Refine
Has Fulltext
- yes (60)
Year of publication
- 2013 (60) (remove)
Document Type
- Postprint (60) (remove)
Language
- English (60) (remove)
Is part of the Bibliography
- yes (60)
Keywords
- ligand (3)
- Neuroenhancement (2)
- Sun: activity (2)
- adsorption (2)
- anomalous diffusion (2)
- aqueous-solution (2)
- carbon-dioxide (2)
- carbon-dioxide capture (2)
- metal-organic frameworks (2)
- models (2)
- morphology (2)
- phase-transitions (2)
- photoisomerization (2)
- Allozymes (1)
- Approximate Bayesian Computation (1)
- Arabidopsis thaliana (1)
- BMI (1)
- Bat rabies (1)
- Bimolecular Reaction (1)
- Bruck-Reilly extension (1)
- Bulk-mediated diffusion; (1)
- DNA cleavage (1)
- Ego-depletion (1)
- English as a seond language (1)
- Fano Factor (1)
- Gene Regulatory Network (1)
- German morphology (1)
- Germany (1)
- Greece (1)
- Leadership (1)
- Levy flights (1)
- MHD (1)
- Mediterranean Sea (1)
- Microsatellites (1)
- Mitochondrial DNA (1)
- OCP-Place (1)
- OTDR (1)
- Orchestia montagui (1)
- POL (1)
- Performance Information Use (1)
- Person-Organization Fit (1)
- Phylogeography (1)
- Prevention (1)
- Public Service Motivation (1)
- Reaction Rate Constant (1)
- Self-control (1)
- Stochastic Simulation (1)
- Sun: coronal mass ejections (CMEs) (1)
- Talitrids (1)
- Transformational Leadership (1)
- academic self-concept (1)
- adamantane (1)
- adolescence (1)
- age (1)
- aggressive cognitions (1)
- air-water-interface (1)
- alignment (1)
- alkynol cycloisomerization (1)
- amorphous polymers (1)
- amp (1)
- animal personalities (1)
- anionic polymerizations (1)
- anomalous Brownian motion (1)
- answer set programming (1)
- antibodies (1)
- arenediazonium salts (1)
- artificial language learning (1)
- arylboronic acids (1)
- aryldiazonium salts (1)
- aspect-ratio (1)
- assemblies (1)
- associative networks (1)
- atropisomerism (1)
- behavior (1)
- behavioural adaptations (1)
- bilingual processing (1)
- binding (1)
- biodiversity conservation (1)
- biomaterials (1)
- block-copolymers (1)
- boldness (1)
- boronic acid (1)
- building-blocks (1)
- burrow system (1)
- candidates (1)
- capacity (1)
- carbohydrate-based oxepines (1)
- carbonyl-compounds (1)
- cardiovascular magnetic resonance (1)
- catalyzed cross metathesis (1)
- catalyzed redox isomerization (1)
- cationic surfactants (1)
- chain azobenzene polymers (1)
- chemical-synthesis (1)
- chemoattractant (1)
- chemotaxis (1)
- circuits (1)
- clusters (1)
- codon usage (1)
- cohesive ends (1)
- common vole (1)
- community dynamics (1)
- compact groups (1)
- complex (1)
- complexes (1)
- compounds (1)
- continuous-flow (1)
- coordination polymer (1)
- copper(II) halide salts (1)
- coronal mass ejections (CMEs) (1)
- coronary angiography (1)
- coronary artery disease (1)
- cost-effectiveness (1)
- course timetabling (1)
- covalent organic framework (1)
- cross-cultural differences (1)
- crystals (1)
- cyclic-gmp (1)
- cytoskeleton (1)
- data analysis (1)
- data-storage (1)
- de-novo synthesis (1)
- decay dynamics (1)
- delivery (1)
- derivational morphology (1)
- dictyostelium-discoideum (1)
- diels-alder reaction (1)
- dilute aqueous-solutions (1)
- disordered media (1)
- doping (1)
- dye (1)
- dyes (1)
- dynamic HPLC (1)
- dynamic NMR (1)
- e-government (1)
- educational timetabling (1)
- efficient (1)
- electron-spin resonance (1)
- empathy (1)
- ena/vasp proteins (1)
- english past tense (1)
- entrepreneurship (1)
- epidemiology (1)
- ether methacrylates (1)
- exchange (1)
- faecal corticosterone metabolites (1)
- fall risk assessment (1)
- filaments (1)
- first language acquisition (1)
- flexibility (1)
- fractional dynamics (1)
- frame compliance (1)
- fulgides (1)
- functional annotation (1)
- gases (1)
- gender (1)
- gene family (1)
- gene ontology (1)
- general learning model (1)
- generalized Bruck-Reilly ∗-extension (1)
- generalized Langevin equation (1)
- genetic variation (1)
- genetic vectors (1)
- geomagnetic field (1)
- geomagnetic storm (1)
- glass-transition temperature (1)
- government-formation (1)
- grammatical judgments (1)
- grammaticalization (1)
- growth strategy (1)
- helping (1)
- heterogeneous catalysis (1)
- holographic diffraction gratings (1)
- hydrogen storage (1)
- impairment (1)
- implementation (1)
- in-situ (1)
- individual based modeling (1)
- infants (1)
- infection pathway (1)
- inflectional morphology (1)
- informed consent (1)
- inhomogeneous-media (1)
- innovation (1)
- innovation systems (1)
- instabilities (1)
- international comparison (1)
- interspecific interactions (1)
- intracellular-transport (1)
- intramolecular charge-transfer (1)
- intrinsic microporosity (1)
- ionic liquid (1)
- ionic liquids (1)
- ionothermal synthesis (1)
- landmark visibility (1)
- landscape genetics (1)
- langevin equation (1)
- late bilinguals (1)
- learning (1)
- life history (1)
- light (1)
- liquid-crystal precursors (1)
- living cells (1)
- long distance movement (1)
- lyssavirus (1)
- mRNA structure (1)
- magnetic fields (1)
- magnetic-properties (1)
- magnetosphere (1)
- masked priming (1)
- mass media (1)
- media violence (1)
- memory effects (1)
- metal nanoparticles (1)
- methods: numerical (1)
- migrant integration (1)
- mineralization beneath (1)
- mixed-matrix membranes (1)
- mixtures (1)
- mobile links (1)
- modified primers (1)
- modulation (1)
- molecular methods (1)
- molecular oxygen (1)
- molecular-dynamics (1)
- molecular-reorientation (1)
- molecular-structure (1)
- molecules (1)
- morphological priming (1)
- morphology processing (1)
- multiscale analysis (1)
- n-heterocyclic carbenes (1)
- n-isopropylacrylamide (1)
- naphthalenophanes (1)
- nest predation (1)
- nonword repetition (1)
- nucleation (1)
- o bond formation (1)
- olefin-metathesis (1)
- oligo(ethylene glycol) methacrylate (1)
- optical sensing (1)
- orthophosphates (1)
- oscillations (1)
- osmotic-stress (1)
- pace-of-life (1)
- palladium catalyst (1)
- paramagnetic-resonance (1)
- parental pressure (1)
- past tense (1)
- pedestrian navigation (1)
- peer pressure (1)
- phenanthrenes (1)
- phenotypic plasticity (1)
- phonotactic probability (1)
- phonotactics (1)
- phosphorylation (1)
- photo-dehydro-Diels-Alder reaction (1)
- photochemical synthesis (1)
- photoinduced nonadiabatic dynamics (1)
- polycationic monolayer (1)
- polymerase chain reaction (1)
- polysemy (1)
- postural stability (1)
- pre-lexical processing (1)
- prediction (1)
- pressure (1)
- prosocial behavior (1)
- prosocial media (1)
- protein interactions (1)
- protein-kinase inhibitors (1)
- pseudo-differential operators (1)
- public policy (1)
- random-walks (1)
- ratchet transport (1)
- recombinant Escherichia coli (1)
- reduction (1)
- reference database (1)
- reference groups (1)
- reference proteomes (1)
- regular monoid (1)
- regulatory environment (1)
- research ethics (1)
- resistance training (1)
- responsive polymers (1)
- restriction enzymes (1)
- resultative sentences (1)
- ring-closing metathesis (1)
- ring-closure (1)
- ruthenium carbene (1)
- school (1)
- scintigraphy (1)
- second language (1)
- selectivity (1)
- semantic change (1)
- semiempirical methods (1)
- seniors (1)
- sensitivity (1)
- sentence repetition (1)
- separation (1)
- sets (1)
- shallow structure hypothesis (1)
- shape (1)
- shrews (1)
- silver nanowires (1)
- single-particle tracking (1)
- small mammals (1)
- social behavior (1)
- social comparison (1)
- social media analytics (1)
- solvatochromic fluorophore (1)
- solvent (1)
- speaking children (1)
- species coexistence (1)
- spectral exponent (1)
- spectroscopy (1)
- speech (1)
- speech segmentation (1)
- square planar (1)
- starch synthases (1)
- state (1)
- states (1)
- stereoselective-synthesis (1)
- stochastic (1)
- stochastic processes (1)
- stress (1)
- stress response (1)
- subjectification (1)
- substituted stilbenes (1)
- sulfoxides (1)
- surface (1)
- surface-plasmon resonance (1)
- surveillance (1)
- system (1)
- systems biology (1)
- temperature (1)
- temperature phase (1)
- tetrachlorocuprate(II) salts (1)
- the English progressive construction (1)
- thermochemistry (1)
- thermometer (1)
- thermoresponsive polymers (1)
- thin-films (1)
- to-coil transition (1)
- tracking (1)
- trans-stilbenes (1)
- transcript level (1)
- transduction (1)
- transformation (1)
- translation (1)
- triangular-[4] phenylene (1)
- usability testing (1)
- user-centred design (1)
- verb classes (1)
- violent media (1)
- viscoelasticity (1)
- voles (1)
- words (1)
- zeolitic imidazolate frameworks (1)
- zinc (1)
- π -inverse monoid (1)
Institute
- Institut für Chemie (20)
- Mathematisch-Naturwissenschaftliche Fakultät (14)
- Humanwissenschaftliche Fakultät (7)
- Institut für Biochemie und Biologie (6)
- Department Sport- und Gesundheitswissenschaften (3)
- Department Psychologie (2)
- Institut für Anglistik und Amerikanistik (2)
- Wirtschafts- und Sozialwissenschaftliche Fakultät (2)
- Fachgruppe Volkswirtschaftslehre (1)
- Institut für Germanistik (1)
Intracellular photoactivation of caged cGMP induces myosin II and actin responses in motile cells
(2013)
Cyclic GMP (cGMP) is a ubiquitous second messenger in eukaryotic cells. It is assumed to regulate the association of myosin II with the cytoskeleton of motile cells. When cells of the social amoeba Dictyostelium discoideum are exposed to chemoattractants or to increased osmotic stress, intracellular cGMP levels rise, preceding the accumulation of myosin II in the cell cortex. To directly investigate the impact of intracellular cGMP on cytoskeletal dynamics in a living cell, we released cGMP inside the cell by laser-induced photo-cleavage of a caged precursor. With this approach, we could directly show in a live cell experiment that an increase in intracellular cGMP indeed induces myosin II to accumulate in the cortex. Unexpectedly, we observed for the first time that also the amount of filamentous actin in the cell cortex increases upon a rise in the cGMP concentration, independently of cAMP receptor activation and signaling. We discuss our results in the light of recent work on the cGMP signaling pathway and suggest possible links between cGMP signaling and the actin system.
With the present theoretical study of the photochemical switching of E-methylfurylfulgide we contribute an important step towards the understanding of the photochemical processes in furylfulgide-related molecules. We have carried out large-scale, full-dimensional direct semiempirical configuration-interaction surface-hopping dynamics of the photoinduced ring-closure reaction. Simulated static and dynamical UV/Vis-spectra show good agreement with experimental data of the same molecule. By a careful investigation of our dynamical data, we were able to identify marked differences to the dynamics of the previously studied E-isopropylfurylfulgide. With our simulations we can not only reproduce the experimentally observed quantum yield differences qualitatively but we can also pinpoint two reasons for them: kinematics and pre-orientation. With our analysis, we thus offer straightforward molecular explanations for the high sensitivity of the photodynamics towards seemingly minor changes in molecular constitution. Beyond the realm of furylfulgides, these insights provide additional guidance to the rational design of photochemically switchable molecules.
The time-dependent approach to electronic spectroscopy, as popularized by Heller and coworkers in the 1980's, is applied here in conjunction with linear-response, time-dependent density functional theory to study vibronic absorption, emission and resonance Raman spectra of several diamondoids. Two-state models, the harmonic and the Condon approximations, are used for the calculations, making them easily applicable to larger molecules. The method is applied to nine pristine lower and higher diamondoids: adamantane, diamantane, triamantane, and three isomers each of tetramantane and pentamantane. We also consider a hybrid species “Dia = Dia” – a shorthand notation for a recently synthesized molecule comprising two diamantane units connected by a C[double bond, length as m-dash]C double bond. We resolve and interpret trends in optical and vibrational properties of these molecules as a function of their size, shape, and symmetry, as well as effects of “blending” with sp2-hybridized C-atoms. Time-dependent correlation functions facilitate the computations and shed light on the vibrational dynamics following electronic transitions.
We consider diffusion processes with a spatially varying diffusivity giving rise to anomalous diffusion. Such heterogeneous diffusion processes are analysed for the cases of exponential, power-law, and logarithmic dependencies of the diffusion coefficient on the particle position. Combining analytical approaches with stochastic simulations, we show that the functional form of the space-dependent diffusion coefficient and the initial conditions of the diffusing particles are vital for their statistical and ergodic properties. In all three cases a weak ergodicity breaking between the time and ensemble averaged mean squared displacements is observed. We also demonstrate a population splitting of the time averaged traces into fast and slow diffusers for the case of exponential variation of the diffusivity as well as a particle trapping in the case of the logarithmic diffusivity. Our analysis is complemented by the quantitative study of the space coverage, the diffusive spreading of the probability density, as well as the survival probability.
A Co(II)–imidazolate-4-amide-5-imidate based MOF, IFP-5, is synthesized by using an imidazolate anion-based novel ionic liquid as a linker precursor under solvothermal conditions. IFP-5 shows significant amounts of gas (N2, CO2, CH4 and H2) uptake capacities. IFP-5 exhibits an independent high spin Co(II) centre and antiferromagnetic coupling.
A rare example of in situ linker generation with the formation of soft porous Zn- and Co-MOFs (IFP-9 and -10, respectively) is reported. The flexible ethoxy groups of IFP-9 and -10 protrude into the 1D hexagonal channels. The gas-sorption behavior of both materials for H2, CO2 and CH4 showed wide hysteretic isotherms, typical for MOFs having a flexible substituent which can give rise to a gate effect.
This article presents the results of a study on the interpretation and acceptance of adjectival resultatives of German children between 6 and 9 years of age and adults. These results brought to light significant differences, due to age, in the interpretation and acceptance of these resultatives, that is to say, sentences with an adjective in the final position. The youngest participants were prone to accept ungrammatical sentences by assigning a resultative meaning. The ungrammaticality of the sentences in question was not due to semantic inconsistencies but to violations of the selectional properties of verbs, as for instance in *die Kinder erschrecken die Katze ängstlich ‘the children frighten the cat scared’. In contrast, the adults rejected or amended those sentences. The conclusion is (a) that the children seemed to rely on the sentence structure as a primary cue to compute the meaning of an utterance and (b) that, in contrast with adults, the youngest children in particular had not yet learned the relevant semantic properties of verbs that determine the selectional restrictions and thus the syntactic options of verbs. This means that differences in interpretation and acceptance of sentences are due to differences in knowledge of semantic verb properties between adults and children. The relevant semantic knowledge increases in gradual stages during language acquisition.
In this article, it will be argued that the concept of functional layering – an extension of Hopper’s (1991) concept of layering – can be fruitfully applied to understand the mechanisms behind the sometimes large and messy looking synchronic picture of diverse meanings which one and the same construction can fulfill at a particular point in time. The concept will be used to account for the meaning spectrum of the present-day English progressive, which, it will be argued, no monosemic approach to date can account for. Taking a look at the diachrony of the construction will help to reveal that the various “exceptions” found in the use of the progressive can be understood as reflections of different stages in its development. Older, less grammaticalized or less well-defined usage patterns thus often survive in certain restricted niches next to the newer, more grammaticalized or more clear-cut functions, representing different diachronic layers. In addition to this diachronic motivation for synchronic meaning variety, the article will also address the crucial question of how a present-day hearer of a progressive form is able to decode the specific meaning intended by the speaker based on contextual clues. The article ends with some suggestions for further applications of the concept of functional layering.
Deep into the second half of the twentieth century the traditionalist definition of India as a country of villages remained dominant in official political rhetoric as well as cultural production. In the past two decades or so, this ruralist paradigm has been effectively superseded by a metropolitan imaginary in which the modern, globalised megacity increasingly functions as representative of India as a whole. Has the village, then, entirely vanished from the cultural imaginary in contemporary India? Addressing economic practices from upper-class consumerism to working-class family support strategies, this paper attempts to trace how ‘the village’ resurfaces or survives as a cultural reference point in the midst of the urban.