation rates of mixed-sex sightings were correlated with rainfall patterns. We suggest that peaks in reproductive behaviour following the wet season may be advantageous if calves are born during the next wet season, when fresh vegetation is available.
Personalauswahl
(2009)
Untersuchung und Veränderung der Genexpression und Proteinstabilität in Plastiden höherer Pflanzen
(2009)
Background: The need for fast, specific and sensitive multiparametric detection methods is an ever growing demand in molecular diagnostics. Here we report on a newly developed method, the helicase dependent Onchip amplification (OnChip-HDA). This approach integrates the analysis and detection in one single reaction thus leading to time and cost savings in multiparametric analysis. Methods: HDA is an isothermal amplification method that is not depending on thermocycling as known from PCR due to the helicases' ability to unwind DNA double-strands. We have combined the HDA with microarray based detection, making it suitable for multiplex detection. As an example we used the Onchip HDA in single and multiplex amplifications for the detection of the two pathogens N. gonorrhoeae and S. aureus directly on surface bound primers. Results: We have successfully shown the OnChip-HDA and applied it for single- and duplex- detection of the pathogens N. gonorrhoeae and S. aureus. Conclusion: We have developed a new method, the OnChip-HDA for the multiplex detection of pathogens. Its simplicity in reaction setup and potential for miniaturization and multiparametric analysis is advantageous for the integration in miniaturized Lab on Chip systems, e.g. needed in point of care diagnostics.
Isothermal amplification technologies are emerging on the horizon that could have the potential to pose as alternatives to PCR in terms of sensitivity and ease of use. One of the most recent isothermal technologies is helicase- dependent amplification (HDA). This technology uses the helicase's capability to disrupt the hydrogen bonds of a Watson-Crick base pair in order to separate dsDNA. A denaturation step, as is used in PCR, is no longer required. This gives rise to new, less expensive and less complicated designs for point-of-care devices and 'Lab on Chip' systems. Helicase-dependent OnChip-amplification (OnChip-HDA) is a further step into this direction as it integrates the HDA technology with microarray technology and its power of multiplexing. This special report will give an overview on the HDA and OnChip-HDA technology, and its potential for point-of-care diagnostics.
In der molekularen Diagnostik besteht ein Bedarf an schnellen und spezifischen Testsystemen, die entweder für die Labordiagnostik oder in Point of Care-Umgebungen eingesetzt werden können. Um dieses Ziel zu erreichen, stehen die Miniaturisierung und Parallelisierung im Mittelpunkt des Forschungsinteresses. Die führende Methode im Bereich der DNA-Analytik ist derzeit die Realtime-PCR. Dieser Technologie sind hinsichtlich der Multiplexfähigkeit technologischen Hürden gesetzt, da derzeit nur eine Analyse von maximal vier Parametern parallel in einem Versuchsansatz erfolgen kann. Microarrays stellen hingegen die benötigten Voraussetzungen zur Verfügung, um als Werkzeuge für die Multiparameteranalyse in verschiedensten Anwendungsbereichen zu dienen. Ein Schwerpunkt dieser Arbeit war es, Multiplex-PCRs und diagnostische Microarrays zu entwickeln, die für analytische Fragestellungen eine schnelle und zuverlässige Multiparameteranalytik ermöglichen, um die bisherigen Einschränkungen aktueller Nachweisverfahren zu vermeiden. Als Anwendungen wurden zum einen ein Nachweissystem für acht relevante Geflügelpathogene zur Überwachung in der Geflügelzucht, zum anderen ein Nachweissystem zur Identifikation potentiell allergener Lebensmittelinhaltstoffe entwickelt. Neben der Entwicklung geeigneter PCR und Multiplex-PCR-Verfahren sowie spezifischer Microarrays für die Detektion der gesuchten Zielsequenzen stand auch die weiterführende Integration von DNA-Amplifikation und Microarray-Technologie im Fokus dieser Arbeit. Die OnChip-Amplifikation stellt eine Möglichkeit dar, um DNA-Analytik und Detektion in einem Reaktionsschritt zu integrieren. Entsprechend wurden die in der Arbeit entwickelten PCR- und Multiplex-PCR-Verfahren zum Nachweis potentieller allergener Lebensmittelinhaltsstoffe für die OnChip-Amplifikation adaptiert und Reaktionsbedingungen getestet, die eine Multiparameteranalyse auf dem Chip ermöglichen. Die entwickelten OnChip-PCR-Verfahren zeigten eine hohe Spezifität sowohl in Single- als auch in der Multiplex-OnChip-PCR. Eine Sensitivität von 10 Kopien bzw. <10ppm konnte in Single-OnChip-PCRs für den Nachweis allergener Lebensmittelinhaltsstoffe gezeigt werden. In Multiplex-OnChip-PCRs konnten 10-100ppm allergene Verunreinigungen spezifisch in unterschiedlichen Lebensmitteln nachgewiesen werden. Ein weiterer Schritt in Richtung einer möglichen Verwendung im Point of Care-Bereich stellt der Einsatz eines isothermalen Amplifikationsverfahrens dar. Vorteil eines solchen Verfahrens ist die Möglichkeit, auf das ansonsten benötigte Thermocycling zu verzichten. Dies vereinfacht eine Integration der OnChip-Amplifikation in mobile Analysegeräte oder Lab on Chip-Systeme und qualifiziert das Verfahren für den Einsatz in Point of Care-Umgebungen. In dieser Arbeit wurde eine noch junge isothermale Amplifikationsmethode, die helikase-abhängige Amplifikation (HDA), hinsichtlich ihrer Eignung für die Integration auf einem Microarray getestet. Hierfür konnte die bislang erste OnChip-HDA für Einzel- und Duplex-Nachweise von Pathogenen entwickelt werden.
Aus dem Inhalt: Einleitung Kapitel 1. Starke Gesetze der Grossen Zahlen 1. SGGZ unter Wachstumsbedingungen an die p-ten Momente 2. SGGZ für identisch verteilte Zufallsvariablen 3. SGGZ für Prozesse mit *-mixing-Eigenschaft Kapitel 2. Einführung zu diskreten (Sub-,Super-)Martingalen 1. Vorhersagbarkeit 2. gestoppte (Sub-,Super-)Martingale 3. Upcrossings 4. Konvergenzsätze 5. Doob-Zerlegung 6. Eine äquivalente Definition eines (Sub-)Martingals Kapitel 3. Martingale und gleichgradige Integrierbarkeit 1. Gleichmäßige(-f¨ormige,-gradige) Integrierbarkeit 2. gleichgradig integrierbare Martingale Kapitel 4. Martingale und das SGGZ Kapitel 5.”reversed“ (Sub-,Super-)Martingale 1. Konvergenzsätze Kapitel 6. (Sub-,Super-)Martingale mit gerichteter Indexmenge 1. Äquivalente Formulierung eines (Sub-)Martingals 2. Konvergenzsätze Kapitel 7. Quasimartingale,Amarts und Semiamarts 1. Konvergenzsätze 2. Riesz-Zerlegung 3. Doob-Zerlegung Kapitel 8. Amarts und das SGGZ Kapitel 9.”reversed“ Amarts und Semiamarts 1. Konvergenzsätze 2.”Aufwärts“- gegen ”Abwärts“-Adaptiertheit 3. Riesz-Zerlegung 4. Stabilitätsanalyse Kapitel 10. Amarts mit gerichteter Indexmenge 1. Konvergenzsätze 2. Riesz-Zerlegung Anhang A. zur Existenz einer Folge unabhängiger Zufallsvariablen B. Konvergenz