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A tale of shifting relations
(2021)
Understanding the dynamics between the East Asian summer (EASM) and winter monsoon (EAWM) is needed to predict their variability under future global warming scenarios. Here, we investigate the relationship between EASM and EAWM as well as the mechanisms driving their variability during the last 10,000 years by stacking marine and terrestrial (non-speleothem) proxy records from the East Asian realm. This provides a regional and proxy independent signal for both monsoonal systems. The respective signal was subsequently analysed using a linear regression model. We find that the phase relationship between EASM and EAWM is not time-constant and significantly depends on orbital configuration changes. In addition, changes in the Atlantic Meridional Overturning circulation, Arctic sea-ice coverage, El Niño-Southern Oscillation and Sun Spot numbers contributed to millennial scale changes in the EASM and EAWM during the Holocene. We also argue that the bulk signal of monsoonal activity captured by the stacked non-speleothem proxy records supports the previously argued bias of speleothem climatic archives to moisture source changes and/or seasonality.
In this introductory chapter, the editors describe the main theoretical basis of analysis of this book and the methodological approach. The core of this book consists of 14 country-specific chapters, which allow a European comparison and show the increasing variance in migration policy approaches within and between European countries. The degree of local autonomy, the level of centralisation and the traditional forms of migration policy are factors that especially influence the possibilities for local authorities to formulate their own integration policies.
The chapter begins with a brief historical overview of Germany’s transition in the twentieth and twenty-first century from a transit and emigration country to one of immigration. The next part of this chapter looks at the challenges and problems facing German immigration policy within a multi-level federal system. Finally, the chapter gives an analysis of some of the trends in German migration policy since the refugee crisis in 2015, such as changes in the party system and in the concepts underlying migration policies to better manage, control and limit immigration to Germany.
This chapter focuses on the relationship between public opinion on migration and its media coverage. Different explanatory models, including individual characteristics, cultural factors and the impact of media and politics, have been proposed to explain public attitudes towards migrants. Understanding the local context is important, as the shares of migrants living in each region and city vary considerably. Providing correct statistical information, stressing the diversity of current migration patterns in Europe and taking part in media and public discussions are ways in which to impact public attitudes at the local level.
As expected, the traditions of national-state migration policies continue to play a very important role, path-dependence in this policy field remains high. The distribution of competences in migration policy and the integration of migrants in the nation states continues to be very different. When implementing integration strategies at grassroots level, the respective policies should be tailored to the profile of both the local migrant community and the native population. Besides better migration management in local administration and the interaction of top-down and bottom-up efforts to integrate migrants is of importance.
Introduction
(2021)
Paths Are Made by Walking
(2021)
Retinol-binding protein 4 (RBP4) is the major transport protein for retinol in blood. Recent evidence from genetic mouse models shows that circulating RBP4 derives exclusively from hepatocytes. Because RBP4 is elevated in obesity and associates with the development of glucose intolerance and insulin resistance, we tested whether a liver-specific overexpression of RBP4 in mice impairs glucose homeostasis. We used adeno-associated viruses (AAV) that contain a highly liver-specific promoter to drive expression of murine RBP4 in livers of adult mice. The resulting increase in serum RBP4 levels in these mice was comparable with elevated levels that were reported in obesity. Surprisingly, we found that increasing circulating RBP4 had no effect on glucose homeostasis. Also during a high-fat diet challenge, elevated levels of RBP4 in the circulation failed to aggravate the worsening of systemic parameters of glucose and energy homeostasis. These findings show that liver-secreted RBP4 does not impair glucose homeostasis. We conclude that a modest increase of its circulating levels in mice, as observed in the obese, insulin-resistant state, is unlikely to be a causative factor for impaired glucose homeostasis.