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The paper presents a production experiment investigating the phonetic parameters speakers employ to differentiate Yes-No questions from string-identical statements in Akan, a West-African two-tone Kwa language. Results show that, in comparison to the statement, speakers use a higher pitch register throughout the utterance as a global parameter, and falling f0, longer duration and higher intensity as local parameters on the final syllable of the Yes-No question. Further, two perception experiments (forced-choice identification and gating) investigate the perceptual relevance of the global parameter and the local final parameters. Results show that listeners cannot assess the higher pitch register information to identify the mode of a sentence early on. Rather, identification takes place when the local phonetic parameters on the final vowel are available. The findings point to the superiority of language-specific cues in sentence mode perception. It is suggested that Akan uses a low boundary tone that associates with the right edge of the intonation phrase (L%) in Yes-No questions. The results are discussed from the point of view of question intonation typology in African languages. It is argued that a classification along the lines of functionally relevant cues is preferable to an impressionistic analysis.
Stimulating numbers
(2018)
Finger counting is one of the first steps in the development of mature number concepts. With a one-to-one correspondence of fingers to numbers in Western finger counting, fingers hold two numerical meanings: one is based on the number of fingers raised and the second is based on their ordinal position within the habitual finger counting sequence. This study investigated how these two numerical meanings of fingers are intertwined with numerical cognition in adults. Participants received tactile stimulation on their fingertips of one hand and named either the number of fingers stimulated (2, 3, or 4 fingers; Experiment 1) or the number of stimulations on one fingertip (2, 3, or 4 stimulations; Experiment 2). Responses were faster and more accurate when the set of stimulated fingers corresponded to finger counting habits (Experiment 1) and when the number of stimulations matched the ordinal position of the stimulated finger (Experiment 2). These results show that tactile numerosity perception is affected by individual finger counting habits and that those habits give numerical meaning to single fingers.
Researchers examining the accuracy of observers ratings of others are devoting increased attention to peer-reported personality traits. Thus, the main purpose of this study was to investigate convergent validity of the three-factor Dark Triad model of personality framework, using two different rating methods: self-ratings and peer-ratings. Each participant (N = 266) was asked to collect three peer ratings (total peers N = 798). First, respondents completed three Dark Triad measures-Mach IV, SRP-III, and NPI-17 instruments. The peer-report forms of these instruments consisted of the same items as in the self-report version, but the rephrasing was appropriate to a third-person perspective. With the exception of one subscale of narcissism, Dark Triad measures demonstrated substantial convergent validity. These findings challenge views that at least two dark personality characteristics, i.e. psychopathy and Machiavellianism, are accurately observable phenomenon. The influences of agreement between self and other raters are discussed in relation to the degree of ratability and social desirability.
Sanktionen sind ein wichtiges Instrument des UN-Sicherheitsrats zur Erhaltung des Weltfriedens. Viele zentrale Entscheidungen, wie etwa die Listung und Entlistung terrorverdächtiger Personen, werden fernab der Öffentlichkeit in Sanktionsausschüssen getroffen. Die Einsetzung dieser Ausschüsse hat die Entscheidungsdynamiken im Rat erheblich verändert.
Energieversorgung
(2018)
German football stadiums are well known for their atmosphere. It is often described as 'electrifying,' or 'cracking.' This article focuses on this atmosphere. Using a phenomenological approach, it explores how this emotionality can be understood and how geography matters while attending a match. Atmosphere in this context is conceptualized based on work by as a mood-charged space, neither object- nor subject-centered, but rather a medium of perception which cannot not exist. Based on qualitative research done in the home stadium of Hertha BSC in the German Bundesliga, this article shows that the bodily sensations experienced by spectators during a visit to the stadium are synchronized with events on the pitch and with the more or less imposing scenery. The analysis ofin situdiaries reveals that spectators experience a comprehensive sense of collectivity. The study presents evidence that the occurrence of these bodily sensations is strongly connected with different aspects of spatiality. This includes sensations of constriction and expansion within the body, an awareness of one's location within the stadium, the influence of the immediate surroundings and cognitive here/there and inside/outside distinctions.
Web Tracking
(2018)
Web tracking seems to become ubiquitous in online business and leads to increased privacy concerns of users. This paper provides an overview over the current state of the art of web-tracking research, aiming to reveal the relevance and methodologies of this research area and creates a foundation for future work. In particular, this study addresses the following research questions: What methods are followed? What results have been achieved so far? What are potential future research areas? For these goals, a structured literature review based upon an established methodological framework is conducted. The identified articles are investigated with respect to the applied research methodologies and the aspects of web tracking they emphasize.
Track and Treat
(2018)
E-Mail tracking mechanisms gather information on individual recipients’ reading behavior. Previous studies show that e-mail newsletters commonly include tracking elements. However, prior work does not examine the degree to which e-mail senders actually employ gathered user information. The paper closes this research gap by means of an experimental study to clarify the use of tracking-based infor- mation. To that end, twelve mail accounts are created, each of which subscribes to a pre-defined set of newsletters from companies based in Germany, the UK, and the USA. Systematically varying e-mail reading patterns across accounts, each account simulates a different type of user with individual read- ing behavior. Assuming senders to track e-mail reading habits, we expect changes in mailer behavior. The analysis confirms the prominence of tracking in that over 92% of the newsletter e-mails contain tracking images. For 13 out of 44 senders an adjustment of communication policy in response to user reading behavior is observed. Observed effects include sending newsletters at different times, adapting advertised products to match the users’ IT environment, increased or decreased mailing frequency, and mobile-specific adjustments. Regarding legal issues, not all companies that adapt the mail-sending behavior state the usage of such mechanisms in their privacy policy.
Der Wandel zur automatisierten Produktion, die fortschreitende Digitalisierung der Wertschöpfungsprozesse sowie die stetige Implementierung von mobilen Industrial Internet of Things-Technologien (IIoT) in diese zur Unterstützung der Mitarbeiter stellen betriebliche Weiterbildung vor Herausforderungen. Komple-xere Anforderungen und veränderte Tätigkeitsprofile erfordern Handlungskom-petenzen bei Mitarbeitern im Sinne der Fähigkeit, in unbekannten Situationen auf Basis eigenen Könnens handlungsfähig zu bleiben. Jene sowie dafür notwendiges umfassendes Verständnis gegenüber digitalisierten Produktions-prozessen kann jedoch durch konventionelle Lehrmethoden nicht realisiert werden, da diese der erhöhten Anforderungskomplexität und den komplexen Rückkopplungen im Rahmen der Steuer- und Regelkreise nicht gerecht werden können. Diese Aspekte aufgreifend wird im Folgenden ein szenariobasierter Wei-terbildungsansatz für eine Lernfabrik vorgestellt, der insbesondere die Potenziale mobiler IIoT-Technologien zur Ausgestaltung dieser in den Blick nimmt.
Die (fast) vergessene Mauer
(2018)
Anfänge der Globalisierung
(2018)
Bildung zur Selbständigkeit
(2018)
Die Sorge um die Vorsorge
(2018)
Das "weiße Gold" in Preußen
(2018)
Social Entrepreneurship
(2018)
Nur mal kurz die Welt retten – und ganz nebenbei eine erfolgreiche Unternehmerin/ein erfolgreicher Unternehmer sein? Beispiele für das sogenannte Social Entrepreneurship findet man heutzutage viele. Hierunter versteht man die Bearbeitung gesellschaftlicher Probleme mit Hilfe des unternehmerischen Ansatzes. Unternehmerischer Gewinn steht hier jedoch nicht an erster Stelle, sondern der Beitrag zur Bewältigung gesellschaftlicher Herausforderungen. Aber auch in ganz „normalen“ Unternehmen spielen soziale, wie auch ökologische Faktoren heute eine wachsende Rolle.
Im vorliegenden Modul gewinnen die Schülerinnen und Schüler anhand des Films „Unternehmen wagen – 3 Wege in die Selbstständigkeit“ einen Einblick in die Unternehmerwelt. Sie lernen exemplarische Beispiele für (soziales) Unternehmertum kennen, analysieren diese vor dem Hintergrund des Konzepts Social Entrepreneurship und diskutieren verschiedene Facetten unternehmerischer Verantwortung.
Wer ein Unternehmen gründet, trägt ein hohes Maß an Verantwortung – nicht nur für die eigene Person, sondern für den gesamten Betrieb. Entscheidungen wollen bedächtig und rational kalkuliert sein und nicht aus dem Bauch heraus getroffen werden. Manche von ihnen wiegen schwer. Auch scheitern viele kreative Köpfe mit ihrer Gründungsidee, noch bevor sie ihr volles Potenzial entfalten kann.
The focus in this article, through a reading of the German-Australian newspaper Der Kosmopolit, is on the legacies of entangled imperial identities in the period of the nineteenth-century German Enlightenment. Attention is drawn to members of the liberal nationalist generation of 1848 who emigrated to the Australian colonies and became involved in intellectual activities there. The idea of entanglement is applied to the philosophical orientation of the German-language newspaper that this group formed, Der Kosmopolit, which was published between 1856 and 1957. Against simplistic notions that would view cosmopolitanism as the opposite of nationalism, it is argued that individuals like Gustav Droege and Carl Muecke deployed an entangled ‘cosmo-nationalism’ in ways that both advanced German nationalism and facilitated their own engagement with and investment in Australian colonial society.
Weil ich hier leben will ...
(2018)
Gibt es im 21. Jahrhundert so etwas wie ein „deutsches Judentum“? Wie sinnvoll ist das Reden von einer jüdischen Renaissance, wenn sich Jüdinnen und Juden heute ganz neu und in Abgrenzung zu alten Bildern und Vorstellungen definieren? Was bedeutet es für Deutschland, wenn sich Jüdinnen und Juden mit anderen religiösen, ethnischen und kulturellen Minderheiten solidarisieren und sich nicht gegen sie ausspielen lassen möchten? Und wie ist dem neu erwachenden Antisemitismus zu begegnen? Junge Jüdinnen und Juden in Deutschland schreiben an gegen altbewährte Klischees und Voreingenommenheiten. Und sie zeigen wie anders und lebendig jüdisches Leben heute ist.
Students often enter higher education academically unprepared and with unrealistic perceptions and expectations regarding academic competencies for their studies. However, preparedness and realistic perceptions are important factors for student retention. With regard to a proposed model of five academic competencies(time management, learning skills, technology proficiency, self-monitoring, and research skills), incoming students’ perceptions concerning academic staff support and students’ selfreported confidence at a German university were examined. Using quantitative data, an initial exploratory study was conducted (N = 155), which revealed first-year students’ perceptions of the role of academic staff in supporting their development, especially in
research skills, as well as low self-reported confidence in this competence. Thus, a follow up study (N = 717) was conducted to confirm these findings as well as to provide an indepth understanding of research skills. Understanding students’ perceptions is crucial if higher education institutions are to meet students’ needs and provide adequate support services in the challenging first year. Thus, in order to increase student retention, it is
suggested that universities assist first-year students in developing academic competencies through personalised competence-based programs and with the help of emerging
research fields and educational technologies such as learning analytics and digital badges.
Bilingual Disorder
(2018)
nempe exemplis discimus
(2018)
‘Tradition’ and ‘example’ are key concepts of the ancient fable. The fable has not only developed a literary tradition of its own, but from the beginning, it was also used as a rhetorical device, the exemplum. A diachronic overview of the genre and especially the use of the fable as exemplum reveals that Phaedrus adapts these terms in a new and ingenious way. In a case study of fable 3.9 this paper demonstrates how the fable finds its place in the literary tradition of the motif, how Socrates is presented as a model for the poet’s persona and how an intricate network of inter- and intratextual references is established between Socrates, Aesop, Phaedrus, and his potential successors. The subtle irony of the poet is particularly evident in the gradual development of the poet’s persona into a caricature, but the message of the fable itself remains unaffected: the value of true friendship.
Over the past few years, studying abroad and other educational international experiences have become increasingly highly regarded. Nevertheless, research shows that only a minority of students actually take part in
academic mobility programs. But what is it that distinguishes those students who take up these international opportunities from those who do not? In this
study we reviewed recent quantitative studies on why (primarily German) students choose to travel abroad or not. This revealed a pattern of predictive factors. These indicate the key role played by students’ personal and social background, as well as previous international travel and the course of studies they are enrolled in. The study then focuses on teaching students. Both facilitating and debilitating factors are discussed and included in a model illustrating the decision-making process these students use. Finally, we discuss the practical implications for ways in which international, studyrelated travel might be increased in the future. We suggest that higher education institutions analyze individual student characteristics, offering differentiated programs to better meet the needs of different groups, thus raising the likelihood of disadvantaged students participating in academic international travel.
In the course of patient treatments, psychotherapists aim to meet the challenges of being both a trusted, knowledgeable conversation partner and a diligent documentalist. We are developing the digital whiteboard system Tele-Board MED (TBM), which allows the therapist to take digital notes during the session together with the patient. This study investigates what therapists are experiencing when they document with TBM in patient sessions for the first time and whether this documentation saves them time when writing official clinical documents. As the core of this study, we conducted four anamnesis session dialogues with behavior psychotherapists and volunteers acting in the role of patients. Following a mixed-method approach, the data collection and analysis involved self-reported emotion samples, user experience curves and questionnaires. We found that even in the very first patient session with TBM, therapists come to feel comfortable, develop a positive feeling and can concentrate on the patient. Regarding administrative documentation tasks, we found with the TBM report generation feature the therapists save 60% of the time they normally spend on writing case reports to the health insurance.
Word recognition in sentence reading is influenced by information from both preview and context. Recently, semantic preview effect (SPE) was observed being modulated by the constraint of context, indicating that context might accelerate the processing of semantically related preview words. Besides, SPE was found to depend on preview time, which suggests that SPE may change with different processing stages of preview words. Therefore, it raises the question of whether preview time-dependent SPE would be modulated by contextual constraint. In this study, we not only investigated the impact of contextual constraint on SPE in Chinese reading but also examined its dependency on preview time. The preview word and the target word were identical, semantically related or unrelated to the target word. The results showed a significant three-way interaction: The SPE depended on contextual constraint and preview time. In separate analyses for low and high contextual constraint of target words, the SPE significantly decreased with an increase in preview duration when the target word was of low constraint in the sentence. The effect was numerically in the same direction but weaker and statistically nonsignificant when the target word was highly constrained in the sentence. The results indicate that word processing in sentences is a dynamic process of integrating information from both preview (bottom-up) and context (top-down).
Morphological structure influences the initial landing position in words during reading Finnish
(2018)
The preferred viewing location in words [Rayner, K. (1979). Eye guidance in reading: Fixation locations within words. Perception, 8, 21–30] during reading is near the word centre. Parafoveal word length information is utilized to guide the eyes toward it. A recent study by Yan and colleagues [Yan, M., Zhou, W., Shu, H., Yusupu, R., Miao, D., Krügel, A., & Kliegl, R. (2014). Eye movements guided by morphological structure: Evidence from the Uighur language. Cognition, 132, 181–215] demonstrated that the word’s morphological structure may also be used in saccadic targeting. The study was conducted in a morphologically rich language, Uighur. The present study aimed at replicating their main findings in another morphologically rich language, Finnish. Similarly to Yan et al., it was found that the initial fixation landed closer to the word beginning for morphologically complex than for monomorphemic words. Word frequency, saccade launch site, and word length were also found to influence the initial landing position. It is concluded that in addition to low-level factors (word length and saccade launch site), also higher level factors related to the word’s morphological structure and frequency may be utilized in saccade programming during reading.
The visual number world
(2018)
In the domain of language research, the simultaneous presentation of a visual scene and its auditory description (i.e., the visual world paradigm) has been used to reveal the timing of mental mechanisms. Here we apply this rationale to the domain of numerical cognition in order to explore the differences between fast and slow arithmetic performance, and to further study the role of spatial-numerical associations during mental arithmetic. We presented 30 healthy adults simultaneously with visual displays containing four numbers and with auditory addition and subtraction problems. Analysis of eye movements revealed that participants look spontaneously at the numbers they currently process (operands, solution). Faster performance was characterized by shorter latencies prior to fixating the relevant numbers and fewer revisits to the first operand while computing the solution. These signatures of superior task performance were more pronounced for addition and visual numbers arranged in ascending order, and for subtraction and numbers arranged in descending order (compared to the opposite pairings). Our results show that the visual number world-paradigm provides on-line access to the mind during mental arithmetic, is able to capture variability in arithmetic performance, and is sensitive to visual layout manipulations that are otherwise not reflected in response time measurements.
Second harmonic generation (SHG) is a nonlinear optical process that inherently generates signal in non-centrosymmetric materials, such as starch granules, and therefore can be used for label-free imaging. Both intensity and polarization of SHG are determined by material properties that are characterized by the nonlinear susceptibility tensor, ((2)). Examination of the tensor is performed for each focal volume of the image by measuring the outgoing polarization state of the SHG signal for a set of incoming laser beam polarizations. Mapping of nonlinear properties expressed as the susceptibility ratio reveals structural features including the organization of crystalline material within a single starch granule, and the distribution of structural properties in a population of granules. Isolated granules, as well as in situ starch, can be analyzed using polarimetric SHG microscopy. Due to the fast sample preparation and short imaging times, polarimetric SHG microscopy allows for a quick assessment of starch structure and permits rapid feedback for bioengineering applications. This article presents the basics of SHG theory and microscopy applications for starch-containing materials. Quantification of ultrastructural features within individual starch granules is described. New results obtained by polarization resolved SHG microscopy of starch granules are presented for various maize genotypes revealing heterogeneity within a single starch particle and between various granules.
BackgroundClinical swallowing assessment is largely limited to qualitative assessment of behavioural observations. There are limited quantitative data that can be compared with a healthy population for identification of impairment. The Test of Masticating and Swallowing Solids (TOMASS) was developed as a quantitative assessment of solid bolus ingestion. AimsThis research programme investigated test development indices and established normative data for the TOMASS to support translation to clinical dysphagia assessment. Conclusions & ImplicationsThe TOMASS is presented as a valid, reliable and broadly normed clinical assessment of solid bolus ingestion. Clinical application may help identify dysphagic patients at bedside and provide a non-invasive, but sensitive, measure of functional change in swallowing.
Ziel ist die Überprüfung der kurz- und mittelfristigen Wirksamkeit einer vorschulischen Förderung des Mengen- und Zahlenverständnisses bei Kindern mit einem Risiko für die Entwicklung einer Rechenstörung. Es wurden 32 Risikokinder mit einer Kombination aus den Förderprogrammen Mathematik im Vorschulalter und Mengen, zählen, Zahlen im letzten Kindergartenjahr von den Erzieherinnen trainiert und mit 38 untrainierten Risikokindern verglichen. Hinsichtlich der kurzfristigen Wirksamkeit zeigten sich positive Trainingseffekte auf die numerischen Leistungen im letzten Kindergartenjahr. Es ließen sich keine signifikanten mittelfristigen Trainingseffekte auf die Rechenleistungen im zweiten Halbjahr der 1. Klasse finden. Das eingesetzte vorschulische Präventionsprogramm leistete danach einen wichtigen Beitrag zur kurzfristigen Verbesserung der mathematischen Basiskompetenzen.
Rommel Almighty?
(2018)
Erwin Rommel is by any standard a mythical figure. He has been the subject of countless studies in English and German. However, the "Italian side of the hill" has been largely neglected, despite the fact that the foundation of the myth around him lies in the North African campaign, where, after all, thousands of soldiers of the Italian army fought alongside the african campaign, where, after all, thousands of soldiers of the Italian army fought along-side the Afrika Korps. This article will provide an Italian view of the "Desert Fox," using new primary material that provides insights into Italian assessments during the war. A major source is material gathered by way of eavesdropping by British intelligence on Italian officers held as POWs in Cairo and in England.
Immunochemical analytical methods are very successful in clinical diagnostics and are nowadays also emerging in the control of food as well as monitoring of environmental issues. Among the different immunoassays, luminescence based formats are characterized by their outstanding sensitivity making this format especially attractive for future applications. The need for multiparameter detection capabilities calls for a tool box of dye labels in order to transduce the biochemical reaction into an optically detectable signal. Here, in a multiparameter approach each analyte may be detected by a different dye with a unique emission color (covering the blue to red spectral range) or a unique luminescence decay kinetics. In the case of a competitive immunoassay format for each of the different dye labels an individual antibody would be needed. In the present paper a slightly modified approach is presented using a 7-aminocoumarin unit as the basic antigen against which highly specific antibodies were generated. Leaving the epitope region in the dyes unchanged but introducing a side group in positon 3 of the coumarin system allowed us to tune the optical properties of the coumarin dyes without the necessity of new antibody generation. Upon modification of the parent coumarin unit the full spectral range from blue to deep red was accessed. In the manuscript the photophysical characterization of the coumarin derivatives and their corresponding immunocomplexes with two highly specific antibodies is presented. The coumarin dyes and their immunocomplexes were characterized by steady-state and time-resolved absorption as well as emission spectroscopy. Moreover, fluorescence depolarization measurements were carried out to complement the data stressing the different binding modes of the two antibodies. The binding modes were evaluated using the photophysics of 7-aminocoumarins and how it was affected in the respective immunocomplexes, namely, the formation of the intramolecular charge transfer (ICT) as well as the twisted intramolecular charge transfer (TICT). In contrast to other antibody-dye pairs reported a distinct fluorescence enhancement upon formation of the antibody-dye complex up to a factor of SO was found. Because of the easy emission color tuning by tailoring the coumarin substitution for the antigen binding in nonrelevant position 3 of the parent molecule, a dye tool box is on hand which can be used in the construction of competitive multiparameter fluorescence enhancement immunoassays (FenIA).
Feeling Half-Half?
(2018)
Growing up in multicultural environments, Turkish-heritage individuals in Europe face specific challenges in combining their multiple cultural identities to form a coherent sense of self. Drawing from social identity complexity, this study explores four modes of combining cultural identities and their variation in relational contexts. Problem-centered interviews with Turkish-heritage young adults in Austria revealed the preference for complex, supranational labels, such as multicultural. Furthermore, most participants described varying modes of combining cultural identities over time and across relational contexts. Social exclusion experiences throughout adolescence related to perceived conflict of cultural identities, whereas multicultural peer groups supported perceived compatibility of cultural identities. Findings emphasize the need for complex, multidimensional approaches to study ethnic minorities’ combination of cultural identities.
We present a computational evaluation of three hypotheses about sources of deficit in sentence comprehension in aphasia: slowed processing, intermittent deficiency, and resource reduction. The ACT-R based Lewis and Vasishth (2005) model is used to implement these three proposals. Slowed processing is implemented as slowed execution time of parse steps; intermittent deficiency as increased random noise in activation of elements in memory; and resource reduction as reduced spreading activation. As data, we considered subject vs. object relative sentences, presented in a self-paced listening modality to 56 individuals with aphasia (IWA) and 46 matched controls. The participants heard the sentences and carried out a picture verification task to decide on an interpretation of the sentence. These response accuracies are used to identify the best parameters (for each participant) that correspond to the three hypotheses mentioned above. We show that controls have more tightly clustered (less variable) parameter values than IWA; specifically, compared to controls, among IWA there are more individuals with slow parsing times, high noise, and low spreading activation. We find that (a) individual IWA show differential amounts of deficit along the three dimensions of slowed processing, intermittent deficiency, and resource reduction, (b) overall, there is evidence for all three sources of deficit playing a role, and (c) IWA have a more variable range of parameter values than controls. An important implication is that it may be meaningless to talk about sources of deficit with respect to an abstract verage IWA; the focus should be on the individual's differential degrees of deficit along different dimensions, and on understanding the causes of variability in deficit between participants.
WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity
(2018)
Auxin is unique among plant hormones due to its directional transport that is mediated by the polarly distributed PIN auxin transporters at the plasma membrane. The canalization hypothesis proposes that the auxin feedback on its polar flow is a crucial, plant-specific mechanism mediating multiple self-organizing developmental processes. Here, we used the auxin effect on the PIN polar localization in Arabidopsis thaliana roots as a proxy for the auxin feedback on the PIN polarity during canalization. We performed microarray experiments to find regulators of this process that act downstream of auxin. We identified genes that were transcriptionally regulated by auxin in an AXR3/IAA17-and ARF7/ARF19-dependent manner. Besides the known components of the PIN polarity, such as PID and PIP5K kinases, a number of potential new regulators were detected, among which the WRKY23 transcription factor, which was characterized in more detail. Gain-and loss-of-function mutants confirmed a role for WRKY23 in mediating the auxin effect on the PIN polarity. Accordingly, processes requiring auxin-mediated PIN polarity rearrangements, such as vascular tissue development during leaf venation, showed a higher WRKY23 expression and required the WRKY23 activity. Our results provide initial insights into the auxin transcriptional network acting upstream of PIN polarization and, potentially, canalization-mediated plant development.
Biodiversity has suffered a dramatic global decline during the past decades, and monitoring tools are urgently needed providing data for the development and evaluation of conservation efforts both on a species and on a genetic level. However, in wild species, the assessment of genetic diversity is often hampered by the lack of suitable genetic markers. In this article, we present Random Amplicon Sequencing (RAMseq), a novel approach for fast and cost-effective detection of single nucleotide polymorphisms (SNPs) in nonmodel species by semideep sequencing of random amplicons. By applying RAMseq to the Eurasian otter (Lutra lutra), we identified 238 putative SNPs after quality filtering of all candidate loci and were able to validate 32 of 77 loci tested. In a second step, we evaluated the genotyping performance of these SNP loci in noninvasive samples, one of the most challenging genotyping applications, by comparing it with genotyping results of the same faecal samples at microsatellite markers. We compared (i) polymerase chain reaction (PCR) success rate, (ii) genotyping errors and (iii) Mendelian inheritance (population parameters). SNPs produced a significantly higher PCR success rate (75.5% vs. 65.1%) and lower mean allelic error rate (8.8% vs. 13.3%) than microsatellites, but showed a higher allelic dropout rate (29.7% vs. 19.8%). Genotyping results showed no deviations from Mendelian inheritance in any of the SNP loci. Hence, RAMseq appears to be a valuable tool for the detection of genetic markers in nonmodel species, which is a common challenge in conservation genetic studies.
This article describes architectural extensions for a dynamically scheduled processor to enable three different operation modes, ranging from high-performance, to high-reliability. With minor extensions of the control path, the resources of the super-scalar data-path can be used either for high-performance execution, fail-safe-operation, or fault-tolerant-operation. Furthermore, the online error-correction capabilities are combined with reconfiguration techniques for permanent fault handling. This reconfiguration can take defective components out of operation permanently, and can be triggered on-demand during runtime, depending on the frequency of online corrected faults. A comprehensive fault simulation was carried out in order to evaluate hardware overhead, fault coverage and performance penalties of the proposed approach. Moreover, the impact of the permanent reconfiguration regarding the reliability and performance is investigated.
Social participation of pupils with special educational needs (SEN) is a central topic in the current inclusion debate. Numerous studies have shown that the risk of social exclusion is considerably higher for children with SEN compared to their peers without SEN, especially for pupils with behaviour problems (BP) or learning difficulties (LD). Since most of these studies are based on cross-sectional designs, there is a lack of knowledge regarding the direction of the effects. This leads to the question to what extent BP and LD have an impact on pupils’ social position in the class and, vice versa, to what extent the social position has an effect on the development of BP and LD. To address these questions, we analysed sociometric data of 1244 primary school children. È A cross-lagged panel analysis was conducted. The results indicate that BP and LD in 1st grade lead to significantly less social acceptance by peers in 2nd grade but do not predict significantly higher social rejection. A directed influence of LD or BP on a higher social rejection cannot be found. Conversely, neither social acceptance nor social rejection at 1st grade has an influence on the development of BP or LD at grade two.
Like almost all fields of science, hydrology has benefited to a large extent from the tremendous improvements in scientific instruments that are able to collect long-time data series and an increase in available computational power and storage capabilities over the last decades. Many model applications and statistical analyses (e.g., extreme value analysis) are based on these time series. Consequently, the quality and the completeness of these time series are essential. Preprocessing of raw data sets by filling data gaps is thus a necessary procedure. Several interpolation techniques with different complexity are available ranging from rather simple to extremely challenging approaches. In this paper, various imputation methods available to the hydrological researchers are reviewed with regard to their suitability for filling gaps in the context of solving hydrological questions. The methodological approaches include arithmetic mean imputation, principal component analysis, regression-based methods and multiple imputation methods. In particular, autoregressive conditional heteroscedasticity (ARCH) models which originate from finance and econometrics will be discussed regarding their applicability to data series characterized by non-constant volatility and heteroscedasticity in hydrological contexts. The review shows that methodological advances driven by other fields of research bear relevance for a more intensive use of these methods in hydrology. Up to now, the hydrological community has paid little attention to the imputation ability of time series models in general and ARCH models in particular.
Coordinated cell polarization in developing tissues is a recurrent theme in multicellular organisms. In plants, a directional distribution of the plant hormone auxin is at the core of many developmental programs. A feedback regulation of auxin on the polarized localization of PIN auxin transporters in individual cells has been proposed as a self-organizing mechanism for coordinated tissue polarization, but the molecular mechanisms linking auxin signalling to PIN-dependent auxin transport remain unknown. We used a microarray-based approach to find regulators of the auxin-induced PIN relocation in Arabidopsis thaliana root, and identified a subset of a family of phosphatidylinositol transfer proteins (PITPs), the PATELLINs (PATLs). Here, we show that PATLs are expressed in partially overlapping cell types in different tissues going through mitosis or initiating differentiation programs. PATLs are plasma membrane-associated proteins accumulated in Arabidopsis embryos, primary roots, lateral root primordia and developing stomata. Higher order patl mutants display reduced PIN1 repolarization in response to auxin, shorter root apical meristem, and drastic defects in embryo and seedling development. This suggests that PATLs play a redundant and crucial role in polarity and patterning in Arabidopsis.
In angiosperms, the gynoecium is the last structure to develop within the flower due to the determinate fate of floral meristem (FM) stem cells. The maintenance of stem cell activity before its arrest at the stage called FM termination affects the number of carpels that develop. The necessary inhibition at this stage of WUSCHEL (WUS), which is responsible for stem cell maintenance, involves a two-step mechanism. Direct repression mediated by the MADS domain transcription factor AGAMOUS (AG), followed by indirect repression requiring the C2H2 zinc-finger protein KNUCKLES (KNU), allow for the complete termination of floral stem cell activity. Here, we show that Arabidopsis thaliana MINI ZINC FINGER2 (AtMIF2) and its homolog in tomato (Solanum lycopersicum), INHIBITOR OF MERISTEM ACTIVITY (SlIMA), participate in the FM termination process by functioning as adaptor proteins. AtMIF2 and SlIMA recruit AtKNU and SlKNU, respectively, to form a transcriptional repressor complex together with TOPLESS and HISTONE DEACETYLASE19. AtMIF2 and SlIMA bind to the WUS and SIWUS loci in the respective plants, leading to their repression. These results provide important insights into the molecular mechanisms governing (FM) termination and highlight the essential role of AtMIF2/SlIMA during this developmental step, which determines carpel number and therefore fruit size.
The globally distributed sperm whale (Physeter macrocephalus) has a partly matrilineal social structure with predominant male dispersal. At the beginning of 2016, a total of 30 male sperm whales stranded in five different countries bordering the southern North Sea. It has been postulated that these individuals were on a migration route from the north to warmer temperate and tropical waters where females live in social groups. By including samples from four countries (n = 27), this event provided a unique chance to genetically investigate the maternal relatedness and the putative origin of these temporally and spatially co-occuring male sperm whales. To utilize existing genetic resources, we sequenced 422 bp of the mitochondrial control region, a molecular marker for which sperm whale data are readily available from the entire distribution range. Based on four single nucleotide polymorphisms (SNPs) within the mitochondrial control region, five matrilines could be distinguished within the stranded specimens, four of which matched published haplotypes previously described in the Atlantic. Among these male sperm whales, multiple matrilineal lineages co-occur. We analyzed the population differentiation and could show that the genetic diversity of these male sperm whales is comparable to the genetic diversity in sperm whales from the entire Atlantic Ocean. We confirm that within this stranding event, males do not comprise maternally related individuals and apparently include assemblages of individuals from different geographic regions. (c) 2017 Deutsche Gesellschaft fur Saugetierkunde. Published by Elsevier GmbH. All rights reserved.
Studies on Oberonia 3. Aberrant flowers and other floral modifications in the orchid genus Oberonia
(2018)
Orchid flowers are amongst the most conspicuous attractions that plants have generated over evolutionary epochs. However, organ homology in particular of androecium and gynoecium of orchid flowers have been, and are still, the subject of long-term discussion. Studies of aberrant - teratologic - flowers have traditionally helped to clarify organ identity in orchids. We here present for the first time teratological flowers within the florally smallest and inconspicuous orchid genus Oberonia and illustrate them by light and scanning electron microscopy. Pseudopeloria with half of a lateral petal transformed into a lip was found in O. costeriana J.J.Sm. and O. mucronata (D.Don) Ormerod & Seidenf. A supernumerary lip is known from O. mucronata. Oberonia rufilabris Lindl. is documented with multiple aberrations: triple gynostemium and a total of 10 tepals, twin flowers, and duplicate lips. We interpret these aberrations in light of known floral developmental and organ identity information.