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Prepubertal suicide attempts
(1994)
Privacy regulations and the physical distribution of heterogeneous data are often primary concerns for the development of deep learning models in a medical context. This paper evaluates the feasibility of differentially private federated learning for chest X-ray classification as a defense against data privacy attacks. To the best of our knowledge, we are the first to directly compare the impact of differentially private training on two different neural network architectures, DenseNet121 and ResNet50. Extending the federated learning environments previously analyzed in terms of privacy, we simulated a heterogeneous and imbalanced federated setting by distributing images from the public CheXpert and Mendeley chest X-ray datasets unevenly among 36 clients. Both non-private baseline models achieved an area under the receiver operating characteristic curve (AUC) of 0.940.94 on the binary classification task of detecting the presence of a medical finding. We demonstrate that both model architectures are vulnerable to privacy violation by applying image reconstruction attacks to local model updates from individual clients. The attack was particularly successful during later training stages. To mitigate the risk of a privacy breach, we integrated Rényi differential privacy with a Gaussian noise mechanism into local model training. We evaluate model performance and attack vulnerability for privacy budgets ε∈{1,3,6,10}�∈{1,3,6,10}. The DenseNet121 achieved the best utility-privacy trade-off with an AUC of 0.940.94 for ε=6�=6. Model performance deteriorated slightly for individual clients compared to the non-private baseline. The ResNet50 only reached an AUC of 0.760.76 in the same privacy setting. Its performance was inferior to that of the DenseNet121 for all considered privacy constraints, suggesting that the DenseNet121 architecture is more robust to differentially private training.
Objective: Questionnaires are often applied in sports psychology to measure a person's trait or state. However, the extent to which the questionnaire captures differences because of trait or state influences is often unclear. The latent state-trait (LST) theory offers the opportunity to separate both variance sources. This separation allows estimating specific reliability coefficients. Design: The present paper gives a theoretical introduction to LST and its basic ideas. Using a real data set with N = 156 athletes we exemplify the steps necessary to derive the LST coefficients. All athletes filled out a comprehensive inventory assessing competitive anxiety on two occasions. Method: The data are analysed with structural equation models based on LST principles. Results: The results confirm the questionnaire's trait saturation. Conclusion: Finally, results are discussed in light of practical and theoretical implications.
Rotations of the principal stress axes are observed as a result of fluid injection into reservoirs. We use a generic, fully coupled 3-D thermo-hydro-mechanical model to investigate systematically the dependence of this stress rotation on different reservoir properties and injection scenarios. We find that permeability, injection rate, and initial differential stress are the key factors, while other reservoir properties only play a negligible role. In particular, we find that thermal effects do not significantly contribute to stress rotations. For reservoir types with usual differential stress and reservoir treatment the occurrence of significant stress rotations is limited to reservoirs with a permeability of less than approximately 10(-12)m(2). Higher permeability effectively prevents stress rotations to occur. Thus, according to these general findings, the observed principal stress axes rotation can be used as a proxy of the initial differential stress provided that rock permeability and fluid injection rate are known a priori.
Iceland is located on the Mid-Atlantic Ridge which is the plate boundary between the Eurasian and the North American plates. It is one of the few places on earth where an active spreading centre is located onshore but the stress pattern has not been extensively investigated so far. In this paper we present a comprehensive compilation of the orientation of maximum horizontal stress (S-Hmax). In particular we interpret borehole breakouts and drilling induced fractures from borehole image logs in 57 geothermal wells onshore Iceland. The borehole results are combined with other stress indicators including earthquake focal mechanism solutions, geological information and overcoring measurements resulting in a dataset with 495 data records for the S-Hmax orientation. The reliability of each indicator is assessed according to the quality criteria of the World Stress Map project The majority of S-Hmax orientation data records in Iceland is derived from earthquake focal mechanism solutions (35%) and geological fault slip inversions (26%). 20% of the data are borehole related stress indicators. In addition minor shares of S-Hmax orientations are compiled, amongst others, from focal mechanism inversions and the alignment of fissure eruptions. The results show that the S-Hmax orientations derived from different depths and stress indicators are consistent with each other.
The resulting pattern of the present-day stress in Iceland has four distinct subsets of S-Hmax orientations. The S-Hmax orientation is parallel to the rift axes in the vicinity of the active spreading regions. It changes from NE-SW in the South to approximately N-S in central Iceland and NNW-SSE in the North. In the Westfjords which is located far away from the ridge the regional S-Hmax rotates and is parallel to the plate motion. (C) 2016 Elsevier B.V. All rights reserved.
On 27 December 2007, a 1.9 seismic event occurred within a dyke in the deep-level Mponeng Gold Mine, South Africa. From the seismological network of the mine and the one from the Japanese-German Underground Acoustic Emission Research in South Africa (JAGUARS) group, the hypocentral depth (3,509 m), focal mechanism and aftershock location were estimated. Since no mining activity took place in the days before the event, dynamic triggering due to blasting can be ruled out as the cause. To investigate the hypothesis that stress transfer, due to excavation of the gold reef, induced the event, we set up a small-scale high-resolution three-dimensional (3D) geomechanical numerical model. The model consisted of the four different rock units present in the mine: quartzite (footwall), hard lava (hanging wall), conglomerate (gold reef) and diorite (dykes). The numerical solution was computed using a finite-element method with a discretised mesh of approximately elements. The initial stress state of the model is in agreement with in situ data from a neighbouring mine, and the step-wise excavation was simulated by mass removal from the gold reef. The resulting 3D stress tensor and its changes due to mining were analysed based on the Coulomb failure stress changes on the fault plane of the event. The results show that the seismic event was induced regardless of how the Coulomb failure stress changes were calculated and of the uncertainties in the fault plane solution. We also used the model to assess the seismic hazard due to the excavation towards the dyke. The resulting curve of stress changes shows a significant increase in the last in front of the dyke, indicating that small changes in the mining progress towards the dyke have a substantial impact on the stress transfer.
We propose two methods that reduce the post-nonlinear blind source separation problem (PNL-BSS) to a linear BSS problem. The first method is based on the concept of maximal correlation: we apply the alternating conditional expectation (ACE) algorithm-a powerful technique from nonparametric statistics-to approximately invert the componentwise nonlinear functions. The second method is a Gaussianizing transformation, which is motivated by the fact that linearly mixed signals before nonlinear transformation are approximately Gaussian distributed. This heuristic, but simple and efficient procedure works as good as the ACE method. Using the framework provided by ACE, convergence can be proven. The optimal transformations obtained by ACE coincide with the sought-after inverse functions of the nonlinearitics. After equalizing the nonlinearities, temporal decorrelation separation (TDSEP) allows us to recover the source signals. Numerical simulations testing "ACE-TD" and "Gauss-TD" on realistic examples are performed with excellent results
A new efficient algorithm is presented for joint diagonalization of several matrices. The algorithm is based on the Frobenius-norm formulation of the joint diagonalization problem, and addresses diagonalization with a general, non- orthogonal transformation. The iterative scheme of the algorithm is based on a multiplicative update which ensures the invertibility of the diagonalizer. The algorithm's efficiency stems from the special approximation of the cost function resulting in a sparse, block-diagonal Hessian to be used in the computation of the quasi-Newton update step. Extensive numerical simulations illustrate the performance of the algorithm and provide a comparison to other leading diagonalization methods. The results of such comparison demonstrate that the proposed algorithm is a viable alternative to existing state-of-the-art joint diagonalization algorithms. The practical use of our algorithm is shown for blind source separation problems
Instrumental data show that the groundwater and lake levels in Northeast Germany have decreased over the past decades, and this process has accelerated over the past few years. In addition to global warming, the direct influence of humans on the local water balance is suspected to be the cause. Since the instrumental data usually go back only a few decades, little is known about the multidecadal to centennial-scale trend, which also takes long-term climate variation and the long-term influence by humans on the water balance into account. This study aims to quantitatively reconstruct the surface water areas in the Lower Havel Inner Delta and of adjacent Lake Gulpe in Brandenburg. The analysis includes the calculation of surface water areas from historical and modern maps from 1797 to 2020. The major finding is that surface water areas have decreased by approximately 30% since the pre-industrial period, with the decline being continuous. Our data show that the comprehensive measures in Lower Havel hydro-engineering correspond with groundwater lowering that started before recent global warming. Further, large-scale melioration measures with increasing water demands in the upstream wetlands beginning from the 1960s to the 1980s may have amplified the decline in downstream surface water areas.
The seismicity of the Kenya rift is characterized by high-frequency low-magnitude events concentrated along the rift axis. Its seismic character is typical for magmatically active continental rifts, where igneous material at a shallow depth causes extensive grid faulting and geothermal activity. Thermal overprinting and dike intrusion prohibit the buildup of large elastic strains, therefore prohibiting the generation of large-magnitude earthquakes. On 6 January 1928, the M-S 6.9 Subukia earthquake occurred on the Laikipia-Marmanet fault, the eastern rift-bounding structure of the central Kenya rift. It is the largest instrumentally recorded seismic event in the Kenya rift, standing in contrast to the current model of the rift's seismic character in which large earthquakes are not anticipated. Furthermore, the proximity of the ruptured fault and the rift axis is intriguing: The rift-bounding structure that ruptured in 1928 remains seismically active, capable of generating large-magnitude earthquakes, even though thermally weakened crust and better oriented structures are present along the rift axis nearby, prohibiting any significant buildup of elastic strain. We excavated the surface rupture of the 1928 Subukia earthquake to find evidence for preceding ground-rupturing earthquakes. We also made a total station survey of the site topography and mapped the site geology. We show that the Laikipia-Marmanet fault was repeatedly activated during the late Quaternary. We found evidence for six ground-rupturing earthquakes, including the 1928 earthquake. The topographic survey around the trench site revealed a degraded fault scarp of approximate to 7.5 m in height, offsetting a small debris slide. Using scarp-diffusion modeling, we estimated an uplift rate of U = 0.09-0.15 mm/yr, constraining the scarp age to 50-85 ka. Assuming an average fault dip of 55 degrees-75 degrees, the preferred uplift rate (0.15 mm/yr) accommodates approximately 10%-20% of the recent rate of extension (0.5 mm/yr) across the Kenya rift.
Questions of identity and provenance of minerals that are parts of masterpieces in museums have become increasingly important in mineralogical and historical studies. Detailed investigations of valuable and unique objects require on-site, nondestructive and noninvasive methods because touching or removing them may cause irreparable damage. A mobile Raman-microprobe has been used to meet these demands for truly in situ mineralogical studies of the large collection of minerals and rocks of the Prussian kings in the Grotto Hall (Grottensaal) of the New Palace (Neues Palais), Park Sanssouci in Potsdam. Minerals on the walls of the Grotto Hall were analyzed to identify them and thereby to complete the data bank of the collection. Fluid and solid inclusions in the interior of a large quartz crystal have been studied to provide evidence of the provenance of the crystal. The fluid inclusions contain aqueous saline solutions, whereas the solid inclusions are needles of anhydrite with a length of about 1.5 mm. The quartz probably originated from an area in the eastern Alps, from the surroundings of Bad Gastein, Austria. This is the first on-site and in situ study of inclusions below the surface of a mineral with a mobile Raman-microprobe outside a laboratory.
Thermobarometrical and mineral-chemical investigations by electron microprobe and LA-ICP-MS on a sillimanite- bearing pegmatoid from the Reinbolt Hills provide important constraints on the P-T-X-age relations of part of East Antarctica during Pan-African tectonism. U-Th-total Pb ages of monazite imply that the pegmatoid of originally Grenvillan age (zircon U-Pb age of ca. 900 Ma) underwent a major, late Pan-African (Cambrian) regional, granulite-facies metamorphism between 500 and 550 Ma. Most of the monazite formed during this event, as result of apatite metasomatism owing to infiltration of high-grade metamorphic fluids. Apatite-biotite and other mineral thermobarometers define the peak metamorphic temperatures and pressures with 850-950 degrees C and 0.8-1.0 GPa. The F-Cl-OH relations in apatite, and biotite, the chemistry of fluid inclusions and the presence of K-feldspar microveins suggest that the metasomatising fluid was a CO2-bearing, diluted KCl brine. The pegmatoid is the first record of monazite-(Ce) formed from fluorapatite that is rich in U (up to 2.6 Wt% UO2) and possesses Th/U ratios <1 (0.09 on average). These chemical signatures are direct reflection of the U and Th concentration patterns in the parental fluorapatite
The 10th edition of the International Congress on the Application of Raman Spectroscopy in Art and Archaeology (RAA2019) was held in Potsdam (Germany) from 3 to 7 September 2019, with eight keynote lectures, 35 oral presentations and 18 Poster Presentations. The number of active participants was 68 delegates from 20 countries among the 236 authors that presented at least one work.
Microviridins are ribosomally synthesized tricyclic depsipeptides produced by different genera of cyanobacteria. The prevalence of the microviridin gene clusters and the natural diversity of microviridin precursor sequences are currently unknown. Screening of laboratory strains and field samples of the bloom-forming freshwater cyanobacterium Microcystis via PCR revealed global occurrence of the microviridin pathway and an unexpected natural variety. We could detect 15 new variants of the precursor gene mdnA encoding microviridin backbones that differ in up to 4 amino acid positions from known isoforms of the peptide. The survey not only provides insights into the versatility of the biosynthetic enzymes in a closely related group of cyanobacteria, but also facilitates the discovery and characterization of cryptic microviridin variants. This is demonstrated for microviridin L in Microcystis aeruginosa strain NIES843 and heterologously produced variants.