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Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.
Welfare beyond consumption
(2020)
In developed regions worldwide, so-called anti-consumers are increasingly resisting high-level consumption lifestyles or shifting to alternative forms of consumption. A general reduction in consumption levels is considered necessary to attain global sustainability goals. However, knowledge regarding the factors driving people to deliberately consume less and how anti-consumption affects individuals' well-being is limited. Against this background, this study considers the influence of human values and the well-being effects of two types of anti-consumption: voluntary simplicity and collaborative consumption. Based on representative data from the US (N = 1075) and Germany (N = 1070), the findings show that the two anti-consumption types do not reduce the well-being of individuals' but in some cases, even improve it, which suggests that lowering consumption can not only help protect environmental resources but also serve the greater good of society. In particular, this relationship holds among collaborative consumers with a strong need for cognition, i.e., a cognitive thinking style that involves a high level of decision control. According to the study results, opposite value orientations are the drivers of voluntary simplicity and collaborative consumption (i.e., a focus on self-transcendence versus self-enhancement). These findings are comparable in both countries; however, the strength of the effects differs.
Weltraumrecht
(2020)
Technology pivots were designed to help digital startups make adjustments to the technology underpinning their products and services. While academia and the media make liberal use of the term "technology pivot," they rarely align themselves to Ries' foundational conceptualization. Recent research suggests that a more granulated conceptualization of technology pivots is required. To scientifically derive a comprehensive conceptualization, we conduct a Delphi study with a panel of 38 experts drawn from academia and practice to explore their understanding of "technology pivots." Our study thus makes an important contribution to advance the seminal work by Ries on technology pivots.
What Colin Reynolds could tell us about nutrient limitation, N:P ratios and eutrophication control
(2020)
Colin Reynolds exquisitely consolidated our understanding of driving forces shaping phytoplankton communities and those setting the upper limit to biomass yield, with limitation typically shifting from light in winter to phosphorus in spring. Nonetheless, co-limitation is frequently postulated from enhanced growth responses to enrichments with both N and P or from N:P ranging around the Redfield ratio, concluding a need to reduce both N and P in order to mitigate eutrophication. Here, we review the current understanding of limitation through N and P and of co-limitation. We conclude that Reynolds is still correct: (i) Liebig's law of the minimum holds and reducing P is sufficient, provided concentrations achieved are low enough; (ii) analyses of nutrient limitation need to exclude evidently non-limiting situations, i.e. where soluble P exceeds 3-10 mu g/l, dissolved N exceeds 100-130 mu g/l and total P and N support high biomass levels with self-shading causing light limitation; (iii) additionally decreasing N to limiting concentrations may be useful in specific situations (e.g. shallow waterbodies with high internal P and pronounced denitrification); (iv) management decisions require local, situation-specific assessments. The value of research on stoichiometry and co-limitation lies in promoting our understanding of phytoplankton ecophysiology and community ecology.
Giant earthquakes with magnitudes above 8.5 occur only in subduction zones. Despite the developments made in observing large subduction zone earthquakes with geophysical instruments, the factors controlling the maximum size of these earthquakes are still poorly understood. Previous studies have suggested the importance of slab shape, roughness of the plate interface contact, state of the strain in the upper plate, thickness of sediments filling the trenches, and subduction rate. Here, we present 2-D cross-scale numerical models of seismic cycles for subduction zones with various geometries, subduction channel friction configurations, and subduction rates. We found that low-angle subduction and thick sediments in the subduction channel are the necessary conditions for generating giant earthquakes, while the subduction rate has a negligible effect. We suggest that these key parameters determine the maximum magnitude of a subduction earthquake by controlling the seismogenic zone width and smoothness of the subduction interface. This interpretation supports previous studies that are based upon observations and scaling laws. Our modeling results also suggest that low static friction in the sediment-filled subduction channel results in neutral or moderate compressive deformation in the overriding plate for low-angle subduction zones hosting giant earthquakes. These modeling results agree well with observations for the largest earthquakes. Based on our models we predict maximum magnitudes of subduction earthquakes worldwide, demonstrating the fit to magnitudes of all giant earthquakes of the 20th and 21st centuries and good agreement with the predictions based on statistical analyses of observations.
When participants in an experiment have to name pictures while ignoring distractor words superimposed on the picture or presented auditorily (i.e., picture-word interference paradigm), they take more time when the word to be named (or target) and distractor words are from the same semantic category (e.g., cat-dog). This experimental effect is known as the semantic interference effect, and is probably one of the most studied in the language production literature. The functional origin of the effect and the exact conditions in which it occurs are however still debated. Since Lupker (1979) reported the effect in the first response time experiment about 40 years ago, more than 300 similar experiments have been conducted. The semantic interference effect was replicated in many experiments, but several studies also reported the absence of an effect in a subset of experimental conditions. The aim of the present study is to provide a comprehensive theoretical review of the existing evidence to date and several Bayesian meta-analyses and meta-regressions to determine the size of the effect and explore the experimental conditions in which the effect surfaces. The results are discussed in the light of current debates about the functional origin of the semantic interference effect and its implications for our understanding of the language production system.
Aim
Although research and clinical definitions of psychotherapeutic competence have been proposed, less is known about the layperson perspective. The aim was to explore the views of individuals with different levels of psychotherapy experience regarding what-in their views-constitutes a competent therapist.
Method
In an online survey, 375 persons (64% female, mean age 33.24 years) with no experience, with professional experience, or with personal pre-experience with psychotherapy participated. To provide low-threshold questions, we first presented two qualitative items (i.e. "In your opinion, what makes a good/competent psychotherapist?"; "How do you recognize that a psychotherapist is not competent?") and analysed them using inductive content analysis techniques (Mayring, 2014). Then, we gave participants a 16-item questionnaire including items from previous surveys and from the literature and analysed them descriptively.
Results
Work-relatedprinciples, professionalism, personalitycharacteristics, caringcommunication, empathy and understandingwere important categories of competence. Concerning the quantitative questions, most participants agreed with items indicating that a therapist should be open, listen well, show empathy and behave responsibly.
Conclusion
Investigating layperson perspectives suggested that effective and professional interpersonal behaviour of therapists plays a central role in the public's perception of psychotherapy.
Taking up some of W.'s paradoxical remarks about the existence of 'mental things' the paper investigates, what exactly he is criticizing. After a discussion of the mistaken idea of a private baptizing of one's own 'mental events' W.'s general criticism of the 'object-and-name model' is treated with a view on the consequences it has for our understanding of the mental. This treatment includes a discussion of figurative kinds of language use as well as a discussion of the difference between 'things' and 'objects of reference': With respect to figurative uses of language it often makes no sense to treat constituent expressions as names of objects, and not all objects of reference are things in an unproblematic ordinary-life sense. So what at first sight appears to be a limitation of our understanding of the nature of an object and consequently seems to ask for more empirical research often turns out to be a limitation of our understanding of how we use our language. The paper concludes that one important aspect of what the later W. opposes is dualism: The mental cannot be conceived of as an additional 'something' a description of which could be just added to a description of a person as a physical being. Thus W.'s anti-dualism can also be read as turning against a dualism in his Tractatus: The mental realm as well as other provinces of `the higher' are no longer seen as areas of entities about which we have to be silent.
When pandemic hits
(2020)
The governmental lockdowns related to the COVID-19 pandemic have forced people to change their behavior in many ways including changes in exercise. We used the brief window of global lockdown in the months of March/April/May 2020 as an opportunity to investigate the effects of externally imposed restrictions on exercise-related routines and related changes in subjective well-being. Statistical analyses are based on data from 13,696 respondents in 18 countries using a cross-sectional online survey. A mixed effects modeling approach was used to analyze data. We tested whether exercise frequency before and during the pandemic would influence mood during the pandemic. Additionally, we used the COVID-19 pandemic data to build a prediction model, while controlling for national differences, to estimate changes in exercise frequency during similar future lockdown conditions depending on prelockdown exercise frequency. According to the prediction model, those who rarely exercise before a lockdown tend to increase their exercise frequency during it, and those who are frequent exercisers before a lockdown tend to maintain it. With regards to subjective well-being, the data show that those who exercised almost every day during this pandemic had the best mood, regardless of whether or not they exercised prepandemic. Those who were inactive prepandemic and slightly increased their exercise frequency during the pandemic, reported no change in mood compared to those who remained inactive during the pandemic. Those who reduced their exercise frequency during the pandemic reported worse mood compared to those who maintained or increased their prepandemic exercise frequency. This study suggests that under similar lockdown conditions, about two thirds of those who never or rarely exercise before a lockdown might adopt an exercise behavior or increase their exercise frequency. However, such changes do not always immediately result in improvement in subjective well-being. These results may inform national policies, as well as health behavior and exercise psychology research on the importance of exercise promotion, and prediction of changes in exercise behavior during future pandemics.
In this paper, we move from the large strand of research that looks at evidence of climate migration to the questions: who are the climate migrants? and where do they go? These questions are crucial to design policies that mitigate welfare losses of migration choices due to climate change. We study the direct and heterogeneous associations between weather extremes and migration in rural India. We combine ERAS reanalysis data with the India Human Development Survey household panel and conduct regression analyses by applying linear probability and multinomial logit models. This enables us to establish a causal relationship between temperature and precipitation anomalies and overall migration as well as migration by destination. We show that adverse weather shocks decrease rural-rural and international migration and push people into cities in different, presumably more prosperous states. A series of positive weather shocks, however, facilitates international migration and migration to cities within the same state. Further, our results indicate that in contrast to other migrants, climate migrants are likely to be from the lower end of the skill distribution and from households strongly dependent on agricultural production. We estimate that approximately 8% of all rural-urban moves between 2005 and 2012 can be attributed to weather. This figure might increase as a consequence of climate change. Thus, a key policy recommendation is to take steps to facilitate integration of less educated migrants into the urban labor market.
Who makes the world?
(2020)
In this essay, we consider the role of academics as change-makers. There is a long line of reflection about academics' sociopolitical role(s) in international relations (IR). Yet, our attempt differs from available considerations in two regards. First, we emphasize that academics are not a homogenous group. While some keep their distance from policymakers, others frequently provide policy advice. Hence, positions and possibilities of influence differ. Second, our argument is not oriented towards the past but the future. That is, we develop our reflections on academics as change-makers by outlining the vision of a 'FutureLab', an innovative, future forum that brings together different world-makers who are united in their attempt to improve 'the world'. Our vision accounts for current, perhaps alarming trends in academia, such as debates about the (in)ability to confront post-truth politics. Still, it is a (critically) optimistic one and can be read as an invitation for experimentation. Finally, we sympathize with voices demanding the democratization of academia and find that further cross-disciplinary dialogues within academia and dialogues between different academics, civil society activists and policymakers may help in finding creditable solutions to problems such as climate change and populism.
Who owns REDD+?
(2020)
The question of who is entitled to benefit from transactions under the United Nations framework to reduce emissions from deforestation and forest degradation (REDD+) remains one of the most controversial issues surrounding cooperative efforts to reduce deforestation in developing countries. REDD+ has been conceived as an international framework to encourage voluntary efforts in developing countries to reduce greenhouse gas emissions and enhance carbon removals from forest activities. It was designed as an international framework under the United Nations Framework Convention on Climate Change (UNFCCC) to enable the generation of emission reductions and removals (ERRs) at the national-and, provisionally, the subnational-level and is, thus, primarily a creature of international law. However, in defining forest carbon ERRs, the international framework competes with national emission trading systems and domestic REDD+ legislation as well as private standards that define units traded on the voluntary carbon market. As results-based and carbon market systems emerge, the question remains: Who can claim participation in REDD+ and voluntary carbon market projects? The existence of different international, national and private standards that value ERRs poses a challenge to countries that participate in REDD+ as well as to communities and private actors participating in voluntary carbon market projects. This paper seeks to clarify the nature and limitation of rights pertaining to REDD+ market transactions. It also links the notion of carbon rights to both carbon markets and government's decision on benefit sharing. Applying a legal lens, this paper helps to understand the various claims and underlying rights to participate in REDD+ transactions and addresses ambiguities that can lead to conflict around REDD+ implementation. The definition of carbon rights and the legal nature of carbon credits depend on local law and differ between countries. However, by categorizing carbon rights, the paper summarizes several legal considerations that are relevant for regulating REDD+ and sharing the financial benefits of transacting ERRs.
Who’s to Blame?
(2020)
The main aim of this paper is to investigate how sexist ideology distorts our conceptions of sexual violence and the hermeneutical gaps such an ideology yields. I propose that we can understand the problematic issue of hermeneutical gaps about sexual violence with the help of Fricker’s theory of hermeneutical injustice. By distinguishing between hermeneutical injustice and hermeneutical misfire, we can distinguish between the hermeneutical gap and its consequences for the victim of sexual violence and those of the perpetrator of such violence. I then argue that perpetrators are both morally responsible and accountable for their acts, even if they are the result of a hermeneutical misfire. Ultimately, I show that with regard to sexual violence, we should opt for accountability to change the behaviour of the perpetrator and the social structure. Content warning: The paper discusses sexual violence and difficulties conceptualising experiences of such violence.
During the last decade, intracellular actin waves have attracted much attention due to their essential role in various cellular functions, ranging from motility to cytokinesis. Experimental methods have advanced significantly and can capture the dynamics of actin waves over a large range of spatio-temporal scales. However, the corresponding coarse-grained theory mostly avoids the full complexity of this multi-scale phenomenon. In this perspective, we focus on a minimal continuum model of activator–inhibitor type and highlight the qualitative role of mass conservation, which is typically overlooked. Specifically, our interest is to connect between the mathematical mechanisms of pattern formation in the presence of a large-scale mode, due to mass conservation, and distinct behaviors of actin waves.
This article examines the effect of parental socialization and interest in politics on entering and staying in public service careers. We incorporate two related explanations, yet commonly used in different fields of literature, to explain public sector choice. First, following social learning theory, we hypothesize that parents serve as role models and thereby affect their children's sector choice. Additionally, we test the hypothesis that parental socialization leads to a longer stay in public sector jobs while assuming that it serves as a buffer against turnover. Second, following public service motivation process theory, we expect that 'interest in politics' is influenced by parental socialization and that this concept, in turn, leads to a public sector career. A representative set of longitudinal data from the Swiss household panel (1999-2014) was used to analyse these hypotheses (n = 2,933, N = 37,328). The results indicate that parental socialization serves as a stronger predictor of public sector choice than an interest in politics. Furthermore, people with parents working in the public sector tend to stay longer in their public sector jobs. Points for practitioners For practitioners, the results of this study are relevant as they highlight the limited usefulness of addressing job applicants' interest in politics in the recruitment process. Human resources managers who want to ensure a public-service-motivated workforce are therefore advised to focus on human resources activities that stimulate public service motivation after job entry. We also advise close interaction between universities and public organizations so that students develop a realistic picture of the government as a future employer and do not experience a 'reality shock' after job entry.
Width control on event-scale deposition and evacuation of sediment in bedrock-confined channels
(2020)
In mixed bedrock-alluvial rivers, the response of the system to a flood event can be affected by a number of factors, including coarse sediment availability in the channel, sediment supply from the hillslopes and upstream, flood sequencing and coarse sediment grain size distribution. However, the impact of along-stream changes in channel width on bedload transport dynamics remains largely unexplored. We combine field data, theory and numerical modelling to address this gap. First, we present observations from the Daan River gorge in western Taiwan, where the river flows through a 1 km long 20-50 m wide bedrock gorge bounded upstream and downstream by wide braidplains. We documented two flood events during which coarse sediment evacuation and redeposition appear to cause changes of up to several metres in channel bed elevation. Motivated by this case study, we examined the relationships between discharge, channel width and bedload transport capacity, and show that for a given slope narrow channels transport bedload more efficiently than wide ones at low discharges, whereas wider channels are more efficient at high discharges. We used the model sedFlow to explore this effect, running a random sequence of floods through a channel with a narrow gorge section bounded upstream and downstream by wider reaches. Channel response to imposed floods is complex, as high and low discharges drive different spatial patterns of erosion and deposition, and the channel may experience both of these regimes during the peak and recession periods of each flood. Our modelling suggests that width differences alone can drive substantial variations in sediment flux and bed response, without the need for variations in sediment supply or mobility. The fluctuations in sediment transport rates that result from width variations can lead to intermittent bed exposure, driving incision in different segments of the channel during different portions of the hydrograph.