Refine
Year of publication
- 2012 (1321) (remove)
Document Type
- Article (960)
- Doctoral Thesis (158)
- Conference Proceeding (52)
- Preprint (43)
- Postprint (39)
- Review (31)
- Monograph/Edited Volume (22)
- Other (9)
- Part of a Book (2)
- Master's Thesis (2)
- Working Paper (2)
- Habilitation Thesis (1)
Language
- English (1321) (remove)
Keywords
- Curriculum Framework (16)
- European values education (16)
- Europäische Werteerziehung (16)
- Lehrevaluation (16)
- Studierendenaustausch (16)
- Unterrichtseinheiten (16)
- curriculum framework (16)
- lesson evaluation (16)
- student exchange (16)
- teaching units (16)
Institute
- Institut für Biochemie und Biologie (235)
- Institut für Physik und Astronomie (215)
- Institut für Chemie (174)
- Institut für Geowissenschaften (170)
- Department Psychologie (75)
- Institut für Mathematik (60)
- Institut für Ernährungswissenschaft (55)
- Institut für Informatik und Computational Science (41)
- Department Linguistik (29)
- Department Sport- und Gesundheitswissenschaften (29)
This article addresses the problem of estimating the Quality of Service (QoS) of a composite service given the QoS of the services participating in the composition. Previous solutions to this problem impose restrictions on the topology of the orchestration models, limiting their applicability to well-structured orchestration models for example. This article lifts these restrictions by proposing a method for aggregate QoS computation that deals with more general types of unstructured orchestration models. The applicability and scalability of the proposed method are validated using a collection of models from industrial practice.
Queerly intimate friends, fans and affective communication in a Super Girl fan fiction community
(2012)
This article examines the rise of the Girls' Love (GL) fan fiction community in contemporary China. More specifically, we focus on the 'Pink Super Girl Bar', an online fan fiction community devoted to the pairing of the contestants of the 2006 season of Super Girl, an entertainment program featured on Hunan Satellite TV that enjoys great popularity in the Sinophone world. Through an ethnographic account of the formation, convention and performativity of identities and socialities in this community, we demonstrate how Super Girl GL fans mobilize their emotional capital to create artworks, to have fun and to enrich their everyday lives. We argue that the GL fan fiction community has become a space of female homosociality, intimacy and affect in which a new generation of young Chinese women actively enact friendship and female subjectivity in a way that refuses the normalization of gender, sexuality and social relations. Moreover, by linking fan studies to affect studies and emotional geography, and by paying particular attention to indigenous concepts and cultural practices in mainland China's fan communities, we wish to contribute to fan studies with feminist, queer and transnational perspectives.
Many studies have suggested that emotional stimuli orient and engage attention. There is also evidence that animate stimuli, such as those from humans and animals, cause attentional bias. However, categorical and emotional factors are usually mixed, and it is unclear to what extent human context influences attentional allocation. To address this issue, we tracked participants' eye movements while they viewed pictures with animals and inanimate images (i.e., category) as focal objects. These pictures had either negative or neutral emotional valence, and either human body parts or nonhuman parts were near the focal objects (i.e., context). The picture's valence, arousal, position, size, and most of the low-level visual features were matched across categories. The results showed that nonhuman animals were more likely to be attended to and to be attended to for longer times than inanimate objects. The same pattern held for the human contexts (vs. nonhuman contexts). The effects of emotional valence, category, and context interacted. Specifically, in images with a negative valence, focal animals and objects with human context had comparable numbers of gaze fixations and gaze duration. These results highlighted the attentional bias to animate parts of a picture and clarified that the effects of category, valence, and picture context interacted to influence attentional allocation.
Semantic processing from parafoveal words is an elusive phenomenon in alphabetic languages, but it has been demonstrated only for a restricted set of noncompound Chinese characters. Using the gaze-contingent boundary paradigm, this experiment examined whether parafoveal lexical and sublexical semantic information was extracted from compound preview characters. Results generalized parafoveal semantic processing to this representative set of Chinese characters and extended the parafoveal processing to radical (sublexical) level semantic information extraction. Implications for notions of parafoveal information extraction during Chinese reading are discussed.
Preview fixation duration modulates identical and semantic preview benefit in Chinese reading
(2012)
Semantic preview benefit from parafoveal words is critical for proposals of distributed lexical processing during reading. Semantic preview benefit has been demonstrated for Chinese reading with the boundary paradigm in which unrelated or semantically related previews of a target word N + 1 are replaced by the target word once the eyes cross an invisible boundary located after word N (Yan et al., 2009); for the target word in position N + 2, only identical compared to unrelated-word preview led to shorter fixation times on the target word (Yan et al., in press). A reanalysis of these data reveals that identical and semantic preview benefits depend on preview duration (i.e., the fixation duration on the preboundary word). Identical preview benefit from word N + 1 increased with preview duration. The identical preview benefit was also significant for N + 2, but did not significantly interact with preview duration. The previously reported semantic preview benefit from word N + 1 was mainly due to single- or first-fixation durations following short previews. We discuss implications for notions of serial attention shifts and parallel distributed processing of words during reading.
Transparent, ion-conducting, luminescent, and flexible ionogels based on the room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis(trifluoromethane sulfonyl) imide [Bmim][N(Tf)(2)], a PtEu2 chromophore, and poly(methylmethacrylate) (PMMA) have been prepared. The thermal stability of the PMMA significantly increases with IL incorporation. In particular, the onset weight loss observed at ca. 229 degrees C for pure PMMA increases to 305 degrees C with IL addition. The ionogel has a high ionic conductivity of 10(-3) S cm(-1) at 373 K and exhibits a strong emission in the red with a long average luminescence decay time of tau = 890 mu s. The resulting material is a new type of soft hybrid material featuring useful thermal, optical, and ion transport properties.
Friedreich ataxia (FRDA) is an inherited neurodegenerative disease caused by frataxin (FXN) deficiency. The nervous system and heart are the most severely affected tissues. However, highly mitochondria-dependent tissues, such as kidney and liver, are not obviously affected, although the abundance of FXN is normally high in these tissues. In this study we have revealed two novel FXN isoforms (II and III), which are specifically expressed in affected cerebellum and heart tissues, respectively, and are functional in vitro and in vivo. Increasing the abundance of the heart-specific isoform III significantly increased the mitochondrial aconitase activity, while over-expression of the cerebellum-specific isoform II protected against oxidative damage of Fe-S cluster-containing aconitase. Further, we observed that the protein level of isoform III decreased in FRDA patient heart, while the mRNA level of isoform II decreased more in FRDA patient cerebellum compared to total FXN mRNA. Our novel findings are highly relevant to understanding the mechanism of tissue-specific pathology in FRDA.
Hydrogel systems based on hydroxyethyl starch-polyethylene glycol methacrylate (HES-P(EG)(6)MA) or hydroxyethyl starch methacrylate (HES-MA) were used to assess the protein release behavior. Here, we analyzed the in vitro release of FITC-anti-human antibodies incorporated in either HES-P(EG)(6)MA or HES-MA hydrogel delivery systems in PBS or human serum. In addition, hydrogel disks and microparticles prepared from the two polymers were subcutaneously implanted in BALB/c mice. The in vivo release of FITC-IgG was non-invasively monitored by an in vivo imaging system (IVIS 200) over a time period of up to 3 months. The imaging system allowed to asses individual animals over time, therefore only a small number of animals was required to obtain high quality data. The reduction in fluorescence intensity at the site of administration was compared to in vitro release profiles. These investigations demonstrated a sustained release from HES-MA hydrogel disks compared to rapidly degrading HES-P(EG)(6)MA disks and microparticles. The sustained release from HES-MA disks could be further optimized by using increased polymer concentrations. Human serum as in vitro release medium reflected better the in vivo release from HES-P(EG)(6)MA systems than PBS, suggesting that the presence of organic substances like proteins or lipids may play a significant role for the release kinetics.
This article considers one of the major weaknesses in the existing historiography of Irish Jewry, the failure to consider the true extent and impact of antisemitism on Ireland’s Jewish community. This is illustrated through a brief survey of one small area of the Irish-Jewish narrative, the Jewish relationship with Irish nationalist politics. Throughout, the focus remains on the need for a fresh approach to the sources and the issues at hand, in order to create a more holistic, objective and inclusive history of the Jewish experience in Ireland.
Environmental actinorhodopsin expression revealed by a new in situ filtration and fixation sampler
(2012)
Freshwater Actinobacteria are an important and dominant group of bacterioplankton in most temperate freshwater systems. Recently, metagenomic studies discovered rhodopsin-like protein-coding sequences present in Actinobacteria which could be a decisive hint for their success in freshwater ecosystems. We analysed the diversity of actinorhodopsin (ActR) in Lake Stechlin (northern Germany) and assessed the actR expression profile during a diurnal cycle. We obtained 85 positive actR clones which could be subsequently grouped to 17 operational taxonomic units assuming a 90% sequence similarity. The phylogenetic analysis points to a close relationship of all obtained sequences to the acI lineage of Actinobacteria, forming six independent clusters. For the first time, we followed in situ transcription of actR in Lake Stechlin revealing a rather constitutive circadian gene expression. For analysing in situ expression patterns of functional genes in aquatic ecosystems, such as actR, we invented a new in situ filtration and fixation sampler (IFFS). The IFFS enables the representative investigation of microbial transcriptomes in any aquatic ecosystem at all water depths. The IFFS sampler is simple and inexpensive, and we provide all engineering plans for an easy rebuild. Consequently, our IFFS is suitable to reliably study expression of any known functional gene of any aquatic microorganism.
The sediment flux through Himalayan rivers directly impacts water quality and is important for sustaining agriculture as well as maintaining drinking-water and hydropower generation. Despite the recent increase in demand for these resources, little is known about the triggers and sources of extreme sediment flux events, which lower water quality and account for extensive hydropower reservoir filling and turbine abrasion. Here, we present a comprehensive analysis of the spatiotemporal trends in suspended sediment flux based on daily data during the past decade (2001-2009) from four sites along the Sutlej River and from four of its main tributaries. In conjunction with satellite data depicting rainfall and snow cover, air temperature and earthquake records, and field observations, we infer climatic and geologic controls of peak suspended sediment concentration (SSC) events. Our study identifies three key findings: First, peak SSC events (a parts per thousand yen 99th SSC percentile) coincide frequently (57-80%) with heavy rainstorms and account for about 30% of the suspended sediment flux in the semi-arid to arid interior of the orogen. Second, we observe an increase of suspended sediment flux from the Tibetan Plateau to the Himalayan Front at mean annual timescales. This sediment-flux gradient suggests that averaged, modern erosion in the western Himalaya is most pronounced at frontal regions, which are characterized by high monsoonal rainfall and thick soil cover. Third, in seven of eight catchments, we find an anticlockwise hysteresis loop of annual sediment flux variations with respect to river discharge, which appears to be related to enhanced glacial sediment evacuation during late summer. Our analysis emphasizes the importance of unconsolidated sediments in the high-elevation sector that can easily be mobilized by hydrometeorological events and higher glacial-meltwater contributions. In future climate change scenarios, including continuous glacial retreat and more frequent monsoonal rainstorms across the Himalaya, we expect an increase in peak SSC events, which will decrease the water quality and impact hydropower generation.
The transition from juvenility through maturation to senescence is a complex process that involves the regulation of longevity. Here, we identify JUNGBRUNNEN1 (JUB1), a hydrogen peroxide (H2O2)-induced NAC transcription factor, as a central longevity regulator in Arabidopsis thaliana. JUB1 overexpression strongly delays senescence, dampens intracellular H2O2 levels, and enhances tolerance to various abiotic stresses, whereas in jub1-1 knockdown plants, precocious senescence and lowered abiotic stress tolerance are observed. A JUB1 binding site containing a RRYGCCGT core sequence is present in the promoter of DREB2A, which plays an important role in abiotic stress responses. JUB1 transactivates DREB2A expression in mesophyll cell protoplasts and transgenic plants and binds directly to the DREB2A promoter. Transcriptome profiling of JUB1 overexpressors revealed elevated expression of several reactive oxygen species-responsive genes, including heat shock protein and glutathione S-transferase genes, whose expression is further induced by H2O2 treatment. Metabolite profiling identified elevated Pro and trehalose levels in JUB1 overexpressors, in accordance with their enhanced abiotic stress tolerance. We suggest that JUB1 constitutes a central regulator of a finely tuned control system that modulates cellular H2O2 level and primes the plants for upcoming stress through a gene regulatory network that involves DREB2A.
The recent decades have witnessed the incorporation of new linguistic trends into lexicography. One of these trends is a usage-based approach, with the first major application of computer-corpus data in the Collins COBUILD English dictionary (1995) and successive adaptation in other L1-dictionaries. Another, concurrent innovation-inspired by Conceptual Metaphor Theory-is the provision of conceptual information in monolingual dictionaries of English. So far, however, only the Macmillan English dictionary for advanced learners (1st and 2nd edition) has paid tribute to the fact that understanding culturespecific metaphors and being aware of metaphoric usage are crucial for learning a foreign language. Given that most of the English as lingua franca interactions take place between L2-speakers of English (see Kachru, 1994), providing conceptual information is not only a desideratum for L1- and learner dictionaries, but especially for (L2-) variety dictionaries of English. In our paper, we follow earlier tentative proposals by Polzenhagen (2007) and Wolf (2012) and present examples from A dictionary of Hong Kong English (Cummings & Wolf, 2011), showing how culturally salient conceptual information can be made explicit and conceptual links between lexical items retrievable. The examples demonstrate that fixed expressions and idioms -a perennial problem for lexicographers are explicable by means of the proposed lexicographic design, too. Our approach is cognitive-sociolinguistic in that the Conceptual Metaphor approach is coupled with the study of regional varieties of English, more specifically Hong Kong English. Our analysis is empirically backed up by corpus-linguistic insights into this L2 variety.