Filtern
Volltext vorhanden
- nein (1272) (entfernen)
Erscheinungsjahr
- 2006 (1272) (entfernen)
Dokumenttyp
- Wissenschaftlicher Artikel (904)
- Monographie/Sammelband (159)
- Dissertation (126)
- Rezension (53)
- Sonstiges (25)
- Teil eines Buches (Kapitel) (1)
- Konferenzveröffentlichung (1)
- Lehrmaterial (1)
- Bewegte Bilder (1)
- Zeitschrift/Schriftenreihe (1)
Sprache
- Englisch (663)
- Deutsch (585)
- Französisch (11)
- Spanisch (8)
- Italienisch (3)
- Polnisch (2)
Gehört zur Bibliographie
- ja (1272)
Schlagworte
- Dead Sea Transform (2)
- Poetik (2)
- cave fish (2)
- competition (2)
- metabolomics (2)
- microemulsion (2)
- polyelectrolyte (2)
- protein (2)
- protein translocation (2)
- singlet oxygen (2)
- (glycogen) starch phosphorylase (1)
- 1,3,4-oxadiazole (1)
- 16. Jahrhundert (1)
- Abgaben (1)
- Abgabenbescheide (1)
- Andreas Gryphius (1)
- Annelida (1)
- Anti-HIV (1)
- Arabidopsis thaliana (1)
- Argumentationstheorie (1)
- Aristoteles-Kommentare (1)
- Beiträge (1)
- CDA (1)
- Cassini (1)
- Celtic mutations (1)
- Chlamydomonas (1)
- DMSO (1)
- DSA (1)
- Deimos (1)
- Deutsche Literatur der Frühen Neuzeit (1)
- Drama (1)
- E-ring (1)
- EEG (1)
- EPR (1)
- Enthusiasmus (1)
- Frühe Neuzeit (1)
- GWD (1)
- Gebühren (1)
- Geld (1)
- Gleichnis (1)
- Größen (1)
- HOMA (1)
- India (1)
- Inspiration (1)
- Integrated Ocean Drilling Program (1)
- International Continental Scientific Drilling Program (1)
- Jacopo Zabarella (1)
- Jahn-Teller distortion (1)
- KAG (1)
- LBA problem (1)
- Lentibulariaceae (1)
- Lernvoraussetzungen (1)
- Li-F granite (1)
- Lindenmayer systems (1)
- MOCS2 (1)
- MSDA (1)
- Maldanidae (1)
- Mars (1)
- NF-X1 (1)
- Neuplatonismus (1)
- ORMOCER (R) (1)
- P-31 NMR (1)
- PWD (1)
- Pade approximants (1)
- Poecilia mexicana (1)
- Poeciliidae (1)
- Polychaeta (1)
- Quaternary (1)
- Ryukyu Group (1)
- Ryukyu Islands (1)
- S receiver functions (1)
- SAXS (1)
- SOD (1)
- SRP (1)
- Sambagawa (1)
- Schülerkompetenzen (1)
- Sesia Zone (1)
- Solanaceae (1)
- Solanum lycopersicum (1)
- Spitzbergen (1)
- Stenella attenuata (1)
- Steuern (1)
- Stormer-Verlet method (1)
- Th-U-Pb monazite age (1)
- Trypanosoma cruzi (1)
- Uganda (1)
- Utricularia (1)
- Western Ghats (1)
- X-ray mapping (1)
- X-rays : stars (1)
- Xiphophorus (1)
- Zaremba problem (1)
- accepting grammars (1)
- accessory minerals (1)
- accounting (1)
- activity patterns (1)
- acupuncture (1)
- adiponectin (1)
- adulthood (1)
- aflatoxin B-1 (1)
- agent-based model (1)
- aggregation (1)
- amino acid score (1)
- amylase activity (1)
- amylopectin (1)
- anatomical connectivity (1)
- anhydrite inclusions (1)
- anthracenes (1)
- antioxidant (1)
- antioxidative capacity (1)
- arabinoxylan (1)
- aristotelische Logik (1)
- arthropathies (1)
- aspect-oriented programming (1)
- asthenosphere (1)
- auxiliary control (1)
- beryllium (1)
- bicontinuous phase (1)
- bifurcation analysis (1)
- bilayer (1)
- biological age (1)
- biological robustness (1)
- biosensor (1)
- block copolymers (1)
- boundary value problems (1)
- brain-computer interface (1)
- brassinosteroid (1)
- bushbuck (1)
- capacity (1)
- cardiomyopathy (1)
- carnivory (1)
- chaetae (1)
- chaetal arrangement (1)
- chemical oxidative polymerization (1)
- chemoautotrophy (1)
- chimpanzee (1)
- chlorite (1)
- cholesterol (1)
- cis (1)
- climate change (1)
- cobalt porphyrin (1)
- colloids (1)
- coloration of terms (1)
- colored solid varieties (1)
- colour (1)
- common spatial patterns (1)
- comparative head morphology (1)
- competitiveness (1)
- complementation (1)
- complex systems (1)
- compositional map (1)
- computational biochemistry (1)
- condition factor (1)
- conditionals (1)
- contractor/provider split (1)
- control (1)
- copper (1)
- coral (1)
- corner Sobolev spaces with double weights (1)
- cortical network (1)
- crystal structure (1)
- cytochrome c (1)
- decision tree (1)
- degree of non-regulation (1)
- dehydration (1)
- delayed feedback (1)
- diet (1)
- dietary fibre (1)
- differential equation (1)
- drug discovery (1)
- dust (1)
- dynamic AOP (1)
- dynamic service adaptation (1)
- dynamical cluster (1)
- ejecta (1)
- electrochemistry (1)
- electron microprobe (1)
- electron transfer (1)
- ensuring state (1)
- event-related desynchronization (1)
- extremophile teleosts (1)
- financial constraints (1)
- finite state sequential transducers (1)
- flavonoid glycosides (1)
- flow system (1)
- fluid inclusions (1)
- force methods (1)
- forest model (1)
- fruit (1)
- functional connectivity (1)
- gemini surfactant (1)
- genetic algorithm (1)
- gold electrodes (1)
- gold nanoparticles (1)
- granite melts (1)
- green tea phenols (1)
- groundwater dynamics (1)
- growth-age (1)
- haemophilia (1)
- heart failure (1)
- high-frequency force (1)
- high-pressure metamorphism (1)
- horseradish peroxidase (1)
- human follicular fluid (1)
- hydrogen bonds (1)
- hydrogen peroxide (1)
- hydrogenation (1)
- hypoxia (1)
- ill-posed problem (1)
- immobilization (1)
- impaired glucose tolerance (1)
- incorporation (1)
- incremental SVM (1)
- indirect dependency (1)
- individual-based model (1)
- insulin (1)
- insulin resistance (1)
- integrated modelling (1)
- integrated river basin management (1)
- integrated river basin modelling (1)
- interference (1)
- intermittency (1)
- intrusion detection (1)
- inverse micelles (1)
- inverse modelling (1)
- inverse opals (1)
- isomerization (1)
- iterative regularization (1)
- landscape analysis (1)
- landscape modelling (1)
- leftmost derivations (1)
- leptin (1)
- limestone (1)
- linearly implicit time stepping methods (1)
- liquid chromatography-mass spectrometry (1)
- lithography (1)
- lithosphere (1)
- logging (1)
- long distance wh-movement (1)
- long-term data (1)
- low-frequency force (1)
- lysozyme (1)
- lysozyme activity (1)
- macrosurfactants (1)
- magma evolution (1)
- manifolds with conical singularities (1)
- marketization (1)
- mass flowering (1)
- mathematical model (1)
- mean residence time (1)
- melt inclusions (1)
- melt-melt immiscibility (1)
- metabolic regulation (1)
- metabolite profiling (1)
- metathesis (1)
- mica (1)
- micelles (1)
- minerals (1)
- miscibility (1)
- mobile Raman-microprobe (1)
- model description (1)
- molecular conformation (1)
- molybdenum cofactor deficiency (1)
- multi-hypersubstitutions (1)
- multinomial models (1)
- mutants (1)
- natriuretic peptide system (1)
- neogrammarians (1)
- noise (1)
- non-linear mixed effects (1)
- nonlinear dynamics (1)
- numerical weather prediction (1)
- nutrient retention (1)
- ongonite (1)
- online learning (1)
- ontogenesis (1)
- optimality theory (1)
- orangutan (1)
- ordering process (1)
- overlapping reading frames (1)
- pain (1)
- pantropical spotted dolphin (1)
- parametrices (1)
- particle morphology (1)
- pattern description (1)
- pattern-process interrelationship (1)
- peptide (1)
- peralkalinity (1)
- peraluminosity (1)
- period doubling (1)
- phase diffusion (1)
- photochromism (1)
- photonic crystal (1)
- phylogenesis (1)
- plant phenolic compounds (1)
- pollination (1)
- polycystic ovary syndrome (1)
- polypyrrole (1)
- post-collisional setting (1)
- primary metabolism (1)
- programmed grammars (1)
- proinsulin (1)
- proteasome (1)
- protein derivatization (1)
- protein digestibility (1)
- protein targeting (1)
- protein-phenol binding (1)
- proteome (1)
- provenance (1)
- pseudo-differential boundary value problems (1)
- radiation pressure (1)
- ratchets (1)
- reactive oxygen species (1)
- reasoning (1)
- recurrence plot (1)
- red wine (1)
- reef (1)
- regioselectivity (1)
- regularization (1)
- relationship banking (1)
- remote sensing (1)
- resistin (1)
- resolvents (1)
- retinol-binding protein (1)
- riparian zones (1)
- ruthenium (1)
- saliva proteins (1)
- salt stress (1)
- savanna (1)
- scientific communication (1)
- sealevel (1)
- self-assembly (1)
- semi-Lagrangian method (1)
- semi-arid hydrology (1)
- serum (1)
- service provider strategies (1)
- sexual dimorphism (1)
- shallow-water equations (1)
- shoaling (1)
- simulation (1)
- single-trial-analysis (1)
- size dependent mortality (1)
- size distribution (1)
- small and medium sized enterprises (1)
- soy (1)
- soy protein (1)
- species recognition (1)
- spectral theory (1)
- standardization (1)
- starch (1)
- starch phosphorylation (1)
- stars : Wolf-Rayet (1)
- stars : atmospheres (1)
- stars : early-type (1)
- stars : evolution (1)
- stars : individual : xi Per (1)
- stars : individual : zeta Oph (1)
- stars : individual : zeta Ori (1)
- stars : individual : zeta Pup (1)
- stars : mass-loss (1)
- stars : winds, outflows (1)
- state complexity (1)
- statistical physics (1)
- stereoselectivity (1)
- stochastic process (1)
- stochastic resonance (1)
- stochastics (1)
- subduction (1)
- sulfoxide (1)
- surface tension (1)
- systematics (1)
- systems biology (1)
- tandem sequence (1)
- tantalum (1)
- tectonophysics (1)
- teleseismic tomography (1)
- temporal discretization (1)
- thermodynamic modelling (1)
- thickness of the lithosphere (1)
- thin films (1)
- tomato (1)
- topological community (1)
- total phenol content (1)
- tragelaphini (1)
- transferhydrogenation (1)
- tree death (1)
- tropical rainforest (1)
- tryptophan quenching (1)
- type 2 diabetes mellitus (1)
- ultra heat treatment (1)
- ungulate behaviour (1)
- vanillin (1)
- vibrational resonance (1)
- vitamin A (1)
- water ice (1)
- water quality (1)
- water resources management (1)
- wavelet analysis (1)
- western blotting (1)
- wetlands (1)
- wh-scope marker (1)
- word-based morphology (1)
- working memory (1)
- ytterbian xenotime-(Y) (1)
Institut
- Institut für Physik und Astronomie (156)
- Institut für Biochemie und Biologie (133)
- Wirtschaftswissenschaften (88)
- Öffentliches Recht (74)
- Institut für Chemie (72)
- Institut für Geowissenschaften (67)
- Department Psychologie (65)
- Sozialwissenschaften (65)
- Institut für Romanistik (59)
- Institut für Informatik und Computational Science (54)
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence.
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence
A comparative study on the nutritional status of primiparous and multiparous women in the first trimester of pregnancy was conducted in the northeastern province of Thailand, Khon Kaen, to investigate differences in protein- energy-mal nutrition, iron deficiency anaemia, vitamin A deficiency and carotenoid status between both parity groups. 94 subjects were recruited at first attendance of antenatal clinic. Data about weight, height, haemoglobin and haematocrit were obtained from hospital records. Anthropometric measurements of mid-upper arm circumference and triceps skinfold were done on a sub sample. Retinol, carotenoids and alpha-tocopherol were analysed using a reversed-phase high- performance liquid chromatography method. Ferritin, transthyretin and retinol-binding protein were determined by enzyme- linked immunosorbent assay. Primiparous women showed lower body mass index, mid-upper arm circumference, corrected arm muscle area (P <0.001) as well as lower retinol, cholesterol and triceps skinfold (P <0.05). After adjusting for age and socio-economical status the significant difference persisted for all parameters but triceps skinfold. No significant differences of alpha-tocopherol, serum proteins, carotenoids and iron indices could be observed, even though a tendency to higher values for ferritin, haemoglobin and haematocrit was shown in multiparous women. Prevalence of protein-energy- malnutrition (body mass index <18.5 kg/m(2)) in the primiparous group was significantly higher compared to the multiparous group (P<0.05). Prevalence of protein-energy-malnutrition, iron deficiency anaemia and vitamin A deficiency were 15.1%, 6.3% and 3.3%, respectively, in the total study population. No differences between parity groups could be observed for prevalence of iron deficiency anaemia and vitamin A deficiency
Peptide microarrays displaying biologically active small synthetic peptides in a high-density format provide an attractive technology to probe complex samples for the presence and/or function of protein analytes. We present a new approach for manufacturing functional peptide microarrays for molecular immune diagnostics. Our method relies on the efficiency of site-specific solution-phase coupling of biotinylated synthetic peptides to NeutrAvidin (NA) and localized microdispensing of peptide-NA-complexes onto activated glass surfaces. Antibodies are captured in a sandwich manner between surface immobilized peptide probes and fluorescence-labeled secondary antibodies. Our work includes a total of 54 peptides derived from immunodominant linear epitopes of the T7 phage capsid protein, Herpes simplex virus glycoprotein D, c-myc protein, and three domains of the Human coronavirus polymerase polyprotein and their cognate mAbs. By using spacer molecules of different type and length for NA-mediated peptide presentation, we show that the incorporation of a minimum spacer length is imperative for antibody binding, whereas the peptide immobilization direction has only secondary importance for antibody affinity and binding. We further demonstrate that the peptide array is capable of detecting low-picomolar concentrations of mAbs in buffered solutions and diluted human serum with high specificity
Peptide microarrays with site-specifically immobilized synthetic peptides for antibody diagnostics
(2006)
Peptide microarrays bear the potential to discover molecular recognition events on protein level, particularly in the field of molecular immunology, in a manner and with an efficiency comparable to the performance of DNA microarrays. We developed a novel peptide microarray platform for the detection of antibodies in liquid samples. The system comprises site-specific solution phase coupling of biotinylated peptides to NeutrAvidin, localized microdispensing of peptide-NeutrAvidin conjugates onto activated glass slides and a fluorescence immuno sandwich assay format for antibody capture and detection. Our work includes synthetic peptides deduced from amino acid sequences of immunodominant linear epitopes, such as the T7 phage capsid protein, Herpes simplex virus glycoprotein D, c-myc protein and three domains of the Human coronavirus 229E polymerase polyprotein. We demonstrate that our method produces peptide arrays with excellent spot morphology which are capable of specific and sensitive detection of monoclonal antibodies from fluid samples.
The results of a quantum-mechanical study of vibrational relaxation of hydrogen adsorbed on a Si(100) surface with the multi-configurational time-dependent Hartree (MCTDH) method are presented. A two-dimensional subsystem is coupled non-linearly to a bath of harmonic oscillators (phonons of the Si bulk), and the relaxation of subsystem vibrations proceeds primarily via a two-phonon process. Characteristic times of the system evolution agree well with our previous perturbation theory study. The vibrational population decay is non-exponential, exhibiting pronounced recurrences due to finite bath size. The dependence of the lifetimes of the vibrational levels on the bath size and on the coupling details is investigated.
In this paper a perturbation-theory study of vibrational lifetimes for the bending and stretching modes of hydrogen adsorbed on a Si(100) surface is presented. The hydrogen-silicon interaction is treated with a semiempirical bond-order potential. Calculations are performed for H-Si clusters of different sizes. The finite lifetime is due to vibration-phonon coupling, which is assumed to be linear or bilinear in the phonon and nonlinear in the H-Si stretching and bending modes. Lifetimes and vibrational transition rates are evaluated with one- and two-phonon processes taken into account. Temperature effects are also discussed. In agreement with the experiment and previous theoretical treatment it is found that the H-Si (upsilon(s)=1) stretching vibration decays on a nanosecond timescale, whereas for the H-Si (upsilon(b)=1) bending mode a picosecond decay is predicted. For higher-excited vibrations, simple scaling laws are found if the excitation energies are not too large. The relaxation mechanisms for the excited H-Si stretching and the H-Si bending modes are analyzed in detail.
We propose a new autonomous dynamical system of dimension N=4 that demonstrates the regime of stable two- frequency motions and period-doubling bifurcations of a two-dimensional torus. It is shown that the period-doubling bifurcation of the two-dimensional torus is not followed by the resonance phenomenon, and the two-dimensional ergodic torus undergoes a period-doubling bifurcation. The interaction of two generators is also analyzed. The phenomenon of external and mutual synchronization of two-frequency oscillations is observed, for which winding number locking on a two- dimensional torus takes place
Seasonal, host sex and age-related variations in helminth egg and coccidian oocyst counts were investigated in a naturally infected wild bushbuck (Tragelaphus scriptus) population in Queen Elizabeth National Park, western Uganda from April 2000 to February 2002. The prevalence and mean intensity quantified as the number of eggs and oocysts per gram of faeces were taken as a measure of parasite burdens. Host sex and age-related differences in prevalence values were not found but the overall prevalence of Eimeria sp. was significantly higher during the rainy season, and peak counts were recorded either during or soon after a peak rainfall. A similar trend was observed for Moniezia spp., although the results were marginally not significant. There were also no significant differences in mean intensity values, relative to host sex, age or season.
Bushbuck (Tragelaphus scriptus) often deposit faeces at specific localised defecation sites (LDS). We tested whether LDS have a function in the context of parasite avoidance. In a population of bushbuck in Queen Elizabeth National Park, Uganda, seven radio-collared individuals were observed. We recorded feeding behaviour inside and outside LDS. Furthermore, pasture contamination with gastro-intestinal tract parasites inside and outside LDS was examined. There were significant differences between the expected and the observed feeding rates inside LDS, but, contrary to our prediction, the bushbuck increased their feeding rate inside LDS. There was no significant difference in the parasite contamination of pastures inside and outside LDS. We discuss the hypothesis that LDS mainly serve a social function in bushbuck communities, whereas parasite avoidance seems to play a minor or no role
Overriding plate thinning in subduction zones : localized convection induced by slab dehydration
(2006)
In subduction zones, many observations indicate that the backarc thermal state is particularly hot and that the upper lithosphere is thin, even if no recent extension episode has occurred. This might result from free thermal convection favored by low viscosities in the hydrated mantle wedge. We perform 2-D numerical experiments of the convective mantle wedge interaction with both the downgoing slab and the overriding plate to test this hypothesis, explore its physical mechanism, and assess its dependencies on some relevant rock properties. Water transfers across the subducting plate and the mantle wedge are explicitly modeled by including in the calculation realistic hydration/ dehydration reaction boundaries for a water-saturated mantle and oceanic crust. The rheology is non-Newtonian and temperature-, pressure-, and water content-dependent. For low strength reduction associated to water content, the upper plate is locally thinned by an enhanced corner flow. For larger strength reductions, small convection cells rapidly thin the upper plate ( in less than 15 Myr) over the area in the overriding lithosphere hydrated by slab-derived water fluxes. As a result, the thinned region location depends on the subducting plate thermal state, and it increases with high convergence rates and low subduction dip angles. Other simulations are performed to test the sole effect of hydrous rock weakening on the upper plate/mantle convective interaction. They show that the thinning process is not influenced by the corner flow, but develops at the favor of a decoupling level induced by the formation of hydroxylated minerals inside the hydrated lithosphere. The erosion mechanism identified in these simulations allows us to explain the characteristic duration of erosion as a function of the hydrous strength reduction. We find that the presence of amphibole in the upper lithosphere in significant proportions is required down to a temperature of about 980 degrees C, corresponding to an initial depth of similar to 70 km, to strongly decrease the strength of the base of the lithosphere and trigger a rapid erosion (< 15 Myr).
Recurrence plot analyses suggest a novel reference system involved in newborn spontaneous movements
(2006)
The movements of newborns have been thoroughly studied in terms of reflexes, muscle synergies, leg coordination, and target-directed arm/hand movements. Since these approaches have concentrated mainly on separate accomplishments, there has remained a clear need for more integrated investigations. Here, we report an inquiry in which we explicitly concentrated on taking such a perspective and, additionally, were guided by the methodological concept of home base behavior, which Ilan Golard developed for studies of exploratory behavior in animals. Methods from nonlinear dynamics, such as symbolic dynamics and recurrence plot analyses of kinematic data received from audiovisual newborn recordings, yielded new insights into the spatial and temporal organization of limb movements. In the framework of home base behavior, our approach uncovered a novel reference system of spontaneous newborn movements.