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Das Paper untersucht die geopolitische Konfrontation zwischen Iran und den USA sowie deren Auswirkung auf eine Veränderung der bestehenden Weltordnung. Es wird deutlich, dass die US-amerikanische Sanktionspolitik nicht nur auf das Nuklearprogramm abzielt, sondern grundsätzlich versucht, die Wirtschaftskraft der unabhängig von den Interessen der USA agierenden Regionalmacht zu brechen. Doch die Sanktionspolitik konnte weder eine Lösung des Nukleardossiers herbeiführen noch die Wirtschaftskraft Irans eindämmen. Es ist Zeit für eine fundamentale Kursänderung.
Indoor mesocosm experiments were conducted to test for potential climate change effects on the spring succession of Baltic Sea plankton. Two different temperature (Delta 0 A degrees C and Delta 6 A degrees C) and three light scenarios (62, 57 and 49 % of the natural surface light intensity on sunny days), mimicking increasing cloudiness as predicted for warmer winters in the Baltic Sea region, were simulated. By combining experimental and modeling approaches, we were able to test for a potential dietary mismatch between phytoplankton and zooplankton. Two general predator-prey models, one representing the community as a tri-trophic food chain and one as a 5-guild food web were applied to test for the consequences of different temperature sensitivities of heterotrophic components of the plankton. During the experiments, we observed reduced time-lags between the peaks of phytoplankton and protozoan biomass in response to warming. Microzooplankton peak biomass was reached by 2.5 day A degrees C-1 earlier and occurred almost synchronously with biomass peaks of phytoplankton in the warm mesocosms (Delta 6 A degrees C). The peak magnitudes of microzooplankton biomass remained unaffected by temperature, and growth rates of microzooplankton were higher at Delta 6 A degrees C (mu(a dagger 0 A degrees C) = 0.12 day(-1) and mu(a dagger 6 A degrees C) = 0.25 day(-1)). Furthermore, warming induced a shift in microzooplankton phenology leading to a faster species turnover and a shorter window of microzooplankton occurrence. Moderate differences in the light levels had no significant effect on the time-lags between autotrophic and heterotrophic biomass and on the timing, biomass maxima and growth rate of microzooplankton biomass. Both models predicted reduced time-lags between the biomass peaks of phytoplankton and its predators (both microzooplankton and copepods) with warming. The reduction of time-lags increased with increasing Q(10) values of copepods and protozoans in the tritrophic food chain. Indirect trophic effects modified this pattern in the 5-guild food web. Our study shows that instead of a mismatch, warming might lead to a stronger match between protist grazers and their prey altering in turn the transfer of matter and energy toward higher trophic levels.
Abouzar, Maryam H. ; Poghossian, Arshak ; Cherstvy, Andrey G. ; Pedraza, Angela M. ; Ingebrandt, Sven ; Schöning, Michael J.
Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface.
The 2010 very high energy gamma-ray flare and 10 years ofmulti-wavelength oservations of M 87
(2012)
Abramowski, Attila ; Acero, F. ; Aharonian, Felix A. ; Akhperjanian, A. G. ; Anton, Gisela ; Balzer, Arnim ; Barnacka, Anna ; de Almeida, U. Barres ; Becherini, Yvonne ; Becker, J. ; Behera, B. ; Bernlöhr, K. ; Birsin, E. ; Biteau, Jonathan ; Bochow, A. ; Boisson, Catherine ; Bolmont, J. ; Bordas, Pol ; Brucker, J. ; Brun, Francois ; Brun, Pierre ; Bulik, Tomasz ; Buesching, I. ; Carrigan, Svenja ; Casanova, Sabrina ; Cerruti, M. ; Chadwick, Paula M. ; Charbonnier, A. ; Chaves, Ryan C. G. ; Cheesebrough, A. ; Clapson, A. C. ; Coignet, G. ; Cologna, Gabriele ; Conrad, Jan ; Dalton, M. ; Daniel, M. K. ; Davids, I. D. ; Degrange, B. ; Deil, C. ; Dickinson, H. J. ; Djannati-Ataï, A. ; Domainko, W. ; Drury, L. O'C. ; Dubus, G. ; Dutson, K. ; Dyks, J. ; Dyrda, M. ; Egberts, Kathrin ; Eger, P. ; Espigat, P. ; Fallon, L. ; Farnier, C. ; Fegan, S. ; Feinstein, F. ; Fernandes, M. V. ; Fiasson, A. ; Fontaine, G. ; Foerster, A. ; Fuessling, M. ; Gallant, Y. A. ; Gast, H. ; Gerard, L. ; Gerbig, D. ; Giebels, B. ; Glicenstein, J. F. ; Glueck, B. ; Goret, P. ; Goering, D. ; Haeffner, S. ; Hague, J. D. ; Hampf, D. ; Hauser, M. ; Heinz, S. ; Heinzelmann, G. ; Henri, G. ; Hermann, G. ; Hinton, James Anthony ; Hoffmann, A. ; Hofmann, W. ; Hofverberg, P. ; Holler, M. ; Horns, D. ; Jacholkowska, A. ; de Jager, O. C. ; Jahn, C. ; Jamrozy, M. ; Jung, I. ; Kastendieck, M. A. ; Katarzynski, K. ; Katz, U. ; Kaufmann, S. ; Keogh, D. ; Khangulyan, D. ; Khelifi, B. ; Klochkov, D. ; Kluzniak, W. ; Kneiske, T. ; Komin, Nu. ; Kosack, K. ; Kossakowski, R. ; Laffon, H. ; Lamanna, G. ; Lennarz, D. ; Lohse, T. ; Lopatin, A. ; Lu, C. -C. ; Marandon, V. ; Marcowith, Alexandre ; Masbou, J. ; Maurin, D. ; Maxted, N. ; Mayer, M. ; McComb, T. J. L. ; Medina, M. C. ; Mehault, J. ; Moderski, R. ; Moulin, Emmanuel ; Naumann, C. L. ; Naumann-Godo, M. ; de Naurois, M. ; Nedbal, D. ; Nekrassov, D. ; Nguyen, N. ; Nicholas, B. ; Niemiec, J. ; Nolan, S. J. ; Ohm, S. ; Wilhelmi, E. de Ona ; Opitz, B. ; Ostrowski, M. ; Oya, I. ; Panter, M. ; Arribas, M. Paz ; Pedaletti, G. ; Pelletier, G. ; Petrucci, P. -O. ; Pita, S. ; Puehlhofer, G. ; Punch, M. ; Quirrenbach, A. ; Raue, M. ; Rayner, S. M. ; Reimer, A. ; Reimer, O. ; Renaud, M. ; de los Reyes, R. ; Rieger, F. ; Ripken, J. ; Rob, L. ; Rosier-Lees, S. ; Rowell, G. ; Rudak, B. ; Rulten, C. B. ; Ruppel, J. ; Sahakian, V. ; Sanchez, David M. ; Santangelo, Andrea ; Schlickeiser, R. ; Schoeck, F. M. ; Schulz, A. ; Schwanke, U. ; Schwarzburg, S. ; Schwemmer, S. ; Sheidaei, F. ; Skilton, J. L. ; Sol, H. ; Spengler, G. ; Stawarz, L. ; Steenkamp, R. ; Stegmann, Christian ; Stinzing, F. ; Stycz, K. ; Sushch, Iurii ; Szostek, A. ; Tavernet, J. -P. ; Terrier, R. ; Tluczykont, M. ; Valerius, K. ; van Eldik, C. ; Vasileiadis, G. ; Venter, C. ; Vialle, J. P. ; Viana, A. ; Vincent, P. ; Voelk, H. J. ; Volpe, F. ; Vorobiov, S. ; Vorster, M. ; Wagner, S. J. ; Ward, M. ; White, R. ; Wierzcholska, A. ; Zacharias, M. ; Zajczyk, A. ; Zdziarski, A. A. ; Zech, Alraune ; Zechlin, H. -S. ; Aleksic, J. ; Antonelli, L. A. ; Antoranz, P. ; Backes, Michael ; Barrio, J. A. ; Bastieri, D. ; Becerra Gonzalez, J. ; Bednarek, W. ; Berdyugin, A. ; Berger, K. ; Bernardini, E. ; Biland, A. ; Blanch Bigas, O. ; Bock, R. K. ; Boller, A. ; Bonnoli, G. ; Tridon, D. Borla ; Braun, I. ; Bretz, T. ; Canellas, A. ; Carmona, E. ; Carosi, A. ; Colin, P. ; Colombo, E. ; Contreras, J. L. ; Cortina, J. ; Cossio, L. ; Covino, S. ; Dazzi, F. ; De Angelis, A. ; De Cea del Pozo, E. ; De Lotto, B. ; Delgado Mendez, C. ; Diago Ortega, A. ; Doert, M. ; Dominguez, A. ; Prester, Dijana Dominis ; Dorner, D. ; Doro, M. ; Elsaesser, D. ; Ferenc, D. ; Fonseca, M. V. ; Font, L. ; Fruck, C. ; Garcia Lopez, R. J. ; Garczarczyk, M. ; Garrido, D. ; Giavitto, G. ; Godinovic, N. ; Hadasch, D. ; Haefner, D. ; Herrero, A. ; Hildebrand, D. ; Hoehne-Moench, D. ; Hose, J. ; Hrupec, D. ; Huber, B. ; Jogler, T. ; Klepser, S. ; Kraehenbuehl, T. ; Krause, J. ; La Barbera, A. ; Lelas, D. ; Leonardo, E. ; Lindfors, E. ; Lombardi, S. ; Lopez, M. ; Lorenz, E. ; Makariev, M. ; Maneva, G. ; Mankuzhiyil, N. ; Mannheim, K. ; Maraschi, L. ; Mariotti, M. ; Martinez, M. ; Mazin, D. ; Meucci, M. ; Miranda, J. M. ; Mirzoyan, R. ; Miyamoto, H. ; Moldon, J. ; Moralejo, A. ; Munar, P. ; Nieto, D. ; Nilsson, K. ; Orito, R. ; Oya, I. ; Paneque, D. ; Paoletti, R. ; Pardo, S. ; Paredes, J. M. ; Partini, S. ; Pasanen, M. ; Pauss, F. ; Perez-Torres, M. A. ; Persic, M. ; Peruzzo, L. ; Pilia, M. ; Pochon, J. ; Prada, F. ; Moroni, P. G. Prada ; Prandini, E. ; Puljak, I. ; Reichardt, I. ; Reinthal, R. ; Rhode, W. ; Ribo, M. ; Rico, J. ; Ruegamer, S. ; Saggion, A. ; Saito, K. ; Saito, T. Y. ; Salvati, M. ; Satalecka, K. ; Scalzotto, V. ; Scapin, V. ; Schultz, C. ; Schweizer, T. ; Shayduk, M. ; Shore, S. N. ; Sillanpaa, A. ; Sitarek, J. ; Sobczynska, D. ; Spanier, F. ; Spiro, S. ; Stamerra, A. ; Steinke, B. ; Storz, J. ; Strah, N. ; Suric, T. ; Takalo, L. ; Takami, H. ; Tavecchio, F. ; Temnikov, P. ; Terzic, T. ; Tescaro, D. ; Teshima, M. ; Thom, M. ; Tibolla, O. ; Torres, D. F. ; Treves, A. ; Vankov, H. ; Vogler, P. ; Wagner, R. M. ; Weitzel, Q. ; Zabalza, V. ; Zandanel, F. ; Zanin, R. ; Arlen, T. ; Aune, T. ; Beilicke, M. ; Benbow, W. ; Bouvier, A. ; Bradbury, S. M. ; Buckley, J. H. ; Bugaev, V. ; Byrum, K. ; Cannon, A. ; Cesarini, A. ; Ciupik, L. ; Connolly, M. P. ; Cui, W. ; Dickherber, R. ; Duke, C. ; Errando, M. ; Falcone, A. ; Finley, J. P. ; Finnegan, G. ; Fortson, L. ; Furniss, A. ; Galante, N. ; Gall, D. ; Godambe, S. ; Griffin, S. ; Grube, J. ; Gyuk, G. ; Hanna, D. ; Holder, J. ; Huan, H. ; Hui, C. M. ; Kaaret, P. ; Karlsson, N. ; Kertzman, M. ; Khassen, Y. ; Kieda, D. ; Krawczynski, H. ; Krennrich, F. ; Lang, M. J. ; LeBohec, S. ; Maier, G. ; McArthur, S. ; McCann, A. ; Moriarty, P. ; Mukherjee, R. ; Nunez, P. D. ; Ong, R. A. ; Orr, M. ; Otte, A. N. ; Park, N. ; Perkins, J. S. ; Pichel, A. ; Pohl, Martin ; Prokoph, H. ; Ragan, K. ; Reyes, L. C. ; Reynolds, P. T. ; Roache, E. ; Rose, H. J. ; Ruppel, J. ; Schroedter, M. ; Sembroski, G. H. ; Sentuerk, G. D. ; Telezhinsky, Igor O. ; Tesic, G. ; Theiling, M. ; Thibadeau, S. ; Varlotta, A. ; Vassiliev, V. V. ; Vivier, M. ; Wakely, S. P. ; Weekes, T. C. ; Williams, D. A. ; Zitzer, B. ; de Almeida, U. Barres ; Cara, M. ; Casadio, C. ; Cheung, C. C. ; McConville, W. ; Davies, F. ; Doi, A. ; Giovannini, G. ; Giroletti, M. ; Hada, K. ; Hardee, P. ; Harris, D. E. ; Junor, W. ; Kino, M. ; Lee, N. P. ; Ly, C. ; Madrid, J. ; Massaro, F. ; Mundell, C. G. ; Nagai, H. ; Perlman, E. S. ; Steele, I. A. ; Walker, R. C. ; Wood, D. L.
The giant radio galaxy M 87 with its proximity (16 Mpc), famous jet, and very massive black hole ((3-6) x 10(9) M-circle dot) provides a unique opportunity to investigate the origin of very high energy (VHE; E > 100 GeV) gamma-ray emission generated in relativistic outflows and the surroundings of supermassive black holes. M 87 has been established as a VHE gamma-ray emitter since 2006. The VHE gamma-ray emission displays strong variability on timescales as short as a day. In this paper, results from a joint VHE monitoring campaign on M 87 by the MAGIC and VERITAS instruments in 2010 are reported. During the campaign, a flare at VHE was detected triggering further observations at VHE (H.E.S.S.), X-rays (Chandra), and radio (43 GHz Very Long Baseline Array, VLBA). The excellent sampling of the VHE gamma-ray light curve enables one to derive a precise temporal characterization of the flare: the single, isolated flare is well described by a two-sided exponential function with significantly different flux rise and decay times of tau(rise)(d) = (1.69 +/- 0.30) days and tau(decay)(d) = (0.611 +/- 0.080) days, respectively. While the overall variability pattern of the 2010 flare appears somewhat different from that of previous VHE flares in 2005 and 2008, they share very similar timescales (similar to day), peak fluxes (Phi(>0.35 TeV) similar or equal to (1-3) x 10(-11) photons cm(-2) s(-1)), and VHE spectra. VLBA radio observations of 43 GHz of the inner jet regions indicate no enhanced flux in 2010 in contrast to observations in 2008, where an increase of the radio flux of the innermost core regions coincided with a VHE flare. On the other hand, Chandra X-ray observations taken similar to 3 days after the peak of the VHE gamma-ray emission reveal an enhanced flux from the core (flux increased by factor similar to 2; variability timescale <2 days). The long-term (2001-2010) multi-wavelength (MWL) light curve of M 87, spanning from radio to VHE and including data from Hubble Space Telescope, Liverpool Telescope, Very Large Array, and European VLBI Network, is used to further investigate the origin of the VHE gamma-ray emission. No unique, common MWL signature of the three VHE flares has been identified. In the outer kiloparsec jet region, in particular in HST-1, no enhanced MWL activity was detected in 2008 and 2010, disfavoring it as the origin of the VHE flares during these years. Shortly after two of the three flares (2008 and 2010), the X-ray core was observed to be at a higher flux level than its characteristic range (determined from more than 60 monitoring observations: 2002-2009). In 2005, the strong flux dominance of HST-1 could have suppressed the detection of such a feature. Published models for VHE gamma-ray emission from M 87 are reviewed in the light of the new data.
Weltweit brodelt es, Bürger gehen auf die Straße. In Chile will man sich die Ungerechtigkeiten des Bildungssystems nicht länger gefallen lassen. Nur wer zahlt, darf lernen – dagegen wehrt sich vor allem die Jugend mit aller Macht, auch mit der Macht der Neuen Medien. Öffentlichkeitswirksam werden die Proteste inszeniert. Wird die chilenische Regierung weiterhin mit Knüppeln auf Demonstranten einschlagen oder einlenken?
The closer the better
(2012)
Adam, Jos J. ; Bovend'Eerdt, Thamar J. H. ; Dooren, Fleur E. P. van ; Fischer, Martin H. ; Pratt, Jay
A growing literature has suggested that processing of visual information presented near the hands is facilitated. In this study, we investigated whether the near-hands superiority effect also occurs with the hands moving. In two experiments, participants performed a cyclical bimanual movement task requiring concurrent visual identification of briefly presented letters. For both the static and dynamic hand conditions, the results showed improved letter recognition performance with the hands closer to the stimuli. The finding that the encoding advantage for near-hand stimuli also occurred with the hands moving suggests that the effect is regulated in real time, in accordance with the concept of a bimodal neural system that dynamically updates hand position in external space.
Adam, Jos J. ; Bovend'Eerdt, Thamar J. H. ; van Dooren, Fleur E. P. ; Fischer, Martin H. ; Pratt, Jay
A growing literature has suggested that processing of visual information presented near the hands is facilitated. In this study, we investigated whether the near-hands superiority effect also occurs with the hands moving. In two experiments, participants performed a cyclical bimanual movement task requiring concurrent visual identification of briefly presented letters. For both the static and dynamic hand conditions, the results showed improved letter recognition performance with the hands closer to the stimuli. The finding that the encoding advantage for near-hand stimuli also occurred with the hands moving suggests that the effect is regulated in real time, in accordance with the concept of a bimodal neural system that dynamically updates hand position in external space.
In both eukaryotic and prokaryotic DNA sequences of 30-100 base-pairs rich in AT base-pairs have been identified at which the double helix preferentially unwinds. Such DNA unwinding elements are commonly associated with origins for DNA replication and transcription, and with chromosomal matrix attachment regions. Here we present a quantitative study of local DNA unwinding based on extensive single DNA plasmid imaging. We demonstrate that long-lived single-stranded denaturation bubbles exist in negatively supercoiled DNA, at the expense of partial twist release. Remarkably, we observe a linear relation between the degree of supercoiling and the bubble size, in excellent agreement with statistical modelling. Furthermore, we obtain the full distribution of bubble sizes and the opening probabilities at varying salt and temperature conditions. The results presented herein underline the important role of denaturation bubbles in negatively supercoiled DNA for biological processes such as transcription and replication initiation in vivo.