Refine
Year of publication
- 2013 (141) (remove)
Document Type
- Article (98)
- Postprint (20)
- Doctoral Thesis (17)
- Habilitation Thesis (2)
- Review (2)
- Master's Thesis (1)
- Other (1)
Language
- English (141) (remove)
Keywords
- biomaterials (3)
- ligand (3)
- photoisomerization (3)
- Crystal structure (2)
- DFT calculations (2)
- Density functional calculations (2)
- Hydrogel (2)
- ICSS (2)
- Ion mobility spectrometry (2)
- Ionic Liquid (2)
- Mass spectrometry (2)
- Nanopartikel (2)
- OTDR (2)
- Push-pull character (2)
- REMPI (2)
- TSNMRS (2)
- adsorption (2)
- anomalous diffusion (2)
- aqueous-solution (2)
- atropisomerism (2)
- carbon-dioxide (2)
- carbon-dioxide capture (2)
- dynamic HPLC (2)
- dynamic NMR (2)
- ionic liquid (2)
- ionic liquids (2)
- metal-organic frameworks (2)
- molecular oxygen (2)
- nanoparticles (2)
- naphthalenophanes (2)
- optical sensing (2)
- palladium (2)
- phase-transitions (2)
- photo-dehydro-Diels-Alder reaction (2)
- stimuli-sensitive polymers (2)
- triangular-[4] phenylene (2)
- zinc (2)
- (Anti)aromaticity (1)
- -Acetoxy esters (1)
- 1,2,4-Dithiazole (1)
- 1,2-Disulfonamides (1)
- 1,2-Dithiole (1)
- 10-Methoxy-10,7 '-(chrysophanol anthrone)-chrysophanol (1)
- 2-Alkylidene-4-oxothiazolidine (1)
- 3,4-Dihydroisoquinoline (1)
- 3-Hydroxyisoflavanone (1)
- 4-Nitrophenol (1)
- 4-Oxothiazolidine (1)
- Ab-initio calculations (1)
- Activation parameters (1)
- Adsorbent (1)
- Adsorption (1)
- Allylamides (1)
- Alumina (1)
- Aminonaphthol (1)
- Amphiphiles (1)
- Anisotropic effect (1)
- Anthraquinone (1)
- Antiplasmodial activity (1)
- Aromaticity (1)
- Asphodelaceae (1)
- Asteraceae (1)
- Atropisomerism (1)
- Barrier to ring inversion (1)
- Biochromophore (1)
- Bioelectrocatalysis (1)
- Bioinspired (1)
- Biomimetics (1)
- Boric acid (1)
- Bulk-mediated diffusion (1)
- C-13 NMR spectroscopy (1)
- C?H oxidation (1)
- CH center dot center dot center dot O hydrogen bonds (1)
- Calcium phosphate (1)
- Car-Parrinello (1)
- Carbenes (1)
- Carbide (1)
- Carbides (1)
- Carboxyfluorescein (1)
- Carboxyrhodamine (1)
- Cation exchange Capacity (1)
- Cellulose (1)
- Chelation effect (1)
- Chiral auxiliaries (1)
- Cobalt (1)
- Composites (1)
- Conformational analysis (1)
- Conformational equilibrium (1)
- Continuum properties (1)
- Copper(II) complexes (1)
- Core-shell-corona micelles (1)
- Cross-metathesis (1)
- Cryo-TEM (1)
- Cyclodienes (1)
- Cyclophanes (1)
- Dalbergia melanoxylon (1)
- Dehydro[n]annulenes (1)
- Diaminomaleonitrile (1)
- Dianellin (1)
- Diastereoselectivity (1)
- Diffusion processes (1)
- Direct electron transfer (1)
- Docking (1)
- Double exponential model (1)
- Drop morphology (1)
- Dynamic NMR spectroscopy (1)
- EPR (1)
- Electron dynamics (1)
- Electrospinning (1)
- Electrostatic effects (1)
- Elektronendynamik (1)
- Equilibrium constants (1)
- Extraction (1)
- Fatty acids (1)
- Fiber (1)
- Field flow fractionation (1)
- Filtration (1)
- Fluorescence (1)
- Formation constant (1)
- Forster resonance energy transfer (FRET) (1)
- Gas Sorption (1)
- Gas chromatography (1)
- Glycopeptoid (1)
- Gold cluster (1)
- H-1 NMR spectroscopy (1)
- Heck reaction (1)
- Hybrid clay (1)
- Hydrogel microspheres (1)
- Hydrogen Production (1)
- Hydrogen sulfide (1)
- Hydrothermale Karbonisierung (1)
- Immobilization (1)
- Interphase behavior (1)
- Ionic strength (1)
- Ionogel (1)
- Janus emulsions (1)
- Kaolinite (1)
- Katalyse (1)
- Kenusanone F 7-methyl ether (1)
- Kinetics (1)
- Kniphofia foliosa (1)
- Knipholone cyclooxanthrone (1)
- Kohlenstoffe auf Biomasse-Basis (1)
- Komposite (1)
- LCST behavior (1)
- Laser ionization (1)
- Laser-SNMS (1)
- Laserpulskontrolle (1)
- Levy flights (1)
- Macrocycles (1)
- Malaria (1)
- Matsuda-Heck reaction (1)
- Mesh size (1)
- Metal-organic framework (1)
- Microemulsion (1)
- Mineralization (1)
- Molecular rods (1)
- Multicompartment micelles (1)
- Multilayers (1)
- Mycobacterium tuberculosis (1)
- N-acetyl cysteine (1)
- NBO and STERIC analyses (1)
- NCA (1)
- Nanoparticles (1)
- Network structure (1)
- Neuroleptics (1)
- Nicotinamide (1)
- PQQ-dependent glucose dehydrogenase (1)
- Palladium (1)
- Pd catalysis (1)
- Perylene (1)
- Polar effect (1)
- Polyelectrolytes (1)
- Polyglycin (1)
- Polymer capped gold nanoparticles (1)
- Polymers (1)
- Protein delivery (1)
- Proton transfer reaction (1)
- Push-pull allenes (1)
- Pyrene (1)
- Quotient method (1)
- RAFT (1)
- Raman spectroscopy (1)
- Rearrangement to trithiaazapentalene (1)
- Release studies (1)
- Rhodium (1)
- Roots (1)
- SAXS (1)
- Senecio roseiflorus (1)
- Silacyclohexanes (1)
- Silaheterocyclohexanes (1)
- Silver (1)
- Sophoronol-7-methyl ether (1)
- Steric effect (1)
- Steric effects (1)
- Steric substituent constant (1)
- Substrate effect (1)
- Sulfonated polyaniline (1)
- Sulfoxide (1)
- Surface complexes (1)
- Surface exudates (1)
- Suzuki coupling (1)
- Swelling behavior (1)
- Synthesis (1)
- Synthetic methods (1)
- Taft equation (1)
- Theoretical calculations (1)
- Thermo-responsive (1)
- Thermochemical properties (1)
- Thin film (1)
- Thioether ligands (1)
- Threshold (1)
- ToF-SIMS (1)
- Transitionmetals (1)
- Trifluoromethanesulfonamide (1)
- Triphilic block copolymers (1)
- Trithiapentalene (1)
- Untreated agricultural wastes (1)
- Water treatment (1)
- Water vapor (1)
- X-ray (1)
- X-ray diffraction (1)
- Zellulose (1)
- Zinc (1)
- a (1)
- ab initio (1)
- acetanilides (1)
- adamantane (1)
- air-water-interface (1)
- alignment (1)
- alkynol cycloisomerization (1)
- amorphous polymers (1)
- anionic polymerizations (1)
- antibodies (1)
- antioxidants (1)
- arenediazonium salts (1)
- arenes (1)
- arylboronic acids (1)
- aryldiazonium salts (1)
- aspect-ratio (1)
- assemblies (1)
- azobenzene (1)
- behavior (1)
- binding (1)
- biochromophores (1)
- biomass-derived carbons (1)
- biopolymers (1)
- biorelevant (1)
- block-copolymers (1)
- borates (1)
- boronic acid (1)
- building-blocks (1)
- capacity (1)
- carbohydrate-based oxepines (1)
- carbon (1)
- carbonyl-compounds (1)
- carbothermal (1)
- carbothermisch (1)
- catalysis (1)
- catalyzed cross metathesis (1)
- catalyzed redox isomerization (1)
- cationic surfactants (1)
- chain azobenzene polymers (1)
- charge transfer (1)
- chemical-synthesis (1)
- chiral recognition (1)
- chiral switches (1)
- chirale Erkennung (1)
- chirale Schalter (1)
- click chemistry (1)
- clusters (1)
- cobalt (1)
- coffee phenolic compounds (1)
- complex (1)
- complexes (1)
- conjugated microporous polymers (1)
- continuous-flow (1)
- coordination polymer (1)
- copper(II) halide salts (1)
- covalent organic framework (1)
- covalent organic frameworks (1)
- crown compounds (1)
- crystals (1)
- data-storage (1)
- de-novo synthesis (1)
- deacetylation (1)
- decay dynamics (1)
- delivery (1)
- density functional theory (DFT) (1)
- diazo compounds (1)
- diazonium salts (1)
- diels-alder reaction (1)
- dienes (1)
- dilute aqueous-solutions (1)
- disordered media (1)
- dye (1)
- dyes (1)
- efficient (1)
- electron dynamics (1)
- electron transfer (1)
- electron-spin resonance (1)
- emulsion inversion (1)
- energy density (1)
- enzyme catalysis (1)
- equilibrium topology (1)
- ether methacrylates (1)
- exchange (1)
- flexibility (1)
- fluorescence (1)
- fluorescent probes (1)
- fractional dynamics (1)
- fulgides (1)
- functionalizing proteins (1)
- gas sorption (1)
- gases (1)
- gels (1)
- glass-transition temperature (1)
- glycopeptoid (1)
- gold nanoparticles (1)
- green chemistry (1)
- grüne Chemie (1)
- hemibond (1)
- heteroatom (1)
- heterogeneous catalysis (1)
- holographic diffraction gratings (1)
- homogeneous catalysis (1)
- hydrogel (1)
- hydrogels (1)
- hydrogen storage (1)
- hydrophobic mismatch (1)
- hydrothermal carbonization (1)
- hydroxyl radical (1)
- imaging (1)
- immobilization (1)
- implementation (1)
- in-situ (1)
- infection pathway (1)
- inhomogeneous-media (1)
- interactions (1)
- interfaces (1)
- intracellular-transport (1)
- intramolecular charge-transfer (1)
- intrinsic microporosity (1)
- ion exchange (1)
- ionothermal synthesis (1)
- isotope effects (1)
- janus emulsions (1)
- lactones (1)
- langevin equation (1)
- laser chemistry (1)
- laser pulse control (1)
- life sciences (1)
- light (1)
- lipidomics (1)
- liquid-crystal precursors (1)
- liquids (1)
- living cells (1)
- magnetic-properties (1)
- membranes (1)
- metal ions (1)
- metal nanoparticles (1)
- metal-organic framework (1)
- metathesis (1)
- microfluidics (1)
- mineralization beneath (1)
- mixed-matrix membranes (1)
- mixtures (1)
- modeling (1)
- models (1)
- modulation (1)
- molecular modeling (1)
- molecular rods (1)
- molecular-dynamics (1)
- molecular-reorientation (1)
- molecular-structure (1)
- molecules (1)
- morphology (1)
- multifunctional polymers (1)
- multiple emulsion preparation (1)
- n-heterocyclic carbenes (1)
- n-isopropylacrylamide (1)
- natural products (1)
- networks (1)
- nucleation (1)
- o bond formation (1)
- olefin-metathesis (1)
- oligo(ethylene glycol) methacrylate (1)
- opal (1)
- orthophosphates (1)
- oxidative stress (1)
- palladium catalyst (1)
- paramagnetic-resonance (1)
- peroxides (1)
- phagocytosis (1)
- phenanthrenes (1)
- phospholipids (1)
- photochemical synthesis (1)
- photoinduced nonadiabatic dynamics (1)
- poly(acrylamide) hydrogels (1)
- poly(ethylene glycol) (1)
- polycationic monolayer (1)
- polyesters (1)
- polyglycine (1)
- potassium (1)
- pressure (1)
- protein (1)
- protein adsorption (1)
- protein interactions (1)
- protein-kinase inhibitors (1)
- protein-phenol interactions (1)
- pump-probe (1)
- quantum dynamics (1)
- random-walks (1)
- reduction (1)
- responsive (1)
- responsive polymers (1)
- ring-closing metathesis (1)
- ring-closure (1)
- ruthenium (1)
- ruthenium carbene (1)
- sandwich complexes (1)
- selectivity (1)
- semiempirical calculations (1)
- semiempirical methods (1)
- sensitivity (1)
- sensor (1)
- sensors (1)
- separation (1)
- shape (1)
- shape-memory polymers (1)
- shape-memory properties (1)
- silver nanoparticles (1)
- silver nanowires (1)
- single-particle tracking (1)
- singlet oxygen (1)
- sol-gel (1)
- solvatochromic fluorophore (1)
- solvent (1)
- spectroscopy (1)
- spiro compounds (1)
- square planar (1)
- state (1)
- states (1)
- statistical copolymers (1)
- stereoselective-synthesis (1)
- stochastic processes (1)
- substituted stilbenes (1)
- sulfoxides (1)
- supercapacitor (1)
- surface (1)
- surface chemistry (1)
- surface functionalization (1)
- surface-plasmon resonance (1)
- system (1)
- temperature (1)
- temperature phase (1)
- tetrachlorocuprate(II) salts (1)
- thermochemistry (1)
- thermomechanical properties (1)
- thermometer (1)
- thermoresponsiv (1)
- thermoresponsive (1)
- thermoresponsive materials (1)
- thermoresponsive polymers (1)
- thermosensitive (1)
- thin-films (1)
- three-dimensional depth profiling (1)
- thrombocyte adhesion (1)
- time-dependent configuration interaction (1)
- to-coil transition (1)
- trans-stilbenes (1)
- transformation (1)
- transition metal (1)
- triple-shape effect (1)
- ultrafast reactions (1)
- water-soluble polymers (1)
- weakly coordinating ions (1)
- whey proteins (1)
- zeolitic imidazolate frameworks (1)
- Übergangsmetall (1)
- Übergangsmetalle (1)
Institute
- Institut für Chemie (141) (remove)
4-Phenol diazonium salts undergo Pd-catalyzed Heck reactions with various styrenes to 4'-hydroxy stilbenes. In almost all cases higher yields and fewer side products were observed, compared to the analogous 4-methoxy benzene diazonium salts. In contrast, the reaction fails completely with 2- and 3-phenol diazonium salts. For these substitution patterns the methoxy-substituted derivatives are superior.
Silver nanoparticles (SNP) are among the most commercialized nanoparticles. Here, we show that peptide-coated SNP cause functional impairment of human macrophages. A dose-dependent inhibition of phagocytosis is observed after nanoparticle treatment, and pretreatment of cells with N-acetyl cysteine (NAC) can counteract the phagocytosis disturbances caused by SNP.
Using the surface-sensitive mode of time-of-flight secondary ion mass spectrometry, in combination with multivariate statistical methods, we studied the composition of cell membranes in human macrophages upon exposure to SNP with and without NAC preconditioning. This method revealed characteristic changes in the lipid pattern of the cellular membrane outer leaflet in those cells challenged by SNP. Statistical analyses resulted in 19 characteristic ions, which can be used to distinguish between NAC pretreated and untreated macrophages. The present study discusses the assignments of surface cell membrane phospholipids for the identified ions and the resulting changes in the phospholipid pattern of treated cells. We conclude that the adverse effects in human macrophages caused by SNP can be partially reversed through NAC administration. Some alterations, however, remained.
Silver nanoparticles (SNPs) are among the most commercialized nanoparticles because of their antibacterial effects. Besides being employed, e. g. as a coatingmaterial for sterile surfaces in household articles and appliances, the particles are also used in a broad range of medical applications. Their antibacterial properties make SNPs especially useful for wound disinfection or as a coating material for prostheses and surgical instruments. Because of their optical characteristics, the particles are of increasing interest in biodetection as well. Despite the widespread use of SNPs, there is little knowledge of their toxicity. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) and laser post-ionization secondary neutral mass spectrometry (Laser-SNMS) were used to investigate the effects of SNPs on human macrophages derived from THP-1 cells in vitro. For this purpose, macrophages were exposed to SNPs. The SNP concentration ranges were chosen with regard to functional impairments of the macrophages. To optimize the analysis of the macrophages, a special silicon wafer sandwich preparation technique was employed; ToF-SIMS was employed to characterize fragments originating from macrophage cell membranes. With the use of this optimized sample preparation method, the SNP-exposed macrophages were analyzed with ToF-SIMS and with Laser-SNMS. With Laser-SNMS, the three-dimensional distribution of SNPs in cells could be readily detected with very high efficiency, sensitivity, and submicron lateral resolution. We found an accumulation of SNPs directly beneath the cell membrane in a nanoparticular state as well as agglomerations of SNPs inside the cells.
Cross metathesis of allyl alcohols how to suppress and how to promote double bond isomerization
(2013)
Under standard conditions the cross metathesis of allyl alcohols and methyl acrylate is accompanied by the formation of ketones, resulting from uncontrolled and undesired double bond isomerization. By conducting the CM in the presence of phenol, the catalyst loading and the reaction time required for quantiative conversion can be reduced, and isomerization can be suppressed. On the other hand, consecutive isomerization can be deliberately promoted by evaporating excess methyl acrylate after completing cross metathesis and by adding a base or silane as chemical triggers.
Calcium phosphate nanofibers with a diameter of only a few nanometers and a cotton-ball-like aggregate morphology have been reported several times in the literature. Although fiber formation seems reproducible in a variety of conditions, the crystal structure and chemical composition of the fibers have been elusive. Using scanning transmission electron microscopy, low dose electron (nano) diffraction, energy-dispersive X-ray spectroscopy, and energy-filtered transmission electron microscopy, we have assigned crystal structures and chemical compositions to the fibers. Moreover, we demonstrate that the mineralization process yields true polymer/calcium phosphate hybrid materials where the block copolymer template is closely associated with the calcium phosphate.
Sugar-based molecules and polysaccharide biomass can be turned into porous functional carbonaceous products at comparably low temperatures of 400 degrees C under a nitrogen atmosphere in the presence of an ionic liquid (IL) or a poly(ionic liquid) (PIL). The IL and PIL act as "activation agents" with own structural contribution, and effectively promote the conversion and pore generation in the biomaterials even at a rather low doping ratio (7 wt%). In addition, this "induced carbonization" and pore forming phenomenon enables the preservation of the biotemplate shape to the highest extent and was employed to fabricate shaped porous carbonaceous materials from carbohydrate-based biotemplates, exemplified here with cellulose filter membranes, coffee filter paper and natural cotton. These carbonized hybrids exhibit comparably good mechanical properties, such as bendability of membranes or shape recovery of foams. Moreover, the nitrogen atoms incorporated in the final products from the IL/PIL precursors further improve the oxidation stability in the fire-retardant tests.
A rare example of in situ linker generation with the formation of soft porous Zn- and Co-MOFs (IFP-9 and -10, respectively) is reported. The flexible ethoxy groups of IFP-9 and -10 protrude into the 1D hexagonal channels. The gas-sorption behavior of both materials for H-2, CO2 and CH4 showed wide hysteretic isotherms, typical for MOFs having a flexible substituent which can give rise to a gate effect.
Transcriptome analysis through next-generation sequencing technologies allows the generation of detailed gene catalogs for non-model species, at the cost of new challenges with regards to computational requirements and bioinformatics expertise. Here, we present TRAPID, an online tool for the fast and efficient processing of assembled RNA-Seq transcriptome data, developed to mitigate these challenges. TRAPID offers high-throughput open reading frame detection, frameshift correction and includes a functional, comparative and phylogenetic toolbox, making use of 175 reference proteomes. Benchmarking and comparison against state-of-the-art transcript analysis tools reveals the efficiency and unique features of the TRAPID system.