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Recent advances in microscopy have led to an improved visualization of different cell processes. Yet, this also leads to a higher demand of tools which can process images in an automated and quantitative fashion. Here, we present two applications that were developed to quantify different processes in eukaryotic cells which rely on the organization and dynamics of the cytoskeleton.. In plant cells, microtubules and actin filaments form the backbone of the cytoskeleton. These structures support cytoplasmic streaming, cell wall organization and tracking of cellular material to and from the plasma membrane. To better understand the underlying mechanisms of cytoskeletal organization, dynamics and coordination, frameworks for the quantification are needed. While this is fairly well established for the microtubules, the actin cytoskeleton has remained difficult to study due to its highly dynamic behaviour. One aim of this thesis was therefore to provide an automated framework to quantify and describe actin organization and dynamics. We used the framework to represent actin structures as networks and examined the transport efficiency in Arabidopsis thaliana hypocotyl cells. Furthermore, we applied the framework to determine the growth mode of cotton fibers and compared the actin organization in wild-type and mutant cells of rice. Finally, we developed a graphical user interface for easy usage. Microtubules and the actin cytoskeleton also play a major role in the morphogenesis of epidermal leaf pavement cells. These cells have highly complex and interdigitated shapes which are hard to describe in a quantitative way. While the relationship between microtubules, the actin cytoskeleton and shape formation is the object of many studies, it is still not clear how and if the cytoskeletal components predefine indentations and protrusions in pavement cell shapes. To understand the underlying cell processes which coordinate cell morphogenesis, a quantitative shape descriptor is needed. Therefore, the second aim of this thesis was the development of a network-based shape descriptor which captures global and local shape features, facilitates shape comparison and can be used to evaluate shape complexity. We demonstrated that our framework can be used to describe and compare shapes from various domains. In addition, we showed that the framework accurately detects local shape features of pavement cells and outperform contending approaches. In the third part of the thesis, we extended the shape description framework to describe pavement cell shape features on tissue-level by proposing different network representations of the underlying imaging data.
Planstadt Doberlug
(2020)
The paper investigates the question of sustainability of capacity building initiatives by reporting about the multiplication training in the frame of DIES NMT Programme on quality assurance in Uganda and how it could make use of the social capital within the existing quality assurance network to sustain and address challenges during its implementation. The purpose of the article is to explore the nature of networking (social and institutional) which was established by the Ugandan Universities Quality Assurance Forum (UUQAF) and share the strategies used in this training experience for future sustainable capacity building training initiatives in emerging economies. The paper employed a qualitative research method to describe and analyse the training framework based on primary and secondary documents.
Higher education institutions in Guinea face many challenges, including reporting responsibilities, globalisation, and massification. Institutional evaluations of higher education and research institutions in 2013 could not initiate the implementation of change processes within the institutions. Recently, however, various initiatives have been started to change this situation with the purpose to sensitise and raise awareness and capabilities for quality assurance structures in Guinean HEIs. So far, the emphasis has been put on quality enhancement in higher education, especially on teaching evaluation, curriculum development, as well as on establishing quality assurance structures. This article gives an overview of the state of play and takes stock of the activities that have been initiated to set up quality assurance mechanisms in higher education and research institutions, and presents perspectives for further development of the quality approach in Guinea. The project ‘Quality Assurance Multiplication 2017-2018’ serves as an example to describe approaches and activities in setting up stable quality assurance structures, and to strengthen and raise awareness for a ‘quality culture’.
Les établissements d’enseignement supérieur en Guinée sont confrontés à de nombreux défis, notamment les responsabilités en matière de rapports, la mondialisation et la massification. Les évaluations institutionnelles des établissements d’enseignement supérieur (EES) et de recherche en 2013 n’ont pas permis d’initier la mise en oeuvre des processus de changement au sein des établissements. Récemment, diverses initiatives ont été lancées pour changer cette situation dans le but de sensibiliser et de renforcer la prise de conscience et les capacités des structures d’assurance qualité dans les EES guinéennes. Jusqu’à présent, l’accent a été mis sur l’amélioration de la qualité dans l’enseignement supérieur, en particulier sur l’évaluation de l’enseignement, l’élaboration des programmes d’études, ainsi que sur la mise en place de structures d’assurance qualité. Cet article donne un aperçu de l’état des lieux et fait le point sur les activités qui ont été lancées pour mettre en place des mécanismes d’assurance qualité dans les établissements d’enseignement supérieur et de recherche, et présente les perspectives de développement de l›approche qualité en Guinée. Le projet «Multiplication de l’assurance qualité 2017 – 2018» sert d’exemple pour décrire les approches et les activités de mise en place de structures stables d’assurance qualité, et pour renforcer et sensibiliser à une «culture de la qualité».
Whilst providing a framework for learning and scientific emancipation, a proposal writing training is confronted with various organisational and didactic challenges, which influence the achievement of the set training objectives. Based on observations made during the workshops for proposal writing organised in Kinshasa, Democratic Republic of Congo, as part of the NMT Programme, the article raises two main questions: (a) How could these challenges be overcome and successfully addressed in the training? (b) What is the level of learning outcomes of the participants at the end of the training? The article shows that the success of the training lays in the relevance of the employed training approaches. The use of a participatory approach encouraged constructive exchanges between participants, trainers, and experts, and enabled all participants to finalise coherent projects to apply for national and international funding.
Mise en oeuvre de l’atelier d’écriture des projets de recherche en République démocratique du Congo
(2020)
Tout en offrant un cadre d’apprentissage et d’émancipation scientifique, l’atelier d’écriture des projets oppose différents défis, d’ordre organisationnel et didactique, dont les approches influent sur son déploiement et sur l’atteinte des objectifs assignés. Comment s’y prendre pour contourner ces défis et accomplir avec succès l’implémentation de la formation proposée ? Quelle en est l’incidence sur la qualité des acquisitions des participants au terme de la formation ? Le présent article répond à ces questions, partant des observations faites lors des formations organisées à Kinshasa (République démocratique du Congo) dans le cadre du programme National Multiplication Training (NMT). Il en ressort que le succès d’un atelier réside dans la pertinence des approches mises en oeuvre. Le recours à l’approche participative a favorisé les échanges constructifs entre participants, formateurs et experts, et a permis à tous les participants de finaliser des projets cohérents, pour postuler aux financements nationaux et internationaux.
This article collected the results of a qualitative study focused on Colombian Higher Education Institutions’ representatives partaking in the training ‘Internationalisation for Peacebuilding 2018’. The selected Higher Education Institutions and representatives were all located in regions acutely affected by the Colombian armed conflict, now experiencing multifaceted challenges and opportunities in a post-conflict scenario. Interviews with participants of the training were conducted to analyse the skills acquired and to identify possible improvements brought about by the training at the institutions. The article further identifies specific needs of the institutions, to be taken into account for future courses on internationalisation for higher education institutions.
During the National Multiplication Training in Kenya in 2018, participants raised concerns about attrition, completion rates and quality of PhD programmes in Kenya’s public universities. This led the authors of this article to further examine the question of PhD completion rates. Available data underlined that PhD students across various disciplines in Kenya’s public universities take unnecessarily long to complete their studies due to a myriad of factors that are related to their supervisors, university guidelines for post-graduate studies, or the students themselves. This article examines inertia areas along the PhD training pathway at three public universities in Kenya and provides suggestions on structural and operational changes universities must make to shorten completion periods.
Deans at Institutions of Higher Education are seldom recipients of effective or specific professional management training, institutional mentorship, and coaching despite an increasing demand on them to play a more dynamic leadership role in the face of ever-changing local and global challenges. To address this deficiency, the inaugural Malaysian Chapter of the International Deans’ Course (MyIDC) was held in three parts over 2019 and 2020. In this paper, findings related to feedback on the programme are presented and discussed. Responses from the participants from two sets of surveys, and written feedback provided by two IDC international trainers involved in MyIDC were analysed. These reveal potential areas of improvement for the forthcoming MyIDC programme, such as in terms of planning and organisation, duration, content, and delivery. The article explores the lessons learnt from the MyIDC 2019/2020 training programme and discusses the improvements that can be made arising from the feedback received.
The higher education structure in Malaysia has experienced significant changes since the implementation of the Private Higher Educational Institutions Act of 1996. The unprecedented expansion of the higher education sector and the increasing autonomy conferred to universities have created a huge demand for competent university leadership that supports the development of higher education in Malaysia. This article discusses the very first national multiplication training in Malaysia in 2014 and analyses such out-comes as the identification of good practices for future initiatives and applications in university leadership training.
Wolfenstein: The New Order
(2020)
Silent Hill 2
(2020)
Papers, Please
(2020)
Mass Effect
(2020)
Grand Theft Auto V
(2020)
Unter den prägenden Eindrücken, die der junge A. v. Humboldt empfing, steht an erster Stelle seine Beziehung zu Georg Forster, dem Weltumsegler, Schriftsteller und späteren Revolutionär. Hier wird neben der Geschichte ihrer Beziehungen vor allem Forsters Bedeutung für Humboldt behandelt. Forsters Schriften und seine Persönlichkeit beeindruckten Humboldt. Er sah in dem Forscher ein Vorbild bei der Beobachtung und dem Vergleich geographischer, naturkundlicher und sozialer Erscheinungen, aber auch im Bestreben, Gesetzmäßigkeiten aufzudecken. Forster regte Humboldt an, in verschiedene Wissenschaftsgebiete einzudringen; in Humboldts literarischen Beschreibung der Natur, der Landschaft und ihrer Bewohner wird der Einfluss des Älteren deutlich. Forster war einer der wichtigsten Vertreter progressiven politischen Denkens und der Parteinahme für die Ideale der Französische Revolution, mit dem der junge Humboldt in Berührung kam. So beeinflusste ihn auch Forsters Haltung gegen Sklaverei und Rassendiskriminierung. Humboldt identifizierte sich nie mit dem Jakobiner Forster, bekannte sich aber öffentlich zu seinem Freund und Lehrer, indem er die „gleiche Richtung politischer Meinungen“ hervorhob.
Im Jahre 1789 hatte Alexander von Humboldt als Student in Göttingen mit großem Enthusiasmus ein Manuskript zur „Weberei der Alten“ verfasst. Es war das Ziel seiner Studie, die Technologie und die Terminologie der antiken Weberei zu erfassen und beide Gebiete vereint darzustellen. Dieses Manuskript ist nicht veröffentlicht worden und gilt als verschollen. Alexander von Humboldt hatte offenbar neue Erkenntnisse gewonnen, denen er so große Bedeutung beimaß, dass er den Verlust seines Manuskriptes noch über 50 Jahre nach dessen Abfassung bedauerte. Humboldt benennt glücklicherweise in überlieferten Briefen verschiedene Grundgedanken seiner damaligen Arbeit. In der vorliegenden Studie wird unter Einbeziehung aktueller technikhistorischer Erkenntnisse nachgewiesen, dass der junge Alexander von Humboldt das für alle Webtechniken gültige Prinzip in seinen Grundzügen erkannt hatte.
Though Humboldt’s travels to the Americas have been analyzed from a wide range of viewpoints, there are specific aspects that still await further investigation. Little is written about Humboldt in the field, specifically how he moved between different locations and simultaneously measured and mapped places and phenomena. The aim of this article is to discuss the triad movement-measure-ment-map that led to the development of specific practices of knowledge building on the move. Humboldt’s search for the connections between the watersheds of the Orinoco and the Amazon rivers and the resulting maps and drawings are used as an example to point out his cartographic impulse in his quest to understand and explain the physical world.
In dem vorliegenden Beitrag geht der Verfasser von seinen Gesprächen aus, die er mit seinem Kollegen Michaeler in der Zeit von 1976 bis 1985 an der Universidad Incca de Colombia führen konnte. Dabei bezieht er die ihm – von Michaeler vor seinem Tod – übergebenen biografischen Daten mit ein. Insgesamt sollen die Ausführungen zum Weiterdenken anregen. Der Beitrag geht von der vielfältigen klimatischen und archäologischen Landschaft Kolumbiens aus und verbindet dies mit der damaligen Wissenschaftskonzeption an der Universidad Incca de Colombia. In diesem Kontext wird u. a. auf das Werk von Ernst Bloch „Das Prinzip Hoffnung“ und die Arbeit von Hans Jonas „Das Prinzip Verantwortung“ Bezug genommen. Für Michaeler waren die Werke der Brüder Humboldt, die Schrift Kants „Zum ewigen Frieden“, die Dialektik Hegels und die Gesellschaftstheorie von Marx in der Universitätsausbildung unverzichtbar.
Humboldts Eskorte
(2020)
Auf seiner Russlandexpedition von 1829 wurde Alexander von Humboldt fast durchgängig von Sicherheitskräften der Regierung begleitet. Die Forschung wies dieser Eskorte bisher vor allem eine Kontrollfunktion zu. Im Folgenden wird gezeigt, dass Humboldts bewaffnete Begleiter wahrscheinlich weniger der Überwachung, als der Absicherung seiner Expedition dienten. Der Artikel wirft dafür einen Blick auf die Sicherheitslage im Umfeld der Russlandreise, die Eskorte an sich sowie ihre letztendlich eng begrenzten Möglichkeiten zur Kontrolle des Wissenschaftlers. An Material stehen dafür unter anderem Humboldts Reisekorrespondenz, der Reisebericht seines Gefährten Gustav Rose und die erst jüngst veröffentlichten Tagebücher Christian Gottfried Ehrenbergs zur Verfügung.
L’article contient l’édition critique d’un mémoire d’Alexander von Humboldt, intitulé: «Considérations sur l’atmosphère des tropiques, regardée comme objet de la pathologie chimique». Le texte a été écrit à Cuba, en 1801. Il fait partie d’un groupe de manuscrits, relatifs à la qualité de l’air dans les tropiques et aux maladies qui en découlent, portant un titre général: «C’est mon cahier de la Havanne intitulé sur la salubrité de l’air». Or A. v. Humboldt partageait alors les vues miasmatiques et il voyait, dans la qualité de l’air, l’origine des maladies que l’on dit aujourd’hui «infectieuses». L’accent y est posé sur la fièvre jaune qui occupait une place particulière dans l’horizon intellectuel et politique du début du XIXe siècle. Reste à ajouter que Humboldt se montre ici comme l’un des précurseurs de l’écologie moderne.
Brothers: A Tale of Two Sons
(2020)
Sängers Glück
(2020)
The German singer-songwriter Reinhard Mey, although not pretending to be a second Orpheus, nevertheless appears to be very familiar with classical myth.
„An Herrn Prof. A. Wlosok“
(2020)
In contrast to other European countries, female professors of Classical Philology have been severely underrepresented in Germany. This article wants to shed light on Antonie Wlosok (1930–2013), the first or second woman to hold a Chair of Classical Philology in Germany. How can Wlosok’s work at Johannes Gutenberg University Mainz be described, considering especially the very male-dominated academic world? Based on testimonials from the university archives and selected publications, this essay aims to give insights to this question, highlighting current debates about women in academia.
Lotte Eisner
(2020)
Lotte Eisner (1896–1983) is without doubt one of the most important early film critics and pioneers of film history. In the history of Classical Studies, however, she plays no role. She is not even mentioned in the relevant scholarly books or articles, although she received a doctorate degree in Classical Archaeology. But it is worth taking a closer look at this relatively short phase of her life. The following lines are to be understood as a sketch of her specific ‘archaeological’ view of German Expressionist silent films. Lotte Eisner herself comments on this in her autobiography.
This article analyses, as an example of the advertising of cosmetic products, a campaign launched by the US-American company “Johnson Soap” for their product, the facial soap “Palmolive”. Examining its ads of 1911 in which certain ancient exempla are employed, it becomes clear that the Palmyrene queen Zenobia and with her the semi-historical Semiramis and the more mythical Dido are aligned to the “1001 Nights” character Scheherazade. Since they are jointly labelled as “historically famous oriental queens” and because of the reference to Zenobia’s white skin, they fall into the fantasy of fair-skinned harem women and evoke thoughts of all the pleasures and comforts of the luxurious Orient. To the modern female customer of 1900 (well steeped in the knowledge of those ancient characters) Zenobia and the other exempla should serve as celebrities worth emulating. Above all they are deemed to be beautiful, and experts in cosmetics which would guarantee the effect of the product they are standing for. A finding that proves to be valid even in an advertising concept of today for the Syrian-German “Zhenobya-soap”.
Träume statt Theurgie
(2020)
In his work De insomniis (On Dreams), Synesios adopts a rather critical view of theurgy, resembling Porphyry’s attitude; his wording shows polemical exaggeration. His insistence on the usefulness of dream revelation for hunting might be read as a (not too serious) claim to the divine inspiration of his work κυνηγετικαί.
Epistula 46 is an invitation, written under the name of Paula and Eustochium, for Marcella to go to Bethlehem, by all means with the aim to stimulate positive interest in the Holy Land for a wider public and to inspire the urge to travel and sojourn. The narrative defines pilgrimage not only through biblical references but also familiarizes it through references to ancient pagan practices and pagan literature and makes it compatible with the lifestyle of Rome’s urban elites. While biblical references predominantly propagate Palestine’s spiritual appeal as a site of centuries-long salvation events, references to the classics – often combined with the expression or the stimulation of emotions – put the region’s social and intellectual appeal to the fore. The use of pagan literature, in which the traditions of educational travel of a cosmopolitan elite, the social utopia of aristocratic recessus, and not least the pleasure of otium aestheticised through literature are prefigurated, shapes Palestine in particular fashion as a place of longing. Especially the appeal of Bethlehem thus only forms through the combination of spiritual-intellectual visio and emotionally attractive social utopia, through conjunction of spelunca Christi and bucolic idyll.
In Martial’s epigrams Silius Italicus is portrayed as a man of learning, author of the Punica and admirer of Vergil’s works, but also as a public figure and a former consul of Rome. My paper focuses on the epigrams devoted to the ‘political’ Silius, and suggests to relate them mainly to a certain stage in Silius Italicus’ life and to a specific communication strategy.
This paper analyzes a specific section of Martial’s Apophoreta (Book 14), the ‘list’ of fourteen literary works that the poet-persona suggests to the reader as potentially suitable presents to give to friends on the occasion of the Saturnalia. It focuses strictly on the literary aspects of the poems and their underlying carnivalesque poetics. This includes an assessment of the logic of the poems’ arrangement and alleged inconsistencies. It is suggested that the section be read as a complex statement of Martial’s on various works and genres of Greek and Roman literature. The last couplet of the section (14.196), a certain Calvus’ work ‘On the use of cold water’ (De aquae frigidae usu), which is unidentifiable, receives particular attention, for previous scholarship has wasted a lot of ink on guessing what kind of work this may have been, thereby losing touch with the rich (meta-)poetics the couplet actually conveys.