Refine
Has Fulltext
- no (476) (remove)
Year of publication
- 2023 (476) (remove)
Document Type
- Article (476) (remove)
Keywords
- Digitalisierung (4)
- design thinking (4)
- digital transformation (4)
- digitalization (4)
- holding capacity (4)
- machine learning (4)
- maximal isometric Adaptive Force (4)
- neuromuscular control (4)
- social media (4)
- Adaptive Force (3)
Institute
- Fachgruppe Betriebswirtschaftslehre (46)
- Historisches Institut (39)
- Institut für Biochemie und Biologie (35)
- Bürgerliches Recht (34)
- Fachgruppe Politik- & Verwaltungswissenschaft (32)
- Fachgruppe Soziologie (26)
- Fachgruppe Volkswirtschaftslehre (24)
- Strafrecht (18)
- Department Sport- und Gesundheitswissenschaften (17)
- WeltTrends e.V. Potsdam (16)
- Öffentliches Recht (16)
- Hasso-Plattner-Institut für Digital Engineering GmbH (15)
- Extern (14)
- Institut für Chemie (14)
- Department Psychologie (13)
- Institut für Germanistik (13)
- Institut für Physik und Astronomie (13)
- Institut für Geowissenschaften (12)
- Sozialwissenschaften (11)
- Wirtschaftswissenschaften (10)
- Department Linguistik (9)
- Fakultät für Gesundheitswissenschaften (7)
- Institut für Jüdische Studien und Religionswissenschaft (7)
- Institut für Jüdische Theologie (7)
- Institut für Mathematik (7)
- Institut für Umweltwissenschaften und Geographie (7)
- Department Erziehungswissenschaft (6)
- Institut für Ernährungswissenschaft (5)
- Institut für Anglistik und Amerikanistik (4)
- Department für Inklusionspädagogik (3)
- Hasso-Plattner-Institut für Digital Engineering gGmbH (3)
- Institut für Philosophie (3)
- Institut für Romanistik (3)
- Juristische Fakultät (3)
- Klassische Philologie (3)
- Lehreinheit für Wirtschafts-Arbeit-Technik (3)
- Strukturbereich Kognitionswissenschaften (3)
- Hochschulambulanz (2)
- Philosophische Fakultät (2)
- Wirtschafts- und Sozialwissenschaftliche Fakultät (2)
- Department Musik und Kunst (1)
- Institut für Informatik und Computational Science (1)
- Institut für Lebensgestaltung-Ethik-Religionskunde (1)
- MenschenRechtsZentrum (1)
- Potsdam Institute for Climate Impact Research (PIK) e. V. (1)
Großer Marktüberblick
(2023)
Der Beratermarkt ist ähnlich undurchsichtig wie der ERP-Markt selbst. Daher veröffentlichen wir in dieser Ausgabe einen umfassenden Marktüberblick zu ERP-Beratungen mit 24 Unternehmen vom Spezialisten zum Generalisten, aber immer fokussiert auf das Thema ERP. Sehr spannend ist z. B. die Bandbreite der Antworten, mit der ERP-Berater den Nutzen von ERP bei der ERP-Auswahl bewerten. Auch Auswahlportale stoßen nicht überall auf große Gegenliebe. Manche Antworten mussten aus Platzgründen leider gekürzt werden. Alle Abonnenten von ERP Management finden die vollständigen Antworten zum Download im Webauftritt.
The capillary-venous pathology cerebral cavernous malformation (CCM) is caused by loss of CCM1/Krev interaction trapped protein 1 (KRIT1), CCM2/MGC4607, or CCM3/PDCD10 in some endothelial cells. Mutations of CCM genes within the brain vasculature can lead to recurrent cerebral hemorrhages. Pharmacological treatment options are urgently needed when lesions are located in deeply-seated and in-operable regions of the central nervous system. Previous pharmacological suppression screens in disease models of CCM led to the discovery that treatment with retinoic acid improved CCM phenotypes. This finding raised a need to investigate the involvement of retinoic acid in CCM and test whether it has a curative effect in preclinical mouse models. Here, we show that components of the retinoic acid synthesis and degradation pathway are transcriptionally misregulated across disease models of CCM. We complemented this analysis by pharmacologically modifying retinoic acid levels in zebrafish and human endothelial cell models of CCM, and in acute and chronic mouse models of CCM. Our pharmacological intervention studies in CCM2-depleted human umbilical vein endothelial cells (HUVECs) and krit1 mutant zebrafish showed positive effects when retinoic acid levels were increased. However, therapeutic approaches to prevent the development of vascular lesions in adult chronic murine models of CCM were drug regiment-sensitive, possibly due to adverse developmental effects of this hormone. A treatment with high doses of retinoic acid even worsened CCM lesions in an adult chronic murine model of CCM. This study provides evidence that retinoic acid signaling is impaired in the CCM pathophysiology and suggests that modification of retinoic acid levels can alleviate CCM phenotypes.
Introduction
(2023)
House price expectations
(2023)
This study examines short-, medium-, and long-run price expectations in housing markets. At the heart of our analysis is the combination of data from a tailored in-person household survey, past sale offerings, satellite imagery on developable land, and an information treatment (RCT). As novel finding, we show that price expectations show no evidence for momentum-effects in the long run. We also do not find much evidence for behavioural biases in expectations related to individual housing tenure decisions. Confirming existing findings, we find momentum-effects in the short-run and that individuals, to a limited extend, use aggregate price information to update local expectations. Lastly, we provide suggestive evidence corroborating existing findings that expectations are relevant for portfolio choice.
New Relations in the Making?
(2023)
The educational sector currently faces a massive digital transformation with various digital offerings entering the market. To provide some orientation in this transforming space, a national digital education platform (NDEP) is under development in Germany as part of a nationwide flagship project. On the one hand, in efficiently connecting the relevant stakeholders to each other and to value-adding education-related offerings, various benefits emerge. On the other hand, monopolising the educational sector and influencing the respective market through a state-controlled platform bears potential regulatory risks from misuse of power by the platform to malpractice by the users. Against this background, we aim to identify and systematise these potential drawbacks prior to the platform’s actual development and implementation. We pursue a qualitative, interpretivist approach for policy analysis, based on ten elite interviews and two workshops. Our results are threefold: (1) We capture the consolidated NDEP architecture; (2) We categorise the range of relevant functions and value propositions of the NDEP; (3) We derive 23 regulatory areas of conflict across the three building blocks that result from the potential ecosystem and function scope configurations of the NDEP. As a contribution to research, we shed new interdisciplinary light on the governance and infrastructure of public-private platforms that enable innovation and collaboration while integrating respective market segments. As a contribution to practice, we provide clear guidance for policy-makers in strategizing the development and governance of and through national digital platforms in education.
Focusing on the passive use of Instagram, we apply the affordance perspective to deeply explore its use and use-related outcomes. In the qualitative study, we uncover the affordances of focal social media features. Two distinct groups of affordances (self- and others-oriented) emerge. Following the grounded theory methodology, we develop the affordances-actualizations-outcomes model, explaining how immediate goals associated with features translate into outcomes. In the quantitative study, we test the model by applying structural equation modeling. Our findings confirm that actualizations of self- and others-oriented affordances are associated with distinct outcomes: social connectedness, positive affect, and overall satisfaction with Instagram experience.
International institutions are an essential driving force of contemporary policies to combat gender-based violence but remain toothless if political actors do not implement them in domestic policies. How can scholars conceptualise the transposition of international gender-based violence norms into domestic policies? I argue that discourse network analysis provides a powerful conceptual and methodological extension of critical frame analysis to understand how frames shape the meaning of gender-based violence norms in multi-level institutional contexts. Frames’ normative and cognitive network structure invites combining discourse network and frame analysis techniques that locate frames’ power in their ability to connect different institutional spheres temporally and spatially. I outline a multi-level research agenda that traces the framing processes of international norms and their domestic implementation through gender-based violence policies in the Council of Europe’s Istanbul Convention. This agenda includes avenues to study how complex transnational policy frameworks like the Istanbul Convention play out in domestic policy implementation.
Although prior research has shown that reward provision might sometimes increase creativity, little is known about how leadership that clarifies effort-reward contingencies (i.e., contingent reward leadership) is related to team creativity. Drawing on the theory of learned industriousness, we argue that contingent reward leadership can enhance team knowledge exchange and, in turn, team creative performance. However, we propose that this relationship is moderated by leader unpredictability, which can create uncertainty about resource allocation, thereby undermining the otherwise positive effect of contingent reward leadership. In a two-source, lagged design (three-wave) field study with data from 60 organizational teams, we found a conditional indirect (moderated mediation) effect of contingent reward leadership on team creative performance through team knowledge exchange. This conditional indirect effect was positive when leader unpredictability was low, and negative when leader unpredictability was high. Our research provides leaders with clear and actionable advice by showing that contingent reward leadership promotes team creative performance only when leaders act in predictable and consistent ways.