Refine
Year of publication
Document Type
- Article (141)
- Postprint (13)
- Conference Proceeding (7)
- Monograph/Edited Volume (6)
- Review (3)
- Other (2)
Is part of the Bibliography
- yes (172)
Keywords
- vitamin A (8)
- Vitamin A (7)
- HPLC (5)
- dogs (5)
- retinol (5)
- retinol-binding protein 4 (4)
- Biomarker (3)
- Blood (3)
- Emulsion (3)
- RBP4 (3)
- Retinol (3)
- Stability (3)
- iCheck (3)
- mass spectrometry (3)
- protein (3)
- proteinuria (3)
- transthyretin (3)
- Anemia (2)
- Bioavailability (2)
- C-reactive protein (2)
- COVID 19 (2)
- Cattle (2)
- Christentum (2)
- Cow-side assay (2)
- Dogs (2)
- Donors (2)
- Ernährungsgewohnheit (2)
- Ferritin (2)
- Hemoglobin (2)
- Iron deficiency anemia (2)
- Islam (2)
- Judentum (2)
- LC-MRM-MS (2)
- Lymphocytes (2)
- Method comparison (2)
- Neutrophils (2)
- Religiöses Leben (2)
- Reticulocytes (2)
- Retinyl esters (2)
- SDS-PAGE (2)
- Speisegebot (2)
- TTR (2)
- Whey protein (2)
- binding (2)
- c. elegans (2)
- carotenoids (2)
- carotenoids bioavailability (2)
- cells (2)
- disease (2)
- force-field (2)
- glomerular filtration rate (2)
- kidney transplantation (2)
- life-span (2)
- lutein (2)
- menadione (2)
- method comparison (2)
- monitoring (2)
- n-acetyl-cysteine (2)
- peptides markers (2)
- plasma (2)
- proteome (2)
- rapid test kit (2)
- relative quantification (2)
- renal disease (2)
- s-glutathionylation (2)
- wheat cultivars (2)
- α-amylase/trypsin inhibitors (2)
- 3,4-didehydroretinol (1)
- AMD (1)
- AOAC (1)
- Albumin (1)
- Antioxidant capacity (1)
- Asian subjects (1)
- Birds of prey (1)
- Body composition (1)
- Cameroon (1)
- Carotene supplementation (1)
- Carotenoid (1)
- Chad (1)
- Dairy cow (1)
- Diarrhoea (1)
- Distal tubules (1)
- Dog growth (1)
- Energy intake (1)
- FGF23 (1)
- Faecal bacteria (1)
- First ovulation (1)
- First trimester (1)
- Foal (1)
- Fruits (1)
- GC gene (1)
- GC-globulin (1)
- HOMA-IR (1)
- Hepatic enzyme (1)
- Hypertriglyceridemia (1)
- IGF-1 (1)
- Inflammation (1)
- Intestinal absorption (1)
- Iodization (1)
- Liver function (1)
- Low birth weight (1)
- Lutein (1)
- Lutein ester (1)
- MCT oil (1)
- Marker (1)
- Mass spectrometry (1)
- Milk (1)
- New World camelids (1)
- PlGF (1)
- Plasma concentration (1)
- Point of Care Assay and Vitamin A (1)
- Post-translational modifications (1)
- Pregnancy (1)
- Preterm infant (1)
- Proteinuria (1)
- Proteome (1)
- Puppies (1)
- Raman spectroscopy (1)
- Relative dose response test (1)
- Reproductive performance (1)
- Retinol-binding protein (1)
- Small for gestational age (1)
- Species differences (1)
- Spectrophotometry (1)
- Squashes pulp (1)
- Tagetes (1)
- Thai population (1)
- Tocotrienols (1)
- Type 2 diabetes (1)
- UV light (1)
- Urine excretion (1)
- Very low birth weight infant (1)
- Vitamin A supplementation (1)
- Yolk (1)
- a-tocopherol (1)
- alpha-Tocopherol (1)
- amylase activity (1)
- antioxidant capacity (1)
- antioxidants (1)
- bioavailability (1)
- birds of prey (1)
- body composition (1)
- bone mineral density (1)
- carotene (1)
- carotenoid (1)
- chimpanzee (1)
- chronic kidney-disease (1)
- colostrum (1)
- cow-side assay (1)
- deficiency (1)
- diet (1)
- diet selection (1)
- dog (1)
- dog growth (1)
- dosage recommendation (1)
- egg yolk (1)
- energy intake (1)
- fat-soluble vitamin (1)
- first trimester (1)
- foal (1)
- fortification (1)
- free radicals (1)
- fried (1)
- gestational diabetes mellitus (GDM) (1)
- green tea phenols (1)
- growth-factor 23 (1)
- haemodialysis (1)
- human follicular fluid (1)
- hypercalciuria (1)
- hypertension (1)
- inflammation (1)
- insulin (1)
- intestinal absorption (1)
- iodine (1)
- kidney (1)
- kidney dysfunction (1)
- large for gestational age fetus (LGA) (1)
- lower nephron (1)
- lutein ester (1)
- macular pigment density (1)
- malnutrition (1)
- mare (1)
- metabolic syndrome (1)
- micronutrient deficiencies (1)
- micronutrients (1)
- mortality (1)
- nomadic pastoralist (1)
- nutritional supplements (1)
- omega-3 fatty acids (1)
- orangutan (1)
- orphan crops (1)
- osteoporosis (1)
- palm oil (1)
- parathyroid-hormone (1)
- peptide (1)
- phosphorus (1)
- polymorphism (1)
- polyphenols (1)
- post-menopausal Thai women (1)
- post-translational modifications (1)
- potassium iodate (1)
- preterm infant (1)
- protein microheterogeneity (1)
- protein-phenol binding (1)
- puppies (1)
- quality control (1)
- reflection spectroscopy (1)
- regulatory monitoring (1)
- relative dose response test (1)
- renal function (1)
- retinol (ROH) (1)
- retinol binding protein 4 (1)
- retinol-binding protein (1)
- retinyl esters (1)
- retinyl palmitate (1)
- ruminants (1)
- sFlt-1 (1)
- saliva proteins (1)
- salivary proteins (1)
- salt (1)
- secretion (1)
- serum (1)
- serum retinol binding protein (RBP4) (1)
- single nucleotide polymorphism (1)
- skin (1)
- species differences (1)
- spectrophotometry (1)
- steam-dried (1)
- steamed (1)
- sudden death (1)
- tannin-protein interaction (1)
- tocopherol (1)
- tocotrienols (1)
- transthyretin (TTR) (1)
- tryptophan quenching (1)
- type 2 diabetes (1)
- type 2 diabetes mellitus (1)
- underutilized species (1)
- urinary ph (1)
- urine (1)
- vegetables (1)
- vitamin (1)
- vitamin A deficiency (1)
- vitamin D binding protein (1)
- vitamin D-binding protein (1)
- vitamins (1)
- yolk (1)
- zinc/iron supplementation (1)
Institute
- Institut für Ernährungswissenschaft (158)
- Mathematisch-Naturwissenschaftliche Fakultät (5)
- Institut für Biochemie und Biologie (4)
- Institut für Jüdische Studien und Religionswissenschaft (2)
- Institut für Jüdische Theologie (2)
- Institut für Lebensgestaltung-Ethik-Religionskunde (2)
- Department Psychologie (1)
- Department Sport- und Gesundheitswissenschaften (1)
- Institut für Geowissenschaften (1)
Hässlich aber gut
(2024)
Du sollst nicht essen
(2024)
Zwar sind Menschen biologisch gesehen Allesesser, dennoch gibt es keine Gemeinschaft, die alle ihr zur Verfügung stehenden Nahrungsmittel voll ausschöpft. Immer wird etwas nicht gegessen. Warum wir nicht essen, was wir nicht essen – das beleuchtet dieser Sammelband aus neuro-, ernährungs-, gesellschafts- und religionswissenschaftlicher Perspektive. Ein „religiöser Nutriscore“ gibt Auskunft über die wichtigsten Verzichtsregeln in Judentum, Christentum und Islam. Eine Fotostrecke veranschaulicht, wie bestimmte Speisen zu Festen und Feiertagen zu einem heiligen Essen werden. Nicht zuletzt werden Wege aufgezeigt, wie Menschen, die verschiedene Speiseregeln befolgen, dennoch zusammen essen können – inklusive Praxistest in der Unimensa.
Du sollst nicht essen
(2024)
Zwar sind Menschen biologisch gesehen Allesesser, dennoch gibt es keine Gemeinschaft, die alle ihr zur Verfügung stehenden Nahrungsmittel voll ausschöpft. Immer wird etwas nicht gegessen. Warum wir nicht essen, was wir nicht essen – das beleuchtet dieser Sammelband aus neuro-, ernährungs-, gesellschafts- und religionswissenschaftlicher Perspektive. Ein „religiöser Nutriscore“ gibt Auskunft über die wichtigsten Verzichtsregeln in Judentum, Christentum und Islam. Eine Fotostrecke veranschaulicht, wie bestimmte Speisen zu Festen und Feiertagen zu einem heiligen Essen werden. Nicht zuletzt werden Wege aufgezeigt, wie Menschen, die verschiedene Speiseregeln befolgen, dennoch zusammen essen können – inklusive Praxistest in der Unimensa.
To study the role of the TTR-RBP4-ROH complex components (transthyretin, serum retinol binding protein, retinol) and of angiogenic factors PlGF (placental growth factor) and sFlt-1 (soluble fms-like tyrosine kinase-1) in pregnancies complicated by small for gestational age infants (SGA). Case control study conducted on maternal serum collected between 11 + 0 to 13 + 6 weeks of gestation. TTR, RBP4, ROH, PlGF and sFlt-1 were measured in SGA patients (birth weight < 10%) who delivered at term (n = 37) and before 37 weeks of gestation (n = 17) and in a matched control group with uneventful pregnancies (n = 37). We found decreased RBP4 in SGA patients that delivered fetuses < 3% and in fetuses delivered after the 37 weeks of gestation compared to controls [1.50 (95% CI 1.40-1.75) vs 1.62 (95% CI 1.47-1.98), p < 0.05]. Further, we found lower PlGF and sFlt-1 concentrations in SGA that delivered before 37 weeks of gestation compared to controls (respectively, PIGF and sFlt-1: 39.7 pg/ml (95% CI 32.3-66.3) vs 62.9 pg/ml (95% CI 45.2-78.4) and 906 pg/ml (95% CI 727-1626) vs 1610 pg/ml (95% CI 1088-212), p < 0.05). First trimester maternal serum RBP4 and angiogenic factors PlGF and sFlt-1 can differently predict the timing of delivery of pregnancies complicated by SGA fetuses.
Background
Coronavirus disease (COVID-19) has a severe impact on all aspects of patient care. Among the numerous biomarkers of potential validity for diagnostic and clinical management of COVID-19 are biomarkers at the interface of iron metabolism and inflammation.
Methods
The follow-up study included 54 hospitalized patients with laboratory-confirmed COVID-19 with a moderate and severe/critical form of the disease. Iron deficiency specific biomarkers such as iron, ferritin, transferrin receptor, hepcidin, and zinc protoporphyrin (ZnPP) as well as relevant markers of inflammation were evaluated twice: in the first five days when the patient was admitted to the hospital and during five to 15 days; and their validity to diagnose iron deficiency was further assessed. The regression and Receiver Operating Characteristics (ROC) analyses were performed to evaluate the prognosis and determine the probability for predicting the severity of the disease in the first five days of COVID-19.
Results
Based on hemoglobin values, anemia was observed in 21 of 54 patients. Of all iron deficiency anemia-related markers, only ZnPP was significantly elevated (P<0.001) in the anemic group. When patients were grouped according to the severity of disease, slight differences in hemoglobin or other anemia-related parameters could be observed. However, the levels of ZnPP were significantly increased in the severely ill group of patients. The ratio of ZnPP to lymphocyte count (ZnPP/L) had a discrimination power stronger than the neutrophil to lymphocyte count ratio (N/L) to determine disease severity. Additionally, only two markers were independently associated with the severity of COVID-19 in logistic regression analysis; D-dimer (OR (5.606)(95% CI 1.019–30.867)) and ZnPP/L ratio (OR (74.313) (95% CI 1.081–5108.103)).
Conclusions
For the first time ZnPP in COVID-19 patients were reported in this study. Among all iron-related markers tested, ZnPP was the only one that was associated with anemia as based on hemoglobin. The increase in ZnPP might indicate that the underlying cause of anemia in COVID-19 patients is not only due to the inflammation but also of nutritional origin. Additionally, the ZnPP/L ratio might be a valid prognostic marker for the severity of COVID-19.
Background
Coronavirus disease (COVID-19) has a severe impact on all aspects of patient care. Among the numerous biomarkers of potential validity for diagnostic and clinical management of COVID-19 are biomarkers at the interface of iron metabolism and inflammation.
Methods
The follow-up study included 54 hospitalized patients with laboratory-confirmed COVID-19 with a moderate and severe/critical form of the disease. Iron deficiency specific biomarkers such as iron, ferritin, transferrin receptor, hepcidin, and zinc protoporphyrin (ZnPP) as well as relevant markers of inflammation were evaluated twice: in the first five days when the patient was admitted to the hospital and during five to 15 days; and their validity to diagnose iron deficiency was further assessed. The regression and Receiver Operating Characteristics (ROC) analyses were performed to evaluate the prognosis and determine the probability for predicting the severity of the disease in the first five days of COVID-19.
Results
Based on hemoglobin values, anemia was observed in 21 of 54 patients. Of all iron deficiency anemia-related markers, only ZnPP was significantly elevated (P<0.001) in the anemic group. When patients were grouped according to the severity of disease, slight differences in hemoglobin or other anemia-related parameters could be observed. However, the levels of ZnPP were significantly increased in the severely ill group of patients. The ratio of ZnPP to lymphocyte count (ZnPP/L) had a discrimination power stronger than the neutrophil to lymphocyte count ratio (N/L) to determine disease severity. Additionally, only two markers were independently associated with the severity of COVID-19 in logistic regression analysis; D-dimer (OR (5.606)(95% CI 1.019–30.867)) and ZnPP/L ratio (OR (74.313) (95% CI 1.081–5108.103)).
Conclusions
For the first time ZnPP in COVID-19 patients were reported in this study. Among all iron-related markers tested, ZnPP was the only one that was associated with anemia as based on hemoglobin. The increase in ZnPP might indicate that the underlying cause of anemia in COVID-19 patients is not only due to the inflammation but also of nutritional origin. Additionally, the ZnPP/L ratio might be a valid prognostic marker for the severity of COVID-19.
Aim: To investigate the relationship of vitamin D-binding protein (GC) and genetic variation of GC (rs4588, rs7041 and rs2282679) with metabolic syndrome (MetS) in the Thai population. Materials & methods: GCglobulin concentrations were measured by quantitative western blot analysis in 401 adults. All participants were genotyped using TaqMan allelic discrimination assays. Results: GC-globulin levels were significatly lower in MetS subjects than in control subjects, in which significant negative correlations of GC-globulin levels with systolic blood pressure, glucose and age were found. Male participants who carried the GT genotype for rs4588 showed an increased risk of MetS compared with the GG wild-type (odds ratio: 3.25; p = 0.004). Conclusion: GC-globulin concentrations and variation in GC rs4588 were supported as a risk factor for MetS in Thais.
Background: Retinol binding protein 4 (RBP4), a protein secreted by adipocytes and bound in plasma to transthyretin (TTR), has been associated with obesity, the early phase of insulin resistance, metabolic syndrome, and type 2 diabetes mellitus. The objective of this study was to elucidate the relationship between RBP4, TTR, triglyceride (TG) and type 2 diabetes risk in rural Thailand. Results: RBP4 and TTR levels, as well as homeostatic model assessment of insulin resistance (HOMA-IR) values, were significantly elevated among subjects with high triglyceride levels (p < 0.01, p < 0.05, p < 0.05, respectively). Triglyceride levels correlated with RBP4 (r = 0.34, p < 0.001) and TTR (r= 0.26, p < 0.01) levels, as well as HOMA-IR values (r= 0.16, p < 0.05). After adjustment for age and gender, the risk of hypertriglyceridemia was 3.7 times greater (95% Cl =1.42 -9.73, p = 0.008) in the highest RBP4 tertile as compared to the lowest tertile. Similarly, the highest TTR and HOMA-IR tertiles had greater risk of hypertriglyceridemia at 3.5 (95% Cl = 1.30-9.20, p = 0.01) and 3.6 (95% CI = 1.33- 9.58, p = 0.01) times higher than the respective lowest tertiles. The correlation between TTR and blood glucose was statistically significant (r 0.18, p < 0.05), but not found this relationship in RBP4. Conclusions: The associations of RBP4 and TTR with hypertriglyceridemia and insulin resistance may have important implications for the risk of heart disease and stroke.
Lutein is an essential dietary carotenoid with health benefits and is inter alia responsible for the colouration of egg yolk. The relationship between lutein accumulation and egg yolk colouration was therefore studied in more detail. After feeding a low-luteine diet for 21 days, 14 birds (Lohmann brown hens aged 20 weeks) were fed a diet containing marigold (80 mg lutein/kg feed) and 14 other birds were fed a diet containing oleoresin (45 mg lutein/kg feed) for 21 days; for both groups of birds, this feeding period was followed by withdrawal for 21 days. The Roche Yolk Colour Fan (RYCF) score (0 to 15, where higher values denote greater colour intensity; R-2=0.87; P<0.01) and redness (R-2=0.89; P<0.01) increased with increasing lutein content of egg yolk. Total carotenoid content had a poor relationship with lightness (R-2=0.13; P>0.05) and yellowness (R-2=0.12; P>0.05) of the yolk. It may be concluded that increased lutein is potentially responsible for an increased RYCF score and redness (a*), but decreased yellowness (b*) and lightness (L*), of egg yolk.