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Excerpt: The shrill sounds of the now seemingly outdated controversy between Gershom Scholem and Martin Buber at the beginning of the sixties are still in the minds of every student of Hasidic literature and thought. - The "Scholem-community" feels content and the "Buber-community" upset. We can summarize the case in a few words. Martin Buber, the pioneer of Hasidism in the Western World, held the position that whoever would want to understand Hasidism had to turn to Hasidic tale as here, in the tales of the Hasidim, real Hasidic life was to be found. Whereas in the Hasidic homilies we meet mere non-creative tradition especially in the form of Kabbalah. Buber did not totally deny the importance of the Hasidic Midrash but he regarded it just as a commentary, i.e. as secondhand material, whereas, in his view, the tale was a true mirror of real Hasidic life [...]
Several zwitterionic polymers were prepared by radical homopolymerization of surfactant monomers which bear diallyl, diene or vinylcyclopropane moieties. These polymer systems were complemented by alternating copolymers of appropriate zwitterionic vinyl compounds. Thus, polymers with reduced (as compared with simple vinylic homopolymers, or statistical copolymers) and well defined density of surfactant side groups are obtained. The solubilities found for these polymers are dominated by polymer geometry rather than by the balance of hydrophilic and hydrophobic fragments, thus corroborating a main-chain spacer model proposed recently. All water-soluble polymers exhibit characteristic features of classical polysoaps, as shown by surface tension measurements and by solubilization of hydrophobic dyes. In contrast, the water-insoluble copolymers are capable to form stable monolayers at the air-water interface.
Ziel dieses Aufsatzes ist es zu zeigen, daß und weshalb Intonationsmodelle, die die Prämissen des traditionellen systemisch-tonetischen Ansatzes teilen, ungeeignet sind für die Analyse natürlicher Sprachverwendung in konversationeller Interaktion. Insbesondere die Grundeinheit der 'Tpngruppe'/'Toneinheit'/'Intonationsphrase' wie auch die Analyse des 'Tonmusters' bzw. der letzten Tonhöhenbewegung der Einheit im Hinblick auf die Unterscheidung und Differenzierung von Satzarten bzw. Satzmodi sind auf die Analyse kontextfreier Sätze zugeschnitten und kaum auf die Verhältnisse der Sprachverwendung in natürlicher konversationeller Interaktion übertragbar. Eine alternative Analyse der Intonation als interaktiv relevantes Signalisierungssystem ermöglicht bessere und plausiblere Beschreibungen. Nleine alternative Konzeption basiert auf der empirischen Analyse eines Korpus natürlicher Daten aus informellen Alltagsgesprächen. Das Ergebnis dieser Analyse ist, daß Intonation als unabhängiges, autonomes Signalisierungssystem aufgefaßt werden muß. Für die derzeit üblichen Ansätze der phonologischen Intonationsforschung ergibt sich die Forderung nach noch stärkerer als bisher angenommener Modularisierung: Zwar steht die Wahl der Akzentstelle in systematischer Beziehung zu grammatischen Prinzipien und muß mit Bezug auf die Grammatik analysiert werden, aber die Wahl der Tonhöhenbewegung kann nicht mit Bezug auf die Grammatik erklärt werden: die letzte Tonhöhenbewegung unterscheidet nicht grammatisch relevante Satzarten/Satzmodi, sondern interaktiv relevante Aktivitätstypen in der konversationeilen Interaktion, die auch je unterschiedliehe sequentielle Implikationen für die konditioneil relevante Antwort haben.
Die Arbeit hat die Inhalte der Verbalflexion im Französischunterricht an Deutschsprachige und ihre Progression zum Gegenstand. Es wird ein von unbeabsichtigten Lücken freies und zugleich auf ein Minimum beschränktes System von temporalen und modalen Kategorien, Verbklassen und Regeln zur Bildung der zusammengesetzten Tempora und Modi sowie zur Angleichung des Participe passé vorgeschlagen. Die Notwendigkeit, die sprachlichen Lehrinhalte zu reduzieren, ohne die Äußerungsmöglichkeiten der Schüler auf bestimmte Themen, Situationen oder Absichten zu beschränken, wird belegt durch Lücken, z.T. überhöhte, z.T. in anderer Hinsicht korrekturbedürftige Pensen in Grammatiken für den Französischunterricht, in Lehrplänen und Lehrwerken. Der zweite Teil der Arbeit enthält präzise Empfehlungen für die chronologische Anordnung und Gruppierung der Lehrinhalte, da den Lehrplan- und Lehrwerkautoren bisher auch für die Planung der Progression verläßliche Grundlagen fehlten. Insgesamt soll die Arbeit einen nicht zeitgebundenen Beitrag zur Planung des Französischunterrichts und zugleich eine Dokumentation des Forschungsstandes darstellen, der in Schulgrammatiken, Lehrplänen und Lehrwerken der letzten 30 Jahre erreicht wurde.
This article describes recent achievements in the field of micellar polymers, or polysoaps. Taking advantage of zwitterionic model polymers, systematic variations of the molecular architecture have provided an improved understanding of the relationship between the molecular structure of the polymers and their key properties such as surface activity and solubilization capacity. Useful rules are established, which take into account much of the previous data in the literature.
This paper presents a new methodology for examining the phenomenon of subitizing. Subjects were presented with a standard numerosity-detection task but for a range of presentation times to allow Task-Accuracy Functions to be computed for individual subjects. The data appear to show a continuous change in processing for numerosities from 2 to 5 when the data are aggregated across subjects. At the level of individual subjects, there appear to be qualitative shifts in enumeration processing after 3 or 4 objects. The approach used in this experiment may be used to test the claim that subitizing is a distinct enumeration process that can be used for small numbers of objects.
Dieses Buch gibt einen Überblick über die Funktion der Sozialleistungen im betrieblichen Vergütungssystem. Es verdeutlicht, was bei der Vergabe der einzelnen Leistungsarten zu berücksichtigen ist, zeigt deren Vor- und Nachteile für Arbeitgeber und Arbeitnehmer auf und gibt Hinweise auf kostengünstige Zusatzleistungen, die im Vergleich zu teureren Lösungen höhere Wertschätzung genießen. Zahlreiche Beispiele aus der betrieblichen Praxis bieten dem Leser die Möglichkeit, Bewährtes in eigene Konzepte einzufügen sowie innovative Maßnahmen zu ergreifen, die ihm einen Wettbewerbsvorsprung auf dem Arbeitsmarkt für Fach- und Führungskräfte verleihen. „Sozialleistungsmanagement" wendet sich an Unternehmer, Personalleiter, Führungskräfte auf allen Ebenen sowie Personal- und Unternehmensberater, aber auch an Personal-und Betriebsräte, die im Hinblickauf das Machbare und auf neuere Entwicklungen bei Sozialleistungen auf dem laufenden bleiben wollen.
Sequential and coordinative complexity : age-based processing limitations in figural transformations
(1993)
Dimensions of cognitive complexity in figural transformations were examined in the context of adult age differences. Sequential complexity was manipulated through figural transformations of single objects in a multiple-object array. Coordinative complexity was induced through spatial or nonspatial transformations of the entire array. Results confirmed the prediction that age-related slowing is larger in coordinative complexity than in sequential complexity conditions. The effect was stable across 8 sessions (Experiment 1), was obtained when age groups were equated in accuracy with criterion-referenced testing (Experiment 2), and was corroborated by age-differential probabilities of error types (Experiments 1 and 2). A model is proposed attributing age effects under coordinative complexity to 2 factors: (a) basic-level slowing and (b) time-consuming reiterations through the processing sequence due to age-related working memory failures.
Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a
(1993)
Human anaphylatoxin C3a increases glycogenolysis in perfused rat liver. This action is inhibited by prostanoid synthesis inhibitors and prostanoid antagonists. Because prostanoids but not anaphylatoxin C3a can increase glycogenolysis in hepatocytes, it has been proposed that prostanoid formation in nonparenchymal cells represents an important step in the C3a-dependent increase in hepatic glycogenolysis. This study shows that (a) human anaphylatoxin C3a (0.1 to 10 mug/ml) dose-dependently increased prostaglandin D2, thromboxane B, and prostaglandin F2alpha formation in rat liver macrophages (Kupffer cells); (b) the C3a-mediated increase in prostanoid formation was maximal after 2 min and showed tachyphylaxis; and (c) the C3a-elicited prostanoid formation could be inhibited specifically by preincubation of C3a with carboxypeptidase B to remove the essential C-terminal arginine or by preincubation of C3a with Fab fragments of a neutralizing monoclonal antibody. These data support the hypothesis that the C3a-dependent activation of hepatic glycogenolysis is mediated by way of a C3a-induced prostanoid production in Kupffer cells.
This study explores learning-disabled students' academic and psychosocial adjustment as compared to their non-disabled classmates within the mainstream public education system in Greece. A brief description of the special education services in Greece is also presented. The sample of the study consisted of fifth and sixth grade elementary school students in northern Greece. The learning-disabled students were identified based on teachers' evaluation (N=30). The control group consisted of all classmates of these students (N=307). Teacher-, peer and self-ratings were used and achievement data were obtained. The learning-disabled students were found to exhibit various academic and psychosocial difficulties based on the perceptions of all raters. Implications of the findings are discussed.
A model for correct recall and intrusions in cued recall of word lists is introduced. Intrusions are false responses that were correct in an earlier list. The model assumes 3 exclusive states for memory traces after encoding: with a list tag (i.e., with information about list origin), without list tags, and missing. Across lists, a trace can lose its list tag or its content. For retrieval, an optimal strategy of response selection was assumed. Younger and older laboratory-trained mnemonists participated in 2 experiments in which recall of permutations of a single word list across a single set of cues was held constant with individually adjusted presentation times. With correct recall equated to younger adults, older adults were more susceptible to intrusions. Age differences were restricted to model parameters estimating the probability of generation of list tags. Alternative accounts of age differences in context memory are discussed.
Past research suggests that age differences in measures of cognitive speed contribute to differences in intellectual functioning between young and old adults. To investigate whether speed also predicts age-related differences in intellectual performance beyond age 70 years, tests indicating 5 intellectual abilities—speed, reasoning, memory, knowledge, and fluency—were administered to a close-to-representative, age-stratified sample of old and very old adults. Age trends of all 5 abilities were well described by a negative linear function. The speed-mediated effect of age fully explained the relationship between age and both the common and the specific variance of the other 4 abilities. Results offer strong support for the speed hypothesis of old age cognitive decline but need to be qualified by further research on the reasons underlying age differences in measures of speed.
Die Deutsche Geologische Gesellschaft (DGG) besitzt seit ihrer Gründung 1848 eine Bibliothek, die bis heute durch Schriftentausch ständig erweitert wird. Durch die geschichtlichen Entwicklungen in Deutschland befand sich der von 1848 bis 1944 angesammelte Bestand in Berlin und der ab 1945 erworbene Bestand in Hannover. 1992 wurde die Bibliothek der DGG der UB Potsdam als Dauerleihgabe übergeben und damit erstmals an einem Ort zusammengeführt. Beide Bibliotheksteile enthalten je eine umfangreiche Sammlung geologischer Karten. Während die Berliner Kartensammlung vor allem antiquarischen Wert hat, ist die Hannoveraner Sammlung von großem aktuellen Interesse. Wertvollster Teil der Kartensammlungen ist die weitgehendvollständig vorhandene Geologische Spezialkarte für Preußen im Maßstab 1:25000. Die Karten der Berliner Kartensammlung sind bibliographisch nur unvollständig verzeichnet, während die Hannoveraner Karten in einem Gruppenschlagwortkatalog erschlossen sind. Den Vertragsbedingungen entsprechend ist vorgesehen, beide Sammlungen retrospektiv einheitlich zu erschließen. Mittels Umfrage in 20 Bibliotheken wurden die verschiedenen Methoden der Sacherschließung von Kartensammlungen zusammengetragen. Es zeigte sich, daß diese je nach Bibliothekstyp sehr unterschiedlich sind. Für die sachliche Erschließung der DGG-Karten wird vorgeschlagen, die Aufstellungssystematik der Universitätsbibliothek Regensburg, Fachsystematik Geographie, anzuwenden, einen entsprechenden systematischen Katalog mit Verweisungen und Nebensystemstellen aufzubauen und ein Schlagwortregister nach RSWK/ SWD zu führen.
In perfused rat livers, infusion of prostaglandin F₂α (PGF₂α) or noradrenaline increased glucose and lactate output and reduced flow. Glucagon increased glucose output and decreased lactate output without influence on flow. Infusion of phorbol 13-myristate 14-acetate (PMA) for 20 min prior to these stimuli strongly inhibited the metabolic and hemodynamic effects of noradrenaline, reduced the metabolic actions of PGF₂α but did not alter the effects of glucagon. In isolated rat hepatocytes PGF₂α, noradrenaline and glucagon activated glycogen phosphorylase but only PGF₂α and noradrenaline increased intracellular inositol 1,4,5-1risphosphalc (InsP₃). The noradrenaline- or PGF₂α-elicited activation of glycogen phosphorylase and increase in InsP₃ were largely reduced after preincubation of the cells for 10 min with PMA, whereas the glucagon-mediated enzyme activation was not affected. In contra\t to PMA, the phorbol ester 4a-phorbol 13,14-didecanoate. which does not activate protein kinase C, did not attenuate the PGF₂α- and noradrenaline-elicited stimulation of glucose output, glycogen phosphorylase and InsP, formation. Stimulation of InsP₃ formation by AlF₄⁻, which activates phospholipase C independently of the receptor, was not attenuated by prior incubation with PMA. Plasma membranes purified from isolated hepatocytes had both a high-capacity, low-affinity and a low-capacity, high-affinity binding site for PGF₂α. The Kd of the high-capacity, low-affinity binding site was close to the concentration of PGF₂α that increased glycogen phosphorylase activity halfmaximally. Binding to the high-capacity, low-affinity binding site was enhanced by guanosine 5'- 0-(3-thio)triphosphate (GTP[S]). This high-capacity, low-affinity site might thus represent the receptor. The Bmax and Kd of the high-capacity site, as well as the enhancement by GTP[S] of PGF₂α binding to this site, remained unaffected by PMA pretreatment. It is concluded that, in hepatocytes, activation of protein kinase C by PMA interrupted the InsP₃-mediated signal pathway from PGF₂α via a PGF₂α receptor and phospholipase C to glycogen phosphorylase at a point distal of the receptor prior to phospholipase C.
Prostaglandin (PG)F₂α has previously been shown to increase glucose output from perfused livers and isolated hepatocytes, where it stimulated glycogen phosphorylase via an inositol-trisphosphatedependent signal pathway. In this study, PGF₂α binding sites on hepatocyte plasma membranes, that might represent the putative receptor, were characterized. Binding studies could not be performed with intact hepatocytes, because PGF₂α accumulated within the cells even at 4°C. The intracellular accumulation was an order of magnitude higher than binding to plasma membranes. Purified hepatocyte plasma membranes had a high-affinity/low-capacity and a low-affinity/highcapacity binding'site for PGF₂α. The respective binding constants for the high-affinity site were Kd = 3 nM and Bmax = 6 fmol/mg membrane protein, and for the low-affinity site Kd = 426 nM and Bmax = 245 fmol/mg membrane protein. Specific PGF₂α binding to the low-affinity site, but not to the high-affinity site, could be enhanced most potently by GTP[γS] followed by GDP[ϐS] and GTP, but not by ATP[γS] or GMP. PGF₂α competed most potently with [³H]PGF₂α for specific binding to hepatocyte plasma membranes, followed by PGD₂ and PGE₂. Since the low-affinity PGF₂α-binding site had a Kd in the concentration range in which PG had previously been shown to be half-maximally active, and since this binding site showed a sensitivity to GTP, it is concluded that it might represent the receptor involved in the PGF₂α signal chain in hepatocytes. A biological function of the high-affinity site is currently not known.
Prostaglandin E₂ has been reported both to stimulate glycogen-phosphorylase activity (glycogenolytic effect) and to inhibit the glucagon-stimulated glycogen-phosphorylase activity (antiglycogenolytic effect) in rat hepatocytes. It was the purpose of this study to resolve this apparent contradiction and to characterize the signalling pathways and receptor subtypes involved in the opposing prostaglandin E₂ actions. Prostaglandin E₂ (10 μM) increased glucose output, glycogen-phosphorylase activity and inositol trisphosphate formation in hepatocyte cell culture andor suspension. In the same systems, prostaglandin E₂ decreased the glucagon-stimulated (1 nM) glycogen-phosphorylase activity and cAMP formation. The signalling pathway leading to the glycogenolytic effect of PGE₂ was interrupted by incubation of the hepatocytes with 4P-phorbol 12-myristate 13-acetate (100 nM) for 10 min, while the antiglycogenolytic effect of prostaglandin E₂ was not attenuated. The signalling pathway leading to the antiglycogenolytic effect of prostaglandin E₂ was interrupted by an incubation of cultured hepatocytes with pertussis toxin (100 ng/ml) for 18 h, whereas the glycogenolytic effect of prostaglandin E₂ was enhanced. The EP₁/EP₃ prostaglandin-E₂-receptor-specific prostaglandin E₂ analogue Sulproston had a stronger glycogenolytic potency than the EP₃ prostaglandin-E₂-receptor-specific prostaglandin E₂ analogue Misoprostol. The antiglycogenolytic potency of both agonists was equal. It is concluded that the glycogenolytic and the antiglycogenolytic effects of prostaglandin E₂ are mediated via different signalling pathways in hepatocytes possibly involving EP₁ and EP₃ prostaglandin E₂ receptors, respectively.